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479 results about "Biological membrane" patented technology

A biological membrane or biomembrane is an enclosing or separating membrane that acts as a selectively permeable barrier within living things. Biological membranes, in the form of eukaryotic cell membranes, consist of a phospholipid bilayer with embedded, integral and peripheral proteins used in communication and transportation of chemicals and ions. The bulk of lipid in a cell membrane provides a fluid matrix for proteins to rotate and laterally diffuse for physiological functioning. Proteins are adapted to high membrane fluidity environment of lipid bilayer with the presence of an annular lipid shell, consisting of lipid molecules bound tightly to surface of integral membrane proteins. The cell membranes are different from the isolating tissues formed by layers of cells, such as mucous membranes, basement membranes, and serous membranes.

Continuous flow AOA whole-course anaerobic ammonia oxidation self-enrichment enhanced denitrification system and method

The invention relates to a continuous flow AOA whole-course anaerobic ammonia oxidation self-enrichment enhanced denitrification system and method, and the system comprises a front anoxic tank, an aerobic tank and a rear anoxic tank which are connected in series, and is filled with a biological filler; the monitoring aeration device comprises an ammonia nitrogen detector and an aeration unit which are connected with the aerobic tank; the reflux device is used for communicating a reflux outlet of the rear anoxic tank with water distribution of the front anoxic tank; and the PID control unit is connected with the monitoring aeration device, the backwashing control valve and the reflux device. The method comprises the following steps: sewage flows into the front anoxic tank, the aerobic tank and the rear anoxic tank; regulating and controlling the reflux ratio to domesticate the biological membrane of the aerobic tank; the ammonia nitrogen concentration of effluent of the aerobic tank is detected in real time through an ammonia nitrogen detector, and the PI D control unit dynamically adjusts the aeration rate of the aerobic tank according to the ammonia nitrogen concentration value and a preset target value, so that the aerobic tank and the rear anoxic tank form an anaerobic ammonium oxidation bacteria self-enrichment environment; the backflow device is used for enabling effluent of the rear anoxic tank to flow back to the front anoxic tank according to a preset proportion, so as to form a whole-process anaerobic ammonia oxidation self-enrichment environment.
Owner:SDIC XINKAI WATER ENVIRONMENT INVESTMENT CO LTD +1

Ultrasonic water treatment equipment control method and system based on variable-frequency vibration waves

The invention relates to the technical field of water treatment equipment, in particular to an ultrasonic water treatment equipment control method and system based on variable-frequency vibration waves. According to the method, based on preset fluid working condition parameters, ultrasonic frequency conversion vibration wave signals covering multiple frequency bands are dynamically generated, and a vibrator array is driven to generate a composite sound field; a cavitation effect and an activation effect are synchronously excited in a fluid medium through variable-frequency vibration wave signals, so that physical form depolymerization and surface charge distribution change of scale forming substances occur; a shearing effect is formed on a fluid-pipe wall boundary layer, an attached state biological membrane structure is stripped, and the microscopic binding force of a crystallized scale body is loosened; monitoring the dispersion degree of scale-forming substances in the fluid and the state of a boundary layer, and adjusting the frequency band combination and energy distribution of variable-frequency vibration waves to maintain scale inhibition; and continuously optimizing the frequency conversion strategy and the sound field intensity according to the feedback data of the scale inhibition maintenance state. Through intelligent multi-band frequency conversion control of the ultrasonic water treatment equipment, efficient and environment-friendly water treatment and scale prevention effects are realized.
Owner:JIANGSU HUIREN NEW ENERGY TECH CO LTD

