3050 results about "Oligomer" patented technology

This disclosure relates to dimeric immunotherapeutics that comprise two IgGs that are crosslinked with a disulfide bond. The two IgGs may be chimeras of two different heavy chains, in which one heavy chain includes a cysteine mutation that forms the disulfide bond, and the other heavy chain lacks the cysteine mutation. The presence of a cysteine mutation in only one of the heavy chains of an IgG avoids two disulfide bonds between the two IgGs, which increases the accessible orientations between the two crosslinked IgGs, and also avoids the formation of trimers and higher-order oligomers.

The invention relates to the technical field of high polymer materials, and particularly provides a self-repairing type UV curing alumite color layer coating and a preparation method thereof. The water-based ink is prepared from, by weight, 30-50 parts of polyurethane acrylic resin, 10-25 parts of modified acrylic oligomer containing dynamic covalent bonds, 2-5 parts of photoinitiator, 3-8 parts of hydrophobic modified nano filler and 1-3 parts of cross-linking agent, and the dynamic covalent bonds are selected from at least one of hydrazide bonds, boric acid ester bonds and Diels-Alder bonds. By introducing a gradient energy collaborative network of dynamic covalent bonds and quadruple hydrogen bonds, rapid self-repairing of the coating at normal temperature and thermal triggering recombination of deep damage are achieved, and meanwhile through the micro-phase separation design of the hydrophobic core-shell filler and the graft modified silicon carbide nanowires, the hydrolysis resistance is improved.

The invention discloses low-migration UV ink-jet ink and a preparation method thereof, and belongs to the technical field of novel ink. Comprising the following components in parts by mass: 10-15 parts of a dynamic cross-linked polyurethane acrylate oligomer, 5-8 parts of an epoxy silicone resin oligomer, 2-3 parts of modified silicon dioxide, 4-5 parts of a photoinitiator, 15-20 parts of sorbic acid modified color paste, 1-2 parts of nano cerium oxide and 0.5-1 part of an antioxidant. The molecular chain of the dynamic cross-linked polyurethane acrylate oligomer prepared by the invention contains an active group capable of forming a cross-linked structure and a dynamic covalent bond. The groups and bonds promote molecular chain crosslinking when the ink is cured, a three-dimensional network is formed, and the molecular crosslinking density is improved. Through interaction of palmitic acid modified silicon dioxide and oligomer, the palmitic acid modified silicon dioxide is uniformly dispersed in a matrix and interferes molecular chain movement during curing, so that the crosslinking density is further improved, an ink film layer is more compact and firmer, the wear resistance and the scratch resistance are improved, and the tinting strength and the stability are indirectly enhanced.

The invention discloses a rational copolymerization strategy for improving the stability of an oligomeric structure of acid-induced high-order oligomeric decarboxylase AdiA in a neutral to alkaline environment and application of the rational copolymerization strategy, and belongs to the field of bioengineering. According to the strategy, rational charge overturning transformation is carried out on a pentamer radial oligomeric interface and a dimer weft-wise oligomeric interface at the same time, and stable assembly and efficient catalysis of a decamer under the condition that the pH value is from 7.0 to 9.0 from neutral to alkaline are achieved. Wherein positive charges are introduced into a meridian interface to weaken electrostatic repulsion, and negative charges are introduced into a latitudinal interface to enhance dimer compactness and substrate transfer efficiency. The specific enzyme activity of the representative double mutant AdiAD471K / E467K / H736E is 45.5 times that of a wild type when the pH value is 8.0, and the representative double mutant AdiAD471K / E467K / H736E keeps a complete decamer state when the pH value is 7.0-9.0. The yield of butanediamine is up to 156.5 g / L by using the mutant to catalyze whole cells.

