53 results about "Normal blood" patented technology

The invention provides a matrix type balloon dilatation catheter, and belongs to the technical field of balloon catheters. The balloon dilatation catheter comprises a catheter body and a balloon assembly, wherein a guide tip is arranged at the far end of the catheter body; the balloon assembly is arranged at the far end of the catheter body, the far end of the balloon assembly is adjacent to the near end of the guide tip, the balloon assembly is provided with a plurality of rows of balloon units arranged in the axial direction of the catheter body, each balloon unit is provided with a plurality of sub-balloon bodies arranged in the circumferential direction of the catheter body, and each sub-balloon body is used for being independently filled or contracted. The balloon assembly has a plurality of filling shapes; the technical problems that in the prior art, the overall filling shape of a balloon cannot be flexibly adjusted, normal blood vessels are prone to being damaged, and a patient feels uncomfortable obviously are mainly solved.

The invention provides a matrix type balloon dilatation system, and belongs to the technical field of balloon catheters. The system comprises a catheter, a balloon assembly, a filling medium storage part and a flow control part, the balloon assembly is arranged at the position, close to the far end by a set distance, of the catheter, the balloon assembly is provided with a plurality of rows of balloon units arranged in the axial direction of the catheter, and each balloon unit is provided with a plurality of sub-balloon bodies arranged in the circumferential direction of the catheter; each sub-balloon body is used for independently filling or scaling; the filling medium storage part is communicated with the near end of the catheter and is used for providing a filling medium for each sub-balloon body; the flow control part is communicated with the filling medium storage part and is used for controlling filling or scaling of each sub-balloon body according to the pressure in the balloon assembly; the technical problems that in the prior art, the overall filling shape of a balloon cannot be flexibly adjusted, normal blood vessels are prone to being damaged, and a patient feels uncomfortable obviously are mainly solved.

The application discloses a kind of thrombus suction control method and thrombus suction device, and thrombus suction device includes suction assembly, suction assembly includes the shell with pressure cavity, piston rod and suction catheter, thrombus suction device also includes the motor of piston rod movement and the controller connected with motor, control method is: suction catheter is positioned to the blood vessel without thrombus, make motor operate according to speed V0, calibrate the pressure value B in pressure cavity under normal blood condition;Suction catheter is positioned to the blood vessel with thrombus, make motor operate according to speed V1, V1≤V0, make dynamic pressure value A0 in pressure cavity: when A0≤B, make motor keep speed V1 operation;When A0>B, make motor increase from speed V1: when B<A0≤C, make motor increase to speed V2 operation;When C<A0≤D, make motor increase to speed V3 operation;When D<A0≤E, make motor increase to speed V4 operation.The control method thrombus removal efficiency is high, and blood loss can be reduced.

The invention relates to the technical field of underground safety monitoring and occupational health protection, and discloses an eye movement and multi-mode sensing underground protective glasses and an early warning method. And an elevation angle eye movement sensing module, an inertial sensor, a PPG and body temperature galvanic skin sensor, an acoustic component, a wireless communication module and a detachable glasses leg battery module are connected. The method comprises the steps that eye images and multi-source physiological data are collected in real time, and a multi-dimensional state judgment model is constructed; the logic contradiction between normal blood oxygen value and slow eye movement response is innovatively used for recognizing hidden carbon monoxide poisoning, accidental slipping and coma falling are distinguished through a posture and eye movement cooperation mechanism, and meanwhile the active noise reduction function is achieved. The problems that traditional equipment cannot recognize hidden poisoning and the falling false alarm rate is high are solved, and accurate sensing and early warning of physiological fatigue, poisoning symptoms and safety states of underground personnel are achieved.

According to the bleeding cage and the blood pump thereof, the blood mixing loss can be reduced, the supporting strength is good, the whole bleeding cage is in a circular tube shape, a far-end opening of the bleeding cage forms a blood inlet, a bleeding opening and a flushing outlet are formed in the outer wall of the bleeding cage, and the bleeding opening and the flushing outlet are formed in the axial direction at intervals. Normal blood pumped by the blood pump flows out from the blood outlet, and flushing fluid flows out from the flushing outlet after flushing the gap, so that energy loss caused by blood mixing is reduced, and the hydraulic performance of the blood pump is improved; the bleeding cage has a certain length in the axial direction, and the bleeding opening and the flushing outlet are arranged at an interval, so that the overall structural strength of the bleeding cage is ensured, and the bleeding cage is prevented from being deformed due to stress; meanwhile, the turbulence influence generated when blood flows through the bleeding cage is reduced, stable rotation of the magnet is improved, and then the rotation stability of the whole blood pump is guaranteed.

