587 results about "Blood supply" patented technology

Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving one or more vascular models associated with either the patient or with a plurality of individuals; receiving observed perfusion information associated with the patient; and estimating, using one or more computer processors, one or more blood flow characteristics or one or more pathological characteristics of the patient based on the observed perfusion information and the one or more vascular models.

The invention is a delivery catheter, e.g., a guide catheter, having an imaging element in proximity to the distal end of the catheter. Catheters of the invention are able to placement of the catheter in proximity to an ostium, thereby increasing the efficiency of contrast delivery while reducing the risk of ischemia due to blocked blood supply. The invention additionally assists in maintaining catheter position during delivery of a fluid from the catheter, resulting in better performance with less fluid. For example, a catheter of the invention can be used to produce improved fluoroscopic images with less overall contrast. This improvement reduces the risk of an allergic reaction to the contrast while decreasing the length of time for a procedure, i.e., because of a need to re-contrast.

Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.

Systems and methods are disclosed for diagnosis, risk assessment, and / or virtual treatment assessment of visceral ischemia and related disorders. One method includes receiving a patient-specific anatomic model of a patient's visceral vasculature, including visceral vasculature of the patient's visceral organs and bowel; determining a location in the patient-specific anatomic model of the patient's visceral vasculature; determining, for the location in the patient-specific anatomic model, a blood flow characteristic of blood flow through the location in the patient-specific anatomic model of the patient's visceral vasculature; determining a tissue region of the patient's bowel proximate the location in the patient-specific anatomic model of the patient's visceral vasculature; and generating an assessment of blood supply adequacy to the tissue region of the patient's bowel based on the determined blood flow characteristic and an expected blood flow characteristic associated with the tissue region of the patient's bowel.

The invention belongs to the related technical field of medical health monitoring, and particularly relates to a flap blood supply monitoring and early warning system and method based on a wearing technology, and the system specifically comprises a wearable blood supply monitor of a client and a cloud real-time flap state monitoring platform of a medical end. The wearable blood supply monitor comprises a front-end flexible sensor used for detecting flap state indexes and communicating with a rear-end host in real time; and the rear-end host is used for sensor data processing and visualization, and is in real-time communication with the front-end flexible sensor and the cloud real-time flap state monitoring platform. And the cloud real-time skin flap state monitoring platform analyzes client data in real time, adopts a current machine learning model for classification to divide the skin flap blood supply state, and obtains a final skin flap blood supply state classification result through a voting mechanism. Compared with a traditional blood supply monitoring mode, microcirculation changes of the skin flap can be monitored in real time, the blood supply state of the skin flap can be intelligently judged, and the blood supply monitoring efficiency, accuracy and reliability are effectively improved.

The invention relates to the technical field of intelligent medical systems, and discloses a cerebral apoplexy onset risk assessment and reminding method and system.The method comprises the steps that continuous medical structured detection data are collected, and the data comprise carotid artery blood flow parameters, brain oxygen saturation, heart rate variability and metabolic indexes; inputting a bidirectional LSTM, a differential convolutional network, a wavelet residual network and a multi-layer perceptron to extract nonlinear features; constructing a neural function coupling structure diagram of four nodes of cerebral blood supply, oxygen supply, autonomous regulation and metabolic steady state; calculating inter-node time sequence offset correlation and a stable factor to obtain a coupling anomaly coefficient; and driving the embedded network by using a graph structure and a node feature input mechanism, and outputting a risk state assessment result. According to the method, the neural function coupling structure diagram is constructed and the mechanism is introduced to drive the embedded network, so that high-precision identification of the multi-system collaborative abnormal state and dynamic evaluation of the stroke risk level are realized.

The invention provides a whole blood donor low hemoglobin delayed blood donation risk prediction method, which comprises a data normalization and abnormal value processing module, a classification feature coding module, a category balance and model fitting module, a hyper-parameter adjustment module and a model interpretation and deployment module. According to the prediction method provided by the invention, data normalization and targeted feature coding are carried out on blood donation records and hemoglobin detection data, an SMOTE oversampling algorithm is used for class balance and then fitting of a Light GBM model is carried out, and a Hyperband hyper-parameter adjustment method is used for adjusting and optimizing SMOTE and Light GBM parameters. And storing the tuning model for feature importance interpretation, model packaging and network deployment, thereby realizing the effects of optimizing the whole blood donor invitation strategy and enhancing the continuity and stability of blood supply.

