95 results about "Periosteum" patented technology

The invention provides a periosteum distraction system and a using method thereof, the periosteum distraction system comprises a periosteum distraction plate, a primary nail and a secondary nail, the periosteum distraction plate comprises a first distraction plate and a second distraction plate, and the first distraction plate and the second distraction plate are detachably connected; the periosteum distraction plate is provided with a first connecting part, the female nail is provided with a second connecting part, and the first connecting part is fixedly connected with the second connecting part; the female screw is of a hollow structure and is provided with an internal thread; the son nail is mounted in the mother nail, the son nail is provided with an external thread, and the external thread is matched with the internal thread of the mother nail; the son nail is rotated to enable the mother nail and the periosteum distraction plate to move in the axial direction of the son nail, and the end of the son nail protrudes out of the periosteum distraction plate. By using the technical scheme provided by the invention, the periosteum incision is smaller, the trauma to the periosteum is smaller, and the condition that the skin is stimulated when the periosteum is stretched is reduced.

The invention relates to a method for constructing an injectable bone organ to realize rapid bone regeneration. The method comprises the following steps: 1, obtaining a water-soluble periosteum acellular matrix by adopting an acellular technology; secondly, compound bone salt is prepared according to the proportion of natural bone salt components, the water-soluble periosteum acellular matrix and the compound bone salt are mixed according to the proportion of natural bone organic and inorganic components to form a bionic matrix component, and then the bionic matrix component is added into gelatin to construct a completely bionic osteogenesis microenvironment; and 3, constructing a bone regeneration material to form a bone organ, firstly preparing a granular gelatin scaffold with a full-bionic osteogenesis microenvironment, then inoculating the bone marrow mesenchymal stem cells, finally performing in-vitro culture, and regulating the differentiation and secretion of the bone marrow mesenchymal stem cells by virtue of the osteogenesis microenvironment of the scaffold to finally form the bone organ.

The invention relates to an artificial periosteum suitable for a complex bone surface. The artificial periosteum is an integrated single-layer membrane. The artificial periosteum is provided with an anti-adhesion area, a directional pore channel structure area and a bone contact area which are sequentially distributed in the thickness direction. The directional pore channels are sequentially filled with composite hydrogel for filling bone surface pores and promoting bone repair and bonding gel for bonding bone surfaces in the extending direction of the directional pore channels; an expanding agent and prestretching memory polymer fibers are dispersed in a matrix of the artificial periosteum; the expanding agent is enriched in the matrix of the directional pore channel structure area and the bone contact area and is used for driving the composite hydrogel to leave the directional pore channel so as to seal bone surface gaps or cracks; and the pre-stretched memory polymer fibers are enriched in the matrix of the anti-adhesion area and are used for limiting the expansion direction of the expanding agent. The artificial periosteum can solve the technical problems that in the prior art, the attaching effect of the artificial periosteum on the complex bone surface is poor, and the long-term reliability is poor.

The invention discloses a filling material for promoting tissue regeneration and a preparation method thereof. The filling material is prepared by using type II collagen as a microsphere wall material and hydroxyapatite as a core material and dispersing composite microspheres in type I collagen gel. The filling material for promoting tissue regeneration prepared by the invention is used for filling parts such as eyebrow lines, eyebrow subcutaneous support, zygomatic fat and cheek fat pads, lacrimal ducts, nasolabial folds, noses, lips, chin, mandible periosteum and the like, has an obvious mechanical support effect, continuously stimulates the formation and rearrangement of endogenous collagen on the basis of extrinsic collagen supply, and can be used for promoting tissue regeneration. The medical and aesthetic plastic requirements are met.

