An enclosure for tablet devices with features to provide secure mounting options is described. In accordance with at least one embodiment, the enclosure provides options to mount a tablet device in either a desktop stand or onto a variety of other supports, including VESA compliant mounts and electrical junction boxes. Security options include the ability to secure the tablet device inside the enclosure to provide a deterrent to theft or vandalism. Additional levels of security may be provided that limit access to the tablet device's control features (i.e., control buttons, cameras, sensors). In accordance with at least one embodiment, access to the tablet device's display, button(s), camera(s), microphone(s), speaker(s), connector(s), and/or tactile feedback of button(s) or other devices can be selectively maintained or prevented while the tablet device is enclosed in the tablet enclosure.