Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

86 results about "Keratin" patented technology

Keratin (/ˈkɛrətɪn/) is one of a family of fibrous structural proteins. It is the key structural material making up hair, nails, feathers, horns, claws, hooves, and the outer layer of skin. Keratin is also the protein that protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals. The only other biological matter known to approximate the toughness of keratinized tissue is chitin.

High-activity feather hydrolyzed amino acid water-soluble fertilizer and preparation method thereof

The invention relates to a high-activity feather hydrolyzed amino acid water-soluble fertilizer and a preparation method thereof. The preparation method comprises the steps of pretreatment, complex enzyme stepped hydrolysis, nanofiltration separation, chelation and stabilization, spray drying and the like. Feather keratin is hydrolyzed step by step through a compound enzyme, small molecule peptide and amino acid are separated in combination with a nanofiltration membrane, trace elements are added for chelation, and a drying process is optimized, so that the activity and stability of the fertilizer are remarkably improved. The feather keratin can be efficiently degraded, the problem of amino acid racemization caused by a traditional strong acid / alkali method is solved, meanwhile, energy consumption is reduced, and the requirements of modern agriculture for environment-friendly and efficient fertilizer are met.
Owner:JINGMEN XINGUANG BIO ENG CO LTD

Bird's nest acid mild acid brushing composition and application thereof

The invention discloses a sialic acid mild brushing acid composition and application thereof, and relates to the technical field of cosmetics. The sialic acid mild brushing acid composition comprises sialic acid and a solvent, the mass concentration of the sialic acid is 2%-15%, and the solvent is selected from at least one of 1, 3-propylene glycol, butanediol, dipropylene glycol and water. The sialic acid is creatively used as one of the mild brushing acid components, can soften old and waste cutin mildly and promote cutin exfoliation and permeation and absorption of the sialic acid, so that the sialic acid can fully play a skin protection role, has an excellent mild cutin exfoliation effect and has the effects of improving hyperpigmentation and coarse pores; and a dynamic balance skin care strategy of breaking while standing and breaking while standing can be realized. The prepared cosmetics have better moisture retention and safety, repair barriers through moisture retention, improve pigmentation through oxidation resistance, stimulate collagen to remodel a supporting structure to improve coarse pores, and finally consolidate the health state of the skin through immunoregulation.
Owner:BEIJING KANSENBIO TECH CO LTD +1

Acne removing and repairing composition based on six-dimensional synergistic effect

The invention relates to the technical field of daily chemical and skin external preparations, in particular to a six-dimensional synergistic effect-based acne removal and repair composition, which is prepared from the following active ingredients in parts by weight: 1 to 10 parts of sturgeon caviar extract, 0.1 to 10 parts of chlorogenic acid, 0.1 to 20 parts of 4-tert-butyl cyclohexanol and 0.1 to 20 parts of willow extract. The sturgeon caviar extract is prepared by supercritical CO2 fluid extraction, the willow extract is treated by a synthase process, the content of salicin is not less than 1.5 wt%, and at least one active component in the composition is subjected to supramolecular inclusion modification; the preparation method comprises the following steps: sequentially preparing the extracts and components, sequentially mixing, and finally carrying out an inclusion reaction. The composition constructs a full-link acne removal and skin health maintenance system through a six-dimensional synergistic effect of bacteriostasis, oil control, anti-inflammation, allergy relief, cutin dredging and repairing, has the characteristics of efficient acne removal, mildness, safety and low recurrence rate, is suitable for various skin types such as sensitive acne skin, and can be widely applied to acne removal products of various dosage forms.
Owner:BEAUTY GUARD (XIAMEN) BIOTECHNOLOGY CO LTD