The application discloses a path planning method for subcutaneous deep layer injection of a mandible, which comprises the following steps: determining a target region of a subcutaneous deep layer which needs to be filled or improved in contour based on three-dimensional anatomical data of a mandible; the subcutaneous deep layer refers to a loose connective tissue gap between a subcutaneous fat layer and an upper periosteum layer; planning a main path which is substantially parallel to a baseline of a lower edge of the mandible or substantially coincides with a preset mandible contour line in the target region; the main path is located in the subcutaneous deep layer; planning a plurality of branch injection paths based on the main path; the starting points of the branch injection paths are distributed at intervals along the main path and extend alternately to the outside of both sides of the main path; and all the paths form a wheat ear-shaped topological structure with the main path as a central axis and the branch injection paths extending to both sides. The method effectively avoids excessive concentration of fillers in any dimension, thereby significantly reducing the swelling degree of local tissues caused by pressure concentration and being beneficial to shortening the recovery time.

The invention discloses an operation method for splitting an oral implant bone, which comprises the following steps of: preparing an ultrathin bone sheet of which the buccal side is less than 1mm, reserving physiological connection between periosteum and the bone sheet, and constructing a periosteum bone flap. The periosteum flap is of a natural barrier membrane structure, and integrates the function of a bone sheet rigid support and the semi-permeable membrane characteristic of the periosteum. The buccal ultrathin bone sheet is connected with the basal bone, is a rigid support structure, supports an osteogenesis space, and can provide bone marrow stroma cells to participate in bone defect repair. Physiological attachment of periosteum is not only a blood supply source of an inner side bone sheet, but also exerts the characteristics of a semi-permeable membrane, replaces an artificial barrier membrane to stop fiber tissue from growing in, and follows the PASS principle of the GBR technology, so that the operation risk is reduced, the use of the artificial barrier membrane is reduced, the adaptation disease of bone splitting is widened, the absorption of buccal side bones is reduced, and the bone splitting effect is improved. And the clinical effect of bone defect repair is improved.

The application discloses a jaw bone defect negative pressure repair body with a flushing function and a preserved periosteum, which comprises a base body, the base body is a titanium alloy net structure formed by 3D printing, two ends of the base body are adapted to be attached to bone broken ends, and an outer surface of the base body is adapted to be contacted with jaw bone periosteum, the base body is internally provided with a negative pressure suction pipeline penetrating through the base body, an outer pipe opening of the negative pressure suction pipeline is connectable to a negative pressure suction device, a pipe wall of the negative pressure suction pipeline is distributed with through holes formed by the titanium alloy net structure, and a reserved flushing pipeline is arranged around an outer periphery of the negative pressure suction pipeline, and the reserved flushing pipeline is distributed with flushing holes around the outer periphery. The repair body has the following functions: promoting growth and differentiation of osteoblasts on the surface of the bone broken ends and the periosteum, and promoting new bone formation; and being capable of discharging tissue exudates and the like out of the body.

The utility model relates to the field of oral implants, and discloses a Z-shaped subperiosteal implant, comprising a bracket, a front wing and a rear wing connected with the bracket, wherein the front wing, the rear wing and the bracket are three-dimensional structures that conform to the maxillary bone of a human body; the bracket is used to be attached to the surface of the maxillary bone, and a plurality of bases are arranged along the length direction of the bracket, and one end of the base away from the bracket penetrates into the gums for fixing the bracket; the front wing and the rear wing are respectively arranged on both sides of the bracket in the width direction, the front wing is used to be attached and fixed to the surface of the canine support of the maxilla, and the rear wing is located on the side of the greater palatine foramen close to the maxilla and is used to be attached and fixed to the palate side of the maxillary posterior teeth area and the surface of the palatine bone; the rear wing part is placed on the palate side of the maxillary posterior teeth area and the surface of the palatine bone, which can avoid performing a large flap operation on the buccal side, simplify and shorten the operation process, reduce the difficulty, make the operation simpler and safer, and can also reduce the pressure of the implant on the soft tissues on the lip and cheek sides, avoid the occurrence of soft tissue retreat, and reduce the probability of peri-implantitis.

