1323 results about "Target site" patented technology

The invention discloses an optical storage charging station cross-site heterogeneous data fusion health state early warning method, which adopts transfer learning and domain adaptation technologies, measures the data distribution difference between a source site and a target site through the maximum mean value difference, realizes knowledge transfer and improves the generalization ability of a model. And on the basis of an Attention-LSTM feature fusion mechanism, feature weights are adaptively allocated, and the fault feature extraction capability is enhanced. And designing a fault mode sharing module, coding the fault mode of the source site into a knowledge base, and rapidly matching similar faults of the target site. A model compression technology is introduced, lightweight deployment is realized through knowledge distillation and a parameter quantification method, and operation of edge equipment is effectively supported. And furthermore, an online learning mechanism is adopted to dynamically update model parameters to ensure that the model adapts to the environment change of the target site. According to the method, the accuracy and robustness of cross-site fault prediction are remarkably improved, the model deployment time is shortened, and the method is widely applied to intelligent operation and maintenance of the optical storage charging and discharging integrated power station.

The invention discloses a garden landscape design method based on digital twinning, and belongs to the technical field of landscape garden design. According to the method, a target site environment data set is collected, and a site thermodynamic distribution cloud picture is generated through a geographic space grid processing unit; extracting a site space pattern feature matrix on the basis; constructing a landscape effect distribution model, decomposing the feature matrix into topographic relief, seasonal phase color and illumination reflection parameters, driving the model to generate a three-dimensional scene rendering sequence, embedding the model into a three-dimensional digital twin scene of the garden site, and associating the parameters with physical attributes of the twin scene in real time; dynamic optimization of the landscape scheme is executed, an element replacement instruction is generated, and the spatial topological relation network is updated; and outputting a site design scheme map, adjusting facility layout coordinates, and generating a final scheme data packet in combination with the path connectivity, so that the precision and adaptability of garden landscape design can be improved.

The invention relates to an improved NSGA-III-based multi-target geographic site selection optimization method and system, belongs to the technical field of optimization in business management and resource planning, and particularly relates to resource allocation and site selection decision making by using a calculation model. The technology aims to solve the problems of slow scheme convergence, non-uniform solution set distribution and low calculation efficiency when multi-target site selection is carried out under limited resources. According to the scheme, geographic space data is preprocessed, and an initial population representing different site selection schemes is generated; carrying out optimization iteration by adopting an improved NSGA-III algorithm, and calculating a plurality of objective functions such as coverage rate, normalized population density and medical service accessibility; and performing individual selection and population updating by utilizing improved reference point generation and vertical distance measurement. The method is mainly used for improving the efficiency and effect of commercial and municipal decisions such as urban planning, medical resource configuration, energy station layout and logistics network optimization.

Surgical systems and methods for tracking physical objects near a target site during a surgical procedure are provided, the surgical system employs a navigation system and a surgical instrument; an instrument tracker is provided on the surgical instrument and a patient tracker is provided on the patient's target tissue; the system and method is configured to detect an error condition compromising accuracy of the navigation guidance and to track and monitor a tool-to-bone offset.

Provided herein are systems, compositions, and methods for generating immunogenic peptides or epitopes from tumor associated antigens (e.g., in vivo or ex vivo). Polynucleotides (e.g., genes) encoding the tumor associated antigens may be edited at selected target sites by nucleobase editors comprising a catalytically-inactive Cas9 and a cytosine deaminase, leading to the expression of heteroclitic or cryptic peptides that are more immunogenic than the native peptide derived from the tumor associated antigens. The heteroclitic or cryptic peptide elicit strong tumor-specific immune response (e.g., T-cell response or B-cell response), which inhibits tumor growth and metastasis.

The invention relates to the field of field engineering characteristic evaluation, in particular to a fracture characteristic calculation method based on resistivity tomography and resistivity static sounding. The method comprises the steps that firstly, in-situ site resistivity parameter calibration is carried out through a resistivity static sounding (RCPTU) test technology, and a resistivity index background value of a target site is obtained; then, acquiring an initial value of the electrical resistivity of the whole area of the target site by adopting a three-dimensional electrical resistivity tomography (ERT) technology; and finally, according to the resistivity-fracture inversion model, identifying the fracture distribution condition of the whole region of the target site, and giving a fracture rate evaluation model of the target site. According to the method, the precision problem of single in-situ test equipment is solved, the test precision of site three-dimensional resistivity parameters is improved, the reliability of three-dimensional inversion calculation is improved, and the three-dimensional space distribution of the soil body fractures can be evaluated quickly, nondestructively and accurately.

