908 results about "Nanocomposite" patented technology

The invention discloses a preparation method of a high-strength, high-hardness and ablation-resistant CuWTaTeAl gradient nano composite material. The method comprises the following steps: 1, mechanically mixing Cu80Al20 spherical coated powder, Cu90W10 spherical coated powder, WTe2 alloy powder, Ta powder and Cu powder, and then carrying out ball milling and mixing; 2, performing SPS (spark plasma sintering); thirdly, after soaking treatment, multi-pass hot rolling deformation is carried out, and then quenching treatment is carried out; and 4, annealing heat treatment. The binary spherical coating powder, the alloy powder and the elementary substance powder are subjected to ball milling and mixing to achieve uniform distribution of all elements, high-melting-point W and Ta are added to improve the ablation-resistant temperature of the composite material, large-scale copper dendrite powder is added to form gradient distribution nanocrystals, the proportion of all the elements is controlled, the lattice distortion degree is increased, and the ablation-resistant temperature of the composite material is improved. The high-strength, high-hardness and ablation-resistant CuWTaTeAl gradient nano composite material is suitable for the fields of contacts, switches, electrical connectors, resistance welding electrodes and the like.

The invention discloses a preparation method and application of a ceramic glaze layer protecting and repairing material, and belongs to the technical field of cultural relic protection. The preparation method comprises preparation of a core-shell self-repairing nanocapsule, and the preparation of the core-shell self-repairing nanocapsule comprises the following steps: reacting a calcium chloride solution with a sodium hydroxide solution, then adding sodium polyacrylate and nano ZnO, and carrying out dispersion, centrifugation, washing and other operations to prepare the nano Ca (OH) 2-ZnO composite material. The nano Ca (OH) 2-ZnO composite material of the core-shell self-repairing nanocapsule can be rapidly released through the 3.5 nm aperture of the mesoporous SiO2 shell, glaze layer cracks are physically filled and react with CO2 in air to generate CaCO3 crystals, crack plugging is achieved, meanwhile, dynamic disulfide bonds of a PU layer are broken and recombined under stress stimulation, a crack interface is repaired through chemical bonding, and the performance of the core-shell self-repairing nanocapsule is improved. The 24-hour crack repair rate is greater than or equal to 96%, and the limitation of'one-time repair 'of a traditional material is solved.

A nano composite, a nanoparticle ink composition including a solvent and the nanocomposite, and a light-emitting device including a first electrode, a second electrode facing the first electrode, and an interlayer between the first electrode and the second electrode, wherein the interlayer includes an emission layer, and at least one layer included in the interlayer is made from the nanoparticle ink composition. The nano composite includes: a metal oxide nanoparticle; and a chelating ligand bonded to a surface of the nanoparticle and including a cyclic moiety.

The invention relates to the technical field of biological separation materials, and discloses an amine-functionalized magnetic nano composite material and application thereof in protein separation and purification. The material has a core-shell structure and comprises a magnetic ferroferric oxide nano core, an ordered mesoporous silicon dioxide intermediate layer and a covalent grafted polyethyleneimine functional layer. By controlling the matching relationship between the pore diameter of mesopores and the molecular size of the polymer and adopting a crosslinking strategy, the material has high magnetic responsiveness, rapid mass transfer performance and high-density surface amino groups. The material shows high adsorption capacity, rapid adsorption kinetics and good cycle stability in the protein separation process, and is suitable for enrichment purification and metal chelating affinity separation of protein in a biological sample. According to the invention, the technical problems of low protein adsorption capacity, slow dynamics and poor cycling stability caused by compact shell layer, non-uniform amino distribution and limited mass transfer of the existing amine functionalized magnetic material are solved.