Three-dimensional bullfrog breeding system and precise feeding control method

The invention discloses a bullfrog three-dimensional breeding system and an accurate feeding control method, and the bullfrog three-dimensional breeding system is characterized in that the bullfrog three-dimensional breeding system comprises a modular breeding unit, a gradient water level adjusting device and an interlayer isolation water circulation system, the three-step type three-dimensional framework is divided into a bottom layer tadpole pond, a middle layer froglet net cage and a top layer adult frog breeding bin, a control module is installed on each layer, and anti-escape assemblies are installed on the middle layer froglet net cage and the top layer adult frog breeding bin; the gradient water level adjusting device comprises a bionic step and a water level sensor which are arranged and installed, and the water level gradient adjusting and behavior inducing functions are achieved through engineering design. The interlayer isolation water circulation system comprises a distributed sensor, a UV sterilization and biological membrane filtration dual purification assembly and an adjustable air curtain, the adjustable air curtain forms a directional barrier between different layers of the three-dimensional culture system by dynamically regulating and controlling airflow, and independent environmental parameters of each layer are maintained.
Owner:JINING RUNTANG ECOLOGICAL AGRI TECH CO LTD

Injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and preparation method of injectable hydrogel

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.
Owner:JILIN UNIVERSITY

Nano-drug based on atomic layer deposition as well as preparation method and application of nano-drug

The invention provides a nano-drug based on atomic layer deposition and a preparation method of the nano-drug, mesoporous silica is taken as a carrier, bimetallic nanoparticles are precisely deposited through ALD, and chemotherapeutic drugs and antibacterial components are loaded by combining amination and targeted PEG modification, so that the following functions are realized: (1) H2O2 in a tumor microenvironment is catalyzed to generate reactive oxygen species (ROS); removing fusobacterium nucleatum and damaging a biological membrane of the fusobacterium nucleatum; (2) GSH is consumed through Fenton reaction, and tumor drug resistance is reversed; and (3) the drug is released in pH response, and tumor cells are accurately killed. The invention further provides application of the nano-drug based on atomic layer deposition in treatment of related drug-resistant colorectal cancer induced by fusobacterium nucleatum, the process is controllable, the biocompatibility is excellent, the treatment effect on the drug-resistant colorectal cancer is remarkably improved, and the nano-drug has wide clinical application prospects.
Owner:SHANXI BETHUNE HOSPITAL (SHANXI ACAD OF MEDICAL SCI SHANXI HOSPITAL OF TONGJI HOSPITAL AFFILIATED TO TONGJI MEDICAL COLLEGE OF HUAZHONG UNIV OF SCI & TECH SHANXI MEDICAL UNIV THIRD HOSPITAL SHANXI MEDICAL UNIV THIRD CLINICAL COLLEGE OF MEDICINE)

Fe / C load-based membrane module, PN / A-MABR autotrophic nitrogen removal device, preparation method and sewage treatment method

The invention discloses a Fe / C loaded membrane module, a PN / A-MABR autotrophic nitrogen removal device, a preparation method and a sewage treatment method, and belongs to the technical field of sewage treatment. According to the invention, the problem that the treatment effect is influenced by NO3 <->-N accumulation in the existing membrane aeration coupling partial nitrification-anaerobic ammonia oxidation process is solved. Comprising a frame and a membrane body attached to the outer portion of the frame, the membrane body comprises a hydrophobic organic membrane layer, an iron-carbon material layer and a biological membrane layer which are sequentially arranged, and the hydrophobic organic membrane layer is attached to the outer portion of the frame. The iron-carbon material is added between the hydrophobic organic membrane layer and the biological membrane layer, the iron-carbon micro-electrolysis process is coupled with the dissimilatory process of nitrate generated by microbial metabolism, the removal of NO3 <->-N generated by anaerobic ammonia oxidation is enhanced, and the total nitrogen removal efficiency is improved.
Owner:HARBIN INST OF TECH

Self-cleaning composite piezoelectric ceramic membrane as well as preparation method and application thereof

