528 results about "Diabetic foot" patented technology

The invention discloses a diabetic foot risk assessment method and system based on big data, and relates to the technical field of intelligent medicines.The method comprises the steps that multi-dimensional physiological data is collected in real time, and the multi-dimensional physiological data collected in real time is preprocessed; extracting physiological features based on the preprocessed multi-dimensional physiological data, and fusing the physiological features into a multi-dimensional feature vector; constructing a personalized health baseline model, inputting the multi-dimensional feature vector into the personalized health baseline model, and predicting a personalized safety baseline; comparing the physiological features with the personalized safety baseline, formulating a nonlinear penalty function P based on the deviation between each physiological feature and the corresponding personalized safety baseline, predicting the influence degree of the deviation of each physiological feature on the overall health state of the patient, and evaluating the current diabetic foot risk of the patient. Through personalized health baseline prediction, the accuracy and reliability of risk assessment are improved, and the method has significant advantages especially in early warning and personalized health management of diabetic feet.

The invention discloses a diabetic foot assessment method based on wound image recognition. The method comprises the following steps: processing a foot infrared thermal imaging image to generate a temperature anomaly graph; fusing the foot wound image and the temperature anomaly graph to generate a fused image; constructing a foot blood flow analysis model, extracting a blood flow influence factor, and correcting the fused image through the blood flow influence factor; and constructing a joint assessment model, taking the corrected fusion image and historical data of the diabetic foot patient as input of the joint assessment model, predicting a risk assessment level of the diabetic foot, and outputting a disease assessment result of the diabetic foot patient according to the risk assessment level. According to the method, multi-modal medical image fusion analysis is realized, the accuracy of wound area positioning and pathological state expression is improved, the accuracy of lesion area recognition is improved, the illness worsening risk can be predicted in advance, clinical decision can be assisted, the risk of serious complications such as amputation of a patient is reduced, and the prognosis and life quality of the patient are improved.

The invention relates to the field of diabetic feet, and discloses a diabetic foot risk assessment method and system based on a knowledge graph, and the method comprises the steps: collecting patient data of diabetic feet, recognizing patient group features, risk factors and risk features of the diabetic feet, constructing a risk prediction model of the diabetic feet, extracting keywords from risk prediction data of the risk prediction model so as to query domain knowledge of the diabetic foot, constructing a diabetic foot ontology structure, identifying an entity object of the ontology structure, performing disambiguation processing, extracting entity data of the entity object from the domain knowledge, and obtaining a disambiguation result of the entity object according to the disambiguation result and the entity data. The storage knowledge of the diabetic foot is fused, the reasoning conclusion of the diabetic foot is obtained by combining the reasoning rule and the reasoning type, the risk factor and the risk level of the patient data are recognized, and a risk assessment report of the diabetic foot is generated. The accuracy of diabetic foot risk assessment can be improved.

The invention relates to the technical field of image processing, and provides a CT angiography clear imaging method and system for a diabetic foot patient, and the method comprises the steps: collecting a CT angiography image, converting the CT angiography image into a CT angiography gray image, and dividing a suspected blood vessel edge; marking a target suspected blood vessel edge, and obtaining a gray level similar weight of the target suspected blood vessel edge; extension feature similarity is obtained, interference object confidence coefficients of two different suspected blood vessel edges are obtained, and all blood vessel pixel points are screened; and according to the position distribution of all blood vessel pixel points in the CT angiography grayscale image and the pixel values of the pixel points of all image columns in the CT angiography grayscale image, performing interpolation processing on the CT angiography grayscale image to obtain a CT angiography clear imaging result of the diabetic foot patient. The problem that interferents such as bones are mixed with blood vessels, and the image enhancement efficiency of CT angiography images is reduced is solved.

