3201results about "Ampoule syringes" patented technology

An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver / hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and / or via wireless communication.

An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver / hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and / or via wireless communication.

A drug solution filling plastic ampoule having gas, steam and light ray barrier properties, a drug permeation preventing capability and an absorption / adsorption preventing capability, and a production method for the plastic ampoule. The drug solution filling plastic ampoule includes a container body, a fusion-bonded portion which seals a mouth of the container body, and a wrench-off holder tab connected to the fusion-bonded portion. The ampoule is formed from a parison including two or more layers, at least one of which is a functional layer having at least one characteristic property selected from the group consisting of a gas permeation preventing capability, a steam permeation preventing capability, a light ray permeation preventing capability, a drug permeation preventing capability and a drug absorption / adsorption preventing capability.

A medication delivery pen having a magnifier, a spring biased leadscrew and a mechanism to allow the user to easily reset the dose on the medication delivery pen if the user requires a smaller dose than has been set.

The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.

An automated injection module is comprised of a housing, a piston drug capsule disposed within the housing, a piston core including a puncture seal membrane defining a reservoir for holding a drug between the puncture seal membrane and the piston drug capsule, an injection device having at least one sharp end for puncturing the puncture seal upon activation of the device, an end cap on a distal end of the housing, and a pressure source on a proximal end of the housing. The pressure source is preferably a propellant that ignites and forces the piston toward the distal end. Substantially simultaneously, the injection device pierces the puncture seal membrane, the piston core is forced into the piston drug capsule, and the drug is evacuated from the reservoir through the injection device and into a patient.

A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

The invention relates to an impulse chamber which can be used for expelling an amount of a fluid compound at a high pressure. The impulse chamber comprises a variable-volume impulse chamber adapted for containing a volume of a flowable drug, an outlet nozzle in fluid communication with the impulse chamber and being adapted to be arranged against the skin of a subject, and a fluid inlet in fluid communication with the impulse chamber. The impulse chamber is defined substantially by a deformable chamber portion, such that deformation thereof reduces the volume of the cavity. In an exemplary embodiment the compressible chamber portion is in the form of an elastomeric tube, this providing a simple, yet reliable and cost-effective impulse chamber unit.

The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and second time stamps. The device further comprises control means for setting a first time stamp in response to the contact means being operated between first and second conditions, setting a second time stamp in response to the contact means being operated between the second and first conditions, calculating the time elapsed between the two time stamps, comparing the elapsed time with a preset time value, and performing a control action if the elapsed time is greater than the preset time value.

A jet injector system for injecting fluid into a body. The jet injection system includes capsules for holding the material to be injected, apparatus for applying force to the capsule(s) to eject the injection material(s) and a perforator for directing the jet stream for the respective materials into the body. A flyweight system is described for developing jet injection pressures, and latching devices control the flyweight system. An injector system for injecting more than one fluid is described.

A medication dispensing apparatus that provides a mechanical advantage. During dose preparing, a nut rotating element (410) and a screw element (368) are in a first axial arrangement such that a screwing motion of the nut rotating element and screw element relative to the apparatus housing that moves the elements a first axial distance from a home position screws a nut (364) along a drive member threaded shaft (362) a second axial distance different than the first axial distance. During dose dispensing, the nut rotating element and the screw element are in a second axial arrangement, whereby a screwing motion of the screw element relative to the housing back toward the home position advances a plunger (366) in the distal direction to axially advance the nut and thereby the drive member and a fluid container piston to dispense medicine.

An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.

A device comprises a housing having a mounting surface adapted for application to the skin of a subject, a needle with a pointed end portion adapted to penetrate the skin the subject, the needle having a first position in which the distal end portion is retracted within the housing, and a second position in which the distal end portion projects relative to the mounting surface. The device further comprises actuatable driving means actuatable to cause activation as well as release of the driving means, thereby moving the needle from the first position to the second position. By this arrangement the needle device can be supplied to the user in a non-energized state, the energizing taking place when the device is actuated by the user which means that energy will be stored only for a period from a few seconds to a few hours or days.