Mild and moisturizing base makeup product and preparation method thereof

PendingCN121081317ACosmetic preparationsMake-upFennel extractLactic bacteria
The invention provides a mild and moisturizing base makeup product and a preparation method thereof. The base makeup product is prepared from the following raw materials in parts by weight: 0.5 to 2.0 parts of camellia japonica extract, 0.5 to 2.0 parts of black spore block extract, 0.2 to 1.0 part of crithmum maritimum extract, 3.0 to 8.0 parts of four-dimensional hyaluronic acid slurry, 1.0 to 4.0 parts of film-forming agent, 5.0 to 20.0 parts of toner, 2.0 to 6.0 parts of styrene / butadiene copolymer, 8.0 to 15.0 parts of bionic lipid, 40 to 90 parts of purified water, 0.2 to 0.5 part of pH (Potential of Hydrogen) regulator, 1.5 to 3.0 parts of emulsifier and 0.8 to 1.5 parts of preservative. According to the base makeup product disclosed by the invention, a dynamic moisturizing system is constructed through multiple mechanisms. Wherein the four-dimensional hyaluronic acid slurry is used as a core, and all-around and three-dimensional moisturizing from epidermis water locking, stratum corneum permeation water replenishing to surface water storage is realized through the cooperation of hyaluronic acids with different molecular weights. The bionic lipid simulates a human body sebum film to form a skin-friendly moisturizing barrier, so that water loss is effectively prevented. Meanwhile, the crithmum maritimum extract and the lactobacillus fermentation product can actively repair the skin barrier, and the moisturizing capacity of the skin is further enhanced.
Owner:GUANGZHOU NATURAL BEAUTY COSMETICS CO LTD

Preparation and application of desoxyribonucleic acid and desoxyribonucleic acid derivative transdermal delivery system

The invention relates to preparation and application of a desoxyribonucleic acid and desoxyribonucleic acid derivative transdermal delivery system, and belongs to the technical field of biological medicine and skin care products. Desoxyribonucleic acid and derivatives thereof have the effects of resisting aging, repairing and the like, but are difficult to penetrate through a skin barrier due to large molecular weight and strong polarity. According to the invention, hydroxyethyl chitosan, desoxyribonucleic acid and derivatives thereof are combined through electrostatic interaction to form the nano-composite. The compound is small in particle size and can promote transdermal absorption through hair follicle or cuticle gaps. The preparation method is simple, does not need an auxiliary reagent, and comprises the step of mixing a hydroxyethyl chitosan solution and a deoxyribonucleic acid derivative solution. Experiments show that the compound significantly enhances the transdermal efficiency, and has the effects of promoting cell repair and proliferation and resisting inflammation. The composition can be used for skin care products, and is high in safety and wide in application prospect.
Owner:ZHONGKE HOUPU (GUANGZHOU) TECH DEV CO LTD

Omnibearing anti-acne repairing composition as well as preparation method and application thereof

InactiveCN120713806ACosmetic preparationsAntipyreticCentella asiatica extractRHODOMYRTUS TOMENTOSA FRUIT
The invention relates to the technical field of cosmetics, and particularly discloses an all-directional anti-acne repairing composition as well as a preparation method and application thereof. The comprehensive anti-acne repairing composition is prepared from the following components in parts by weight: 0.01 to 2 parts of flexible salicylic acid, 0.001 to 2 parts of rhodomyrtus tomentosa fruit extract, 0.001 to 0.5 part of quaternary ammonium salt, 0.01 to 5 parts of nicotinamide, 0.001 to 3 parts of herba centellae extract, 0.01 to 3 parts of phellinus linteus extract, 0.0001 to 2 parts of phaeodactylum tricornutum extract and 0.001 to 2 parts of bio-saccharide gum-1. The comprehensive anti-acne repairing composition provided by the invention can resist acnes comprehensively, achieves the effects of removing aged cutin, controlling oil, sterilizing, resisting inflammation, relieving and fading marks and moisturizing, and has a comprehensive repairing effect on various skin injuries including acne skin.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD

Multi-part cosmetic composition, and multi-part hair dyeing or bleaching composition

The present invention pertains to a multi-part cosmetic composition which has both a physical property providing good adhesion for preventing dripping during mixing at the time of use and during application to keratin tissues such as skin and hair, and a physical property providing ease of spreading after application. The present invention provides a multi-part cosmetic composition which comprises a plurality of constituent preparations including a preparation I and a preparation II, wherein the preparations I and II each comprise a component (A) that is an ionic surfactant, a component (B) that is a cationic polymer, a component (C) that is a higher alcohol, and a component (D) that is a nonionic surfactant and have different viscosities at least at 30°C, and all of the constituent preparations are mixed together upon use. The viscosity ratio (preparation II / preparation I) of the viscosity of the preparation II at 30°C to the viscosity of the preparation I at 30°C is 3 or more, and the ratio of the shear viscosity a of a mixture prepared by mixing all of the constituent preparations together at a shear rate of 0.0037 S-1 to the shear viscosity b of the mixture at a shear rate of 139 S-1, i.e., (shear viscosity a / shear viscosity b), is 5000 or more when the shear rate is changed from 0.001 S-1 to 1000 S-1 and the shear viscosities are measured with a rheometer at 25°C.
Owner:KAO CORP

Electric foot grinder (A8)

1. The name of the product under this design: Electric foot grinder (A8). 2. Purpose of this product: This product is used to remove dead skin and keratin from the feet. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.
Owner:深圳市千匠科技有限公司

Foot file (TP-345)

1. The name of the design product: foot file (TP-345). 2. The use of the design product: foot file for removing dead skin, calluses and keratin on feet. 3. The design points of the design product: in shape. 4. The picture or photo best indicating the design points: perspective view 1.
Owner:DONGGUAN I BELIEVE ELECTRONICS APPLIANCE CO LTD

A keratin product and a method for its preparation

PendingCN122356195AEgg proteinFood Preservation Technology
This invention discloses a hoof protein product and its preparation method, belonging to the field of component separation and extraction; using hoof as raw material, the method includes the following steps: (1) hoof pretreatment: the hoof is washed, crushed and sieved to obtain hoof powder (2) subcritical extraction: the hoof powder is taken and pure water containing food-grade acid-base regulator is added, and a reaction solution is prepared by subcritical hydrolysis reaction (3) the reaction solution is centrifuged, separated, dialyzed and dried to obtain hoof protein; the extracted hoof protein is rich in total essential amino acids (more than 40 g / 100g), among which the content of essential amino acids such as histidine, leucine, isoleucine, threonine and cysteine ​​exceeds the content of ideal protein amino acids recommended by WHO / FAO, and has high nutritional value. The essential amino acid index (EAAI), biological value (BV) and nutritional index (NI) are close to the gold standard of egg protein, and the digestibility is high. It has good functional characteristics and has the potential to be a protein supplement component; the preparation process of this invention is scientific and reasonable, easy to operate, low in cost, can realize continuous production, and has no pollution to the environment.
Owner:TIANJIN UNIV OF SCI & TECH

Cuticle care equipment

ActiveCN309526092SCutinNursing care
1. The name of the product under this design: Keratin Care Instrument. 2. Purpose of the product of this design: used for removing dead skin cells, for example. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key points of the design: Design 1 3D drawing. 5. Designate Design 1 as the base design.
Owner:KONINKLIJKE PHILIPS NV

Brightening and firming mask

The invention relates to the technical field of cosmetics, in particular to a brightening and firming mask which comprises mask base cloth and essence, and the essence is composed of functional components and the balance of matrix. Wherein the functional components comprise fine euglena polysaccharide, hydrolyzed collagen, tranexamic acid, hydroxyethyl piperazine ethanesulfonic acid, glutathione and copper peptide. According to the mask provided by the invention, firstly, the euglena gracilis polysaccharide and the hydrolyzed collagen are used for rapidly and synergistically tightening and smoothing the skin from the aspect of physical tightening, and meanwhile, the hydrolyzed collagen can stay in the deep part of the epidermal layer for a long time to promote the synthesis of the collagen so as to bring an endogenous skin tightening effect; then tranexamic acid, glutathione and copper peptide are compounded according to a specific proportion and have a synergistic effect, the activity of tyrosinase is inhibited, and then cutin is mildly stripped through hydroxyethyl piperazine ethanesulfonic acid, so that the functional components rapidly whiten and brighten the skin.
Owner:GUANGZHOU JINHAI YOUPIN BIOTECHNOLOGY CO LTD

Intelligent comb integrating multi-mode biological feature recognition and detection method

The invention relates to the technical field of crossing of artificial intelligence and intelligent health equipment, and discloses an intelligent comb integrating multi-mode biological feature recognition and a detection method. According to the method, in the daily combing process, five types of biological feature signals including sebum secretion, keratin metabolism, local inflammation, hair physical characteristics and skin barrier integrity are synchronously collected; and after preprocessing, inputting the data into a multi-modal fusion analysis model, generating a multi-dimensional health score through a cross-modal attention mechanism, and triggering risk early warning. The system comprises a comb body structure conforming to ergonomics, a multi-mode sensing array, a signal processing unit, a local storage, a wireless communication and a power supply module, and supports user identity recognition and environment temperature and humidity compensation. According to the application, non-inductive, high-frequency and comprehensive scalp health quantitative monitoring is realized, and the early risk identification capability and the detection robustness are remarkably improved.
Owner:DONGGUAN KANGYA PLASTIC HARDWARE CO LTD

