1029 results about "Shear rate" patented technology

Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include corticosteroid component-containing particles present in a therapeutically effective amount, a viscosity inducing component, and an aqueous carrier component. The compositions have viscosities of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity is in the range of from about 140,000 cps to about 300,000 cps. The compositions advantageously suspend the particles for prolonged periods of time.

Aphron-containing spotting fluids and their use in releasing pipe or tools stuck in the filter cake on the sides of a borehole are disclosed. The spotting fluids comprise a liquid, either aqueous, oleaginous, or mixtures thereof, a viscosifier which imparts a low shear rate viscosity to the fluids of at least 10,000 centipoise, an aphron-generating surfactant, and aphrons. The spotting fluids are used in a conventional method of releasing pipes or tools stuck in the filter cake on the sides of a borehole during conventional drilling or well servicing operations.

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10⁻⁷ reciprocal second.

Injection molding systems and methods useful for making microcellular foamed materials are provided as well as microcellular articles. Pressure drop rate and shear rate are important features in some embodiments, and the invention provides systems for controlling these parameters in an injection molding system. Another aspect involves an injection molding system including a nucleator that is upstream of a pressurized mold. Another aspect involves an extrusion system with the reciprocating screw for forming a single phase solution of non-nucleated blowing agent and polymeric material. Another aspect involves very thin walled microcellular material and very thin walled polymeric material. Another aspect provides a method for producing high weight reductions in very thin-walled parts with surfaces that have no noticeable differences from non-foamed parts.

A spiral microchannel particle separator includes an inlet for receiving a solution containing particles, at least two outlets, and a microchannel arranged in a plurality of loops. Particles within a solution flowing through the spiral microchannel experience a lift force F_L and a Dean drag force F_D. The spiral radius of curvature R and the hydraulic diameter D_h of the spiral microchannel are such that for a flow rate U of the solution, the lift force F_L and a Dean drag force F_D are approximately equal and act in opposite directions for particles of a first size. The particles of the first size are focused in a single stream located at an equilibrium position near an inner wall of the microchannel. In another embodiment, a straight microchannel particle separator separates particles by modulating shear rates via high aspect ratios that focuses particles of a first size along two first walls.

This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10⁻⁷ reciprocal second.

A method for forming biodegradable fibers is provided. The method includes blending polylactic acid with a polyepoxide modifier to form a thermoplastic composition, extruding the thermoplastic composition through a die, and thereafter passing the extruded composition through a die to form a fiber. Without intending to be limited by theory, it is believed that the polyepoxide modifier reacts with the polylactic acid and results in branching of its polymer backbone, thereby improving its melt strength and stability during fiber spinning without significantly reducing glass transition temperature. The reaction-induced branching can also increase molecular weight, which may lead to improved fiber ductility and the ability to better dissipate energy when subjected to an elongation force. To minimize premature reaction, the polylactic acid and polyepoxide modifier are first blended together at a relatively low temperature(s). Nevertheless, a relatively high shear rate may be employed during blending to induce chain scission of the polylactic acid backbone, thereby making more hydroxyl and/or carboxyl groups available for subsequent reaction with the polyepoxide modifier. Once blended, the temperature(s) employed during extrusion of the blended composition can be selected to both melt the composition and initiate a reaction of the polyepoxide modifier with hydroxyl and/or carboxyl groups of the polylactic acid. Through selective control over this method, the present inventors have discovered that the resulting fibers may exhibit good mechanical properties, both during and after melt spinning.

The invention is directed to chalcogenide glasses suitable for use in plastics forming processes. The glasses have the general formula YZ, where Y is Ge, As, Sb or a mixture of two or more of the same; Z is S, Se, Te, or a mixture of two or more of the same; and Y and Z are present in amounts (in atomic/element percent) in the range of Y=15–70% and Z=30–85%. The chalcogenide glasses of the invention have a 10,000 poise temperature of 400° C. and are resistant to crystallization when processed at high shear rates at their 10,000 poise temperature. The glasses can be used to make, among other items, molded telecommunication elements, lenses and infrared sensing devices.

Anti-angiogenesis compositions, and methods of using such compositions, useful for intraocular to treat neovascularization. The compositions can have viscosities at about 25° C. of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity at 25° C. is in the range of from about 80,000 cps to about 300,000 cps.

A resin composition exhibiting excellent antistaticity and static charge dissipating performance and having extremely small variations of antistatic properties (saturated static voltage and half-life period of static voltage) on the surface of a molded article and a transportation jig for electronic field made of the above resin composition are provided by using a resin composition produced by compounding (A) 100 parts by weight of a thermoplastic resin with (B) 1 to 30 parts by weight of a carbon fiber having a diameter of 1 nm to 1 mum, a length of 1 mum to 3 mm and a volume resistivity of smaller than 1 OMEGAcm and (C) 5 to 200 parts by weight of an antistatic polymer having a surface resistivity of 108 to 1011OMEGA (measured under impressed voltage of 500V), a melting point of 100° C. or above, an apparent melt viscosity of 10 to 1,000 Pa.s at apparent shear rate of 1,000 sec-1 at 260° C. and an apparent melt viscosity ratio of the antistatic polymer to the thermoplastic resin of 0.01 to 1.3 under the above condition.