A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.

An injection device having an elongated body, including a container with medicament, elements for connecting a needle to the container, actuating elements capable of injecting a dose of medicament upon activation, activating elements capable of activating the actuating elements, a needle shield arranged to the body and slidable between an extended and a retracted position in relation to the body. The needle shield is designed and arranged such that, upon penetration of the needle into a patient, when moved to its retracted position, acts on the activating elements, which in turn activates the actuating elements and injects a dose.

An improved luer lock receiving septum having a configuration which provides rapid and tight resealing and yet allows penetration of the septum by the luer tip with a low penetration force. The elongated septum includes an upper portion of enlarged diameter having a target surface, a central slit, and a central, lower septum extension projecting about the slit below the upper portion and into a housing so that following luer insertion there is provided sufficient room for both the laterally displaced extension of the septum, the luer taper, and the housing to be received into a conventional luer lock connector. The septum is further preferably configured to minimize or eliminate the negative pressure deflection normally associated with the withdrawal of the large diameter luer cannula from an enclosed fluid filled lumen or chamber, by substantially isolating the lumen or chamber from the septum material displacement resultant from luer insertion. In an exemplary embodiment, the luer receiving septum is provided at a port of a stop cock.

There can be provided a sealing stopper for a syringe, having very high sealing property and sliding property, and a prefilled syringe using this sealing stopper and capable of preserving a medicament for a long time and operating in easy and precise manner during injecting. This syringe is also excellent in sanitary and operating property during a step of formulation or preservation of a medicament. In this sealing stopper for a syringe, a surface of the rubber body is laminated with a tetrafluoroethylene resin film or ultra-high molecular weight polyethylene film having an average roughness Ra on the central line of the surface in a range of at most 0.05 mu m and a kinematic friction coefficient of at most 0.2.

A transdermal drug delivery device for forming a micropore in a tissue membrane of an animal comprising a substrate and a porator that is located on or within the substrate. The porator is constructed of a material that is destroyed upon forming the micropore. The transdermal drug delivery device also comprises at least one reservoir and a controller for controlling the formation of said micropore by the porator and destroying the porator after the formation of the micropore.

A needle tip protective device for use with percutaneous entry needles. In one embodiment, the needle tip protective device includes a needle guard slidably mounted on a hypodermic needle, the latter having a needle tip located at the distal end thereof, and a change of profile formed medially there along. The needle guard is movable along the hypodermic needle and engageable with the change in profile formed thereon. The engagement with the change in profile is configured to correspond with the ability of the needle trap to entrap the needle tip once the needle trap has advanced the sufficient distance distally along the hypodermic needle. In further refinements, the needle trap may be biased toward the distal needle tip of the needle.

A medical device for managing tissue in an organ, such as the stomach, for retracting or positioning tissue and related organs to allow certain regions of the stomach to be acquired for a gastroplasty procedure. The medical device includes an elongated body having a proximal end and a distal end, and a retractor section disposed at or near the distal end. The retractor section is adapted to be moveable from a delivery position to a retraction position to move or manage the tissue of the stomach. The retraction device can be configured for use with a second therapeutic device or such a therapeutic device may have a retraction device integrated within it or adapted for cooperative use therewith.

A device for painlessly injecting medications, and a method for providing a substantially painless injection of medication into a patient that does not require the use of an anesthetic, that does not require the medical personnel to spend a substantial amount of time performing the injection procedure, that is relatively simple and inexpensive to perform and operate, and that provides a relatively high degree of safety for both the medical personnel and for the patient. The injection needle can have an outside diameter greater than 0.20 mm and less than about 0.38 mm. The medicament can be injected painlessly through the needle and into the patient at a substantially constant volumetric flow rate of about 0.05 μL / s to about 50 μL / s.

