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An optical-signal vestibular-nerve stimulation device and method that provides different nerve stimulation signals to a plurality of different vestibular nerves, including at least some of the three semicircular canal nerves and the two otolith organ nerves. In some embodiments, balance conditions of the person are sensed by the implanted device, and based on the sensed balance conditions, varying infrared (IR) nerve-stimulation signals are sent to a plurality of the different vestibular nerves.

The invention discloses traditional Chinese medicine liquor for treating arthritis. The traditional Chinese medicine liquor is mainly prepared from raw dog bones, radix rehmanniae, angelica, rhizoma ligustici wallichii, sheep fat prepared herba epimedii, wine prepared radices paeoniae alba, cornua cervi pantotrichum, white wine, sugar candy, white sugar and other raw materials by a medicine liquor preparation method. With the compatibility of the raw material medicines, the traditional Chinese medicine liquor has the efficacies of expelling wind, eliminating dampness, dredging meridian passage, strengthening tendons and bones, replenishing qi, invigorating spleen, warming kidney, removing paralysis and relieving pain, and is suitable for rheumatoid arthritis and arthritis of other properties.

The invention discloses a livestock and poultry anti-diarrheal feed additive and a preparation method thereof. In a technical scheme, the preparation method comprises the following steps of: smashing India quassiawood, dried ginger, licorice, costus root and the like; screening through a sieve; adding bean pulp, corn starch, bran and water to prepare a fermentation medium; adjusting the pH value,sterilizing, cooling, and inoculating for fermenting; and drying after the fermentation is finished to obtain the livestock and poultry anti-diarrheal feed additive. The livestock and poultry anti-diarrheal feed additive disclosed by the invention has the better functions of broad-spectrum bacterium resistance, virus resistance, parasite resistance, maintaining of the balance of microbial flora in the animal bodies, and can be used for effectively reducing the incidence of diarrheal of the livestock and poultry, promoting the growth of the livestock and poultry and reducing the cultivation investment; and the livestock and poultry anti-diarrheal feed additive has the characteristics of no toxic and side effects, no pollution, no residue, stable and reliable effect and the like, cannot give rise to drug tolerance, and can meet the requirement of people on safety production of the livestock and poultry products. The livestock and poultry anti-diarrheal feed additive disclosed by the invention also can be used as a veterinary drug in an increased dose manner, and has a remarkable curative effect for treating the diarrheal caused by various viruses, bacteria and parasitic infection for the livestock and poultry.

The invention relates to a multi-effect external plaster and belongs to the field of external traditional Chinese medicines. The multi-effect external plaster is characterized by consisting of components A and B, wherein the component A comprises more than sixty Chinese herbs such as Chinese angelica, white paeony root, peach seed, beautiful sweetgum fruit, Indian iphigenia bulb, common selfheal fruit-spike, European verbena, twotooth achyranthes root, eucommia bark, centipede and the like, colophony, yellow lead and sesame oil; and the component B mainly comprises more than ten Chinese herbal medicinal ingredients such as white pepper, safflower, white mustard seed, medcinal evodia fruit, pyrite, dragon's blood, menthol, azone and the like, superfine natural magnetite powder and infrared ceramic powder. By combining the components A and B, the plaster of the invention not only has treatment effectiveness of the traditional plaster, but also has physiotherapy effectiveness of infrared rays, magnet therapy and the like. The multi-effect external plaster is suitable for various symptoms, such as traumatic injury, cervical spondylosis, spinal stenosis, scapulohumeral periarthritis, protrusion of lumbar vertebral disc, sciatica, lumbar muscle strain, arthritis, paraesthesia, facial nerve paralysis, facial nerve spasm, irregular menstruation and the like.

The invention provides a gene construct encoding a cell targeting moiety and a heterologous prodrug activating enzyme for use as a medicament in a mammalian host wherein the gene construct is capable of expressing the cell targeting moiety and enzyme as a conjugate within a target cell in the mammalian host and wherein the conjugate is directed to leave the cell thereafter for selective localisation at a cell surface antigen recognised by the cell targeting moiety.

The invention relates to a chitosan nano silver gelata used for treating an inflammation in a lower genital tract, cervicitis and cervical erosion of female and empyrosis, scalding, bedsore infection and other skin inflammations such as tinea manus and pedes, and various wound infections, etc. The medicinal raw materials of the chitosan nano silver gelata of the invention are the nano silver and chitosan polymer in respective therapy dose; the nano silver is the nano silver powder or the nano silver colloid; the chitosan polymer is the chitosan and the chitin and one or more than one derivative of the chitosan and the chitin. The product of the invention has the advantages of high efficiency and being nonpoisonous, and has an extremely strong antibacterial action and an excellent therapeutic effect; compared with other nano silver gelata, the chitosan nano silver gelata of the invention has the advantages of perfect sterilizing effect, long-lasting effect and tissue repair function.

