134 results about "Biological structure" patented technology

Systems and methods for automatically populating a post-operative report of a surgical procedure are disclosed. A system may include at least one processor configured to implement a method including receiving an identifier of a patient, an identifier of a healthcare provider, and surgical footage of a surgical procedure performed on the patient. The method may include analyzing frames of the surgical footage to identify phases of the surgical procedure based on interactions between medical instruments and biological structures and, based on the interactions, associate a name with each phase. The method may include determining a beginning of each phase and associating a time marker with the beginning of each phase. The method may include populating a post-operative report with the patient identifier, the names of the phases, and time markers associated with the phases in a manner that enables the health care provider to alter the post-operative report.

In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

The invention discloses a molecular resolution microscopy (MITI) (Molecular-level Imaging Based on Twoo-color Imaging) based on two-color single molecule positioning, and relates to the technical field of microscopy, in particular to the MITI (Molecular-level Imaging Based on Twoo-color Imaging) based on two-color single molecule positioning. According to the invention, by using a two-color imaging method, the positioning points of the fluorescent molecules which cannot be distinguished originally successfully pass through a two-color method, different positioning point sets are distributed to corresponding fluorescent channels for successful distinguishing, and then the positioning points of the fluorescent molecules are obtained by fitting the distribution of the positioning points of the fluorescent molecules again. And the center position of the fluorescent molecule positioning point distribution and the positioning precision improved again are obtained, so that the resolution is improved. According to the method, the spatial resolution of 2nm can be achieved at most, and an important means is provided for analysis of a molecular-scale biological structure and an interaction process.

The utility model discloses a gas dynamic pressure radial bearing based on a tenon biological structure, and relates to the technical field of radial dynamic pressure gas bearings. Comprising a bearing rotor and a bearing sleeve, grooves are formed in the peripheral surface of the bearing rotor, the grooves are distributed in the cylindrical spiral line direction, the grooves are distributed in the circumferential direction of the bearing rotor at intervals to form a groove set, a zone area is formed between any two adjacent grooves, the section of the zone area is in a streamline shape, and the bearing rotor is arranged in the bearing sleeve. And in a non-working state, the table area is in contact with the inner wall of the bearing sleeve, and in a working state, gas outside the bearing can flow into the bearing sleeve from the gap, and a gas film with high internal pressure is formed in the middle of the bearing sleeve. According to the aerodynamic radial bearing based on the tenon biological structure, the bearing capacity of the bearing is enhanced, the stability of the bearing is improved, the friction loss in the bearing is reduced, the service life of the bearing is prolonged, and the stability of the bearing is improved.

The invention discloses a magnetic control system for sensing mechanical characteristics of an organoid, and relates to the field of organoid operation. The invention aims to solve the problems that an existing microscopic biological structure mechanical characteristic measuring system is insufficient in working space, small in applied force, low in precision, poor in flexibility and difficult to meet the requirement for mechanical characteristic measurement of organoids in biomedical research. An execution module is of an octupole magnetic tweezers structure and is used for executing mechanical actions of a magnetic control system on the similar organs; the visual feedback module is used for tracking and positioning the magnetic beads in the execution module through a microscope camera; the electric control module is used for supplying power to eight magnetic poles of the eight-pole magnetic tweezers structure; and the controller is used for controlling the expected control current of the electric control module according to a driving target.

The invention discloses a bamboo-like structure annularly-reinforced bamboo composite pipe and a preparation method thereof.The bamboo composite pipe sequentially comprises a lining layer, a reinforcing layer, an annular reinforcing layer and an outer protective layer from inside to outside, the thickness of the inner reinforcing layer, the thickness of the middle reinforcing layer and the thickness of the outer reinforcing layer are sequentially reduced, and radial impact resistance of the bamboo composite pipe is reinforced; according to the bamboo composite pipeline, the natural structure of'sparse inside and dense outside 'and'bending without bending' of the bamboo vascular bundle is reproduced, the circumferential stress of the pipeline can be effectively and gradually transmitted to the outer layer from the inner layer of the pipeline wall in the circumferential bearing process, local cracking caused by stress concentration is avoided, and the circumferential impact resistance and bending resistance of the bamboo composite pipeline can be remarkably improved. The circumferential reinforcing layer imitates the natural structure of bamboo wood, the biological structure characteristic that bamboo joints are periodically distributed in the length direction of bamboo stalks is reproduced, the radial ring stiffness and the deformation resistance of the bamboo composite pipe can be remarkably improved, and the defect that the transverse strength of the bamboo composite pipe is insufficient is overcome.

