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49444results about "Peptide preparation methods" patented technology

Nucleic acid encoding poly-zinc finger proteins with improved linkers

Polynucleotides encoding chimeric proteins, and methods for their production and use are disclosed. The chimeric proteins comprise a flexible linker between two zinc finger DNA-binding domains, wherein the linker contains eight or more amino acids between the second conserved histidine residue of the carboxy-terminal zinc finger of the first domain and the first conserved cysteine residue of the amino-terminal zinc finger of the second domain.
Owner:MASSACHUSETTS INST OF TECH
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