The invention relates to the technical field of medical education, in particular to a virtual patient skin care teaching system with enhanced pathological features and a method thereof, the system comprises pathological feature generation, parameter control, physical modeling, intelligent evaluation and a multi-mode feedback module, and can edit and simulate various skin pathological features in real time, such as pressure sores and diabetic feet, so that the system can be applied to the field of medical education. The visual display of the lesion degree is realized through a five-segment color mapping system, the system also simulates percolate reflection and cuticle spalling, the sense of reality is enhanced, the intelligent assessment module provides risk assessment and healing prediction according to physiological and morphological parameters, the multi-modal feedback module integrates visual sense, tactile sense and user behavior feedback, the interactive experience is improved, and the system is suitable for popularization and application. And the adaptive optimization module dynamically adjusts system parameters according to user feedback and learning effects, and provides personalized teaching. Compared with a traditional method, the method is higher in parameter control precision, supports personalized teaching, and is of great significance to medical education.

The present invention provides a dressing capable of promoting healing of a chronic wound. Specifically, provided is a multifunctional wound dressing, comprising: first active components: β-nicotinamide mononucleotide (NMN), nicotinamide adenine dinucleotide (NAD+), or a combination thereof; and a dressing matrix. Experiments of the present invention prove that the multifunctional wound dressing of the present invention has an excellent effect of promoting healing of chronic refractory wounds such as diabetic feet.

The invention discloses a diabetic foot early-stage detection method combining infrared and visible light imaging, and relates to the technical field of diabetic foot medical imaging diagnos.The diabetic foot early-stage detection method comprises the steps that multi-mode image collection and standardization processing are conducted, infrared images and visible light images are synchronously collected, and standardization processing such as size normalization is conducted; image registration and space alignment are carried out, marking points are set based on foot anatomical features, and feature extraction, mismatching point elimination and transformation matrix calculation are carried out; extracting and screening multi-dimensional features, extracting temperature and structural features, and screening by using a Relief-F algorithm; feature lesion recognition and classification are fused, and lesion probability is output through a double-branch convolutional neural network; carrying out detection result verification and feedback optimization, and comparing a clinical diagnosis optimization model; and generating a detection report and storing data, and generating a report containing the fused image. The early lesion detection precision is improved through multi-modal fusion, individual and environment differences are adjusted and adapted in a personalized mode, and reliable technical support is provided for clinic.

The invention relates to an intelligent pressure adjusting insole suitable for a diabetic foot patient, which comprises an intelligent insole structure, a pressure monitoring and gait analysis module, an intelligent fluid control module, a wireless data transmission module, an energy management and power supply system and a user interface and data management module, a pressure monitoring and gait analysis module, an intelligent fluid control module, a wireless data transmission module and an energy management and power supply system are integrated in the intelligent insole structure, and an insole of the intelligent insole structure is of a three-layer structure comprising an upper layer, a middle layer and a lower layer. The intelligent pressure adjusting insole suitable for the diabetic foot patient integrates the functions of high-precision pressure monitoring, gait analysis, intelligent fluid pressure adjustment and wireless data transmission, and aims at effectively preventing and relieving foot complications through intelligent means and improving the comfort and health management level of the patient.

The invention relates to the technical field of biomedical dressings, in particular to a dressing for a diabetic foot wound surface and a preparation method of the dressing. 0.2 to 0.8 part of reduced graphene oxide; 2 to 5 parts of beta-1, 3-glucan modified by chondroitin sulfate; 0.08 to 0.3 part of silver nitrate; 3 to 7 parts of N-isopropyl acrylamide-co-acrylic acid; 0.15 to 0.4 part of N, N '-methylene bisacrylamide; 2 to 5 parts of sulfhydrylated hyaluronic acid; 0.3 to 0.8 part of D-alpha-vitamin E polyethylene glycol succinate; 2 to 5 parts of amino-functionalized mesoporous silica; 1 to 3 parts of L-arginine-L-glutamate; 0.1 to 0.4 part of genipin; the super-strong mechanical property and the super-strong flexibility are realized, so that the dressing can better adapt to the irregular shape of a wound surface, and continuous protection is provided.