The invention discloses a high-refractive-index nano-composite optical adhesive and a preparation method thereof, and belongs to the technical field of optical transparent adhesives. The optical adhesive is prepared by taking a polyurethane acrylate oligomer with a specific structure as matrix resin, introducing surface-modified barium titanate and zirconium oxide core-shell nanoparticles as a functional filler, and matching with an active diluent, a photoinitiator and a silane coupling agent in a specific proportion. Through the design of the core-shell structure, the core problems that the high-refractive-index nanoparticles are easy to agglomerate in an organic resin matrix, the dispersion stability is poor and the bonding force with a matrix interface is weak are effectively solved. The prepared optical adhesive has a refractive index of more than 1.65, a light transmittance of more than 99% and a haze of less than 0.3% after being cured, has excellent bonding strength, weather resistance and long-term use stability, and is especially suitable for precise lamination of high-end display devices (such as OLEDs (Organic Light Emitting Diodes) and micro-lens arrays).

The invention relates to a heat-resistant, water-resistant and flame-retardant backboard composite material as well as a preparation method and application thereof. The heat-resistant, water-resistant and flame-retardant backboard composite material comprises a phosphorus-containing epoxy acrylate oligomer, common epoxy resin, toughened epoxy resin, phosphorus-containing epoxy resin, a filler, an additive flame retardant, a dicyandiamide curing agent, an accelerant, nitrogen-containing phenolic resin, a latent curing agent, a UV absorbent and an antioxidant. The phosphorus content in the material is improved by synthesizing the phosphorus-containing epoxy acrylate oligomer, so that the flame retardant property of the product is improved, and the problem of low flame retardant efficiency caused by direct addition of a phosphorus flame retardant is solved.

The invention belongs to the technical field of coatings, and discloses an anti-sinking water-based acrylic resin coating and a preparation method thereof.The anti-sinking water-based acrylic resin coating is prepared from, by weight, 110-130 parts of modified water-based acrylic resin, 10-25 parts of modified cellulose nanocrystals, 3-5 parts of a composite additive, 4-6 parts of a dispersing agent, 0.5-2 parts of a defoaming agent, 0.5-2 parts of a flatting agent and 10-20 parts of water; the acrylic resin is modified by using the organic silicon oligomer and the epoxy resin, the film hardness is high, the adhesive force is strong, and the film hardness, the impact resistance, the ultraviolet aging resistance and the flame retardant property of the material are improved by adding the modified cellulose nanocrystals and the composite additive.

The invention relates to the technical field of pouring sealant coatings, in particular to a two-component polyurethane circuit board pouring sealant and a preparation method thereof. Comprising a component A and a component B. The component A comprises liquefied MDI, a phosphate flame retardant and a plasticizer. The component B comprises a hydroxyl acrylate oligomer, bio-based polyol, a defoaming agent and a catalyst, the viscosity of the hydroxyl acrylate oligomer at the temperature of 25 DEG C is 8000-15000 mPa.s, and the hydroxyl value of the hydroxyl acrylate oligomer is 100-150 mgKOH / g. The viscosity of the hydroxyl acrylate oligomer at 25 DEG C is limited to be 8000-12000 mPa.s, and the hydroxyl value is 100-140 mgKOH / g, so that the mechanical properties and aging resistance of the pouring sealant can be improved at the same time.

The invention provides a high-hydrophobicity anti-pollution flashover coating and a preparation method thereof, and relates to the field of coatings. The silicone rubber composition is prepared from the following raw materials in parts by weight: 80 to 100 parts of hydroxyl-terminated polydimethylsiloxane; 5 to 15 parts of modified nano silicon dioxide; 10 to 30 parts of a composite self-repairing microcapsule; 10 to 25 parts of a flame retardant; 3-8 parts of a cross-linking agent; 0.5-2 parts of a catalyst; 1-5 parts of an accelerant; 40 to 100 parts of a solvent; the modified nano silicon dioxide is fumed silica subjected to surface treatment by a fluorine-containing silane coupling agent and a platinum catalyst; the capsule wall of the composite self-repairing microcapsule is a polylactic acid-glycolic acid copolymer, and the capsule core of the composite self-repairing microcapsule is a mixed solution of a hydroxyl-terminated polydimethylsiloxane oligomer and methyltris (methylethylketoximino) silane. The coating has excellent hydrophobicity, weather resistance and targeted repair function.

