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1043 results about "Muscle tissue" patented technology
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Muscle tissue is a soft tissue that composes muscles in animal bodies, and gives rise to muscles' ability to contract. This is opposed to other components or tissues in muscle such as tendons or perimysium. It is formed during embryonic development through a process known as myogenesis.
Transducer for embedded bio-sensor using body energy as a power source
InactiveUS20050261563A1Improve accuracyAccurate measurementTelemedicineEndoradiosondesMuscle tissueVoltage pulse
Provided is a bio-sensor system which utilizes radio frequency identification technology and which includes a remote transponder in wireless communication with an implantable on-chip transponder. A power supply collects alternating current voltage pulses from an electro-active polymer generator embedded in muscle tissue for generating power for the on-chip transponder. The power supply is specifically adapted to provide a stable and precise sensor reference voltage to a sensor assembly to enhance the accuracy of measurements of a physiological parameter of a patient. The remote transponder receives data representative of the physiological parameter such as glucose concentration levels. The data is processed and transmitted to the remote transponder by the on-chip transponder. The precision and stability of the sensor reference voltage is enhanced by the specific circuit architecture of a glucose sensor to allow for relatively accurate measurement of glucose concentration levels without the use of a microprocessor.
Owner:JAMM TECH INC
Implantable medical electrical stimulation lead fixation method and apparatus
InactiveUS6999819B2Optimize locationQuick placementSpinal electrodesExternal electrodesMuscle tissueMedicine
Owner:MEDTRONIC INC +1
Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves
InactiveUS20060089688A1Reduce wrinklesSurgical needlesSurgical instrument detailsMuscle tissueWrinkle skin
An apparatus and method for reducing wrinkles in the skin tissue of a patient. The method includes detecting a nerve. The nerve can be detected by inserting an electrode into the skin tissue, delivering a current and then observing any stimulation of muscle tissue. The process of inserting the electrode, delivering current and detecting muscle stimulation may be repeated at a plurality of different skin location to trace the nerve. Once the nerve is traced, the electrode can be inserted into the skin at various locations, either at or adjacent to the nerve, and deliver energy into the tissue at a level sufficient to disrupt interaction between the nerve and the adjacent muscle. Once the nerve / muscle interaction is disrupted the muscle will be relaxed and the wrinkle(s) will either be removed or reduced.
Owner:REFRACTEC
Minimal access lumbar diskectomy instrumentation and method
InactiveUS6849064B2Prevent surfaceEasy to separateCannulasInfusion syringesMuscle tissueSkin surface
A minimal incision maximal access system allows for maximum desirable exposure along with maximum access to the operative field utilizing a minimum incision as small as the METRx and Endius systems. Instead of multiple insertions of dilating tubes the design is is a streamlined single entry device to avoid repetitive skin surface entry. The system offers the capability to expand to optimum exposure size for the surgery utilizing hinged bi-hemispherical or oval working tubes applied over an introducer obturator which is controllably dilated to slowly separate muscle tissue. Deeper end working and visualization areas with maximum proximal access and work dimensions are provided to makes the operative procedure safer in application and shorten the surgeons's learning curve because it most closely approximates the ability to use open microdiskectomy techniques.
Owner:K2M
Systems and methods for automated muscle stimulation
ActiveUS20100004715A1Prevent and retard muscle atrophyLimited useElectrotherapyElectromyographyElectricityMuscle tissue
The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes and sensors may be provided, such that signals provided by the sensors may affect the signals provided to the stimulation electrodes, thus providing a feedback. Stimulation electrodes may be provided on a stimulation pad and sensors may be provided on a sensing pad, which may be designed to conform to an anatomical feature. A system for neuromuscular electrical stimulation may also include temperature sensitive elements that may help prevent burns, especially for comatose, sedated, or patients in critical condition. The system may also include a cooling assembly for a stimulation pad.
Owner:SAGE PRODS
Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration
A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.
