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5 results about "Bone cell" patented technology
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Bone cell' Bone cells', which are found within the bone tissue, are responsible for the make-up of the skeleton of vertebrates. They are made up of different bone cells: there is the compact tissue which is the hard outer part of the bone, the cancellous tissue which is all the spongy tissue inside of the compact tissue, and the subchondral tissue which is the smooth tissue at the end of each bone."All About Bone." All About Bone. Ohio State University, n.d. Web. 19 Mar. 2013. Bone cells all work together inside of the bones to help keep up the skeletal system. The bone cells do many things for the skeletal system such as the development of new bones, the maintenance of bones, and the regulation of minerals in the body. Types There are four main categories of bone cells which include: lining cells, which protect the boneOursler, Merry J., and Teresita Bellido Bellido. "B>one Cells." ASBMR Educational Materials. ASBMR Educational Materials, 12 Sept. 2003. Web. 19 March 2013. Osteoclasts Osteoclasts are very large multinucleate cells that are responsible for the breakdown of bones. The breakdown of bone is very important in bone health because it allows for bone remodeling.
A method for preparing and using strontium-doped magnesium-bioactive glass
The present application relates to the technical field of bioactive glass, in particular to a preparation method and application of strontium-magnesium-doped bioactive glass, on the basis of selecting suitable raw materials, the co-precipitation method is adopted, strontium element is doped, and magnesium oxide is compoundedly added, so that the prepared bioactive glass has regular properties, good dispersible spherical particles, faster and stronger hydroxyapatite formation capacity, faster ion release rate, and can release calcium, phosphorus and silicon ions in simulated body fluid, form more hydroxyapatite, promote the proliferation and stability of bone cells, and stimulate new bone formation. The strontium-magnesium-doped bioactive glass is used in cooperation with mineral trioxide aggregate (MTA), so that cell adhesion, expression of bioactive enzymes, activity of fibroblasts can be promoted, and the strontium-magnesium-doped bioactive glass can be applied to the repair of human bone and dental pulp tissue.
Owner:GUANGXI XINYE BIOLOGICAL TECH
A human malignant giant cell tumor of bone cell line and its use
The present application relates to the technical field of tumor biology, and specifically discloses a human malignant giant cell tumor of bone cell line and application thereof, the human malignant giant cell tumor of bone cell line is preserved on April 9, 2025, the preservation address is China Center for Type Culture Collection, located in Wuhan University in Wuhan, Hubei Province, and the preservation number is CCTCC NO:C202539.The human malignant giant cell tumor of bone cell line of the present application is from the tumor tissue after surgical resection of a Chinese malignant giant cell tumor of bone patient, and is suitable as cell material for developing malignant giant cell tumor of bone related immunotherapy, diagnosis and drug development.The cell line of the present application contains H3F3A G34W mutation, and has high sensitivity and specificity in the diagnosis of malignant giant cell tumor of bone.This cell line can be used as a tool cell for researching target drugs with H3F3A as a target, provides a cell model for Chinese malignant giant cell tumor of bone research, and provides an experimental platform for mechanism research of malignant giant cell tumor of bone.
Owner:THE SECOND AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY PLA
A skull flap resuscitation perfusion device
ActiveCN224268010UImprove survival rateImprove repair and cleaning efficiencyDead animal preservationFlap repairBone flap
This utility model discloses a cranial flap resuscitation and perfusion device, including a workbench with a platform plate fixedly connected to the top of the workbench; a perfusion mechanism is provided on the top of the platform plate, and a sealing component is provided inside the perfusion mechanism; wherein, the perfusion mechanism includes an insulated box fixedly installed on one side of the top of the platform plate, and an inner liner is embedded in the inner side of the insulated box, and a liquid addition pipe is fixedly connected between the top of the insulated box and the inner liner, thereby enabling precise control of the temperature, flow rate and pressure of the perfusion fluid, simulating the human physiological environment, providing good resuscitation conditions for the isolated cranial flap, effectively maintaining the activity of cranial flap bone cells, improving the survival rate of cranial flap after reimplantation, reducing the incidence of postoperative complications such as bone flap necrosis and infection, greatly improving the efficiency of cranial flap repair and cleaning, and reducing the workload of staff.
Owner:HENAN TISSUE CELL BANK CO LTD
Split fusion device and method of manufacturing same
This invention provides a split-type fusion device and its manufacturing method. The split-type fusion device includes two independent fusion bodies configured to abut each other when implanted in the body. Each fusion body includes a conductive layer disposed on the side facing the other fusion body, and the fusion body is filled with a piezoelectric elastic material. The conductive layer is electrically connected to the elastic material. This split-type fusion device, by setting two independent, abuttable fusion bodies filled with piezoelectric elastic material and a conductive layer on the abutment surface of the fusion bodies, allows the microcurrent generated by the piezoelectric elastic material to be transmitted through the conductive layer, accelerating bone cell proliferation and differentiation and improving bone fusion efficiency. Simultaneously, the conductive layer guides bone cells to grow directionally at the abutment surface, promoting the gradual separation of the two fusion bodies and achieving adaptive intervertebral height adjustment in vivo. This allows height adjustment and bone fusion to be completed synchronously, solving the problem of the difficulty in simultaneously achieving both.
Owner:SUZHOU & SCI & TECH DEV
Demineralized bone paper
PendingUS20260144913A1Bioreactor/fermenter combinationsBiological substance pretreatmentsTissue GraftingAssay
Disclosed herein are three-dimensional bone tissue grafts produced from stacked demineralized bone paper. Also disclosed are methods for treating a subject using tissue grafts produced from the disclosed demineralized bone paper. Also disclosed are assay systems that involves culturing bone-promoting cells on the disclosed demineralized bone paper.
Owner:UNIV OF MASSACHUSETTS