The invention provides a balloon dilatation catheter, and belongs to the technical field of balloon dilatation catheters. The balloon dilatation catheter comprises a catheter body, the far end of the catheter body is provided with a balloon body used for dilating a narrow part, and the near end of the catheter body is provided with an operating handle used for charging and discharging a filling medium into the balloon body. A flow channel allowing blood to penetrate through is formed in the balloon body and / or between the balloon body and the outer side wall of the catheter body in the axial extending direction of the catheter body, in the working process, after the balloon body is filled, a narrow part is treated, and the blood in the narrow part penetrates through the flow channel to continue to be circulated. The balloon is mainly used for solving the technical problems that in the prior art, when a balloon dilates, blood flow is blocked, consequently, far-end blood supply is insufficient, and the drug transfer effect is affected due to insufficient contact time of the balloon and the blood vessel wall.

The invention provides a clinical diagnosis and treatment path generation method and system for tracking a chest pain patient. Wherein a dynamic spatio-temporal data atlas is constructed by synchronously collecting respiratory rhythm phase difference, coronary artery calcification integral and hypersensitive troponin curve slope, and risk degree transition signals are generated by coupling analysis of ST segment elevation amplitude asymmetric growth, left ventricular ejection fraction attenuation gradient and B-type natriuretic peptide release rate. In the acute stage, the constraint relation between a vascular recanalization time window and thrombolysis taboo is dynamically bound, in the subacute stage, a phase synchronization rule for enhancing CT scanning and anticoagulant drug dosage is established through a multidisciplinary interface, intravascular ultrasonic plaque morphological mutation characteristics and extracorporeal circulation parameters are fused, the blood supply reconstruction time sequence is dynamically adjusted based on a myocardial oxygen consumption balance equation, and the thrombolysis time sequence is determined. And path self-optimization is realized through space-time superposition of an interventional therapy delay parameter and a drug metabolism curve. According to the technical scheme provided by the invention, chest pain diagnosis and treatment path dynamic optimization and multi-modal parameter collaborative decision-making are realized, and the risk layering precision and the treatment timeliness are improved.

The invention discloses a brain health monitoring and cerebral infarction early warning method and system for old people. The method comprises the steps that electroencephalogram, electrocardio, blood oxygen and cerebral blood flow velocity multi-mode physiological signal data are collected; adopting a characteristic mode decomposition method to decompose the multi-mode physiological signal data; the method comprises the following steps: introducing a KAN network into an MATE structure, carrying out nonlinear mapping and feature reconstruction, and constructing a KAMATE model; an improved Bayesian optimization algorithm is obtained based on the Bayesian optimization algorithm in combination with a dynamic balance strategy; the improved Bayesian optimization algorithm is combined with the characteristic mode decomposition method to achieve characteristic decomposition of the multi-mode physiological signals, and parameters of the KAMATE model are optimized; dividing the brain health state into four grades according to a prediction result output by the KAMATE model; according to the invention, real-time early warning of abnormal cerebral blood supply, cognitive decline and cerebral infarction high-risk states of the elderly can be realized, intelligent support is provided for health management of the elderly, and the method has important application value.

The invention discloses a blood component separation system and a control method, and belongs to the field of blood separation.The system comprises a centrifugal device, a blood supply pipeline, an air detector valve and a blood pump, a liquid outlet of the centrifugal device is connected with a separation pipeline, and the separation pipeline is sequentially connected with a first plasma bag and a second plasma bag; a centrifugal pressure sensor, a centrifugal high-speed camera and a red blood cell sensor; and the control center comprises a data acquisition module, a data analysis module and a centrifugal control module. The control method comprises steps S1 to S4. Dynamic intelligent regulation and control and automatic control of the blood component centrifugal separation system are achieved, the centrifugal effect is optimized through the image recognition technology, the image recognition technology is superior to the photoelectric recognition technology in the prior art, excessive centrifugation is avoided, meanwhile, the centrifugal quality is guaranteed, and the quality and activity of separated blood components are effectively guaranteed.