A medication dispensing apparatus having a gear set (64) to provide a mechanical advantage to the plunging of the apparatus plunger (66). The gear set (64) has a first pinion (114) in meshed engagement with a rack of the plunger (102), and a second pinion (126) in meshed engagement with a rack of a drive member (80) of the apparatus. The gear set (64) operatively interconnects the plunger (66) and the drive member (62) such that after the plunger (66) is moved relative to the housing in a proximal direction to prepare the apparatus for injection, the plunger (66), when manually pushed back toward the housing, causes the drive member (62) to advance in a distal direction to force medication through an outlet, typically provided with an injection needle, at the distal end of the apparatus.

The present invention provides a device for administering an injectable product in doses, the device including a casing, a container accommodated by the casing, a delivering appliance for delivering the product from the container, a drive for the delivering appliance, and a means for determining a malfunction of the device, wherein a vibrator motor is accommodated by the casing, the vibrator motor being triggered by the means for determining a malfunction such that it generates a vibrating alarm signal when a malfunction is determined.

A safety shield system for a needle cannula of a pen needle injector or similar device, wherein a safety shield may be retracted from a first position enclosing the needle cannula to a second position exposing the needle cannula for injection. The safety shield system permits retraction of the safety shield during use, but extends the shield enclosing the needle cannula in a locked position following use. The shield system is utilized with a pen needle injector having a double-ended needle cannula mounted in a hub member received on an open end of the pen needle injector. The assembly is disposed of by removing the system and storing the assembly in the cup-shaped top cap enclosing the exposed end of the needle cannula within the cap. The top cap includes internal radial ribs preventing retraction of the shield prior to removing the top cap preventing inadvertently piercing the top cap during assembly. In addition, a bottom cap may be interlocked to the top cap to completely encompass the needle cannula, thereby ensuring safe disposal of the assembly.

A medication delivery pen is provided having a lead screw with an enlarged portion at a first end thereof and an end longitudinally opposite the first end in contacting engagement with a plunger of a medication cartridge. The lead screw is selectively axially displaceable by a user when selectively administering a predetermined dosage amount of medication for injection into a patient. The medication delivery pen also includes a driver coaxially disposed about the lead screw; and, a reset ring non-rotatably disposed on the driver and axially slidable thereon and therealong. The reset ring is axially movable with respect to the driver when a dosage amount is set by a user of the medication delivery pen. The reset ring engages the enlarged portion of the lead screw upon a predetermined extent of relative axial movement between the reset ring and the lead screw. With this arrangement, the reset ring advantageously prevents setting a dose on a medication delivery pen that is greater than the medication which is available.

A syringe type apparatus which includes a unique fill assembly for use in controllably injecting medicinal fluids into a patient. The filling assembly includes a prefilled vial which is partially received within a novel adapter assembly that functions to operably couple the prefilled vial with the syringe assembly of the apparatus. The body of the prefilled vial is surrounded by a protective covering until immediately prior to mating the assembly with the syringe assembly.

An automatic injection and retraction device having a longitudinal axis is provided that includes an injection assembly, a retraction assembly, and a pre-filled syringe cartridge. The injection assembly has an activation-prevention feature moveable between an on position and an off position. The retraction assembly has a needle guard that is removable in a direction along the longitudinal axis upon application of a removal force. The pre-filled syringe cartridge has a hypodermic needle with a needle sheath thereon. The retraction and injection assemblies are secured to one another so that the pre-filled syringe cartridge is in the retraction assembly with the needle sheath secured to the needle guard. The retraction and injection assemblies are configured so that, upon application of a twisting torque to the injection and retraction assemblies, the activation-prevention feature moves from the on position to the off position simultaneous with applying the removal force to the needle guard.

A hand-held, electronically controlled injection device (1) for injecting preset doses of liquid medications, having a housing (2) for receiving a cartridge (4) containing the liquid medication and having a contact surface (16) for contacting a patient's skin; and actuator elements (41) for moving the cartridge (4) within the housing (2) to and from the contact surface (16).

A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the outside surface of the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. The safety shield has a number of protrusions guided in guiding tracks on the outside surface of the needle hub. The guiding tracks are designed such that the safety shield during injection is moved towards the needle hub, and after injection is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries.