1869 results about "Injury cause" patented technology

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prefabricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. A plurality of anchoring elements may share a single upper layer.

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prefabricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. A plurality of anchoring elements may share a single upper layer.

A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease is disclosed. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prebricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. Additionally, ridges may be formed about the periphery of each plug to facilitate its anchoring to surrounding cartilage, bone and / or adjacent plugs. A procedure for resecting damaged or diseased cartilage and for implanting a replacement plug or plugs according to this invention, as well as a set of instruments for effecting the procedure, and a self-contained system for orthopedic surgeons, which includes a variety of differently sized and shaped plugs, as well as a set of instruments for the procedure are also disclosed.< / PTEXT>

Devices and methods are disclosed for achieving chest drainage in humans or other animals. Chest drainage is often required following traumatic injury or surgery. The devices and methods disclosed herein are especially useful in the emergency, trauma surgery or military setting. The devices utilize a chest tube with a cutting distal end and a central blunt trocar. The blunt trocar or obturator shields the sharp cutting distal end of the chest tube until controllably retracted. Once the blunt trocar or obturator is retracted, the chest tube is advanced out through its sterile, protective package and into the patient. The blunt trocar is advanced back into its position to shield the sharp tip of the chest tube during patient insertion. The chest tube also includes a hold-down mechanism that is created by an adhesive seal to the patient's chest and ribbons or straps that are wrapped around the chest tube once it is correctly positioned. The straps include adhesive ends to grip the chest tube once the straps are in place.

The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.

The invention relates to a Chinese medicinal preparation for treating bone fracture, which is prepared from 84 raw medicinal materials such as radix astragali, Chinese angelica, rehmanniae vaporata, rehmanniae praeparatum, suberect spatholobus stem, human placenta and the like. The medicament can be made into an oral preparation and external application preparation. A preparation method comprises the following steps: preparing an aqueous extract of the raw medicinal materials, and preparing an oral solution and a spraying agent from the aqueous extract; and preparing extracting pulvis from the aqueous extract, and preparing granules, pills, medicinal granules, tablets or capsules from the extracting pulvis. Raw medicinal powder also can be ground into raw powder pulvis which can be prepared into the granules, the pills, the medicinal granules, the tablets or the capsules, or the raw powder pulvis is prepared into external application ointment. In addition, the raw medicinal materials also can be infused to form medicinal liquor. The Chinese medicinal preparation has good curative effect on bone fracture diseases of different types, is mainly used for treating different types of fracture, muscles and bones breakage, traumatic injury, new and old incised wound and gunshot wound, bleeding and blood stasis which are caused by traumatism and other symptoms, and has the obvious curative effect on rheumatoid arthritis. The Chinese medicinal preparation is prepared from pure Chinese medicaments, and has convenient use, safety, reliability, no toxic or side effect and long-term use.

Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of cartilage and bone damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).

An improved health and safety system for a table saw includes one or more of: a blade guard that protects the operator from the saw blade, and contains and collects sawdust; a proximity detector and emergency saw motor braking means for use in connection with such blade guard; an anti-kickback device for use in connection with such blade guard, a rip fence adapter for use in connection with such a blade guard, and hoses and fittings to connect the dust containment and collection system of said blade guard to a shop dust collection blower or vacuum system. The system protects the saw operator from potential traumatic injury to a hand, and from ingesting potentially carcinogenic sawdust.

This invention relates to cannabinoid-containing compositions, particularly cannabinoid-containing gel formulations and methods for the treatment of traumatic injury, e.g., strains, sprains and contusions, and disease conditions, e.g., arthritis, particularly osteoarthritis. The methods involve topically applying a cannabinoid or a cannabinoid-containing composition to a subject's skin near, or distant from, the area of the injury or the area affected by the disease condition, e.g., an arthritic joint. The cannabinoid-containing composition is preferably a pharmaceutically acceptable gel containing a therapeutically effective amount of a cannabinoid sufficient to alleviate the symptoms associate with the injury or disease condition.

This invention relates to methods of screening for modulators of mammalian cell injury cause by TRPM7 gene and protein activity, compounds that modulate TRPM7 gene and protein activity and methods of treatment of mammalian cell injury using modulators of TRPM7 gene and protein activity.