The utility model belongs to the technical field of cables, and particularly relates to a crosslinked polyethylene nano-composite power cable, which comprises a cable core, an insulating layer is arranged on the outer side of the cable core, and a buffer layer is filled between the insulating layer and the cable core; a flame-retardant layer is arranged on the outer side of the shielding layer, and a heat preservation layer is arranged on the outer side of the flame-retardant layer. By arranging the insulating layer, the shielding layer, the flame-retardant layer, the heat preservation layer, the anti-freezing layer and the wear-resistant layer, protection on the cable core can be effectively enhanced, and the cable has excellent cold resistance, good insulating performance, good flame retardance, improved wear resistance and pressure resistance when in use; therefore, the service life of the cable is prolonged.

The invention discloses marine concrete resistant to chlorine salt erosion and a preparation method thereof, and belongs to the technical field of building materials. The marine concrete is prepared from the following components in parts by mass: 280 to 350 parts of cementing material, 1100 to 1200 parts of aggregate, 150 to 180 parts of mixing water and 2.5 to 4.0 parts of high-efficiency water reducing agent, and the cementing material is prepared from 210 to 270 parts of ordinary Portland cement, 50 to 70 parts of superfine slag powder and 10 to 20 parts of modifier on the basis of the cementing material; on the basis of the modifier, the modifier is prepared from 30 to 45 parts of hexacalcium aluminoferrite, 25 to 35 parts of metaettringite, 20 to 35 parts of tobermorite, 3 to 6 parts of nano attapulgite and 2 to 4 parts of a nano composite material. The components can accelerate the early hydration of cement and the volcanic ash reaction process in the concrete hardening process, so that the concrete can form a compact microstructure in the curing period and cooperate with the curing effect of a hydration product on chloride ions, thereby remarkably improving the chloride ion penetration resistance of the concrete, prolonging the service life of the structure and improving the concrete quality. The method is suitable for port engineering, maritime work structures and buildings in salinized soil areas.

The invention discloses construction and application of a confinement enhanced photoelectrochemistry-electrochemiluminescence dual-mode biosensor, and relates to the technical field of biosensing and analytical chemistry. The preparation method of the biosensor comprises the following steps: taking a CdS (at) SiO2 (at) NaYF4: Yb / Tm nano composite material as a substrate to obtain a confinement enhanced photoelectrochemistry (PEC) and electrochemiluminescence (ECL) sensing interface; in combination with a DNA wheel nanostructure triggered by target acetamiprid, signal amplification is realized; and synchronous dual-mode quenching detection of PEC and ECL signals is realized by virtue of peroxidase-like catalytic precipitation and wide-spectrum absorption characteristics of the PtPd-CoSnO3 nanocube. The biosensor prepared by the invention has the advantages of high sensitivity, strong reliability, good selectivity and the like, can be applied to accurate detection of acetamiprid in samples such as agricultural products and the like, and has important application value in the aspects of environmental monitoring and food safety control.

A nanocomposite material including iron sulfide (FeS2) nanoparticles, iron oxide (α-Fe2O3) nanoparticles, titanium dioxide (TiO2) nanoparticles, and graphitic carbon nitride (C3N4) nanosheets and a method of its preparation. The nanocomposite is used in a method of forming oxygen gas from water using an applied voltage and photoirradiation, a method of forming hydrogen gas from water using an applied voltage and photoirradiation, and a method of photodegrading organic pollutants using visible light photoirradiation.

The invention discloses a graphene aerogel modified elastic graphite material and a preparation method thereof, and the graphene aerogel modified elastic graphite material comprises the following components by mass: 50-80 parts of crystalline flake graphite; 8 to 15 parts of graphene aerogel; 3 to 8 parts of aminated modified boron-doped carbon nanotubes; 2 to 6 parts of hydroxyapatite-cerium oxide composite nano particles; 1 to 4 parts of a polyimide-montmorillonite nano composite material; 0.5 to 3 parts of titanate coupling agent modified nano silicon dioxide; 1-3 parts of a dispersant; 2-5 parts of a binder; the amination modified boron-doped carbon nanotubes can enhance the electrical conductivity and interface bonding force of the material, the hydroxyapatite-cerium oxide composite nanoparticles improve the high-temperature stability and mechanical toughness of the material, and the polyimide-montmorillonite nanocomposite improves the corrosion resistance and resilience durability of the material. And the titanate coupling agent modified nano silicon dioxide further optimizes the dispersion uniformity of all the components, and the comprehensive performance of the material is remarkably improved.

