64 results about "Muscle tissue" patented technology

The present invention relates to the use of GRP78 and peptides similar thereto or nucleic acids encoding the same. The peptides or nucleic acids according to the present invention can increase the expression of biomarkers having reduced expression in senescent cells, and thus can be used to restore the function of muscle tissue that has decreased in function due to aging, etc.

A composition has hyaluronic acid and one or more materials as an admixture. The hyaluronic acid is derived from a fascia tissue layer of an alligator, the fascia layer located below a hide and above muscle tissue. The one or more materials as the admixture to the hyaluronic acid can be a carrier, diluent or excipient. The hyaluronic acid is extracted from the fascia tissue layer in the form of an oil having an oily viscosity with a molecular weight of 30,000 or greater. The oil extracted includes the hyaluronic acid and includes sodium or salts of hyaluronic acid. The oil extracted is anti-inflammatory to human tissue.

This invention relates to molecular marker 1769 and its application in the identification of sex-reversed pseudomale individuals in the Northeast Forest Frog (Rana davidii), and pertains to the field of molecular markers. To address the current difficulty in identifying sex-reversed pseudomale individuals in the Northeast Forest Frog, this invention extracts the genome from the muscle tissue of the left hind limb of the Northeast Forest Frog. Using the extracted genomic DNA as a template, PCR amplification is performed using primer pairs containing the sequences shown in SEQ ID NO:1 and SEQ ID NO:2. The PCR amplification products are detected by electrophoresis on a 3% agarose gel. Phenotypic male individuals exhibiting the 1769 bp band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are genetically male Northeast Forest Frogs, i.e., true males. Phenotypic male individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are pseudomale individuals who have undergone sex reversal from genetically female to phenotypically male. Phenotypic female individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are female individuals.

This invention provides a method and device for displaying muscle tissue morphology based on a digital twin of the levator scapulae muscle. The method includes acquiring static magnetic resonance imaging data of the target user's shoulder and neck region, multi-angle dynamic optical motion capture data, and surface electromyography (EMG) signals of the target muscle group to construct multimodal physiological data of the levator scapulae muscle. Based on the static magnetic resonance imaging data, a static anatomical base model of the levator scapulae muscle is constructed using image segmentation and 3D reconstruction techniques. According to the multi-angle dynamic optical motion capture data and EMG signals, the activation sequence and corresponding activation intensity of the target nerve driving the contraction of the levator scapulae muscle under different movements are calculated. Based on the activation sequence and corresponding activation intensity of the target nerve, the static anatomical base model of the levator scapulae muscle is embedded into a pre-trained digital twin model of the levator scapulae muscle to obtain a target digital twin of the levator scapulae muscle. The input motion command is input into the target digital twin of the levator scapulae muscle, and the muscle tissue morphology results are output and displayed.

This invention relates to the molecular marker M-513 and its application in the identification of sex-reversed pseudomale individuals in the Northeast Forest Frog (Rana davidii), and pertains to the field of molecular markers. To address the current difficulty in identifying sex-reversed pseudomale individuals in the Northeast Forest Frog, this invention extracts the genome from the muscle tissue of the left hind limb of the Northeast Forest Frog. Using the extracted genomic DNA as a template, PCR amplification is performed using primer pairs containing the sequences shown in SEQ ID NO:1 and SEQ ID NO:2. The PCR amplification products are detected by electrophoresis on a 3% agarose gel. Phenotypic male individuals exhibiting a 513bp band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are genetically male Northeast Forest Frogs, i.e., true males. Phenotypic male individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are pseudomale individuals exhibiting sex reversal from genetically female to phenotypically male. Phenotypic female individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are female individuals.

The present invention disclosure relates to a rapid and cost-effective method for the isolation of genomic material from muscle tissues of mangrove crab for the molecular detection of bacterial pathogens. The methods increase the total recovery of genomic DNA from muscle tissues by heating to 100oC in addition to mechanical disruption of tissues by homogenization. The extracted and isolated genomic DNA using the present invention can 10 be used for the molecular detection of bacterial pathogens from muscle tissues of mangrove crab.

This invention relates to the molecular marker M-866 and its application in the identification of sex-reversed pseudomale individuals in the Northeast Forest Frog (Rana davidii), and pertains to the field of molecular markers. To address the current difficulty in identifying sex-reversed pseudomale individuals in the Northeast Forest Frog, this invention extracts the genome from the muscle tissue of the left hind limb of the Northeast Forest Frog. Using the extracted genomic DNA as a template, PCR amplification is performed using primer pairs containing the sequences shown in SEQ ID NO:1 and SEQ ID NO:2. The PCR amplification products are detected by electrophoresis on a 3% agarose gel. Phenotypic male individuals exhibiting the 866bp band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are genetically male Northeast Forest Frogs, i.e., true males. Phenotypic male individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are pseudomale individuals exhibiting sex reversal from genetically female to phenotypically male. Phenotypic female individuals lacking the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 are female individuals.

