319 results about "Normal blood" patented technology

In an effort to reduce employer health insurance related costs, at least one benefit under a health benefit plan is conditional on the employee voluntarily participating in a wellness program. The wellness program could include wellness categories such as a tobacco free category, normal blood pressure category, regular exercise category, a non-overweight category, a healthy cholesterol level category, a healthy blood glucose level category, and possibly even a category for participation in a health risk assessment. The invention may be implemented by an employer adopting a health plan with a higher deductible over a previous year, and providing credits against that deductible for employees who satisfy requirements regarding each of a variety of wellness categories. This should enable the employer to realize an immediate savings in the year that the invention is implemented, and future savings in years thereafter from healthier employees having lesser numbers of claims and smaller dollar claims.

The invention relates to the use of angiotensin II receptor antagonists for treating people in whom type 2 diabetes mellitus has been diagnosed or who are suspected of prediabetes, for preventing diabetes or for treating metabolic syndrome and insulin resistance in patients with normal blood pressure.

Disclosed is a medical device that operates as a supporting splint for the limbs and other body parts necessary for the treatment of a variety of medical and surgical conditions. Said device is an inflatable, flexible, lightweight water-resistant splint whose measure of rigidity is easily controlled by the fitter or user. According to the present invention there are several embodiments of the splint, each suited to fit a different body part such as the limbs, torso, chest, pelvis, and neck. Said device, which is constructed of inflatable tubes, is made of two nylon layers welded together and coated with polyurethane. The tubes may be inflated by any means of supplying air pressure. The present invention is especially designed to allow normal blood circulation to the treated body part, provide ventilation to the area, enable easy inspection of an injury, and allow partial movement of the treated part.

The invention discloses a covered stent, which comprises a support structure and a tectorial membrane unit, and is characterized in that: the tectorial membrane unit comprises an inner-layer tectorial membrane and an outer-layer tectorial membrane which coats the support structure; the outer-layer membrane coats on the outer side of the inner-layer tectorial membrane; the inner-layer tectorial membrane is a biological membrane with good blood compatibility, and the outer-layer tectorial membrane is a biological membrane which is easy to induce the formation of thrombus; the inner-layer tectorial membrane contacting blood has good blood compatibility, can effectively reduce the formation of the thrombus, and maintains normal blood flowing channels; and the outer-layer tectorial membrane can induce the formation of the thrombus in aneurysm or thrombus of bleeding parts, promotes the aneurysm to be quickly activated and reduced, reduces the mass effect in vivo, simultaneously effectively adheres endothelial cells, promotes differentiation and proliferation of cells, quickens the endothelialization of lesion parts of vessels, and can more effectively treat vascular diseases such as the aneurysm and the like.

A system, apparatus and methods are provided for extra-corporeal blood treatment, and in particular for establishing and maintaining a neck down differential body temperature, while maintaining near normal brain temperatures, to protect the brain from extended or extreme hypothermia or hyperthermia. A blood treatment apparatus and system is provided for differential control of brain temperature and body temperature below the neck. For example, a first bypass circuit with heat exchanger for brain blood circulation maintains a near normal blood temperature, while a second bypass circuit for below the neck blood circulation provides for thermal treatment to induce a temperature differential, e.g. hyperthermia or hypothermia, relative to brain circulation. Such systems and apparatus have application, for example, for diagnostic and therapeutic treatments using hyperthermia, particularly for treatments of extended duration or at elevated temperatures above 42° C., for example, hyperthermia for treatment of cancer, infectious bacterial or viral diseases.

A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g., pH of 7.0 to 7.4, and contains bicarbonate at a concentration that is found in normal blood. Additionally, the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5.0.

In an effort to reduce employer health insurance related costs, a state-governed fully-insured health insurance policy is provided for a group of employees. At least one benefit under the health insurance policy is conditional on the employee voluntarily participating in a wellness program. The wellness program could include wellness categories such as a tobacco free category, normal blood pressure category, regular exercise category and even a non-overweight category. In addition, the wellness program could condition coverage, or subsidize deductibles for, certain illnesses on employee submission to screening tests on a prescribed basis for the identified illness, such as cancer screening for early detection of cancer. The voluntary wellness program can also include a variety of other aspects including wellness education, disease inoculation, and injury prevention. The invention provides an incentive for employees to make healthier lifestyle choices.