The invention discloses a tellurium-doped copper sulfide-based nano composite material with a core-shell structure as well as a preparation method and application thereof, and belongs to the technical field of zinc ion battery negative electrode materials. The method comprises the following steps: dissolving a copper source, a sulfur source, a carbon source and a tellurium source in a mixed solution of deionized water and ethylene glycol, uniformly stirring and mixing, carrying out hydrothermal reaction and centrifugal cleaning, collecting a precipitation product, and carrying out vacuum drying; and carrying out calcination reaction to obtain the tellurium-doped copper sulfide-based nano composite material with the core-shell structure. The inner-layer microspheres are microspheres formed by stacking tellurium-doped copper sulfide flower-shaped nanosheets; and the outer coating layer is a carbon layer. Through the synergistic effect of tellurium doping and carbon coating, the electron conduction and the structural stability of the material are effectively enhanced, and the cycle performance and the rate capability of the aqueous zinc ion battery are remarkably improved. As a negative electrode of the zinc ion battery, the material can effectively improve cyclic reversibility, has remarkable reversible capacity, improves the performance of the zinc ion battery, and is suitable for industrial production and large-scale energy storage.

The invention is applicable to the technical field of catalyst preparation, and provides a nano composite material for producing H2O2 through photocatalysis and a preparation method, the nano composite material comprises titanium dioxide, nitrogen-doped carbon quantum dots and polyoxometallate, and the general formula is TiO2 / NCDx / POMy; wherein x is an integer from 1 to 4, and y is an integer from 10 to 100. According to the method, through the synergistic effect of the titanium dioxide, the nitrogen-doped carbon quantum dots and the polyacid, the self limitation and defects of the titanium dioxide in the photocatalytic H2O2 production process are effectively overcome, and the H2O2 yield is remarkably improved. Meanwhile, the composite material can still keep stable catalytic performance in a wide pH range, and a new thought is provided for solving the problem that titanium dioxide is limited by the pH environment in the process of producing H2O2 through photocatalysis.

The invention belongs to the technical field of nano composite materials, and particularly provides a corrosion-resistant flexible carbon nano polymer coating and a preparation method thereof, and the corrosion-resistant flexible carbon nano polymer coating comprises phenolic resin, bisphenol F epoxy resin, GO-NH2, self-repairing polyimide, a BYK-011 defoaming agent, talcum powder, polytetrafluoroethylene, a BYK333 flatting agent, silicon carbide, a B215 composite antioxidant, a UV531 ultraviolet light absorber and cardanol. The corrosion-resistant flexible carbon nano polymer coating prepared by the invention has excellent mechanical strength and wear resistance, good flexibility, efficient self-repairing capability and lasting corrosion resistance, the service life of the coating can be effectively prolonged, and the protection requirement in a severe environment is met.

The invention relates to an SERS (Surface Enhanced Raman Scattering) active nano composite material for detecting trace histamine in tears, SERS sensing test paper as well as a preparation method and application, and belongs to the field of biosensing and spectral analysis. At least one of the problems of low detection sensitivity, poor anti-pollution capacity, low selectivity, incapability of realizing on-site rapid and instant analysis and the like of trace histamine in tears in the prior art is solved. The SERS active nano composite material is of a core-shell structure, and comprises a noble metal nano particle core, the surface of the core is coated with the hollow zeolite imidazate skeleton-67 shell layer, namely a ZIF-67 shell layer of a hollow structure; the Raman reporter molecule is fixed on the surface of the noble metal nanoparticle core. According to the invention, the detection sensitivity, anti-pollution capability and selectivity of trace histamine in tears are improved, and non-invasive rapid detection is realized.