This invention discloses a method for improving the quality stability of frozen oysters and a frozen oyster meat product, relating to the field of aquatic product processing technology. The method for improving the quality stability of frozen oysters provided by this invention employs ultrasonic treatment combined with citric acid solution soaking. It utilizes the cavitation effect, microjets, and mechanical vibration generated when ultrasound propagates in a liquid medium to effectively disrupt the mass transfer resistance on the surface of oyster tissue, significantly promoting the penetration and uniform distribution of citric acid within the muscle tissue. This solves the problems of low penetration efficiency of active ingredients and insufficient internal tissue protection in traditional citric acid soaking treatments, achieving effective inhibition of lipid and protein oxidation. This invention features a simple process, high safety, requires no complex equipment, and is suitable for large-scale application in the aquatic product processing industry.

1. Name of the product in this design: Medical probe. 2. Purpose of this design: For physical therapy of muscle and connective tissue. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the key design points: 3D diagram of the combined state of Design 1. 5. The rear view of Component 1 of Design 1 is the same as the front view of Component 1 of Design 1, so the rear view of Component 1 of Design 1 is omitted; the right view of Component 1 of Design 1 is the same as the left view of Component 1 of Design 1, so the right view of Component 1 of Design 1 is omitted; the rear view of Component 2 of Design 1 is the same as the front view of Component 2 of Design 1, so the rear view of Component 2 of Design 1 is omitted; the right view of Component 2 of Design 1 is the same as the left view of Component 2 of Design 1, so the right view of Component 2 of Design 1 is omitted; the rear view of Component 1 of Design 2 is the same as the front view of Component 1 of Design 2, so the rear view of Component 1 of Design 2 is omitted; the right view of Component 1 of Design 2 is the same as the left view of Component 1 of Design 2, so the right view of Component 1 of Design 2 is omitted; Component 2 of Design 2 is the same as Component 2 of Design 1, so the rear view of Component 2 of Design 2 is omitted; the rear view of Component 1 of Design 3 is the same as the front view of Component 1 of Design 3, so the rear view of Component 1 of Design 3 is omitted; the right view of Component 1 of Design 3 is the same as the left view of Component 1 of Design 3, so the right view of Component 1 of Design 3 is omitted. 6. Other situations requiring explanation: The combination relationship between Component 1 of Design 1 and Component 2 of Design 1 is unique; the combination relationship between Component 1 of Design 2 and Component 2 of Design 1 is unique; the combination relationship between Component 1 of Design 3 and Component 2 of Design 3 is unique. 7. Design 3 is designated as the basic design.

The utility model discloses a kind of pulsating air hydraulic pressure cycle therapeutic instrument control circuit, it is related to control circuit technical field, including microcontrol unit, part selection button, mode selection button, on / off button, NFC card swiping instruction module, electrode intensity adjusting knob, host output port, pulse output control circuit, boost circuit, stimulation circuit, electrode, display module and power module;Pulse current and intermittent pressure and warm mode are generated using specific circuit, can directly stimulate nerve muscle tissue, effectively cause muscle excitement and contraction, simulate real person hammer back, knock, massage, massage and the actual feeling of fire pot improves part function.The control circuit structure of hand rehabilitation therapeutic instrument described in the utility model is simple, reasonable in design, and the circuit function is high in integration, and the circuit board is small in size, which provides a basis for the portability of hand rehabilitation instrument.

The application discloses a kind of myoglobin preparation process for chemiluminescence immunoassay quality control product, it is related to myoglobin preparation technical field, comprising the following steps: raw material pretreatment: after removing impurities of fresh pig heart muscle tissue, it is placed in automatic cleaning cutting equipment and is cut and cleaned, myoglobin extraction: muscle tissue after pretreatment is placed in grinding mechanism, and extraction fluid is added to grind, centrifugal separation: after extraction, mixed liquid is placed in high-speed centrifugal separation equipment and is centrifuged, to obtain supernatant, purification treatment: supernatant is purified by multistage filtration separation equipment, stabilization treatment: after purification, myoglobin solution is added with stabilizer, placed in gradient temperature control stirring system and stirred and mixed, low-temperature preservation, solve the problem that muscle tissue is cut into meat foam by manual shearing mode, grinding is not enough, so that separation effect is poor, leading to the problem that myoglobin purity is not high and activity is easily affected.

