590 results about "Biological body" patented technology

According to the invention, the multi-mode time-frequency domain conversion and the deep learning technology are combined, and a multi-component mixed Raman spectrum unmixing method is developed, so that clinical in-vivo and in-situ detection and disease diagnosis of novel Raman probes, instruments and the like are facilitated. The method comprises the following steps: (1) converting a mixed Raman spectrum from a time domain to a frequency domain by using fast Fourier transform (FFT), discrete cosine transform (DCT) and discrete sine transform (DST), and extracting frequency domain features; (2) extracting multi-scale local time-frequency domain characteristics of the mixed spectrum by using short-time Fourier transform (STFT) and discrete wavelet transform (DWT); (3) carrying out spectral unmixing calculation in each mode in combination with a one-dimensional attention mechanism U-shaped neural network model; and (4) fusing various modal unmixing results by using a meta-learning method, and analyzing the weight of each modal to obtain an accurate unmixing spectrum. Compared with a traditional Raman spectrum analysis method, the Raman spectrum multi-component signal unmixing method based on multi-modal time-frequency domain transformation and deep learning can accurately separate independent Raman signals of different tissue structures and biochemical components in a complex environment in a living body, so that the unmixing accuracy of the Raman spectrum multi-component signal is improved. Therefore, convenience is provided for subsequent disease mechanism analysis and diagnosis. The method provides an innovative and potential solution for in-vivo and in-situ detection analysis and disease diagnosis of medical clinical Raman spectroscopy.

The application provides application of SEBS in implanting a biological electrode base. The biological electrode based on the SEBS base can be implanted in biological tissues, and is used for continuously or discontinuously analyzing physiological parameters of the biological body. Compared with other flexible bases, the SEBS base has the characteristics of being thinner and more flexible, can reduce the interference of body movement on the electrical signal, reduce the volume range of the implanted tissue and reduce the inflammatory reaction, thereby improving the measurement accuracy and long-term stability, is expected to meet more implantation site requirements when used for implanting a sensor, and has a good application prospect.

The invention provides a biological characteristic closed-loop monitoring method, device and equipment based on terahertz signals, and the method comprises the steps: executing closed-loop regulation and control operation based on target biological characteristic information; wherein when the closed-loop regulation and control operation comprises environment self-adaptive regulation and control, the environment self-adaptive regulation and control comprises the steps of monitoring an environment parameter of an environment where the target organism is located, and dynamically adjusting a signal parameter used for transmitting a terahertz signal based on the environment parameter; when the closed-loop regulation and control operation comprises biological feedback regulation and control and it is judged that the target biological characteristic information meets a preset abnormal condition, the biological feedback regulation and control is used for dynamically adjusting communication network resources used for bearing terahertz signals. According to the method, the target biological characteristic information in the terahertz reflection signal and the auxiliary sensing signal is analyzed, traditional equipment does not need to be worn, and the accuracy and convenience of biological characteristic monitoring are improved; the robustness and intelligence of the whole biological characteristic monitoring system are improved through a double closed-loop mechanism of environment adaptive regulation and biological feedback regulation.

A method for detecting the extent of microplastic accumulation in bivalve organisms in extreme deep-sea environments is provided. This method is performed through sampling of biological communities to represent the community structure of that biological bed layer, then morphological characterization statistics are conducted to classify the age stage data of individual bivalves, multivariate factor analysis is used to obtain the individual bivalves with the greatest degree of contribution in each classified age stage, subsequently tissue-specific microplastic extraction is performed, the morphology of seafloor microplastics is restored and streamlined identification of full-size microplastics is considered, carbon-14 dating is used to trace the duration of microplastic adsorption by each individual bivalve, dynamic accumulation curves for seafloor bivalves are constructed by connecting each bivalve's survival duration, and finally this is scaled up to the entire bivalve bed to derive the microplastic accumulation rate and historical accumulation of the entire extreme ecosystem.