The invention belongs to the technical field of analysis and detection, and discloses a method for detecting perfluorinated and polyfluoroalkyl substances in cosmetics, which comprises the following steps: (1) mixing a perfluorinated and polyfluoroalkyl substance standard solution and an isotope internal standard solution to obtain a mixed standard solution; detecting the mixed standard solution by adopting a liquid chromatograph-mass spectrometer, drawing a standard curve, and calculating to obtain a linear equation; (2) mixing a cosmetic sample with the isotope internal standard solution, adding an extracting solution, extracting, and filtering to obtain a mixed solution to be detected; detecting the mixed to-be-detected solution by adopting the liquid chromatograph-mass spectrometer to obtain a detection result, and substituting the detection result into the linear equation to obtain the content of the perfluoro and polyfluoroalkyl substances in the mixed to-be-detected solution, the perfluoro and polyfluoroalkyl substances comprise perfluorocarboxylic acid, perfluorosulfonic acid, a fluorine polymer, perfluoroalkyl ether sulfonic acid, saturated fluorine telomere acid and perfluoroether carboxylic acid.

The invention provides a spirocyclic expansion monomer, a preparation method thereof and a resin composition. The structural formula of the spirocyclic expansion monomer is as shown in formula I in the specification. The spiro expansion monomer has the advantages of high reaction activity, low shrinkage rate, good compatibility and the like, and the curing volume shrinkage rate of epoxy resin can be reduced through the ring opening effect of the spiro monomer after the spiro expansion monomer is added into an epoxy resin system, so that the curing shrinkage stress is reduced. The invention also provides a resin composition. The resin composition comprises epoxy resin and the spiro-expansive monomer and / or the oligomer of the spiro-expansive monomer. The spiro expansion monomer is applied to an epoxy resin system to prepare a precise fixing adhesive, the shrinkage rate of the adhesive in the curing process can be effectively reduced, so that the curing shrinkage stress is reduced, the coupling precision is improved, and the spiro expansion monomer is mainly applied to the fields of electronic component bonding, optical device bonding and fixing and the like.

The invention belongs to the field of UV glue, and relates to UV ink-jet glue as well as a preparation method and application thereof. The UV ink-jet glue contains an acrylate monomer, a hydrogenated polybutadiene modified acrylate oligomer, an anhydride modified acrylate oligomer, an adhesion promoter, a photoinitiator and an optional auxiliary agent, wherein the acrylate monomer at least contains an allyl hydrogen-containing acrylate monomer. The UV ink-jet glue provided by the invention is low in viscosity, can be applied to each position of a battery cell shell in an ink-jet manner, and after being irradiated and cured by a specific UV light source, double bonds in wet glue react, molecular chains capable of freely moving are mutually cross-linked and combined, the curing speed is high, the surface hardness is high, and the liquid glue is cured into a solid glue film; the adhesive film has extremely strong environmental aging resistance (salt mist resistance, heat and humidity resistance and the like) and electrolyte resistance effects, and can meet the application requirements of power batteries and energy storage batteries at the present stage.

The invention discloses a preparation method of a lignin-based aqueous polyurethane emulsion. The raw materials of the lignin-based aqueous polyurethane emulsion include lignin, oligomeric polyols, polyisocyanates, hydrophilic chain extenders, polyol compounds, organic solvents, etc. In order to solve the disadvantages of traditional aqueous polyurethanes such as poor mechanical properties, poor water resistance, and poor anti-aging ability, the invention compositely blends a certain amount of lignin with polyols, and controls the prepolymerization time through process optimization, so that lignin reacts with isocyanate to form a certain cross-linked structure, greatly improving the mechanical properties and water resistance of the aqueous polyurethane on the premise of ensuring the stability of the emulsion; the invention not only prepares a novel lignin-based aqueous polyurethane emulsion with functional characteristics such as stability, low cost, environmental friendliness, high mechanics, anti-ultraviolet, antibacterial, and hydrophobicity, but also realizes the high-value utilization of lignin as a renewable resource.