The utility model discloses a structure capable of realizing urgent detection of a single blood smear, which comprises a support table, wherein an X-axis linear moving module is arranged on the support table; the slide urgent cabin is connected to the X-axis linear moving module and is driven by the X-axis linear moving module to move along the X-axis direction; a jacking hole is formed in the bottom surface of the slide urgent cabin; a lifting plate is arranged on the supporting table and located below the slide urgent cabin, jacking supporting columns are arranged on the top face of the lifting plate, a lifting mechanism is arranged on the supporting table, and the driving end of the lifting mechanism is connected to the lifting plate to drive the lifting plate to ascend and descend in the direction close to or away from the slide urgent cabin. The slide conveying table is close to or far away from the upper surface of the slide urgent cabin in the Y-axis direction. According to the utility model, the automatic urgent detection of a single blood smear can be realized without manually stopping or waiting for the scanning work of a normal blood smear by medical staff, so that the working intensity of the medical staff is reduced while the working efficiency is improved.

The utility model relates to the technical field of vein blood sampling, in particular to an anti-backflow vein blood sampling device. The utility model provides an anti-backflow vein blood sampling device which can effectively prevent blood from flowing back and ensure normal blood sampling work. An anti-backflow vein blood sampling device comprises a needle head, a connecting piece, a needle wing, a connecting pipe, a fixing assembly and the like, the connecting piece is connected to the left portion of the needle head, the needle wing is connected to the upper side of the right portion of the connecting piece, the connecting pipe is connected to the left side of the connecting piece, and the fixing assembly capable of being fixed to an arm is arranged on the connecting piece. After blood flows into the control cylinder, the blood flows into the conical thin film and the hard tube, the conical thin film and the hard tube are kept in linear communication and then flow out of the collecting head, and after the blood stops flowing into the conical thin film, the hard tube droops under the action of gravity to block the conical thin film, so that the blood can be effectively prevented from flowing back; and the effect of normal blood sampling work is ensured.

The invention relates to the technical field of medicines, and discloses an application of a traditional Chinese medicine composition in serum neurotransmitter, which comprises the following steps: selecting 6-8 weeks old mice to establish a normal model, a chronic fatigue syndrome model and a functional dyspepsia model; the method comprises the following steps: sampling blood from mice of a normal model, a chronic fatigue syndrome model and a functional dyspepsia model to respectively obtain a normal blood sample, a CFS blood sample and an FD blood sample, and performing protein precipitation operation to obtain normal deproteinized supernatant, CFS deproteinized supernatant and FD deproteinized supernatant; separating by using a reversed-phase chromatographic column, and then carrying out mass spectrometric detection to respectively obtain a normal serum neurotransmitter mass spectrogram, a CFS serum neurotransmitter mass spectrogram and an FD serum neurotransmitter mass spectrogram; and carrying out concentration value calculation and rhythm fluctuation analysis to respectively obtain a neurotransmitter function index and a rhythm stability quantitative score. Therefore, the action mechanism of the serum neurotransmitter of the traditional Chinese medicine composition can be clearly and quantitatively represented.

The present invention discloses a communication device for bridging vascular injuries, comprising a bridging tube, with connecting portions provided at both ends of the bridging tube, the connecting portions being provided between the blood vessel and the bridging tube; a branch tube being provided on the outer periphery of the bridging tube to provide a channel for blood vessel supply, the branch tube being provided perpendicular to the axis of the bridging tube; the connecting portion comprising a straight section and a tapered section, both of which are integrally formed; a connecting thread being provided on the outer periphery of the straight section, a connecting thread being provided on the inner sidewall of the end of the bridging tube, the straight section of the connecting portion being threadedly connected to the bridging tube; and the tapered section of the connecting portion being inserted into the blood vessel and fixed by adhesive. The communication device for bridging vascular injuries provided by the present invention has a reasonable structure and is easy to connect, effectively ensuring normal blood supply and avoiding limb ischemia, necrosis, and disability caused by insufficient blood supply.

