41 results about "Keratin" patented technology

The invention relates to the technical field of daily chemical and skin external preparations, in particular to a six-dimensional synergistic effect-based acne removal and repair composition, which is prepared from the following active ingredients in parts by weight: 1 to 10 parts of sturgeon caviar extract, 0.1 to 10 parts of chlorogenic acid, 0.1 to 20 parts of 4-tert-butyl cyclohexanol and 0.1 to 20 parts of willow extract. The sturgeon caviar extract is prepared by supercritical CO2 fluid extraction, the willow extract is treated by a synthase process, the content of salicin is not less than 1.5 wt%, and at least one active component in the composition is subjected to supramolecular inclusion modification; the preparation method comprises the following steps: sequentially preparing the extracts and components, sequentially mixing, and finally carrying out an inclusion reaction. The composition constructs a full-link acne removal and skin health maintenance system through a six-dimensional synergistic effect of bacteriostasis, oil control, anti-inflammation, allergy relief, cutin dredging and repairing, has the characteristics of efficient acne removal, mildness, safety and low recurrence rate, is suitable for various skin types such as sensitive acne skin, and can be widely applied to acne removal products of various dosage forms.

The present invention pertains to a multi-part cosmetic composition which has both a physical property providing good adhesion for preventing dripping during mixing at the time of use and during application to keratin tissues such as skin and hair, and a physical property providing ease of spreading after application.　The present invention provides a multi-part cosmetic composition which comprises a plurality of constituent preparations including a preparation I and a preparation II, wherein the preparations I and II each comprise a component (A) that is an ionic surfactant, a component (B) that is a cationic polymer, a component (C) that is a higher alcohol, and a component (D) that is a nonionic surfactant and have different viscosities at least at 30°C, and all of the constituent preparations are mixed together upon use. The viscosity ratio (preparation II / preparation I) of the viscosity of the preparation II at 30°C to the viscosity of the preparation I at 30°C is 3 or more, and the ratio of the shear viscosity a of a mixture prepared by mixing all of the constituent preparations together at a shear rate of 0.0037 S-1 to the shear viscosity b of the mixture at a shear rate of 139 S-1, i.e., (shear viscosity a / shear viscosity b), is 5000 or more when the shear rate is changed from 0.001 S-1 to 1000 S-1 and the shear viscosities are measured with a rheometer at 25°C.

This invention discloses a hoof protein product and its preparation method, belonging to the field of component separation and extraction; using hoof as raw material, the method includes the following steps: (1) hoof pretreatment: the hoof is washed, crushed and sieved to obtain hoof powder (2) subcritical extraction: the hoof powder is taken and pure water containing food-grade acid-base regulator is added, and a reaction solution is prepared by subcritical hydrolysis reaction (3) the reaction solution is centrifuged, separated, dialyzed and dried to obtain hoof protein; the extracted hoof protein is rich in total essential amino acids (more than 40 g / 100g), among which the content of essential amino acids such as histidine, leucine, isoleucine, threonine and cysteine ​​exceeds the content of ideal protein amino acids recommended by WHO / FAO, and has high nutritional value. The essential amino acid index (EAAI), biological value (BV) and nutritional index (NI) are close to the gold standard of egg protein, and the digestibility is high. It has good functional characteristics and has the potential to be a protein supplement component; the preparation process of this invention is scientific and reasonable, easy to operate, low in cost, can realize continuous production, and has no pollution to the environment.

The invention relates to the technical field of crossing of artificial intelligence and intelligent health equipment, and discloses an intelligent comb integrating multi-mode biological feature recognition and a detection method. According to the method, in the daily combing process, five types of biological feature signals including sebum secretion, keratin metabolism, local inflammation, hair physical characteristics and skin barrier integrity are synchronously collected; and after preprocessing, inputting the data into a multi-modal fusion analysis model, generating a multi-dimensional health score through a cross-modal attention mechanism, and triggering risk early warning. The system comprises a comb body structure conforming to ergonomics, a multi-mode sensing array, a signal processing unit, a local storage, a wireless communication and a power supply module, and supports user identity recognition and environment temperature and humidity compensation. According to the application, non-inductive, high-frequency and comprehensive scalp health quantitative monitoring is realized, and the early risk identification capability and the detection robustness are remarkably improved.