The invention discloses a self-cleaning composite piezoelectric ceramic membrane as well as a preparation method and application thereof, and belongs to the field of composite ceramic membranes. The technical problem that an existing ceramic membrane separation technology is poor in biomembrane pollution resisting effect is solved. According to the preparation method, the barium titanate ceramic membrane is firstly prepared to serve as the base membrane, then the copper oxide one-dimensional nanostructure is loaded on the piezoelectric ceramic substrate, and the base membrane has a large membrane surface area and can be combined with more catalysts, so that more active sites are provided for catalytic reaction; according to the composite membrane, the hydrophilicity, the anti-pollution performance and the piezoelectric catalysis self-cleaning performance of the membrane are remarkably improved, and pollutants in water can be quickly and effectively separated, so that the flux and the anti-pollution performance of the membrane are improved.
Owner:HARBIN INST OF TECH

Recombinant chicken antibacterial peptide aiming at drug-resistant staphylococcus aureus

The invention provides a recombinant chicken antibacterial peptide aiming at drug-resistant staphylococcus aureus, and belongs to the technical field of veterinarians. The recombinant chicken antibacterial peptide is expressed through genetic engineering recombinant escherichia coli. Three natural chicken antibacterial peptide active regions are fused, and two disulfide bonds are introduced to stabilize the structure of the recombinant chicken antibacterial peptide and enhance the affinity of the recombinant chicken antibacterial peptide to staphylococcus aureus outer membrane protein. The minimum inhibitory concentration of the recombinant chicken antibacterial peptide to the drug-resistant staphylococcus aureus is obviously lower than that of three natural chicken antibacterial peptides, and the formation of a biomembrane of a USA300 strain of the drug-resistant staphylococcus aureus can be thoroughly inhibited when the minimum inhibitory concentration is 8 mu g / mL. The recombinant chicken antibacterial peptide has a good antibacterial effect on different drug-resistant staphylococcus aureus separated from a chicken house, and can effectively solve the infection problem of the drug-resistant staphylococcus aureus in the chicken house.
Owner:JILIN ZHENGYE BIOLOGICAL PROD

Chinese herbal medicine and marine extract combined antibacterial and anti-inflammatory pharmaceutical composition

The invention relates to the field of pharmacy, and discloses a Chinese herbal medicine and marine extract combined antibacterial and anti-inflammatory pharmaceutical composition which comprises the following components in parts by weight: 5-10 parts of baicalin extract; 3 to 7 parts of an andrographolide extract; 2-5 parts of sulfated brown algae polysaccharide; 0.2 to 1 part of sponge extract; wherein the baicalin extract is derived from roots of scutellaria baicalensis and is obtained by extracting with an ethanol-water mixed solvent; the andrographolide extract is derived from the whole herb of andrographis paniculata and is obtained by extracting with an ethanol-water mixed solvent; the sulfated fucoidan is derived from fucoidan and is prepared by enzymolysis and alcohol precipitation methods; the sponge extract is derived from sponge and is obtained by organic solvent extraction, separation and purification. By adopting the technical scheme of synergistically compounding the Chinese herbal medicine active ingredients and the marine extract, the technical effects of destroying a biological membrane barrier and removing stubborn infection lesions in treatment of bacterial vaginitis, candida vaginitis associated biological membrane infection and cervicitis are achieved.
Owner:ZHENGZHOU LIFE ORIGIN TECHNOLOGY CO LTD

Preparation method of photo-thermal-MMP dual-response matrix hydrogel and application of photo-thermal-MMP dual-response matrix hydrogel in diabetic wound repair

The invention discloses a preparation method of photo-thermal-MMP dual-response matrix hydrogel and application of the photo-thermal-MMP dual-response matrix hydrogel in diabetic wound repair, and belongs to the technical field of biological medicine. According to the present invention, the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is composed of an amnion source photo-crosslinked matrix hydrogel, curcumin-loaded ZIF-8 nanoparticles and MMP2 peptide modified polydopamine, and the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is obtained; the ZIF-8 nanoparticles decline in an acid environment to release zinc ions, destroy bacterial cell membranes, enhance the permeability of a biological membrane and cooperatively kill drug-resistant bacteria in combination with a photothermal effect, Cur is loaded through ZIF-8 to form Cur-coated ZIF-8, then a Cur-coated ZIF-8-coated MMPDA / dAMG double-drug-loading system is constructed through an MMPDA medium, and a photothermal antibacterial, anti-inflammatory and regeneration-promoting multi-mode therapy is formed for a wound surface in the acid environment. Therefore, wound healing is accelerated.
Owner:YANGZHOU FIRST PEOPLES HOSPITAL