Provided is a program, etc. capable of acquiring information related to an amount of body tissue from an X-ray image with high accuracy using a small number of cases. A computer acquires training data including an X-ray image of a target site and information related to an amount of body tissue obtained from a CT (Computed Tomography) image of the target site. The computer generates a learning model configured to output information related to an amount of body tissue of a target site in an X-ray image when the X-ray image is input using acquired training data.

Methods of treating a nerve injury are disclosed. The methods include administering to a target site of the nerve injury a thermally stable preparation having a purified amphiphilic peptide in an aqueous biocompatible solution, being configured to self-assemble into a hydrogel, and administering to the target site a buffer having an effective amount of an ionic salt and a biological buffering agent to form the hydrogel. The methods include administering to the target site a biological material suspension in an amount effective to treat the nerve injury. The methods include administering to the target site an anti-scarring agent in an amount effective to treat the nerve injury. The target site is associated with central nervous system tissue or peripheral nervous system tissue. The nerve injury includes spinal cord injury and peripheral nerve injury.

The invention discloses a flow feature confusion method based on an AI virtual human, and the method comprises the steps: S1, configuring the basic attributes of the virtual human and a preset behavior strategy, and automatically obtaining the fingerprints of Internet access equipment of a user; s2, virtual human environment fingerprint camouflage is carried out by configuring a containerized operation environment and adjusting browser fingerprints; s3, dynamically generating behavior parameters for determining a virtual human online task based on LLM drive of preset parameters; and S4, the virtual human calls a local browser driver on line based on the behavior parameters obtained in the S3, simulates human to access the target site and generates feature traffic. According to the method, the virtual human Agent is driven by the AI, the mixed flow is generated by autonomously acting on the network, the user identification and tracking technology of the network access target based on the flow signal characteristics is effectively interfered, the signal statistics characteristics of the user internet surfing flow can be effectively mixed, and the method is suitable for the network privacy protection requirements in various scenes.

The invention discloses a highway accident scene sensing system based on AI identification and unmanned aerial vehicle cooperation, and relates to the technical field of intelligent traffic. Comprising a central planning node for fusing geographic information, meteorological information and road obstacle information of a target site with the real-time state of an unmanned aerial vehicle, constructing a digital twin scene model, generating an initial four-dimensional collaborative awareness route plan, and dividing sub-airspaces; the distributed airborne intelligent agent obtains peripheral multi-source data of the unmanned aerial vehicle, constructs a surrounding environment real-time situation map through an AI recognition algorithm, and determines a flight instruction of the unmanned aerial vehicle according to the surrounding environment real-time situation map and the divided sub-airspace; and the reconfigurable intelligent metasurface is used for adjusting surface electromagnetic characteristics according to the divided sub-airspaces and sending directional beams to the unmanned aerial vehicle. Therefore, the problems of cooperative scheduling, obstacle avoidance and communication guarantee of multiple unmanned aerial vehicles in a complex accident scene are effectively solved, and the efficiency and safety of emergency disposal are remarkably improved.

An ultrasonic surgical device comprising of a proximal end and a distal end to be used in a robotic surgical system. The distal end comprises of a first jaw with an ultrasound transducer array and a second jaw with either a reflecting surface or an ultrasound transducer array. The distal end is configured to grasp a blood vessel or a living tissue. The proximal end is configured to apply a drive signal to the ultrasound transducer array. A plurality of rotary joints is connected at the distal end to facilitate its articulation. The ultrasound transducer array, generates acoustic vibrations in the grasped blood vessel, or living tissue, based on the applied drive signal by a control system of the robotic surgical system. The ultrasound transducer array, is configured to sense parameters of a target site on a grasped blood vessel or living tissue, based on the reflected acoustic vibrations.

The invention relates to the technical field of wind generating sets, and discloses a trench excavation and cable laying method which is applied to the wind generating sets, cables comprise cables and optical cables, and the method comprises the steps that according to a preset construction drawing, preparation of target construction equipment and target construction tools is completed, measurement is carried out on a target site, and a target path is obtained; according to the target path, excavation of the target groove is completed according to the target specification of the target groove in the construction drawing; determining the length of a target cable according to the type, the target path and the target specification of each piece of target electrical equipment in the target wind generating set, and determining the laying mode and laying matters needing attention of the target cable according to the soil texture condition of the target groove and the type of the target electrical equipment; and cable laying is carried out, the target construction image is monitored by using the hazard source identification model in the laying process, and early warning is carried out when a target hidden danger is monitored. The cable laying device has the effects of improving the cable laying efficiency and reducing the cable laying cost.

Novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation are described herein. Methods and devices disclosed herein utilize a synergistic combination of two or more antiseptic agents to reduce contact time, enhance antimicrobial effects, and reduce the likelihood of allergy and other side effects from the antiseptic agents in subjects. In one embodiment, devices include a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

The invention relates to a site micro-vibration attenuation test measuring point determination method and system, belongs to the technical field of vibration test, and solves the problem that vibration test measuring point arrangement depends on vibration source load accuracy or artificial experience in the prior art. The method comprises the following steps: determining a basic measuring point based on a target site parameter, obtaining an actual measurement vibration response, and calculating an actual measurement response transfer ratio; establishing an initial finite element model of the target site, and applying a preset load to the initial finite element model to obtain an initial finite element calculation result; according to the basic measuring points, corresponding model calculation points and predicted vibration responses are extracted, and predicted response transfer ratios are calculated; and performing model parameter updating by using the actually measured response transfer ratio and the predicted response transfer ratio, obtaining a basic finite element model, generating a vibration transfer form curve, obtaining vibration transfer characteristics, and determining the number and the positions of the measuring points. The micro-vibration transmission characteristics are accurately determined without depending on the vibration source load, and the number and the positions of the vibration attenuation test points are reasonably formulated.

The invention discloses an MEP automatic measurement and threshold discrimination method and system based on a mechanical arm. The MEP automatic measurement and threshold discrimination method comprises the following steps: constructing a scalp hotspot probability distribution map based on a brain map; dividing the hotspot scalp map into a plurality of sub-regions, and selecting candidate points from the plurality of sub-regions to obtain a candidate scalp stimulation point list; carrying out transcranial magnetic stimulation according to a point position sequence of the candidate scalp stimulation point list, simultaneously collecting a motor evoked potential signal triggered by each stimulation, and simultaneously collecting a motor evoked potential signal triggered by each stimulation; preprocessing and feature extraction are carried out on the collected motor evoked potential signals, whether stimulation evokes effective MEP response or not is judged through a response judgment method, and a candidate point-MEP response database is formed; screening an optimal motion hotspot point location in the candidate area, and taking the optimal motion hotspot point location as a target site; and searching an individualized resting motion threshold value on the optimal motion hotspot point location.

A method for performing automatic brightness control may include receiving an image of a target site from an imaging system of a medical device, and identifying a region of interest in the image. The region of interest may include a physical feature in the target site identified in the image. The method may further include determining a current image brightness value for the identified region of interest, and adjusting one or more operating parameters of the imaging system based on the current image brightness value and a target image brightness value.

The invention is applicable to the technical field of rabbit breeding, and provides a method for increasing the body weight of a rabbit based on a gene editing technology, which comprises the following steps: designing an action target sgRNA on a rabbit NR6A1 gene aiming at an NR6A1 p.P192S site; uniformly mixing the synthesized sgRNA and SpRY-CBE, injecting fertilized eggs, transplanting the fertilized eggs into fallopian tubes of receptor female rabbits, and feeding the receptor female rabbits until production; dNA is extracted from produced young rabbit ear tissues, PCR and sequencing are carried out, and if C at the fifth site in NR6A1 gene target sites is mutated into T, it is proved that single base mutation is obtained, and the NR6A1 gene edited rabbit is obtained. According to the invention, the rabbit variety with increased weight is successfully cultivated; a new thought of animal genetic breeding is developed by utilizing a gene editing technology, the method has application values in promoting improvement of genetic characters of rabbits and improving production performance and economic value of the rabbits, and powerful support is provided for high-quality development of the animal breeding industry in China.

A laser can be controlled based on different tissue compositions, such as in real time. After a first time period, a first composition of a in vivo target site can be identified. Based on the first composition, a plurality of lasers can be controlled to emit light at a first wavelength where controlling includes activating a first combination of the plurality of lasers. After a second time period, a second composition of the in vivo target site different from the first composition can be identified. Based on the second composition, a plurality of lasers can be controlled to emit light at a second wavelength, such as can include activating a second combination of the plurality of lasers. The first combination of the plurality of lasers can be different from the second combination of the plurality of lasers.

