21769 results about "Medical device" patented technology

The AI-enhanced cellular modeling and simulation platform is a computational system designed to enhance biomedical research and development and personalized medicine and wellness. This platform integrates simulation modeling, machine learning and artificial intelligence, multi-omics data, and sophisticated data fusion and decision-support techniques to create comprehensive models of cellular systems and processes across multiple scales. It enables researchers and clinicians to simulate complex biological interactions, predict disease progression, and design or optimize treatment strategies or medical devices with improved accuracy and efficacy. The system's architecture allows for integration of various components, including real-time data processing, federated learning, and quantum computing enhancements. From personalized drug discovery and cancer therapies to synthetic biology and epidemiological analysis, this platform offers powerful tools for understanding and manipulating cellular systems and bioengineered systems. By bridging the gap between molecular-level interactions between cells and materials and organism-wide effects, it enables significant advancements in healthcare and biological sciences.

The invention relates to the technical field of medical instruments, and discloses a laparoscope and digestive endoscope combined positioning measurement system and method.The method comprises the steps of positioning mark initialization, image feature analysis, instrument path planning, dynamic positioning calibration, operation integrity evaluation and the like. Spatial matching is realized by setting multiple types of positioning marks and utilizing optical reflection signals, noise reduction and feature extraction are performed on endoscope imaging data to generate a measurement area boundary, an operation path is planned in combination with anatomical path information, the tail end position of an instrument is calibrated in real time, and operation integrity is evaluated. The system comprises a positioning module, an analysis module, a correction module and an integration module which are respectively used for realizing the functions of positioning mark setting, image processing and path generation, offset correction and operation evaluation. According to the system, the operation positioning precision and the operation safety are improved, intellectualization and precision of minimally invasive surgery are achieved, and the system is suitable for minimally invasive treatment of digestive system diseases.

A computer-implemented system for personalized health optimization constructs a confidence-weighted personal health knowledge graph (PHKG) from heterogeneous data, including wearable sensors, medical devices, lab results, medication logs, and conversational inputs. A multi-stage causal-inference stack identifies modifiable drivers of outcomes using layered methods (e.g., MI, GAM, Neural Granger, DAG-GNN), and simulates candidate interventions. A recommendation engine ranks lifestyle or pharmacologic actions using a benefit-to-friction score, selecting a personalized intervention aligned with user readiness and clinical safety constraints. Interventions may include a minimum effective dose (MED), optimal level, adaptive low-dose, or behavioral challenge. Optional modules include reinforcement learning for timing adaptation and privacy-preserving on-device inference. The system operates across domains including metabolic, cardiovascular, renal, sleep, stress, and medication response, enabling cross-condition synergy evaluation. The architecture is modular, supports runtime plug-in targets, and adapts in real time with or without continuous clinical oversight, depending on deployment.

The invention discloses a brain-computer hybrid intelligent closed-loop swallowing rehabilitation system for treating dysphagia after stroke, and relates to the field of artificial intelligence medical instruments. The system is composed of a plurality of key modules: an intelligent swallowing brain-computer interface module for accurately identifying a swallowing intention through multi-modal physiological signal acquisition and processing; the intelligent swallowing functional electrical stimulation module is used for finely regulating and controlling stimulation parameters according to the condition of the patient; the AI auxiliary online integrated module is used for realizing non-invasive brain-controlled swallowing and high-precision AI regulation and control; the closed-loop intelligent feedback regulation and control module is used for real-time monitoring, early warning and self-adaptive optimization of electrical stimulation; the cloud platform remote monitoring and data storage module supports remote diagnosis and treatment of doctors; and the man-machine interaction interface display and printing module optimizes doctor-patient interaction. According to the system, a brain-computer interface and FES are combined, a personalized, safe and efficient rehabilitation scheme is provided for a patient based on data driving and an artificial intelligence algorithm, swallowing function recovery can be accelerated, complications are reduced, and the system has great clinical and social values.

An intravascular device includes a tube member. The tube member comprises a distal portion and a proximal portion. Each of the distal portion and the proximal portion of the tube member comprises a plurality of cuts circumferentially extending around a longitudinal axis of the tube member. The plurality of cuts of the distal portion of the tube member comprises a first pitch, a first cut length, and a first uncut length, the plurality of cuts of the proximal portion of the tube member comprises a second pitch, a second cut length, and a second uncut length, and the first pitch is less than the second pitch, the first cut length is greater than the second length, and the first uncut length is less than the second uncut length.