Device and process for treating pharmaceutical wastewater by internal electrolysis method

The invention discloses a device and process for treating pharmaceutical wastewater through an internal electrolysis method. The device comprises a pretreatment unit, an internal electrolysis reaction unit, a precipitation separation unit, a pH adjusting unit and a control system which are sequentially connected. The internal electrolytic reaction unit comprises a reaction tower body, the top of the reaction tower body is provided with a water inlet, and the bottom is provided with a water outlet; a supporting layer, an iron-carbon micro-electrolysis filler layer, a catalytic oxidation layer and a biological membrane layer are sequentially arranged in the reaction tower body from bottom to top, the iron-carbon micro-electrolysis filler layer comprises an iron-carbon composite filler, and the mass ratio of iron to carbon in the iron-carbon composite filler is (1: 1)-(3: 1). The internal electrolysis reaction unit with a multi-level filling structure is adopted, iron-carbon micro-electrolysis, catalytic oxidation and biodegradation are organically combined to form a synergistic effect, the removal efficiency of refractory organics in the pharmaceutical wastewater is remarkably improved, and the COD removal rate can reach 80% or above.
Owner:JIANGSU RUISHENG WATER TREATMENT

Application of NSC348884 in preparation of antibacterial drugs

The invention discloses an application of NSC348884 in preparation of an antibacterial drug, the bacteria of the NSC348884 are gram-negative bacteria or drug-resistant gram-negative bacteria, and the gram-negative bacteria are acinetobacter baumannii, escherichia coli, pseudomonas aeruginosa or klebsiella pneumoniae; based on an antibacterial drug high-throughput screening technology, it is found from 1280 small molecule compounds that the benzimidazole compound NSC348884 has direct bacteriostasis and sterilization effects on gram-negative bacteria and drug-resistant gram-negative bacteria, and no drug resistance is generated after the benzimidazole compound NSC348884 is continuously applied for 14 days. Further research shows that NSC348884 can interfere with lipid synthesis of gram-negative bacterium cell membranes, inhibit formation of biological membranes and induce lipid metabolism disorder, so that bacteriostatic and bactericidal effects are achieved. In addition, the NSC348884 can also enhance the sensitivity of the drug-resistant bacteria to the imipenem and the polymyxin B.
Owner:THE SECOND HOSPITAL OF DALIAN MEDICAL UNIV

Foleon tooth healing targeting nano preparation and preparation process thereof

The invention discloses a frontalon tooth healing targeting nano preparation and a preparation process thereof, belongs to the technical field of nano medicines, and aims to solve the problems that the natural regeneration capacity of teeth is limited and the combination of ethnic drugs and modern biotechnology is caused due to the lack of a targeting inhibition means for USAG-1. Comprising an anti-USAG-1 monoclonal antibody, ethnic drug components and a nano-carrier, the anti-USAG-1 monoclonal antibody is connected to the surface of the nano-carrier through covalent bonds, the ethnic drug components are loaded in the nano-carrier through physical action, and the nano-carrier is a polylactic acid-glycolic acid copolymer or chitosan; the anti-USAG-1 monoclonal antibody is used as a targeting ligand, is high in targeting property, can accurately reach a tooth focus, improves the drug utilization rate, enhances the curative effect, integrates multiple ethnic drug components, exerts a synergistic effect, can increase the contact area between the ethnic drug components and a biological membrane, promotes the absorption and transport of the drug, and improves the bioavailability of the drug. And the medicine can better play a treatment role.
Owner:宝阳