The invention discloses a blood flowing detection device and method. The detection device comprises an inflation pressure binding belt, a detection host, as well as a temperature sensor and a humidity sensor which are connected with the detection host; and the detection host comprises a control button, a switching voltage-stabilized power supply circuit, a singlechip microcomputer central control-processing unit, a preamplifier, an A / D (analog-to-digital) conversion circuit, a display and a buzzer. The detection method comprises the following steps: releasing restriction after a blood flow atthe proximal end of a heart is restrained for a certain period of time; measuring changes of skin temperature and humidity on a position at a distal end of the heart, and comparing the changes with the standard parameters of people with a normal blood flowing condition; determining whether a testee has vascular endothelial dysfunction or not; and evaluating the severity of early symptoms of cardiovascular sclerosis and hemodynamics of the testee. The detection device has the advantages of simple structure, low cost and convenience for operation, causes no trauma or pain, and can be used for routine physical examination and community general examination.

The invention provides a bayberry polyphenol flavone extract, which is obtained by the methods as follows: the fragment of a bayberry plant is used as raw ingredient, ethanol water solution of 50 to 80 percent is added, wherein, the ethanol water solution is 4 to 7 times of the quality of the fragment; the mixture is extracted for 1 to 3 hours at 60 to 100 DEG C in a heat preservation way and is filtered to obtain extracting solution; the volume concentration of alcohol in the extracting solution is adjusted to reach 75 percent to 80 percent; the extracting solution is mixed well, let stand for 0.5 to 2 hours, and then filtered; the alcohol is recovered from filter liquor and is concentrated to obtain macroporous adsorption resin on a paste; the macroporous adsorption resin is eluted by using distilled water, then by using the ethanol water solution of 10 to 20 percent to remove impurities, and then by using the ethanol water solution of 60 to 90 percent at last; eluate is collected to recover the alcohol which is dried until the liquid water content is less than 12 percent, so as to obtain the bayberry polyphenol flavone extract. The invention provides the bayberry polyphenol flavone extract which has three-fold efficacy, namely assistance efficacy on blood lipid reduction, hypoglycemic efficacy, and blood-pressure reduction efficacy, and no similar products are developed and manufactured until now. Compared with existing products at home and abroad, the bayberry polyphenol flavone extract has more overall efficacies, and better effect for regaining normal blood-fat, blood sugar and blood pressure of people in need.

Disclosed is a medical device which operates as a supporting splint for the treatment of orthopedic conditions. Said device is an inflatable, flexible, lightweight water-resistant splint whose measure of rigidity is easily controlled by the user. According to the present invention there are several embodiments of the splint, each suited to fit a different body part such as the limbs, the torso, the chest and the neck. Said device which is constructed of inflatable tubes is made of two nylon layers soldered together and is coated with polyurethane. The tubes may be inflated by an attachable hand pump or by other means of supplying air pressure. The present invention is especially designed to allow the normal blood circulation to the treated body part, provide ventilation to the area and enable easy inspection of an injury.

A process for treating tumors by administering a mixture of cancer fighting drugs incorporated into a stabilized liposomal formulation. Each cancer drug is selected to target a different phase of the cell-cycle of the cancer cell thus expanding the number of cancer cells that can be killed at one time without compromising the safety of the patient. The stabilized multi-drug liposomes are designed to extravasate thru “leaky” blood capillaries supplying the tumor and enter the tumor tissue where they will accumulate over time and ultimately released to kill surrounding tumor cells. The multi-drug liposomes are likewise unable to extravasate thru normal blood capillaries and will thus be less toxic to normal tissues.

The invention relates to Lactobacillus helveticus H9 and application of the Lactobacillus helveticus H9 to the resistance of hypertension and the prevention of cardiovascular disease. A preparation method comprises the following steps of: isolating strains, identifying the strains, preserving the strains, culturing the strains, preparing a bacterial liquid, preparing fermented milk, and screening a strain with angiotensin-converting enzyme (ACE) inhibitory activity; and further evaluating the influence of Lactobacillus helveticus H9 fermented milk on hypertension (SHR, spontaneously hypertensive rats) and normal blood pressure (WHY rats, Wistar-Kyoto rats). The research shows that strain fermented milk has a better in-vivo antihypertensive effect, has the advantages of long onset time and the like, does not affect blood circulation, and has no adverse effects on the normal blood pressure.