A signal acquisition unit (21) acquires a biological signal. An authentication information generation unit (22) generates, based on the biological signal acquired by the signal acquisition unit (21), authentication information that differs depending on the individual of a biological body. A part information generation unit (23) generates, based on the biological signal acquired by the signal acquisition unit (21), part information that differs depending on the part from which the biological signal is acquired even in a single individual. An authentication unit (24) performs authentication based on the authentication information generated by the authentication information generation unit (22) and the part information generated by the part information generation unit (23).

The invention discloses a deep brain targeted stimulation method based on a time-frequency interference technology, and relates to the technical field of nerve regulation, and an application system comprises a plurality of pairs of stimulation electrode modules, a data acquisition module, a data preprocessing module, a time-frequency interference stimulation signal generation module, a central control module and a data storage module. According to the method, a multi-azimuth surrounding layout of multiple pairs of stimulation electrodes is combined with a time-frequency interference technology, so that a high-frequency electric field forms constructive interference in a deep brain target area, and meanwhile, a frequency difference is dynamically adjusted based on different organism state requirements; and a closed-loop control system of data acquisition, preprocessing, state evaluation, parameter adjustment and stimulation application is constructed. The problems that a traditional deep brain stimulation technology is low in targeting precision, poor in state guiding efficiency and insufficient in stimulation system stability are solved, the energy focusing degree is improved to 90% or above, the sleep induction time is shortened to 20-30 minutes, and the method can be widely applied to nerve disease treatment and physiological state improvement.

The invention discloses a composition with a sleep improving function as well as a preparation method and application thereof, and the composition is prepared from the following raw materials in parts by weight: 50-100 parts of acanthopanax root, 30-50 parts of lotus seed, 50-100 parts of spina date seed, 30 parts of lily, 30 parts of longan, 30-50 parts of poria cocos, 30 parts of radix ophiopogonis, 10-30 parts of rehmannia, 10-30 parts of gastrodia elata, 2 parts of glutamic acid, 0.1 part of vitamin B, 0.1 part of vitamin B6 and 0.1 part of gamma-aminobutyric acid. The traditional single target spot limitation is broken through, a synergistic effect system of tonifying the spleen and soothing the nerves-neurotransmitter regulation and control-intestinal brain axis regulation is formed, a buffer solution of pH simulation biological fluid is adopted as a non-organic extraction medium in the process, the ultrasonic cavitation effect and the plasma activation effect are combined, the temperature is controlled in the whole process, and the preparation method is simple and easy to implement. The problems of vortex, uneven extraction, dead volume, solvent residue, active ingredient damage and the like in traditional extraction are fundamentally solved, the composition capable of effectively improving the sleep quality is obtained, and animal model and crowd experiments prove that the composition can effectively improve the sleep quality and achieve a good sleep aiding effect.

The present invention relates to informing surrounding people of biological information of a user in a more popular and understandable manner. A vehicle system (1) includes: a seat (10) as an example of an interior member disposed in a vehicle (C); an ornament (20) provided to the interior member; a winch (23) as an example of an electric device for changing the shape of the ornament (20); a heartbeat sensor (61) and a respiration sensor (62) as one example of sensors for acquiring biological information of a user; and a control unit (50). The control unit (50) changes the shape of the ornament (20) by operating the electric device on the basis of the biological information acquired from the sensor.

The invention relates to an active oxygen concentration control method and a brain-computer interface implant accelerated life test system. The accelerated life test system is used for testing the electrochemical performance of a brain-computer interface implant by using a test solution. The method comprises the following steps: detecting a current feedback current corresponding to a current test solution; obtaining the current active oxygen concentration according to the current feedback current and a preset active oxygen concentration and current relation function; generating a filling parameter according to a concentration difference value between the current active oxygen concentration and a preset active oxygen concentration; and adding a hydrogen peroxide solution into the current test solution according to the filling parameters, so that the current test solution reaches the preset active oxygen concentration. According to the method, the active oxygen environment generated by immune reaction in a living body can be simulated through the test solution, the active oxygen concentration in the test solution can be precisely regulated and controlled, and the accuracy of the test result of the brain-computer interface implant is improved.