Provided is a method for selecting a blood specimen having a possibility of including a coagulation abnormality, the method including: acquiring a parameter Ps(X) based on a coagulation reaction curve Rs(i) or a primary differential curve Vs(i) thereof for a test blood specimen, where the test blood specimen is a blood specimen for which it has not been possible to decisively determine the presence of prolonged APTT, i is a measurement point or time, and X is a variable and is greater than 0; acquiring a parameter Pm(X) for a normal blood specimen; and acquiring an index S for the test blood specimen on the basis of formula (2), (2)', or (2)", where Fs(X) = Ps(X) − Ps(c) and Fm(X) = Pm(X) − Pm(c), or Fs(X) = Ps(X) / Ps(c) and Fm(X) = Pm(X) / Pm(c), a > 0 and a ≤ b, 0 < c ≤ M, and M is a maximum value of X.

The invention relates to the technical field of hemostatic materials, and provides chitosan-based in-situ self-gel powder as well as a preparation method and application thereof. The chitosan-based in-situ self-gel powder provided by the invention comprises modified chitosan-based powder and oxidized polysaccharide powder, the modified chitosan-based powder is prepared from poly (3-sulfopropyl methacrylate potassium salt) grafted chitosan and poly [2-(methylacryloyloxy)-ethyltrimethyl ammonium chloride] grafted chitosan. The chitosan-based in-situ self-gelling powder provided by the invention has an in-situ self-gelling function, can quickly absorb water to realize self-gelling under the triggering of body fluid or blood, has excellent wet tissue adhesion performance, is high in water absorption speed and good in hemostatic effect, is not influenced by a normal blood coagulation mechanism in a hemostatic process, and has good postoperative anti-adhesion performance; no chemical cross-linking agent is used in the preparation process of the chitosan-based in-situ self-gel powder, the chitosan-based in-situ self-gel powder has good biocompatibility and biodegradability, raw materials are easy to obtain, synthesis is simple, and the chitosan-based in-situ self-gel powder is economical and safe.

Provided are a branch artery reconstruction assist device and an SC branch-preferential aortic reconstruction system, the branch artery reconstruction assist device comprising a first stent body (20a), the first stent body (20a) comprising a bare stent portion (23a), and a cardiac proximal covered stent portion (21a) and a cardiac distal covered stent portion (22a) connected to both sides of the bare stent portion (23a), and a sealing membrane (219a, 229a) and at least one sealing membrane (229a) are provided inside both the cardiac proximal covered stent portion (21a) and the cardiac distal covered stent portion (22a). Two coated stents (211a, 212a, 221a) are provided, and the sealing membranes (219a, 229a) include first openings (213, 214, 222), which are connected to corresponding first ends of the coated stents (211a, 212a, 221a), and the second ends of the coated stents (211a, 212a, 221a) are connected to corresponding branch artery coated stents (216, 217, 218) to form branch channels, and pass through the bare stent portion (23a). The SC branch-priority aortic reconstruction system includes a branch artery reconstruction assist device and a second stent body (50a), and the second stent body (50a) and the first stent body (20a) cooperate to seal and isolate the lesion. This prevents end leaks from the stent, ensures smooth access to each artery, and ensures normal blood flow to the brain and / or organs during surgery, avoids blood flow blockage, and reduces ischemic complications.

The invention discloses a hemostatic peptide capable of targeting to a bleeding focus as well as a preparation method and application of the hemostatic peptide, and the hemostatic peptide is characterized in that the amino acid sequence of the hemostatic peptide is RKLFFVRTA. According to the present invention, the key amino acid sequence combined with TF in the blood coagulation factor VII (FVII) is adopted as the basis for modification, the exposed TF (blood coagulation starting factor) after the blood vessel injury is specially identified, the specific expression of the TF at the bleeding site is adopted to achieve the precise targeting, the interference on the normal blood vessel is reduced, and the unnecessary thrombus risk is reduced from the source.

The present invention provides non-human animals expressing human CFB protein or chimeric (e.g., humanized) CFB protein and methods for using the same. The present invention further provides a non-human animal genome, a humanized CFB gene, and cells, tissues, organs, or non-human animals containing the non-human animal genome and the humanized CFB gene. The non-human animals obtained in this application successfully express human CFB protein or humanized CFB protein, which can be cleaved by CFD, bind to C3b, and exert similar effects in the human body. Furthermore, the non-human animals obtained in this application have complete renal function, normal blood biochemical indicators, and, more remarkably, do not exhibit the potential diseases observed in other transgenic mice known in this art.