Methods and apparatus disclosed treat pain and mobility impairments by applying controlled subatmospheric pressure to skin over muscle tissue or joints during volitional muscle contractions against adaptive therapist resistance. Domes with basal openings sealing against skin perimeters, are evacuated to 13-90% of atmospheric pressure. Some embodiments have 3-10 second contraction intervals repeated at least three times per subatmospheric treatment cycle, before pressure is ramped to ambient pressure over at least 2 seconds. Results are improved range of motion, muscle strength, and pain reduction. Apparatus embodiments include vacuum manifolds, sensors for pressure and tissue distension, and optional integrated electrodes for performing TENS / STIM.

This invention relates to the field of pelvic floor muscle rehabilitation technology and discloses a pelvic floor muscle rehabilitation training device, including a contact shell, an air tube fixedly connected to the outer wall of the contact shell, and an electrode probe fixedly connected to the top of the contact shell. The surface of the airbag is disinfected, and the airbag is fitted onto the outer wall of the electrode probe. The other end of the air tube is inserted into the airbag and connected to it. The electrode probe is slowly inserted into the vagina, and the device is turned on. At the same time as the electrode probe is activated, the inflation device is activated to generate gas, which enters the airbag through the air tube. As the gas continues to enter, the airbag slowly expands. When the airbag expands to a certain volume, inflation stops, and it begins to contract within a certain period of time. This allows the airbag to expand moderately after inflation, conforming to the irregular shape of the vaginal wall, ensuring stable and uniform contact between the built-in electrode and the pelvic floor muscle tissue.

The application discloses CircSESN1 a gene, an overexpression vector thereof, a specific primer pair, a detection kit and application thereof. CircSESN1 The application also discloses application of the gene, the overexpression vector, the specific primer pair or the fluorescent quantitative detection kit in regulation of chicken skeletal muscle growth and development. CircSESN1 The application further discloses a method for inhibiting proliferation and / or promoting differentiation of chicken myoblasts. The detection kit provided by the application can be used for detecting

The present application belongs to the technical field of aquatic biology, molecular breeding and gene expression regulation, and particularly relates to a method for increasing the content of carotenoids in fish muscle. The method is to regulate the expression of beta-carotene oxygenase 2 (Bco2) gene or its functional homologous gene, reduce the cracking efficiency of carotenoids in vivo, thereby promoting the accumulation of carotenoids in fish muscle tissue, and achieving the improvement of muscle color and the improvement of meat quality. The present application can significantly reduce the expression level of bco2l gene, promote the increase of carotenoid content in muscle, and improve the meat color quality and economic value of Cynoglossus semilaevis. The method is simple and efficient, and has good popularization and breeding application prospect.

The application provides a massage device, comprising: a shell, an outer surface of which is provided with a massage structure; a light therapy assembly arranged in the shell; an electrode assembly connected with the shell and at least partially extending out of the shell, the electrode assembly being used to contact the skin of a human body to form a micro-current loop; the shell is provided with a light-transmitting area at least at positions corresponding to the light therapy assemblies, and light emitted by the light therapy assemblies is emitted out through the light-transmitting area. The massage device provided by the application has the massage structure arranged on the outer wall of the shell, so that the massage device can perform rolling massage and relieve muscle tension and pain; the light emitted by the light therapy assemblies can improve the corresponding muscle tissue and relieve pain and discomfort; the part of the electrode assembly extending out of the shell can contact the skin of the human body and form a long micro-current loop, the micro-current formed by the electrode assembly can stimulate acupoints, promote blood circulation and energy balance, the massage device integrates multiple functions of light therapy, massage and acupoint stimulation, and has a small overall volume, so that the massage device is convenient to carry and use.

This invention provides a compound nutritional powder with post-exercise recovery function and its preparation method, relating to the field of food processing technology. The preparation method of the compound nutritional powder with post-exercise recovery function includes the following steps: weighing raw materials according to a certain proportion and mixing them evenly to obtain the compound nutritional powder with post-exercise recovery function; the raw materials, by weight, include: 20-50 parts glucose powder, 20-40 parts maltodextrin, 10-25 parts white thorn fruit powder, 2-10 parts soybean peptide powder, and 2-8 parts yak collagen peptide powder. This invention, by compounding glucose powder, maltodextrin, white thorn fruit powder, soybean peptide powder, and yak collagen peptide powder in a specific proportion, combined with vacuum freeze-drying, cell wall breaking, grading and sieving of white thorn fruit powder, and ultraviolet irradiation treatment of some raw materials, achieves the goals of rapid energy supply after exercise, promoting muscle tissue recovery, improving body composition, and enhancing product safety and stability, and has good prospects for the development and application of sports nutrition foods.