Preparation method of degradable bactericide for oil field

The invention relates to the technical field of sewage treatment, in particular to a preparation method of a degradable bactericide for an oil field. According to the invention, a hydroxypropyl guanidine gum-polycaprolactone-ethylenediamine fragment copolymer is taken as a carrier, a methylisothiazolinone quaternary ammonium salt (Q-MIT) bactericide is loaded, and the degradable bactericide for the oil field is obtained by cooperating with a dodecyl ethyl sulfide (TC-SE) bactericide and combining with sodium polyaspartate. A carrier forms a hydrogen bond with a polar group on the surface of a biological membrane through a hydroxypropyl guanidine gum main chain to realize targeted anchoring, a polycaprolactone branched chain encapsulates Q-MIT through a hydrophobic effect, primary amino groups of ethylenediamine are introduced to form a pH sensitive Schiff base bond with Q-MIT, and the primary amino groups and adipic dihydrazide form a thermal response hydrazide bond to construct a dual dynamic covalent bond, so that controlled release of Q-MIT is realized, and the biomembrane is prepared. And moreover, the components of the whole system are connected through degradable chemical bonds, so that the environmental protection property and sustainability of oil field operation are guaranteed.
Owner:东营江源化工有限公司

Bacteriostatic bentonite cat litter and preparation method thereof

The invention relates to bacteriostatic bentonite cat litter and a preparation method thereof, and belongs to the technical field of pet supplies. The bacteriostatic bentonite cat litter sequentially comprises a sodium bentonite matrix embedded with a bacteriostatic agent, a metal oxide layer and a biological membrane layer from inside to outside, the sodium bentonite matrix is obtained by mixing and aging bentonite and a sodium modifying agent in a solvent. When the biological membrane is in contact with excrement, the outer-layer biological membrane preferentially blocks liquid permeation, the middle-layer nano ZnO still generates active oxygen in a weak light environment, and the inner-layer Ag < + >-loaded zeolite slowly releases and inhibits bacteria, so that the antibacterial persistence can be improved. The bacteriostatic bentonite cat litter disclosed by the invention is remarkable in deodorization and antibacterial effects, does not stick to hands when being used, does not generate dust, and has relatively strong caking performance.
Owner:SUZHOU GUOJIAN HUITOU NEW MINERAL MATERIALS CO LTD

Iron oxide red wastewater treatment system and method for coupling anaerobic ammonia oxidation with AI prediction

The invention relates to the technical field of sewage treatment, particularly discloses an iron oxide red wastewater treatment system and treatment method based on anaerobic ammonia oxidation coupled AI prediction, and solves the problems of insufficient prediction capability and high operation cost in the prior art. The system comprises a sewage treatment module and an AI control module, wherein the sewage treatment module adopts an integrated biofilm process anaerobic ammonia oxidation system, is equipped with a sensing equipment group to detect water quality parameters, and controls the equipment group to execute instructions; the AI control module receives water quality data through a real-time data interface, generates feature data in combination with a production plan and a scheduling table, predicts water quality by using a GRU-QR model and outputs an advanced control instruction, and then dynamically optimizes the model and triggers compensation control according to actually measured data to form double closed-loop control. The system has the advantages of stable effluent ammonia nitrogen, high efficiency, improvement of regulation and control precision, reduction of medicament dosage and the like, and can effectively reduce the cost and realize high-intelligence control.
Owner:FOSHAN HUAERAN BIOTECH CO LTD

Process for treating pear vinegar production wastewater

The invention provides a pear vinegar production wastewater treatment process, which comprises a primary treatment box, the top of the primary treatment box is rotatably provided with a top plate, the bottom of the primary treatment box is fixedly provided with six groups of partition plates in equidistant circle center symmetry, the tops of the partition plates are rotatably provided with a first turntable, and a filter assembly is arranged between the first turntable and the top plate; the filtering assembly comprises a filtering frame, the filtering frame is located on the circle center axis of the primary treatment box, the bottom of the filtering frame is fixedly connected with the first rotating disc, and the top of the filtering frame penetrates out of the top plate. Compared with the prior art, through cooperation of the driving assembly and transmission, filtered wastewater is fed into different cavities for waiting, secondary pollution can be avoided, and the filtering efficiency is improved; the biological membrane filter cartridges are alternately fed into the biological treatment box, and the corresponding biological membrane filter cartridges are switched every time the chambers are switched, so that the situation that one biological membrane filter cartridge is used for a long time is avoided, the treatment efficiency is improved, the intermediate waiting time is shortened, and meanwhile, impurities accumulated in the primary treatment box are conveniently cleaned.
Owner:YANGXIN DINGZHI AGRI DEV CO LTD