The present invention relates to the storage agent for preservation of an animal cell or organ and preserved process. Ordinary method of cell storage is employed preserving method by freezing at extra low temperature of -196° C. and the survival ratios of cells after thawing and fusion is low, about 10 to 30%. The period of validity is a very short time of 12 to 72 hours. The storage agent can make protein stabilize to protein type storage agent, and prevent, treat and improve organ injury caused on an organ transplant operation by adding the polyphenol.

The invention discloses a pharmaceutical composition with effects of promoting blood circulation by removing blood stasis, anti-inflammatory and detumescence, and relieving pain and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials: 20-100 parts by mass of rhubarb, 20-110 parts by mass of gardenia and 10-100 parts by mass of baikal skullcap root. The preparation method of the pharmaceutical composition comprises the following steps: extracting the raw materials with water or ethanol for preparing the pharmaceutical composition, and then filtering and collecting filtrate to obtain the pharmaceutical composition. Clinical trials show that the pharmaceutical composition has favorable curative effect of relieving pains in neck and shoulders, waist and legs, joints and muscles caused by rheumatism, hyperosteogeny, traumatic injury, and the like.

The invention discloses detumescent and analgesic ointment for curing rheumatism and contusion and a preparation method thereof. The ointment is a pure herbal pharmaceutics, which is composed of monarch drugs, ministerial drugs, adjuvant drugs and conductant drugs. The preparation method comprises the following steps: placing 5kg of tung oil in a pan; grinding all traditional Chinese bug bulk pharmaceutical chemicals (BPC) into refined powder, wrapping the adjuvant drugs and the conductant drugs with gauzes, and placing into a frying pan for boiling; boiling with charcoal fire for 90min, putting the powder in to the frying pan after generating smokes, and boiling the mixture to obtain semi-creamy mixture; placing the ministerial drugs into the pan for even stirring to obtain semi-creamy mixture; taking the pan away from the fire and putting the monarch drugs into ointment for even stirring; placing 2.5kg of rosin into the ointment and evenly stirring to obtain the ointment, and pasting the ointment on kraft papers with 11 centimeters; and pressing the ointment on the kraft papers by a 6-centimeter iron module to obtain the ointment with diameter of 6 centimeters, and placing the obtained ointment on fixed patches. The detumescent and analgesic ointment for curing rheumatism and contusion can be used for stimulating the circulation of the blood and causing the muscles and joints to relax, relieving bruises and pains, and curing traumatic injuries and rheumatoid arthritis.

A fixator for use in the reconstruction of acute, chronic and traumatic injuries to the upper and lower extremities. The fixator has a unique clamping system that allows for the snapping in of pins and rails, and for multi-planar fixation of bones.

Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be in a liquid, gel, paste, foam, or another form. Uses may include treating a traumatic injury such as in injury caused by a bullet, an explosive, a blade etc., or an injury caused during a medical procedure such as surgery.

The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.

An improved design for a helmet to reduce injuries caused by helmet-to-helmet collisions. Certain embodiments include novel quick release features that permit the detachment of a facemask from a helmet in 30 seconds or less, resulting in the ability to attend to an injured player in a rapid fashion and without the need for any additional tools to accomplish such removal. Other aspects relate to impact energy absorbing constructions, including shock absorbing systems and PEEK facemask designs, that when combined with the quick release features described, provide a superior helmet for a player's protection.

The present invention provides compositions and methods for the treatment of central nervous system damage in a subject. More particularly, the invention provides a combination therapy for the treatment of a central nervous system ischemic condition or a central nervous system traumatic injury comprising the administration to a subject of a potassium ion channel modulator in combination with a cyclooxygenase-2 selective inhibitor.

The invention belongs to the field of medical devices, and in particular to a great vascular stent delivery system capable of realizing a front-end back release function. The great vascular stent delivery system is composed of a locating guide head, a back release mechanism, a core tube, a middle tube, a sheath tube, a big handle, a small handle and a push rod which are sequentially arranged fromfront to back. The whole system has the advantage of simple mechanism, is convenient in operation and safe in use and is capable of effectively avoiding the phenomena of release in advance and failure in release; and meanwhile the stainless steel core tube is locally engraved into a spring, thus achieving the purposes of reducing core tube diameter and system size, greatly improving flexibility of the far end of the system, and reducing vascular injury caused by the system during the delivery process.