The invention discloses a dug for treating rheumatism and rheumatoid disease, which is a pharmaceutical composition prepared by selecting purely natural plants and animals as raw material according to a certain process. The dug for treating rheumatism and rheumatoid disease has the advantages of wide range of raw material sources and low cost; in addition, the preparation method of the pharmaceutical composition is simple.

The present invention discloses a prescription for treating gastropathy, pertaining to a Chinese medicine. The recipe includes 10 chunhua, 10 finger citron flower, 10 official magnolia flower, 10 green tangerine peel, 10 zhixiangfu, 10 heterophylly falsestarwort root, 15 fried largehead atractylode with earth, 6 prepared pinellia tuber, 12 white poria, 10 dried citrus peel, 6 liquorice, 10 gongying, 12 bullbrier, 10 lobed kudzuvine, 10 hovenia dulcis, 15 parched Chinese radish seed, 10 glabrous greenbrier rhizome, 12 white peony root, 10 Chinese angelica root, 15 radix adenophorae, 12 dwarf lilyturf , 10 nobile dendrobium, 6 bamboo shavings, 10 virgate wormwood herb, 6 bupleurum falcatum, 6 parched gentian with wine, 10 ground ivy, 6 jinlingzi, 10 xuanhusuo, 6 betelnut, 10 zhichuanjun, 15 chicken's gizzard skin, 15 fried barley sprout and 10 citrus medica, as well as three pieces of gingers and four jujubes as pharmacal. The prescription has good curative effect on superficial gastritis, atrophic gastritis, erosive gastritis, hypertrophic gastritis, bile reflux gastritis and gastric ulcer.

The invention discloses a medicinal composition for treating skin injury and ulcer diseases, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and Chinesemedicaments for fighting bacterium, diminishing inflammation, removing putrefaction and promoting tissue regeneration such as angelica, Szechuan lovage rhizome, salvia root and the like which are prepared into a plurality of dosage forms by matching the prior art. The technology overcomes the defects that the prior preparations for the trauma department have extremely slow response, longer treatment course, adhesion with the skin, influence on scab cicatrization and the like, and has quick and remarkable treatment effect on various skin diabrosis diseases such as mechanical wound, burn / scald,bedsore, chronic leg ulcer, diabetic foot or cancerous ulcer and the like.

The invention relates to toothpaste including radix notoginseng and propolis and a preparation method thereof. The toothpaste comprises the following raw materials according to percentage by weight: 0.1-1.5% of radix notoginseng extract, 0.03-3.2% of propolis powder, 25-46% of natural calcium carbonate, 5-15% of silica, 3-20% of glycerol, -4001-10% of polyethylene glycol, 0.2-1.0% of sodium pyrophosphate, 0.2-1.5% of xanthan gum, 0.1-1.5% of carboxymethyl cellulose, 3-25% of sorbic alcohol, 0.1-1% of saccharin sodium salt, 1-5% of lauryl sodium sulphate, 0.05-0.5% of sodium ethyl p-hydroxybenzoate, 0.02-2% of sodium propylparaben, 0.3-3% of essence, 0.01-0.3% of triclosan, 0.05-2% of zinc citrate, and the balance of water. The natural nursing toothpaste including the radix notoginseng extract has obvious curative effects on gingivitis, bleeding gums, dental ulcer and the like. The propolis has the functions of diminishing inflammation, easing pain and stopping bleeding. The radix notoginseng and the propolis are used in the toothpaste at the same time so that the toothpaste has more obvious effects for stopping pain and resisting gingivitis, bleeding gums and pain.

Devices and methods of treatment of tissue, such as skin tissue, with electromagnetic radiation (EMR) are disclosed that employ local deformation of tissue in small areas. Devices and methods employing local deformation are used to produce fractional lattices of EMR-treated islets in tissue.

Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other medication, and to combination products and compositions comprising the formulations and at least one other medication, such as neuroleptic (antipsychotic) and / or antidepressant drugs.

[Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a water-solubility.[Means for Solving Problems] Disclosed is a polymer conjugate of a taxane, which comprises a polymer having a polyethylene glycol moiety and two or more succinic acid monoamide moieties and a taxane, wherein a carboxylate group in the polymer and an alcoholic hydroxyl group in the taxane are bound to each other via an ester bonding.

