19329results about How to "Improve effectiveness" patented technology

A method and apparatus for allowing the user of an electronic device to enhance privacy over a display with the use of software, are disclosed. A security window including a translucent graphical effects region may be displayed on the electronic device such that it overlays content the user may choose to protect. The security window allows the protected content to remain discernable for the user of the device yet substantially indiscernible to a person at a further distance and / or greater viewing angle from the screen of the device. One or more security windows, each of which may be of any size, shape, texture, translucency level and any other graphical or behavioral properties may be displayed on the display associated with the electronic device. The user may control the size, shape, texture, translucency level and any other graphical or behavioral properties of the security window and graphical effects region. The user may invoke or terminate a security window with the single click of a button. Security windows may automatically attach to applications in focus, or be attached in response to a user command, and allow uninterrupted usability of those applications.

Systems and methods are provided for performing a search based on a snapshot image captured from media content presented to a user. The snapshot image contains features of the media content that the user wishes to target for the search. A search system recognizes features of the snapshot image and creates a search query based on the snapshot image. The search query is used to identify features of the snapshot image, and search results related to the identified features are presented to the user. Supplemental data or user input received with the snapshot image may be used in analyzing and identifying features of the snapshot image.

Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.

The instant invention describes methods of separating or preferentially synthesizing dimers which are linked via at least one interchain disulfide linkage from dimers which are not linked via at least one interchain disulfide linkage from a mixture comprising the two types of polypeptide dimers. These forms can be separated from each other using hydrophobic interaction chromatography. In addition, the invention pertains to connecting peptides that result in the preferential biosynthesis of dimers that are linked via at least one interchain disulfide linkage or that are not linked via at least one interchain disulfide linkage. The invention also pertains to compositions in which a majority of the dimers are linked via at least one interchain disulfide linkage or are not linked via at least one interchain disulfide linkage. The invention still further pertains to novel binding molecules, e.g., comprising connecting peptides of the invention.

A wafer carrier is provided. The wafer carrier includes a storage holding member for storing a plurality of wafers and includes a plurality of open portions. The wafer carrier further includes a front fixing plate and a rear fixing plate disposed at a front and a rear end of the storage holding member, respectively. The front and rear fixing plates each face a side of at least one of the plurality of wafers. Moreover, left and right edges of the plurality of wafers stored in the storage holding member are exposed by the plurality of open portions.

An electronic device, with a touch-sensitive surface and a display, includes one or more sensors to detect intensity of contacts with the touch-sensitive surface. The device displays, on the display, a first control for controlling a first operation. The device detects, on the touch-sensitive surface, a first input that corresponds to the first control; and in response to detecting the first input: in accordance with a determination that the first input meets first control-activation criteria but does not include a contact with a maximum intensity above a respective intensity threshold, the device performs the first operation; and in accordance with a determination that the first input includes a contact with an intensity above the respective intensity threshold, the device displays a second control for performing a second operation associated with the first operation.

The present invention provides novel, serum-stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and / or administering the lipid particles. More particularly, the present invention provides serum-stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (e.g., one or more interfering RNA molecules), methods of making the SNALP, and methods of delivering and / or administering the SNALP (e.g., for the treatment of cancer). In particular embodiments, the present invention provides tumor-directed lipid particles that preferentially target solid tumors. The tumor-directed formulations of the present invention are capable of preferentially delivering a payload such as a nucleic acid to cells of solid tumors compared to non-cancerous cells.

A skin or body treatment device includes one or more removable and replaceable modules. Each module is configured to provide a skin or body treatment, underlying tissue treatment, or both. One or more applicators are coupled with the skin or body treatment device. Each applicator enables the use of the one or more removable modules to effect the skin or body or underlying tissue treatment. A selected skin or body treatment, underlying tissue treatment, or both can be implemented and performed upon selection and configuration of the one or more removable and replaceable modules and the one or more applicators required for the selected treatment.

This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device when used in tortuous anatomy.

The invention relates to a method for managing file folder and related equipment. A multifunctional equipment displays a plurality of selective user interface objects on a display device; for responding to the detected first input, the equipment moves the first of the plurality of selective user interface objects on the display device to a position adjacent to the second of the plurality of selective user interface objects on the display device; and for responding to satisfying the predetermined file folder creation criterion, the equipment creates a file folder containing the first and the second object, wherein the file folder creation criterion is that: the first object is adjacent to the second object, while a first input is detected.

