179 results about "Prefilled Syringe" patented technology

A spiral excitation assembly of a prefilled automatic injection pen and a prefilled automatic injection pen comprising the spiral excitation assembly. The spiral excitation assembly of the prefilled automatic injection pen comprises: a cavity (6) for changing a rotary motion of a threaded push rod (5) into an axial forward movement; a nut (9), which is capable of being rotatably mounted in the cavity (6) relative to the cavity (6), with a torsion spring (7) capable of driving the nut (9) to rotate being arranged between the nut (9) and the cavity (6); the threaded push rod (5), which is in threaded connection with the interior of the nut (9) and driven by the rotation of the nut (9) to move forward and then drive a prefilled syringe (4) to move to complete automatic needle insertion; a clutch member (10), which is sleeved outside the nut (9) and capable of being driven by an excitation sleeve (3) of the prefilled automatic injection pen to move from an engaged position to an excitation position, wherein the clutch member engages with the nut (9) to stop the nut (9) when in the engaged position, and the nut (9) can rotate when the clutch member is in the excitation position; and a clutch spring (8), which is mounted between the clutch member (10) and an end cover (11) and is used for driving the clutch member (10) from the excitation position into a limiting position to limit backward movement of the excitation sleeve (3) to achieve needle protection post-injection, and to cause the clutch member (10) to collide with the nut (9) to produce a sound.

The invention discloses an auxiliary device for preventing an injector from needling. The auxiliary device aims to solve the problems that an existing passive protection device is prone to being started by mistake, a push rod is prone to inclining, protection is not achieved after injection, and adaptability is poor. The device comprises an outer shell, a compression spring, an inner shell, a disposable prefilled syringe and a push rod. The shell is an external support and is provided with a guide bone position, an elastic step, a guide channel, an elastic buckle and the like; the inner shell is assembled in the outer shell, bears the injector and is connected with the compression spring; the push rod is in threaded connection with the syringe piston, and the actuating rod is inserted into the shell guide channel. The device realizes single-hand operation and automatic protection, does not need an additional activation step, is adaptive to a medicine production process, effectively reduces the risk of pricking injury, and avoids waste of liquid medicine. And the clinical use safety and the operation convenience are improved.

The disposable injection pen comprises an upper pen shell assembly and a lower pen shell assembly which are assembled and matched, the lower pen shell assembly comprises a pen cap and a protective shell clamped in the pen cap, and a bracket for supporting a pre-filled syringe is arranged on the inner ring of the protective shell; a pen cap spring extending towards the bracket is arranged on the pen cap; and the pen cap spring is in pressing fit with the axial edge of the needle protecting cap. According to the lower pen shell assembly, a protective shell installed in a pen cap lifts and supports a bracket, a pre-filled syringe can be fixedly installed in the bracket, a pen cap spring is arranged in the pen cap, the axial edge of a needle protecting cap is pressed and matched through the pen cap spring, the pen cap of a spring structure is arranged, the spring is pressed on the circumferential edge of the needle protecting cap, and therefore the pre-filled syringe can be fixed to the bracket. Therefore, the needle protecting cap is subjected to axial pulling-out acting force, the clamping structure is stable, and smooth pulling out of the needle protecting cap is guaranteed.

According to the double-cavity prefilled syringe with the equal-diameter channels and the prefilling method, firstly, a middle piston is installed through mechanical plugging, then sterile powder in a first medicament cavity is filled, and after a rubber gasket, a Luer lock adapter and a protective cap assembly are assembled, sterile powder is filled in the first medicament cavity in a pressing mode; the Ruhr lock adapter annular buckle is guided by the auxiliary conical surface to be fixed to the limiting groove, at the moment, the rubber gasket is pressed by the mechanical sealing structure, meanwhile, the protective cap assembly seals the Ruhr lock medicine outlet, and a cavity close to the medicine outlet is well sealed. Then the double-cavity pre-filling syringe is turned over, the solvent is filled from a flange inlet, filling of the second medicament cavity is completed, a push rod piston is installed through mechanical plug adding, and a cavity far away from a medicament outlet is well sealed. According to the invention, the two ends of the needle cylinder are adopted to realize pre-encapsulation administration, so that the administration residue or pollution can be avoided, and the rubber gasket, the Luer lock adapter and the protective cap assembly are matched to realize high-precision sealing.

