13 results about "Invasive Procedure" patented technology

The utility model relates to a culture dish, in particular to a culture dish for a laser confocal microscope, which comprises a dish body and a cover body, the dish body is a cylinder with a shooting groove in the top surface; the cover body comprises an outer cylinder and an inner cylinder; the inner column body is arranged in the outer column body, and the top surface of the inner column body is not lower than the top surface of the outer column body; the outer column body is provided with an annular groove surrounding the inner column body, and the inner column body is provided with a culture groove; the cover body is detachably connected with the dish body; and when the cover body covers the opening in the top surface of the dish body, the culture groove and the shooting groove are oppositely arranged. Compared with the prior art, the culture dish for the laser confocal microscope solves the problems that a conventional culture dish in the prior art does not meet the requirements of the laser confocal microscope, and an existing culture dish for the laser confocal microscope is complex to use and tedious to operate. According to the scheme, the culture dish for the laser confocal microscope, which can be repeatedly used, has relatively small limitation on samples and can be directly used for experiments such as invasion and the like, is realized.

This invention relates to a method for diagnosing keratoconus by analyzing the geometric properties of Purkinje images. The method involves capturing Purkinje images of the cornea using a low-cost and simple device, such as a smartphone attachment, making it more accessible than current diagnostic tools like slit lamps. By comparing these images to reference images from healthy corneas, significant shifts and distortions are identified as indicators of keratoconus. This non-invasive tool provides an accessible and cost-effective means for early detection and ongoing monitoring. The method's reliability is ensured through extensive data collection from both healthy and keratoconic corneas. This approach offers primary assessments, especially in areas lacking access to advanced medical care, potentially reducing the need for more invasive procedures.

Systems and methods are provided for guiding a minimally-invasive procedure. A system includes an imaging system that provides an image of a region of interest and instructions are executable by the processor to provide a tracking sensor interface that receives a position of a first medical device within the region of interest. An overlay generator generates a model of one or both of the first medical device and a second medical device, having a known position and orientation relative to the first medical device, based on the position of the first medical device and a state associated with the device. An image merger registers the overlay to the image and combines the overlay with the image to generate the augmented representation of the region of interest. A display provides the augmented representation of the region of interest to a user in real-time.

Exemplified methods and systems facilitate presentation of data derived from measurements of the heart in a non-invasive procedure (e.g., via phase space tomography analysis). In particular, the exemplified methods and systems facilitate presentation of such measurements in a graphical user interface, or “GUI” (e.g., associated with a healthcare provider web portal to be used by physicians, researchers, or patients, and etc.) and / or in a report for diagnosis of heart pathologies and disease. The presentation facilitates a unified and intuitive visualization that includes three-dimensional visualizations and two-dimensional visualizations that are concurrently presented within a single interactive interface and / or report.

A process for analysing chromosome interactions relating to colorectal cancer. The invention allows determination of the colorectal cancer status using a systemic blood-based profile of a chromosome conformation signature (3D genomic) state. This avoids the need to use invasive procedures. In particular, the invention allows blood-based detection of colorectal cancer status and distinguishing between groups of individuals who differ in their colorectal cancer status. This also results in a test of high sensitivity and specificity.

This invention provides a dual-wavelength confocal superlens and its design method, as well as a photoacoustic imaging method and system, belonging to the field of optical lens technology. The invention provides a design method for a dual-wavelength confocal superlens that can use two different wavelengths of light to visualize cancer cells and normal tissues. Normal cells and cancer cells absorb energy from the two different wavelengths, causing them to heat up and expand. After cooling, they emit ultrasonic waves, which are then collected by an ultrasonic transducer. Finally, photoacoustic imaging is achieved through calculation. This invention aims to enhance photoacoustic imaging contrast while avoiding the risks of invasive procedures. The dual-wavelength design provides multiple contrast mechanisms, allowing for the comparison of various tissue features during the same imaging process, enhancing the detection capability of lesions, and effectively reducing the influence of noise in the photoacoustic signal. This invention can be applied to early cancer detection and can also be used to monitor tumor response during treatment and evaluate treatment effectiveness.