The invention provides a stretch blow molded container formed from a thermoplastic resin material which comprises polyglycolic acid having (a) a repeating unit represented by the following formula (1): (b) a melt viscosity, eta * [as measured at a temperature of (the melting point, Tm of the polymer+20 DEG C.) and a shear rate of 100/sec] of 500-100,000 Pa.s; (c) a melting point, Tm of at least 180 DEG C.; (d) a melt enthalpy, DELTA Hm of at least 20 J/g; and (e) a density of at least 1.50 g/cm3 as measured in an unoriented, crystallized form, wherein the stretch blow molded container has tensile strength (in a circumferential direction) of at least 100 MPa and a carbon dioxide permeability (as measured at a temperature of 23 DEG C. and 80% relative humidity; in terms of the thickness of 50 mu m) of 300 cc/m2.day.atm or smaller at the body sidewall thereof, and a production process thereof.

A storable suspension for the treatment of a subterranean formation contains an ultra lightweight (ULW) particulate and a carrier fluid of xanthan gum or a xanthan variant, a polysaccharide and water. The suspension exhibits a high viscosity at low shear rates and does not appear to separate for at least one week. The weight ratio of polysaccharide:xanthan in the storable suspension is between from about 8:1 to about 1:8. Prior to introducing the suspension into the formation, a foaming agent may be added, preferably in an amount sufficient to render a foam quality between from about 30 to about 98.

The invention provides a method for forming polymer microrods, the method including the steps of providing a polymer solution comprising a polymer dissolved in a first solvent; providing a dispersion medium comprising a second solvent, wherein the first solvent and the second solvent are miscible or partially soluble in each other, and wherein the polymer is insoluble in the second solvent; adding the polymer solution to the dispersion medium to form a dispersed phase of polymer solution droplets within the dispersion medium; and introducing a shear stress to the dispersion medium and dispersed polymer solution droplets for a time and at a shear rate sufficient to elongate the polymer solution droplets to form microrods and solidify the microrods by attrition of the polymer solvent into the dispersion medium.

A method for forming a biodegradable polylactic acid suitable for use in fibers is provided. Specifically, a polylactic acid is melt processed at a controlled water content to initiate a hydrolysis reaction. Without intending to be limited by theory, it is believed that the hydroxyl groups present in water are capable of attacking the ester linkage of polylactic acids, thereby leading to chain scission or “depolymerization” of the polylactic acid molecule into one or more shorter ester chains. The shorter chains may include polylactic acids, as well as minor portions of lactic acid monomers or oligomers, and combinations of any of the foregoing. By selectively controlling the hydrolysis conditions (e.g., moisture and polymer concentrations, temperature, shear rate, etc.), a hydrolytically degraded polylactic acid may be achieved that has a molecular weight lower than the starting polymer. Such lower molecular weight polymers have a higher melt flow rate and lower apparent viscosity, which are useful in a wide variety of fiber forming applications, such as in the meltblowing of nonwoven webs.

The present invention relates to a method for the treatment and/or prevention of overweight in a monogastric mammal. More particularly, the invention is concerned with such a method comprising administering to the mammal a liquid edible composition with a pH of more than 5, a viscosity below 50 mPas at a shear rate of 100 s-1 and 20° C., and a viscosity of at least 125% of the aforementioned viscosity at a pH 3 and a temperature of 37° C.; and with a caloric density between 0 and 500 kcal per liter, the composition comprising: c. between 0.01 and 5 wt. % of one or more polysaccharides selected from the group consisting of pectin and alginate; and between 0.01 and 3 wt. % calcium

Provided is a method for producing a polyester film, including: subjecting a polyester raw material resin, which contains a titanium compound and has an intrinsic viscosity of from 0.71 to 1.00, to melt extrusion using a twin-screw extruder which includes a cylinder; two screws disposed inside the cylinder; and a kneading disk unit disposed in at least a portion of a region extending from a 10%-position to a 65%-position of screw length with respect to an upstream end of the screws in a resin extrusion direction as a starting point, at a maximum shear rate generated inside the twin-screw extruder of from 10 sec⁻¹ to 2000 sec⁻¹;

• • forming an unstretched film by cooling and solidifying the melt extruded polyester resin on a cast roll; subjecting the unstretched film to biaxial stretching in a longitudinal direction and a lateral direction; and heat fixing the stretched film formed by biaxial stretching.

The invention relates to a method using three-dimensional mechanics characteristics and tissue specific imaging of blood vessels and plaques for detection. The method is on the basis of a multi-beam focus wave and superfast plane wave alternative transmitting sequence and can also be extended to a line-by-line scan imaging manner; the forms and the functions of the blood vessels and the plaques are evaluated and imaged respectively from the aspects of the radial-direction, circumferential and axial-direction three-dimensional mechanics characteristics, blood vessel wall shear rate, plaque form and tissue characterization, and the like; the new method which is provided for detection of the vulnerable plaques of a carotid artery is regarded as the improvement of the existing method.