Hydrocolloid dressings, methods of manufacture and use

The present application relates to a hydrocolloid composition comprising a block copolymer, a plasticizer, a tackifying resin and a viscous polysaccharide. The hydrocolloid composition can be used to prepare a hydrocolloid dressing with higher liquid absorption and tack retention, and can remove old and worn-out keratin on the surface of the skin, and has excellent exfoliation effect.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

Cinnamomum villosum extraction isolate and application thereof

PendingCN121202752AOrganic active ingredientsOrganic chemistrySinapyl aldehydePlum extract
The invention discloses a partridge extraction isolate and application thereof. According to the present invention, the chemical components of the partridge are researched, such that eight compounds are separated, and the eight compounds are respectively identified as 2-(1H-indol-3-yl) ethyl-tricosanoate (2-(1H-indol-3-yl) ethyl-tricosate) (1), lariciresinol (2), pinoresin (3), syringesin (4), dioscin (5), coniferyl aldehyde (6), syringaldehyde (7) and sinapinalde (8); the compounds are separated from partridge for the first time, the compound (1) is a new compound, the immunomodulatory effect of the compound (1) on mouse splenic lymphocytes is measured, and the result shows that the compound (1) can remarkably induce secretion of TNF-alpha and IL-6, and shows that the compound has immune activation potential equivalent to that of a classical TLR agonist.
Owner:CHANGZHI MEDICAL COLLEGE

Multi-agent cosmetic composition, and multi-agent hair dyeing or bleaching composition

The present invention pertains to a multi-agent cosmetic composition having both physical properties that exhibit good adhesion for preventing dripping during mixing at the time of use or during application to keratin tissue such as skin or hair, and physical properties that exhibit ease of spreading after the application. Specifically, the present invention pertains to a multi-agent cosmetic composition that contains the following components (A) an ionic surfactant, (B) a cationic polymer, (C) a higher alcohol, and (D) a nonionic surfactant, that contains a plurality of constituent agents including an agent I and an agent II that have different viscosities at least at 30℃, and that is to be used by mixing all of the constituent agents at the time of use. The viscosity ratio (agent II / agent I) of the viscosity of the agent II at 30°C to the viscosity of the agent I at 30°C is 3 or more, and, in a mixture obtained by mixing all the constituent agents, the ratio (shear viscosity a / shear viscosity b) of the shear viscosity a at a shear rate of 0.0037 S-1 to the shear viscosity b at a shear rate of 139 S-1 measured at 25°C by a rheometer when the shear rate is changed from 0.001 S-1 to 1000 S-1 is 5000 or more.
Owner:KAO CORP

A hair loss prevention composition and method of making the same

PendingCN122272458ATRIHYDROXYSTEARINActive agent
This invention relates to an anti-hair loss composition, characterized by being a mixture of component A and component B; wherein component A comprises the following components: water, sodium fatty alcohol polyoxyethylene ether sulfate, CAB-35 surfactant, CMT-30B surfactant, ML35 foaming agent, G14S hair conditioning agent, trihydroxystearin, and plum fermentation liquid. Its advantages are that the composition is mild and non-irritating, effectively reducing hair loss and promoting hair growth. Its core relies on the protective effect of silk protein hydrolysate on keratin to prevent breakage and strengthen hair, while plum extract helps control oil and improve the hair growth environment. Simultaneously, the growth-promoting effect of plum extract on hair follicle cells enhances the anti-hair loss effect, while also nourishing the scalp, improving dry and frizzy hair, and enhancing hair smoothness and strength.
Owner:SHUNDE POLYTECHNIC

