27 results about "Injection site" patented technology

The invention discloses an administration agent in-vivo release and absorption visualization method based on a CFD-PBM coupling model. The method comprises the following steps: constructing a CFD model of a physiological environment of an injection site; establishing a population balance model (PBM) of the drug particles; the PBM is embedded into a CFD model solver, multi-scale coupling simulation is carried out, and a CFD-PBM coupling model is obtained; the three-dimensional visualization engine dynamically displays drug concentration distribution and particle behaviors; reversely adjusting preparation prescription parameters by using a multi-parameter optimization algorithm; and calibrating model parameters, and generating a key data report. According to the method, the prediction precision and the research and development efficiency can be remarkably improved, and the method is suitable for development of long-acting preparations such as microspheres and implants.

A method comprising validating a carbon dioxide injection operation plan at a carbon dioxide injection site, which comprises creating a first simulation model to simulate flow from the wellhead to a downhole environment and creating a second simulation model to simulate flow dynamics in a reservoir. The method further comprises conducting a carbon dioxide injection test operation based on the carbon dioxide injection plan at the carbon dioxide injection site and monitoring the carbon dioxide injection operation, which comprises measuring real-time data from the wellhead and the downhole, comparing the real-time data with the first simulation model, identifying risks from the comparison between the collected data in the first simulation model, and adjusting the carbon dioxide injection operation and based on the identified risks.

The invention relates to injectable cross-linked collagen gel and a preparation method thereof. Two crosslinking strategies of self-crosslinking and crosslinking agent crosslinking are fused together for the first time, and two types of amido bonds, namely amido bonds of a collagen-collagen structure (A) and amido bonds of a collagen-fatty amine-collagen structure (B), are respectively constructed through two crosslinking paths, namely catalysis of collagen polypeptide self-crosslinking and catalysis of fatty amine crosslinking, so that a hard / soft dual crosslinking network is obtained. The relative proportion of the structure A and the structure B in the final product is adjusted through a proper cross-linking process, so that the strength and the stability of the final product are adjusted and controlled, and the use requirements of different injection parts can be met.

1. The name of the design product: insulin injection simulation artificial skin. 2. The use of the design product: the product is mainly used to demonstrate injection site selection and injection process in subcutaneous injection education process. 3. The design points of the design product: the combination of shape, pattern and color. 4. The picture or photo that best indicates the design points: perspective view. 5. The design for which protection is sought contains color. 6. The back of the design product is a part that is not easy to see or cannot be seen during use, and the rear view is omitted.

The utility model relates to the technical field of zipper production and processing, in particular to a zipper production and processing combination machine. The combined machine comprises a combined machine body, an injection molding opening is formed in the surface of the combined machine body, a protection device is arranged on the surface of the injection molding opening, the protection device comprises two square rods, the two square rods are fixedly connected with the surface of the injection molding opening, and the sides, close to each other, of the two square rods are rotationally connected with rotating rods; the arc surface of the rotating rod is fixedly connected with a protection plate, the surface of the protection plate is fixedly connected with a handle, and the surface of the square rod is fixedly connected with a square block. The problems that when the injection molding opening is not used for a long time, impurities such as dust in air are attached to the surface of the injection molding opening, the dust enters the injection molding portion of the zipper teeth, the shapes of the zipper teeth are possibly irregular, the zipper teeth are not tightly meshed, and therefore the zipper teeth are prone to being disengaged and the zipper is not smoothly zipped when the zipper is used are solved.

This invention relates to an artificial intelligence-based method and system for segmenting ultrasound-guided injection sites, belonging to the field of image processing technology. It includes the following steps: acquiring an image of the ultrasound-guided injection site and annotating the image with a segmentation mask; preprocessing the annotated image; constructing an ultrasound-guided injection site segmentation model, the model including a coarse segmentation module and a fine segmentation module; the coarse segmentation module adopts a U-Net network architecture, and the fine segmentation module includes an edge refinement unit and a second feature fusion unit; inputting the preprocessed image into the ultrasound-guided injection site segmentation model for training; optimizing the model using a loss function during training to obtain a trained model; inputting the image of the ultrasound-guided injection site to be detected into the trained model to obtain the ultrasound-guided injection site segmentation result. This invention can enhance the robustness of the ultrasound-guided injection site segmentation model and improve the accuracy of ultrasound-guided injection site segmentation.

The present invention relates to GIP / GLP1 agonist compositions. The present invention is a GIP / GLP1 co-agonist peptide pharmaceutical composition for subcutaneous injection. The composition comprises tirzepatide, NaCl, and disodium hydrogen phosphate. The composition provides commercially acceptable shelf-life stability, use-life stability, and an acceptable patient injection site experience. An alternative composition comprises tirzepatide, propylene glycol, and disodium hydrogen phosphate, which also provides acceptable shelf-life stability.

