96 results about "Inferior vena cava" patented technology

Tricuspid valve repair devices and associated systems and methods are disclosed herein. A tricuspid valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the tricuspid valve to at least partially fill a space between the native leaflets. The tricuspid valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. The fixation mechanisms can include clip mechanisms, lock mechanisms, stabilization members, anchors, and / or other structures configured to engage cardiac anatomy local to or remote from the tricuspid valve, such as the native leaflets, the tricuspid valve annulus, the right ventricular outflow tract, the superior vena cava, the inferior vena cava, and so on.

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

The invention relates to the technical field of medical treatment, and discloses an intraperitoneal hepatic vein blood flow blocking device which comprises a drainage tension-brace mechanism, a hepatic vein blocking mechanism is arranged on the surface of the drainage tension-brace mechanism, a catheter recycling mechanism is arranged on the surface of the hepatic vein blocking mechanism, a hydraulic measuring mechanism is arranged at one end of the catheter recycling mechanism, and the hydraulic measuring mechanism is connected with the drainage tension-brace mechanism. And a normal saline injection mechanism is arranged at one end of the hydraulic measuring mechanism. According to the intraperitoneal hepatic vein blood flow blocking device, through the arrangement of the drainage pulling and supporting mechanism, the hepatic vein blocking mechanism, the catheter recycling mechanism, the hydraulic measuring mechanism and the normal saline pushing and injecting mechanism, the hepatic vein can be directly blocked through expansion of the hepatic vein blocking mechanism in the using process, and meanwhile it is guaranteed that the inferior vena cava blood flow can flow through a circulation cavity; therefore, smooth return blood circulation of the inferior vena cava is guaranteed.

A method, for use at a mitral valve of a heart of a subject, is provided which includes advancing a transluminal sheath into a femoral vein of the subject, through an inferior vena cava of the subject, into a right atrium of the subject, and transseptally into a left atrium of the subject. A surrounding-sheath is advanced out of a distal end of the transluminal sheath, into the left atrium, and toward a commissure of the mitral valve. An anchor is implanted by advancing the anchor out of the surrounding-sheath into a left ventricle of the subject, such that the anchor helically wraps around left ventricular mitral valve tissue. The surrounding-sheath is then extracted from the heart and then, a guide wire is advanced through the transluminal sheath. Other embodiments are also described.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

The invention relates to a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

An intravascular ultrasound “(IVUS”) device having an intrinsic or attachable needle guide is disclosed. In some embodiments, a sheath having a needle guide is used in connection with an IVUS device. The devices may be used in performing minimally invasive image-guided surgical procedures. The devices may be configured to maintain a needle placed through guide in the plane of the IVUS-array to improve visualization of the needle. In some embodiments, the device is used to facilitate the creation of a tract through the liver from the inferior vena cava to the portal vein using IVUS-guidance in a direct intrahepatic portocaval shunt procedure. The devices, systems, and methods can improve patient safety by decreasing the risk of off-target punctures, decrease procedure times, and allow procedures to be performed from a single access site.

A method and system for performing transseptal extracorporeal membrane oxygenation is disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. A first portion of the catheter system can remove blood from the patient, in some examples near the inferior vena cava. A second portion can return oxygenated blood to the patient, through the transseptal puncture and into the aorta.

The invention relates to the technical field of clinical decision support and medical data intelligent analysis, in particular to a critical patient individualized liquid resuscitation decision support system, which is characterized in that a data acquisition unit acquires pulse pressure variation waveform and multi-dimensional physiological data of each stroke volume; a volume benefit analysis channel of the dynamic decision-making unit segments a respiratory cycle, extracts pulse pressure fluctuation characteristics, outputs a per-stroke volume increase probability value through a machine learning classifier, an organ injury early warning channel calculates a blood lactic acid and creatinine clearance rate change rate, and generates an acute kidney injury risk sign in combination with inferior vena cava image verification; the execution control unit sends an infusion control or limit instruction according to the combined state; and the feedback optimization unit adjusts the weight of the model according to the actual value of blood lactic acid removal, and recalculates the probability value, so that individualized precise resuscitation, balance capacity benefit and organ protection are realized, and the treatment safety and effectiveness are improved.