A device for providing a magnetic treatment by evoking muscle contraction by a time-varying magnetic field and providing a RF treatment by heating biological structure. The device may provide a pressure treatment. The device includes an applicator having an RF electrode and a magnetic field generating device. The device may also include a main unit, a human machine interface, and a control unit. The control unit adjusts a signal provided to the RF electrode and creates an RF circuit, and also adjusts the signal provided to the magnetic field generating device and creates a magnetic circuit electrically insulated from the RF circuit. The RF circuit may include a power source and a power amplifier, and the magnetic circuit may include an energy storage to supply the magnetic field generating device with electric current.

A patch to be placed over an injury or defect in tissue in a biological structure having a lumen and preventing migration of contents of the biological structure through the injury or the defect. The patch includes an adhesive layer configured to adhere to the biological tissue via formation of hydrogen or covalent bonds with chemical groups present in the biological tissue and a backing layer coupled to and coextensive with the adhesive layer, the backing layer configured to be impervious to the contents.

The invention provides a process for preparing a three-dimensional graphene foam metal composite material by a biological template method. The preparation method comprises the following steps: preparing through an innovative biological template method process, carrying out carbonization-activation treatment on a natural hierarchical porous biological structure serving as a sacrificial template to form a three-dimensional graphene foam skeleton with bionic hierarchical pore channels, and carrying out in-situ compounding of copper / silver metal nanoparticles through a pulse electrodeposition technology to obtain the composite material. And finally, the three-dimensional graphene foam metal composite material with ultrahigh thermal conductivity and eco-friendly characteristics is constructed. The core breakthrough of the heat-conducting property is as follows: a bionic heat transfer framework is optimized, graded pores derived from a biological template form a phonon efficient transfer path, and the axial heat conductivity is improved by more than 40% compared with that of a material prepared by a traditional chemical foaming method; according to graphene-metal interface cooperation, metal nanoparticles directionally grow on the edge of a graphene sheet layer and hole wall defect sites, and interface thermal resistance is reduced to 8.7 * 10 <-9 > m < 2 > K / W by forming a coherent interface; cross-scale heat flow guide control is achieved, specifically, phonon conduction with the in-plane heat conductivity being 1600 W / (m.K) is achieved through a high-crystallinity graphene domain in a micropore, and an electron conduction heat diffusion network is constructed through a metal filling layer in a macropore channel.

The invention relates to an early strength concrete material for an expansion joint anchoring area and a preparation method thereof, and relates to the technical field of building materials, the early strength concrete material for the expansion joint anchoring area comprises the following components in parts by mass: gel master batch, coarse aggregate, fine aggregate, silica fume, mineral powder and a polycarboxylic acid water reducer; the gelling master batch is prepared from the following components in parts by mass: tricalcium silicate, anhydrous calcium sulphoaluminate, polyvinyl alcohol, polypropylene fiber and water; the preparation method comprises the steps of gelling master batch preparation, shearing and flaking, and mixing and forming. According to the early-strength concrete material for the expansion joint anchoring area and the preparation method of the early-strength concrete material, the concrete in the anchoring area is modified by using an organic matter as a crystal nucleus, so that a compact and ordered organic-inorganic cross-linked structure with a biomimetic structure is formed, and the early-strength performance and tensile toughness of the concrete are remarkably improved.

An active and passive coupling bionic stubble cutting device based on jaw curves of African beetles relates to the technical field of agricultural machinery, and comprises a power transmission and frame component playing a role in integral supporting and transmission, a plurality of active stubble cutting components and a plurality of passive stubble fixing components are mounted on the power transmission and frame component, and the active stubble cutting components and the passive stubble fixing components are mounted on the power transmission and frame component. The passive stubble fixing component is rotatably mounted at the front end of the power transmission and rack component and passively and positively rotates along the advancing direction of a machine tool, and the active stubble cutting component is mounted at the rear end of the power transmission and rack component and is driven by the power transmission and rack component to reversely rotate; and a composite working area is formed between the active stubble cutting component and the passive stubble fixing component. According to the bionic stubble cutting device, by integrating the advantages of a biological structure, the purposes of greatly improving the stubble cutting operation quality, reducing power consumption and providing technical support for popularization and application of a follow-up sowing operation agricultural technology are achieved.

The invention relates to the technical field of image data processing, in particular to an image segmentation method and system applied to marine plankton. The method comprises the following steps: acquiring an in-situ microscopic image of marine plankton, carrying out binarization processing and connected domain analysis on the in-situ microscopic image, and screening out a biological adhesion block mass to be processed; synchronously extracting the edge contour of the biological adhesion block mass to be processed, and calculating a biological structure integrity score; selecting the candidate segmentation path with the highest biological structure integrity score as an optimal segmentation line; curvature smooth completion is carried out along the optimal segmentation line, and a single biological image is obtained; and inputting the single biological image into a pre-trained classifier to obtain a biological abundance data set. According to the method, high-precision automatic identification and abundance statistics of plankton in a complex marine environment are realized by screening and positioning the adhesion block mass, carrying out adaptive adhesion segmentation and combining multi-dimensional morphological feature classification.