A user requests validation of a human biometric profile to access a bio-origin validation engine (OVE) with a classification database for all types of biological organisms using biometric signals from all type of sensors and devices such as wearables, environmental and peripherals. The bio-origin components are comprised of an OVE validator system, a biological classification system, an intelligent network interface, validated objects, and a service bridge. A validation engine provides access to a secured network of validated users and systems components. The service bridge provides a platform for validated users use of dynamic biometric signals to augment intelligent services outcome and output. Users of the service bridge biometric use metrics are recorded and logged to validate and issue a certificate of ownership and authenticity. The outcome or output is delivered to a bio-origin validated machine readable encoded content with terms and conditions of distribution and use.

The present invention relates to a device (10) for vibrating aquariums (18) intended to house living organisms in order to study their sensitivity and response to vibrations. The device comprises a base (12), a frame (14) arranged above the base (12) to form a workspace (24) between the base (12) and the frame (14), an armature (28) fixed to the base (12) and supporting the frame (14), a support (16) placed in the workspace (24) and intended to hold at least one aquarium (18), and a vibrating module (64) comprising a housing (66) mounted on the frame (14) and an end (68) fixed to the support (16). The support (16) is carried by the frame (14) by means of at least one suspension element (40) capable of elastic deformation. Figure for the abstract: 2

The invention relates to the technical field of minimally invasive treatment surgical medical instruments, and discloses a magnetic anchoring traction device, which comprises an outer magnetic mechanism, an inner magnetic mechanism, an inner magnetic mechanism, a traction mechanism, a traction mechanism and a traction mechanism, and is characterized in that the outer magnetic mechanism is configured to be arranged outside an organism and comprises an outer magnet with magnetism or capable of generating magnetism; the inner attraction body is made of a material which does not have magnetism and can be magnetized close to the magnet, the inner attraction body is configured to be arranged inside a living body, and the upper end of the inner attraction body is used for facing the lower end of an outer magnetic mechanism located outside the living body, so that the inner attraction body and the outer magnet attract each other; and the upper end of the tractor is connected with the lower end of the inner aspirator, and the lower end of the tractor comprises a connecting part and is used for dragging tissues or organs in a living body or is connected with an in-vivo catheter. By means of the internal attraction body which is not magnetic and is made of a material which is close to the magnet and can be magnetized, the influence of magnetic force on an instrument in a living body can be reduced, high-temperature disinfection of the internal attraction body is facilitated, and therefore the safety of minimally invasive treatment surgery is improved.

This invention discloses a rapid mass spectrometry method and kit for the simultaneous detection of multiple components in body fluids, belonging to the field of biological detection and identification technology. It can rapidly detect trace compounds such as drugs and biomarkers in complex biological samples. This kit mainly utilizes loaded functional materials to achieve extraction and enrichment of target analytes and is equipped with a quick connector for coupling with a detector to achieve rapid detection. Compared with traditional methods, the significant advantages of the method established by this kit are that it does not require complex sample pretreatment, allows for micro-quantitative sampling, requires small sample volumes, facilitates convenient storage of biological samples, is easy to operate, does not require specialized technical personnel, and enables rapid on-site detection when coupled with portable mass spectrometry. This kit has been successfully used for the detection of quinine, procainamide hydrochloride, atenolol, and nortriptyline in complex samples such as blood and serum, and has significant clinical and economic value.

The invention relates to a microfluidic component used for electrical impedance measurement through a biological object (O), said microfluidic component comprising: A support in which is made a main microfluidic channel (C_1) defining a path for the circulation of a fluid containing the biological object (O), A trapping device positioned in the main microfluidic channel (C_1) on the circulation path of said biological object, At least one first electrode and a second electrode intended to be each set at a distinct electrical potential, in order to perform said impedance measurement, Said trapping device being composed of at least one first central pillar (P_1) and a second central pillar (P_2) positioned inside the microfluidic channel, The first central pillar being configured to form the first electrode and the second central pillar being configured to form the second electrode.Figure to be published with the abbreviation: Figure 2.