The present application relates to a hydrocolloid composition comprising a block copolymer, a plasticizer, a tackifying resin and a viscous polysaccharide. The hydrocolloid composition can be used to prepare a hydrocolloid dressing with higher liquid absorption and tack retention, and can remove old and worn-out keratin on the surface of the skin, and has excellent exfoliation effect.

The present invention pertains to a multi-agent cosmetic composition having both physical properties that exhibit good adhesion for preventing dripping during mixing at the time of use or during application to keratin tissue such as skin or hair, and physical properties that exhibit ease of spreading after the application.　Specifically, the present invention pertains to a multi-agent cosmetic composition that contains the following components (A) an ionic surfactant, (B) a cationic polymer, (C) a higher alcohol, and (D) a nonionic surfactant, that contains a plurality of constituent agents including an agent I and an agent II that have different viscosities at least at 30℃, and that is to be used by mixing all of the constituent agents at the time of use. The viscosity ratio (agent II / agent I) of the viscosity of the agent II at 30°C to the viscosity of the agent I at 30°C is 3 or more, and, in a mixture obtained by mixing all the constituent agents, the ratio (shear viscosity a / shear viscosity b) of the shear viscosity a at a shear rate of 0.0037 S-1 to the shear viscosity b at a shear rate of 139 S-1 measured at 25°C by a rheometer when the shear rate is changed from 0.001 S-1 to 1000 S-1 is 5000 or more.

This invention relates to an anti-hair loss composition, characterized by being a mixture of component A and component B; wherein component A comprises the following components: water, sodium fatty alcohol polyoxyethylene ether sulfate, CAB-35 surfactant, CMT-30B surfactant, ML35 foaming agent, G14S hair conditioning agent, trihydroxystearin, and plum fermentation liquid. Its advantages are that the composition is mild and non-irritating, effectively reducing hair loss and promoting hair growth. Its core relies on the protective effect of silk protein hydrolysate on keratin to prevent breakage and strengthen hair, while plum extract helps control oil and improve the hair growth environment. Simultaneously, the growth-promoting effect of plum extract on hair follicle cells enhances the anti-hair loss effect, while also nourishing the scalp, improving dry and frizzy hair, and enhancing hair smoothness and strength.

The invention relates to relates to eye keratin material coating compositions including water, at least one low glass transition temperature (Tg) film-forming agent, at least one secondary alcohol compound, wherein a weighted average ratio of molecular weight / number of secondary alcohol groups for the at least one secondary alcohol compound present in the composition is less than 69, and optionally at least one nonionic amphiphilic thickening agent, as well as to methods of using such compositions and kits containing such compositions.

The present application belongs to the technical field of exosome application, and discloses an exosome composition, which is obtained by mixing exosomes of Funaria hygrometrica, exosomes of Cnidium monnieri and exosomes of mesenchymal stem cells according to a mass ratio of 2-5:3-8:0.5-1. The exosomes of Funaria hygrometrica can significantly reduce the concentration of inflammatory factors, thereby achieving the effects of inhibiting excessive secretion of sebum and improving pores. The exosomes of Cnidium monnieri also synergize with the exosomes of Funaria hygrometrica to strengthen normal differentiation of keratinocytes, effectively alleviate excessive keratin layer multi-layering caused by excessive secretion of sebum, and thereby inhibit the volume increase of hair follicles. After the exosomes of mesenchymal stem cells and the plant exosomes are combined, the elasticity of the skin can be significantly improved, and the problem of skin laxity can be improved, so that the pores become more delicate, and the pores are significantly reduced in vision. The exosome composition of the present application has the effects of significantly improving coarse pores and increasing skin elasticity, can be made into various product forms, and has a wide application prospect.

BIPHASIC COMPOSITION AND ITS PROCESSES This disclosure relates to a biphasic composition for removing makeup, cleansing, and conditioning a keratin layer, comprising: (i) an aqueous phase comprising: (a) at least one alpha hydroxy acid; (b) at least one poly(hydroxy) acid; (c) at least one brightening active ingredient; (d) at least one anti-dullness active ingredient; and (e) water; and (ii) an oily phase comprising: (f) at least one emollient and (g) optionally at least one antioxidant. Figure for the abstract: none

1. The name of the design product: foot file (GX201). 2. The use of the design product: foot file for removing dead skin, calluses and keratin. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses a softening and exfoliating skin protective agent and a preparation method thereof. According to the invention, the glycerol is matched with two natural oils, namely the simmondsia chinensis seed oil and the camellia seed oil, so that a protective film can be formed on the skin surface, the moisturizing and repairing capabilities are enhanced, and meanwhile, due to the addition of the lecithin, the oils and the water phase are better fused, and the skin-friendly property of the product is improved. Polysaccharide components such as tremella polysaccharide and dendrobe oligosaccharide can further strengthen the skin barrier and help to maintain the healthy state of the cuticle. Various plant extracts are matched, softening, stripping, relieving and repairing are taken into consideration, the willow bark extract and the sugarcane extract are beneficial to mildly promoting metabolism of old and waste cutin and avoiding irritation of traditional stripping components, and the purslane extract and the centella asiatica extract can relieve skin and reduce discomfort possibly occurring in the stripping process. Softening and stripping as well as protection and repair are performed synchronously, and the skin care agent is suitable for scenes requiring improvement of rough cutin and care of delicate skin.

The invention belongs to the technical field of biological medicines, and particularly relates to application of aescin in preparation of a product for inducing autophagy of skin cells. According to the application disclosed by the invention, research finds that aescin can induce autophagy of skin keratinocytes for the first time, and the expression level of autophagy-related proteins LC3-I and LC3-II in the skin keratinocytes can be remarkably improved; in addition, aescin and ursolic acid have a synergistic effect in the aspect of inducing skin keratinocyte autophagy, and are safe and non-irritant to skin. Therefore, the aescin and the composition of the aescin and the ursolic acid can be used for preparing products for inducing autophagy of skin cells so as to resist aging, remove freckles, whiten skin, control oil and strengthen a skin cuticle barrier, and products for slowing down a scleroderma process / relieving a scleroderma symptom, slowing down an atopic dermatitis process / relieving an atopic dermatitis symptom and relieving acne. The traditional Chinese medicine composition has the advantages of remarkable curative effect and high safety.

The application discloses sea cucumber oil and a preparation method and application thereof. The sea cucumber oil is prepared by using sea cucumber intestines as raw materials, and by using 95% ethanol and petroleum ether to soak and extract the sea cucumber oil, and then by using vacuum distillation. By constructing an acute skin ultraviolet radiation damage mouse model, the application verifies for the first time that the sea cucumber oil can effectively relieve the skin redness and keratin layer increase phenomenon caused by ultraviolet radiation, inhibit the ROS rise, reduce the degree of lipid peroxidation of the organism, improve the loss of collagen in the body, regulate the expression of inflammatory factors in the body, up-regulate the expression of the skin Nrf2 gene and the downstream antioxidant gene NQO1, reduce the expression of the negative feedback factor KEAP1, and play an antioxidant role. The sea cucumber oil has high safety, comprehensively and effectively utilizes the waste resources generated in the sea cucumber processing process, and has a good prospect in the cosmetics and medicines for repairing the acute skin light damage after ultraviolet radiation.