The invention relates to preparation and application of a desoxyribonucleic acid and desoxyribonucleic acid derivative transdermal delivery system, and belongs to the technical field of biological medicine and skin care products. Desoxyribonucleic acid and derivatives thereof have the effects of resisting aging, repairing and the like, but are difficult to penetrate through a skin barrier due to large molecular weight and strong polarity. According to the invention, hydroxyethyl chitosan, desoxyribonucleic acid and derivatives thereof are combined through electrostatic interaction to form the nano-composite. The compound is small in particle size and can promote transdermal absorption through hair follicle or cuticle gaps. The preparation method is simple, does not need an auxiliary reagent, and comprises the step of mixing a hydroxyethyl chitosan solution and a deoxyribonucleic acid derivative solution. Experiments show that the compound significantly enhances the transdermal efficiency, and has the effects of promoting cell repair and proliferation and resisting inflammation. The composition can be used for skin care products, and is high in safety and wide in application prospect.

The invention discloses a polydopamine-tea polyphenol coated copper manganese oxide composite nano-enzyme as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. According to the invention, a DA-Cu (II)-EGCG (epigallocatechin gallate) complex is formed by virtue of chelation of main components of dopamine and tea polyphenol, namely epigallocatechin gallate, and copper ions; potassium permanganate is introduced for oxidative polymerization to obtain the polydopamine-tea polyphenol / copper manganese oxide organic-inorganic hybrid nano composite material, the nano composite material is monodisperse nano particles, the average particle size is about 80 nm, the nano composite material shows excellent nano enzyme catalytic activity, active oxygen free radicals can be effectively removed, and the nano composite material can be used for preparing nano-enzyme. The material has good photo-thermal conversion performance under near-infrared light, and shows excellent photo-thermal and photodynamic synergistic antibacterial effects. The preparation method disclosed by the invention is simple, mild, environment-friendly, low in cost and convenient for batch production.

The invention discloses preparation of a GSH responsive photo-thermal chemical synergetic liquid metal nanocomposite and application of the GSH responsive photo-thermal chemical synergetic liquid metal nanocomposite in tumor treatment, and relates to the field of nano biomedical materials. According to the composite material, gallium-tin alloy (GaSn) is used as an inner core, a reduced graphene oxide (RGO) middle layer and a manganese dioxide (MnO2) outer shell are sequentially coated, a three-layer core-shell structure is formed, and the average particle size is controlled to be about 60 nm. The liquid metal composite nanomaterial has excellent photothermal conversion performance and oxidation resistance. The compound not only can be used for treating tumors and cancers, quickly killing cancer cells and effectively inhibiting tumor growth, but also can quickly deplete GSH, break dynamic balance of redox and improve ROS level in cells. Experiments show that the material shows a remarkable inhibition effect on tumor cells, has good biocompatibility and regulation and control release characteristics, and provides a new strategy for precise synergistic treatment of solid tumors.

The invention relates to the technical field of antibacterial materials, and provides a light-enzyme-heat synergistic antibacterial nano composite material and a preparation method thereof.The preparation method comprises the steps that 1, a copper-based chalcogenide with a plasma resonance effect serves as a structural template, a transition metal oxide intermediate layer and a bismuth oxyhalide epitaxial layer are sequentially constructed on the surface of the copper-based chalcogenide with the plasma resonance effect through a step-by-step continuous solvothermal method, and the copper-based chalcogenide with the plasma resonance effect serves as the structural template; forming a core-shell heterojunction with Z-type energy band matching; (2) pre-assembling a natural enzyme and a monatomic nano-enzyme in a buffer system to form a composite catalytic unit with an electron transfer channel; and (3) by taking the core-shell heterojunction as a polymerization core, under the precise temperature control condition of 0-10 DEG C, initiating active free radical polymerization through an interface, constructing a thermal response polymer shell layer on the surface of the heterojunction, and encapsulating the composite catalytic unit in a functional microdomain of a polymer network in situ. The anti-bacterial fabric can achieve a better synergistic anti-bacterial effect.

