The invention discloses a bio-responsive
high polymer material and application thereof, and belongs to the technical field of biomedical materials. The bio-responsive high-molecular material provided by the invention contains polymers shown as formulas i to viii. Wherein the polymers of the formulas i to viii have excellent
fluorescence performance, aggregation-induced
fluorescence enhancement performance, multicolor
luminescence performance and biological response capability based on a
redox reversible switch, and can be applied to sensing, counterfeiting prevention,
metal ion detection, multicolor imaging of in-vivo and in-vitro cells and / or tissues and quantitative detection of in-vivo and in-vitro oxidized and / or
reducing substances;
active oxygen in in-vivo and in-vitro tissues and cells can be removed to achieve long-acting anti-inflammatory and anti-oxidation effects, and the compound can be used for treatment of
oxidative stress related diseases and
visual monitoring of the treatment process; the
biological activity of enhancing tissue retention, stimulating collagen generation, repairing tissue and resisting oxidation and aging of the tissue is achieved, and the effect of filling and repairing in-vivo cells and tissue can be effectively improved; the compound also has the capability of being chelated with
metal ions to form a high-molecular
metal complex, and can be used for resisting tumors, resisting
bacteria, filling and
repairing tissues, promoting collagen generation and the like.