The present application relates to the technical field of platelet aggregation detection, and specifically discloses a clinical platelet aggregation detection carrier, which comprises an instrument body and further comprises: a detection assembly arranged inside the instrument body, which is used for detecting different types of samples of lipemia, anemia and normal blood and selecting centrifugal operation of the blood samples; the detection assembly can detect different types of samples of lipemia, anemia and normal blood, and can automatically indicate whether centrifugal operation of the blood is needed according to the types of the detected samples; through the sampling assembly, the blood samples at different layer depths can be automatically adjusted according to the lipemia, anemia and normal blood samples detected by the detection assembly; through the agent adding assembly, the amount of the added inducing agent can be automatically adjusted according to the sample amount taken by the sampling assembly, so that the concentration of the mixed inducing agent reaches the specified range, thereby improving the detection accuracy of the platelet aggregation degree.

The application relates to the technical field of medicines, and discloses application of a traditional Chinese medicine composition in serum neurotransmitters, which comprises the following steps: selecting 6-8-week-old mice to establish normal models, chronic fatigue syndrome models and functional dyspepsia models; blood sampling is conducted on the mice of the normal models, the chronic fatigue syndrome models and the functional dyspepsia models to obtain normal blood samples, CFS blood samples and FD blood samples respectively; protein precipitation operation is conducted to obtain normal deproteinized supernatants, CFS deproteinized supernatants and FD deproteinized supernatants; separation is conducted by using a reversed-phase chromatographic column, and then mass spectrometry is conducted to obtain normal serum neurotransmitter mass spectra, CFS serum neurotransmitter mass spectra and FD serum neurotransmitter mass spectra respectively; concentration value calculation and rhythm fluctuation analysis are conducted to obtain a neurotransmitter function index and rhythm stability quantitative score respectively. Therefore, the mechanism of the traditional Chinese medicine composition in serum neurotransmitters is clearly quantitatively characterized.

A method for measuring a titer of a coagulation factor inhibitor. The-method includes: preparing a mixed specimen containing a-subject blood specimen and a normal blood specimen; heating the mixed specimen and acquiring a coagulation reaction-curve for the heated mixed specimen; acquiring a-coagulation reaction curve for the mixed specimen that has-not been heated; calculating a parameter related to the-coagulation reaction curve of the mixed specimen that has-not been heated as a first parameter; calculating a-parameter related to the coagulation reaction curve of the-heated mixed specimen as a second parameter; and-calculating a titer of a coagulation factor inhibitor in-the subject blood specimen on the basis of the ratio or the difference between the first parameter and the second-parameter.

The present application provides a kind of hemodialysis internal fistula nursing hemostasis device, comprising: adjusting box, adjusting box is fixedly installed with bandage;Lifting assembly, lifting assembly includes sleeve, screw and threaded sleeve, sleeve is rotatably arranged in adjusting box, screw is threadedly arranged in the small hole diameter inside of sleeve, threaded sleeve is threadedly arranged in the large hole diameter inside of sleeve, rotating sleeve can adjust screw and threaded sleeve move up and down, and the moving distance of screw is less than the moving distance of threaded sleeve;Pressing assembly, pressing assembly includes pressing block and pressing ring, pressing block and pressing ring are respectively fixedly installed in the lower end of screw and threaded sleeve, and pressing block is located in the inside of pressing ring.It can solve the technical problems that the pressure applied by the existing internal fistula hemostasis device is usually uniformly distributed in the covered area of pressing plate, which easily leads to the long-term unnecessary excessive compression of the normal blood vessel wall around the puncture point, significantly hinders the internal fistula blood flow, and increases the risk of thrombosis and internal fistula acute occlusion.

The invention discloses a peripheral leakage prevention stent device convenient to load and a heart valve, the peripheral leakage prevention stent device comprises a stent and is further provided with a flexible skirt edge, and the skirt edge has a spreading state in which the skirt edge axially extends and surrounds the periphery of the stent before being released; and in the stacking state, the annular peripheral leakage plugging part is driven by deformation when the stent is released and is folded and stacked in the axial direction of the released stent to form the annular peripheral leakage plugging part. By means of the peripheral leakage prevention technology, the interventional stent is more matched with the inner wall of a blood vessel, the stent is not prone to displacement and is more stable, the range of applicable people is widened, additional risks of operations are reduced, and complications such as peripheral leakage and thrombus are prevented and treated. Better hemodynamic performance is provided, the host endothelial cell climbing and covering function is enhanced, the occurrence probability of endocarditis is reduced, and the normal blood supply function of heart and blood vessels is recovered.