The invention discloses a new traditional Chinese medicine composition for treating constipation and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following bulk pharmaceutical chemicals: odoratum, dendrobium, Chinese bushcherry seed, hemp seed, angelica, raw astragalus, codonopsis, Chinese yam, picrorhiza, starwort, root-bark of Chinese wolfberry, gypsum, anemarrhena, rhizoma imperatae, puerarin, scrophulariaceae, rehmanniae, motherwort, fleece-flower root, white peony root, the root of straight ladybell, wolfberry fruit, lucid asparagus, the root of Chinese trichosanthes, liriope, glassleaved sweetflag rhizome, prepared rhubarb, radish seed and the like. The traditional Chinese medicine composition in the invention can be prepared into any common oral preparation in the conventional preparation method of traditional Chinese medicine. The traditional Chinese medicine composition can obviously improve the symptoms of constipation, dry stool, difficult ejectment, abdominal distension, stomachache, anorexia, heating regurgitation, defecating with blood and the like, has the advantages of exact clinical effect, obvious effect, rapid effect taking and also has the advantages of low cost, basically no toxic and side effect and the like.

The invention discloses the use of ursane type triterpenoid saponin in preparing medicine for increasing leucocyte and / or platelet which has a general formula (I), the invention also provides a pharmaceutical composition having the action of increasing human leucocyte and / or platelet, which contains ursane type triterpenoid saponin composition having a general formula (I), and pharmaceutically acceptable salts.

A method of producing a healthcare yang-invigorating preparation for males is provided. The method is characterized in that: male silkworm pupa-cordyceps militaris-oyster peptides prepared by subjecting raw materials including male silkworm pupae, cordyceps militaris (L.) Link and oyster to enzymolysis, a composite extract prepared from mulberry fruit, barbary wolfberry fruit, palmleaf raspberry fruit, solomonseal rhizome, common yam rhizome, gordon euryale seed, poria, jujube kernels, cortex cinnamomi, Chinese date and ginseng and broken pine pollen prepared from pine pollen are added and fully mixed, an excipient is added into the mixture and the mixture is prepared into granules, capsules, and a tablet candy preparation according to conventional preparing processes. Compatibility of components adopted is scientific. An adopted preparing process is unique and simple. According to the method and the preparation, a production process is simple, the preparation is simple to eat, has effects of tonifying the kidney and qi, tonifying the lung and kidney, promoting sperm production, boosting marrow, invigorating the spleen and the stomach, improving microcirculation of human bodies, eliminating moisture, removing paralysis, boosting immunity, preventing fatigue, resisting viruses, strengthening bodies, invigorating yang and treating impotence, has obvious curative effects, mild functions and no side or toxic effects, and is an ideal healthcare yang-invigorating preparation for males.

The invention relates to a medicament for treating fractures and a preparation method thereof. The medicament comprises a bone-knitting plaster, a bone-knitting powder and a bone-knitting capsule, wherein the bone-knitting plaster comprises frankincense, myrrh, radix clematidis, red-rooted salvia roots, sesame oil, yellow lead, and the like; the bone-knitting powder comprises raidx astragali, Chinese angelica, licorice roots, Xueye, and the like; and the bone-knitting capsule comprises radix bupleuri, red peony, dipsacus asperoides, peach kernels, and the like. When in use, the bone-knitting plaster is used together with the bone-knitting powder or the bone-knitting capsule. The medicament can effectively treat fractures, bone joint dislocations, intervertebral disc protrusions and hyperosteogeny and have obvious treatment effect and high cure rate on symptoms such as delayedunions, nonunions, and the like. The medicament has no toxic or side effects, can be taken by both adults and children, is simple and convenient to operate and use, can be widely applied to various types of fractures and external wounds of different parts at different ages and is popular for patients.

The present invention relates to a functional combination preparation comprising a dihydropyridine-based calcium channel blocker such as amlodipine and an ARB (Angiotensin-2 receptor blocker) such as losartan. In particular, the present invention relates to a chronotherapeutical combination pharmaceutical formulations with controlled-release for the prevention or treatment of cardiovascular disease, which is formulated in accordance with xenobiotics and chronotherapy for enabling the two drugs to be chronotherapeutically released, thereby improving the therapeutic activity as compared to the co-administration of each drug in the form of a single pill, while reducing side effects and maintaining the therapeutic activity as high as possible at the time of day when the risk of a complication of cardiovascular disease is highest.