The invention belongs to the technical field of antibacterial materials, and particularly relates to a sericin / tannic acid-silver antibacterial-anti-biofilm nanocomposite as well as a preparation method and application thereof. According to the method, the TA-Ag nano material is prepared by adopting a simple water bath method; and then, dispersing SS in a TA-Ag aqueous solution to realize hydrogen bond combination of SS and TA so as to obtain the SS / TA-Ag nanocomposite with a stable structure. In the preparation process, plant polyphenol tannic acid is taken as a carrier, silver ions and tannic acid are combined by adopting a water bath method, and the antibacterial property of tannic acid is effectively improved; and the sericin is further modified through hydrogen bond crosslinking, so that the obtained composite material not only has antibacterial and anti-biofilm dual functions, but also is simple in preparation process and mild in reaction condition, and conforms to green chemistry and environment-friendly concepts.

An iron oxide-ceria nanoparticle, an iron oxide-ceria nanostructure and an iron oxide-ceria nanocomposite are provided. The iron oxide-ceria nanoparticle comprises iron oxide and ceria. The iron oxide-ceria nanostructure comprises an inorganic support and a plurality of iron oxide-ceria nanoparticles dispersed in the inorganic support. The iron oxide-ceria nanocomposite comprises: an inorganic support; a plurality of iron oxide-ceria nanoparticles dispersed in the inorganic support; and a polymer layer that encompasses the inorganic support.

This invention discloses a near-infrared long-afterglow nanocomposite, its preparation, and its application in uric acid detection, belonging to the technical field of testing or analyzing materials by measuring their chemical or physical properties. The nanocomposite comprises a near-infrared long-afterglow luminescent center and an outer layer of organosilicon-doped mesoporous silicon containing tetrasulfide bonds. Under near-infrared light excitation, this nanocomposite exhibits excellent afterglow luminescence enhancement response to hydrogen peroxide. Since the product of uric acid decomposition by uricase is hydrogen peroxide, this composite enables highly sensitive and rapid detection of uric acid in blood. The composite provided by this invention has uniform particle size and high stability, effectively eliminating autofluorescence interference from biological components and improving detection accuracy.

The invention belongs to the technical field of super capacitors, and particularly relates to a super capacitor electrode material and a preparation method thereof. Zinc selenide is tightly compounded on an MXene material to obtain the nano composite material, and the zinc selenide is obtained through in-situ conversion of a ZIF-7 precursor. The material realizes a point-line-surface three-dimensional conductive network in which ZnSe nanoparticles, in-situ derived carbon and MXene nanosheets are tightly coupled, has a high-defect carbon structure and an excellent electron conduction path, realizes ultrahigh specific capacitance, excellent rate capability and excellent long cycle stability, and greatly improves comprehensive electrochemical performance.

The application discloses a kind of multi-element ultra-high temperature nanocomposite ceramic matrix composites and preparation method thereof, the multi-element ultra-high temperature nanocomposite ceramic matrix composites are composed of multi-element ultra-high temperature nanocomposite ceramic and porous fiber body, wherein multi-element ultra-high temperature nanocomposite ceramic is composed of oxygen-free silicon-based ceramic and multi-element transition metal carbonitride uniformly distributed therein, and the preparation method is: at least two metal element complexes are reacted with silicon-based polymer to obtain single-source precursor polymer;Then porous fiber body is placed in single-source precursor polymer solution for multiple times of impregnation pyrolysis, and the composite material provided by the application has a nanocomposite structure, an ultra-high temperature ceramic multi-element single-phase solid solution, the type, content and ratio of metal elements can be adjusted, the ultra-high temperature ceramic in the matrix is uniformly distributed and has a nanoscale grain size, and the method can avoid damage to the fiber during preparation, thereby achieving simultaneous improvement of the mechanical properties and oxidation ablation resistance of the composite material.