Medical delivery system for accessing a tricuspid valve via an inferior vena cava, including an outer guide catheter, an inner guide catheter and an interventional catheter. The first deflection portion of the outer guide catheter is steerable to define a first outer-guide-catheter curve and the second deflection portion of the outer guide catheter is steerable to define a second outer-guide-catheter curve and the first deflection portion of the inner guide catheter is steerable to define a first inner-guide-catheter curve.

The present application relates to cell preparation process in the field of bioengineering, disclose a kind of high-efficiency preparation mouse primary hepatocyte method, comprising: perfusion needle is placed in reverse direction to liver direction through inferior vena cava, utilize the blood vessel clamp with elastic micro-tooth damping surface to lock the perfusion needle and inferior vena cava wall;The overflow damping of hepatic portal vein outflow end is dynamically regulated by blood vessel clamp, to construct controlled positive pressure permeation environment in liver vascular bed;Collagenase solution is radially permeated to liver parenchyma using the environment, the present application makes enzyme solution radial deflection and cross blood sinus barrier into di's cavity by constructing micro-pressure environment, eliminate the digestion dead zone originally due to flow path preference, ensure that enzyme molecule and extracellular matrix are uniformly contacted in global dimension, realize the collaborative promotion of tissue cutting efficiency and total amount of cell release, ensure that the output cell population has highly consistent physiological state.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valves are implanted using catheter-based deployment systems that include multiple control wires. In particular implementations, the deployment systems can include a retrieval catheter that can be used to recapture the prosthetic heart valve back into a delivery sheath after being expressed from the delivery sheath. The prosthetic heart valves can include a plurality of optional suture knots to enhance migration resistance. Some delivery catheter systems can include a controllably bendable control catheter and / or a deflectable catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

A volume management apparatus includes a cardiac evaluation unit configured to evaluate whether the patient suffers from an organic heart disease based on an image of apical four chamber view; a parameter determination unit configured to determine a maximum inner diameter of inferior vena cava and a collapse rate of inferior vena cava based on an image of subxiphoid inferior vena cava view; a score calculation unit configured to determine scores that correspond to the LVEF value, the maximum diameter of the inferior vena cava, and the collapse rate of the inferior vena cava, respectively; and a fluid management plan determination unit configured to search for a fluid management plan corresponding to a score determined, and to perform volume management for the patient according to the fluid management plan searched.

The invention relates to constriction devices and methods for deploying a laterally delivered prosthetic heart valve in a native annulus. The present invention relates to anchoring channels and subannulus anchors for transcatheter heart valve replacement (A61F2 / 2412), and in particular for transcatheter prosthetic heart valves with orthogonal delivery of an annulus support frame having a compressible wire unit, the compressible wire unit facilitates rolling and folding of the valve in a longitudinal direction or orthogonal to a central axis of the flow control member, allowing delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve, or trans-atrial delivery and deployment to the mitral valve, or delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve. The valve has a height of about 5 mm to 60 mm and a diameter of about 25 mm to 80 mm without the need for an over-diameter catheter and without the need for delivery and deployment from the catheter at an acute access angle.

The present invention relates to an anchoring channel and a subannular anchor for transcatheter heart valve replacement (A61F2 / 2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having an annular support frame having a compressible wire unit that facilitates rolling and folding of the valve longitudinally or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or delivered and deployed transatrially to the mitral valve, the valve having a height of approximately 5 mm-60 mm and a diameter of approximately 25 mm-80 mm, without the need for an overly large diameter catheter and without the need for delivery and deployment from the catheter at an acute approach angle.