This invention discloses a mouse experimental method for detecting the tissue distribution of exogenous oxytocin, belonging to the field of biotechnology. Specifically, oxytocin is injected into or nasally sprayed into oxytocin knockout mice, and body tissues, including but not limited to brain tissue, mammary gland tissue, blood, heart tissue, uterine tissue, bone tissue, and muscle tissue, are collected at different time points. The tissue distribution and content of oxytocin are then detected using liquid chromatography-mass spectrometry (LC-MS / MS). This experimental method allows for a wider range of experimental samples, not just focusing on brain tissue and blood; it also has higher sensitivity and stronger specificity; and by utilizing oxytocin gene knockout mice, it eliminates the influence of endogenous oxytocin, providing certain assistance for subsequent animal experiments and clinical research on oxytocin.

This invention provides a method for site-specific replacement of the creatine kinase promoter in the Huaxi bovine gene promoter, belonging to the field of animal gene editing and genetic breeding technology. It also provides a method for enhancing the function of bovine muscle cells. FTO Gene expression reagents include crRNA for upstream site knockout, crRNA for downstream site knockout, a Cas12i nuclease expression vector, and an FTO homologous substitution vector; the FTO homologous substitution vector includes... FTO upstream homologous arm of gene promoter, MCK gene promoter and FTO Downstream homologous arm of the gene promoter. The reagent was used in West China bovine cells. FTO Application in gene promoter replacement. This invention can specifically improve the expression efficiency of genes related to fat development in muscle tissue, providing an efficient and precise technical means for the genetic improvement of the performance of beef from Western China.

The application relates to a molecular marker M-428 related to identification of sex-reversed pseudo-male individuals of Rana dybowskii and application thereof, and relates to the field of molecular markers. In order to solve the problem that sex-reversed pseudo-male individuals of Rana dybowskii are difficult to identify at present, the application extracts the genome of the left hind limb muscle tissue of Rana dybowskii, takes the extracted genomic DNA as a template, and carries out a PCR amplification reaction with a primer pair containing the sequences shown in SEQ ID NO:1 and SEQ ID NO:2. The PCR amplification product is subjected to electrophoresis detection through 3% agarose gel, the amplification result has a 428bp band corresponding to the nucleotide sequence shown in SEQ ID NO:3, the phenotype male individual is a genetic male Rana dybowskii, i.e. a true male individual. The phenotype male individual missing the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 is a pseudo-male individual with sex reversal from a genetic female to a phenotype male. The phenotype female individual missing the band corresponding to the nucleotide sequence shown in SEQ ID NO:3 is a female individual.

The application discloses a starch-based edible scaffold and a preparation method and application thereof, and belongs to the technical field of cell scaffold materials. The edible starch is used as a base material, and a semi-interpenetrating network (Semi-IPN) hydrogel scaffold is constructed through heat-induced self-assembly, and the scaffold has good biocompatibility and edible safety. The preparation method can accurately control the elastic modulus and mechanical properties of the scaffold, so that the scaffold is suitable for providing tensile stress stimulation for fish myoblasts. Thanks to the above-mentioned characteristics, the scaffold can not only effectively support the adhesion and proliferation of fish myoblasts, but also significantly promote the directional differentiation of the fish myoblasts, and form a biomimetic muscle tissue. The application provides an innovative and performance-controllable cell scaffold solution for producing fish culture meat products which do not need to be separated from the scaffold and can be directly eaten.

An improved locking structure of orthopedic steel plate, comprising a steel plate, an outer sleeve and an inner core, the steel plate is provided with a through hole for the screw body to pass through, one end of the outer sleeve is fixedly connected with the steel plate, and the inner hole of the outer sleeve is coaxial with the through hole provided on the steel plate, the inner hole of the outer sleeve forms a guide channel for guiding the screw to be screwed in, and the inner core is detachably arranged in the outer sleeve, and the guide hole in the inner core is used for guiding the drilling of the drill bit. In the operation, the guide hole of the inner core is used to guide the drill bit to accurately drill, so that the lower end of the inner core is matched with the conical internal thread of the through hole, which can effectively constrain the radial deviation of the drill bit and ensure the accuracy of the drilling position. After the drilling is completed, the inner core is taken out, and then the screw is screwed in through the guide channel of the outer sleeve, the guide channel can constrain the radial displacement of the screw, so that the screw accurately passes through the through hole and is screwed into the predetermined position of the bone, avoiding the deviation of the screw into the muscle tissue, greatly improving the safety and accuracy of the operation, and facilitating the installation and disassembly operation according to the needs in the operation.