The invention relates to the technical field of medical instruments, in particular to a negative pressure treatment system for diabetic feet, which comprises an intelligent negative pressure control module, a multi-cavity flexible dressing, a multi-parameter sensing unit, a data processing terminal, a percolate collecting unit, a monitoring feedback module and a portable power supply, wherein the intelligent negative pressure control module is used for generating, regulating and controlling negative pressure; the multi-parameter sensing unit is used for collecting wound microenvironment physiological parameters; the data processing terminal analyzes the received physiological parameters and wound image data based on an AI algorithm, and sends an instruction to the intelligent negative pressure control module to dynamically adjust the negative pressure intensity and the work cycle; the percolate collecting unit is used for collecting percolate; and an image acquisition module in the monitoring feedback module acquires a wound image. Therefore, the problems that in the prior art, the negative pressure intensity and the work period cannot be dynamically adjusted, effective collection and analysis means for wound microenvironment physiological parameters and image data are lacked, and percolate collection lacks an intelligent monitoring and early warning mechanism are solved.

The invention discloses a diabetic shoe system for plantar pressure monitoring and pressure reduction of a diabetic patient, relates to the technical field of diabetic foot monitoring and rehabilitation, and provides the following scheme that the diabetic shoe system comprises a monitoring shoe, and a plantar pressure monitoring mechanism is laid on the upper surface of the interior of the monitoring shoe; a plantar pressure distribution and pressure reduction mechanism is arranged on the upper surface of the plantar pressure monitoring mechanism, and a bridle mechanism is arranged above the plantar pressure distribution and pressure reduction mechanism. According to the technical scheme, the sole pressure distribution and pressure reduction mechanism composed of the multiple array type air bags is arranged on the sole, the pressure of the sole is monitored by means of the multiple flexible pressure sensors arranged in an array mode, the sole is controlled to incline forwards or backwards or be horizontal by means of different expansion degrees of the multiple air bag sets while the pressing force of the sole is monitored, and therefore the comfort degree of the sole is improved. In a mode of transferring the gravity center of the sole, the pressure is transferred to the heel when the stress of the sole is large, so that ulcer caused by overlarge stress of the half sole of the diabetic foot is prevented.

The embodiment of the invention provides a diabetic foot image classification system and method based on small sample learning. The diabetic foot image classification system based on small sample learning comprises a data enhancement module which is used for carrying out weighted fusion processing on a training image and a similar image on a diabetic foot image to generate an expanded data set; the feature extraction module is used for performing ResNet-101 backbone network feature extraction processing on the expanded data set generated by the data enhancement module to generate a feature tensor comprising global semantics and local details; the attention enhancement module is used for performing double-pool channel attention and enhancement space attention processing on the feature tensor generated by the feature extraction module to generate an attention enhancement feature map focusing on the lesion area; and the classification module is used for performing dynamic prototype aggregation processing on the attention enhancement feature map generated by the attention enhancement module so as to classify the diabetic foot image.

The invention discloses a local oxygen therapy, flushing and skin stretching device for chronic wound treatment, and relates to the technical field of medical apparatuses and instruments, the local oxygen therapy, flushing and skin stretching device comprises a stretching disc, and a cleaning device is arranged in the middle of the stretching disc; according to the device, breakthrough is achieved through the combination of the circular structure of the stretching disc and the circumferentially-distributed T-shaped sliding racks; the circular geometric structure of the stretching disc has stress symmetry, and stretching force can be evenly dispersed; the position of the T-shaped sliding rack installed in a circumferential sliding mode can be flexibly adjusted in the radial direction of the stretching disc, and six or more stretching points can be set at will according to the boundary of the wound surface in cooperation with the sliding block and the T-shaped hook frame which can slide. For example, for an irregular polygonal wound surface of a diabetic foot, a medical worker can mark six stress balance points on the T-shaped sliding rack and fix the hook, synchronous or independent adjustment of multiple distraction points is achieved through linkage of the rotating gear ring and the multiple sets of gears, and the situation that skin ischemia blister is caused by too large local stress or tissue stretching is affected by insufficient stress is avoided.