The invention discloses an ROS response type acupoint targeting traditional Chinese medicine microneedle patch as well as a preparation method and application thereof, and belongs to the technical field of microneedle patches. In combination with the principles of nasal mucosa physiology, acupoint anatomy and inflammatory pathology, the invention aims to solve the problems of short residence time, low bioavailability and incapability of on-demand administration of the traditional nasal preparation in a minimally invasive and intelligent transmucosal / transdermal administration mode. Aiming at the pathological characteristics that the nasal cavity moist environment, the skin cuticle barrier and the level of local reactive oxygen species (ROS) in the rhinitis attack period are increased, through the combination of the soluble microneedle array and the ROS responsive intelligent material, the precise, long-acting and on-demand release of the medicine at the acupuncture point or mucous membrane targeted part is realized; the painless experience and the treatment compliance of the patient are considered while the curative effect is improved.

The invention relates to skin care products, in particular to mark fading cream for cutin type marks and a preparation method of the mark fading cream. The mark fading cream for the cutin type marks is prepared from the following raw materials in parts by weight: 4-6 parts of nicotinamide, 0.6-1 part of a dragon's blood extract and 0.05-0.15 part of superoxide dismutase, and the unit activity of the superoxide dismutase is greater than or equal to 3000U / g; the superoxide dismutase neutralizes harmful free radicals in the body by using the reducing capacity of the superoxide dismutase, relieves or avoids oxidative damage caused by excessive free radicals, inhibits melanin formation, blocks tyrosinase activity, interferes the biosynthesis process of melanin and reduces deposition of melanin in epidermis; in addition, the superoxide dismutase cooperates with the resina draconis extract and nicotinamide to accelerate skin repair and cuticle renewal.

The invention discloses an animal feather keratin extraction method which comprises the following steps: (1) mixing pretreated animal feathers with a tea saponin solution, and stirring to obtain degreased feathers; mixing the degreased feathers with an ethanol solution, and performing ultrasonic treatment to obtain loose feathers; (2) preparing liquid drops from the water phase and the oil phase through a micro-fluidic chip process, standing and curing the collected liquid drops, demulsifying and cleaning to obtain sodium alginate-CaCl2 microspheres; (3) mixing the loose feathers, water, the sodium alginate-CaCl2 microspheres and keratinase, then adjusting the pH value, and carrying out enzymolysis; finally, taking supernate; and (4) adjusting the pH value of the supernate, precipitating, dialyzing the precipitated mixed solution, and freeze-drying to obtain the animal feather keratin. According to the method disclosed by the invention, the slow release of calcium ions is realized by adding the sodium alginate-CaCl2 microspheres, so that the enzyme utilization rate is improved.

The invention belongs to the technical field of hand and foot nursing, and discloses a non-corrosive body surface cutin hyperplasia nursing patch as well as a preparation method and application thereof. The nursing patch is sequentially provided with a three-layer basic structure including a bacteriostatic functional layer, a flexible substrate and a breathable protective layer from the skin contact side to the outer side, the bacteriostatic functional layer is compounded by clotrimazole, bifonazole and ketoconazole, and the mass ratio of clotrimazole to bifonazole to ketoconazole is (1-2): (1.5-2.5): (0.6-1.5). According to the non-corrosive body surface cutin hyperplasia nursing patch, the root of cutin abnormal hyperplasia is cut off through the antibacterial components, meanwhile, cutin is mildly softened and ablated, and normal skin barriers are not damaged.