Discrete carbon-based biological base material for targeted treatment of high-concentration organic wastewater and preparation process of discrete carbon-based biological base material

The invention relates to the field of adsorption materials, in particular to a discrete carbon-based biological base material for targeted treatment of high-concentration organic wastewater and a preparation process thereof.The discrete carbon-based biological base material is prepared from, by weight, 65-70 parts of activated carbon fibers, 8-10 parts of PLA fibers, 5-7 parts of sodium lignin sulfonate, 5-8 parts of ferroferric oxide magnetic particles and 8-10 parts of a carbon nitride catalyst; biPO4 is doped in the carbon nitride catalyst. According to the discrete carbon-based biological base material, the activated carbon fibers rapidly adsorb organic matters in high-concentration wastewater, the PLA releases a carbon source and accelerates formation of a biological membrane, and the biological membrane is degraded by taking the adsorbed organic matters as a substrate; the carbon nitride catalyst generates active oxygen under visible light to oxidize small molecular acid, and ferroferric oxide magnetic particles catalyze the reaction to break refractory toxins (such as antibiotics); after the reaction, the magnetic field recovers the material, sodium lignin sulfonate protects ferroferric oxide magnetic particles from corrosion, and regeneration performance is provided.
Owner:HUNAN ZHONGFU ENVIRONMENTAL PROTECTION TECH RES INST CO LTD

River ecological management system based on artificial intelligence

The invention relates to the technical field of river channel treatment, and discloses an artificial intelligence-based river channel ecological treatment system, which comprises: a water purification unit, which comprises a biological membrane box and an activated carbon box; the ecological restoration unit comprises a gridding protection slope and a drip irrigation pipe network; the buffer pool is arranged on one side of the river channel and communicates with the rainwater pipe network, and an electric flashboard is arranged between the buffer pool and the river channel; the solar power supply unit is integrated with the water purification tank and supplies energy to the system; and the intelligent control unit realizes self-adaptive control through a multi-parameter sensor and an Internet of Things module. Environmental data are collected in real time through the sensor group, a training machine learning model is used for predicting irrigation and flood drainage requirements, the system automatically switches working modes according to a prediction result, irrigation or flood drainage is carried out, the water purification unit can purify water, and through modular design, intelligent control and ecological restoration technologies, the system can be widely applied to the field of irrigation and flood drainage. The problems of irrigation, water quality deterioration and flood drainage are synchronously solved.
Owner:BENGBU COLLEGE

7-dehydrocholesterol liposome and application thereof

The invention relates to the technical field of biological medicine, in particular to 7-dehydrocholesterol liposome and application thereof. According to the invention, a biological membrane modified liposome is constructed, and the biological membrane modified liposome comprises an ROS responsive liposome, a neutrophile granulocyte membrane and a renal tubular epithelial cell membrane; the biofilm modified liposome has an active oxygen species (ROS) responsive release function and a dual targeting capability, has the advantages of an integrated drug effect carrier, ROS triggered release, dual bionic targeting, strong target cell uptake and multi-mechanism ferroptosis resistance, and can be used for preparing the biofilm modified liposome. The compound can be used for treating ferroptosis related diseases such as acute kidney injury, myocardial ischemia-reperfusion injury and cerebral ischemia-reperfusion injury, and has wide clinical popularization value.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Biological membrane car washing sewage circulating filter with external vibrator