The invention discloses a biological organ structure in-vitro preparation instrument, which is a precise device for preparing a biological organ structure model for in-vitro culture, relates to the technical field of biomedical experiment research, and comprises a slicing part, a micro-motion part and a linkage part, the micro semi-automatic device creatively combines the biological structure characteristics of a microelectronic control system, peripheral nervous nerves, central nervous nerves, various solid visceral organs and tumor tissues, and adopts a spiral micrometer micrometer order stepping device as an organ-like tissue thickness control structure. And the organoid tissue structure with the thickness of 100-500 microns can be intuitively, conveniently and efficiently prepared under the in-vitro sterile condition.

There is provided a bioimaging system for determining a spatial distribution of one or more physical properties within a biological structure, the system comprising: a data input configured to receive a plurality of measurements related to one or more physical fields; and a processing device configured to determine a spatial distribution of one or more physical properties within the biological structure using the plurality of measurements. The processing device forms a discretized full order model of the biological structure, describes a baseline spatial distribution of the biological structure using the model, and determines optimized values of coefficients describing the baseline spatial distribution based on the plurality of measurements. The processing device also forms a hybrid model comprising baseline spatial distribution coefficients and a set of deviation full-order model coefficients describing deviations relative to the baseline spatial distribution, determines optimized values for the baseline spatial distribution coefficients and the deviation full-order model coefficients of the hybrid model, and determining a spatial distribution of one or more physical properties within the biological structure using the optimized values of the coefficients.

The present disclosure provides a method for bioprinting a 3D structure comprising one or more bio-related materials on a superhydrophobic surface. In one embodiment, the method includes providing a composition having one or more bio-related materials dispersed in a biocompatible medium. A pattern comprising a hydrophilic material is deposited on a defined region of the superhydrophobic surface, the pattern being modeled after a biological structure. A composition having one or more bio-related materials is then bioprinted onto the hydrophilic surface to form a 3D structure, the hydrophilic surface maintaining the 3D structure in a desired position or shape on the superhydrophobic surface.

A biological imaging system for determining a spatial distribution of one or more physical properties within a biological structure is provided, comprising a data input arranged to receive a plurality of measurements relating to one or more physical fields and a processing device arranged to determine a spatial distribution of one or more physical properties within the biological structure using said plurality of measurements. The processing device forms a discretized full order model of the biological structure, uses this model to describe a baseline spatial distribution of the biological structure and determines optimised values for the coefficients describing the baseline spatial distribution based on the plurality of measurements. The processing device also forms a hybrid model comprising the baseline spatial distribution coefficients and a set of deviation full order model coefficients which describe a deviation from the baseline spatial distribution, determines optimised values for the baseline spatial distribution coefficients and the deviation full order model coefficients of the hybrid model and determines the spatial distribution of one or more physical properties within the biological structure using optimised values of the coefficients.

Methods and systems for characterizing a biological structure including: obtaining image data for the biological structure using an imaging system; constructing a volumetric dataset of the biological structure based on the image data; determining at least one of a plurality of sections along a plane or curve within the volumetric dataset; and characterizing, using a trained algorithm and based on at least one of the plurality of sections, the biological structure for potential tissue type or disease state.

To solve the problem in which a view of a biological structure provided by an imager is limited when an imaging environment is cloudy or turbid.SOLUTION: An endoscopic system includes: an endoscopic imager configured to capture images of a target site within a living body; and a processor configured to determine one or more image metrics for each multiple image frames captured over a time span, analyze changes in the image metrics over the time span, and determine a turbidity metric for the target site based on the analyzed changes in the image metrics.SELECTED DRAWING: Figure 5

Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

This invention discloses a microscale biomimetic toughening additive manufacturing method for shell-like features. To address the current difficulty in achieving a balance between strength and toughness in laser additive manufacturing of metal components for the aerospace field, this invention draws inspiration from the "brick-and-mortar" biological structure of the nacreous layer of a shell. It employs a method of continuous laser layer-by-layer melting and forming / ultrafast laser interlayer micro-region precise toughening to design and construct a biomimetic toughening material with spatial overlap of "soft" and "hard" regions, thereby achieving a synergistic improvement in the strength and toughness of laser additive manufacturing of metal components.

A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. Methods of biological tissue modification are also provided. The systems and methods disclosed here are uniquely different in that they aim to target, plan and treat target tissue, and selectively destroy and modify cellular architecture, but with specific intent and treatment parameters specialized for retaining specific target physical biological structures within the cell itself.