The invention discloses a method for controlling the compaction degree of a left heart and a right heart in an extracorporeal circulation operation, which comprises the following steps of: in an in-vitro environment, mounting a peristaltic pump at a left heart inlet and a right heart inlet of an extracorporeal circulation device; a liquid inlet of the peristaltic pump is connected with a liquid inlet pump, and a liquid outlet of the peristaltic pump is connected with a liquid outlet pump; and finally, a first pressure measuring structure and a second pressure measuring structure are arranged on the sides, away from the peristaltic pump, of the liquid inlet pump and the liquid outlet pump correspondingly, and the pressure of the liquid inlet pump and the pressure of the liquid outlet pump are adjusted to be-20 mmHg. The negative pressure of the liquid inlet pump is adjusted through the first pressure measuring structure, and the negative pressure of the liquid outlet pump is adjusted through the second pressure measuring structure, so that the purpose of quantifying the adjusting mode is achieved, and the adjusting mode is accurate, rapid and high in reliability; the peristaltic pump can effectively avoid the occurrence of risks such as blood component damage, hemolysis, gas embolism and the like caused by reduction of the amount of blood conveyed by the pump, insufficient blood supply or direct interruption of blood circulation due to the condition that a pipe body connected with the peristaltic pump is shrunken or cannot be sucked during an operation.

The invention discloses application of MUC12 gene in preparation of drugs for reducing rectal cancer liver metastasis, and belongs to the technical field of medical biology. According to the invention, the clear relation between colorectal cancer liver metastasis and fructose metabolism reprogramming is revealed from a molecular mechanism for the first time. The invention provides a brand-new therapeutic target and strategy by determining the brand-new transfer promoting factor MUC12 and the mediated fructose metabolism regulation effect thereof. Different from the traditional therapy only aiming at the strategies of tumor cell proliferation, blood supply and the like, the method disclosed by the invention intervenes aiming at a tumor nutrition metabolic pathway, and can weaken the metabolic adaptation and proliferation capacity of metastatic tumor cells in the liver more specifically. Experimental results show that the functions of targeted inhibition of MUC12 or downstream fructose metabolism key enzymes KHK and ALDOB thereof can significantly reduce the invasion and metastasis ability of tumor cells, and at the same time, normal growth of primary tumors cannot be significantly affected.

The invention belongs to the field of biological medicines, and discloses an application of Akkermansia muciniphila or an extracellular vesicle of the Akkermansia muciniphila in preparation of a medicine for alleviating the ischemic necrosis of the alcoholic femoral head. Based on the pathogenesis characteristics of the AIONFH, the Akk bacteria and the extracellular vesicles thereof are used for treating the AIONFH for the first time, the molecular mechanism of the Akk bacteria and the extracellular vesicles thereof for regulating and controlling the intestinal tract-skeleton axis function, inhibiting bone cell apoptosis and improving the bone trabecula microstructure is deeply researched, the anti-pressure ability of bone tissue is improved, and the research blank in the field is filled. Compared with a traditional treatment method, the osteonecrosis pathological change is improved through a single way, and a novel multi-target treatment strategy is provided from multiple aspects of regulating inflammatory response, recovering bone metabolism balance, promoting intraosseous blood supply and the like.

A protective umbrella and intracavity umbrella ribs are coaxially arranged on a conveying guide wire of the far-end embolism protection device, a supporting bracket of the protective umbrella is of a hollow structure, two first openings are formed in the near end of the supporting bracket and are symmetrically arranged along the central axis of the supporting bracket, and a covering film is fixed to the far end of the supporting bracket and wraps a part of the far end of the supporting bracket; a plurality of holes are formed in the covering film, the intracavitary umbrella ribs are located in the supporting support and are of a hollow structure, and second openings of the intracavitary umbrella ribs face the far end of the supporting support. The intracavity umbrella ribs and the covering film form a double-layer filtering structure, so that the situation that thrombus clots are accumulated in the inner cavity of the protection umbrella is effectively improved, the probability that meshes / micropores of the protection umbrella are blocked is reduced, and sufficient blood supply of a nervous system is ensured; the intracavitary umbrella ribs and the supporting bracket are coaxially arranged, so that the stability of the protective umbrella in the blood vessel is improved, the protective umbrella is not prone to inclination, and effective capture of free thrombus is ensured; the arrangement of the two first openings ensures that an effective capture channel can be provided even in an inclined condition.

The invention relates to the technical field of medical instruments, in particular to a tissue tray assembly used in an abdominal surgery, which comprises a tray and a traction device, and is characterized in that the tray comprises a tray body and a plurality of support pieces, and the plurality of support pieces are of a scattered structure distributed on the tray body; the supporting pieces are divided into first supporting pieces and second supporting pieces, and the first supporting pieces and the second supporting pieces are distributed in a staggered mode. The supporting piece comprises a sleeve body and a telescopic rod, the telescopic rod is connected with an air pipe, and the amount of air in the telescopic rod is changed by injecting air into or exhausting air from the air pipe, so that the telescopic rod is extended or shortened; the telescopic rod corresponding to the first supporting piece and the telescopic rod corresponding to the second supporting piece are independent in motion form. According to the tissue tray assembly used in the abdominal cavity operation, the situation that tissue in the abdominal cavity is pressed for a long time can be avoided, the situation that blood vessels in the tissue are pressed for a long time is avoided, and the situation that the supported part on the tissue is insufficient in blood supply or ischemia or hypoxia occurs is avoided.