The invention provides nucleic acids, peptides, and antibodies for use in applications including diagnosis and therapy. The peptides target neovasculature and were identified by in vivo phage display. One such peptide, SP5-52, recognized the neovasculature of multiple tumors in SCID mice, but did not target normal blood vessels. This peptide also binds to blood vessels of human lung cancer biopsy specimens. Liposomes comprising SP5-52 and doxorubicin enhanced the efficacy of the drug against multiple human cancer xenografts in SCID mice.

The invention discloses a local circulation type thrombus removing device. The local circulation type thrombus removing device mainly comprises an impeller assembly used for smashing the thrombus, a head end protective pipe, an inner pipe, an outer pipe, a first Y-shaped valve and a second Y-shaped valve. A first annular cavity is formed between the inner pipe and the impeller assembly, a second annular cavity is formed between the outer pipe and the inner pipe, the first Y-shaped valve is provided with a fluid infusion connector used for being connected with a fluid infusion pump, the fluid infusion connector is communicated with the second annular cavity, the second Y-shaped valve is provided with a thrombus removing connector used for being connected with a thrombus sucking pump, and the thrombus removing connector is communicated with the first annular cavity. The local circulation type thrombus removing device can improve the thrombus removing rate, prevent the venous intima from being injured, completely discharge the thrombus broken grains out of the body and prevent normal blood from excessive loss. The local circulation type thrombus removing device is especially suitable for removing the human body deep femoral vein thrombus by the adoption of the percutaneous minimally invasive surgery.

The invention discloses an ACE inhibitory peptide and a preparation method thereof, and provides a casein hydrolysate which has an anti-hypertension effect and is rich in the ACE inhibitory peptide, the ACE inhibitory peptide with an anti-hypertension effect, and a preparation method of the ACE inhibitory peptide. The casein hydrolysate rich in the ACE inhibitory peptide contains two peptide fragments with ACE inhibitory activities; and the amino acid sequences of the two peptide fragments with ACE inhibitory activities are respectively YS and YQKFPQYLQY. The amino acid sequence of the ACE inhibitory peptide is YS or YQKFPQYLQY. The ACE inhibitory peptide or the casein hydrolysate rich in the ACE inhibitory peptide is sufficiently mixed with milk powder matrixes to prepare anti-hypertension milk powder; or the ACE inhibitory peptide or the casein hydrolysate rich in the ACE inhibitory peptide is mixed with fresh milk to obtain a mixture, and lactic acid bacteria is inoculated in the mixture to obtain yoghourt with an anti-hypertension effect. The dairy product has a remarkable anti-hypertension effect, has no influence on the normal blood pressure, is safe to eat, and is suitable for being ate by the hypertension groups.

Prophylactic or therapeutic treatment to inhibit the development or progress of multiple sclerosis symptoms is provided by providing intermittently administered elevated doses of calcitriol, sufficiently infrequently to avoid hypercalcemia. Such methods may include maintaining at least about a normal blood level of vitamin D3 as evidenced by a 25-(OH)D3 level of at least about 50 nmol / L.

The invention discloses preparation and application of a tumor marker calreticulin detection kit, and belongs to the fields of genetic engineering and clinical diagnosis. A monoclonal antibody and a polyclonal antibody of the CRT (calreticulin) are prepared by recombinant CRT genetic immune BALB / c mice and new Zealand white rabbits; and an ELISA (enzyme-linked immunosorbent assay) kit with high specificity and sensitivity of which the lowest CRT content is 0.3125ng / ml and the detection limit is 40-0.3125ng / ml is built. The collected clinical sample is detected through the prepared ELISA kit; the result shows that CRT in blood serum of a patient with lung cancer is obviously higher than that in normal blood serum; significant statistic difference exists (P is smaller than 0.01); and an experimental method is provided for diagnosis of the clinical patients with lung cancer.