A disposable syringe unit for an injection device adapted for releasable attachment to a reusable drive unit of the injection device includes a prefilled syringe with a reservoir and an injection needle, a syringe holder for holding the prefilled syringe, a cover member guided by guiding means thereby movable along the longitudinal axis relative to the syringe holder between a covering position in which the injection needle is covered and a retracted position in which the injection needle protrudes from the cover member, and a cap releasably attached to a distal end of the cover member or the syringe holder. Apart from the prefilled syringe, the syringe unit includes in total not more than three separate parts.

The invention relates to the technical field of pre-filled medicine bottles, in particular to a device for providing needle hiding and post-injection needle puncture-proof protection and a pre-filled syringe, the device comprises a needle hiding sleeve, a medicine bin shell, a locking sleeve, a medicine bottle support and a locking sleeve ejector rod, and the needle hiding sleeve is arranged in the medicine bin shell; a locking sleeve is arranged above the needle hiding sleeve, a medicine bottle support is arranged in the locking sleeve, and a pre-filled medicine bottle is arranged in the medicine bottle support; the bottom of the locking sleeve and the upper portion of the needle hiding sleeve are mutually embedded, and a locking sleeve ejector rod is arranged above the medicine bottle support. When injection is not carried out, the locking sleeve and the needle hiding sleeve can move freely; after injection is completed, the locking sleeve is locked by the locking sleeve ejector rod, so that the hidden needle in the pre-filled medicine bottle cannot be exposed. No matter whether the device is connected with a host or not, the needle head can be hidden when injection is not carried out, removal of the hidden needle protective cap is not affected, and friendly experience is provided for a user fear of needle fear; after injection, the hidden needle sleeve is locked, the hidden needle is prevented from being exposed, a needle head is prevented from stabbing related personnel, and the use safety is improved.

A polymer double-cavity prefilled syringe comprises a barrel with a bypass, the barrel is provided with a finger handle and an adapter, a needle seat is arranged on the adapter, a needle body is fixed on the needle seat, and a protective cap is arranged on the outer side of the needle body. A front plunger, a middle plunger and a rear plunger are arranged in the barrel, and the rear plunger abuts against a plunger rod. The cylinder is formed by integral injection molding of polymer, a group of ribs which are arranged side by side and protrude towards the interior of the cylinder are arranged on the inner wall of the cylinder, the axial length of each rib is larger than that of the middle plunger, the bypass is formed by a gap between every two adjacent ribs, and the outer diameter of the cylinder is larger than that of the adapter; the protective cap is tightly connected with the needle seat, a first anti-falling mechanism is arranged on the joint face of the protective cap and the needle seat, and an inner cavity of the protective cap is communicated with the outside through a bacteria-blocking, hydrophobic and breathable filter membrane. The bypass is formed in the mode that the protruding edges protrude inwards, demolding is convenient, integrated injection molding machining can be conducted through polymers, cost is low, damage is not prone to occurring, and the using effect is good. The outer surface of the cylinder is smooth, the heat conduction performance is good, and the vacuum freeze-drying efficiency is high.

The invention provides a disposable injection pen and an injection prompt structure thereof, the injection pen is characterized in that an upper pen shell assembly drives a pre-filled syringe in a lower pen shell assembly to realize an injection function, a rotary sleeve and a screw rod which are rotatably matched are arranged in the upper pen shell assembly, and the injection function of the syringe is completed by axially pushing the screw rod; according to the technical scheme, the sound part which synchronously rotates is arranged on the rotating sleeve, and at the tail end of injection work execution, the sound part axially slides relative to the rotating sleeve and collides with the rotating sleeve in the sliding process to make a prompt tone so as to prompt that injection is completed; the prompt tone of injection completion can be accurately prompted, and the user experience is improved.

An apparatus includes a housing, a medicament container and a movable member. The medicament container is movable within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member exerts the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member exerts a retraction force on the flange to move the medicament container from the second position towards the first position.

According to the disposable injection pen and the injection unlocking structure thereof, a pre-filled syringe is assembled in a lower pen shell assembly and is driven by a driving device in an upper pen shell assembly to conduct injection, in the injection process, the lower pen shell assembly drives a rotary sliding block in the upper pen shell assembly to move upwards so that an injection needle can be exposed, the rotary sliding block slides on a fixed sleeve, and therefore the injection needle can be unlocked. The driving device in the upper pen shell assembly is unlocked in the sliding process, the rotary sliding block which is rotatably arranged axially slides before reaching the unlocking position, and the rotary sliding block rotates after reaching the unlocking position and collides with the fixed sleeve to make an unlocking prompt tone, so that a user can accurately know the injection starting condition; and the subsequent injection action can be accurately carried out.

