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140 results about "Reconstructive surgery" patented technology
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Reconstructive surgery is, in its broadest sense, synonymous with plastic surgery. Commonly, however, reconstructive surgery is understood as the use of surgery to restore the form and function of the body, which does not include aesthetic or cosmetic surgery. For example, plastic surgeons, maxillo-facial surgeons and otolaryngologists do reconstructive surgery on faces after trauma and to reconstruct the head and neck after cancer.
Method of facial reconstructive surgery using a self-anchoring tissue lifting device
ActiveUS8721666B2Good cosmetic effectSimplify facial reconstructive surgeriesSuture equipmentsCosmetic implantsEyelidCheek
Owner:ETHICON INC
Systems and methods for intra-operative stimulation
ActiveUS20070191915A1Accurate assessmentAccurate selective stimulationElectrotherapySurgical instrument detailsMuscle contractionRange of motion
Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and / or identify nerve damage occurring prior to surgery and / or verify range of motion or attributes of muscle contraction during reconstructive surgery. A stimulation control device may incorporate a range of low and high intensity stimulation to provide a stimulation and evaluation of both nerves and muscles. A stimulation control device is removably coupled to a surgical device or is imbedded within the medical device to provide a stimulation and treatment medical device. A disposable hand held stimulation system includes an operative element extending from the housing, the housing includes an operative element adjustment portion and a visual indication to provide feedback or status to the user.
Owner:CHECKPOINT SURGICAL
Methods, devices, and manufacture of the devices for musculoskeletal reconstructive surgery
ActiveUS20170014169A1Guaranteed functionAccurate analysisBone implantJoint implantsBite force quotientCombined use
A device used in conjunction with fixation hardware to provide a two-stage process to address the competing needs of immobilization and re-establishment of normal stress-strain trajectories in grafted bone. A method of determining a patient-specific stress / strain pattern that utilizes a model based on 3D CT data of the relevant structures and cross-sectional data of the three major chewing muscles. The forces on each of the chewing muscles are determined based on the model using predetermined bite forces such that a stiffness of cortical bone in the patient's mandible is determined. Based on the stiffness data, suitable implantation hardware can be designed for the patient by adjusting external topological and internal porous geometries that reduce the stiffness of biocompatible metals to thereby restore normal bite forces of the patient.
Owner:OHIO STATE INNOVATION FOUND +1
Thermally reversible implant and filler
The invention relates to the use of a thermal reversible gel, such as a copolymer composition, as a biological filler or implant. The gel has a semi-solid form at body temperature, but upon cooling to a temperature below a threshold level, the gel is liquefied and can be re-shaped, re-sized, manipulated or removed from the body. The gel may be used as a subcutaneous implant, a biological filler, joint or tissue spacer, for wrinkle filling or other cosmetic implants, as a soft-tissue replacement for reconstructive surgery, or as a barrier within the lumen of a biological structure, such as a blood vessel. The implant may be used to provide reversible birth control by providing, for example, a reversible barrier to the cervix or a reversible blockage of the lumen of the vas deferens.
Owner:CHENG YU LING +3
Systems and methods for intra-operative stimulation
ActiveUS7878981B2Accurate selective stimulationAssess the quality of surgical interventionsElectrotherapySurgical instrument detailsMuscle contractionEngineering
Owner:CHECKPOINT SURGICAL
Method for repair and reconstruction of ruptured ligaments or tendons and for treatment of ligament and tendon injuries
A method and a means for repair and reconstruction of ruptured ligaments and tendons by in vivo or ex vivo repair and reconstruction surgical procedures. The method comprises providing a biodegradable sleeve placed around the frayed edges of an injured ligament or tendon for protecting the ligament or tendon injury with a protective shield. A composition comprising a biodegradable tissue adhesive applied on top of, around and / or between the frayed edges of the injured ligament.