The invention discloses a medicament for treating diabetic complications and a preparation method thereof. The medicament is mainly prepared from astragalus, polygonum orientale, gypsum, honeysuckle, figwort root, szechwon tangshen root, Chinese angelica, rehmanniae praeparatum, cassia bark, Indian buead, large-headed atractylodes rhizome, white paeony root, plantain seed, raw cinnamomvine, notoginseng root and liquorice root according to a certain weight ratio, and can be prepared into any common formulations. The medicament of the invention has obvious curative effect on the treatment of the diabetic complications and obvious effect of antidiabetics, promotes blood circulation, absorbs extravasated blood of fundus quickly, rehabilitates blood vessels and restores vision. In addition, for patients who suffer from gangrene, the medicament can eliminate polyneuropathy, invigorate podiatric thrombus quickly to form normal blood circulation and cure wounds, and the patients do not need amputation; and the diabetic complications become effective completely within one month, the cure rate of fundus hemorrhage (before laser treatment) within three months is 88 percent, the cure rate of nephropathy is 82 percent, the cure rate of the polyneuropathy is 85 percent, the cure rate of the gangrene is 89 percent, and the comprehensive cure rate of other symptoms is 84 percent. Until now, the diabetic complications are difficult to relapse from the follow-up period, and the medicament is well received by the patients.

The present invention discloses an aortic-arch-with-branch covered stent blood vessel combined device. The aortic-arch-with-branch covered stent blood vessel combined device comprises three artificialblood vessel components: (1) a segment of a U-shaped artificial aortic blood vessel with three branches, wherein the main blood vessel at a left part of the branch is internally provided with a stent; (2) small covered stent blood vessels; and (3) a straight cylindrical stent blood vessel with a segment of a bare stent and a segment of a covered stent. The blood vessel components can isolate aortic lesions involving aortic arch and ascending aorta, at the same time rebuild branch arterial blood flow, and can preserve normal blood vessel morphology to a greatest extent. The aortic-arch-with-branch covered stent blood vessel combined device is suitable for various common branch-shaped blood vessels and wide in application ranges, avoids custom stents, can be subjected to mass production, effectively reduces surgical trauma, and is easy in surgery operations.

The invention belongs to field of medical examination and relates to assay determination method of internal medicine, specially a detecting method of six antiepileptics medicines of primidone, phenylethylmalonylurea, diphenylhydantoin, carbamazepine, Larmortriazine, okazepine and the active product monohydroxy okazepine of okazepine and the active product epoxy carbamazepine of carbamazepine in human plasma. The sample to be measured is eluted equicontinuously in condition of acidic mobile phase via the pretreatment of protein precipitation, and separated by chromatographic column, and detected by ultraviolet detector. The quantity of sample in the invention is small; the pretreatment method is simple, fast and sensitive, free of expensive apparatus and agents, applicability is wide, cost is low, it fits for the detection of normal blood concentration in clinic.

A method and apparatus for reducing the thickness of arterial walls is disclosed. Ablation of the exterior layer of the arterial walls is performed using mechanical or laser ablation techniques. Surveying is preferably carried out during the procedure to ensure optimal ablation. The ablation reduces the effective thickness of the arterial walls and increases flexibility so that the walls distend under normal blood pressure, thereby improving blood flow. Advantageously, the procedure is carried out without invasion of the blood vessel lumen and without damage to the inner layer of the artery wall.

The adhesive film preparation consists of back lining material, medicine layer and protecting film, and the medicine layer is fixed to the back lining material via two opposite adhesive edges or some regularly distributed points around it. The medicine layer consists of skeleton supplementary material in 20-30 wt%, effective medicine components in 60-75 wt% and plasticizer in 5-10 wt%, and is 0.13-0.5 cm in thickness. The adhesive film preparation has no influence on the blood circulation, metabolism and secretion of the skin in the applied part, no allergy, great medicine carrying amount, fast medicine release, effective transdermal absorption for great concentration of medicine in blood to reach the aim of curing internal disease via external application. The preparation process of the adhesive film preparation is also disclosed.

The invention relates to a system for detecting plaques in blood vessels, comprising a blood vessel feature model learning unit, a ROI image capture unit, and an abnormal image generation unit. The blood vessel feature model learning unit is used for constructing a blood vessel feature model based on a first set of sample images including a plurality of normal blood vessel sample images. The ROI image capture unit is used for capturing the ROI of a blood vessel image to be detected. The abnormal image generation unit is used for comparing the difference between the ROI of the blood vessel image to be detected and the blood vessel feature model and generating an abnormal image according to a difference result obtained from comparison. The invention further relates to a method for detecting plaques in blood vessels.