This invention discloses a topical patch that can relieve bone spur pain and partially or completely eliminate bone spurs, belonging to the field of topical medical dressing technology. This patch can quickly relieve pain and inflammation symptoms caused by bone spurs, and can specifically target the abnormally proliferating material of the bone spur, achieving the effect of partially or completely eliminating the bone spur. The effective time is 3-5 hours, and the efficacy is maintained for up to 12 hours. The application method is flexible, and the usage plan can be adjusted according to skin condition and bone spur status. No surgery, injections, or other invasive procedures are required, avoiding the limitations of traditional bone spur treatment methods. It is convenient to use, highly safe, and suitable for relieving and treating bone spurs of different locations and sizes. The topical patch of this invention has a reasonable structural design, scientific component ratio, no additional additives, high transdermal absorption efficiency, and significant therapeutic effect on bone spurs, possessing good clinical application and promotional value.

Herein is provided a method of reversing ticagrelor-enhanced bleeding in a patient comprising administering to said patient during surgery, in a perioperative setting, or during an invasive procedure an antibody or antigen-binding fragment thereof that binds to ticagrelor. Also provided is a method of reversing ticagrelor-enhanced bleeding in a patient comprising administering an antibody or antigen-binding fragment thereof that binds to ticagrelor, wherein the patient is elderly, has underlying cardiac or pulmonary or metabolic disease, optionally wherein the patient has a minimum percent inhibition of P2Y 12 reaction units (PRU) over 4 hours after starting administration of the antibody or antigen-binding fragment thereof that is less than the percent inhibition of PRU before administration.

Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a monopolar knife assembly attached to the distal end of the shaft, the monopolar knife assembly comprising a knife; a handle attached to the proximal end of the shaft; wherein the shaft comprises a flexible portion and an articulating portion, wherein the flexible portion extends distally from the handle and the articulating portion extends distally from the flexible portion; wherein at least one articulation cable extends from the handle to the articulating portion, such that when tension is applied to the at least one articulation cable, the articulating portion deflects; wherein an actuation element extends through the shaft from the handle to the knife, such that when the actuation element is moved, the knife is moved; and wherein the actuation element transmits electrical power from the handle to the knife.

A percutaneous minimally-invasive procedure to prevent a potential fracture in an osteoporotic vertebra of an osteoporotic patient is provided by minimally-invasively delivering a biocompatible and resorbable porous calcium-based granular material into the osteoporotic vertebral body.

Herein is provided a method of reversing ticagrelor-enhanced bleeding in a patient comprising administering to said patient during surgery, in a perioperative setting, or during an invasive procedure an antibody or antigen-binding fragment thereof that binds to ticagrelor. Also provided is a method of reversing ticagrelor-enhanced bleeding in a patient comprising administering an antibody or antigen-binding fragment thereof that binds to ticagrelor, wherein the patient is elderly, has underlying cardiac or pulmonary or metabolic disease, optionally wherein the patient has a minimum percent inhibition of P2Y12 reaction units (PRU) over 4 hours after starting administration of the antibody or antigen-binding fragment thereof that is less than the percent inhibition of PRU before administration.

A percutaneous minimally-invasive procedure to prevent a potential fracture in an osteoporotic vertebra of an osteoporotic patient is provided by minimally-invasively injecting a non-dispersive, biocompatible and resorbable calcium-based cement paste into the osteoporotic vertebral body.

Provided is a basivertebral nerve ablation apparatus, which comprises a cannula assembly (20) and an ablation assembly (30). The cannula assembly (20) comprises a filling tube (21) and a retraction component, a lining core (211) is provided inside the filling tube (21), and the retraction component is connected to the filling tube (21) so as to at least be used for driving the filling tube (21) to move relative to the lining core (211) in the length direction of the filling tube (21). The ablation assembly (30) comprises an ablation electrode (31) and an electrode handle (32), and the ablation electrode (31) is fixedly connected to the electrode handle (32). When the ablation electrode (31) is operated, the ablation electrode (31) is sleeved inside the filling tube (21). The ablation apparatus solves the problems of poor outcomes of long-term conservative treatment of chronic low back pain and its susceptibility to recurrence, as well as the tendency to cause lumbar stiffness and limited mobility in patients when chronic low back pain is treated with invasive procedures and other methods.