According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slidably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

The invention discloses a dexmedetomidine and propofol combined reagent and a combination method, and relates to the technical field of combined use of anesthetic drugs. According to the method, firstly, dexmedetomidine is subjected to intravenous pump injection within 5-15 minutes according to the dosage of 0.5-1.0 mu g / kg, propofol is given within 2 minutes after the dexmedetomidine is subjected to general anesthesia, and the dosage of the propofol can be reduced by 10%-50% compared with that of propofol which is independently used. Through pretreatment of dexmedetomidine, the anesthetic effect of propofol can be enhanced, adverse reactions such as blood pressure drop and respiratory depression can be effectively reduced, and anesthetic safety and controllability are improved. The combined reagent comprises independent containers for respectively loading the dexmedetomidine injection and the propofol emulsion, and can be packaged by adopting a double-cavity pre-filled injector, and sequential injection is realized through a controllable opening mechanism, so that unstable emulsification and titer change caused by physical mixing of medicines are avoided.

The invention relates to the field of injection devices, in particular to a puncture-proof protection device and a pre-filled syringe, the puncture-proof protection device comprises a medicine bin shell, a needle hiding sleeve, a needle hiding connecting rod, a connecting rod spring, a medicine bottle support, a medicine bottle gland, a needle hiding limiting piece and a pre-filled medicine bottle; the needle hiding sleeve and the needle hiding connecting rod are connected and arranged in the medicine bin shell, and the needle hiding limiting piece and the medicine bin gland are sequentially arranged at the end, away from the needle hiding sleeve, of the needle hiding connecting rod. A shifting block is arranged on the needle hiding limiting sheet; the shifting block drives the hidden needle limiting piece to rotate to limit or release the axial movement of the hidden needle connecting rod; the needle-hidden connecting rod and the pre-filled medicine bottle are sleeved in the medicine bottle bracket, and a connecting rod spring is arranged between the needle-hidden connecting rod and the medicine bottle bracket; the needle hiding sleeve is fixed by clamping the needle hiding connecting rod and the needle hiding limiting piece, so that the needle head is prevented from being exposed out of the needle hiding sleeve, and the needle head is prevented from being accidentally injured. Reset is achieved through device elasticity, the process is simple and convenient, the automation degree is high, and user operation difficulty is low.

An apparatus includes a housing, a medicament container and a movable member. The medicament container is movable within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member exerts the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member exerts a retraction force on the flange to move the medicament container from the second position towards the first position.

1. The name of this design product: two-color prefilled syringe. 2. Purpose of this design product: for drug injection. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The utility model discloses a pre-filled syringe for sealing an infusion port tube, which can directly perform tube sealing operation after tube washing through an integrated injection structure, avoids many problems of syringe switching, avoids reverse flow of tube washing liquid or tube sealing liquid in the process, and can assist medical staff in automatically realizing a pulse type injection technique. According to the technical scheme, the catheter flushing device is characterized by comprising a pipe flushing cavity, a pipe sealing cavity and a butt joint opening, the pipe flushing cavity and the pipe sealing cavity are arranged side by side, scale marks are arranged on the outer wall of the pipe flushing cavity and the outer wall of the pipe sealing cavity, the butt joint opening is communicated with the interiors of the pipe flushing cavity and the pipe sealing cavity at the same time and can be connected to the tail end of an existing catheter, and a pipe flushing rod and a first piston are arranged at the pipe flushing cavity; a pipe sealing rod and a second piston are arranged at the position of the pipe sealing cavity, one-way valve structures are arranged between the pipe washing cavity and the butt joint opening, one-way valve structures are arranged between the pipe sealing cavity and the butt joint opening, the device further comprises a limiting piece used for limiting the displacement state of the pipe washing rod, and when the pipe washing rod moves by a specific distance, the limiting piece temporarily limits continuous movement of the pipe washing rod.