An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

The invention provides a nail barn of a linear type cutting closer, comprising a body extending along the longitudinal direction. The body comprises a top face and side faces, wherein the top face is provided with nail holes and cutting grooves; the nail holes are provided with suturing nails; and the distance from the central line of the cutting grooves to the central line of the adjacent nail holes is 1.85 mm to 1.95 mm. In the invention, a stitched tissue is not easy to remove from the nail, and a knife can well complete cutting of the tissue, thereby enhancing the safety of appliances.

A surgical fastener apparatus includes a handle, a flexible elongate segment and an end effector having a fastener cartridge with a plurality of fasteners and an anvil, an approximator member movable relative to the longitudinal axis to cause relative movement of the fastener cartridge and the anvil between an open condition and an approximated condition, a fastener drive to deploy the fasteners from the fastener cartridge for crimping by the anvil, at least one tissue grasper at least partially extending along the end effector and movable to engage tissue and draw the tissue between the fastener cartridge and the anvil when in the open condition, and at least one manual actuator to actuate at least one of the approximator member, the fastener drive or the at least one tissue grasper.

A method of supporting mass human-interaction events, including: providing a mass interaction event by a computer network (100) in which a plurality of participants (102) interact with each other by generating information comprising of questions, responses to questions and fact information for presentation to other participants and assimilating information: and controlling, automatically by a computer (104) the rate of information presentation to each participant, to be below a maximum information assimilation rate of each participant.

The present disclosure generally relates to context-based endpoint detection in user speech input. A method for identifying an endpoint of a spoken request by a user may include receiving user input of natural language speech including one or more words; identifying at least one context associated with the user input; generating a probability, based on the at least one context associated with the user input, that a location in the user input is an endpoint; determining whether the probability is greater than a threshold; and in accordance with a determination that the probability is greater than the threshold, identifying the location in the user input as the endpoint.

A rotary microactuator-based head-gimbal assembly design controls the unwanted deflection of a flexure in a data storage device and eliminates hinge deformation. The head-gimbal assembly maintains the co-planarity of the hinged islands in the microactuator under the applied load acting on the flexure and two associated hinged islands. The dimple post is placed at the dimple loading region of the flexure tongue and has the same height as adhesive dams on paddles secured to the hinged islands. The dimple post is formed by branching one of the existing conductive traces covered by a photoresist layer to the dimple loading region on flexure tongue. In an alternative embodiment, the dimple post is secured to the dimple loading region of the flexure tongue by means of adhesives with a variety of viscosity and elastic moduli.

The present invention provides compositions and methods for the delivery of interfering RNAs that silence APOB expression to liver cells. In particular, the nucleic acid-lipid particles provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of APOB at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

Bi-directional and multi-axial fabrics, fabric composites, ballistically resistant assemblies thereof, and the methods by which they are made. The fabrics are comprised of sets of strong, substantially parallel, unidirectional yarns lying in parallel planes, one above the other, with the direction of the yarns in a given plane rotated at an angle to the direction of the yarns in adjacent planes; and one or more sets of yarns having lower strength and higher elongation interleaved with the strong yarns. The fabrics of the invention provide superior ballistic effectiveness compared to ordinary woven and knitted fabrics but retain the ease of manufacture on conventional looms and knitting machines.

A method and apparatus for reducing the workload of titrating drug to effect while leaving clinician users in control of a related procedure is described. A drug delivery device is controlled to achieve a target drug concentration at a selected site in the patient or a predetermined infusion rate waveform. The time profile of the target drug concentration or a predetermined infusion rate waveform is controlled by a drug state model that uses clinical heuristics to implement safe, pre-defined changes in the target drug concentration or infusion rate and user-commanded changes in target drug concentration or infusion rate. The invention allows time to assess the response of the patient to changes in drug level by making small incremental and conservative changes in drug level over time.

An electronic device implements dictation-based editing of textual data. The device receives a natural-language user input and determines whether the natural-language user input includes a predefined editing command. If the natural-language user input includes the predefined editing command, the device modifies the textual data in accordance with the predefined editing command. If the natural-language user input does not include the predefined editing command, the device transcribes the natural-language user input and adds the transcribed text to the textual data.