The invention relates to the technical field of protective glue, in particular to extreme high and low temperature impact resistant UV (ultraviolet) photocuring electronic protective glue which is prepared from the following raw materials in parts by weight: 30-50 parts of synergistically modified epoxy-urethane acrylate oligomer, 20-35 parts of composite active monomer, 1.5-5 parts of composite photoinitiator and 10-20 parts of core-shell structure inorganic composite filler, 0.6 to 2.2 parts of a silane coupling agent, 0.12 to 1.1 parts of an antioxidant and 0.11 to 1 part of a leveling agent; the preparation method of the synergistically modified epoxy-urethane acrylate oligomer comprises the following steps: reacting resin acid modified epoxy resin with phosphoric acid di (hydroxyethyl acrylate) ester at 80-90 DEG C, and introducing a phosphate group to obtain a phosphate modified epoxy acrylate intermediate; the protection glue unifies rigidity, flexibility and flame retardance on the molecular level through the cooperation of the hybrid oligomer and the core-shell filler, realizes high heat conductivity, strong adhesion and extremely low internal stress, and has extreme temperature impact resistance, long-term damp-heat aging resistance and high-reliability protection performance.

The invention provides a bio-based light-cured heat-conducting and insulating composite material, a preparation method and application, and relates to the technical field of radiation curing, and the bio-based light-cured heat-conducting and insulating composite material comprises a bio-based oligomer, a reactive diluent, a modified heat-conducting filler, a free radical photoinitiator and an organic silicon defoaming agent. The bio-based oligomer is selected as a main component of the photocuring coating, and compared with a coating prepared from petroleum-based acrylic resin in the prior art, the coating has the green and environment-friendly functions, and meanwhile, the harm to the environment caused by exploitation and processing of petrochemical products can be reduced.

The invention discloses a biosensor for detecting Alzheimer's disease markers as well as a construction method and application thereof, and relates to the technical field of biosensors. The construction method comprises the following steps: after a glassy carbon electrode is cleaned, dropwise adding a RuSi NPs (at) CS compound on the surface of the glassy carbon electrode to obtain a RuSi NPs (at) CS / GCE electrode; and immersing the RuSi NPs coated CS / GCE electrode into a PHL: S double-chain solution, and carrying out an incubation reaction to obtain the biosensor. The RuSi NPs (at) CS compound is obtained by carrying out mixed reaction on ruthenium-silicon nanoparticles and chitosan; pHL: S double chains contained in the PHL: S double-chain solution are obtained by carrying out incubation reaction on carboxyl-activated PHL chains and S chains. The biosensor has the advantages of high accuracy, strong sensitivity, good selectivity and the like, and can be applied to accurate detection of the Alzheimer's disease marker A beta oligomer.

The invention discloses a siloxane-polyether copolymer modified coking defoaming agent as well as a preparation method and application thereof, and belongs to the technical field of auxiliary chemicals. The preparation method comprises the following steps: synthesizing an epoxy group functionalized siloxane oligomer, preparing a modified siloxane-polyether copolymer matrix, constructing core-shell structure functionalized silicon dioxide in situ, and carrying out blending aftertreatment, wherein DCS and SIS linkage control is adopted in the whole process. In order to overcome the defects that the compatibility of siloxane and polyether is poor, nano silicon dioxide is easy to agglomerate and the high-temperature performance attenuation is fast in the existing coking defoaming agent, a molecular bridge mediated bonding and in-situ core-shell structure construction synergistic scheme is provided, the molecular-level compatibility of components is realized, the high-temperature stability and the lasting defoaming performance of the defoaming agent are improved, and the defoaming agent has a good application prospect. The defoaming agent is suitable for delayed coking process efficient defoaming.