The invention relates to the technical field of periosteal repair, and particularly discloses a suture anchor for periosteal cartilage defect repair and a using method thereof.The suture anchor comprises at least two anchor bodies, the head of each anchor body is a pointed cone part, and a suture blind hole is formed in the tail of each anchor body; at least one group of threading rods which are arranged at intervals with the bottoms of the threading blind holes are arranged in the threading blind holes; the at least one tail line penetrates through the threading blind hole of the anchor main body; and the anchor main body and the tail line are made of biocompatible materials. After the tail line is tightened, irreversible fixation is achieved through an automatic locking structure, postoperative tail line loosening or periosteum displacement is avoided, and the cartilage regeneration effect is improved.

Provided herein is a bone repair composition that is composed of periosteum containing an angiogenic growth factor(s), cancellous bone chips containing viable osteogenic cells, and, optionally, demineralized bone matrix (DBM) chips. Also provided herein are articles of manufacture and methods of use thereof to treat bone defects.

The application discloses a kind of biomimetic silk fibroin cartilage scaffolds for cranium defect repair, belong to biomedical engineering technical field.To solve the problem of single structure, low bone formation efficiency and mismatching of mechanical properties and degradation rate of existing cranium repair scaffold, the application provides a kind of scaffold, which includes in order from outside to inside: biomimetic periosteum layer, bone conduction and vascularization layer and cartilage induction layer.Biomimetic periosteum layer is dense nanofiber membrane structure, and plays the role of physical barrier and osteoinduction;Bone conduction and vascularization layer is gradient porous structure with gradually decreasing aperture from outside to inside, aiming to guide the ordered growth of blood vessels and cells, and promote rapid vascularization;Cartilage induction layer is sponge-like microporous structure, used for forming stable cartilage template and starting endochondral ossification.The application simulates the natural bone healing process through structural biomimicry and functional zoning, synergistically promotes vascularization and osteogenesis, and realizes efficient biological repair of cranium defect.

The invention provides a cerebral periosteum detacher for the neurosurgery department, and belongs to the technical field of medical instruments. Comprising a grab handle, connecting rods are fixedly connected to the two ends of the grab handle correspondingly, stripping mechanisms are arranged at the ends, away from the grab handle, of the connecting rods correspondingly, the two stripping mechanisms are different in size, annular grooves are formed in the surfaces of the connecting rods correspondingly, and air bags are connected to the interiors of the annular grooves in a surrounding mode; an air bag is arranged on the handle, a ventilation mechanism is arranged on the handle, the air conveying end of the ventilation mechanism is connected with an air port of the air bag, and the ventilation mechanism can convey air into the air bag or extract air in the air bag. The skin of the surgical site of a patient is cut, the stripping mechanism is inserted into the surgical site through the incision, the air bag is inflated through the ventilation mechanism, the soft tissue at the incision can be expanded by expanding the air bag, and therefore the skeleton is leaked out, and the stripping mechanism can strip the periosteum conveniently.

FIELD: otorhinolaryngology.SUBSTANCE: under endotracheal anesthesia, an endoscope equipped with optics and an instrument for removing pathological contents of the maxillary sinus are inserted into the nasal passage. The inferior nasal concha is displaced medially using a raspatory. Then, stepping back from the edge of the piriform opening by 1.5–2.0 cm in the caudal direction, a mucoperiosteal flap of the lateral wall is separated in the lower nasal passage. The mucoperiosteal flap is displaced posteriorly, exposing the bone skeleton in the projection of the inferomedial angle of the maxillary sinus. Next, using a cold plasma coblator, in ablation mode, the mucous surface of the bone skeleton is evaporated for 2–3 seconds, followed by coagulation of small vessels. Then, a bone valve measuring 10–15 mm is formed from the exposed bone skeleton. The bony valve is retracted in the caudal direction, forming an antrostomy. A 70-degree endoscope is inserted through the formed antrostomy and the pathological contents of the sinus are visualized. In this case, if the cyst is visualized with a coblator in ablation mode, the cyst is evaporated along with its contents, and the remaining cyst is captured and removed. If a polyp is visualized, the polyp stalk is first evaporated, and then the remaining part of the polyp is removed. If a foreign body is visualized, it is removed with forceps. In this case, if the foreign body is encapsulated or located in the thickness of the mucosa, a coblator in ablation mode evaporates part of the mucosa until the foreign body is exposed, and then removed. Next, the sinus cavity is washed with saline solution. The antrostomy is closed with a bone flap. The formed mucoperiosteal flap is placed back in its original place.EFFECT: method allows for endoscopic endonasal removal of pathological contents from the maxillary sinuses with a minimal risk of cyst / polyp recurrence and postoperative complications, reduced blood loss during surgery, shortened surgical time, postoperative rehabilitation periods, and temporary disability.3 cl, 3 ex