The invention provides a water-based ultraviolet curing coating with an antistatic function and a preparation method thereof, and the water-based ultraviolet curing coating comprises the following components in parts by weight: 100-200 parts of water-based polyurethane acrylate, 2-5 parts of a photoinitiator, 10-20 parts of a filler, 0.5-3 parts of an auxiliary agent, 10-20 parts of a nano antistatic agent and 20-50 parts of deionized water. Wherein the water-based polyurethane acrylate is polyether type water-based polyurethane acrylate, polyester type water-based polyurethane acrylate or a composition of any one or two or more than two of polyether type water-based polyurethane acrylate and polyester type water-based polyurethane acrylate. The innovation points of the invention are as follows: a polyaniline-graphene nanocomposite with a nanosheet microstructure is developed by taking a graphene nanosheet as a polymerization template, and short-fiber polyaniline is developed as a novel antistatic agent by taking a carbon nanotube as a material morphology and interface action regulator; the anti-static performance of the anti-static coating is greatly improved, an organic solvent does not need to be added, and the anti-static coating is environmentally friendly and also has good adhesive force, flexibility, water resistance and chemical stability.

The invention discloses an ordered ion channel polyamide nano composite membrane, a preparation method and application, relates to the field of lithium magnesium membrane separation, and aims to solve the problem of poor selectivity in the prior art. The technical scheme is as follows: amino benzo crown ether is covalently grafted on an ultrafiltration base membrane in situ through diazotization-coupling reaction; then, a polyamide compact layer is prepared on the crown ether nano layer subjected to in-situ self-assembly through interfacial polymerization, and the polyamide nano composite membrane with the ordered ion transmission channel is jointly constructed. The residual amino groups on the surface of the in-situ covalent grafted crown ether nano layer can also participate in interfacial polymerization reaction, so that the ordered ion channel crown ether macromolecular layer and the polyamide compact layer are connected through chemical bonds to jointly form the polyamide nano composite membrane with the ordered ion transmission channel. And the method is suitable for extracting lithium from the salt lake brine.

This invention discloses a SiC-supported LDH nanocomposite material, its preparation method, and its application as a microwave absorbing and corrosion-resistant material. The SiC-supported LDH nanocomposite material has a core-shell structure, wherein the core is silicon carbide nanowires and the shell is a layered bimetallic hydroxide doped with a third metal. nw The loading of the third metal-doped layered bimetallic hydroxide is 43.1%–168%. This invention improves the microwave absorption performance of the composite material by adjusting the LDH shell content and doping the LDH with cobalt to form a ternary LDH. Furthermore, the core-shell structure of the SiC-loaded LDH nanocomposite not only provides multiple scattering conditions for microwaves but also acts as a physical barrier, extending the corrosion path and acting as a labyrinth effect to hinder the intrusion of corrosive media. Moreover, the LDH memory effect and anion exchange effect further resist chloride ion intrusion, achieving a lightweight, integrated application of microwave absorption and corrosion protection.

The present invention provides a visual indicator film for the freshness of fresh-cut fruits, a preparation method, the use and a detection method. The preparation method comprises the following steps: preparing a Co-based MOF; washing and activating the Co-MOF; preparing a CMC-Na-based thin film; and preparing a CMC-Na-based thin film, and thereby obtaining an indicator film for phenol red (PR) or an indicator film for bromothymol blue (BTB). In the present invention, an irregular spherical Co-based metal organic framework (Co-MOF) loaded with PR or BTB is prepared, and the nanocomposites Co-MOF / PR and Co-MOF / BTB are obtained after dyes and the MOF are adsorbed by means of the hydrogen bond interaction. Then, the nanocomposites are embedded into a sodium carboxymethyl cellulose (CMC-Na) base material to prepare CO2-responsive packaging materials, namely, a CMC-Na / PR / Co-MOF and a CMC-Na / BTB / Co-MOF, which are used for monitoring the freshness of fruits in real time and in situ. The Co-MOF-based composite thin film has good water resistance, time-temperature stability and mechanical properties, and also exhibits enhanced ultraviolet-visible light barrier properties, dye migration resistance and thermal stability. The visual indicator film for the freshness of fresh-cut fruits can effectively reflect the concentration of CO2, and is suitable for real-time and in-situ monitoring of the freshness of fruits.

