90 results about "Truncal muscle weakness" patented technology

A method for treating spasticity of a subject is provided, including driving a current into a nerve of the subject that includes one or more sensory fibers, and configuring the current so as to inhibit propagation of action potentials in one or more of the sensory fibers, so as to treat the spasticity. In a preferred embodiment, the sensory fibers include one or more Ia sensory fibers, and configuring the current includes configuring the current so as to inhibit propagation of the action potentials in at least one of the Ia sensory fibers.

A portable electrical motor-driven exoskeleton ankle joint robot with gear transmission and control system which is intended to provide walking assistance in different speed and walking conditions to persons with disability in walking or muscle weakness or joint problem.

A method for treating spasticity of a subject is provided, including driving a current into a nerve of the subject that includes one or more sensory fibers, and configuring the current so as to inhibit propagation of action potentials in one or more of the sensory fibers, so as to treat the spasticity. In a preferred embodiment, the sensory fibers include one or more Ia sensory fibers, and configuring the current includes configuring the current so as to inhibit propagation of the action potentials in at least one of the Ia sensory fibers.

Passive gravity balancing orthosis apparatus for assisting and training patients suffering from muscle weakness by relieving the patients afflicted member of its weight using a plurality of articulated supporting members. Relief is obtained by identifying and fixing the center of mass of the combined articulated equipment members and supported weight of the patient's member in space using a defined parallelogram mechanism and once so identified making the total potential energy for any configuration of the articulated members of the system constant. At least one zero free length spring is used to connect the center of mass to a support outside the articulated members. Additional springs connect the center of mass to the articulated members.

The present invention provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of an Androgen Deficiency in Female (ADIF)-associated condition in a female subject, by administering to the subject a selective androgen receptor modulator (SARM) compound and / or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, crystal, polymorph, prodrug, or any combination thereof. The present invention further provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, fatigue, depression, anemia, muscle weakness, hair loss, obesity, polycystic ovarian disease, endometriosis, breast cancer, uterine cancer and ovarian cancer due to ADIF in a female subject, by administering to the subject a selective androgen receptor modulator (SARM) compound and / or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, crystal, polymorph, prodrug, or any combination thereof.

The invention provides a sports nutritional candy which adds creatine, carbohydrates, peptides, amino acid, minerals and vitamins in different types of candies. The sports nutritional candy of the invention has functions of muscle development and improving sports ability obviously, has rich nutrition, small volume, light weight, good taste and is convenient for carrying and application, can meet the requirements of promoting muscle development, supplying energy during sports and replenishing nutrition for professional athletes, body-building fans, bodybuilding fans, school students, seniors suffering from muscle weakness and people who love sports. The sports nutritional candy can promote muscle development and supply energy and strength to people who do sports.

A method, system and apparatus for detecting a disorder of the central nervous system, comprises: recording an EMG from muscle groups on left and right hands of patient; separating a gesture writing action into time intervals of postural and writing activity; recording EMG activity from the same muscle groups during a resting time period; determining a plurality of indicators, comprising: identifying tremor peaks in EMG spectral density; determining muscle tone like stiffness from EMG spectral density determining muscle weakness from EMG intensities; determining patterns of correlation waves; determining a delay from when a subject started writing after hearing an audio signal; determining the time of writing activity, when a pen is touching a tablet; determining the heights and shapes of characters from pen traces on a tablet; and assigning a point value to every indicator and calculating a combined score based on the point values.

The present invention relates to neurological and physiological dysfunction associated with neuron disorders. In (particular, the invention relates to the involvement of vascular endothelial growth factor (VEGF) and homologues in the aetiology of motor neuron disorders. The invention further concerns a novel, mutant transgenic mouse (VEGFm / m) with a homozygous deletion in the hypoxia responsive element (HRE) of the VEGF promoter which alters the hypoxic upregulation of VEGF. These mice suffer severe adult onset muscle weakness due to progressive spinal motor neuron degeneration which is reminiscent of amyotrophic lateral sclerosis (ALS)-a fatal disorder with unknown aetiology. Furthermore, the neuropathy of these mice is not caused by vascular defects, but is due to defective VEGF-mediated survival signals to motor neurons. The present invention relates in particular to the isoform VEGF165 which stimulates survival of motor neurons via binding to neuropilin-1, a receptor known to bind semaphorin-3A which is implicated in axon retraction and neuronal death, and the VEGF Receptor-2. The present invention thus relates to the usage of VEGF, in particular VEGF165, for the treatment of neuron disorders and relates, in addition, to the usage of polymorphisms in the VEGF promotor for diagnosing the latter disorders.