The invention relates to injectable temperature-sensitive hydrogel loaded with traditional Chinese medicine active exosomes, and belongs to the technical field of clinical treatment of diabetic foot refractory wounds, and the injectable temperature-sensitive hydrogel is obtained by poloxamer 407 hydrogel and a hyaluronic acid loaded composite carrier; the composite carrier body is formed by coating a traditional Chinese medicine active exosome with a coating solution; the traditional Chinese medicine active exosome is obtained by inducing adipose-derived mesenchymal stem cells with a modified astragalus extract. The injectable temperature-sensitive hydrogel is obtained by loading a composite carrier with poloxamer 407 hydrogel and hyaluronic acid, the poloxamer 407 and the hyaluronic acid quickly form a physical barrier on a wound surface after being injected, a moist healing environment is provided, and continuous and slow release of exosome and active ingredients is realized by means of the temperature-sensitive characteristic and the network structure of the poloxamer 407 and the hyaluronic acid, so that the wound healing effect is improved. And over-high local concentration or premature loss caused by sudden release of the medicine is avoided.

The utility model discloses a diabetic foot dressing change support, and relates to the technical field of medical instruments, the diabetic foot dressing change support comprises a support main body, the support main body comprises an outer frame and rollers arranged in the outer frame along the circumferential direction, the rollers are used for bearing feet, and a gap is formed between two adjacent rollers. The gap is used for allowing liquid to penetrate through, and the roller has the rotational freedom degree in the axial direction so that the side, opposite to the gap, of the roller can be separated from the gap. Compared with liquid leakage through holes in the prior art, through the structure of the rotatable roller operation supporting component, thorough cleaning can be achieved by rotating the roller in the cleaning process, and the later cleaning degree of the equipment is guaranteed; the supporting barrel and the liquid collecting barrel are separated, so that the liquid collecting barrel can be independently taken down, liquid in the liquid collecting barrel can be conveniently cleaned, the flexible bag is arranged, the supporting barrel and the liquid are isolated, the liquid collecting barrel and the liquid are also isolated, and the workload of medical staff is reduced.

The invention belongs to the technical field of diabetic foot detection, and provides a diabetic foot monitoring system. Comprising a multi-sensor collaborative data acquisition module, a data preprocessing and feature extraction module, a data encapsulation and transmission module, a time sequence data modeling module, a time sequence data training module, a model lightweight deployment and real-time prediction module, a multi-stage early warning trigger module, a personalized health suggestion generation module and a real-time monitoring module. A local fault diagnosis and abnormity determination module; and a user side interaction and maintenance execution module. By adopting the sensor array, the foot risk is comprehensively reflected, and the wearing experience of a user is improved; low-delay early warning is realized through a local deployment prediction model; by arranging the personalized health suggestion generation module, the threshold value is dynamically adjusted according to the medical history and living habits of the patient, and the personalization of the system is improved.

The invention discloses a diabetic foot management and control method for a diabetic patient and related equipment. The method comprises the following steps: periodically acquiring peripheral neuropathy examination data of a diabetic patient, wherein the period is dynamically determined based on historical diabetes data of the patient; generating a diabetic foot risk assessment problem table based on the peripheral neuropathy examination data and the diabetes historical data; and based on the peripheral neuropathy examination data and feedback data of the patient in response to the risk assessment problem table, predicting the diabetic foot disease risk level of the diabetic patient through a column diagram prediction model. The problem that a simple, feasible and easy-to-popularize diabetic foot prediction method is lacked at present can be solved.

The invention discloses a diabetic foot therapeutic apparatus, which relates to the field of medical instruments, solves the problem of poor therapeutic effect of the diabetic foot therapeutic apparatus, and comprises: a data acquisition module, which is used for respectively acquiring the average number ratio of sample bacteria, the pressure coefficient of an affected area, the oxygen enrichment coefficient of the affected area and the area ratio of a foot affected area to obtain affected foot monitoring data, the data analysis module is used for analyzing the sick foot monitoring data to obtain a first treatment control coefficient, a second treatment control coefficient and a third treatment control coefficient, and sick foot treatment analysis data is obtained; the treatment control module is used for controlling the ultraviolet treatment function, the negative pressure treatment function and the oxygen-enriched treatment function of the diabetic foot treatment instrument according to the diseased foot treatment analysis data, the treatment functions are automatically controlled by obtaining the treatment control coefficient, it is ensured that the treatment process is more accurate, the treatment effect is improved, and wound healing is promoted.