The invention discloses a collaborative operation system and method for a humanoid robot and a robot dog. The system comprises a server, the humanoid robot and the robot dog. The server, the humanoid robot and the robot dog are interconnected through a hybrid communication network; the server receives a task request sent by an external system; creating a task execution instruction of the humanoid robot and a task search instruction of the robot dog; sending a task execution instruction to the humanoid robot, and sending a task search instruction and parameters carried by the task request to the robot dog; the robot dog responds to the task search instruction and carries out traversal search on a target site corresponding to the operation map; sending the searched to-be-processed object information and self operation parameters to the humanoid robot; and the humanoid robot responds to the task execution instruction and performs operation on the target site based on the to-be-processed object information shared by the robot dog. By adopting the embodiment of the invention, the collaborative operation of the humanoid robot and the robot dog can be realized, and the task execution efficiency is improved.

【Solution means】The proxy device includes a request determination unit 105 that receives a request sent from a virtual browser and determines the security risk of the request URL specified in the request, and a request transfer unit 101 that transfers a request determined to be normal by the request determination unit 105 to a server 30 that operates the site to be analyzed, where the site to be analyzed is a target site where the service used on the site to be analyzed is specified, a response analysis unit 102 that receives and analyzes a response from the server 30, and a response return unit 103 that returns the response to the virtual browser. According to this, it is possible to prevent the analysis device 10 from receiving a response having a security risk.

The invention relates to the field of nucleic acid editing, in particular to the technical field of regularly clustered interval short palindromic repeat (CRISPR). In particular, the invention relates to a mutant of a Cas effector protein, a fusion protein comprising the mutant, and nucleic acid molecules encoding the same. The invention also relates to complexes and compositions for nucleic acid editing (e.g., gene or genome editing). The invention also relates to methods for nucleic acid editing (e.g., gene or genome editing) using the proteins or fusion proteins comprising the invention. Compared with a wild type Cas protein, the Cas protein mutant disclosed by the invention has better activity, such as higher cleavage activity, stronger target site recognition capability and higher target sequence editing activity.

The invention discloses a distributed energy storage device data acquisition method, system, device and medium, and relates to the field of energy storage data acquisition, the method comprises the following steps: a cloud platform sends an acquisition instruction to an acquisition terminal in response to received registration information of a target energy storage device; the acquisition terminal responds to a received acquisition instruction, sends a detection frame through a physical port according to a target communication protocol, establishes communication with target energy storage equipment, acquires identification information of the target energy storage equipment, determines a target point location table from a local point location library according to the identification information of the target energy storage equipment, and acquires the target energy storage equipment according to a target acquisition strategy; and obtaining original operation data of the target energy storage equipment, and obtaining target structured data according to the target point location table and the original operation data. The problems of poor compatibility and low expansibility in the prior art can be solved, and the collection efficiency of the energy storage data is improved.

The invention provides a radiotherapy plan generation method and device, equipment and a medium, and the method comprises the steps: obtaining a target function image of a target object; the target function image comprises a target region, an organ at risk and a target part; determining target dose information of the target part based on the target function image, the target function partitioning result, the target region segmentation result and the endangered organ segmentation result; the target function partitioning result is used for indicating spatial distribution of a plurality of functional regions of the target part divided according to the functional state, and the target dose information comprises doses of different regions of the target part; and generating a radiotherapy plan based on the target dose information. By applying the embodiment of the invention, the set dose information of the target part is more reasonable, so that the radiotherapy plan generated based on the target dose information can ensure the accuracy of tumor control, reduce the risk of radioactive injury and realize targeted protection of the target part.

The present disclosure provides compositions and methods for prime editing with improved editing efficiency and / or reduced indel formation by inhibiting the DNA mismatch repair path way while conducting prime editing of a target site. Accordingly, the present disclosure provides a method for editing a nucleic acid molecule by prime editing that involves contacting a nucleic acid molecule with a prime editor, a pegRNA, and an inhibitor of the DNA mismatch repair pathway, thereby installing one or more modifications to the nucleic acid molecule at a target site with increased editing efficiency and / or lower indel formation. The present disclosure further provides polynucleotides for editing a DNA target site by prime editing comprising a nucleic acid sequence encoding a napDNAbp, a polymerase, and an inhibitor of the DNA mismatch repair pathway, wherein the napDNAbp and polymerase is capable in the presence of a pegRNA of installing one or more modifications in the DNA target site with increased editing efficiency and / or lower indel formation. The disclosure further provides, vectors, cells, and kits comprising the compositions and polynucleotides of the disclosure. The present disclosure also provides compositions and methods for prime editing with improved editing efficiency and / or reduced indel formation with modified prime editor fusion proteins. The disclosure further provides, vectors, cells, and kits comprising the compositions and polynucleotides of the disclosure.