A semi-closed negative pressure restoration for jaw defects comprises a base body and a closed shell, the base body is of a titanium alloy net structure formed through 3D printing, the two ends of the base body can be matched with bone fracture ends in an attached mode, and a negative pressure suction base tube is embedded into the surface of the closed shell inwards. And an outer tube opening of the negative pressure suction base tube is used for being connected with a suction tube of a negative pressure suction device in a sealing manner. Aiming at the situation that the jaw defect degree is that periosteum does not exist, the titanium alloy prosthesis is manufactured through 3D printing, the two ends of the prosthesis are tightly attached to the bone fracture end, the outer surface of the prosthesis is in a closed state, and therefore it is guaranteed that the interior of the prosthesis is in a negative pressure environment and the interior of the prosthesis is of a bone trabecula imitating grid structure under the situation that the periosteum does not exist; a negative pressure suction base tube is arranged at the lower end of the negative pressure suction tube and communicated with a suction tube of a negative pressure suction device, intermittent negative pressure suction (15-30 min / h) is carried out, growth and differentiation of local osteoblasts are promoted, and rapid osteogenic repair in a repair body is promoted.

The utility model relates to the technical field of medical instruments, in particular to a periosteum detacher for orbital surgery, which comprises a handle, a first detaching knife and a second detaching knife. The first stripping knife comprises a first connecting rod and a first stripping head which are connected with each other; a plurality of reinforcing ribs are arranged on the first connecting rod in the circumferential direction, the side faces of the reinforcing ribs are fixedly connected with the first connecting rod, and the bottoms of the reinforcing ribs are fixedly connected with the handle; the second stripping knife comprises a second connecting rod and a second stripping head which are connected with each other, a snakelike structure is arranged in the middle of the second connecting rod, and the snakelike structure comprises a plurality of linear sections and arc-shaped sections which are connected in sequence. According to the periosteum detacher for the orbital surgery, medical staff can feel finer feedback in the operation process, the use force and depth can be conveniently controlled, and the surgery safety is improved.

The utility model provides a device convenient for back insertion of a periosteum implanting nail, which belongs to the technical field of oral implanting auxiliary tools, and comprises a tube body, and a driving piece, a push rod, a spring and a nail claw which are positioned in the tube body, one end of the push rod in the length direction is fixedly connected with the driving piece, the other end of the push rod is fixedly connected with the nail claw, and the push rod is sleeved with the spring; the side face of the pipe body is provided with a sliding window in the length direction of the pipe body, and the driving piece is connected with a sliding key which is located outside the pipe body and can slide along the sliding window. A through hole is formed in one end of the tube body, and the nail claw can extend out of the tube body from the through hole under the action of the push rod to grab a periosteum implant nail. By means of the device facilitating back insertion of the periosteum implanting nail, the periosteum implanting nail can be stably and rapidly inserted into the nail containing box, and operation complexity is reduced.

The utility model belongs to the technical field of tooth periosteum separation, and particularly relates to a multifunctional dental implant periosteum separator which comprises a handle, one end of the handle is provided with a first operation portion, the first operation portion comprises an arc-shaped sheet plate and a sharp blade, the arc-shaped sheet plate is fixedly connected to one end of the handle, and the sharp blade is fixedly connected to the other end of the handle. The sharp cutting edge is arranged on the side wall of the front end of the arc-shaped sheet-shaped plate, a second working part is arranged at the other end of the handle, and the second working part comprises a bent sheet-shaped plate and two baffles; the doctor uses a third operation part on the periosteum separator to remove redundant bones; the first working part is a cutting edge, the second working part is a cutting edge, the third working part is a filing edge, the filing edge has a good cutting function, compared with the cutting edge, the filing edge is short and can bear larger pressure, and therefore the problems that the filing edge is passivated and broken can be effectively solved, the first working part has a periosteum separation function, the second working part has a bone scraping function, and the third working part has a bone removing function.

