12772 results about "Gelatin" patented technology

The invention is directed toward an osteoimplant for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing composition of demineralized allograft bone material mixed with an aqueous phosphate buffered gelatin which when lyophilized to remove water from the composition cross links the gelatin to form a solid structure.

The present invention aims to provide a seamless capsule free of an interfacial tension modifier and a gelling agent. The present invention provides a shell formed by a shell composition containing gelatin and a plasticizer, but free of an interfacial tension modifier and a gelling agent, and a seamless capsule comprising a capsule content free of an interfacial tension modifier and a gelling agent.

Non-woven fibrous scaffolds made by electrospinning from the synthetic biodegradable polymer such as, for example, poly(lactic-co-glycolic acid) (PLGA) and natural proteins, such as, for example, gelatin (denatured collagen) and elastin and a method of making thereof.

PCT No. PCT/JP97/04203 Sec. 371 Date May 20, 1999 Sec. 102(e) Date May 20, 1999 PCT Filed Nov. 19, 1997 PCT Pub. No. WO98/22155 PCT Pub. Date May 28, 1998The present invention offers an artificial tube for nerve which can remain in the body until the nerve regenerates while does not remain as a foreign body in the body following nerve regeneration, and which induces axons regenerated from severed nerve stumps, can promote infiltration of blood capillaries from the body and regeneration of nerve tissue. The present invention comprises a tube 10 or 20 having coating layers 12, 13 or 22, 23 composed of gelatin or collagen on the inner and outer surfaces of a tube 11 or 21 composed of a material being biodegradable and absorbable in vivo, and a collagen body 30 or 40 having cavities 32, 33 or 41 which pass through said tube so as to be substantially parallel to the axis of said tube; wherein, said cavities are filled with a matrix gel.

A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided tissue regeneration. The membrane is composed of at least one non-woven fabric layer made of collagen fibers, or a laminated membranous substance consisting of at least one non-woven fabric layer made of collagen fibers and at least one sponge layer made of collagen, and a coating layer of gelatin or hyaluronic acid on the surface or surfaces of the above membrane. Preferably, the membrane comprises one to six compressed cross-linked collagen non-woven fabric layers wherein a layer has a fibers having a fiber diameter of 0.05 mm to 1.0 mm, a bulk density of 5.0×10⁻⁴ to 5 g/cm³ and a thickness of 0.1 mm to 50 mm, and a coating layer containing gelatin or hyaluronic acid and having a thickness of 0.05 mm to 20 mm, wherein the coating layer covers one or both sides or a part or whole of the surface of the membrane.

The invention provides nutrition noodles containing Chinese medicine components and a preparation method thereof; the nutrition noodles are prepared from the raw materials which comprise flour and the following Chinese medicine components, wherein every 5kg of flour is mixed with the Chinese medicine components by weight: 4 to 10g of ginseng, 3 to 6g of radix codonopsitis, 3 to 6g of astragalus, 4 to 8g of polygonatum, 2 to 5g of atractylode, 10 to 20g of yam, 3 to 6g of rehmannia, 4 to 8g of polygonum, 3 to 8g of angelica, 4 to 10g of donkey-hide gelatin, 5 to 10g of medlar, 4 to 6g of root of herbaceous peony, 4 to 8g of radix, 3 to 6g of asparagine, 4 to 8g of polygonatum, 4 to 8g of root of straight ladybell, 10 to 15g of lily, 4 to 8g of ligustrum lucidum, 5 to 8g of psoralen, 4 to 8g of cistanche, 3 to 8g of morinda, 4 to 7g of dodder, 5 to 10g of cornus, 3 to 7g of schisandra, 3 to 7g of poria, 5 to 8g of coix seed, 3 to 6g of clove, 4 to 8g of nutmeg, 3 to 6g of fructus tsaoko, 4 to 8g of rhizoma gastrodiae, 4 to 8g of kidney tonifying nut, 3 to 6g of fructus momordicae, 10 to 20g of lotus seeds and 3 to 7g of notoginseng. The nutrition noodles have various health care effects.

A method for preserving blood platelets is described. The method uses 1%-3% gelatin in the platelet preservation medium, and storing the platelets in the preservation medium at temperatures below 0° C. and at least 70 atmospheres pressure for at least one day.