The present invention relates to a combination of a first vaccine comprising a non-replicating immunogen of porcine erysipelothrix sp. And a non-replicating immunogen of porcine parvovirus and a second vaccine comprising a non-replicating immunogen of leptospira sp. And the first vaccine and the second vaccine are jointly injected into corium layers of a first injection part and a second injection part of the pig at different points to prophylactically treat the pig so as to resist swine erysipelothrix erysipelas infection, porcine parvovirus infection and leptospirosis infection.

An embodiment of a resettable injection training device is provided including a housing defining a receptacle having an opening, including a top side and a bottom side, a resettable, removable container receivable within the receptacle including a stopper that is movable within the container. The device also includes an actuation member configured to simulate actuation of an injection device, one or more sensors comprising a container sensor for detecting receipt of the container within the receptacle, a safety latch extending from the bottom side of the device, said safety latch for contacting an injection site, and a processor for detecting a condition of the one or more sensors, and optionally, providing feedback based on the condition detected. In a further embodiment, the device includes an adhesive associated with the housing for affixing the housing onto the injection site during use of the device.

The forming apparatus comprises a feed path for continuously feeding a continuous tow material along a transport direction, a forming device connected to a downstream end of the feed path and adapted to form the continuous tow material into a continuous tubular rod. The forming device comprises a tubular element adapted to allow the continuous tow material to pass through the tubular element to form the continuous tubular rod and a steam generator adapted to generate overheated steam. The steam generator is in fluid connection with the tubular element to provide overheated steam to the continuous tow material. The forming device further comprises several fluid conduits to provide overheated steam from the steam generator to several injection sites arranged along a length of the tubular element, wherein at least one fluid conduit of the several fluid conduits comprises a temperature control unit including a temperature sensor and a temperature influencer.

In accordance with an embodiment, a handheld intraoral scanner system is disclosed. A handheld intraoral scanner system includes a handheld intraoral scanner and a removable sleeve configured to be removably attached to a scanning tip of the handheld intraoral scanner. The removable sleeve includes a cover member and a window member. The window member includes a tapered portion. The window component may be injection molded. The removable sleeve may be formed by injection molding a dual assembly of a cover member and a window member. The window member includes an optical region having a lower birefringence than an unloading region located at the tapered portion, and includes an injection site at which a first molten polymer material is injected into the first core to form the window member. In accordance with an embodiment, there is provided a method for injection molding a window component for a removable sleeve, the removable sleeve further comprising a cover component and configured to be removably attached to a handheld intraoral scanner. The method may further include injection molding the lid member and the window member bi-assembly together to form a removable sleeve.

The application provides a fast-acting flunixin meglumine injection and a preparation method thereof, and belongs to the technical field of veterinary medicine, and contains the following components: flunixin meglumine 5-10 (w / v) %, alpha-pyrrolidone 10-30 (w / v) %, hydrophilic solvent 0.5-1 (w / v) %, antioxidant 0.1-0.3 (w / v) % and the balance of water for injection. The application takes flunixin meglumine as the main drug, matches alpha-pyrrolidone as a solvent and a targeting guide distribution component, uses a hydrophilic solvent to assist dissolution and promote absorption, and uses an antioxidant to inhibit the oxidative degradation of the main drug, so that the dissolution and absorption rate of the main drug and the target tissue distribution efficiency can be effectively improved, the storage stability can be ensured, the bacterial endotoxin and the injection site redness rate meet the requirements, the acute inflammation and pain of livestock and poultry can be quickly and efficiently relieved, and the demand for instant intervention in large-scale breeding can be met.

The invention relates to an ultrasonic guided injection site segmentation method and system based on artificial intelligence, and belongs to the technical field of image processing. The method comprises the following steps: acquiring an ultrasonic guided injection site image, and marking a segmentation mask in the image; the annotated image is preprocessed; constructing an ultrasonic guided injection site segmentation model, wherein the model comprises a coarse segmentation module and a fine segmentation module; the coarse segmentation module adopts a U-Net network architecture, and the fine segmentation module comprises an edge refining unit and a second feature fusion unit; inputting the preprocessed image into an ultrasonic guided injection site segmentation model for training; optimizing the model by using the loss function in the training process to obtain a trained model; and inputting a to-be-detected ultrasound-guided injection site image into the trained model to obtain an ultrasound-guided injection site segmentation result. According to the invention, the robustness of the ultrasound-guided injection site segmentation model can be enhanced, and the accuracy of ultrasound-guided injection site segmentation is improved.