A Chinese medicine in the form of plaster for treating rheumatic arthritis, hyperosteogeny, cervical spondylopathy, lumbar intervertebral disk protrusion, and muscle and bone injury is prepared from 56 Chinese-medicinal materials including camphor, pinellia tuber, hot pepper, toad venom, etc. Its advantage is high curative effect.

The invention provides a traditional Chinese medicinal composition for reducing blood sugar and blood pressure and a preparation method thereof. The traditional Chinese medicinal composition comprises ginseng, glossy ganoderma, yam, acanthopanax bark, astragalus, largehead atractylodes rhizome, medlar, solomonseal rhizome, sea horse, atractylodes rhizome, pseudo-ginseng, kudzuvine root, goldthread, prepared rehmannia root, fragrant solomonseal rhizome, dendrobium, dwarf lilyturf tuber, tuber fleeceflower root, poria, anemarrhena, tall gastrodia tuber, Chinese magnoliavine fruit, epimedium, bee glue, mulberry leaves and other traditional Chinese medicinal materials; and the traditional Chinese medicinal composition can be prepared into various formulations through operable processes. The traditional Chinese medicinal composition has the curative effects of strengthening spleen and nourishing yin, benefiting qi and nourishing blood, reducing blood sugar and blood pressure, improving immunity and the like, is simple in process and low in cost, and is suitable for medicating diabetes and hypertension patients, particularly middle aged and old people.

A breviscapine-phosphotide composition in the form of oral preparation or injection is prepared from breviscapine and soybean (or egg yolk, or synthetic) lecithine in a wt ratio of 1:(0.5-50) through heating, reflux, washing and drying. Its advantages are high stability and durability, and quickly taking its curative effect.

A Chinese medicine for treating diabetic retinopathy is prepared from 12 Chinese-medicinal materials including red peony root, astragalus root, rehmannia root, rhubarb, notoginseng, etc.

The invention relates to a traditional Chinese medicine composition for treating burn, comprising an oral medicine and an externally applied medicine, wherein the oral medicine is prepared from angelica sinensis, hemlock parsley, astragali, pseudo-ginseng, sanguisorba, safflower, radix rehmanniae, spatholobus stem, baikal skullcap root, giant knotweed, oldenlandia diffusa, dangshen, tuckahoe, white atractylodes rhizome and red peony root; and the externally applied medicine is prepared from myrrh, mastic, rhubarb, pseudo-ginseng, safflower, draconis sanguis, natural indigo, gromwell, fried sanguisorba, giant knotweed, carpet bugle, borneol and phellodendron bark. The traditional Chinese medicine composition provided by the invention is convenient to use and coat on an affected part for skin absorption, is easy to wash off and convenient to change dressing, can keep the surface of a wound wet, can prevent bacterial invasion, is capable of quickly alleviating pain, diminishing inflammation and relieving itching, and can promote the surface of a wound to heal quickly and reduce scar. In addition, the traditional Chinese medicine composition has short period of treatment, an obvious curative effect and no obvious toxic or side effect, has obvious efficacies of antibiosis, alleviating pain, subduing swelling, diminishing inflammation, adsorbing, converging, removing necrosis and promoting granulation, and is used through oral administration and external application with quite good effect.

A compound preparation consists of ornithine or its salt and asparagic acid or its salt as well as proper amount of supplementary material; and is prepared into oral preparation or injection through mechanical mixing and other process. The said compound preparation is used for treating various acute hepatitis, chronic hepatosis and hepatic encephacopathy and has the obvious effects of protecting liver and strengthening physique. The preparation process is simple, short in production period and low in cost.

A Chinese medicine in the form of particles for treating cervical spondylopathy, especially the nerve root type one, is prepared from 7 Chinese-medicinal materials including notoginseng, Chuan-xiong rhizome, white peony root, clematis root, etc. through pretreating, crushing, solvent extraction, purifying, concentrating, drying and granulating.