A method for selecting and locating the blood vessel scaffold includes choosing at least one narrow segment of blood vessel, determing the positions of its both ends, extracting its narrow data, marking its profile, extracting its profile data, automatically drawing the profile of normal blood vessel according to the positions of its both ends, extracting its profile data, comparing the narrow data with the normal data, calculating the data about scaffold, and regualting and determing the position and length of scaffold. Its system is also disclosed.

The invention provides an instrument for removing tumor cells in circulating blood. The therapeutic instrument, which is communicated with the in-vivo circulating blood, effectively removes the tumor cells in the blood by utilizing antibody and performs in-vitro immunity treatment to block the route of the hematogenous spread of malignant tumor. The invention adopts a technical scheme that: the instrument for removing the tumor cells in the circulating blood comprises an input catheter, a medicinal peristaltic pump, a tumor cell remover and an output catheter, wherein the input catheter, the medicinal peristaltic pump, the tumor cell remover and the output catheter are connected with one another sequentially; and the input catheter and the output catheter are connected with the blood vessel of a human body or an animal. The tumor cell remover has the following structure that: a cylindrical outer tube is provided with polystyrene cellosilk inside; a filter screen is arranged at the outlet of the outer tube; and the antibody is coated by the polystyrene cellosilk. The instrument for removing the tumor cells in the circulating blood has the advantages of safe, accurate, timely, continuous and effective removal of the tumor cells, synchronization therapy, obvious improvement of the symptom of a patient, no damage to normal blood cells of the patient in a continuous therapeutic process, low manufacturing cost, simple and convenient operation, practicability and economy, and capacity of relieving the pain of a tumor patient and reducing the burden of the therapy for the patient.

The invention discloses a flavor rice wine containing Fructus Tsaoko and coffee. The flavor rice wine containing Fructus Tsaoko and coffee is composed of the following raw materials, by weight, 100-105 parts of rice, 5-7 parts of Fructus Tsaoko, 10-14 parts of sweet potato powder, 7-8 parts of coffee powder, 4-5 parts of lotus leaf, 2-3 parts of Gynostemma pentaphylla, 2-3 parts of an apple, 1-2 parts of Achyranthes aspera L., 2-3 parts of sunflower receptacle, 2-4 parts of ginseng leaf, 1-2 parts of Bunge Corydalis Herb, 2-3 parts of dry ginger, 2-3 parts of dahurian angelica root, 0.6-0.8 parts of citric acid, and 10-15 parts of distiller's yeast. The flavor rice wine containing Fructus Tsaoko and coffee produced in the invention breakthroughs the mouthfeel of a traditional rice wine, has a sweet and mellow fragrance and has very high healthcare values, Fructus Tsaoko can relieve coughs, eliminate phlegm, and resist bacteria and inflammations, and dahurian angelica root has the efficacies of wind and cold dispelling, consciousness restoration promoting, pain relieving, blood circulation invigorating, pus expelling, flesh engendering, dampness drying and vaginal discharge stopping. The flavor rice wine containing Fructus Tsaoko and coffee has the efficacies of fat reduction, beauty treatment, normal blood pressure and heart function maintenance, and the like, and is beneficial for the health of human bodies.

The invention discloses an intravascular ultrasound image three-dimensional reconstruction method and a system based on deep learning, and the method comprises the steps: collecting a bifurcated bloodvessel image and a normal blood vessel image in an IVUS image, carrying out the labeling, and making a first data set; classifying the first data set by using a classification network to obtain a bifurcated blood vessel image and a normal blood vessel image; respectively marking the inner and outer membranes of the bifurcated blood vessel image and the inner and outer membranes of the normal blood vessel image to form a second data set and a third data set; respectively segmenting the second data set and the third data set by utilizing a semantic segmentation network to respectively obtain inner and outer membrane images of the bifurcated blood vessel and the normal blood vessel; and performing three-dimensional reconstruction on the obtained inner and outer membrane images of the bifurcated blood vessel and the normal blood vessel. According to the method, bifurcated blood vessels and normal blood vessels are classified by using a deep learning method, so that the speed and accuracyof three-dimensional reconstruction can be improved, the reconstruction result is more accurate, intuitive judgment of doctors is facilitated, and the method is of great significance to auxiliary diagnosis of diseases.