Owner:HISTOGENICS
Systems and methods for intra-operative stimulation
Owner:CHECKPOINT SURGICAL
Biological and adsorbable bone internal fixation implantation instrument
InactiveCN101283922APromote healingUniform corrosion degradationInternal osteosythesisProsthesisInternal bone fixationReconstructive surgery
The invention relates to a bone implanting and internal fixation appliance with bioactivity and absorbability, which belongs to the field of bio-medical appliances, particularly to the field of medical appliances used for bone wound surgery, reparative and reconstructive surgery and plastic and cosmetic surgery. The appliance includes bone nails and a bone plate made of magnesium and the alloy thereof with bioactivity and absorbability. The bone implanting and internal fixation appliance is a bone internal fixation device, which comprises a blade plate and matched screws, intramedullary nails, a fracture and dislocation fixing device of vertebral column, bone nails or screws having individual fixation effect, wherein the bone internal fixation device is made of magnesium and the alloy thereof with bioactivity and absorbability. The bone internal fixation device can solve the problem in bioactivity of prior bone internal fixation device and promote healing the tissue where the device in implanted. The device also includes a protection layer prepared on the surface of the internal fixation device for controlling the degradation rate of magnesium alloy and the dissolution rate of magnesium ions, thus controlling the bioactivity and the absorption speed of the magnesium alloy device in an organism.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI
Self-anchoring tissue lifting device, method of manufacturing same and method of facial reconstructive surgery using same
ActiveUS20090082791A1Good cosmetic effectSimplify facial reconstructive surgeriesSuture equipmentsCosmetic implantsReconstructive surgeryCheek
A self-anchoring tissue lifting device for use with facial cosmetic reconstructive surgery includes an implant and a removable foil cover disposed on the implant. The implant includes an elongated mesh strip having a distal end on which is situated a tissue anchoring fleece material. Opposite lateral edges of the mesh material are preferably laser cut during the manufacturing process of the implant to provide a plurality of tissue engaging prickles along the longitudinal length of the implant. For treating the mid face and jowl, a stab incision is made within the hairline of the temple region of the patient and the device is applied from the temporal area to the peak of the ipsilateral cheek to capture the malar fat pad to correct midface abnormalities or the ptotic tissue causing the jowl.
Owner:ETHICON INC
System and Method for Multi-Color Laser Imaging and Ablation of Cancer Cells Using Fluorescence
ActiveUS20140187967A1Reduce deficiencyDiagnostics using fluorescence emissionSurgical instrument detailsCancer cellWound care
A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.
Owner:ACCUVEIN
Nipple/Areola Protective Cover
A protective cover for nipples and areolas employable during nipple or breast reconstructive surgery. The device has an axial cavity in a central portion of a resilient body employable for placement about the nipple or reconstructed nipple therein. The device is infinitely customizable in axial cavity diameter and vertical height by means of one or a plurality of removably engaged central portions.
Owner:POLLACK LARRY H
Virtual cosmetic and reconstructive surgery systems, methods, and apparatuses
ActiveUS7587075B1Accurate predictionUltrasonic/sonic/infrasonic diagnosticsMechanical/radiation/invasive therapiesBreast implantBreast augmentation
A method for producing a virtual forecasted model of a breast augmentation subject, comprising, receiving a preoperative subject's scanned image, wherein the scanned image comprises a three dimensional image, converting the scanned image from a scanned image format to a VRML image format, importing the converted VRML image into a VRML image editor, receiving, from a breast implant database, at least one modeled virtual breast implant, wherein the received virtual breast implant is selected based on a desired actual breast implant that is to be implanted in the preoperative subject, and embedding the received virtual breast implant in the preoperative subject's converted VRML image.
Owner:NOVAPTUS SYST
Systems and methods for intra-operative stimulation within a surgical field
InactiveUS20110060242A1Accurate assessmentElectrotherapySurgical needlesMuscle contractionRange of motion
Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and / or identify nerve damage occurring prior to surgery and / or verify range of motion or attributes of muscle contraction during reconstructive surgery. Such improved assemblies may be utilized in embodiments of methods according to the present invention allowing, preferably by a single hand, manipulation, carrying, parameter adjustment and / or informational feedback generation from within a surgical field. Single-handed operation and easily identifiable feedback generation is desirable especially where focused attention is required, such as during surgery observed through a microscope.
Owner:CHECKPOINT SURGICAL
System and method for site specific therapy
InactiveUS7717871B2Optimize allocationLower the volumeDialysis systemsMedical devicesEngineeringPhysical therapy
A system, including catheter apparatus, and related method for performing site specific therapy. The catheter apparatus can include one or more semipermeable microcatheters for use in performing site specific microdialysis. The system and method are particularly suited for use in addressing cerebral edema by affecting the osmolar relationship between fluids making up the brain tissue. Also disclosed is an apparatus having a delivery / recovery mechanism in the form of a pump reservoir and one or more catheters in the form of semipermeable microcatheters, for use in delivering and / or recovering fluid to and / or from a tissue site or for performing tissue engineering outside of the body. The apparatus can be used in a method to perform site specific microtherapy, including for the treatment of avascular necrosis, compartment syndrome, cerebral edema, and to improve skin flap survival in the course of reconstructive surgery.
Owner:TWIN STAR MEDICAL
Method and composition for repair and reconstruction of intervertebral discs and other reconstructive surgery
InactiveUS20070179620A1Highly effectiveReduce deliveryBone implantPharmaceutical delivery mechanismBiological bodyDisease
By providing an elastic form stable material which is capable of being delivered directly to a specific desired location within a living creature and providing increased strength and rigidity to the injected location, disorders of the intervertebral disc of a living creature are able to be effectively treated. Treatment of defects or voids in soft tissue is achieved with a variation of the subject material specific to each application. In the preferred method, the elastic form stable material is injected directly into the affected area, thereby achieving the desired result.