Disclosed herein are system and method embodiments for fluoroscopic image based analysis of in-vivo fluid injections. For example, the method includes: obtaining a fluoroscopic image of an injection site, the fluoroscopic image including a matrix including a plurality of elements, and each element of the matrix including an intensity value; processing the fluoroscopic image to generate a prediction score for each element including a prediction of whether that element includes a fluid delivery depot location; providing a total area of the fluid delivery depot location, the total area of the fluid delivery depot location being determined based on the prediction score for each element of the plurality of elements; generating, based on the total area, at least one predicted parameter associated with the injection; and providing the at least one predicted parameter associated with the injection as a delivery characteristic.

A device for drug delivery includes a casing for housing a drug storage container including a dose delivery member. At least a portion of the dose delivery member extends through an opening in the casing. A guard is movable relative to the casing between an extended position and a retracted position. An interference arrangement provides a selected threshold of resistance to movement of the guard from the extended position to the retracted position during insertion of the dose delivery member into body tissue at an injection site. The interference arrangement has a first member and a second member engaging one another to retain the guard in the extended position. One of the first member and the second member moving if the selected threshold of resistance is exceeded to allow the first member and second member to slide past one another to allow the guard to move into the retracted position.

An automatic injection device is disclosed. The syringe includes a barrel for containing the fluid, a needle arranged at a proximal end of the barrel, and a movable plunger rod movable within the barrel. The automatic injection device includes a syringe retaining assembly for retaining the syringe; and a syringe driving assembly including a housing and a driving mechanism releasably arranged in the housing. The driving mechanism includes a movable body moveable after the driving mechanism is released, a first driving spring and a second driving spring, wherein the second driving spring is configured to drive the barrel of the syringe to move proximally to insert the needle of the syringe into an injection site of a target, and the first driving spring is configured to drive the movable plunger rod to move proximally to carry out injection; and the first and second driving springs have different spring stiffnesses.

The utility model belongs to the technical field of flue gas purification, and relates to a device for improving calcium-based dry desulfurization efficiency by dynamically jetting nanofluid, which comprises a nanofluid supply facility, a nanofluid ejector and a control system, the nanofluid supply facility comprises a nanofluid generator, a nanofluid conveying switch valve, a fluid pump, a nanofluid spraying time control electromagnetic valve, a nanofluid spraying flow control regulating valve and a nanofluid spraying site switch valve which are sequentially connected in the flowing direction of nanofluid. An outlet of the nanofluid injection site switch valve is connected with the nanofluid injector; the nano-fluid generator, the nano-fluid conveying switch valve, the nano-fluid spraying time control electromagnetic valve, the nano-fluid spraying flow control regulating valve and the nano-fluid spraying site switch valve are all connected with a control system; the nano-fluid ejector is arranged in a flue gas pipeline, is a multi-fluid ejector and is at least provided with more than two groups of forward-spraying / reverse-spraying injection heads.

The invention relates to a control device (10) for open-loop and / or closed-loop control of an injection pressure of a fluid and of an intraocular pressure when injecting the fluid at an injection site between two tissue layers of the human eye (1). The control device (10) contains an open-loop or closed-loop control unit which is designed for open-loop or closed-loop control of the injection pressure and the intraocular pressure in such a way that the gradient between the injection pressure and the intraocular pressure assumes a predetermined value.

A refrigerator appliance includes a cabinet defining an insulation receiving space between an outer casing and an inner liner, a dividing wall positioned within the insulation receiving space to divide the insulation receiving space into a first portion and a second portion, a first injection site for a first foam, and a second injection site for a second foam. The dividing wall includes one or more apertures therethrough.

The present application relates to a kind of micro-nano bubble liquid targeting injection system suitable for contaminated groundwater in-situ remediation, injection subsystem is prepared with micro-nano bubble liquid preparation mechanism Micro-nano bubble liquid, micro-nano bubble liquid is injected into injection well, with targeting injection device Micro-nano bubble liquid is targeted to injection into injection well, injection site adjusting mechanism Micro-nano bubble liquid is targeted to injection into injection site;Extraction subsystem includes extraction well.The present application is directly acted on specified injection site with micro-nano bubble liquid, effectively constructs underground oxidation environment, promotes microbial action, the energy generated by the breakage of micro-nano bubble promotes the generation of hydroxyl radical in groundwater, oxidizes and degrades pollutants, and the toxicity of byproduct is low, clean and green;Promote the effective contact of micro-nano bubble liquid and pollutants and its mass transfer in formation, improve the action efficiency of micro-nano bubble liquid;Overcome the shortcoming that different depth soil layer character is not the same, save engineering cost;Real-time monitoring is injection control feedback information.