The present inventions provide an integrated, modular array of administrative and support services for electronic commerce and electronic rights and transaction management. These administrative and support services supply a secure foundation for conducting financial management, rights management, certificate authority, rules clearing, usage clearing, secure directory services, and other transaction related capabilities functioning over a vast electronic network such as the Internet and / or over organization internal Intranets.These administrative and support services can be adapted to the specific needs of electronic commerce value chains. Electronic commerce participants can use these administrative and support services to support their interests, and can shape and reuse these services in response to competitive business realities.A Distributed Commerce Utility having a secure, programmable, distributed architecture provides administrative and support services. The Distributed Commerce Utility makes optimally efficient use of commerce administration resources, and can scale in a practical fashion to accommodate the demands of electronic commerce growth.The Distributed Commerce Utility may comprise a number of Commerce Utility Systems. These Commerce Utility Systems provide a web of infrastructure support available to, and reusable by, the entire electronic community and / or many or all of its participants.Different support functions can be collected together in hierarchical and / or in networked relationships to suit various business models and / or other objectives. Modular support functions can combined in different arrays to form different Commerce Utility Systems for different design implementations and purposes. These Commerce Utility Systems can be distributed across a large number of electronic appliances with varying degrees of distribution.

The present invention is directed to techniques for providing retail customers a seamless, individualized discovery and shopping experience. With an improved shopper / customer accounting system, along with other technologies such as intelligent fixtures, mobile devices, and product simulations, a shopper's product discovery, purchase, and post-sale experience can be highly integrated and personalized. For example, the shopper's out-of-store (online) and in-store product discovery sessions may be seamlessly linked and analyzed to provide the shopper with customized recommendations and assistance. Other variations and enhancements are disclosed.

A communication system architecture (SA) for a vehicle which may be integrated into the vehicle's multiplexed electronic component communication system, and a process for communicating with the vehicle to provide information for and about the vehicle's operational status and coordinating the vehicle's activities. The communication system will include a multi-functional antenna system for the vehicle that will have the capability to receive AM / FM radio and television signals, and transmit and receive citizens band (CB) radio signals, satellite and microwave and cellular phone communications. The antenna may be installed as original equipment or as a back-fit part in the after-market. In either case the multi-functional antenna will be integrated with the vehicle's multiplexed electronic component communication system. The process for communicating with the vehicle will involve a communication service for which the vehicle's driver will enroll for and service will continue so long as maintenance fees are paid. The service will be capable of providing various levels of information transfer and coordination. The levels may include vehicle information such as (1) the need for servicing and location of the nearest service center with the necessary parts in stock, (2) routing, and (3) load brokering and coordination. The modular design of the system architecture (SA) will allow it to be employed with the vehicle platform that does not possess a full multiplexed electronic component communications system. The resulting vehicle, using an after-market application package, will be able to participate in some of the services.

A computer-implemented method is performed at a multifunction device with a display and a touch-sensitive surface. The method includes detecting multiple input gestures by a user, beginning with an initial input gesture. For each input gesture after the initial input gesture, the method scrolls information on the display at a respective scrolling speed. The respective scrolling speed is determined based on the respective input gesture movement speed in the input gesture and a movement multiplier. The method determines whether the respective input gesture meets one or more swipe gesture criteria, and determines whether the respective input gesture meets one or more successive gesture criteria. When the input gesture meets the one or more swipe gesture criteria and the one or more successive gesture criteria, the method updates the movement multiplier in accordance with one or more movement multiplier adjustment criteria.

In a left ventricular assist device (LVAD) a rotodynamic blood pump (10) is powered by a brushless DC motor (12). A power supply (14) supplies power to the motor (12). Three feedback channels, one for each of voltage, current, and motor speed lead to a microcontroller or microprocessor (18). The three feedback waveforms are analyzed, and from these waveforms, motor input power, patient heart rate, current pump flow rate, and systemic pressure are determined. The microprocessor (18) then calculates a desired flow rate proportional to the patient heart rate. The microprocessor communicates a new power output to a commutation circuit (16), which regulates power to the motor (12). The pump (10) also includes safety checks that are prioritized over desired pump flow. These include prevention of ventricular suction, low pulsatility, minimum and maximum pump speed, minimum speed-relative pump flow, minimum absolute pump flow, minimum and maximum motor input power.

A method to optimize CRT therapy using ventricular lead motion analysis, either radiographically or with three dimensional electromagnetic mapping, to determine whether focal dyssynchrony is present at baseline, and whether biventricular pacing improves synchronicity and fractional shortening, and if no improvement is evidenced, changing the timing offset, pacing configuration and / or repositioning the ventricular leads to optimize effectiveness of CRT therapy. Various uses of this method include: diagnostic, with temporary leads to determine presence or absence of dyssynchrony and response to pacing; and therapeutic, to guide lead placement and programming during implant of CRT, and to optimize reprogramming of CRT during follow-up.

This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device under conditions in which an access path and the subject anatomy are not aligned.