A major obstacle in the field of biotherapeutics is the need for platform technologies that enable high bioavailability and long-term therapeutic exposure of biotherapies in localized disease. Traditional approaches result in problematic trade-offs, such as toxicity and off-target side effects. The present disclosure provides compounds comprising follistatin domain 1 (FSD1) of follistatin (FST), which can bind to biological structures, such as the extracellular matrix, via heparan sulfate without the undesired neutralizing effects on the activity of activin A, myostatin, and GDF11, as full-length follistatin does. The present invention relates to fusion or conjugated proteins, compositions thereof, constructs or vectors encoding them, their medical uses, and methods for biotherapeutics.

The invention belongs to the technical field of gene recombination, and particularly relates to a recombinant human III-type triple helix collagen, a recombinant yeast strain for expressing the recombinant human III-type triple helix collagen and a construction method of the recombinant human III-type triple helix collagen. The amino acid sequence of the recombinant human III-type triple-helix collagen is shown as SEQ ID NO. 1, and the recombinant human III-type triple-helix collagen has triple-helix conformation close to a natural biological structure of collagen and has good application value and potential. According to the recombinant yeast strain disclosed by the invention, human-derived III-type collagen and proline hydroxylase are co-expressed in yeast cells without YPS1 protease, and meanwhile, a gene beneficial to vesicle transport and protein folding is transferred, so that hydroxylation of the recombinant collagen can be realized, a natural triple helix conformation is formed, and the recombinant yeast strain can be used for preparing a recombinant collagen product. The degradation problem of the collagen in the expression process can be solved, and the extracellular secretion expression of the triple helix collagen is realized.

The invention belongs to the technical field of gas sensing, and discloses a preparation method of an indium oxide gas-sensitive material based on a bamboo biological template, which comprises the following steps: taking natural bamboo as a biological structure template, introducing an indium source precursor into a template pore channel by a solution impregnation method, drying, and carrying out high-temperature calcination in an air atmosphere. According to the heat treatment process, thermal degradation and removal of the biological template are achieved, decomposition and oxidation of the precursor are synchronously induced, and finally the indium oxide material with the bamboo biological form and the high specific surface area is generated. The obtained material shows high response and recovery speed to nitrogen dioxide gas, the response value exceeds three thousand, meanwhile, precious metal and a traditional chemical preparation method do not need to be used in the preparation process, and the green chemical concept of saving energy and reducing pollution is achieved.

A patch to be placed over an injury or defect in tissue in a biological structure having a lumen and preventing migration of contents of the biological structure through the injury or the defect. The patch includes an adhesive layer configured to adhere to the biological tissue via formation of hydrogen or covalent bonds with chemical groups present in the biological tissue and a backing layer coupled to and coextensive with the adhesive layer, the backing layer configured to be impervious to the contents.

A biological structure identification system includes an optical imaging system configured to illuminate a liquid biopsy sample for a subject. The liquid biopsy sample has one or more biological structures that are labeled with one or more fluorophores associated with a fluorescence assay for a cancer allowing detection of emitted electromagnetic radiation from the liquid biopsy sample as image data. The system also includes a processing system configured to identify a cancer stage for the subject by determining a predetermined cancer stage profile from a set of predetermined cancer stage profiles to which the subject profile is most similar.

A device for providing a magnetic treatment by evoking muscle contraction by a time-varying magnetic field and providing a RF treatment by heating biological structure. The device includes an applicator having an RF electrode and a magnetic field generating device. The device may also include a main unit, a human machine interface, and a control unit. The control unit adjusts a signal provided to the RF electrode and creates an RF circuit, and also adjusts the signal provided to the magnetic field generating device and creates a magnetic circuit electrically insulated from the RF circuit. The RF circuit may include a power source and a power amplifier, and the magnetic circuit may include an energy storage to supply the magnetic field generating device with electric current.

The invention discloses a structure-enhanced starch-based aerogel capable of improving porosity as well as a preparation method and application thereof, the aerogel comprises enzyme modified starch and natural starch, and the enzyme modified starch is obtained by improving the natural starch by adopting a compound enzyme system composed of multiple amylases. The method comprises the following steps: S1, modifying natural starch through a compound enzyme system to obtain enzyme modified starch; s2, mixing the enzyme modified starch with natural starch in proportion, adding water to form a composite suspension, and performing gelatinization treatment to obtain a gelatinized starch system; and S3, carrying out gelation, freezing and drying treatment on the gelatinized starch system to obtain the aerogel. The aerogel can be applied to thermal insulation materials, adsorption materials, bio-based structural materials or functional porous materials. The molecular structure of the starch is controllably adjusted through the synergistic effect of different enzyme systems, so that the porosity, the structural uniformity and the mechanical stability of the aerogel are remarkably improved on the premise of not introducing a chemical cross-linking agent.