The invention discloses an energetic slurry toughening and photocuring 3D printing method, relates to a preparation method of energetic slurry, and aims to solve the problems that an existing energetic material is poor in mechanical property, poor in toughness and easy to crack; the particles are fast to settle in the light-cured resin, the stability is poor, and the printing precision is poor. The invention develops a photocuring high-energy resin for photopolymerization additive manufacturing. The composition contains a high-energy filler, an acrylate adhesive, whiskers and an inert plasticizer. The material has the characteristics of compatibility, printability and mechanical property, and the possibility of printing increasingly complicated high-energy articles is proved through experiments. The preparation method of the light-cured resin comprises the following steps: adding the low polymer bisphenol A epoxy acrylate and the six-functionality polyurethane acrylate; diluting monomers including 1, 6-hexanediol diacrylate and trimethylolpropane triacrylate; uniformly mixing an auxiliary agent, a thickening agent and a dispersing agent, and magnetically stirring for 30 minutes to obtain the light-cured resin. A preparation method of the energetic slurry comprises the following steps: mixing light-cured resin, whiskers, an inert plasticizer, energetic particles, a photoinitiator and a light absorber, and uniformly stirring to obtain the energetic slurry; after the energetic slurry is used for 3D printing, a sample piece is obtained, the yield reaches 95%-100%, the cost is low, preparation is easy, and the method can be applied to the field of energetic slurry 3D printing.

The invention provides an anaerobic adhesive composition, an anaerobic adhesive and a preparation method of the anaerobic adhesive. The anaerobic adhesive composition comprises a main agent and a promoting primer, and the main agent comprises the following components in parts by weight: 30-70 parts of an acrylate monomer, 5-20 parts of an acrylate oligomer, 5-20 parts of a tackifier and 1-10 parts of an amide monomer; the accelerating primer is prepared from the following components in parts by weight: 0.01 to 30 parts of phosphorus-containing acrylate monomer and 0.001 to 1 part of reaction accelerator; wherein the reaction accelerant is an organic compound containing transition metal. According to the anaerobic adhesive composition, the curing degree of the anaerobic adhesive can reach the standard in a short time (within 3 min), and high drawing strength and an excellent damage form are achieved, so that the bonding requirement of a silicon steel sheet of a motor iron core is met; and the anaerobic adhesive has the advantages of high temperature resistance, no cracking, high drawing strength, vibration resistance, good oil-resistant stability and the like.

The invention discloses a method for improving the crystallinity and catalytic water decomposition performance of a polyheptazine imino carbon nitride photocatalyst, and belongs to the technical field of photocatalytic material preparation. The preparation method comprises the following steps: firstly, by taking melamine as a precursor, carrying out thermal polymerization to obtain an oligomer melt consisting of heptazine units; then carrying out high-temperature fused salt calcination treatment in a nitrogen atmosphere to obtain carbon nitride with a certain crystallinity; and adding sodium chloride as a structure regulator, fully grinding, calcining in vacuum, washing with water, and drying to obtain the crystalline-phase carbon nitride photocatalyst with high crystallinity. The method is simple, the cost is low, the actual production requirement is met, and the synthesized photocatalyst has good polymerization degree and light absorption performance, has excellent activity of fully decomposing water to produce hydrogen and oxygen under the condition of no sacrificial agent, and has the potential of realizing photocatalytic full-decomposition water diversion and the prospect of industrial application.

The invention relates to the technical field of polyurethane, in particular to a preparation method of a two-component polyurethane pouring sealant for a filter. Comprising a component A and a component B, the component A comprises polymerized MDI and a plasticizer, and the component B comprises, by weight, 3-5 parts of castor oil, 5-20 parts of polyether polyol, 10-30 parts of an acrylate oligomer, 40-60 parts of a filler, 5-10 parts of a molecular sieve, 1-5 parts of color paste and 0.01-0.5 part of an auxiliary agent. The pouring sealant prepared by compounding the castor oil, the polyether polyol and the acrylate oligomer according to a specific ratio has excellent tensile strength, shear strength and high-temperature aging resistance.