The application discloses an ultrasonic imaging system for accurately collecting heart sections in any body position, which comprises a plurality of two-dimensional ultrasonic arrays randomly distributed in space, a multichannel ultrasonic signal collecting module and a three-dimensional ultrasonic imaging module; the plurality of two-dimensional ultrasonic arrays, the multichannel ultrasonic signal collecting module and the three-dimensional ultrasonic imaging module are sequentially connected; wherein the plurality of two-dimensional ultrasonic arrays comprises a plurality of ultrasonic transducer arrays forming sub-area line scanning or sub-area surface scanning or cross surface scanning; the application provides doctors with more detailed images, which is helpful for more accurately positioning and evaluating lesions; can solve the problems of difficulty in collecting correct imaging sections, imaging section changes in motion and the like in wearable ultrasonic heart imaging; is not only suitable for the heart, but also suitable for the brain, the liver, the kidney, the urinary bladder, the abdominal aorta, the inferior vena cava and the like human tissues and parts.

Medical delivery system for accessing a tricuspid valve via an inferior vena cava, including an outer guide catheter, an inner guide catheter and an interventional catheter. The first deflection portion of the outer guide catheter is steerable to define a first outer- guide-catheter curve and the second deflection portion of the outer guide catheter is steerable to define a second outer-guide-catheter curve and the first deflection portion of the inner guide catheter is steerable to define a first inner-guide-catheter curve.

The invention belongs to the technical field of in-vitro organ perfusion, and provides a sequential liver perfusion machine integrating acquisition, storage and transplantation. The device comprises an organ containing module which is provided with an organ containing basin; the in-vitro organ perfusion module is used for establishing perfusate circulation for the in-vitro organs placed in the organ accommodating basin; the in-vitro lung simulation module is used for inputting gas components into perfusate; the temperature adjusting module is used for adjusting the temperature of the perfusate; a perfusate exchange module; and the NRP module is used for injecting blood into the abdominal aorta of the donor and collecting blood flowing out of the inferior vena cava. Compared with the prior art, a clinical transplantation scheme is improved; a UW-MP, oxygen-containing carrier colloidal fluid and blood continuous exchange scheme is provided, and the organ quality is effectively improved; the convenience of preparation and use of the machine is improved, and the cost of consumables is reduced; the blood vessel tension change can be continuously and quickly coped with; in conclusion, the safety and stability of the perfusion system are obviously improved, and the mental pressure of medical staff is reduced.

A method for performing a robotic-assisted orthotopic heart transplant includes forming a working port subareolarly by a mini-thoracotomy at a working intercostal space, forming additional ports for robotic arms, and arranging robotic arms through the ports. A first robotic arm with first forceps extends through a second port lateral to a mid-clavicular line, while second and third robotic arms containing an imaging device and second forceps operate through the working port. A fourth robotic arm with scissors or needle holder extends through a third port proximal to an anterior axillary line. The method includes cannulating for cardiopulmonary bypass, opening the pericardium, cross-clamping the aorta, removing the native heart, and performing sequential anastomoses of the donor heart including the left atrium, pulmonary artery, aorta, inferior vena cava, and superior vena cava.

The invention provides computer equipment for executing an inferior vena cava ultrasonic image real-time analysis and evaluation method in hemodialysis, the computer equipment comprises a memory, a processor and a computer program, when the processor executes the program, inferior vena cava ultrasonic image data in the hemodialysis process is obtained, the delay duration of inner diameter contraction response is recognized, and the delay duration is calculated; determining a latency plateau period duration based on a time period in which the inner diameter of the blood vessel is maintained relatively stable after the liquid removal speed is changed; according to the latency plateau period duration, when the blood vessel wall rebound speed is higher than the inner diameter contraction speed, high-elasticity reserve is recognized, and according to the inner diameter fluctuation range corresponding to the high-elasticity reserve, the blood volume safety range and the contraction speed threshold value are obtained; acquiring a blood volume measurement value at an ultrafiltration rate intervention time point, triggering reverse adjustment when the blood volume measurement value exceeds a blood volume safety range, and extracting a stable inner diameter contraction speed after the blood volume is stable.