The utility model belongs to the field of medical instruments suitable for orthopedic surgery, and particularly relates to a periosteum distraction device for a skull, which comprises a strip-shaped distraction plate bent in an arc shape, a sleeve and a distraction nail provided with external threads, one end of the distraction plate is provided with a combination hole penetrating through the upper surface and the lower surface, and the combination hole is composed of a groove and a threaded hole; a boss matched with the groove in an inserted mode is arranged on the end face of one end of the sleeve, and the sleeve is inserted into the groove in the convex face direction of the stretching plate. The distraction nail penetrates through the sleeve and then is in threaded connection with the distraction plate, the nail tail of the distraction nail extends to the outside of the sleeve, and the nail head of the distraction nail extends to the concave face side of the distraction plate and is configured to make contact with the bone surface. According to the distraction device, the distraction plate can be driven to rotate integrally by rotating the sleeve through the inserting and matching structure of the groove and the sleeve, flexible adjustment of the position of the distraction plate is achieved, periosteum can be stimulated in a targeted mode, and therefore regeneration of subperiosteal blood vessels can be promoted.

The periosteum detacher comprises a handle, a first detacher body and a screwdriver, the first detacher body is fixedly connected to one end of the handle, the screwdriver comprises a first rod body, one end of the first rod body is provided with a screw head, and the other end of the first rod body is detachably connected to the other end of the handle. The screwdriver is detachably connected with the handle, so that the screwdriver can be detached in an operation without using the screwdriver to install a bone nail, the additional weight and occupied space are reduced, and the operation burden of an operation operator is reduced; the screwdriver can be installed in an operation where the screwdriver needs to be used for installing a bone nail, so that functionality is increased, and operation operators can use the bone nail conveniently. Meanwhile, the device has the advantages of being simple in structure, easy to implement, suitable for being installed and used in an existing orthopedic surgery, low in using cost and high in using benefit.

The utility model relates to the technical field of orthopedic surgical instruments, in particular to a pair of minimally invasive osteotomy guide forceps, which comprises a first forceps handle and a second forceps handle, the guiding clamp is reasonable and compact in structure, in the osteotomy process, only periosteum at the position to be subjected to osteotomy needs to be stripped, after the guiding clamp is closed, the left portion of the upper bendable clamp head and the left portion of the lower bendable clamp head can surround the periphery of a bone, the upper guiding groove and the lower guiding groove are synchronously combined, and at the moment, a fretsaw penetrates through the upper guiding groove and the lower guiding groove to conduct osteotomy. The fretsaws can be separated from the corresponding guide grooves to cut off the skeleton by alternately drawing the two ends of the fretsaws; during an operation, the fretsaw is protected by the upper bendable clamp head and the lower bendable clamp head, so that an operative incision cannot be expanded, peripheral nerves, blood vessels and soft tissues of bones can be effectively protected, unnecessary damage to surrounding tissues is avoided, the operation time is greatly shortened, the possibility of postoperative complications is reduced, and the postoperative rehabilitation time of a patient is shortened.

The utility model discloses an auditory ossicle prosthesis capable of rotating in two dimensions and adjusting and locking the length. The auditory ossicle prosthesis comprises a first fixing element connected to a periosteum and a second fixing element connected to a stapes plate, the first fixing element is installed at the head end of the first rod part, the tail end of the first rod part is installed at the head end of the second rod part in a pitching rotating mode, and the first rod part can be locked on the second rod part after angle adjustment is completed. The tail end of the second rod part can be horizontally and rotatably mounted in the second fixing element, the second rod part after angle adjustment can be locked on the second fixing element, and the length of the second rod part can be adjusted in the axial direction of the second fixing element under the action of external force. Two-dimensional rotation adjustment of the ossicle prosthesis, locking after two-dimensional rotation adjustment and length adjustment can be achieved.