Duchenne muscular dystrophy (DMD) is a progressive muscle disease that is caused by severe defects in the dystrophin gene and results in the patient's death by the third decade. The present invention utilizes the Double Mutant mice (DM) as an appropriate human model for DMD as these mice are deficient for both dystrophin and utrophin (mdx / +, utrn − / −), die at 3 months of age and suffer from severe muscle weakness, pronounced growth retardation, kyphosis, weight loss, slack posture, and immobility. Expression from a transgene of novel human retinal dystrophin Dp260 was shown to prevent premature death and reduce the severe muscular dystrophy phenotype to a mild clinical myopathy. Electromyography, histology, radiography, magnetic resonance imaging, and behavior studies concluded that DM transgenic mice grew normally, had normal spinal curvature and mobility, and had reduced muscle pathology. EMG and histologic data from transgenic DM mice showed decreased abnormalities to levels typical of mild myopathy, while the DM mice exhibited severe abnormalities commonly seen in human dystrophinopathies. The transgenic DM mice also had measurable movement levels comparable to those of untreated mdx mice and controls.

This invention relates to an effective dietary intervention plan. In one aspect all food is withheld for a period of at least 5 days, except for tropical root crops. In another aspect the invention relates to the treatment of various symptoms, conditions or diseases such as Diarrhea, constipation, congestion, eczema, asthma, fatigue, muscle weakness, tension, and spasms, irritable bowel syndrome, swelling, anxiety, multiple chemical sensitivities, moderate to extensive and moderate to severe symptoms due to food allergies, sensitivities, and intolerances, bloating, pain, headaches, leaky gut, hyperactivity, sleeping difficulties, severe underweight, eating disorders, obsessive, compulsive disorders, panic attacks, sensory sensitivities, Alzheimer's disease, acid reflux, irritability, delayed motor skills, delayed social skills, autism, PDD, infantile spasms, seizures by withholding from the patient for a period of at least 5 days all food except for concentrated forms of concentrated tropical root crops. Preferably the patient is also removed from external environmental sources of allergens. After the initial withholding period new foods may be introduced according to a particular selection and schedule. In another aspect of the invention the subject undergoes an effective dietary intervention plan in which at least five (5) tropical root crops are selected, each eaten on a successive day, along with selected other meat, vegetables, and oils that the subject has never eaten before, eating a different selection of meat, vegetables, and oils each from different food families each day, with no food or food family being repeated for at least 5 days. In another aspect the invention relates to the treatment of various symptoms, conditions or diseases such as Diarrhea, constipation, congestion, eczema, asthma, fatigue, muscle weakness, tension, and spasms, irritable bowel syndrome, swelling, anxiety, multiple chemical sensitivities, moderate to extensive and moderate to severe symptoms due to food allergies, sensitivities, and intolerances, bloating, pain, headaches, leaky gut, hyperactivity, sleeping difficulties, severe underweight, eating disorders, obsessive, compulsive disorders, panic attacks, sensory sensitivities, Alzheimer's disease, acid reflux, irritability, delayed motor skills, delayed social skills, autism, PDD, infantile spasms, seizures by withholding from the patient for a period of at least 5 days all food except for concentrated forms of concentrated tropical root crops. Preferably the patient is also removed from external environmental sources of allergens. After the initial withholding period new foods may be introduced according to a particular selection and schedule. In another aspect of the invention the subject undergoes an effective dietary intervention plan in which at least seven (7) tropical root crops are selected, each eaten on a successive day, along with selected other meat, vegetables, and oils that the subject has never eaten before, eating a different selection of meat, vegetables, and oils each from different food families each day, with no food or food family being repeated for at least 7 days. In another aspect the invention relates to the treatment of various symptoms, conditions or diseases such as Diarrhea, constipation, congestion, eczema, asthma, fatigue, muscle weakness, tension, and spasms, irritable bowel syndrome, swelling, anxiety, multiple chemical sensitivities, moderate to extensive and moderate to severe symptoms due to food allergies, sensitivities, and intolerances, bloating, pain, headaches, leaky gut, hyperactivity, sleeping difficulties, severe underweight, eating disorders, obsessive, compulsive disorders, panic attacks, sensory sensitivities, Alzheimer's disease, acid reflux, irritability, delayed motor skills, delayed social skills, autism, PDD, infantile spasms, seizures by withholding from the patient for a period of at least 5 days all food except for concentrated forms of concentrated tropical root crops. Preferably the patient is also remo