Antisense oligomer conjugates complementary to a selected target site in the human dystrophin gene to induce exon 45 skipping are described.

The invention discloses a fan site selection method and system based on different-mode nested grids, and belongs to the technical field of fan site selection, and the method comprises the steps: firstly constructing a large-region sea ice background field by using global data to preliminarily screen candidate regions, then constructing a small-region high-resolution background field through a grid nesting technology, and carrying out the dynamic simulation, according to the method, a sea ice evolution field is obtained, an initial field is corrected by fusing field and satellite data, errors are quantized, comprehensive scoring is carried out to screen target site selection, finally, simulation parameters are dynamically optimized according to actually measured data, and a final site selection is determined through iterative correction. According to the method, multi-scale evaluation from macroscopic preliminary screening to microcosmic fine screening is realized, and through data fusion and dynamic optimization, the precision and reliability of fan site selection in a complex sea ice environment are remarkably improved.

Disclosed herein is a system for treating skin and / or nails with cold plasma. The system includes a discharge device, which includes a handle and an applicator mounted thereon, and control infrastructure, which includes a waveform generator. The applicator includes an elongated tube housing therein a cathode. The handle includes a flyback amplifier. The waveform generator is configured to induce the flyback amplifier to establish a voltage at the cathode. The voltage produced by the flyback amplifier is configured to generate a self-sustaining Townsend avalanche when a distal end of the tube is positioned sufficiently near a target site on a skin surface or a nail of a subject, such that a cold plasma discharge is produced and directed at the target site and having an average power between about 0.1 μW and about 10 μW, so that the target site is not heated.

The invention provides a desert steppe area mining area gangue discharge field ecological vegetation screening method and system, and the method comprises the steps: determining the classification factors of the site types of topographic regions based on site attribute information, and dividing a plurality of topographic regions into a plurality of different site types; identifying vegetation state information on the terrain area of the target site type to obtain a vegetation mode; calculating an evaluation score of the vegetation mode based on the vegetation type related to the vegetation mode; optimizing the vegetation mode to obtain a target vegetation type on the basis of correlation features among various types of vegetation in the vegetation mode; the method comprises the following steps: determining classification factors of site types according to real area information, dividing a waste rock discharge field into multiple types, determining vegetation modes based on vegetation states of the site types, calculating evaluation scores of the vegetation modes, and further optimizing the vegetation modes to obtain optimal vegetation types of the site types. Thus, vegetation types adapted to various site types are generated to obtain a stable and effective ecosystem.

The disclosure generally provides for a surgical system comprising an imaging device including a gantry supported for translation between a first position and a second position to obtain imaging data of a target site of a patient over a scan period, and a position sensor to generate gantry data representing a position of the gantry relative to the base between the first position and the second position; trackers including a gantry tracker operatively attached to the gantry; a navigation system including a localizer to track states of the trackers in a navigation reference frame; a controller operatively connected to the imaging device and the navigation system, and configured to register the imaging data to the navigation reference frame by synchronizing the gantry data generated by the position sensor with changes in tracked states of the gantry tracker occurring over the scan period representing movement between the first and second position.

To provide an analysis system and an analysis apparatus, based on the analysis results of access status to a website, which can obtain proposal information on effective measures to improve the access status to the website.SOLUTION: An analysis apparatus comprises: a prompt generation unit 11 for generating a prompt including intrusions for suggesting ways to improve access status and reference information using information describing the contents of a website as an analysis target, report information of analysis results related to access status to the target site, information describing the contents of one or more services utilizable for the improvement of the access status and a template for prompt generation; and an analysis unit 12 for acquiring proposal information on measures to improve the access status to the target site from an LLM 30 utilizing services by inputting the generated prompt into the LLM 30. With this configuration, the proposal information of the measures in consideration of the site content information and the service content information can be obtained.SELECTED DRAWING: Figure 2