The invention provides a cell microsphere induced bionic periosteum and a preparation method thereof, and belongs to the technical field of bionic periostems.The preparation method comprises the steps that firstly, a PDA-PCL support is prepared, then cell microspheres obtained through a 3D culture plate are loaded on the support, PDSCs in the cell microspheres are dispersed out of an initial cell aggregate through cell culture, and the PDSCs in the cell microspheres are dispersed out of the initial cell aggregate; rapidly proliferating to form a layer of compact cell functional membrane, and preparing to obtain the cell microsphere induced bionic periosteum; the bionic periosteum can provide high-density stem cells, and can continuously secrete bioactive factors necessary for osteogenic differentiation and angiogenesis, so that the bionic periosteum has excellent osteogenic and angiogenesis promoting functions. According to the method provided by the invention, the bionic periosteum for simulating a natural bone environment is created, and a new bone defect repair strategy is provided: the bionic periosteum generated by expanding the PDSCs in the PDA-PCL stent provides a promising way for promoting bone regeneration treatment.

The utility model discloses an intramedullary needle for treating fracture and convenient to hold, which is provided with a treatment section and a holding section for operating and holding, and a positioning structure for holding and positioning is further arranged on the holding section. The intramedullary needle conforms to tubular bone biological fixation, the treatment section can be effectively prevented from rotating in the surgical treatment operation process through the holding section, the penetration depth and path of the treatment section can be further accurately controlled, the treatment accuracy is improved, and the treatment duration is shortened. When the intramedullary needle is used in the treatment process of metacarpal bone fracture, further damage to fracture local hematoma and periosteum can be avoided through closed reduction, blood supply of sclerotin is protected, and fracture healing is facilitated. The intramedullary needle is small in trauma, small in wound scar and beneficial to attractiveness; intramedullary fixation retains the minimally invasive characteristic of kirschner wire fixation, and the fixing effect is more stable and lasting than that of a kirschner wire, and the articular surface is not damaged.

A memory alloy periosteal traction plate is provided, including a plate body and screws. A work surface, a proximal installation end, and a distal installation end are formed on the plate body. The work surface fits a surface of a curved long bone, and extends in a length direction of the long bone. The proximal installation end is located at one end, close to a proximal end of the long bone, of the plate body, and the distal installation end is located at one end, close to a distal end of the long bone, of the plate body. Both the proximal installation end and the distal installation end are firmly connected to the long bone through screws by means of multiple fixing points, the plate body can gradually transition from a bending state to a straight state by means of deformation.

The invention discloses a facial contour lifting method, and belongs to the technical field of medical cosmetology. According to the method, nine key injection points are determined and the quantity ratio is accurately controlled on the basis of Jiayden MD-Codes and Escherre C type injection techniques, and movable rivet points are added according to the face sagging condition. And 9, the contour of the rivet is lifted. High-quality hyaluronic acid is selected and injected into the periosteum or ligament of the face through a specific technique, and the rivet type lifting effect is achieved. A Heart-Inside love face aesthetic system is used as guidance, inner and outer contours are built, and facial highlight and shadow areas are remodeled by referring to makeup skills. Comprehensive face evaluation is carried out before an operation, a specific injection method is adopted during the operation, and careful nursing and effect evaluation adjustment are carried out after the operation. The method achieves personalized facial contour improvement, has the advantages of being minimally invasive, remarkable in effect, durable, stable and the like, can effectively improve the facial aging problem, and meets the beauty requirements of different crowds.