The invention discloses a health care wine for fatigue endurance and sleep regulation and a method for preparing the health care wine. The health care wine for fatigue endurance and sleep regulation is formed by brewing the following raw materials in the following proportions: 4000-8000 g of fresh grapes, 4000-8000 g of fresh mulberries, 50-100 g of astragali radix, 50-100 g of virgin soil, 20-30g of white prepared lateral root of aconite, 20-30 g of cooked rhubarb, 20-30 g of honey-fried licorice root, 300-500 g of ginger, 100-200 g of sweet osmanthus, 9-15 g of notopterygium root, 1000-3000 g of Chinese date, 2000-3000 g of lily, 2000-4000 g of fushen, 20-30 g of amomum cardamomum and 60-100 L of white spirit. The health care wine is capable of enduring fatigue, regulating sleep, recuperating liver and kidney, settling the viscera and enhancing the disease resistance of a human body, and has a good regulation effect for laziness, fatigue, insomnia and dreaminess, soreness and weakness of waist and knees, muscle weakness, hyposexuality, hair loss and the like caused by life stress.

The invention relates to the technical field of chairs for old people, in particular to a chair for old people and convenient to get up. The chair for old people and convenient to get up comprises a supporting seat; the top of the supporting seat is fixedly connected with handrails; the side surface of the supporting seat is fixedly connected with a backrest; the bottom of an inner cavity of the supporting seat is fixedly connected with a hip thrust mechanism; and the hip thrust mechanism is in transmission connection with an arm supporting mechanism. The chair for old people and convenient toget up is particularly suitable for old people who are physically challenged and have muscle weakness to use; and when the old people need to get up from the chair, the hip of the old people can be pushed by pressing a switch seat body on the chair, the arms of the old people can be supported, the supporting and assisting effect is achieved, and the old people can get up from the chair conveniently. According to the chair, the old people can get up from the chair without being assisted when getting up, and the switch can be controlled to stop at any time or an assistant mode is started, so that the chair has the following advantages: the old people can get up conveniently; and when the old people need to sit down, the old people can sit on the chair conveniently.

An ankle foot orthosis that may be used for children with lower extremity spasticity or muscle weakness to prevent deformity and enhance extremity function. The orthosis includes an adjustable tension assembly connected to an upper leg portion and a lower foot portion. The tension assembly includes a tension adjuster connected with an elastomer band, with the tension adjuster being operable to selectively increase or decrease the amount of stretch applied to the elastomer band to provide a selectable upward biasing force to a patient's foot. The dynamic orthosis creates a variable load stretch below the knee preventing muscle contracture, heel cord shortening, and increases range of motion and is utilized during rest, sleep, and short distant weight bearing providing readings of the range of motion continuously. The orthosis incorporates a circumferential dynamic support system that maintains corrected alignment of the bones of the foot and ankle.

A method for preparation pharmaceutical compounds in large quantities consists of copper (I) halide, preferably the chloride complex of nicotinic acid characterized by elemental analysis, spectroscopy and crystallographic methods, used for treatment of muscular dystrophy, myopathy, myasthenia gravis, parkinsonism, Chronic Fatigue Syndrome, Male Infertility and post stroke muscle weakness.Chlorobis (nicotinic acid) copper (I) monohydrate complex, its composition [CuCl (nicotinic acid)2]. H2O, has been prepared and its physical and chemical properties as well as its crystal structure have been investigated for the first time.