The present invention, among other things, provides technologies for detecting and / or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and / or DNA loci.

The invention discloses a system and a method for interfering autonomous consciousness in a dream by using an external environment, and relates to the technical field of mental interference equipment. The system comprises an experiment table arranged in an independent environment, a temperature control mechanism is arranged on the periphery of the experiment table, and the temperature control mechanism regulates and controls the temperature of the independent environment in a partitioned mode; the air flowing mechanism adjusts the air flow speed in multiple directions and multiple gears; the sound control mechanism is used for adjusting the direction and the volume of the played sound source; one or more of the temperature control mechanism, the air flow mechanism and the sound control mechanism physically interfere with the living body after the living body falls asleep; and the control system is used for controlling the operation of all the mechanisms and regulating and controlling the cooperation among all the mechanisms. The system can guide and interfere the dream of the living body through the physical interference means of each mechanism, so that the specific treatment, training or research purpose is achieved, and the system has wide application prospects.

This invention discloses a numerical characterization method for gas explosion damage based on in vivo biological damage correction, belonging to the interdisciplinary field of explosion mechanics and biomedicine. The method first acquires multi-dimensional damage data of organisms in gas explosion experiments, constructs a fluid-structure interaction numerical model of the gas explosion flow field in the tunnel and a biomimetic finite element model of the organism, solves the model using an improved arbitrary Lagrange-Euler algorithm, and extracts dynamic biomechanical response parameters. A quantitative correlation between mechanical response and damage level is established through a multi-objective collaborative correction model and an ordered Probit correction model. After iterative optimization, a high-confidence gas explosion-induced biological damage prediction model is output. This invention forms a complete closed loop of simulation-experiment-correction, which can accurately characterize gas explosion biological damage, providing technical support for research on explosion injury mechanisms, assessment of protective effectiveness, and clinical diagnosis and treatment.

The invention relates to the technical field of monitoring and sound control, in particular to a repelling device which comprises a mounting mechanism arranged on a wheel and / or the side of the wheel. The detector is used for detecting an organism close to the wheel, and in a preset detection range, the detector can detect the organism and send out a detection signal; a controller capable of outputting a control signal according to the detected signal; the loudspeaker can give out preset noise according to the control signal, and the noise is used for interfering and stimulating an organism close to the wheel within a preset loudspeaking range so as to repel the organism; and the loudspeaker is mounted on the mounting mechanism. According to the technical scheme, noise interference and stimulation can be carried out on the living body entering the preset detection range, so that expelling of the living body is achieved, meanwhile, when the living body leaves the preset detection range, noise output is stopped, and harm to physical and psychological health of nearby people caused by long-time and large-range noise is avoided.

The present invention generates an image of a character using a machine learning model. This image processing system comprises: an information acquisition unit that acquires character information for designating a character and a living organism image being an image of a living organism including a face; and an image generation unit that, by inputting input information to an image generation model using the character information and the living organism image, causes the image generation model to generate a decorative character image. The decorative character image is an image showing a decorative character being a character to which a decoration showing the face of the living organism shown in the living organism image is applied. The image generation model is trained so as to generate, on the basis of the inputted information, an image to which the decoration showing the face of the living organism shown in the living organism image is applied.

Described herein are novel methods, reusable frameworks, and systems for producing building materials, structural materials, and concretes. The methods include adding a plurality of aggregate particles to a framework, thereby forming a framed plurality of aggregate particles, flowing a first fluid comprising cementation reagents through the framed plurality of aggregate particles or flowing the first fluid through the framed plurality of aggregate particles at a pressure greater than atmospheric pressure, wherein the fluid is introduced to the framework from a direction such that the flow operates against the force of gravity, and reacting the cementation reagents with a biological organism and / or an enzyme comprised within the fluid or within the framed plurality of aggregate particles for a sufficient time to consolidate the framed plurality of aggregate particles, thereby forming the construction material.