The present disclosure provides a transcatheter device including: an anchor (200) anchored to an inner wall of an inferior vena cava (IVC); and a main shaft (10) having a proximal shaft (110) that extends from the anchor (200) toward a tricuspid valve (TV) along a cavotricuspid isthmus (CTI) of a heart, a middle shaft (120) that extends from the proximal shaft (110), passes through the TV, and has a spacer (300) preventing a reverse flow in the TV mounted thereon, and a distal shaft (130) that extends from the middle shaft (120) into a pulmonary artery (PA), and the distal shaft (130) of the main shaft (100) includes a first distal part (131) that extends in a curved shape having a predetermined curvature from the middle shaft (120), a second distal part (132) that extends from the first distal part (131) and bends at point B1, which is one point that is over and surrounds an aorta, toward the proximal shaft (110), and a third distal part (133) that extends from the second distal part (132) toward the proximal shaft (110).

The invention discloses a neonatal umbilical artery and vein puncture catheterization training model which is characterized by comprising a neonatal model and a puncture needle model. A simulated heart is arranged in the thoracic cavity of the newborn model; the aorta and the inferior vena cava are connected with the simulated heart; the puncture needle model is rod-shaped, and a working part is arranged at the front end of the puncture needle model; the periphery of the vein puncture path and the artery puncture path is sleeved with a plurality of sets of electromagnetic coils in the axial direction; each group of electromagnetic coils is provided with an independent main switch, and the main switches of all the electromagnetic coils are arranged along a puncture path one by one, so that the main switch can be triggered when the working part of the puncture needle model passes through one main switch, and the corresponding electromagnetic coil is electrified to generate an acting force in a correct puncture direction on the working part. According to the invention, force sense direction guidance can be provided during puncture practice.

The invention provides a mitral valve clip operation simulator which comprises a bottom plate, and a first side of the bottom plate is provided with a first storage groove and a second storage groove; the first module is provided with an atrial septum simulation part and a mitral valve simulation part, and the first module is arranged on the bottom plate in the mode that the first module can be switched between an unfolded state and a folded state; the second module is provided with a lower cavity tube used for simulating the inferior vena cava, and the second module is arranged on the bottom plate in a mode of being capable of being switched between an unfolded state and a folded state; when the first module is in an unfolded state, the atrial septum simulation part and the mitral valve simulation part protrude out of the bottom plate, and the positions of the atrial septum simulation part and the mitral valve simulation part form an analogue simulation position; when the second module is in an unfolded state, the lower cavity tube protrudes out of the bottom plate to form a surgical instrument access path; when the first module is in the folded state, the first module is integrally contained in the first containing groove, and when the second module is in the folded state, the second module is integrally contained in the second containing groove.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

This invention discloses a method for blood collection from the right adrenal vein, belonging to the field of venous blood collection methods. The method includes the following steps: providing an RH catheter, which is a dedicated catheter for hepatic artery angiography, with its tip bent 180° to form a plane, and its tip bent perpendicularly to this plane at 90°; inserting the RH catheter through the right femoral vein, advancing it to form a loop in the right atrium, and then pulling it back to the inferior vena cava; adjusting the direction of the RH catheter, using its three-dimensional curved portion to hook onto the opening of the right adrenal vein, thereby inserting it into the right adrenal vein; injecting contrast agent to confirm that the tip of the RH catheter is located within the right adrenal vein; collecting a blood sample from the right adrenal vein through the RH catheter, with a single blood sample volume of 12 ml; after blood collection, performing post-confirmation angiography to verify whether the RH catheter is located within the target vein. This invention can significantly improve the success rate of right-side catheter insertion and blood collection efficiency, while reducing costs and facilitating operation.