The invention relates to the technical field of medical instruments, and provides a steep pulse-based ablation system and method for liver cancer cells, and the system comprises a tumor feature recognition module which is used for obtaining imaging images of the liver cancer cells and recognizing tumor features, blood supply conditions and tumor centers of the liver cancer cells; the electrode inlet setting module is used for setting a safety boundary of liver cancer cells and setting an ablation area and a focus skin surface of the liver cancer cells based on the safety boundary and tumor characteristics; the ablation effect analysis module is used for calculating the electrode depth and the electrode angle of the liver cancer cells and analyzing the coverage effect of an ablation area; the electric field intensity identification module is used for analyzing cell membrane characteristics of the hepatoma cells, identifying the electroporation effect of the hepatoma cells and identifying the electric field intensity of the hepatoma cells; and the steep pulse ablation module is used for performing ablation treatment on the liver cancer cells in combination with the electric field intensity and a pulse generator to obtain an ablation result. The invention aims to avoid heat injury of surrounding tissues and improve the ablation effect of liver cancer cells.

A patella fracture fixation system includes a peripheral rim bone plate that is configured to be implanted along a parapatellar lateral approach. The bone plate can configured to minimize disruption of blood supply to the patella. The bone plate can be augmented with a Krackow suture pattern to assist in stabilization of a comminuted inferior pole.

The invention provides application of active decapeptide in preparation of a medicine for preventing or treating cerebral apoplexy, and belongs to the technical field of biological medicine, the active decapeptide with the amino acid sequence as shown in SEQ ID NO.1 is applied to prevention or treatment of cerebral apoplexy for the first time, the active decapeptide can effectively inhibit formation of cerebral thrombosis of zebra fish with ischemic cerebral apoplexy, and the active decapeptide can be used for preventing or treating cerebral apoplexy. The brain blood flow supply is recovered; meanwhile, the active decapeptide can significantly reduce the hemorrhagic area and hemorrhagic rate of the zebra fish brain with hemorrhagic stroke, repair brain vascular injury and inhibit the occurrence and development of hemorrhagic stroke. In addition, the active decapeptide has small toxic and side effects, and is of great significance for improving the clinical curative effect of cerebral apoplexy and reducing the medication risk when being used for research and development of novel drugs for resisting cerebral apoplexy.

The invention discloses a bone cement propelling device, and relates to the technical field of medical instruments. The two ends of the pipe body structure are a propelling section and a front end respectively, and a hole is formed in the side wall of the front end to form an outlet; and the push rod acts to enable the contents in the pipe body structure to flow out from the outlet. Bone cement can be injected and distributed in a stress concentration area where the end plate is in contact with the fusion cage, a bone grafting area in the middle of the fusion cage is avoided, and therefore the purpose of balancing end plate strengthening and blood supply is achieved. According to the bone cement injection device, the number of bone cement outlets and the injection position can be adjusted through relative rotation of the outer pipe and the inner pipe, and the first injection hole structure and the second injection hole structure are selectively aligned through rotation between the outer pipe and the inner pipe; therefore, at least one outlet or a combination form of two or more outlets can be formed in the tube body structure, the injection position and the injection amount of bone cement can be adjusted according to actual treatment work, and the functions of fixed-point injection and quantitative injection are achieved.

The invention relates to the technical field of medical image processing, in particular to a pulmonary blood vessel perfusion analysis method based on drainage basin dynamics, which comprises the following steps: acquiring a pulmonary artery blood vessel tree and a pulmonary artery CT film; extracting the pulmonary artery blood vessel tree based on the pulmonary artery blood vessel tree and the pulmonary artery CT film; based on the pulmonary artery blood vessel tree, pressure gradient fields in the pulmonary artery blood vessel tree and on the wall of the pulmonary artery blood vessel tree are calculated; extracting a pulmonary vein basin based on the pressure gradient field; based on the pulmonary vein drainage basin, perfusion analysis is achieved in combination with dynamic hemodynamic simulation; on the basis of perfusion analysis results, lung tissue blood supply conditions are evaluated, a multi-stage connected domain detection method is adopted, the method can more accurately extract a complex pulmonary artery blood vessel tree structure, the actual distribution condition of blood flow can be more truly reflected on the basis of a pressure gradient field drainage basin division method, and dynamic blood flow simulation is introduced, so that the dynamic blood flow simulation effect is improved. By means of the method, perfusion changes in the breathing process can be comprehensively captured, and more comprehensive diagnosis information is provided.