The invention discloses a polypropylene composite material based on rare earth element modification and a preparation method and application thereof, and belongs to the technical field of medical instruments, and the polypropylene composite material comprises the following raw materials in parts by weight: 100 parts of medical grade PP, 3-8 parts of a rare earth organic complex, 5-10 parts of nano-hydroxyapatite, 2-5 parts of a maleic anhydride grafted PP compatilizer and 0.3-0.5 part of an antioxidant, the invention also provides specific preparation steps and application thereof. According to the invention, oxide + salt bimorphological rare earth and an organic ligand are complexed to form a rare earth organic complex, so that the problem of poor dispersity of inorganic rare earth is solved, and meanwhile, the material is endowed with antibacterial and antistatic functions; through a melt blending-in-situ fiber forming process, the rare earth complex forms gradient distribution in a polypropylene matrix, the surface layer is enriched with antibacterial components, and the inner layer is enhanced in mechanical property, so that a low-cost solution with high strength, antibacterial property and biocompatibility is provided for high-end medical instruments, and the market blank is filled.

The invention discloses an endoscope with a built-in grabbing mechanism, and relates to the technical field of medical instruments. According to the technical scheme, the device comprises a clamp assembly, a driving outer pipe and a driving inner wire; the grabbing mechanism further comprises a grabbing mechanism shell, a first moving seat and a second moving seat, wherein the first moving seat and the second moving seat are arranged in the grabbing mechanism shell. The near end of the driving outer tube is connected with the first moving seat, and the near end of the driving inner wire is connected with the second moving seat; when the second moving seat is fixed relative to the grabbing mechanism shell, the first moving seat moves towards the far end direction relative to the grabbing mechanism shell so as to control the clamp assembly to execute the clamping action. According to the invention, the clamping action is carried out while forward extension is carried out, so that high-precision operation is facilitated, and tissues can be accurately clamped; and moreover, the grabbing mechanism is integrated in the endoscope handle, so that accurate single-hand control is facilitated, meanwhile, the clamping action is controlled in a button mode, the human engineering is met, and operation is convenient.

The present invention relates to a novel association or combination of active ingredients useful in the prevention and repair of neuronal damage, both centrally and peripherally. In greater detail, the present invention relates to an association or combination of i) an extract of Gastrodia elata and ii) at least one ingredient selected from the group comprising or, alternatively, consisting of citicoline, L-acetylcarnitine and, preferably, at least one vitamin of group D, and / or mixtures thereof, and / or at least one vitamin of group B, and / or mixtures thereof. Furthermore, the invention also relates to the pharmaceutical compositions and / or compositions for medical devices (Regulation (EU) 2017 / 745) and / or nutraceutical and / or food compositions comprising that association and to their use in therapy, in particular in the protection of the functionality of the nervous system and in the prevention and / or treatment of central and peripheral neuropathies.

The invention relates to a recombinant A type humanized XVII type collagen as well as construction and application thereof, the protein is the humanized XVII type collagen which is composed of an intracellular region, a transmembrane region and an extracellular region, and the amino acid sequence is as shown in SEQ No. 1. The hair follicle repairing agent has the advantages of hair follicle repairing, hair regeneration, good biological activities of cell proliferation, cell adhesion and the like, and can be widely applied to the fields of medicines, medical instruments, biological materials, tissue engineering, cosmetics and the like. The gene sequence of the recombinant A type XVII collagen is 100% identical to the corresponding part of the gene sequence of the recombinant A type XVII collagen, so that the recombinant A type XVII collagen has good hydrophilicity and high activity, and has application potential in the fields of biomedical materials, beauty cosmetics, skin care products and the like.

Labeling and packaging systems include a primary packaging with a top seam and a bottom seam, and enclosing a medical device within its interior cavity. The system further comprises a label system, which consists of a first body with a front surface and a rear surface, extending over a frontal plane and attached to the front surface of the primary packaging. Additionally, the label system includes a first right handle and a first left handle, both attached to the top edge of the first body. A tear line extends longitudinally from the top edge of the first body, and is disposed between the right handle and the left handle. The tear line has a distance (d) that is less than a length (L) of the first body. The tear line is designed to facilitate separation when the right handle is pulled in the opposite direction from the left handle.

The invention discloses a windowing covered stent blood vessel and a delivery system, and belongs to the field of medical instruments, the windowing covered stent blood vessel comprises a covered stent blood vessel main body and a windowing assembly arranged on the covered stent blood vessel main body; wherein the windowing assembly at least comprises a barrel-shaped structural part and a connecting part, and the barrel-shaped structural part is provided with a channel matched with the branch support; the connecting piece is used for connecting the cylindrical structural piece and the covered stent blood vessel main body; the connecting piece is provided with a buffer part, so that the cylindrical structural piece is flexibly connected with the covered stent blood vessel main body; according to the windowing assembly, blocking of the branch support can be effectively avoided, and good wall attaching performance can be provided for the embedded branch support through the buffering part.