The invention discloses a vertical and horizontal dual-purpose mouse. The vertical and horizontal dual-purpose mouse comprises a mouse body and a base. The mouse body comprises a left key, a right key and a roller. The left key, the right key and the roller are located at the top of the mouse body. The bottom of the mouse body is hinged to the base. The base is provided with a laser transmitter. The laser transmitter is electrically connected with the left key, the right key and the roller. The vertical and horizontal dual-purpose mouse has the advantages that the vertical and horizontal dual-purpose mouse can be used selectively in a horizontal mode or a vertical mode, the use flexibility of the mouse is improved, and the symptoms such as thickening of the tendon in the carpal canal, space constriction of the carpal canal, pain and numbness of the fingers, muscle weakness and the like caused by the fact that a mouse is used by people through one posture for a long time are reduced. When the vertical and horizontal dual-purpose mouse is used, the hand can be parallel to the front arm, thus, when the mouse is moved, people frequently move the arm, frequent motion of the wrist is reduced, and the wrist is in a natural state.

The present invention relates to a treatment of muscle weakness resulting from a disease state or injury in a subject suffering therefrom by administering a composition including histamine in an amount effective to alleviate muscle weakness in the subject suffering therefrom.

The present invention provides an amino acid beverage, which has effects of high protein, easy absorption, human body development promoting, immune function enhancing, liver function enhancing, fatigue eliminating, balanced nutrition, rapid body force supplementing and fatigue relieving; in the formula, the amino acids synergistically work to promote normal body growth, repair tissue, regulate blood sugar, and provide required energy; when people participates in intense physical activity, the beverage can provide additional energy for muscle so as to produce glucose to prevent muscle weakness; and the technical scheme comprises that the amino acid beverage comprises 0.1% of lysine, 0.1% of taurine, 0.1% of arginine, 0.05% of aspartic acid, 0.03% of valine, 0.03% of leucine, 0.025% of glutamic acid, 0.025% of isoleucine, 1% of xylitol, 0.5% of citric acid, 1% of oligoisomaltose, 0.05% of acesulfame, and the balance of purified water.

A portable electrical motor-driven exoskeleton ankle joint robot with gear transmission and control system which is intended to provide walking assistance in different speed and walking conditions to persons with disability in walking or muscle weakness or joint problem.

The invention discloses a blood-activating, pain-relieving and bone-strengthening ointment, which is an external ointment. The blood-activating, pain-relieving and bone-strengthening ointment is prepared from saffron, dragon's blood, long-noded pit viper, gastrodia elata, musk tibetene, menthol, borneol, and has the effects of relaxing muscles and stimulating blood circulation, relieving swelling and pains, removing stasis and mass, reunioning fractured tendons and bones, dispelling wind and eliminating dampness, warming and activating meridian, removing necrotic tissue and promoting granulation and the like. The ointment can be widely applied to the surgical department, the pediatrics department, the gynecology department and other clinical departments, can be used for treating sore pain, burning pain, sciatica, arthralgia caused by hyperosteogeny, lumbar muscle strain, oil injury of bone fracture, bone spur, arthritis, aged rheumatism, rheumatoid arthritis, lumbar disc herniation, periostitis, bone tuberculosis, osteomyelitis, tenosynovitis, ankylosing spondylitis, scapulohumeral periarthritis, spinal stenosis, mid-early femoral head necrosis, soft tissue injury or cartilage wear, or clinical common pain symptoms caused by deformed joints, muscle weakness, numb, stiffness, muscle paralysis, atrophy and other reasons.

The invention provides a medical rehabilitation care bed which comprises a bed body which comprises a bed frame and a bed board. Two sides of the upper portion of the bed frame are provided with sliding grooves, and strip-shaped sliding blocks are arranged on the two sides of the lower surface of the bed board corresponding to the sliding grooves. The bed body comprises a front board and a rear board, the front board is hinged to the rear board, the end of the front board is provided with a height adjusting mechanism connected with the bed frame, the bed frame is provided with a modular massage mechanism through a translation mechanism, the side of the bed frame is provided with a box body, a medicine smearing mechanism is movably arranged in the box body, the bed frame is provided with amedicine liquid drying mechanism, a rehabilitation box is further arranged below the bed frame, and a moxa steaming mechanism is arranged in the rehabilitation box. The medical rehabilitation care bedcan perform rehabilitation nursing on a patient, massage legs of the patient and keep blood smooth, and medicines can be smeared to the body of the patient, and absorption is promoted through heating. The patient's muscle weakness caused by lying in bed for a long time is alleviated through moxa thermotherapy, adjuvant treatment of diseases is performed, and patient's recovery speed is greatly accelerated.