The application discloses a kind of biomimetic composite scaffold with periosteum-cortical bone-cancellous bone structure and its preparation method and application.The scaffold is assembled by independent periosteum biomimetic scaffold module and independent bone trunk biomimetic module.The periosteum biomimetic scaffold module is cylindrical tube structure hydrogel, loaded with zinc silicate particles and periosteum related cells, with the biological functions of promoting cartilage differentiation, secreting nerve and vascular factors and synthesizing periosteum matrix proteins.The bone trunk biomimetic scaffold module is cylindrical bioceramic, with multiple vertical pipes embedded in the dense layer of outer wall to simulate cortical bone, and with staggered structure inside to simulate cancellous bone.Animal experiments show that the biomimetic composite scaffold can effectively promote the integrated regeneration of bone trunk and periosteum in rabbit radial critical size defect model.Therefore, the application provides a new solution for the biomimetic design and regeneration repair of bone tissue engineering.

The utility model discloses a scalp scar incision knife for the edge of a bone window, which is divided into an L type and a T type, and each type is divided into two edging directions, namely a clockwise edging direction and an anticlockwise edging direction; the T-shaped scalpel comprises a scalpel handle, a first blade or a second blade, the scalp of a surgical part of a patient is transversely and longitudinally cut open at the same time through the additional arrangement of the first blade or the second blade, and the convenience of medical staff in surgical use is improved; a downward edged blade and an upward edged blade are arranged on the blade side, the skull side blade is edged downwards, periosteum and skull of a patient are separated, the downward blade can prevent the scalp from being too thin, and it is guaranteed that the blade is tightly attached to the surface of the skull to be pushed. The blade in the bone window is edged upwards, so that damage to meninx and brain tissue of a patient caused by the blade can be avoided, the use safety is improved, the situation that medical staff frequently replace tools in the operation process is avoided, and the use difficulty of the medical staff is reduced.

The invention discloses a bionic full-thickness gingival flap for implanting and repairing soft and hard tissue defects and a preparation method of the bionic full-thickness gingival flap, and relates to the technical field of biological materials. The functions of the natural gingival valve are simulated through layered design, the antibacterial peptide-collagen hydrogel serves as the bionic gingival valve epithelium to block bacteria, the porous collagen hydrogel serves as the bionic gingival valve intrinsic layer to provide mechanical support, and the compact collagen hydrogel serves as the bionic gingival valve periosteum layer to maintain the osteogenesis space. The material utilizes a honeycomb structure to promote epithelial regeneration, a loose network guides fibroblast migration, a zinc-rich microenvironment enhances osteogenic differentiation, and synergistic repair of soft and hard tissues is realized. By adopting the semi-permeable activation fibroblast paracrine effect of the collagen hydrogel, the limitation of traditional layer-by-layer repair is broken through, the problems of bone grafting area infection, bone meal displacement, space maintenance and the like are effectively solved, secondary trauma of autotransplantation is avoided, and an innovative solution is provided for alveolar bone regeneration.

1. Name of the product in this design: Gingival retractor. 2. Purpose of this design: To retract the gingival tissue or periosteum during oral cavity repair. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention discloses a bone-periosteum bionic stent for vascularized bone regeneration and a preparation method of the bone-periosteum bionic stent, and belongs to the technical field of bone repair. The stent comprises a bone bionic stent and a bionic periosteum, the bone bionic scaffold is of a hierarchical pore structure and is formed by compounding polycaprolactone, silk fibroin and beta-tricalcium phosphate through fused deposition 3D printing, and the surface of the bone bionic scaffold is subjected to alkali treatment so as to improve hydrophilicity and osteogenic activity; the bionic periosteum is printed on the surface of the bone bionic scaffold through a near-field direct writing technology and is composed of polycaprolactone, mineralized collagen and magnesium ions, and the mineralized collagen is distributed in the bionic periosteum in a gradient mode. Through integrated bionic design, structures and functions of natural bones and periosteum are simulated; the bone bionic support plays a role in mechanical support and bone formation promotion; the bionic periosteum rapidly releases magnesium ions in the early stage of degradation, and early vascularization is promoted; along with degradation, continuously released collagen induces mineralization of a collagen matrix in the later period; the stent has good cell compatibility and capability of promoting osteogenic differentiation and blood vessel formation.