Owner:BONWRX INC
Systems and methods for intra-operative stimulation
ActiveUS20060200207A1Accurate assessmentElectrotherapyDiagnostic recording/measuringMuscle contractionRange of motion
Improved assemblies, systems, and methods provide safeguarding against nerve injury during surgical procedures and / or identify nerve damage occurring prior to surgery and / or verify range of motion or attributes of muscle contraction during reconstructive surgery. A stimulation control device may incorporate a range of low and high intensity stimulation to provide a stimulation and evaluation of both nerves and muscles. A stimulation control device is removably coupled to a surgical device or is imbedded within the medical device to provide a stimulation and treatment medical device.
Owner:CHECKPOINT SURGICAL
System and Method for Laser Imaging and Ablation of Cancer Cells Using Fluorescence
ActiveUS20140187879A1Reduce deficiencySurgical instrument detailsDiagnostics using fluorescence emissionCancer cellWound care
A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.
Owner:ACCUVEIN
Tissue Engineered Cartilage, Method of Making Same, Therapeutic and Cosmetic Surgical Applications Using Same
InactiveUS20100061962A1Uniform diameterDiameter is limitedBiocideCosmeticsReconstructive surgeryBioreactor
Cartilage has been constructed using biodegradable electrospun polymeric scaffolds seeded with chondrocytes or adult mesenchymal stem cells. More particularly engineered cartilage has been prepared where the cartilage has a biodegradable and biocompatible nanofibrous polymer support prepared by electrospinning and a plurality of chondocytes or mesenchymal stem cells dispersed in the pores of the support. The tissue engineered cartilages of the invention possess compressive strength properties similar to natural cartilage. Methods of preparing engineered tissues, including tissue engineered cartilages, are provided in which an electrospun nanofibrous polymer support is provided, the support is treated with a cell solution and the polymer-cell mixture cultured in a rotating bioreactor to generate the cartilage. The invention provides for the use of the tissue engineered cartilages in the treatment of cartilage degenerative diseases, reconstructive surgery, and cosmetic surgery.
Owner:US DEPT OF HEALTH & HUMAN SERVICES
Polymorphs of an androgen receptor modulator
InactiveUS20070129548A1Maintain good propertiesEasy to processOrganic active ingredientsSkeletal disorderDiseaseAging skins
Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.
Owner:MERCK SHARP & DOHME CORP
Virtual cosmetic and reconstructive systems, methods, and apparatuses
InactiveUS7424139B1Accurate predictionUltrasonic/sonic/infrasonic diagnosticsMedical simulationComputer graphics (images)VRML
The virtual surgery systems, methods, and apparatuses that provide for the prediction, evaluation, and validation of various cosmetic and reconstructive surgical procedures. The virtual surgery systems, methods, and apparatuses utilize a scanner, measurement software, queries to a postoperative patient scan catalog, conversion of a preoperative image to a Virtual Reality Modeling Language (VRML) image, grafting and scaling of chosen postoperative surgery candidates, conversion from the converted VRML image to a scanner readable format, and measuring the forecasted VRML image.
Owner:NOVAPTUS SYST
17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators
Owner:MERCK SHARP & DOHME CORP
Thermogelling polymer blends for biomaterial applications
Thermogelling polymers are described containing poly (n-isopropyl acrylamide). Solutions of this polymer, copolymers or mixtures of the polymer with a second polymer such as poly(ethylene glycol), poly (vinyl pyrrolidone) or poly(vinyl alcohol) are liquids at room temperature and solids at body temperature. Thus, also provided are methods of implanting a hydrogel into a mammal by injecting the solution as a liquid at a temperature below body temperature into a selected site in the mammal at a temperature below body temperature, which then undergoes thermal phase transition to form a solid hydrogel in situ in the body as the implant warms to body temperature. Methods for using these thermal gelling materials in various applications including nucleus pulposus replacement / augmentation, wound care, disk replacement, cartilage replacement, joint replacement, surgical barriers, gastrointestinal devices, cosmetic and reconstructive surgery, and breast enlargement are also provided.
Owner:SYNTHES USA +1
Hybrid tissues for tissue engineering
InactiveUS20050002982A1Fast shapingFast modelingBiocideGenetic material ingredientsMixed Cellular PopulationReconstructive surgery
The present invention comprises an implantable device that provides artificial tissues for repair, augmentation and reconstructive surgery which have mechanical properties comparable to the natural tissues that they supplement or replace. Such devices can be produced by a tissue engineering method comprising seeding a polymer matrix with a first cell type and a second cell type and culturing the seeded matrix under conditions suitable for cell growth or maintenance, whereby a tissue comprising a mixed cell population containing both the first and second cell types is produced. The tissue produced by this method contains a mixed population in which the two cell types are intimately associated without apparent stratification and has mechanical properties which are intermediate between similarly produced tissues containing either one of the two cell types. This invention is particularly useful in forming implantable structural members.