The present disclosure provides a lipid compound, a lipid nanoparticle comprising the same and use thereof in the preparation of a drug delivery carrier. The lipid nanoparticle of the present disclosure can deliver a therapeutic or prophylactic agent (particularly a nucleic acid substance) to an injection site by intramuscular injection, and the therapeutic or prophylactic agent has high expression at the injection site but low expression in the viscera, which enables a drug to not only exert high activity but also have low visceral toxicity, and is of great significance to development and application of nucleic acid therapeutic or prophylactic agents.

A fluid migration method called invasion percolation (IP) is adopted for the carbon capture and storage (CCS) screening phase to predict the extent and location of CO2 plumes in the subsurface during and after injection. Results are compared to traditional reservoir models revealing similar outputs given the overall geological uncertainty. It can be concluded that IP as part of basin modeling is a fit for purpose method, which can assess multiple opportunities rapidly during the early intake screening phase of CCS sites. In addition to the plume evaluation, basin models can provide useful basin-scale or injection site specific pressure and temperature predictions as well as CO2 density estimates for static volume calculations before detailed reservoir and stratigraphic models are available. Hence, IP can be deployed successfully during the screening phase to assess risk and rank opportunities relative to each other and to build a CCS injection site portfolio.

The application belongs to the technical field of epidemic prevention auxiliary equipment for livestock, and discloses a vaccine injection auxiliary fence for livestock breeding, which comprises a fence body, a fixed box is fixedly installed at the bottom of one side of the fence body, a fixing mechanism is arranged in the fixed box, and the fixing mechanism comprises a transmission gear. The surface of the limiting strip is in contact with the head of the livestock, so that the livestock can be fixed, the limiting strip is relatively moved through the driving of the double-acting cylinder, the head of the livestock is fixed, the operator can more accurately find the injection site, injection deviation caused by the livestock moving around is avoided, injection risk is reduced, work efficiency is improved, the limiting strip is made of silica gel, and deformation occurs when the limiting strip is in contact with the head of the livestock, so that the discomfort of the fixed head of the livestock is reduced, and the risk of the livestock moving around is reduced.

A kind of intelligent insulin pen system with full-process and key operation voice prompt function, including insulin pen main body, pen cap is equipped on insulin pen main body, piston rod is equipped on the left end of insulin pen main body, liquid injection hole is opened in piston rod, connector is connected to the left end of piston rod, push motor is equipped on the left end of insulin pen main body, piston rod is drivingly connected with push motor, power module, microprocessor, vibration motor and temperature sensor are also equipped in insulin pen main body, injection button is equipped on the right end of insulin pen main body, display is equipped on insulin pen main body;After selecting smart device mobile phone and successfully connecting insulin pen system with smart device, open relevant interface, the relevant information of insulin pen system can be displayed, including insulin pen positioning, temperature, insulin pen cartridge installation time, residual quantity, injection frequency, recent three injection conditions, injection site atlas is displayed.The present application has simple structure and is convenient to use.

Provided is a system, method, and computer program product for determining a needle injection site. The method includes segmenting, with at least one computing device, an image of a sequence of images into at least one object based on a machine-learning model configured to estimate its uncertainty for each segmentation, generating, with the at least one computing device, a 3D model of the at least one object, and determining, with the at least one computing device, an insertion location of the at least one object based at least partially on an output of the machine-learning model.

A fluid handling system, method, and computer-readable storage medium are presented for controlling the flow and injection pressure of fluid injected into a subterranean void at an offshore injection site for long term storage. A subsea template receives fluid from a fluid storage arranged on a seabed in connection with at least two well heads for at least two drill holes to the void. For each drill hole, a first pressure gauge at the bottom opening of the drill hole measures a bottom pressure, PB. The template comprises a utility system causing received fluid to be injected into the void and includes a valve system with a choke valve for each drill hole to control the injection of fluid into the void in response to control commands (Ccmd) based on a pre-set desired flow rate for each drill hole and a pre-set lowest allowable flow rate from the fluid storage.

The invention discloses a design method for in-situ precise injection repair of a polluted site. The method comprises the following steps: step 1, investigating basic information of the site; 2, performing high-precision site investigation; step 3, partitioning the polluted site; step 4, setting and calculating partition injection parameters; 5, checking and optimizing partition injection parameters; step 6, performing partition accurate injection repair construction; and 7, repairing effect monitoring and optimization adjustment are carried out. According to the method, the polluted site is partitioned in the transverse direction and the longitudinal direction, and parameters such as the injection volume, the injection site number, the medicament preparation mass concentration and the like are determined in combination with high-precision investigation, so that accurate description of site characteristics in the partitions and accurate design of in-situ injection remediation of the polluted area can be realized; and meanwhile, by fusing the Internet of Things, artificial intelligence and a novel material technology, a sensing-decision-execution-verification closed-loop remediation system is constructed, and the method is suitable for soil and underground water remediation in various scenes such as organic pollution and heavy metal pollution.