The invention relates to the technical field of UV coatings, in particular to a waterproof wear-resistant UV coating for a floor and a preparation method of the waterproof wear-resistant UV coating. The waterproof and wear-resistant UV coating for the floor is prepared from the following raw materials in parts by mass: 30 to 60 parts of polyurethane acrylate, 20 to 40 parts of fluorinated epoxy acrylate oligomer, 20 to 40 parts of pentaerythritol tetraacrylate, 1 to 5 parts of tetraethoxysilane, 15 to 25 parts of hollow glass beads, 1 to 3 parts of ammonia water, 1 to 2 parts of trifluoropropane trimethoxysilane and 1 to 2 parts of amino-terminated polyamidoamine. The coating is prepared from 1-3 parts of graphene oxide, 1-2 parts of a photoinitiator, 1-2 parts of polytetrafluoroethylene wax, 0.5-1.5 parts of a dispersing agent, 1-2 parts of a flatting agent and 1-2 parts of a defoaming agent. The waterproof coating is excellent in waterproof effect, high in adhesive strength and excellent in dimensional stability; when the coating is subjected to mechanical actions such as friction and impact, the surface of a coated object is comprehensively protected, the wear rate is remarkably reduced, and the wear resistance is improved.

The invention discloses a hydrolysis-resistant antiskid polyurethane material as well as a preparation method and application thereof, and relates to the technical field of polyurethane materials. The hydrolysis-resistant antiskid polyurethane material comprises a component A and a component B, wherein the component A comprises polyester type acrylate polyol, aromatic isocyanate and an organic tin catalyst; the component B comprises epoxy modified polyether polyol, triethylene tetramine, a nitrogen-containing catalyst, water, a foam stabilizer, TPE particles and modified wollastonite; the component C is hydroxyl-terminated polybutadiene; the modified wollastonite is prepared by modifying wollastonite with a polyacrylate oligomer. The hydrolysis-resistant anti-slip polyurethane material provided by the invention is prepared by adopting a semi-prepolymerization method, the preparation process is easy to control, the processability is stable, and the hydrolysis-resistant anti-slip polyurethane material has excellent mechanical strength, toughness, rebound resilience, hydrolysis resistance, high and low temperature resistance, wear resistance, slip resistance, aging resistance and the like, can be used for a long time under severe conditions such as moisture or low temperature, and has a wide application prospect. And the service life of the material applied to the sole material is prolonged.

Disclosed in the present application are a 3D printing photo-curable resin and a preparation therefor. The preparation method comprises: under the constant-temperature and constant-humidity conditions of a preset temperature and a preset humidity, weighing 50-80 parts of an acrylate oligomer, 10-40 parts of a reactive diluent, 0.05-0.1 parts of an ultraviolet light absorber, and 0.01-0.05 parts of p-hydroxyanisole, adding the weighed substances into a container, and stirring the materials in the container at a first preset rotation speed; and after stirring for a first preset time, adding the weighed 5-10 parts of a cross-linking agent and 1-3 parts of a photoinitiator into the container while stirring, and stirring same for a second preset time at a second preset rotation speed under dark conditions, so as to obtain the 3D printing photo-curable resin. In this way, the resin has an extremely high strength and toughness, without a filler being added, and can avoid the problems of unstable material performance and poor printing precision.

The invention relates to a preparation method and system of high-molecular-weight polyethylene glycol oxalate, and the preparation method comprises the following steps: adding oxalic acid diester, ethylene glycol and a first catalyst, and carrying out transesterification to obtain an ester; adding a second catalyst, and carrying out a pre-polycondensation reaction on the esterified product to obtain a glycol oxalate oligomer; polymerizing the ethylene glycol oxalate oligomer, and carrying out final polymerization reaction to obtain polyethylene glycol oxalate; the molar ratio of the oxalic acid diester to the ethylene glycol is (1.05-1.3): 1. Compared with the prior art, by controlling excessive oxalic acid diester in the raw material ratio, namely controlling the molar ratio of oxalic acid diester to ethylene glycol to be greater than 1, the reaction rate of ethylene glycol is improved, self-polycondensation of ethylene glycol is prevented, further increase of molecular weight is facilitated, and meanwhile, the thermal performance of the product is improved.