Fluid reservoir (113; 213; 313) for an aspiration line (107) of a medical system, wherein the aspiration line (107) serves to aspirate a fluid from a surgical site on a living being by means of a fluid pump of the medical system in a suction direction, comprising: - a shell (214; 314) enclosing a chamber (219; 319) designed to hold a fluid; - a separating element (215; 315) that divides the chamber (219; 319) into a first sub-chamber (219a; 319a) and a second sub-chamber (219b; 319b); - a first fluid connection (220; 320) designed to fluidically connect the first subchamber (219a; 319a) to an outer surface of the shell (214; 314), and designed to be connected to a first part (107a) of the aspiration line (107) to be connected to the fluid pump; - a second fluid port (222; 322) designed to fluidically connect the second subchamber (219b; 319b) to the outer surface of the shell (214; 314), and designed to be connected to a second part (107b) of the aspiration line (107) to be directed towards the surgical site; and - a backflow preventer that the separating element (215; 315) has to fluidically connect the first subchamber (219a; 319a) with the second subchamber (219b; 319b), wherein the backflow preventer is designed to prevent a flow of fluid from the first subchamber (219a; 319a) into the second subchamber (219b, 319b) in the opposite direction to the suction direction, and wherein the separating element is a flexible separating element (215; 315), and the flexible separating element (215; 315) is designed in such a way as to achieve a pumping effect of the fluid reservoir (113; 213; 313) in the second subchamber (219b; 319b) when the flexible separating element (215; 315) is deformed by a certain positive pressure difference between the first subchamber (219a; 319a) and the second subchamber (219b; 319b), which enables the conveyance of a certain fluid delivery volume, characterized by the fact that the specific fluid flow volume is chosen depending on the type of operation performed on a living being.

Methods and systems for automating surgical procedures in model organisms. The system includes a user input panel, a trained computer vision system, a server, and articulated robotic arm. The system may further include an analytical scale, an anesthesia chamber, a tube labeling system, a tissue freezing system, and a biohazard waste disposal system. The computer vision system communicates with the robotic arm to coordinate tissue collections and common research procedures such as injections via recognition models related to detection, identification, localization, and classification. The central server provides rapid synchronization of data between the local machine and a cloud account system for real-time data analytics. The anesthesia chamber provides standardized administration of anesthesia, the sample labeling system provides 2D barcoded labels according to user input, and the tissue freezing and waste disposal systems enable storage of samples and removal of carcasses following tissue collection, fully automating the necropsy.

Disclosed herein are viewing systems configured for viewing an image of a biological object illuminated with light and a viewing device (e.g., loupes, glasses, etc.) and methods for operation thereof. The viewing device comprises a plurality of viewing modes: a white light mode, a fluorescent light mode, and an overlay mode, and a shutter that opens and closes in accordance with the viewing mode. An overlay image is an image of the biological object when the biological object is illuminated with both white light and fluorescent light, causing the overlay image to be an overlay of the white light image and the fluorescent light image. The disclosed systems and methods allow a user (e.g., a surgeon, medical staff, etc.) to preserve the ergonomics offered by eyewear while providing fluorescent viewing capabilities, particularly with visible fluorescent dyes.

The present disclosure addresses the problem of improving human detection accuracy. A human detection system (100) is provided with a scattering point calculation unit (221), a processing unit (222), a position output unit (223), a body movement detection unit (224), a biological signal detection unit (225), and a presence / absence determination unit (226). A scattering point calculation unit (221) calculates a plurality of scattering points at which radio waves have been reflected. The processing unit (222) outputs point group data obtained by clustering the plurality of scattering points and the center-of-gravity position of the point group data. The position output unit (223) outputs the center-of-gravity position as the presence position of the person when the center-of-gravity position is included in the predetermined region. The body movement detection unit (224) detects the magnitude of the body movement of the person when the position output unit (223) outputs the presence position of the person. A biological signal detection unit (225) detects a biological signal of the person when the position output unit (223) outputs the presence position of the person. The presence / absence determination unit (226) determines that a person is present in the predetermined region when the magnitude of the body movement of the person is greater than a threshold value set for the magnitude of the body movement of the person and / or the biological signal is greater than a threshold value set for the biological signal.