The application discloses a kind of digital multi-modal muscle isometric training detection method and system.The detection method includes: collecting the skeletal key point data and muscle tissue hardness data when patient executes muscle isometric training;Judge whether the training posture of patient and effort is up to standard;Record the training data of patient in up to standard state;Training data is transmitted to cloud platform, based on pre-trained GAMLSS model, corresponding percentile standard curve of the attribute of patient is matched, to convert the muscle tissue hardness data of patient in up to standard state into percentile score;Based on the training performance of patient's percentile score evaluation, and provide training feedback.Using the present application can automatically monitor patient muscle isometric rehabilitation training and provide training feedback in home scene, save the time cost of patient.And, the present application can adopt different detection standards for different users, to adapt to the training situation of different users.

This invention discloses the application of tyrosol in enhancing oxygen supply and thus improving energy supply, such as combating fatigue and improving athletic and / or cognitive performance. Enhancing oxygen supply includes increasing arterial blood oxygen saturation and / or muscle tissue oxygen saturation. Combating fatigue includes enhancing physical endurance and metabolism, reducing physical and mental fatigue, prolonging muscle and nerve working time, and / or maintaining muscle and nerve efficiency. Improving athletic performance includes enhancing the body's aerobic metabolic capacity, reducing lactic acid buildup, reducing post-exercise muscle soreness, and improving recovery speed. Improving cognitive performance includes reducing depression and anxiety; enhancing learning ability, memory, concentration, focus, reaction time, and alertness, especially in hypoxic environments and / or during exercise. Tyrosol enhances oxygen supply, thereby combating fatigue and improving athletic and cognitive performance.

This invention discloses a chicken embryo fibroblast, its preparation method, and its application, relating to the field of biopharmaceutical technology. The preparation method of the chicken embryo fibroblast includes the following steps: S1, providing chicken embryos and obtaining the muscle tissue of the chicken embryos; S2, mixing the muscle tissue with a plant-derived compound digestion solution, and sequentially performing digestion, purification, and primary culture treatment using a serum-free special culture medium to obtain primary chicken embryo fibroblasts; wherein, the plant-derived compound digestion solution includes bromelain and papain. This invention, using a plant-derived compound digestion solution and a serum-free special culture medium, significantly improves the batch-to-batch stability, cell yield, and cell purity of the cells, reducing the risk of exogenous viral contamination. Therefore, the prepared chicken embryo fibroblasts exhibit high batch-to-batch stability and good reproducibility in viral culture.

This utility model relates to the field of medical devices, specifically a reverse separation forceps, comprising the following components: a positioning post one, which is fitted onto the forceps handle; a forceps handle, on which two symmetrical posts are provided; a forceps bar, which is mounted on the forceps handle, and a forceps arm is provided between the forceps handle and the forceps bar; a forceps arm, on which a second positioning post is provided; a forceps tip, which is located at the end of the forceps bar. The forceps arm connects the forceps handle and the forceps bar, acting as a lever to provide external force when muscle tissue needs to be separated; the forceps arm has positioning posts for controlling the accuracy of the left and right forceps bar alignment and limiting the pinching position, while also acting as a rocker arm to ensure precise contact and separation of the forceps tip, thus improving the accuracy of grasping muscle tissue during surgery and the separation force required to separate the muscle tissue.

The methods described herein provide a modified VP1 capsid capable of preferentially targeting a gene of interest (GOI) within muscle tissue and a recombinant adeno-associated virus (rAAV) having a GOI encapsidated with the modified VP1 capsid and uses thereof.

This invention relates to the field of biomechanics research technology and discloses an architectural device for studying rotator cuff biomechanics. The device includes a frame assembled from multiple alloy profiles. A support base is fixedly mounted on the bottom of the frame via a truss, and a scapular plate is obliquely mounted on one side of the support base. Multiple columns are bolted to the left side of the frame. Each column has two pulley assemblies connected to its sidewall. One pulley assembly is connected to a loading mechanism, and the other is connected to a support mechanism. The loading mechanism is movably mounted on the sidewall of the column and can generate linearly varying tension. This architectural device for studying rotator cuff biomechanics can apply linear tension to the rotator cuff muscle tissue in multiple directions, simulating the effect of muscle contraction on the humerus. It can also reverse the pulling action on the humerus to observe the contraction and extension state of the rotator cuff muscle tissue, which is beneficial for medical research and teaching demonstrations.