The invention provides a cassia obtusifolia tea bag with functions of weight reduction, hypotension and hypoglycemic effect, which is characterized in that the production process comprises the following steps: washing, cleaning and drying the cassia obtusifolia stem, leaf and grain, crushing by a pulverizer to 280 meshes, uniformly stirring, packing, disinfecting to obtain the cassia obtusifolia tea bag with functions of lipid lowering, hypotension and hypoglycemic effect. The optimal composition and the weight part ratio of the tea bag are: 40-60 parts of dried cassia obtusifolia stem, leaf and grain, 10 parts of dried lotus leaf, 5 parts of haw, 5 parts of dried balsam pear, 5 parts of Chinese wolfberry, 10 parts of Pu'er tea, 10 parts of cassia seed, 5 parts of mulberry leaf, 5 parts of folium apocyni veneti, 5 parts of Chinese yam as medicine, 3 parts of rhubarb, 2 parts of chrysanthemum, 2 parts of honeysuckle flower, 1 part of boat-fruited sterculia, 5 parts of cassia seed, 5 parts of kudzu root and 10 parts of additive. The additive is composed of fatty acid sucrose ester, xylitol, mannitol crystal, natural menthol, citric acid, trisodium phosphate, sodium saccharin and steviosid; the above components are carried out the processes of crushing, mixing, uniformly stirring, packing and disinfecting to obtain the tea bag.

The invention is an intelligent wean amblyopia and askant diagnosis and therapeutic apparatus made up of computer, monitor, keyboard, program sensor mouse, blue and red glasses and printer. The computer stores embedded vision function diagnosing software which can complete diagnosis of amblyopia and askant and therapy function. According to modern vision theory, it integrates several kinds of traditional therapeutic apparatus function with computer multi-media technology, realizes the integration of diagnosis, therapy and case recording. It applies to diagnosis of vision function of eyes such as eyesight, and contrast susceptibility. The product can diagnose and cure according to children in different age, the intelligent degree is high; it can upgrade the eyesight of children, improves the functions of eyes; it can carries on double-eye single-vision train before or after operation, solidifies the operation effect.

The invention discloses a medicament for treating dyspepsia, which is prepared by the following raw materials by weight: 12-30 parts of medicated leaven, 10-30 parts of jujube, 10-30 parts of radish seeds, 8-25 parts of rhizoma atractylodis macrocephalae, 8-25 parts of poria cocos, 5-20 parts of licorice, 8-25 parts of chicken gizzard membrane, 8-20 parts of forsythia suspense, 8-20 parts of citrus aurantium, 5-15 parts of tangerine peel, 5-15 parts of hawthorn, 5-15 parts of perillaseeds, 8-20 parts of cardamom, 10-30 parts of mangnolia officinalis, 8-20 parts of rhizoma cyperi, 3-8 parts of amomum tsao-ko, 10-20 parts of fructus amomi, 12-25 parts of rhizoma atractylodis, 8-18 parts of pericarpium citri reticulatae viride, 5-15 parts of radix auckladiae, 3-8 parts of hyacinth bean. The medicament for treating dyspepsia of the invention has good effect of strengthening stomach and promoting digestion, invigorating spleen and tonifying qi, regulating qi and relieving pain, assisting digestion, and can treat symptoms such as abdominal discomfort or pain, distension, heartburn (acid regurgitation), eructation, anorexia or less intake, difficult sleeping and eating caused by dyspepsia.

An exterior-applied Chinese medicine for treating multiple skin diseases including itching, inflammatory and viral dermatopathies is prepared from chloromycetin, fossyol, and 13-15 Chinese-medicinal materials including rhubarb, phellodendron bark, dittany bark, flavescent sophora root, etc.

The invention relates to a traditional Chinese medicine for treating cardiac, cerebral and vascular diseases; the drug is composed of forty kinds of crude drugs by weight parts: milk veteh, salvia miltiorrhiza, root of common peony, ligusticum wallichii, lumbricus, sanguisuga, rhizoma acori graminei, polygala root, red ocher, oyster, angelica, the root of kudzu vine, arisaema cum bile and the like; the preparation method is that: (1) the crude drugs are prepared into water extract liquid; (2) the water extract liquid is prepared into oral liquid; (3)the water extract liquid obtained by the step (1) is dried, crushed, sieved, undersize material is extracted powder; (4) the extracted powder prepared by the step (3) is prepared into various dosage forms. The preparation method of crude powder is that: lime earth of the crude drugs is sieved, and then the crude drugs are crushed and sieved, the undersize material is taken out and is sterilized to be crude powder, and the crude powder is prepared into various dosage forms. The traditional Chinese medicine has the major functions of treating miocardial infarction and angina caused by coronary heart disease, high blood pressure and cerebral thrombosis, hemiplegia, cerebral infarction, cerebrovascular accident, sequel of apoplexy and other symptoms, and the medicine has obvious effect on headache, dizziness and heart cerebrovascular diseases caused by high blood pressure and cerebral circulation insufficiency.