The present invention features the use of selected complement activation inhibitor(s) for treating an individual who has suffered a severe injury. The complement activation inhibitor acts at or above the level of C3 activation and does not significantly deplete or irreversibly inhibit complement activation. Also provided are compositions and methods for repleting and / or enhancing complement activation capacity in a subject who has suffered a traumatic injury.

The present invention discloses a method for the occlusion of blood vessels or fluid vessels to stop the flow of blood or fluid during elective or emergency surgical procedures or following traumatic injury. This invention also encompasses a medical device or tool for occluding, reducing, or controlling blood flow or fluid flow. In this invention, a plug or blockade is formed to occlude, reduce, or control blood flow or fluid flow when magnetic microparticles, nanoparticles, or colloids are administered into a blood vessel or fluid vessel, and an external magnetic field source is placed at the desired site near or above the path of the blood stream or fluid flow. Removal of said external magnetic field source would result in the redispersion of the microparticle blockade and resumption of the flow.

An improved health and safety system for a table saw includes one or more of: a blade guard that protects the operator from the saw blade, and contains and collects sawdust; a proximity detector and emergency saw motor braking means for use in connection with such blade guard; an anti-kickback device for use in connection with such blade guard, a rip fence adapter for use in connection with such a blade guard, and hoses and fittings to connect the dust containment and collection system of said blade guard to a shop dust collection blower or vacuum system. The system protects the saw operator from potential traumatic injury to a hand, and from ingesting potentially carcinogenic sawdust.

The present invention provides a composition, and a method of use thereof for treating connective tissue damage in man and in animals, which comprises a therapeutically effective amount of chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan (hyaluronic acid). Particularly, the present invention provides a composition, and a method of use thereof, for treating connective tissue damage including, but not limited to, arthritic disease, osteoarthritis, rheumatoid arthritis, osterochondrosis dessicans, cartilage damage, joint injury, joint inflammation, joint synovitis, degenerative joint disease (DJD), post surgical DJD, traumatic injury, fracture, tendon damage, ligament damage, skeletal damage, musculoskeletal damage, fiber damage, adipose tissue damage, blood cell damage, and plasma damage. Compositions for delivery of the present invention include those for parenteral, oral, and transmucosal delivery and for direct surgical placement onto the affected tissues.

A method of producing a homogenous population of homozygous stem (HS) cells pre-selected for immunotype and / or genotype from donor cells is described herein. The invention relates to methods of using immunohistocompatible HS cells for diagnosis, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, traumatic injuries and cancer. The invention further relates to methods for using histocompatible HS stem cells pre-selected for a non-disease genotype for prophylactic and therapeutic intervention including, but not limited to, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, and cancer. Furthermore, the invention relates to a catalogued transplant depository of HS cells derived from multiple donors, each of the HS cells being homozygous for a unique HLA haplotype, for the purpose of having a constant, reliable, comprehensive supply of immunohistocompatible cells for diagnosis, treatment and / or transplantation.

Some embodiments of the invention provide an apparatus for achieving hemostasis in a puncture tract. Such a tract might have been created during a medical procedure, operation or a traumatic injury. In some embodiments, the apparatus includes a bandage for placement within the puncture tract. The apparatus also includes a stem with a distal end. In some embodiments, the bandage couples to the distal end of the stem. In other embodiments, the bandage couples to the entire length of the stem. Along with the bandage, the stem's distal end is at least partially inserted into the puncture tract in some embodiments. In other embodiments, only the bandage is inserted into the puncture tract. The bandage is typically maintained within the puncture tract until hemostasis is achieved. Once hemostasis has been achieved, the operator removes the bandage from the puncture tract.

The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and / or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.

The invention relates to an anti-explosion shower head. The problem of burst of shower heads caused by the facts that water spraying holes become small or are blocked or water pressure rises abnormally is solved. According to the technical scheme, an anti-explosion valve is positioned in a shower head disc. The anti-explosion valve can be automatically opened or closed along with the changes of water pressure in the shower head, so as to achieve the effect of adjusting the water pressure in the shower head. The anti-explosion shower head can avoid users' personal injury caused by shower head burst caused by too high water pressure in the shower head.