Degradable chemical descaling patch and preparation method thereof

The invention relates to the technical field of external patches, and discloses a degradable chemical descaling patch and a preparation method thereof, the structure of the degradable chemical descaling patch sequentially comprises a backing layer, a functional matrix layer and a bonding layer; the functional matrix layer is of a double-layer structure and comprises a reservoir layer tightly attached to the backing layer, the reservoir layer comprises a first hydrogel matrix and a pH response microcapsule dispersed in the first hydrogel matrix, and a core substance of the pH response microcapsule is a compound containing a first keratin exfoliating agent with the mass concentration of 30-40%; the hydration layer is arranged between the reservoir layer and the bonding layer and comprises a second hydrogel matrix and a second keratin exfoliating agent with the mass concentration of 5-10%, and the second keratin exfoliating agent is dispersed in the second hydrogel matrix. Through the design of function partitioning and time sequence partitioning, the potential irritation of the product in the initial stage of use is remarkably reduced, and the technical problem that powerful active matter and mildness are difficult to consider at the same time is solved.
Owner:倪小贤

Eye keratin material coating compositions

The invention relates to relates to eye keratin material coating compositions including water, at least one low glass transition temperature (Tg) film-forming agent, at least one secondary alcohol compound, wherein a weighted average ratio of molecular weight / number of secondary alcohol groups for the at least one secondary alcohol compound present in the composition is less than 69, and optionally at least one nonionic amphiphilic thickening agent, as well as to methods of using such compositions and kits containing such compositions.
Owner:LOREAL SA

A hair pore cleaning composition containing phellinus baumii and a preparation method and application thereof

The application discloses a pore cleaning composition containing phellinus baumii, and a preparation method and application thereof, and belongs to the technical field of cosmetics. The pore cleaning composition provided by the application comprises the following components in mass fraction: bidirectional fermentation product 0.1-10 parts, guaiacum extract 0.1-5 parts, hydroxyl asiaticoside 0.01-1 part, coffee arabica seed extract 0.01-3 parts, and sophoramine 0.01-2 parts. The bidirectional fermentation product is a bidirectional fermentation product of phellinus baumii and lactobacillus plantarum. The application can inhibit sebum oxidation, prevent keratin accumulation, resist inflammation, kill bacteria and the like through the cooperation of the components in the application, so that the blackheads and whiteheads can be reduced quickly and long-acting, and the effect of shrinking pores can be achieved. Meanwhile, the pore cleaning composition provided by the application is mild and non-irritating, and is especially suitable for people with sensitive skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Exosome composition and its use in improving pores

The present application belongs to the technical field of exosome application, and discloses an exosome composition, which is obtained by mixing exosomes of Funaria hygrometrica, exosomes of Cnidium monnieri and exosomes of mesenchymal stem cells according to a mass ratio of 2-5:3-8:0.5-1. The exosomes of Funaria hygrometrica can significantly reduce the concentration of inflammatory factors, thereby achieving the effects of inhibiting excessive secretion of sebum and improving pores. The exosomes of Cnidium monnieri also synergize with the exosomes of Funaria hygrometrica to strengthen normal differentiation of keratinocytes, effectively alleviate excessive keratin layer multi-layering caused by excessive secretion of sebum, and thereby inhibit the volume increase of hair follicles. After the exosomes of mesenchymal stem cells and the plant exosomes are combined, the elasticity of the skin can be significantly improved, and the problem of skin laxity can be improved, so that the pores become more delicate, and the pores are significantly reduced in vision. The exosome composition of the present application has the effects of significantly improving coarse pores and increasing skin elasticity, can be made into various product forms, and has a wide application prospect.
Owner:GUANGDONG AIE BIOSCIENCE CO LTD

BIPHASIC COMPOSITION AND ITS PROCESSES

BIPHASIC COMPOSITION AND ITS PROCESSES This disclosure relates to a biphasic composition for removing makeup, cleansing, and conditioning a keratin layer, comprising: (i) an aqueous phase comprising: (a) at least one alpha hydroxy acid; (b) at least one poly(hydroxy) acid; (c) at least one brightening active ingredient; (d) at least one anti-dullness active ingredient; and (e) water; and (ii) an oily phase comprising: (f) at least one emollient and (g) optionally at least one antioxidant. Figure for the abstract: none
Owner:LOREAL SA

Compound antibacterial nail cream containing hanfengji cream and binding therapy of compound antibacterial nail cream containing hanfengji cream