A blood purification system is provided that is capable of effectively utilizing accumulated histories stored during blood purification treatment and that helps quickly and accurately grasp whether the current transition of a particular parameter is normal when compared with a transition of the particular parameter that is estimated from the histories. The blood purification system includes an extracting device capable of searching histories accumulated in a storage device and extracting, as an approximate history, a history including the particular parameter approximate to the particular parameter observed at the current time in the current session of blood purification treatment; an estimating device that estimates a transition of the particular parameter to be observed after the current time in the current session of blood purification treatment from the approximate history extracted by the extracting device; and a display control device capable of displaying the transition of the particular parameter estimated by the estimating device and the transition of the particular parameter observed in the current session of blood purification treatment simultaneously on a display.

The invention provides a controllable cerebral blood flow adjusting device for cerebral blood flow reconstruction surgery, and relates to the technical field of medical instruments, the controllable cerebral blood flow adjusting device comprises a connecting elastic piece, and the two ends of the connecting elastic piece are connected with clamping pieces; the clamping piece is of an arc-shaped plate structure, and a traction piece is mounted at the bottom of the clamping piece; the connecting elastic piece, the clamping piece and the traction piece are made of polylactic acid-glycolic acid copolymer. When the device is used, under the assistance of ultrasonic waves, a traction sheet is used on a blood vessel to set proper clamping force so as to artificially cause blood vessel constriction, the inner-layer clamping sheet with different polylactic acid-glycolic acid copolymer proportions is used, the degradation speed of the whole device can be controlled and adjusted, then along with ordered degradation of the device, the clamping force on the blood vessel is gradually reduced, and the blood vessel constriction effect is improved. The constriction degree of the blood vessel is gradually reduced, and the blood vessel is finally recovered to a normal blood vessel diameter, so that the problems of headache, dizziness and other discomfort of a patient caused by intracranial blood flow over-perfusion are solved.

A sample slide preparation device and method are disclosed, wherein the sample transport device transports samples including trace blood samples and normal blood samples. A trace blood sample mixing device drives the movement of the trace blood sample to mix it. A normal blood sample mixing device drives the movement of the normal blood sample to mix it. A control unit determines whether the sample slide preparation device operates in normal blood mode or trace blood mode based on sample type information, and selects different methods to complete sample mixing, sample collection, and movement according to the different modes, finally preparing a sample slide for subsequent detection and analysis.

The invention relates to the technical field of medical instruments, in particular to a vascular intima stripping surgical device, a blade is rotatably connected to the inside of a U-shaped frame through a rotating rod and a bearing, one side of the rotating rod penetrates through the bearing and the U-shaped frame and extends to the outside of the U-shaped frame, a first gear is fixedly connected to the outer rod wall of the rotating rod, a fixing groove is formed in one side of an operating handle, and the fixing groove is fixedly connected to the operating handle. The inner wall of the fixing groove is fixedly connected with a first stepping motor with a self-locking structure, the output end of the first stepping motor is fixedly connected with a second gear, the second gear is meshed with the first gear, and the lower end of the side, away from the cutting edge, of the blade is fixedly connected with a telescopic arm with an adjusting buckle. The device has the beneficial effects that the second gear is driven by the first stepping motor to be meshed with the first gear, the angle of the blade is accurately regulated and controlled, and the device can be flexibly matched with different operation scenes by cooperating with the telescopic arm with the adjusting buckle; meanwhile, the elastic protection ring below the blade can effectively prevent the instrument from directly damaging normal vascular tissues.

The application provides a matrix balloon expansion system, belonging to the technical field of balloon catheters; the system comprises a catheter, a balloon assembly, a filling medium storage part and a flow control part; the balloon assembly is arranged at a position of the catheter close to a distal end at a set distance; the balloon assembly has multiple columns of balloon units arranged along the axial direction of the catheter; each balloon unit has multiple sub-balloon bodies arranged in the circumferential direction of the catheter; each sub-balloon body is used for independent inflation or deflation; the filling medium storage part is connected to the proximal end of the catheter and is used for providing filling medium into each sub-balloon body; the flow control part is connected to the filling medium storage part and is used for controlling the inflation or deflation of each sub-balloon body according to the pressure in the balloon assembly; and the system is mainly used for solving the technical problems that the shape of the whole balloon cannot be flexibly adjusted, normal blood vessels are easily damaged, and patients are obviously uncomfortable in the prior art.