The present invention belongs to the technical field of medical instruments, and in particular, relates to a prefilled syringe with a protective cover, and its components, component assembly method, and drug filling method. The present invention includes a syringe, a mounting portion, and an injection needle, and also includes a protective cover unit sleeved on the syringe body, a syringe ridge arranged on the needle mounting tube and used to engage the protective cover unit, and a needle cover unit sleeved on the needle mounting tube and located in the protective cover unit, and used to release the protective cover unit from the syringe ridge in the opening direction. The needle cover unit has a technical effect of stably covering the needle to avoid exposure after the injection is completed. The advantage of the present invention is that the protective cover and the syringe are designed as an integrated unit, and the protective cover can be opened and the needle can be exposed by a one-step upward push operation. After unlocking the protective cover, the needle cover can be taken off, and the protective cover is locked with the syringe ridge when it returns to the initial position, and a ticking prompt sound is generated during the locking process of the protective cover and the syringe ridge.

The purpose of the present invention is to provide a pre-filled syringe formulation with staked needle, which contains an antibody at a high concentration and can be produced on an industrial scale in a simple manner without causing clogging. A pre-filled syringe formulation with staked needle, in which a protein solution is packed. The pre-filled syringe formulation is characterized in that a cap formed with a material having low water vapor permeability is provided at the needle.

The invention relates to an automatic injection pen for a pre-filled syringe, which comprises a pre-filled syringe PFS, the PFS is mounted in an automatic injection device, and the automatic injection device comprises an outer pen shell, an excitation unlocking sleeve, a needle retracting spring base and a syringe; the fixed part of the narrowing spring base penetrates through the excitation unlocking sleeve to be connected with the outer sleeve; the narrowing spring base is fixed in the outer sleeve; a narrowing spring is mounted on the upper part of the narrowing spring base, and a syringe is mounted on the narrowing spring base in a releasable manner; before injection, the PFS is connected with the outer sleeve through the narrowing spring base; and the needle head of the PFS penetrates through the narrowing spring base, so that the puncture part of the needle head crosses the bottom of the outer sleeve. According to the invention, the structure of the needle retracting spring base is improved, so that the needle head of the PFS can move downwards along with the outer sleeve in the needle puncturing process, and the puncturing process is more controllable and reliable.

The invention relates to the technical field of medicine packing materials, in particular to a filling process of a novel aripiprazole double-cavity pre-filling syringe, and a syringe barrel of the novel double-cavity pre-filling syringe is made of COP / COC materials; comprising the following steps of sterilization, middle plug placement, sterile filling, freeze drying, plug pressing and assembling, and a complete double-cavity pre-filled syringe is obtained.The filling process combines high strength and heat conduction uniformity of COP / COC materials, in-situ freeze-drying in the syringe is achieved, the step of powder transfer after freeze-drying of a traditional penicillin bottle is avoided, and the production efficiency is improved. According to the present invention, the sterile risk and the production cost are significantly reduced, the manufacturing process is simplified, the equipment complexity and the product loss are reduced, and the high dose accuracy and the yield are ensured.

A prefilled syringe safety device and injector for use with a syringe. The prefilled syringe safety device and injector includes a cartridge, a casing, a tube, a biasing member, a ring and a plunger slider. The cartridge supports the syringe therein. The cartridge is supported within the casing. The tube includes a tube distal end. The tube is slidably engaged with the cartridge and can be in an extended state and in a retracted state. When in the retracted state, the needle of the syringe extends beyond the tube distal end and the casing distal opening. The biasing member is engaged with the cartridge and the tube to bias the tube in the extended state. The ring includes a protrusion and is engaged with the tube and the biasing member. The protrusion is positioned within the track. The plunger slider engages with the plunger of the syringe.

The device includes a housing, a gas container, a drug container assembly, and a movable seal member, the housing defining a gas chamber and an equalization bypass. The gas container is disposed within the housing and configured to generate pressurized gas in the gas chamber when the device is activated. The movable seal member is configured to move from a first sealing position to a second sealing position. When the movable seal member is in the first sealing position, the gas chamber is in fluid communication with an external volume surrounding the device via the equalization bypass. When the movable seal member is in the second sealing position, the gas chamber is fluidly isolated from the external volume by the movable seal member.

A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.

The invention belongs to the technical field of injector assembling equipment, and provides pre-filled injector assembling equipment which comprises an assembling rotary disc, a clamping assembly, a quantitative ring feeding assembly, a push rod assembling assembly, a first push rod detecting assembly, a piston assembling assembly and a sleeve assembling assembly. A quantitative ring feeding station, a push rod assembling station, a piston assembling station and a sleeve assembling station are arranged in the circumferential direction of the assembling rotary disc. According to the pre-filled syringe assembling equipment provided by the invention, all assembling procedures are annularly connected in series, so that the structure of the device is more compact; in the assembling process, clamping and fixing components and positions do not need to be frequently switched, so that a production line is more concise, and needed equipment is effectively reduced; meanwhile, the clamping assembly is emptied while assembling of the injector is finally completed, the clamping assembly directly enters the next cycle, the assembling process is more concise, and needed equipment is further reduced.