The invention relates to the technical field of medical instruments, in particular to a high-precision time interference non-invasive brain deep electrical stimulation method, equipment and system, and solves the problems that two stimulation electrodes are used for each pair of current in traditional time interference-based non-invasive brain deep electrical stimulation, so that the current distribution is relatively dispersed, and the stimulation focusing performance is relatively poor. According to the method, high-precision 4 * 1 electrode configuration is used, two electrodes for applying a stimulation current are changed into a 4 * 1 electrode form, the flowing path of the current is effectively limited, the current is more focused, and the focusing performance of the interference current is further improved. According to the device, high-precision current control is realized through the anti-phase output circuit, the 4 * 1 voltage division circuit, the constant current source module and the impedance detection module; the system supports forward and reverse electrode position optimization, a personalized real finite element head model simulation system based on MRI data is used for guiding practical application, the focusing performance of each pair of current in a target brain region is improved, and therefore the overall stimulation precision in the target brain region is improved.

Provided herein is a tub for holding one or more nests of medical components. The tub includes a bottom wall, a plurality of sidewalls extending upwardly from the bottom wall, and a top flange formed about a top edge of the plurality of sidewalls. Each sidewall is configured as a stepped wall including a lower wall portion and an upper wall portion, with a horizontal ledge formed between the lower wall portion and the upper wall portion that is in parallel with the bottom wall. The tub also includes one or more support members extending up from the bottom wall, with each of the one or more support members having a top surface that is vertically aligned with or vertically below the ledges of the plurality of sidewalls, so as to be positioned to support a bottommost nest of the one or more nests when placed within the tub.

A medical device system includes a stylet with an optical fiber and a console operatively coupled to the stylet. The optical fiber can include an electrically conductive concentric tube configured to transmit electrical signals and a plurality of core fibers within the concentric tube. Each of the plurality of core fibers can include a plurality of sensors, and each the plurality of sensors can be configured to reflect a light signal of a different spectral width based on received incident light and change a characteristic of the reflected light signal based on a condition experienced by the stylet. The console includes one or more processors and a non-transitory computer-readable medium with logic that causes operations including providing an incident light signal to the optical fiber and receiving reflected light signals of different spectral widths of the received incident light by the plurality of sensors.

The invention discloses a medical integrated module type electroacupuncture anesthesia therapeutic apparatus, and belongs to the technical field of medical apparatuses and instruments. A medical integrated module type electroacupuncture anesthesia therapeutic apparatus comprises a signal collecting and monitoring module, a main control module, a parameter self-adaptive adjusting module, a stimulation output module and a safety monitoring unit. The problems that existing current output parameters depend on manual adjustment and doctor experience, an objective quantitative basis is lacked, a real-time physiological monitoring and feedback mechanism is lacked in the treatment process, and current adjustment lags behind the state change of a patient are solved. Through a multi-parameter fusion decision algorithm and a closed-loop real-time feedback mechanism, 'experience-driven open-loop control 'of traditional electro-acupuncture equipment is upgraded to'data-driven closed-loop control', the subjectivity and hysteresis problems of manual adjustment are solved, and treatment safety and individual adaptability are greatly improved through high-precision monitoring and quick response.

A compound, as shown in Formula I, is a multi-heterocyclic compound. It has been verified that the compound provided by this invention integrates a novel compound targeting the calcitonin gene-related peptide (CGRP) based on ephedrine. Upon contact with the skin, due to photoactivated cell biological function regulation and the blocking effect of the multi-heterocyclic compound I structure on serotonin receptors, it achieves therapeutic effects on cutaneous vascular malformations and telangiectasia, improves the effectiveness of phototherapy in improving chronic cutaneous vascular diseases, and promotes skin wound healing.

The invention belongs to the technical field of medical instruments, and particularly relates to a spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system, the spinal epidural ventral side double-wing-shaped stimulation electrode and motion function reconstruction system comprises two wing panels, each wing panel comprises a flexible substrate, the flexible substrate is provided with two bifurcated preset-curvature double-wing structures; the electrode contact array is integrated on the flexible polar plate through a bonding pad; according to the double-wing-shaped flexible substrate, through a double-wing structure with a preset curvature, after being unfolded under the driving of a nickel-titanium alloy framework, the double-wing-shaped flexible substrate accurately covers a spinal cord ventral side and double-side anterior angle motor neuron pool, and the problem that a traditional single-piece / rod-shaped electrode can only cover a back side sensing area and cannot cover a back side sensing area is solved. The ventral motor neuron group cannot be directly activated; a stimulation target spot is transferred to a ventral functional core area from a dorsal non-target area for the first time, and the anatomical suitability bottleneck of motor function reconstruction is solved.