Owner:MACROPORE
Testing Efficacy of Therapeutic Mechanical or Electrical Nerve or Muscle Stimulation
InactiveUS20070265675A1Rule out the possibilityReduce complicationsElectrotherapyMuscle tissuePelvic nerve
Methods and apparatus for testing of the efficacy of therapeutic stimulation of pelvic nerves or musculature to alleviate one of incontinence or sexual dysfunction are disclosed. A therapy delivery device is operable in a therapy delivery mode and a test mode and an evoked response detector is employed in the test mode to detect the evoked response to applied test stimuli. The test stimuli parameters of the test stimulation regimen are adjusted prior to delivery of each test stimulation regimen, and the evoked responses to the applied test stimulation regimens are compared to ascertain an optimal test stimulation regimen. The therapy stimulation regimen parameters are selected as a function of the test electrical stimulation parameters causing the optimal evoked response.
Owner:AMS RES CORP
Apparatus and method for elongation of a papillary muscle
InactiveUS20060167474A1Avoiding significant morbityAvoiding mortalityDiagnosticsHeart valvesMuscle tissuePapillary muscle
A system and method for treating a dilated heart valve by elongating a papillary muscle. The system comprises a delivery catheter 110 and a holding catheter 130. The system further comprises a muscle elongation device 200 including at least two clamping rings 210, 215 slidably connected by at least one connecting rod 220. The muscle elongation device 200 is delivered to a papillary muscle 560 associated with the dilated heart valve, where it is released from the delivery catheter 110 and the clamping rings 210, 215 wrap about and engage the papillary muscle. The muscle tissue is cut between the clamping rings 210, 215, which then move away from each other to a predetermined position, thus permitting the papillary muscle to elongate.
Owner:MEDTRONIC VASCULAR INC
System and method for imaging and treatment of tumorous tissue in breasts using computed tomography and radiotherapy
InactiveUS20060262898A1Preventing formation of vacuumInhibition formationMaterial analysis using wave/particle radiationRadiation/particle handlingMuscle tissueTumour tissue
The present invention provides a system 10 for irradiating a breast 20 of a patient 22. The system 10 comprises a gantry 12 rotatable about a horizontal axis 14 and comprising a radiation source 16 for generating a radiation beam 18 and a detector 24 spaced from the radiation source 16, and a barrier 26 disposed between the patient 22 and the gantry 12. The barrier 26 is provided with an opening 30 adapted to allow a breast 20 passing therethrough to be exposed to the radiation beam 18. In some embodiments, the barrier 26 is provided with an opening 30 adapted to allow both the breast 20 and the tissue leading from the breast to axilla and the muscle tissue of the adjacent chest wall passing therethrough to be exposed to the radiation beam 18.
Owner:VARIAN MEDICAL SYSTEMS
Implant anchor systems
InactiveUS6986784B1Improve anchoring abilityIncreased durabilityStentsEar treatmentMuscle tissueImplanted device
The present invention provides anchoring mechanisms for tissue implants. The anchors are integrated as part of the structure of the implant and serve to resist migration of the implant from highly dynamic muscle tissue such as the myocardium of the heart. In implant devices configured as a flexible coil, various attributes of the coil may be altered to increase the anchoring capability of the device. The flexibility of the device may be increased to resist migration by changing the coil filament thickness, pitch or filament material. Alternatively, the end coil may be altered to have a broader cross-sectional profile in engagement with the tissue or may include an anchoring barb. Additionally, methods of implanting a tissue implant device are provided.
Owner:CR BARD INC
Modified and stabilized GDF propeptides and uses thereof
InactiveUS7202210B2Prevent practical therapeuticPrevent prophylactic utilityFungiBacteriaAcute hyperglycaemiaMuscle tissue
Modified and stabilized propeptides of Growth Differentiation Factor proteins, such as GDF-8 and Bone Morphogenetic Protein-11, are disclosed. Also disclosed are methods for making and using the modified propeptides to prevent or treat human or animal disorders in which an increase in muscle tissue would be therapeutically beneficial. Such disorders include muscle or neuromuscular disorders (such as amyotrophic lateral sclerosis, muscular dystrophy, muscle atrophy, congestive obstructive pulmonary disease, muscle wasting syndrome, sarcopenia, or cachexia), metabolic diseases or disorders (such as such as type 2 diabetes, noninsulin-dependent diabetes mellitus, hyperglycemia, or obesity), adipose tissue disorders (such as obesity), and bone degenerative diseases (such as osteoporosis).