The invention discloses a composition for removing couperose skin and improving skin barrier and application of the composition, and belongs to the field of daily necessities. Through the combined action of the components, when the composition acts on couperose skin, a cold sensor in the skin can be effectively activated, a heat sensor in the skin can be effectively inhibited, the burning feeling of the skin can be relieved, capillary microcirculation can be promoted, clogging can be dredged, the couperose skin phenomenon can be improved, meanwhile, the skin barrier can be repaired, the skin tolerance can be improved, and the skin care effect can be achieved. The wrinkle phenomenon of the skin caused by insufficient blood supply of blood capillaries is improved.

The invention relates to the technical field of blood inventory management, in particular to a radio frequency tag reuse method and system for blood inventory management. Comprising the following steps that blood is collected, radio frequency tags corresponding to carriers are distributed, information of the radio frequency tags is read, the blood is put in storage, different kinds of blood are recorded and stored in the corresponding carriers, and rechecking is conducted through the number of the empty carriers; the blood storage information is acquired, the blood information is classified, the ex-warehouse quantity of blood of different blood types every day is acquired, and the blood demand quantity of different blood types is predicted, the demand quantity is predicted based on the ex-warehouse quantity, blood sampling and stock adjustment strategies can be planned in advance, blood shortage or excess is avoided, scientific classification and fine management of blood are achieved, and the blood quality is improved. The clinical blood use requirement is better met, the real-time stocktaking and alarming functions can remind workers to supplement insufficient blood types in time, and the timeliness and stability of blood supply are ensured.

The invention discloses a method for promoting diabetic fracture healing by using bone marrow mesenchymal stem cell exosomes, which comprises the following steps: separating MSCs (mesenchymal stem cells) from the bone marrow of a diabetic patient, culturing and extracting the exosomes; the method comprises the following steps: extracting an exosome from a bone fracture part, performing quantitative analysis on the extracted exosome, injecting the exosome into the bone fracture part in a manner of intravenous injection, local injection or minimally invasive injection, continuously treating, promoting proliferation and differentiation of osteoblasts by miRNA or mRNA in the exosome through targeting cells, enhancing angiogenesis, and further accelerating fracture healing. According to the exosome, proliferation and differentiation of osteoblasts are promoted through miRNA or mRNA in the exosome, the synthesis capacity of bone matrixes of the osteoblasts is enhanced, so that fracture healing is accelerated, meanwhile, the exosome provides necessary blood supply for fracture healing by adjusting vascular endothelial cells and promoting angiogenesis, and the repair capacity of fracture parts is effectively improved.

The invention belongs to the field of medical equipment. The artificial pneumatic auxiliary urination system comprises a bladder wrapping piece, and the bladder wrapping piece comprises a curved surface front shell and a curved surface rear shell; the end face of the curved-surface front shell and the end face of the curved-surface rear shell are in butt joint connection. A ureter wrapping shell is arranged on the curved-surface rear shell, a ureter outer hole and a ureter inner hole are formed in the ureter wrapping shell, and a ureter penetrates through the ureter outer hole and the ureter inner hole to enter the curved-surface rear shell; a bladder neck hole; an inner layer is arranged on the inner side of the curved surface front shell, is made of a flexible telescopic material and is connected with the inner side of the curved surface front shell close to the edge, a sealed cavity is formed between the inner layer and the curved surface front shell, the curved surface front shell is provided with a communicating piece, the sealed cavity is filled with a medium, the pressure intensity is increased, and the inner layer is extruded; the bladder wrapping piece is of a module assembly type, a hole and a groove are reserved in a wrapping shell, blood supply of the bladder and smoothness of a ureter and a neck opening of the bladder are guaranteed while the bladder is tightly wrapped, urine can be emptied easily, and bladder hernia is prevented from being formed.