Owner:MOONEY DAVID J +5
Low-swelling biocompatible hydrogels
Some aspects of the present disclosure relate to methods for treating a tissue by forming a low-swelling biodegradable hydrogel in situ adherent to the tissue. In embodiments the hydrogel exhibits negative swelling, i.e., shrinking. Such treatments may be utilized to in cosmetic or reconstructive surgery, in sphincter augmentation, treating nerve inflammation, and the like.
Owner:CONFLUENT SURGICAL
Monolithic in-situ cross-linked alginate implants
InactiveUS20110097367A1Increase volumeOrganic active ingredientsCosmetic preparationsLipoatrophyDisease
A method of making and using a monolithic alginate implant is described. The implant is formed by providing an uncrosslinked, highly pure and high molecular weight alginate solution and injecting the alginate solution into a patient at a predetermined site to form a gel body comprising the monolithic alginate implant. Spontaneous crosslinking of the monolithic alginate implant occurs at the predetermined site without the addition of an exogenous crosslinker. The implant may be used for treating medical conditions requiring support of sphincter musculature, reconstructive surgery, or cosmetic reconstruction, for the treatment of wrinkles on the hand, face, or décolleté, or for increasing volume, for example in the case of (HIV-induced) lipoatrophy of the breasts, and for the treatment of selected diseases, including gastrooesophageal reflux disease, urinary incontinence or vesicoureteral reflux disease.
Owner:CELLMED
Use of pharmaceutical composition containing epidermal growth factor (EGF) for diabetic foot amputation prevention
ActiveUS20050107294A1Prevents amputationAssisting in limb preservationOrganic active ingredientsPowder deliveryAngiologyDiabetic foot
The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and / or microvasculature, patients with inadequate lymphatic and / or venous return and ulcers or other lesions which are difficult to cicatrise and / or heal.
Owner:CENT DE ING GENETICA & BIOTECNOLOGIA
Method and apparatus for reconstructive surgery
A method of biological reconstruction and a device having a major chamber or compartment in the form of the desired anatomy with a shaped chamber inside the main chamber flipped up and held in place by one or more inflatable piston chambers. The inflatable piston chambers selectively hold the shaped chamber and are pressurized in order to support the shape of the device upon implantation. Valves are provided to allow filling the major chamber, the shaped chamber and the piston chambers with a biologically compatible fluid.
Owner:CREATIVE IMPLANT DESIGNS
Physiologic tricuspid annuloplasty ring
ActiveUS20120071970A1Reduce constraintsReduce morbidityAnnuloplasty ringsTubular organ implantsAnatomical structuresOut of plane motion
A prosthetic tricuspid remodeling annuloplasty ring for use in tricuspid valve repairs to provide annular support after reconstructive valve surgery. The ring maintains an optimal annular dimension to prevent excessive dilatation of the natural valve annulus while adapting to the dynamic motion of the tricuspid annulus during the cardiac cycle. An exemplary ring features a waveform contour and may be constructed of a titanium core having a varying cross-section for selective flexibility for good Z-axis or out-of plane movement. The “waveform” contour and selective flexibility of the different segments of this ring are designed to adapt to the complex motion of the annulus. This reduces the stress on the anatomical structures and therefore minimizes the risk of arrhythmia and ring dehiscence.
Owner:EDWARDS LIFESCIENCES CORP
Fluorinated 4-azasteroid derivatives as androgen receptor modulators
Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. They are useful as agonists of the androgen receptor in bone and / or muscle tissue while antagonizing the AR in the prostate of a male patient or in the uterus of a female patient. These compounds are therefore useful in the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, cancer cachexia, muscular dystrophies, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.
Owner:MERCK SHARP & DOHME CORP
N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
InactiveUS20050277681A1Minimal effectReduce decreaseBiocideNervous disorderGlucocorticoidAutoimmune disease
Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis, periodontal disease, bone fracture, bone damage following bone reconstructive surgery, sarcopenia, frailty, aging skin, male hypogonadism, postmenopausal symptoms in women, atherosclerosis, hypercholesterolemia, hyperlipidemia, obesity, aplastic anemia and other hematopoietic disorders, inflammatory arthritis and joint repair, HIV-wasting, prostate cancer, benign prostatic hyperplasia (BPH), abdominal adiposity, metabolic syndrome, type II diabetes, cancer cachexia, Alzheimer's disease, muscular dystrophies, cognitive decline, sexual dysfunction, sleep apnea, depression, premature ovarian failure, and autoimmune disease, alone or in combination with other active agents.
Owner:MERCK SHARP & DOHME CORP
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