Owner:WYETH LLC
Membrane with tissue-guiding surface corrugations
A resorbing, flexible implant in the form of a continuous macro-porous sheet (42) is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vitro repair. The membrane (42) has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature, and connective tissue cells derived from the adjacent soft tissues including the periosteum, can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature, and does not collapse.
Owner:MACROPORE
Transgenic non-human animals expressing a truncated activin type II receptor
The present invention provides a substantially purified growth differentiation factor (GDF) receptor, including a GDF-8 (myostatin) receptor, as well as functional peptide portions thereof. In addition, the invention provides a virtual representation of a GDF receptor or a functional peptide portion thereof. The present invention also provides a method of modulating an effect of myostatin on a cell by contacting the cell with an agent that affects myostatin signal transduction in the cell. In addition, the invention provides a method of ameliorating the severity of a pathologic condition, which is characterized, at least in part, by an abnormal amount, development or metabolic activity of muscle or adipose tissue in a subject, by modulating myostatin signal transduction in a muscle cell or an adipose tissue cell in the subject. The invention also provides a method of modulating the growth of muscle tissue or adipose tissue in a eukaryotic organism by administering an agent that affects myostatin signal transduction to the organism.
Owner:THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
GASP1: a follistatin domain containing protein
Owner:WYETH LLC
Augmentation of muscle contractility by biphasic stimulation
InactiveUS6343232B1Improved electrical stimulationExtend battery lifeHeart stimulatorsArtificial respirationSmooth muscleMuscle tissue
Augmentation of electrical conduction and contractility by biphasic stimulation of muscle tissue. A first stimulation phase has a first phase polarity, amplitude, and duration. The first stimulation phase, which acts as a conditioning mechanism, is administered at no more than a maximum subthreshold amplitude. A second stimulation phase has a second polarity, amplitude, and duration. The two phases are applied sequentially. Contrary to current thought, anodal stimulation is applied as the first stimulation phase, followed by cathodal stimulation as the second stimulation phase. In this fashion, pulse conduction through muscle is improved, together with an increase in contractibility. Furthermore, this mode of biphasic stimulation reduces the electrical energy required to elicit contraction. In addition, the conditioning first stimulation phase decreases the stimulation threshold by reducing the amount of electrical current required for the second stimulation phase to elicit contraction. The muscle tissue encompassed by the present invention includes skeletal (striated) muscle, cardiac muscle, and smooth muscle.
Owner:MR3 MEDICAL LLC
Resorbable, macro-porous non-collapsing and flexible membrane barrier for skeletal repair and regeneration
A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.
Owner:MACROPORE BIOSURGERY INC
Ultrasound-based treatment methods for therapeutic treatment of skin and subcutaneous tissues
The disclosure provides a method and apparatus for noninvasive and minimally-invasive treatment of skin and subcutaneous tissues with ultrasound with or without nano- or microparticles. The treatment includes, but is not limited to, hair removal, skin rejuvenation (wrinkle removal), scar removal, treatment of spider veins and varicose veins, removal of birthmarks, acne treatment, wound treatment, abnormal pigmentation and stretch mark removal, abnormal tissues in skin and subcutaneous layers, and tattoo removal. Skin and subcutaneous tissues which can be treated with the methods described include, but are not limited to, the dermis, epidermis, subcutaneous fat, connective tissue, muscle tissue, blood vessels, scar tissues, tendons, and cartilage tissues, and abnormal tissues in skin and subcutaneous layers. The disclosure is especially applicable to hair removal and skin rejuvenation.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Systems and Methods of Powered Muscle Stimulation Using an Energy Guidance Field
ActiveUS20100217349A1Avoid coolingEliminate currentElectrotherapyTherapeutic coolingMuscle tissueSkin surface
Owner:SAGE PRODS
Acute and chronic electrical signal therapy for obesity
InactiveUS6993391B2Reduce the cross-sectional areaLower the volumeInternal electrodesExternal electrodesMuscle tissueObesity
Apparatus is provided for treating a condition such as obesity. The apparatus includes a set of one or more electrodes, which are adapted to be applied to one or more respective sites in a vicinity of a body of a stomach of a patient. A control unit is adapted to drive the electrode set to apply to the body of the stomach a signal, configured such that application thereof increases a level of contraction of muscle tissue of the body of the stomach, and decreases a cross-sectional area of a portion of the body of the stomach for a substantially continuous period greater than about 3 seconds.