The invention discloses a compound antibacterial nail cream containing hanghai cream and a binding therapy thereof, and relates to the technical field of dermatological external preparations, the compound antibacterial nail cream comprises active components and a matrix, the active components comprise, by weight, 10%-20% of hanghai powder, 5%-10% of salicylic acid, 5%-10% of benzoic acid, 5%-10% of boric acid, 10%-20% of talcum powder and 5%-8% of carbamide, and the matrix is prepared from, by weight, 20%-30% of water. Components with different effects are combined, and salicylic acid, benzoic acid and carbamide cooperate to jointly achieve the effects of softening and exfoliating sick nail cutin; and meanwhile, through the mutual cooperation of the buddleja officinalis powder, the boric acid and the components, the growth of microorganisms can be inhibited. In addition, the base material formed by the vaseline and the liquid paraffin can enable the ointment body to keep a proper ointment form, and is convenient to smear and attach. The application method comprises the following steps of: grinding a diseased nail, applying the ointment and binding, so that the active ingredients can be promoted to permeate into a nail bed.
Owner:松阳县实瑞生物科技服务部(个人独资)

Foot file (GX201)

1. The name of the design product: foot file (GX201). 2. The use of the design product: foot file for removing dead skin, calluses and keratin. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.
Owner:高智贤

Softening and exfoliating skin protective agent and preparation method thereof

The invention discloses a softening and exfoliating skin protective agent and a preparation method thereof. According to the invention, the glycerol is matched with two natural oils, namely the simmondsia chinensis seed oil and the camellia seed oil, so that a protective film can be formed on the skin surface, the moisturizing and repairing capabilities are enhanced, and meanwhile, due to the addition of the lecithin, the oils and the water phase are better fused, and the skin-friendly property of the product is improved. Polysaccharide components such as tremella polysaccharide and dendrobe oligosaccharide can further strengthen the skin barrier and help to maintain the healthy state of the cuticle. Various plant extracts are matched, softening, stripping, relieving and repairing are taken into consideration, the willow bark extract and the sugarcane extract are beneficial to mildly promoting metabolism of old and waste cutin and avoiding irritation of traditional stripping components, and the purslane extract and the centella asiatica extract can relieve skin and reduce discomfort possibly occurring in the stripping process. Softening and stripping as well as protection and repair are performed synchronously, and the skin care agent is suitable for scenes requiring improvement of rough cutin and care of delicate skin.
Owner:HUNAN PIYE SHUANG MEDICAL TECHNOLOGY CO LTD

Application of aescin in preparation of products for inducing autophagy of skin cells

The invention belongs to the technical field of biological medicines, and particularly relates to application of aescin in preparation of a product for inducing autophagy of skin cells. According to the application disclosed by the invention, research finds that aescin can induce autophagy of skin keratinocytes for the first time, and the expression level of autophagy-related proteins LC3-I and LC3-II in the skin keratinocytes can be remarkably improved; in addition, aescin and ursolic acid have a synergistic effect in the aspect of inducing skin keratinocyte autophagy, and are safe and non-irritant to skin. Therefore, the aescin and the composition of the aescin and the ursolic acid can be used for preparing products for inducing autophagy of skin cells so as to resist aging, remove freckles, whiten skin, control oil and strengthen a skin cuticle barrier, and products for slowing down a scleroderma process / relieving a scleroderma symptom, slowing down an atopic dermatitis process / relieving an atopic dermatitis symptom and relieving acne. The traditional Chinese medicine composition has the advantages of remarkable curative effect and high safety.
Owner:TIANJIN UNIV OF SCI & TECH +1

Sea cucumber oil and preparation method and application thereof

The application discloses sea cucumber oil and a preparation method and application thereof. The sea cucumber oil is prepared by using sea cucumber intestines as raw materials, and by using 95% ethanol and petroleum ether to soak and extract the sea cucumber oil, and then by using vacuum distillation. By constructing an acute skin ultraviolet radiation damage mouse model, the application verifies for the first time that the sea cucumber oil can effectively relieve the skin redness and keratin layer increase phenomenon caused by ultraviolet radiation, inhibit the ROS rise, reduce the degree of lipid peroxidation of the organism, improve the loss of collagen in the body, regulate the expression of inflammatory factors in the body, up-regulate the expression of the skin Nrf2 gene and the downstream antioxidant gene NQO1, reduce the expression of the negative feedback factor KEAP1, and play an antioxidant role. The sea cucumber oil has high safety, comprehensively and effectively utilizes the waste resources generated in the sea cucumber processing process, and has a good prospect in the cosmetics and medicines for repairing the acute skin light damage after ultraviolet radiation.
Owner:FIRST INSTITUTE OF OCEANOGRAPHY MNR