A composition for delivering a tumor therapeutic agent to a patient includes a fast-release formulation of a tumor apoptosis inducing agent, a slow-release formulation of a tumor therapeutic agent, and a pharmaceutically acceptable carrier. An apoptosis-inducing agent in a pharmaceutically acceptable carrier may be administered before or concomitantly therewith. Nanoparticles or microparticles (e.g., cross-linked gelatin) of the therapeutic agent (e.g., paclitaxel) also may be used. The nanoparticles or microparticles may be coated with a bioadhesive coating. Microspheres that agglomerate to block the entrance of the lymphatic ducts of the bladder to retard clearance of the microparticles through the lymphatic system also may be employed. This invention also uses drug-loaded gelatin and poly(lactide-co-glycolide) (PLGA) nanoparticles and microparticles to target drug delivery to tumors in the peritoneal cavity, bladder tissues, and kidneys.

The invention discloses green tonic lucid ganoderma (three immortals) cream for preventing sub-health and a preparation method thereof. Lucid ganoderma is used as a main raw material. The preparation method comprises the following steps of: scientifically blending the lucid ganoderma and other Chinese medicinal materials, soaking, decocting and concentrating the materials, then properly adding nutrient or dietary supplements into the concentrate, and finally adding refined honey (or honey) or colloid medicament such as previously melted donkey-hide gelatin and the like serving as a cream collecting agent into the mixture to form the green tonic lucid ganoderma (three immortals) cream. The green tonic lucid ganoderma (three immortals) cream has the effects of nourishing and building the body, prolonging the life, preventing and treating diseases, effectively preventing sub-health and the like, and has unique health promotion significance for promoting the three aspects of 'essence, energy, spirit' of the human body in particular.

The invention is a fibrin glue that avoids the use of fibrinogen and thus eliminates the need for premixing and premature clot formation. The fibrin glue of the invention comprises thrombin, thromboplastin and calcium and may have clotting Factors, VII, IX and X, and the like. The invention also comprises a biosealant for use with the fibrin glue without fibrinogen or for use alone. The biosealant is a two component mixture of gelatin/resorcinol and glyoxal/glutaraldehyde/4-(p-maleimidophenyl) butyric acid. The two components are mixed on use.

A cartridge for an e-vaping device includes an ethanol-free gel formulation. The ethanol-free gel formulation includes a vapor former, water, and a biopolymer. The biopolymer may be included in an amount ranging from about 0.01% by weight based on the weight of the ethanol-free gel formulation to about 2.0% by weight based on the weight of the ethanol-free gel formulation. The biopolymer may be one or more of agar, kappa carrageenan, gelatin, sodium alginate, gellan gum, pectin, and combinations thereof. The cartridge also includes a heater configured to heat liquid from the gel formulation to a temperature sufficient to release a liquid/semi-liquid component from the gel, which component thereupon forms a vapor.

The present disclosed subject matter relates to methods and compositions for restoring a diseased or damaged tooth such that infection is inhibited or eliminated and pulp regeneration is facilitated. The disclosed subject matter also includes a composition comprising a physiologically acceptable matrix seeded with pulp cells. The matrix can be capable of being injected into the pulp chamber of a tooth. In some embodiments, the matrix of a composition includes a hydrogel (e.g., collagen, chitosan, alginate, MATRIGEL™, gelatin, JELL-O®, fibrin), a mesh (e.g., polylactide-coglycolide (PLGA) mesh, polylactide (PLA) mesh, or polyglycolide (PGA) mesh, a cross-linked fiber mesh, a nanofiber mesh, a mesh fabric, biodegradable polymer mesh), a microsphere (biodegradable polymer microsphere, a hydrogel microsphere), or a combination of any of the foregoing. In yet other embodiments, the matrix includes a nanofiber, an artificial three-dimensional scaffold material, or a synthetic three-dimensional scaffold material.

The invention provides a class of samples that model the human body. This family of samples is based upon emulsions of oil in water with lecithin acting as the emulsifier. These solutions that have varying particle sizes may be spiked with basis set components (albumin, urea and glucose) to simulate skin tissues further. The family of samples is such that other organic compounds such as collagen, elastin, globulin and bilirubin may be added, as can salts such as Na+, K+ and Cl-. Layers of varying thickness with known index of refraction and particle size distributions may be generated using simple crosslinking reagents, such as collagen (gelatin). The resulting samples are flexible in each analyte's concentration and match the skin layers of the body in terms of the samples reduced scattering and absorption coefficients, mums and muma. This family of samples is provided for use in the medical field where lasers and spectroscopy based analyzers are used in treatment of the body. In particular, knowledge may be gained on net analyte signal, photon depth of penetration, photon radial diffusion, photon interaction between tissue layers, photon density (all as a function of frequency) and on instrument parameter specifications such as resolution and required dynamic range (A/D bits required). In particular, applications to delineate such parameters have been developed for the application of noninvasive glucose determination in the near-IR region from 700 to 2500 nm with an emphasis on the region 1000 to 2500 nm (10,000 to 4,000 cm-1).