The invention discloses a double-nail type nailing control device and a valve ring repair system, and relates to the technical field of medical instruments, and the double-nail type nailing control device comprises a mounting shell, a rotating structure and a nailing structure; the rotating structure is installed on the installation shell, the nailing structures are arranged on the two sides of the rotating structure correspondingly and axially penetrate through the installation shell, and the nailing structures are in transmission connection with the rotating structure; the double-nail type nailing control device is used for controlling the rotating structure to rotate so as to control the nailing structures on the two sides to axially move at the same time to be nailed into the valve ring tissue. According to the arrangement, the axial movement of the two nailing structures is controlled at the same time through the rotating structure, the operation that two anchors are screwed into the annulus tissue can be synchronously achieved through one-time operation, and the nailing efficiency is improved; and meanwhile, the multiple double-nail type nailing control devices are close to one another in the circumferential direction in the mode that a locking wire assembly in the annulus repair system pulls a locking wire from the two ends at the same time, and annulus tissue contraction is achieved.

This disclosure generally relates to medical devices that include a sensor transmitter assembly that includes a sensor assembly including a sensor module where a first sensor including a first sensor head having at least one first sensor contact pad is combined with a second sensor including a second sensor head having at least one second sensor contact pad. The sensor transmitter assembly also includes a transmitter assembly positioned on a top of the sensor assembly to form a single unit, the transmitter assembly having at least one transmitter contact disposed on a base of the transmitter assembly, where the first sensor contact pad(s) and the second sensor form a connection path with the transmitter contact(s).

The invention relates to the field of medical instruments, and discloses an anesthesia injury monitoring evaluation and management system for pain monitoring and rehabilitation acceleration. Comprising a sensor module configured to collect acupuncture point skin temperature data in a percutaneous acupuncture point electrical stimulation process, current parameter data output by an electrical stimulation device and skin impedance change data in real time; the control module is used for inputting the temperature data, the current parameter data and the skin impedance data which are acquired in real time into a multi-parameter risk assessment model, calculating a real-time risk value and generating a parameter change curve containing a time sequence; when the real-time risk value exceeds a preset safety threshold value, or any single parameter in the parameter change curve reaches a temperature change rate threshold value, an accumulated electrical stimulation energy threshold value or a skin impedance abnormal fluctuation threshold value, triggering a multi-stage early warning signal; according to the early warning level of the early warning module, the output power, the pulse frequency or the action time of the electrical stimulation device is automatically adjusted, or electrical stimulation is forcibly terminated when early warning is performed at the highest level.

The application relates to the field of medical devices, in particular to a repair system capable of accurate positioning, which comprises a delivery catheter, a positioning support arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guide wire, the positioning support is arranged at the distal end of the delivery catheter, the positioning support is provided with a plurality of anchoring points distributed in the circumferential direction, the flexible sleeve is provided with a plurality of connecting points arranged in correspondence with the anchoring points, the guide wire passes through the connecting points and the anchoring points corresponding to the connecting points in sequence, and after the positioning support is released, the anchoring mechanism pushes the flexible sleeve, so that the flexible sleeve cooperates with the guide wire and guides the anchoring mechanism to reach each anchoring point along a predetermined route and complete anchoring; the application not only simplifies the structure of the device, but also realizes accurate guidance.

A controlling system method docking for a mobile patient bed with a medical device. The method may include: obtaining, based on a docking instruction, positioning information of a target; controlling, based on the positioning information of the target, a movement of the mobile patient bed; and in response to determining that the mobile patient bed moves into a docking region of the medical device, controlling the mobile patient bed to dock with the medical device using a first docking structure on the mobile patient bed and a second docking structure on the medical device, wherein the first docking structure and the second docking structure are mechanical connection structures. By adopting the embodiments of the present disclosure, an operator may carry a mobile device to move, and control the movement of the patient bed by continuously changing a position of the mobile device, or may enable the patient bed to obtain an automatically planned path through the positioning information of the medical device and to move along the automatically planned path.