The invention provides a wearable U-shaped limb power-assisted airbag and a manufacturing method thereof, belonging to the technical field of robots for the disabled and the elderly. The U-shaped limb power-assisted airbag is worn on a human joint, supplies assistance to the human joint through controlling the air pressure in the airbag, and is applicable to a patient who difficultly moves resulting from muscle weakness. The U-shaped airbag comprises a plastic U-shaped airbag body, an airbag fixing strap and an air nozzle and is made by a heat-seal connection technology. The wearable U-shaped limb power-assisted airbag is fixed by threading an elastic band through a fixing sleeve and a magic tape sewn on clothes while wearing. When the wearable U-shaped limb power-assisted airbag is worn in different parts, pneumatic assistance of six actions, namely flexion / extension of shoulder joints, expansion / contraction of shoulder joints, flexion / extension of elbow joints, inward rotation / outward rotation of elbow joints, flexion / extension of knee joints and flexion / extension of the waist in total can be realized.

The invention discloses a pharmaceutical composition containing sodium vitamin C and a preparation method thereof. The pharmaceutical composition contains the following components in parts by weight: 75-95 parts of sodium vitamin C, 5-10 parts of potassium chloride, pharmaceutically acceptable 0‑10 parts of accessories. The present invention overcomes the disadvantages of existing vitamin C such as high acidity and easy oxidation, and solves the clinical problem that potassium chloride produced by the combination of vitamin C and potassium chloride accelerates the oxidation of vitamin C, etc., so that the product has better stability and more definite curative effect It is suitable for patients who lack vitamin C and potassium in clinic. It can be used to treat scurvy, infectious diseases, purpura and other diseases with muscle weakness, paralysis, arrhythmia or renal dysfunction. It can also be used for malignant tumors, heart and brain. Prevention and adjuvant treatment of vascular diseases, infectious diseases, autoimmune diseases and other major difficult diseases.

The invention provides a double-handle pull-down trainer comprising a vertical frame; a training guideline panel is arranged on the vertical frame; an upper fixing frame and a lower fixing frame are mounted on the upper part and the lower part of the vertical frame respectively; a sliding rod is mounted on the upper fixing frame; the sliding rod penetrates through an enclosed counterweight barreland then is vertically mounted on the lower fixing frame; the enclosed counterweight barrel can move up and down along the sliding rod; the two sides of the enclosed counterweight barrel are providedwith connection blocks; the connection blocks are hinged to the enclosed counterweight barrel; the connection blocks are connected with loop chains; and the other end of each loop chain is connected with a pull handle. According to the double-handle pull-down trainer in the invention, counterweights on the fixed sliding rod are pulled by a human body for safely training leg muscle groups, arm muscle groups and back muscle groups, enhancing the cardiopulmonary function, improving the body flexibility and the coordination ability, improving the joint stability and realizing the rehabilitation effect on movement disorder, muscle weakness, muscle atrophy and other symptoms; and training personnel are helped to take exercise scientifically through a touch screen display according to the conditions of the training personnel, the fitness effect is displayed, and intelligent broadcast is carried out through voice.

Novel methods for prevention, reduction or elimination of the incidence of male androgen deficiency symptoms or diseases including male hypogonadism-associated symptoms and diseases associated with low serum testosterone and / or low DHEA or low total androgens in susceptible warm-blooded animals including humans involving administration of an amount of a sex steroid precursor, particularly dehydroepiandrosterone (DHEA) and a selective estrogen receptor modulator (SERM) (particularly acolbifene), an antiestrogen or a prodrug of the two. The symptoms or diseases are loss of libido, erectile dysfunction, tiredness, loss of energy, depression, bone loss, muscle loss, muscle weakness, fat accumulation, memory loss, cognition loss, Alzheimer's disease, dementia, loss of body hair, fertility problems, insomnia, gynecomastia, anemia, hot flushes, sweats, decreased sense of well-being, obesity, osteoporosis, hypercholesterolemia, hyperlipidemia, atherosclerosis, hypertension, insulin resistance, cardiovascular disease and type 2 diabetes. Pharmaceutical compositions for delivery of active ingredient(s) and kit(s) useful to the invention are also disclosed.