The circulation assist devices disclosed herein can be used, for example, in methods of decreasing venous pressure in the Fontan circulation. The devices can include an inlet, an outlet, a stator, a rotor, and an impeller driven by rotation of the rotor. In some embodiments, the impeller blade (or blades) can at least partially define a central lumen extending through the device. The device can be coupled to the inferior vena cava and the pulmonary artery. Rotating the impeller blade(s) increases blood velocity through the lumen and causes the outlet pressure to be higher than the inlet pressure. The impeller can be configured such that, when it is stationary, the forward static pressure drop between the inlet and the outlet is minimized. That is, the forward static pressure drop of the device approximates the pressure drop between the inferior vena cava and central pulmonary artery of the unassisted Fontan circulation.

The utility model discloses an invalid circulation prevention extracorporeal membrane oxygenation cannula which comprises a drainage tube body, and a blocking balloon assembly is arranged on the outer surface of the drainage tube body. The blocking balloon assembly comprises two blocking balloons, a connecting pipe is connected between the two blocking balloons, two communicating holes are formed in the connecting pipe and communicated with the two blocking balloons respectively, the safety of intubation is improved, meanwhile, it is effectively guaranteed that unoxygenated superior vena cava blood and unoxygenated inferior vena cava blood are drained to be oxygenated outside the body, and therefore the safety of intubation is improved. The function of preventing ineffective circulation through single-tube oxygenation is achieved, compared with traditional double-tube oxygenation, the situation that blood which is infused back just after oxygenation is repeatedly drained out of the body, and ineffective oxygenation is caused can be avoided, and the effectiveness of blood oxygenation is ensured.

The invention discloses an ultrasonic imaging method and an ultrasonic imaging system for a fetus in the middle-late pregnancy period. The method comprises the following steps: S220, obtaining three-dimensional ultrasonic data of the fetus in the middle-late pregnancy period; s230, according to the three-dimensional ultrasonic data, the long axis direction of the body area of the fetus in the middle-late pregnancy period is determined; s540, extracting information of a mid-late pregnancy target feature structure of the fetus from the three-dimensional ultrasonic data, wherein the mid-late pregnancy target feature structure comprises at least one of the following parts: gastric vesicle, spine bone, liver, umbilical vein, descending aorta, inferior vena cava, umbilical cord insertion position, umbilical cord, anterior abdominal wall, bladder, legs, umbilical artery and gallbladder; and S560, extracting at least one abdominal standard section of the fetus in the middle-late pregnancy period from the three-dimensional ultrasonic data according to the information of the long axis direction and the middle-late pregnancy target feature structure, and displaying the extracted abdominal standard section. According to the ultrasonic imaging method and the ultrasonic imaging system, the abdominal standard sections of the fetuses in the middle-late pregnancy period are automatically extracted according to the three-dimensional ultrasonic data collected at a time, a doctor does not need to manually extract the abdominal standard sections one by one, and the efficiency of extracting the abdominal standard sections and the quality of the extracted abdominal standard sections are improved.

The invention relates to a tricuspid regurgitation control device for an orthogonal transcatheter heart valve prosthesis. The invention also relates to access and occluder devices, in particular heart valve regurgitation drums and optionally closure discs and / or tubular stents, for managing and providing intentional regurgitation levels within transcatheter heart valve substitutes and in particular orthogonally delivered transcatheter prosthetic heart valves, an orthogonal delivery transcatheter prosthetic heart valve has a first inner flow control member / valve, a second inner reflux control member, and an outer annular support frame with a compressible wire unit that facilitates flat folding along the z-axis and compression of the valve vertically along the y-axis or orthogonal to the central axis of the flow control member, the present invention relates to a valvular delivery and deployment system, in particular to a valvular delivery and deployment system, which allows delivery and deployment of very large diameter valves from the inferior or superior vena cava to the tricuspid valve or trans-atrial delivery and deployment to the mitral valve, the valves having a height of about 5-60 mm and a diameter of about 25-80 mm, without extra-large diameter catheters and without delivery and deployment from catheters at acute access angles.