The invention discloses a preparation method of polydihydroxyindole and application of the polydihydroxyindole in hair dyeing, and belongs to the field of functional materials and the field of daily cosmetics. The polydihydroxyindole is obtained in the mode that Boc-true melanin is formed after true melanin is protected through phenolic hydroxyl groups, the Boc-true melanin is subjected to oxidative degradation, separation and purification and then deprotection, the true melanin is naturally extracted melanin or chemically synthesized melanin or melanin synthesized through a microbiological method, and the oxidative degradation method is an enzymatic oxidative degradation method. The obtained polydihydroxyindole is moderate in molecular weight and has excellent permeability on hair, a strong alkaline condition is not needed in the oligomer dyeing process, and hair quality damage can be reduced; the polydihydroxyindole is oxidized again in the hair dyeing process to generate melanin, and under the condition that the pH is 5-7, and in the presence of ferric ions, the polydihydroxyindole can be more tightly combined with keratin on the hair to coat the outer layer of the hair, so that the hair color is deepened, and the effects of dyeing and protecting the hair are achieved.

The invention belongs to the technical field of green cyclic regeneration of waste bottle flakes, and relates to a method for realizing high-purity and high-yield preparation of BHET (butylated hydroxytoluene) by depolymerizing waste PET (polyethylene terephthalate), which comprises the following steps: firstly, carrying out ethylene glycol alcoholysis reaction on the waste PET bottle flakes to obtain alcoholysis liquid; the alcoholysis liquid is sequentially subjected to activated carbon decoloration, cooling crystallization (crystals in the cooled and crystallized material are in a short column shape) and solid-liquid separation to obtain a crystal mixture containing BHET, a small amount of oligomer and a small amount of ethylene glycol, then the crystal mixture containing BHET, a small amount of oligomer and a small amount of ethylene glycol is placed in a film evaporator, residual ethylene glycol is removed in a vacuum state, and the solid-liquid separation product is obtained. And finally, carrying out melt crystallization on the crystal substance containing BHET and the oligomer, and collecting a melt to obtain BHET. The purity of BHET is greater than 99%, and the yield is greater than 90%. According to the method disclosed by the invention, high-purity and high-yield preparation of BHET can be realized, the obtained BHET monomer can be directly used as a raw material for regenerating PET polyester, and a new path is provided for high-quality recovery of waste PET bottle flakes.

The invention provides a humanized monoclonal antibody for detecting a human-synuclein oligomer and application of the humanized monoclonal antibody, and belongs to the technical field of biological engineering. The light chain CDR sequence of the binding part comprises at least one of LCDR1, LCDR2 and LCDR3, and the amino acid sequence of the LCDR1 is as shown in SEQ ID NO: 1; the amino acid sequence of the LCDR2 is as shown in SEQ ID NO: 2, and the amino acid sequence of the LCDR3 is as shown in SEQ ID NO: 3. The monoclonal antibody is used as a raw material, and a unique repeated epitope double-antibody sandwich immunodetection method is adopted, so that the human a-Syn oligomer prepared in vitro or in a sample can be detected with high specificity, high sensitivity and high accuracy.

The present disclosure relates to a method that includes hydrolyzing a polyamide by contacting the polyamide with a hydrolase. In some embodiments of the present disclosure, the polyamide may include nylon-6, nylon 6,6, or a combination thereof. In some embodiments of the present disclosure, the hydrolyzing may produce aminohexanoic acid, an oligomer of aminohexanoic acid, ε-caprolactam, or combinations thereof.

The utility model provides a purification treatment device, and relates to the technical field of process water treatment. The purification treatment device comprises: a first cation exchange resin tank for adsorbing and extracting at least a part of oligomers and cations in water; a water inlet of a heating medium channel of the first heat exchanger is connected with a water outlet of the first cation exchange resin tank, and the first heat exchanger is used for cooling the entered extraction water; a water inlet of a heating medium channel of the second heat exchanger is connected with a water outlet of a heating medium channel of the first heat exchanger so as to cool the extraction water, so that the temperature of the extraction water flowing out of the heating medium channel of the second heat exchanger is lower than or equal to a first threshold value; the anion exchange resin tank is connected with a water outlet of the heating medium channel of the second heat exchanger; the second cation exchange resin tank is connected with the water outlet of the anion exchange resin tank; and the water outlet of the second cation exchange resin tank is connected with the water inlet of the refrigerant channel of the first heat exchanger. According to the invention, impurities in the extracted water can be removed.