The utility model relates to an intravascular stent, a stent system and a windowing area adjusting method, a stent body section is provided with a stent body inner cavity with two through ends, a branch window penetrating through the stent body inner cavity is formed in the side wall of the stent body section, and the branch window is located on the side wall of the first end of the stent body section and formed to the end side of the first end of the stent body section; the pipe body section is provided with a pipe body inner cavity with two through ends, and one end part of the pipe body section is connected with the second end part of the frame body section, so that the pipe body inner cavity is communicated with the frame body inner cavity. The branch windows of the two intravascular stents can be spliced into a complete closed window, and the overlapped length of the two intravascular stents can be adjusted to adapt to the actual sizes of the three branches on the arch to construct a windowing area with a proper size, so that the blood supply of the three branches on the arch is ensured. When the stent is used for interventional operation, in-vitro windowing or in-situ windowing is not needed, and when the stent is used for open operation, the number of anastomotic stomas can be reduced, the circulation stopping time can be shortened, and meanwhile the three-branch anatomical structure on the arch can be reserved. Therefore, the existing operation requirements are met.

The invention discloses an application of nitro fatty acid in preparation of a product for predicting, preventing and improving adverse cardiovascular events of patients with acute coronary syndrome. The invention provides application of nitro fatty acid in preparation of products for preventing and improving adverse cardiovascular events of ACS patients. According to the application, for the ACS patient, when the concentration of the 12-nitro conjugated linoleic acid in the body is larger than 0.196 ng / ml and the concentration of the 9-nitro conjugated linoleic acid is larger than 0.296 ng / ml, it is judged that the risk that the ACS patient is re-hospitalized and dead due to non-fatal myocardial infarction / unstable angina pectoris / blood supply reconstruction is low. By detecting the content of nitro fatty acid in a biological sample and supplementing nitro fatty acid, the occurrence rate of adverse events can be greatly reduced. Meanwhile, the invention further provides a detection method of nitro fatty acid, and the accuracy of biological sample detection is improved.

The invention relates to a blood protein peptide for promoting hair follicle reconstruction and application thereof, and belongs to the technical field of bioactive peptides. The blood protein peptide disclosed by the invention is selected from one or more of an MLL peptide fragment and a WDL peptide fragment; the amino acid sequence of the MLL peptide fragment is as follows: methionine-leucine-leucine; the amino acid sequence of the WDL peptide fragment is as follows: tryptophan-aspartic acid-leucine. The invention also provides a preparation method of the blood protein peptide and application of the blood protein peptide in hair follicle reconstruction. The blood protein peptide prepared by the technical scheme of the invention can obviously improve local blood supply around hair follicles, and has a wide application prospect in the field of treatment of alopecia.

The invention discloses a method, a device, equipment, a medium and a product for determining hemodynamic indexes of a blood circulation system under the action of an acceleration field, and relates to the technical field of hemodynamics, the method comprises the following steps: constructing a one-dimensional topological model and a 0-dimensional connection model of main artery and vein blood vessel networks, and assigning parameters to obtain a 0-1-dimensional coupling basic model; iteratively solving by combining the simplified model of the basic model, the objective function and the physiological measured data to obtain individualized model parameters of the subject, and assigning the individualized model parameters to the basic model; extracting geometric topology information of the blood vessel network of the concerned part based on iconography information and assigning the geometric topology information to a corresponding position of the 0-1-dimensional model; the acceleration equivalent to the real environment is applied, the individualized 0-1-dimensional model control equation of the subject is solved, the hemodynamic indexes of the blood circulation system under the action of the acceleration field are obtained, and the hemodynamic changes of the arteriovenous system and the blood supply conditions of all important organs of the subject under the action of the acceleration can be accurately and quantitatively evaluated.

The invention discloses an enhanced Swinin-Unet liver tumor segmentation method fusing blood vessel guidance and adaptive deformation attention. Through combination of elastic B-spline registration and affine transformation, nonlinear deformation is compensated, a multi-modal image space alignment error is reduced, and tumor boundary blur and feature dislocation are reduced. Topological features are extracted in combination with a blood vessel reconstruction module, and model attention is effectively guided. The encoder adopts a convolution pool and a deformable attention SADR down-sampling, and a lightweight deformable attention module is integrated through jump connection, so that effective multi-scale feature fusion and space alignment are realized, and the model perceptibility is enhanced. The graph theory model is embedded into liver lobe partition and blood vessel curvature constraint, and it is ensured that the segmentation result is strictly matched with blood vessel blood supply topology. In order to solve the class imbalance problem, an FA loss function is provided and combined with a structure correction algorithm (SGDR), so that incomplete segmentation and false positive artifacts are effectively reduced. Experimental verification on a LiTS data set shows that the method is superior to an existing method in liver and tumor segmentation, and Dice coefficients reach 93.38% and 91.39% respectively.