To provide a cosmetic composition exhibiting acne-mitigating and keratin-peeling effects as a skin-improving material by the ion pairing of carnitine and salicylate under a weakly acidic condition, and simultaneously mitigating inflammation and erythema as a skin-soothing material.SOLUTION: To provide a cosmetic composition containing carnitine salicylate (CA-SA) as an active ingredient.SELECTED DRAWING: Figure 1-1

This invention discloses a pharmaceutical composition for treating chapped skin caused by tinea pedis and manuum. The composition comprises urea, olive leaf extract, oat alkaloids, and asiaticoside as active ingredients, combined with a hypoallergenic liquid crystal emulsion matrix consisting of shea butter, squalane, caprylic / capric triglycerides, and cetearyl glucoside. This invention utilizes urea to soften keratin and promote crack healing, while simultaneously inhibiting the irritation caused by urea through the synergistic effect of three plant-based anti-inflammatory components, and combining biomimetic oils to repair the skin's lipid barrier. This composition significantly reduces pain and itching at the chapped areas in patients with tinea pedis and manuum, promotes crack closure, and avoids the burning and irritation commonly found in traditional antifungal ointments.

The present disclosure is in the field of dermatological compositions and provides for the use of a composition comprising a semifluorinated alkane to cleanse skin, in particular for the removal of excess sebum or keratin. The disclosure also relates, in particular, to the use of the composition for cleansing skin comprising acne.

The invention provides a composition with oil control and cleaning effects and application thereof. The composition with the oil control and cleaning effects comprises collagen, Himalaya powder salt, walnut shell powder and hydrated silica. The collagen comprises any one or a combination of at least two of a recombinant human source III type collagen, a recombinant human source IV type collagen or a recombinant human source XVII type collagen. The invention creatively finds that the collagen, the Himalaya powder salt, the walnut shell powder and the hydrated silica are matched and have a synergistic effect, so that the effects of adsorbing redundant grease on the skin surface, regulating the skin feeling, removing old and waste cutin, dredging pores and removing grease dirt on the surface layer and pores can be better realized.

1. The name of the design product: foot file (GX209). 2. The use of the design product: foot file for removing dead skin, calluses and keratin on feet. 3. The design points of the design product: in shape. 4. The picture or photo best indicating the design points: perspective view.

The invention discloses a frosted composite particle, a preparation method and application thereof, a frosted composition and a preparation method thereof, and relates to the technical field of exfoliating products, the frosted composite particle comprises an acidic content, and a polylactic acid-glycolic acid copolymer and a cellulose layer sequentially wrapping the acidic content, the mass ratio of the acidic content to the polylactic acid-glycolic acid copolymer to the cellulose layer is 1: (5-25): (14-55); the acidic content comprises an acid stripping agent; the dull polish composite particle can play a role in dull polish, can slowly release acidic substances, is used in an exfoliating product, can effectively remove skin surface cutin and dead skin cells, and the slowly released acid exfoliating agent can soften the skin and reduce the irritation to the skin.

The present application provides a kind of multi-target synergistic whitening and freckle lightening plant composition and its preparation method and application, belong to medical, dental or cosmetic preparation field.The active ingredient is composed of Radix Glycyrrhizae, Radix Scutellariae, Coix Seed, Centella asiatica and mulberry root-bark extract according to specific proportion.The composition realizes signal pathway inhibition, tyrosinase activity blocking, melanin transport interference, keratin metabolism acceleration and skin barrier repair by constructing multi-target synergistic network.The present application overcomes the limitations of single whitening target, such as repeated color spots and slow effect, realizes whole-cycle and systematic whitening and freckle lightening effect under the premise of ensuring safety, and is suitable for cosmetic field.

The invention relates to relates to eye keratin material coating compositions including water, at least one low glass transition temperature (Tg) film-forming agent, at least one nonionic amphiphilic thickening agent, and optionally at least one water-soluble agent selected from the group consisting of polyols, C1-C5 monoalcohols, hydrotropic agent(s), and mixtures thereof, as well as to methods of using such compositions and kits containing such compositions.

1. Name of the product in this design: Double-headed blackhead shovel. 2. Purpose of this product design: To clean pores and remove dead skin and keratin from the face. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

1. Name of the product in this design: Electric foot grinder. 2. Purpose of this design: An electric foot file for foot care, used to remove dead skin, calluses, and keratin from the feet. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.