The present invention is directed to enhanced content security mechanisms for containers. Further, the invention is directed to containers comprising these enhanced content security mechanisms. In particular, the containers of the present invention comprising the enhanced content security mechanism of the invention offer advanced anchoring of the contents (e.g., baked goods or sensitive devices such as medical devices) of the container by preventing: shifting, tipping, breaking, crumbling, rolling or other movement of the contents; thus securing the contents and preventing damage to the contents, i.e., preserving the appearance and integrity of contents contained within.

The invention discloses a tumor needle biopsy robot and an image real-time navigation system thereof, and relates to the technical field of medical instruments, and the method comprises the following steps: extracting historical data, and constructing a segmentation model according to the historical data; acquiring a plurality of medical images of the patient, and constructing a three-dimensional model of the patient according to the plurality of medical images; constructing a visual puncture path according to the three-dimensional model; the method comprises the following steps: acquiring optical tracking data, acquiring a needle point position according to the optical tracking data, correcting a puncture path according to the needle point position, acquiring a path point sequence according to a puncture starting point, a target point, a cost function and a graph structure when an optimal path is planned, and continuously adjusting the path through a path optimization algorithm. The path is far away from key tissues such as important blood vessels and nerves, the path is prevented from excessively approaching or directly penetrating through a dangerous area, so that the rationality of optimal path planning is ensured, the precision controllability of the puncture process is enhanced, the puncture path is corrected in real time through the position of the needle tip, and the possibility of the scheme is further improved.

The invention discloses an optic disk atrophy arc image segmentation method based on full supervision, and particularly relates to the technical field of medical equipment, and the method comprises the following steps: S1, multi-scale feature extraction, S2, local-global feature enhancement, S3, adaptive feature fusion, S4, gradient flow optimization, S5, mixing of a loss function, and S6, data enhancement and generalization optimization. According to the method, the long-range dependence of the optic disk and the atrophic arc is globally modeled through the PVTv2 encoder, the detail segmentation precision of the optic disk atrophic arc at the blood vessel crossing and fuzzy boundary is remarkably improved in combination with the multi-scale attention and dilated convolution of the feature enhancement module, cross-level feature fusion is realized with linear complexity based on the Mama decoder, and the accuracy of feature fusion is improved. Efficiency and structure coherence are considered; the weight is balanced by the mixed loss function, and early lesion missing detection is reduced; a data enhancement and residual module enhances the generalization ability of the model, and a high-precision and efficient quantitative analysis tool is integrally provided for early screening of blind eye diseases such as pathological myopia and glaucoma.

The invention discloses a multi-mode implantable sensor and a signal acquisition system, and relates to the technical field of medical instruments, and the multi-mode implantable sensor comprises two layers of flexible substrates which are oppositely arranged; the multi-mode electronic functional layer is located between the two layers of flexible substrates and comprises at least two sensors used for collecting different biological characteristic signals; the flexible substrate has a shape memory capability, so that the multi-mode implantable sensor can be converted from a contraction state to an expansion state. According to the invention, different biological characteristic signals can be monitored at the same time through the same multi-mode implantable sensor; in addition, the multi-mode implantable sensor can also realize form switching based on a flexible substrate with shape memory ability, so that the multi-mode implantable sensor can be implanted through a small-size contraction state to reduce implantation wounds, and can be converted from the contraction state to an expansion state after implantation is completed, so that multi-mode biological characteristic signals can be conveniently acquired.

The invention relates to the technical field of medical instruments, and discloses intravenous infusion puncture angiography glasses equipment and an application method thereof. The equipment comprises an infrared imaging module, an image processing module, a data communication module, a correction early warning module and a display module. The infrared imaging module collects original blood vessel image data, the image processing module generates blood vessel positioning information, the data communication module interacts with a background server, the correction early warning module generates an early warning prompt according to a server instruction, and the display module displays related information in an overlapping mode. By accurately positioning the blood vessel and providing puncture guidance, the equipment improves the success rate of venous transfusion puncture, reduces the pain of a patient, improves the medical working efficiency, reduces the medical cost, guarantees the medical safety, and is suitable for various venous transfusion puncture scenes, especially patients with poor blood vessel conditions.

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Polymeric tubing, for use with catheters or other medical devices, where the polymeric tubing can have regions of customized properties including, but not limited to, durometer, torque control, flexibility, axial strength, stiffness, etc. One variation of the device allows for transitions between regions to be configured such that there can be gradual or customized transitions between various regions such that the structural characteristics differential between the regions are selectively designed. Additional variations include outer layers having a plurality of material sections extending in a spiral direction along the axial length to form a continuous wall of the outer layer. In certain variations, the structural characteristic differential is minimized or eliminated as compared to conventional catheters.