A prefilled syringe safety device and injector for use with a syringe. The prefilled syringe safety device and injector includes a cartridge, a casing, a tube, a biasing member, a ring, and a plunger slider. The cartridge supports the syringe. The cartridge is supported within the casing. The tube includes a tube distal end. The tube is slidably engaged with the cartridge and can be in an extended state and in a retracted state. When in the retracted state, the needle of the syringe extends beyond the tube distal end and the casing distal opening. The biasing member is engaged with the cartridge and the tube to bias the tube in the extended state. The ring includes a protrusion and is engaged with the tube and the biasing member. The protrusion is positioned within the track. The plunger slider extends from the plunger of the syringe.

The invention relates to the technical field of medical syringes, and particularly discloses a pre-filled syringe. The pre-filled syringe comprises a syringe tube, a piston and a push rod, the piston is arranged in the syringe tube in a damping mode, the push rod is connected to the piston, and a connecting tube used for being connected with a needle head assembly is arranged at the bottom of the syringe tube; the pre-filled syringe further comprises a separating plug and a sealing cap, and the sealing cap is connected to the connecting cylinder in a sealed mode. The separating plug is arranged in the syringe and located on the side close to the sealing cap so as to separate the syringe into a first containing cavity and a second containing cavity, the first containing cavity is the area between the piston and the separating plug, and the second containing cavity is the area between the separating plug and the connecting cylinder; a drainage groove is formed in the inner wall face of the second containing cavity and extends to the connecting cylinder in the vertical direction. Therefore, the problems that safe and smooth injection of liquid medicine is difficult to guarantee and liquid medicine residues are caused by the fact that the separation piston is blocked easily in the application process of an easily-folded sealing pre-filling syringe in the prior art are solved.

The present invention provides a disposable injection pen and an injection unlocking structure thereof. A prefilled syringe is assembled in a lower pen housing assembly, which is driven by a driving device in an upper pen housing assembly for injection. During the injection process, the lower pen housing assembly drives a rotating slider in the upper pen housing assembly to move upward to expose the injection needle. The rotating slider slides on a fixed sleeve. During the sliding process, the driving device in the upper pen housing assembly is unlocked. The rotating slider is rotatably arranged and slides axially before reaching the unlocking position. After reaching the unlocking position, the rotating slider rotates and collides with the fixed sleeve to produce an unlocking prompt sound, thereby allowing the user to accurately know the injection start status and accurately perform subsequent injection actions.

Embodiments of the present disclosure relate to systems and methods for the application of vaporized chemicals in the sterilization of medical products. For example, embodiments of the present disclosure may relate to systems and methods for the terminal sterilization of medical products using vaporized hydrogen peroxide (VHP). Embodiments of the present disclosure may relate to, e.g., systems and methods for the terminal sterilization of medical products, such as pre-filled syringes (PFS).

A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.

The invention discloses a prefilled syringe glass needle cylinder flange width cutting device which comprises a base, an X-direction displacement mechanism is installed on the base, a Y-direction displacement mechanism is installed on the X-direction displacement mechanism, a motor support is installed on the Y-direction displacement mechanism, a servo motor, a speed reducer and a transmission shaft are installed on the motor support, and a double-face cam is installed at the tail end of the transmission shaft. The double-face cam comprises a disc-shaped wheel, cam-shaped grooves are formed in the two side faces of the disc-shaped wheel respectively, cam-shaped protrusions with different cam curves are arranged in the cam-shaped grooves respectively, cam curve grooves are formed between the outer contours of the cam-shaped grooves and the outer contours of the cam-shaped protrusions, a left cam curve groove is formed in the left side face of the disc-shaped wheel, and a right cam curve groove is formed in the right side face of the disc-shaped wheel. A right cam curve groove is formed in the right side face of the disc-shaped wheel, and a stroke difference exists between the left cam curve groove and the right cam curve groove. The end face and the two side faces of the glass needle cylinder are machined at the same time through the driving device through the design of the cam curve groove of a special structure and the compact sliding type design.