The invention relates to the technical field of biological medicine, and relates to a polypeptide in targeted combination with SOX2 protein and application thereof, the polypeptide has an amino acid sequence as shown in SEQ ID NO.1, or has at least 85%, 90%, 95% or more than 99% of sequence identity with the amino acid sequence; the polypeptide inhibits phase separation of SOX2, liquid drops formed by phase separation of SOX2 can be avoided, then the situation that the liquid drops wrap chemotherapeutic drugs, influence the curative effect of the chemotherapeutic drugs and cause tolerance of tumor cells to the chemotherapeutic drugs is avoided, and the polypeptide does not influence the transcription activation function of SOX2 serving as a transcription factor; the polypeptide can inhibit the phase separation of the SOX2, so that the regulation of normal physiological functions, such as high expression in organs such as eyes of a human body, of the SOX2 as a transcription factor is not influenced, and therefore, the polypeptide disclosed by the invention can reverse chemotherapy drug resistance of tumors such as squamous carcinoma by inhibiting the phase separation of the SOX2, can be used for adjuvant therapy of the tumors such as squamous carcinoma, and has no obvious toxic or side effect on each organ of an organism.

The present invention relates to a method for the expression of genes belonging to different organisms (bacteria, fungi, plants, animals and humans) in P. pastoris cells, comprising the following processing steps;i. Transfer of the gene to be expressed into the plasmid carrying the alcohol oxidase 1 (AOX1) promoterii. Cloning of the plasmid carrying the geneiii. Transfer of the recombinant plasmid carrying the AOX1 promoter and gene into the expression hostiv. Induction of the AOX1 promoter with farnesol and consequent expression of the heterologous gene.The present invention will be used in the field of recombinant protein production.

1. The name of the design product: surgical needle head (hernia surgical needle). 2. The use of the design product: the overall use of the product is for implantation into the human body, and the needle head is used to send in the ligation line, withdraw the ligation line, and maintain, pull and cut the biological tissue. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1. 5. Other circumstances that need to be explained: the design product requests partial design protection, the solid line represents the part that is requested to be protected, and the dashed line represents the part that is not requested to be protected; the A part enlarged view is a partial enlarged view of part A in the front view; the B part enlarged view is a partial enlarged view of part B in the bottom view; the C part enlarged view is a partial enlarged view of part C in perspective view 1.

Systems and methods for sensing vibrational absorption induced photothermal effect via a visible light source. A Mid-infrared photothermal probe (MI-PTP, or MIP) approach achieves 10 mM detection sensitivity and sub-micron lateral spatial resolution. Such performance exceeds the diffraction limit of infrared microscopy and allows label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells can be visualized. MIP imaging technology may enable applications from monitoring metabolic activities to high-resolution mapping of drug molecules in living systems, which are beyond the reach of current infrared microscopy.

A biological body detection device is provided with at least one radar and an ECU. The radar is mounted in a vehicle, transmits a pulse wave of a predetermined frequency, and receives a reflected wave of the pulse wave. The radar performs a plurality of times of transmission and reception at predetermined intervals. The reception time of the reflected wave is longer than the time corresponding to the distance between the radar and the position farthest from the radar in the end portion of the vehicle. The ECU detects the presence or absence of a living body on the basis of a reception signal during multiple transmissions and receptions.

An information processing system according to one embodiment of the present disclosure is equipped with: an acquisition unit for acquiring first biological information, which is information pertaining to the living body of a user and is retrieved from a user terminal in which certification information is installed, which is information pertaining to a public certificate of the user, and second biological information which is information pertaining to the living body of the user and is associated with the certification information; an authentication unit for subjecting the user to biological authentication on the basis of the first biological information and the second biological information; a registration unit for registering the information pertaining to the user which was authenticated by the biological authentication; and a service provision unit which provides a service to the user according to a request from the user terminal when information pertaining to the user is registered.