The invention discloses a multi-effect functional exosome aerogel dressing and an application thereof. The aerogel dressing is prepared by taking modified plant cellulose as a matrix, loading a ginseng source exosome, compounding with carboxymethyl chitosan, and carrying out directional freezing and freeze-drying processes. Compared with a traditional dressing, the aerogel material disclosed by the invention has good biocompatibility and a light structure; through reasonable design, triple treatment functions of stopping bleeding, resisting bacteria and promoting wound healing can be achieved at the same time. As a biological material with relatively high transformation potential and application prospect, the aerogel disclosed by the invention can be prepared into medical wound dressings, and is particularly suitable for treatment and management of chronic refractory wounds such as diabetic foot, bedsore, ulcer after burn and the like.

The invention provides a metabolic disease diabetic foot test data early screening method and system. Belongs to the technical field of medical health. The method comprises the following steps: acquiring clinical sample data, transmitting the acquired clinical sample data to a cloud space for preprocessing, performing feature extraction on the preprocessed clinical sample data through a deep learning algorithm, and extracting features related to the metabolic disease diabetic foot; constructing a metabolic disease diabetic foot screening model based on blood routine data through a deep learning algorithm, and combining obtained clinical sample data with historical data to construct a data set; the constructed metabolic disease diabetic foot screening model is evaluated through multiple indexes, and the metabolic disease diabetic foot screening model is optimized based on the evaluation result. Feature extraction is carried out through a deep learning algorithm, complex modes and subtle changes related to the metabolic disease diabetic foot can be recognized, and the screening accuracy is improved.

The present invention relates to an intelligent auxiliary inspection device for diabetic peripheral neuropathy, the inspection device comprising a pressure air pump (1), an infrared distance measuring sensor (2), an intelligent evaluation module (3), a control module (4), an auxiliary handle (5), an indicator light (6), a power supply (7), and a switch (8). Except for the intelligent evaluation module, the various units are combined and wrapped by a shell (9) of a gun-type structure. The air pump is located at the barrel of the gun-type structure. The infrared distance measuring sensor is placed below the air pump and connected to the indicator light. A control module is provided in the gun-type structure for receiving an output signal of the infrared distance measuring sensor and regulating the airflow output of the pressure air pump. The power supply is placed at the magazine of the gun-type structure. The switch is placed at the trigger of the gun-type structure. The advantages of the present invention are that an air pump that generates controllable air pressure is used to replace the traditional 10g nylon monofilament, thereby improving the success rate of pressure sensation detection of diabetic foot peripheral neuropathy, and the invention has a simple structure, can be reused, is easy to operate, and is convenient to use. The intelligent evaluation module is attached to evaluate the degree of peripheral neuropathy of the patient.

The utility model discloses a diabetic foot rehabilitation nursing support which comprises a support body, protective cloth used for bearing and supporting the legs of a diabetic foot patient is arranged on the inner side of the support body, the protective cloth is hung on the support body through hanging structures at the two ends, and the hanging structures adjust the hanging height of the protective cloth by adjusting the folding amount. Bottom wheels are arranged at the four corners of the bottom of the support in a sleeving mode, and the support can directly land on the ground or land on the ground through the bottom wheels by moving the bottom wheels. The utility model relates to the technical field of leg nursing supports. According to the diabetic foot rehabilitation nursing support, an affected limb is lifted through the lifted protective cloth, medical dressings can be placed, tissue and skin can be effectively protected, the lifting face is large, the affected limb tissue is protected, diabetic foot rehabilitation is facilitated, the size is moderate, quilt covering is allowed, the protective cloth can be adjusted to different heights by adjusting the folding degree of the hanging structure, a patient feels more comfortable, and the patient can feel more comfortable. And the protective cloth can be adjusted to form a certain angle, so that blood flows back.