Disclosed is a biocompatible, hemostatic, cross-linked gelatin composition comprising a biocompatible material comprising cross-linked gelatin and a sufficient amount of wetting agent to permit uniform wetting of the sponge in the presence of an aqueous solution.

A crystallizable, purified chondroitinase ABC having a molecular weight of about 100,000 dalton by the measurement of the SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and the measurement by the gel permeation chromatography method, having alanine as the N-terminal amino acid and proline as the C-terminal amino acid. A process for the purification of the crystallizable purified chondroitinase ABC comprising removing nucleic acid from an surfactant solution extract obtained from cells of chondroitinase ABC-producing microorganisms and chromatographically treating by concentration gradient elution using a weak cation exchange resin or a strong cation exchange resin. A composition comprising a chondroitinase and serum albumin, gelatin, or a nonionic surfactant.

The invention generally provides compositions and methods for promoting and enhancing wound closure and healing. Specifically, the invention provides a biologic composition which comprises a support layer which serves as transport scaffold, for example made of gelatin, which is coated or impregnated with a bio-adhesive molecule such as rose bengal or glyceraldehyde. The composition can also comprise an artificial or biological matrix, optionally processed (i.e. cleaned and coated with extracellular matrix proteins) to enhance cell attachment and survival. The composition can further comprise a monolayer of epithelial, endothelial cells or mesenchymal cells. The invention provides methods for using the compositions for treating wounds due to disease, trauma or surgery. Specific methods for treating ocular wounds are provided.

The present disclosure describes a delivery device for administration of nutraceuticals or pharmaceuticals, which device contains a soft gel shell comprising a gelatin-based water soluble film forming polymer, an acid insoluble polymer, and at least one reducing sugar and water, including processes, gel mixtures used for device production, and coatings containing such gel mixtures.

The invention discloses a blumea oil microcapsule textile composite finishing agent and use thereof. Gelatin or acacia of natural polymers is used the main ingredient of a wall material, the blumea oil serving as a Chinese medicinal material is used as a core material, and complex coacervation is adopted to prepare an blumea oil microcapsule aqueous emulsion; a shrink-resistance crosslinker and a catalyst are added to be combined with the blumea oil microcapsule aqueous emulsion into a multifunctional blumea oil microcapsule textile composite finishing agent; researches on the use of blumea oil microcapsules in textile finishing are carried out; and a novel cross linked graft method is used to perform the microcapsule finishing of textiles to form chemical bonds between the microcapsules and the textiles though the shrink-resistance crosslinker and free formaldehyde molecules in 2D resin further participate in a cross-linking and curing reaction as a microcapsule curing agent, so the textiles achieve a long lasting antibacterial and health-care function, a shrink-resistance function and low formaldehyde release content performance.

Ceramic materials operable to repair a defect in bone of a human or animal subject comprising a porous ceramic scaffold having a bioresorbable coating, and a carrier comprising denatured demineralized bone. The ceramic may contain a material selected from the group consisting of hydroxyapatite, tricalcium phosphate, calcium phosphates, calcium carbonates, calcium sulfates, and combinations thereof. The compositions may also contain a bone material selected from the group consisting of: bone powder, bone chips, bone shavings, and combinations thereof. The bioresorbable coating may be, for example, demineralized bone matrix, gelatin, collagen, hyaluronic acid, chitosan, polyglycolic acid, polylactic acid, polypropylenefumarate, polyethylene glycol, or mixtures thereof.

A wound dressing is provided comprising a wound treatment composition (1) including at least one absorbent or adsorbent compound contained within a sheath having an operatively inner and an operatively outer wall (5, and 6 respectively). The wound dressing is characterized in that the surface of the operatively inner wall that is to contact a wound in use is a substantially smooth continuous surface, conveniently of a plastic inner wall, selected for easy release from a wound. The inner wall is perforated (7) to enable exudate or slough to pass therethrough. The invention also provides a wound treatment composition characterized in that it comprises, in combination, an adsorbent material, preferably silica, for adsorbing moisture on or around a wound; and, a collagen, conveniently gelatin.