3067results about "Package sterilisation" patented technology

A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.

A surgical cutting and fastening instrument that includes an elongate channel that is attached to a handle assembly by an elongate shaft assembly. The elongate channel is configured to receive a cartridge and has a pivotally translatable anvil attached thereto and a knife bar supported therein. The anvil may be selectively opened and closed by manipulating a closure trigger supported by the handle assembly. The knife bar may be distally advanced through the elongate channel by actuating a firing trigger that cooperates with a reversible rotary drive supported by the handle assembly. The knife bar may also be retracted to its starting position by actuating the firing trigger after the reversible rotary drive has been shifted to a retraction orientation.

A packaging system providing for sterile enclosure of devices including medical devices and systems such as delivery systems is described. The packaging system is comprised of a primary chamber and includes at least one vent or opening covered by a barrier.

The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.

A base of a container including a bearing surface, a hinge, a first wall, and a second wall. The first wall sloping in a first direction from the bearing surface to the hinge, and the second wall sloping in a second direction away from the hinge. The second wall is adapted to be repositioned about the hinge with substantially no movement of the first wall.

A method of manufacture for a drug cartridge assembly. The method includes providing a drug cartridge, providing a nozzle sub-assembly, and sterilizing the drug cartridge and nozzle sub-assembly. The method further includes assembling the drug cartridge and nozzle sub-assembly together in a configuration that enables ejection of liquid out of the drug cartridge through the nozzle sub-assembly. The method further includes filling the drug cartridge with a liquid, such as an injectable drug. The method may include separate sterilization of the drug cartridge and nozzle sub-assembly, using different sterilization processes. Portions of the method may be performed prior to sterilization within a first cleanroom, with subsequent steps being performed in a second cleanroom having a substantially lower particulate-per-volume rating than the first cleanroom.

The invention is directed to the treating, e.g. sterilizing and packaging of medical devices and other articles, particularly such devices and articles which are reactive to oxygen or moisture containing atmospheres. The sterilized package has a container which includes at least one portion which is gas permeable and at least one portion which is gas impermeable and an interior in fluid communication with the gas permeable portion. The container may be sealed by applying an impermeable patch to the permeable portion thereof or by disposing the container in an enclosure formed of impermeable material and sealing the enclosure. After exposing the container to a sterilizing gas, the gas permeable portion may be removed or sealed off from the gas impermeable portion of the container in order to provide a package which is gas impermeable and can protect one or more articles within the interior of the container against environmental gases and moisture.

Systems, methods, and devices for preparation of purified water and medicaments for various uses including blood treatment are described. Methods, devices, and systems for creating multiple-treatment batches are described.

A packaging system having an outer container and a segment panel defining a plurality of phase change material (PCM) segments, with said segments being aligned with sides of the outer container interior upon wrapping around a payload and insertion into the outer container. The segmented panels may include edge tapers which facilitate the wrapping process with adjacent edge tapers being brought together during the wrapping process. A method of packaging using PCM-containing segments which are wrapped around a portion of a payload is also disclosed.

A container and method are provided for storing fat containing liquid products, such as infant or baby formula, or other milk-based products. The container includes a body defining a storage chamber for receiving the aseptic fat containing liquid product, and a first aperture in fluid communication with the storage chamber. The body does not leach more than a predetermined amount of leachables into the fat containing liquid product and does not undesirably alter a taste profile of the fat containing liquid product. A container closure assembly includes a stopper receivable within the first aperture for hermetically sealing the storage chamber. The stopper includes a first material portion defining an internal surface in fluid communication with the storage chamber forming at least most of the surface area of the container closure that can contact any fat containing liquid product within the storage chamber and that does not leach more than a predetermined amount of leachables into the fat containing liquid product or undesirably alter a taste profile of the fat containing liquid product. A second material portion of the stopper either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area of the container closure that can contact any product within the storage chamber in comparison to the first material portion. The second material portion is needle penetrable for filling the storage chamber with product, and a resulting needle aperture formed in the second material portion is thermally resealable such as by the application of laser energy to seal the product within the storage chamber. A sealing portion of the container closure is engageable with the body prior to needle filling the storage chamber to thereby form a substantially dry hermetic seal between the container closure and body.

Devices are provided for manipulating tissue during a surgical procedure. In certain embodiments, an end effector is operably coupled to the end of an elongate shaft. The end effector has at least one tissue support linkage movably coupled thereto such that upon application of a first actuation force thereto, the tissue support linkage moves laterally outward from within the end effector to enable the surgeon to manipulate/support adjacent tissue therewith. Upon application of another actuation force to the tissue support linkage, the tissue support linkage is caused to move substantially completely within the outer perimeter of the end effector to enable the end effector to be inserted through a lumen/opening or passageway. In various embodiments, the end effector may be selectively articulateable relative to the elongate shaft.

A sterilization system comprising: radiation source; optical and/or electrical sensors; and timing means; wherein the measurement of radiation by the optical sensor is substantially synchronized based on the timing means to the start and end of each pulse of radiation from the radiation source or to the start and end of the exposure of a product to the radiation source.

The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.

An inventive method, system and apparatus are provided for syringe handling, and more particularly, for syringe labeling, filling and capping operations. To facilitate syringe handling, an inventive apparatus includes a plurality of syringe bodies interconnected in a predetermined orientation by a belt. Such belt may be of pliable construction and may define a predetermined spacing in between adjacent ones of the syringe bodies, such predetermined spacing corresponding with a distance between holders provided in a handling apparatus. The syringe handling apparatus may provide for the placement of contents-related information on belt segments between adjacent syringe bodies and for separating the belt segments, wherein a flap is left interconnected to each syringe body. The syringe handling apparatus may alternatively or also provide for automated filling of the syringe bodies wherein cap removal, filling and cap replacement operations are completed free from manual handling.

A sterile device immersed in a sterile buffer and a method for providing same. The sterile device may be a medical device such as a biosensor having a biomolecule as a sensing element such as, for example, a glucose oxidase enzyme. The buffer may be a bicarbonate solution. Both the device and the buffer may be packaged and stored over long term while maintaining sterilization. The sterilization method may comprise a combination of gaseous, liquid and light sterilization.

A multi-layered wound dressing includes a moisture-retaining portion for enhancing the healing of a wound. The wound dressing includes an intermediate layer that has both water soluble and water insoluble fibers. An apparatus that includes a cutting tool and a reservoir of liquid to pre-moisten a portion of the dressing may be used to manufacture the dressings.

A cartridge for an e-vaping device includes an ethanol-free gel formulation. The ethanol-free gel formulation includes a vapor former, water, and a biopolymer. The biopolymer may be included in an amount ranging from about 0.01% by weight based on the weight of the ethanol-free gel formulation to about 2.0% by weight based on the weight of the ethanol-free gel formulation. The biopolymer may be one or more of agar, kappa carrageenan, gelatin, sodium alginate, gellan gum, pectin, and combinations thereof. The cartridge also includes a heater configured to heat liquid from the gel formulation to a temperature sufficient to release a liquid/semi-liquid component from the gel, which component thereupon forms a vapor.