19299results about How to "Improve effectiveness" patented technology

A method and apparatus for allowing the user of an electronic device to enhance privacy over a display with the use of software, are disclosed. A security window including a translucent graphical effects region may be displayed on the electronic device such that it overlays content the user may choose to protect. The security window allows the protected content to remain discernable for the user of the device yet substantially indiscernible to a person at a further distance and / or greater viewing angle from the screen of the device. One or more security windows, each of which may be of any size, shape, texture, translucency level and any other graphical or behavioral properties may be displayed on the display associated with the electronic device. The user may control the size, shape, texture, translucency level and any other graphical or behavioral properties of the security window and graphical effects region. The user may invoke or terminate a security window with the single click of a button. Security windows may automatically attach to applications in focus, or be attached in response to a user command, and allow uninterrupted usability of those applications.

The invention is based, at least in part, on the development of stabilized binding molecules that consist of or comprise a stabilized scFv and methods for making such stabilized molecules.

A wafer carrier is provided. The wafer carrier includes a storage holding member for storing a plurality of wafers and includes a plurality of open portions. The wafer carrier further includes a front fixing plate and a rear fixing plate disposed at a front and a rear end of the storage holding member, respectively. The front and rear fixing plates each face a side of at least one of the plurality of wafers. Moreover, left and right edges of the plurality of wafers stored in the storage holding member are exposed by the plurality of open portions.

The present invention provides novel, serum-stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and / or administering the lipid particles. More particularly, the present invention provides serum-stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (e.g., one or more interfering RNA molecules), methods of making the SNALP, and methods of delivering and / or administering the SNALP (e.g., for the treatment of cancer). In particular embodiments, the present invention provides tumor-directed lipid particles that preferentially target solid tumors. The tumor-directed formulations of the present invention are capable of preferentially delivering a payload such as a nucleic acid to cells of solid tumors compared to non-cancerous cells.

A surgical fastener apparatus includes a handle, a flexible elongate segment and an end effector having a fastener cartridge with a plurality of fasteners and an anvil, an approximator member movable relative to the longitudinal axis to cause relative movement of the fastener cartridge and the anvil between an open condition and an approximated condition, a fastener drive to deploy the fasteners from the fastener cartridge for crimping by the anvil, at least one tissue grasper at least partially extending along the end effector and movable to engage tissue and draw the tissue between the fastener cartridge and the anvil when in the open condition, and at least one manual actuator to actuate at least one of the approximator member, the fastener drive or the at least one tissue grasper.

The present invention provides compositions and methods for the delivery of interfering RNAs that silence APOB expression to liver cells. In particular, the nucleic acid-lipid particles provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of APOB at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

Bi-directional and multi-axial fabrics, fabric composites, ballistically resistant assemblies thereof, and the methods by which they are made. The fabrics are comprised of sets of strong, substantially parallel, unidirectional yarns lying in parallel planes, one above the other, with the direction of the yarns in a given plane rotated at an angle to the direction of the yarns in adjacent planes; and one or more sets of yarns having lower strength and higher elongation interleaved with the strong yarns. The fabrics of the invention provide superior ballistic effectiveness compared to ordinary woven and knitted fabrics but retain the ease of manufacture on conventional looms and knitting machines.

The present inventions provide an integrated, modular array of administrative and support services for electronic commerce and electronic rights and transaction management. These administrative and support services supply a secure foundation for conducting financial management, rights management, certificate authority, rules clearing, usage clearing, secure directory services, and other transaction related capabilities functioning over a vast electronic network such as the Internet and / or over organization internal Intranets.These administrative and support services can be adapted to the specific needs of electronic commerce value chains. Electronic commerce participants can use these administrative and support services to support their interests, and can shape and reuse these services in response to competitive business realities.A Distributed Commerce Utility having a secure, programmable, distributed architecture provides administrative and support services. The Distributed Commerce Utility makes optimally efficient use of commerce administration resources, and can scale in a practical fashion to accommodate the demands of electronic commerce growth.The Distributed Commerce Utility may comprise a number of Commerce Utility Systems. These Commerce Utility Systems provide a web of infrastructure support available to, and reusable by, the entire electronic community and / or many or all of its participants.Different support functions can be collected together in hierarchical and / or in networked relationships to suit various business models and / or other objectives. Modular support functions can combined in different arrays to form different Commerce Utility Systems for different design implementations and purposes. These Commerce Utility Systems can be distributed across a large number of electronic appliances with varying degrees of distribution.

The present invention is directed to techniques for providing retail customers a seamless, individualized discovery and shopping experience. With an improved shopper / customer accounting system, along with other technologies such as intelligent fixtures, mobile devices, and product simulations, a shopper's product discovery, purchase, and post-sale experience can be highly integrated and personalized. For example, the shopper's out-of-store (online) and in-store product discovery sessions may be seamlessly linked and analyzed to provide the shopper with customized recommendations and assistance. Other variations and enhancements are disclosed.