The invention discloses a preparation method of antisense nucleic acid antibacterial hydrogel for diabetic foot wound healing, and belongs to the technical field of biological materials.The preparation method comprises the steps that 12 nt antisense nucleic acid is designed according to a yycF promoter-10 region sequence, and a 24 nt double-chain nucleic acid structure is formed through base complementation of a 5'end sequence and a 3 'end sequence; loading a 24nt double-chain nucleic acid structure onto the graphene oxide to form a stable long-chain structure; the obtained stable long-chain structure is combined with SIS biological hydrogel, and functional gel with antibacterial antisense nucleic acid is prepared; basic fibroblast growth factors are added into the functional gel, and the antisense nucleic acid antibacterial hydrogel for diabetic foot wound healing is prepared. The problem of difficult wound healing of the diabetic foot is solved from the microscopic perspective by designing antisense nucleic acid.

The invention relates to the technical field of non-invasive monitoring, in particular to a diabetes blood glucose fluctuation trend prediction method based on foot temperature and humidity change, which comprises the following steps: continuously collecting temperature, humidity and motion data of multiple areas of a foot through a foot wearable device, extracting a feature set related to blood glucose fluctuation from the preprocessed data, and calculating the blood glucose fluctuation trend according to the feature set; and fusing the feature set and context event information, inputting the fused feature set and context event information into a multi-task deep learning prediction model, visually displaying a prediction result in the forms of a trend arrow, a probability interval and a risk level, and triggering early warning in advance when a hyperglycemia or hypoglycemia event is predicted to be about to occur. The method is completely noninvasive and high in compliance, prospective trend prediction can be carried out based on existing diabetic foot monitoring wearable equipment, individual physiological characteristics of a user can be continuously learned through a built-in personalized self-adaptive mechanism, dynamic calibration is carried out on the model through incremental learning, and the prediction accuracy is improved. And the prediction precision is continuously improved along with the use time.

The invention relates to the technical field of big data processing, in particular to a temperature and humidity data dynamic calibration and compensation method for wearable medical equipment, and the method comprises the following steps: multi-parameter data synchronous acquisition, sweat evaporation cooling effect compensation, pressure-temperature sensitivity compensation, and dynamic baseline drift correction. The method further comprises abnormal value filtering based on physiological laws and cloud collaborative calibration. According to the method, high-precision dynamic compensation and calibration of temperature and humidity data are realized in a mode of combining multi-sensor cooperative sensing, physical mechanism modeling and dynamic baseline correction, so that the problem of data misalignment of wearable medical equipment in a complex use environment is solved; and a reliable technical support is provided for accurate monitoring and early intervention of diseases such as diabetic foot and the like.

The invention relates to the technical field of big data processing, in particular to a multi-source data fusion generation method for a diabetic foot health status assessment report, which comprises the following steps of: firstly, converging and preprocessing multi-modal heterogeneous data from wearable equipment, clinical input and historical records; the method comprises the following steps of: firstly, extracting data by using an attention mechanism-based deep learning network, then extracting deep correlation features among the data by using an attention mechanism-based deep learning network, then analyzing fusion features through a mixed decision engine combining rule reasoning and a machine learning model, generating structured risk assessment tags, and finally, dynamically calling parameterized templates by a system according to the tags, thereby realizing risk assessment. And a natural language generation technology is utilized to output an interactive visual evaluation report capable of performing personalized rendering according to a user role. According to the method, multi-source data can be automatically fused, deep analysis is carried out, a personalized, dynamic and interactive report is generated, and original and isolated monitoring data is converted into intelligent insight capable of guiding clinical actions.