The utility model discloses a biological membrane car washing sewage circulating filter with an external vibrator. The biological membrane car washing sewage circulating filter with the external vibrator comprises a pretreatment system, a biological membrane reactor, a vibrator device, a filtering system, a disinfection system and a water circulation system, the vibrator device is externally arranged, so that the occupied space in the bio-membrane reactor can be reduced, and the distribution of a flow field and a bio-membrane in the bio-membrane reactor cannot be directly influenced. The vibrator device is arranged outside, so that the vibrator device is more convenient to overhaul, maintain and replace, and the internal structure of the bio-membrane reactor does not need to be disassembled.
Owner:GUANGDONG TIANJIAO INTELLIGENT MFG ELEMENTS CONFIGURATION CO LTD +1

Small molecule compound for regulating and controlling catalytic activity of tetrahymena ribozyme as well as screening method and application of small molecule compound

The invention discloses a small molecule compound for regulating and controlling the catalytic activity of tetrahymena ribozyme and a screening method and application thereof, based on FRET (Fluorescence Resonance Energy Transfer) high-throughput entity screening, virtual screening, a biological membrane interference technology, a freezing electron microscope structure analysis technology and other technologies are combined to form a set of complete and efficient RNA (Ribonucleic Acid) targeted small molecule compound extraction method; the tetrahymena ribozyme is specifically subjected to small molecule compound screening; aiming at research and regulation of tetrahymena ribozyme; meanwhile, the invention aims to develop a high-throughput and systematic small-molecule compound screening method which is used for rapidly and efficiently screening potential small-molecule inhibitors so as to accelerate the discovery and research and development process of new drugs.
Owner:CHENGDU FUTURE MINGJING LIFE TECH CO LTD

Improved biological membrane method MABR sewage treatment device

The application belongs to the technical field of sewage treatment, and particularly relates to a modified biological membrane method MABR sewage treatment device, which comprises a MABR biological membrane, a sedimentation tank, a discharge port, a cleaning assembly and a power assembly, the MABR biological membrane is arranged in the sedimentation tank, the discharge port is arranged at the bottom end of the sedimentation tank, the cleaning assembly comprises a moving plate and a filter barrel, the moving plate is slidingly installed in the inside of the sedimentation tank, the outer wall of the moving plate is attached to the inner wall of the sedimentation tank, the filter barrel is provided with an opening, and the filter barrel is arranged on the opening; the filter barrel is driven to slide by the moving plate, so that the sediments can be pushed to one side of the sedimentation tank; the sliding of the cleaning assembly is controlled by the power assembly; the end of the moving plate, which is away from the filter barrel, is slidingly installed with a first baffle and a second baffle; the first baffle and the second baffle are controlled to slide relative to each other; and the above structure can effectively improve the efficiency of sewage treatment.
Owner:NANJING SHUIQINGYUAN ENVIRONMENTAL PROTECTION TECH CO LTD

Three-phase loop bioreactor

The utility model discloses a three-phase circulation bioreactor. The three-phase circulation bioreactor comprises a shell, a communicated exhaust pipe is fixedly connected to the center of the top of the shell; a communicated overflow pipe is fixedly connected to the side wall of the top of the shell; a blow-off pipe and a water inlet pipe which are communicated with each other are fixedly connected to the periphery of the bottom of the shell; a net plate is fixedly connected to the middle of the interior of the shell; a biofilm carrier filler is arranged at a position, corresponding to the upper part of the screen plate, in the shell; the gas escapes upwards, so that the gas returns to the upper part of the water body after reaching the bottom of the sewage, the circulation effect is achieved, and the mixing effect of the gas and the sewage is further improved; besides, the spray heads can rotate along with the hollow shaft, and the spray heads on the different vortex-shaped pipes are arranged in a staggered manner, so that the distribution density of the gas in the sewage water body can be improved, the mixing effect between the sewage and the gas is further improved, the biological treatment reaction speed of the sewage is prevented from being influenced, and the purification efficiency of the reactor is improved.
Owner:HEFEI CITY KEPOSHINE ENVIRONMENTAL PROTECTION & TECH CO LTD