Owner:TYLERTON INT INC
Methods for treating muscle diseases and disorders
InactiveUS7037888B1Reduce the amount of solutionQuality improvementNervous disorderPeptide/protein ingredientsSmooth muscleDisease
The invention relates to methods of treating diseases and disorders of the muscle tissues in a vertebrate by the administration of compounds which bind the p185erbB2 receptor. These compounds are found to cause increased differentiation and survival of cardiac, skeletal and smooth muscle.
Owner:ACORDA THERAPEUTICS INC
Implantable vascular access device with ceramic needle guard insert
InactiveUS7713251B2Increase the areaReduce coagulationMedical devicesMuscle tissueVascular Access Devices
The present invention provides an improved vascular access port comprising a port base with a metallic dish insert molded (or bonded) into the bottom of the reservoir. In one embodiment, a single reservoir is provided. In another embodiment, plural reservoirs are provided. The metallic bottom of the reservoir provides a hard surface that will resist abrasion and puncture by the access needles used to infuse medication or withdraw blood. Additionally, the single and dual ports can include exit ports that are intended to better anatomically fit into the subcutaneous areas around muscle tissue.
Owner:PRIMO MEDICAL GRP INC
Method and device for soft tissue treatment
InactiveUS20060211958A1Good effectReduce unwanted damageUltrasound therapyChiropractic devicesMuscle tissueConnective tissue fiber
A method and system for non-invasive treatment of a soft tissue, such as adipose tissue, muscle tissue or connective tissue. The apparatus comprises an applicator configured to apply a pressure pulse to the skin surface having a negative pressure phase with respect to ambient pressure. The method comprises applying at least one pressure pulse to the skin surface overlying the soft tissue, where the pressure pulse has at least one negative pressure phase.
Owner:SYNERON MEDICAL LTD
Tissue infiltratable prosthetic device incorporating an antimicrobial substance
The invention relates to prosthetic devices that include antimicrobial substances for reducing microbial infection, and method of using such implants for repairing, reconstructing and / or augmenting a defect or a weakness in a wall of a muscle, tissue or organ.
Owner:CR BARD INC
Devices and Systems for Stimulation of Tissues
ActiveUS20140005759A1Low thermal conductivityLower skin temperatureElectrotherapyDiagnostic recording/measuringMuscle tissueSkin surface
Owner:SAGE PRODS
Systems and methods for fixation of adjacent vertebrae
InactiveUS20050038434A1Permit fusionReduce infectionSuture equipmentsInternal osteosythesisMuscle tissueDilator
A method for internal fixation of vertebra of the spine to facilitate graft fusion includes steps for excising the nucleus of an affected disc, preparing a bone graft, instrumenting the vertebrae for fixation, and introducing the bone graft into the resected nuclear space. Disc resection is conducted through two portals through the annulus, with one portal supporting resection instruments and the other supporting a viewing device. The fixation hardware is inserted through small incisions aligned with each pedicle to be instrumented. The hardware includes bone screws, fixation plates, engagement nuts, and linking members. In an important aspect of the method, the fixation plates, engagement nuts and linking members are supported suprafascially but subcutaneously so that the fascia and muscle tissue are not damaged. The bone screw is configured to support the fixation hardware above the fascia. In a further aspect of the invention, a three component dilator system is provided for use during the bone screw implantation steps of the method.
Owner:MATHEWS HALLETT H
Modified and stabilized gdf propeptides and uses thereof
InactiveUS20070149455A1Avoid utilizationImproved pharmacokinetic propertiesFungiBacteriaMuscle tissueAmytrophic lateral sclerosis
Modified and stabilized propeptides of Growth Differentiation Factor proteins, such as GDF-8 and Bone Morphogenetic Protein-11, are disclosed. Also disclosed are methods for making and using the modified propeptides to prevent or treat human or animal disorders in which an increase in muscle tissue would be therapeutically beneficial. Such disorders include muscle or neuromuscular disorders (such as amyotrophic lateral sclerosis, muscular dystrophy, muscle atrophy, congestive obstructive pulmonary disease, muscle wasting syndrome, sarcopenia, or cachexia), metabolic diseases or disorders (such as such as type 2 diabetes, noninsulin-dependent diabetes mellitus, hyperglycemia, or obesity), adipose tissue disorders (such as obesity), and bone degenerative diseases (such as osteoporosis).