The invention relates to the technical field of medicine, in particular to a diabetic foot debridement device which comprises a base and a plurality of universal wheels. The device further comprises a supporting assembly. The supporting assembly comprises two lifting mechanisms, a supporting plate and a leg fixing mechanism. The two lifting mechanisms are used for driving the supporting plate to ascend and descend, the leg fixing mechanism is installed on the supporting plate, in the specific using process, the two lifting mechanisms are utilized for adjusting the leg fixing mechanism to the proper height position according to the position of a diabetic, then the ankle of the diabetic is fixed to the leg fixing mechanism, and then the ankle of the diabetic is fixed to the leg fixing mechanism. The leg fixing mechanism is used for supporting the ankles of the diabetic patient, so that the sick feet of the diabetic patient are suspended from one side, and then medical staff can debridement the sick feet; whether a diabetic sits on a chair or lies on a bed, the device can be used in a matched mode, and adaptive adjustment can be conducted according to the height of the legs of the patient.

The invention belongs to the field of medicine, and provides cream for treating pressure sores and diabetic feet and a preparation method thereof.The cream is prepared from a component A, a component B, a component C and a component D. The component A is prepared from, by mass, 10-40 parts of ligustrum sinense leaves, 10-40 parts of angelica sinensis, 10-40 parts of sanguisorba officinalis, 10-40 parts of golden cypress, 10-40 parts of liquorice, 10-40 parts of radix angelicae, 10-40 parts of polygonum cuspidatum and 10-40 parts of dried rehmannia glutinosa; the component B is prepared from the following components in parts by mass: 10 to 30 parts of rhizoma coptidis, 10 to 30 parts of radix et rhizoma rhei, 10 to 30 parts of radix paeoniae rubra, 10 to 30 parts of radix scrophulariae, 10 to 30 parts of cortex moutan, 10 to 30 parts of radix astragali seu hedysari and 10 to 30 parts of rhizoma chuanxiong; the component C is prepared from the following components in parts by weight: 10 to 15g of radix lithospermi, 3 to 10g of borneol and 5 to 10g of beewax; the component D is 500g of medical vaseline; through a specific traditional Chinese medicine composition, pressure sores and diabetic feet can be effectively treated, related symptoms can be remarkably relieved, and meanwhile animal experiments show that the traditional Chinese medicine cream is free of toxic and side effects.

This invention belongs to the field of medical device technology and discloses a foot pressure relief device for diabetic foot. It includes a base, a pressure relief plate and a motor connected to the base, and a foot pedal and a transmission assembly connected to the pressure relief plate. The transmission assembly includes a crank, a first connecting rod, and a sliding seat. The crank is fixedly connected to the output shaft of the motor, and the sliding seat is connected to the pressure relief plate. The two ends of the first connecting rod are respectively connected to the crank and the sliding seat. The sliding seat is connected to a foot rolling shaft and a second connecting rod, and the second connecting rod is connected to a foot massage roller. A buffer spring is provided between the pressure relief plate and the base. The foot pedal has a through groove, and the foot rolling shaft is connected to a foot massage roller. This invention utilizes the foot rolling shaft / foot massage roller and the foot massage roller to simultaneously perform rolling massage on the sole and instep of the foot. The periodic oscillation of the pressure relief plate causes the heel and toes to alternately rise, resulting in good pressure relief for the foot.

According to the application of the dipsacus asper saponin VI in regulating and controlling the differentiation of the surface stem cells, the brand new pharmacological action of the dipsacus asper saponin VI in targeted promotion of the differentiation of the epidermal stem cells is found for the first time, the cognitive limitation of the prior art is broken through, a brand new target spot and direction are provided for research and development of innovative drugs for wound repair, and the application of the dipsacus asper saponin VI in regulating and controlling the differentiation of the epidermal stem cells is realized. A medicine containing teasel saponin VI is adopted, epidermal stem cells are taken as a core target, wound reepithelialization is accelerated by promoting directional differentiation of the epidermal stem cells, the mechanism is clear, the targeting property is high, a core link capable of directly hitting wound healing is adopted, epidermal stem cell differentiation is regulated in a targeted manner, and meanwhile, the medicine has the synergistic effects of resisting inflammation and promoting angiogenesis; the obvious application potential is realized on refractory wounds such as diabetic feet and pressure sores.