The invention relates to the field of floors, and particularly discloses a floor with a self-cleaning function and a preparation method.The floor comprises a main body layer, the top face of the main body layer is sequentially provided with a self-cleaning coating, an anti-fouling protection layer, a repairing function layer and a surface layer, and the self-cleaning coating is a nano composite coating; the anti-fouling protection layer is a polyurethane resin and super-hydrophobic substance mixed coating, the repairing function layer is a polyurethane resin and microcapsule mixed coating, repairing components are contained in microcapsules, the surface layer is a mixed coating of polyester resin, wear-resistant particles and an anti-ultraviolet additive, and the surface layer is a polyurethane resin and super-hydrophobic substance mixed coating. The floor with the self-cleaning function has the super-hydrophobic function, the self-cleaning function, the antifouling function, the wear-resisting function and the self-repairing function, and the high-performance requirement for the floor in the modern home and commercial environment is met.

This disclosure provides an optically active nanocomposite material having a textured substrate and a multilayer optical stack comprising multiple nanosheets. The nanosheets may be chiral and composed of materials such as transition metal chalcogenides, MXenes, or nanocarbon. The optically active nanocomposite material exhibits linear birefringence (LB) and linear dichroism (LD), and optionally circular dichroism (CD). The nanocomposite material also exhibits optical asymmetry. g The factor may be greater than or equal to 1. Furthermore, the nanocomposite material exhibits thermal stability, for example, remaining stable at temperatures above or equal to about 250 °C. This disclosure also provides different methods for preparing such nanocomposite materials using a layer-by-layer self-assembly (LBL) process.

The present invention belongs to the field of biomedicine. Provided are an organic molecular self-assembly serving as a carrier-free system, and a preparation method therefor and the use thereof. Provided is a self-assembly, which is composed of steroidal molecules, and by means of optimizing the molecular structures of these steroids and critical aggregation concentrations thereof, a carrier-free system formed via self-assembly of the steroidal molecules is prepared. The carrier-free system can be loaded with a drug to prepare a drug nanocomposite. In the nanocomposite, the efficacy of the drug is improved, and the effects of reducing toxicity and improving efficacy can be achieved. If the steroid molecules used are themselves biologically active, the pharmacological activity of the steroid molecules remains unaffected after being prepared into the drug nanocomposite. The carrier-free system has the advantages of both a carrier-free nano-preparation and a nano-preparation using a conventional material as a carrier.

The application relates to a sensor for synchronously detecting enniatin and roquefortine based on a double-potential electrochemiluminescence immunoassay technology as well as a preparation method and a detection method thereof. The sensor comprises a base electrode, a sensing interface composed of a nanocomposite is modified on the surface of the base electrode, mixed coated antigens including ENNs-BSA and AOH-BSA fixed on the sensing interface, mixed probes including a cathode probe and an anode probe, the cathode probe is Zr-Por-MOF-ENNs Ab which is obtained by marking ENNs antibodies with a porphyrin zirconium metal organic framework, the anode probe is Ce-In-MOF@ABEI-AOH Ab which is obtained by marking AOH antibodies with ABEI loaded on a cerium-doped indium metal organic framework, and a detection solution containing a single co-reactant potassium persulfate. The application can realize one-time sample adding, double-potential scanning and synchronous quantification for two kinds of mycotoxins of enniatin and roquefortine.