A nutraceutical composition and method of use thereof includes core ingredients, huperzine A, dimethylaminoethanol (DMAE), thiamin, niacin, and pantothenic acid. The core ingredients provide a synergistic effect to improve and support cognitive function, such as learning, thinking, and judging and to promote alertness, awareness, attention and mental clarity. Combinations of additional ingredients, such as vinpocetine, acetyl-L-carnitine, L-pyroglutamic acid, pyridoxine, folic acid, vitamin B12, phosphatidylserine, L-theanine, and rhodiola rosea can be added to the core ingredients to enhance the beneficial and synergistic effects of the composition.