Owner:WYETH LLC
Method and apparatus for creation of drug delivery and/or stimulation pockets in myocardium
An apparatus and method for creating drug-filled pockets within muscle tissue, such as myocardium of the heart for increasing angiogenesis. More particularly, the apparatus has an excising assembly with a dilator tip for penetrating and advancing through the surface and body of a muscle or organ, such as the heart. Preferably, the dilator tip has a low level laser optical fiber emission to ease the passage of the excising assembly and provide thermal damage which also stimulates angiogenesis. More preferably, the dilator tip also disperses a pharmacologically active substance as the apparatus is passed through the tissue and / or creates pockets. The excising assembly is connected to a hand-held control device from which the operator pushes a switch to activate a punching mechanism within the excising assembly. The punching mechanism cuts a discrete piece of muscle tissue and traps it within the excising assembly leaving a pocket in the remaining muscle tissue. The excising assembly may also optionally release a bolus of the pharmacologically active substance into the pocket so created. Most preferably, there is a timing mechanism to measure the contraction of the heart, and the timing mechanism is synchronized with the operator's switch on the hand-held device to ensure that the punching occurs at maximum contraction of systole. A measurement guide determines how much excised tissue is trapped in the reservoir of the excising assembly. At a threshold level of filling, the surgeon will remove the excising assembly from the hand-held control device and open the punching mechanism for release of tissue. More preferably, the threshold level of filling will automatically turn off the switch to the punching mechanism to indicate to the surgeon the need to empty the excising assembly of tissue.
Owner:ECLIPSE SURGICAL TECH
Acute and chronic electrical signal therapy for obesity
InactiveUS20060074459A1Reduce the cross-sectional areaLower the volumeInternal electrodesExternal electrodesMuscle tissueObesity
Owner:TYLERTON INT INC
System and Method for Imaging and Treatment of Tumorous Tissue in Breasts Using Computed Tomography and Radiotherapy
InactiveUS20080317202A1Inhibition formationMinimize exposureMaterial analysis using wave/particle radiationRadiation/particle handlingTumour tissueMuscle tissue
The present invention provides a system 10 for irradiating a breast 20 of a patient 22. The system 10 comprises a gantry 12 rotatable about a horizontal axis 14 and comprising a radiation source 16 for generating a radiation beam 18 and a detector 24 spaced from the radiation source 16, and a barrier 26 disposed between the patient 22 and the gantry 12. The barrier 26 is provided with an opening 30 adapted to allow a breast 20 passing therethrough to be exposed to the radiation beam 18. In some embodiments, the barrier 26 is provided with an opening 30 adapted to allow both the breast 20 and the tissue leading from the breast to axilla and the muscle tissue of the adjacent chest wall passing therethrough to be exposed to the radiation beam 18.
Owner:VARIAN MEDICAL SYSTEMS
Implant anchor systems
InactiveUS7204847B1Improve anchoring abilityResists migrationHeart valvesCatheterMuscle tissueBand shape
The present invention provides implant devices configured to become anchored within tissue so that they do not migrate despite experiencing aggressive migration forces applied by the highly dynamic movement of muscle tissue that surrounds them. Additionally, methods for placing the devices so that they remain securely anchored within the tissue are provided. The devices are comprised of a flexible body, preferably formed from a helical wound spring. In a preferred embodiment the spring is wound from a ribbon-like filament having series of barbs or ridges formed along the proximal facing edge of the wound ribbon. The ribbon-like filament may be etched from a flat sheet of material, having barbs formed along one edge. The filament may then be wrapped into a helical coil shape to take the form of an implant having barbs formed along the proximally facing edge of each coil to resist migration.
Owner:CR BARD INC
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