Local magnetothermal coupling biological rotating disc enhanced cold region sewage treatment method and system

The invention relates to a local magnetothermal coupling biological rotating disc enhanced cold region sewage treatment method and system. The system comprises a reactor, a biological rotating disc for growing a biological membrane, a magnetic heat carrier, an alternating magnetic field generator and a motor for driving the biological rotating disc to rotate, the reactor comprises an air exposure area and a sewage area from top to bottom, a water inlet is formed in the lower part of the left side wall of the reactor, a water outlet flush with the water level of the sewage area is formed in the upper part of the right side wall, the reactor is further provided with vent holes, and the air exposure area is communicated with air through the vent holes; the biological rotating disc is partially immersed in the sewage area and partially exposed to the air exposure area in the radial direction; the air exposure area is located in the magnetic field action range of the alternating magnetic field generator, the magnetic heat carrier is arranged on at least one side of the biological rotating disc, and the magnetic heat carrier generates a magnetocaloric effect under the action of the magnetic field so as to increase the temperature of the biological membrane. According to the invention, the synergistic effect of precise heating of the biological membrane and the metabolic process of the biological membrane is realized, and the efficient and energy-saving sewage denitrification process at low temperature is realized.
Owner:HARBIN INST OF TECH

Thermal insulation structure of biological membrane filter

The utility model relates to a heat preservation structure of a biological membrane filter tank, which comprises a tank body, a heat preservation framework matched with a tank opening in shape is fixedly arranged above the water surface of the tank body, a heat preservation film is covered above the heat preservation framework, and an air area for air circulation is formed between the heat preservation framework and the water surface. By adopting the scheme, the utility model provides the heat preservation structure of the biological membrane filter tank, which is stable in effluent quality.
Owner:WENZHOU CANGNAN PUBLIC UTILITY DEV CO LTD

Preparation method of antibacterial enhanced ABS (Acrylonitrile Butadiene Styrene) plastic

InactiveCN120383807APolymer scienceMeth-
The invention discloses a preparation method of antibacterial enhanced ABS (acrylonitrile-butadiene-styrene) plastic, and relates to the field of ABS plastic. A hyperbranched polylactic acid network and an ABS matrix form an interpenetrating structure, and molecular chain slippage is jointly inhibited by a cross-linking point of trimethylolpropane triacrylate and a physical enhancement effect of nano SiO2, so that the tensile strength and the impact strength of the material are improved; bacterial cell membranes are destroyed through a quaternary ammonium salt group with positive electricity, synthesis of fungal cell walls is interfered and formation of biological membranes is inhibited through boric acid molecules, hypha colonization is physically hindered through high crosslinking density of a hyperbranched PLA network, and therefore the bacteriostasis rate on bacteria and fungi is increased.
Owner:NINGBO JINCHENG NEW MATERIALS CO LTD

Antibacterial peptide Mp-gc21, precursors and uses thereof

The application belongs to the technical field of antibacterial peptides, and particularly relates to an antibacterial peptide Mp-GC21, a precursor thereof and application. The amino acid sequence of the antibacterial peptide Mp-GC21 is shown as SEQ ID NO:1, wherein the C terminal is subjected to amidation modification, and two cysteines are connected through a disulfide bond; and the amino acid sequence of the precursor is shown as SEQ ID NO:3. The antibacterial peptide Mp-GC21 is separated from the flower frog, has broad-spectrum antibacterial activity, and has good bacteriostatic and bactericidal effects on standard strains and clinically derived drug-resistant strains of Acinetobacter baumannii, Escherichia coli and Staphylococcus aureus, and can target to destroy the cell membrane of bacteria, remove the biofilm and inhibit the formation of the biofilm. Moreover, the antibacterial peptide Mp-GC21 has good stability, does not have hemolytic activity, cytotoxicity and in-vivo toxicity, and is not easy to induce drug resistance of strains.
Owner:GUANGDONG LABORATORY OF SOUTHERN OCEAN SCIENCE AND ENGINEERING (GUANGZHOU)