The present invention relates to the field of medical device technology, and more specifically, to a semi-covered stent, a delivery system, and an operating method, wherein the semi-covered stent comprises a tubular stent, a coating provided on the tubular stent and covering only a portion of the surface of the tubular stent, a first developing member provided at both ends of the tubular stent, and a second developing member provided at the edge and / or middle of the coating. The purpose of the present invention is to overcome the deficiency that the current covered stents are all completely covered in the circumferential direction, and the membrane on the stent affects the blood flow of normal blood vessels when treating aneurysms at bifurcated blood vessels. The coated side of the semi-covered stent of the present invention can effectively prevent blood from flowing into the aneurysm, and the uncoated side will not affect the blood flow of normal blood vessels. It has a better therapeutic effect on the treatment of aneurysms at bifurcated blood vessels and reduces the occurrence of postoperative embolism.

An implantable medical device for implantation within a patient includes one or more sensors configured to sense an optical signal. Processing circuitry of the implantable medical device or of an external device may determine a blood pressure of the patient based on the optical signal sensed after the patient undergoes an invasive surgery, determine, based on a normal blood pressure range or a normal rate of blood pressure change over a particular period of time, that the blood pressure of the patient is abnormal, and, in response to determining that the blood pressure of the patient is abnormal, output an alert indicative of the blood pressure of the patient being abnormal.

The invention discloses a body surface monitoring management method and system for dynamically monitoring the blood ammonia level, relates to the technical field of blood ammonia detection, and solves the problems that in blood ammonia detection in the prior art, targeted data setting and detection frequency setting are not performed on different types of people; and the accuracy degree of the alarm signal and the complexity degree of detection are influenced. The method comprises the following steps: firstly, acquiring a historical blood ammonia level record and real-time blood ammonia level data of a to-be-detected person as well as personality information and disease information of the to-be-detected person; then classifying the personnel based on personal information and disease information of the personnel, and setting an alarm signal based on a normal level range or a conventional fluctuation range and a fluctuation direction of blood ammonia; and finally, the detection frequency is adjusted based on the signal types and the number. In conclusion, a more accurate and efficient detection scheme can be formulated according to the characteristics and requirements of different people in combination with the individualized medical concept, and the blood ammonia level monitoring difficulty can be reduced.

The embodiment of the invention provides a stenosis assessment method and device based on multi-parameter fusion, a medium and a program product, and relates to the field of intelligent medical treatment. The method comprises the steps of obtaining a geometric model of a to-be-tested blood vessel; positioning a narrow section according to the geometric model; calculating geometric data of the cross section of the narrow section, and calculating a compactness coefficient based on the geometric data; calculating an asymmetric coefficient of the narrow section; calculating an irregularity coefficient based on the compactness coefficient and the asymmetric coefficient; calculating the stenosis rate of the stenosis section according to the average cross-sectional area of the stenosis section and the average cross-sectional area of the normal blood vessel; and calculating the product of the stenosis rate and the irregularity coefficient to obtain the comprehensive stenosis. According to the comprehensive stenosis quantification method based on the compactness coefficient and the irregularity coefficient of the blood vessel section, the limitation that a traditional method depends on a single area or diameter index is broken through by fusing multi-dimensional parameters of the geometric morphology of the section.

Provided herein are red blood cell control compositions comprising one or more populations of lysable hydrogel particles having an impedance that is substantially similar to the impedance of a human red blood cell of average diameter; and a population of hemoglobin molecules or a population of dye molecules that have substantially similar absorbance as hemoglobin; wherein (i) and / or (ii) are present in an amount that corresponds to a normal blood sample or disease state, or (i) and (ii) are present at a ratio that corresponds to a normal blood sample or disease state.

The application provides a microfluidic device for sorting circulating tumor cells and enriching exosomes. It comprises a fixed plate, a first sorting module for separating cells and exosomes, an enrichment module for enriching exosomes, and a second sorting module for sorting normal blood cells and circulating tumor cells. The inlet of the enrichment module is connected to the exosome outlet of the first sorting module, and the inlet of the second sorting module is connected to the cell outlet of the first sorting module. The inlet of the sorting module is also provided with a sheath liquid input module for inputting sheath liquid to the second sorting module. The microfluidic device can separate cells and exosomes by using synergistic Dean flow microfluidic inertial sorting, then realize efficient enrichment of exosomes by using a pit-assisted thermal field, and separate tumor cells and normal cells by using deterministic lateral displacement technology (DLD) combined with insulating dielectrophoresis technology (i DEP).