316results about How to "Easy to synthesize" patented technology

A method of detecting the presence of an ion includes contacting a nucleic acid enzyme with a sample suspected of containing the ion, where the enzyme contains a ribonucleotide and is dependent on the ion to produce a product from a substrate, and measuring an amount of the product produced. The ion is Pb<2+>, and is in the presence of other ions.

A zinc complex represented by formula (I-0):

{wherein R may be the same or different from each other and represents H; an alkyl group having 1 to 16 carbon atoms; an acyl group, a carboxyalkyl group, an acylalkyl group, a carbamoylalkyl group, a cyanoalkyl group, a hydroxyalkyl group, an aminoalkyl group or a haloalkyl group (here, a carbon number at an alkyl portion of these groups is 1 to 16); a carboxyl group; a carbamoyl group; a hydroxyl group; a cyano group; an amino group or; a halogeno group (provided that all are Hs are excluded)} which is capable of capturing a substance having an anionic substituent.

The invention discloses epoxy organosilicone ultraviolet curing coating modified by (methyl) acrylic acid and a preparation method thereof. The coating comprises epoxy organosilicone modified by (methyl) acrylic acid, an epoxy (methyl) acrylate resin, active diluent, a photoinitiator, an epoxy hardener and an auxiliary agent. The coating not only has the advantages of the epoxy organosilicone modified by (methyl) acrylic acid, has high toughness, weather resistance and water resistance, but also needs no organic solvents in the process of preparing the coating and enjoys simple required curingconditions.

The invention relates to a release-controllable antibiotic hydrogel and a preparation method and application thereof. The release-controllable antibiotic hydrogel based on aminoglycoside antibiotics is formed by crosslinking the oxidized polysaccharide macromolecules and the aminoglycoside antibiotics through acid-sensitive schiff base groups; the schiff base bonds are broken under the acid environment produced by bacteria infection, so that the gel is degraded, and the antibiotics is released according to requirements. The invention also provides antibacterial application of the oxidized polysaccharide-aminoglycoside antibiotics hydrogel in vitro and in vivo. The release-controllable antibiotic hydrogel has the advantages that the preparation is simple, and the cost is low; the strength, shape and degrading of the gel, the medicine release rate and the like can be controlled according to the content of antibiotics, the broad-spectrum high-efficiency antibacterial property is realized, and the antibacterial effect is better than the antibacterial effect of multiple types of commercial antibacterial gels on market; the hydrogel may be prepared into creams, implants and medical apparatus coatings, so as to resist the infection by gram-negative bacterium, gram-positive bacterium and the like.

The present invention is inverse emulsion process of preparing amphoteric polymer, and belongs to the field of water soluble polymer synthesizing technology. Amphoteric monomers DMPS and AM are polymerized in reverse emulsion with ternary composite oxidation-reduction initiating system comprising KPS, TMEDA and DMAEMA at normal temperature to obtain high molecular weight amphoteric water soluble polymer. The polymer has high water solubility, obvious í‹reverse electrolyte effectíŒ and good heat resistance and salt tolerance. Its emulsion may be used in oil field production, waste water treatment and other fields, and it may be further prepared into powdered product with wide application in medicine, daily chemical, water treatment, papermaking, oil field production and other fields.

The invention discloses application of a CMKLR1 micromolecule antagonist to control nonalcoholic fatty liver and hepatitis. The application of the CMKLR1 micromolecule antagonist to control nonalcoholic fatty liver and hepatitis is proved according to the following steps: employing alpha-NETA with different concentration to intervene a nonalcoholic fatty liver in-vitro model, and performing result detection; and employing alpha-NETA with a quantitative concentration to intervene a nonalcoholic fatty liver in-vivo model, detecting acquired tissue. The CMKLR1 micromolecule antagonist is capable of specifically antagonizing GPCR receptor ChemR23, and provides a new tool for medicines treating nonalcoholic fatty liver or fatty liver hepatitis. The CMKLR1 micromolecule antagonist is relatively simple in synthesis and relatively low in cost, and has extremely good market application prospect on control of nonalcoholic fatty liver and hepatitis.

The invention provides a method for synthesizing silver nanoclusters by the aid of single-stranded DNA (deoxyribonucleic acid) used as a template, and belongs to the technical field of nano materials. By the method, problems of complicated production and excessively high cost of nano-silver for detecting mercury ions at present are solved. The method for synthesizing the silver nanoclusters by the aid of the single-stranded DNA used as the template is characterized in that the single-stranded DNA containing cytosine and guanine is used as the template and is mixed with Ag<+> solution to obtain a mixture, reducing agents are added into the mixture, and the fluorescent silver nanoclusters can be acquired after reduction reaction is performed on the mixture with the reducing agents. The method has the advantages that polyinosinic acid (PI) and polycytidylic acid (PC) which are commercially available are used as the template in the simple, low-cost, environment-friendly and reliable method for synthesizing the silver nanoclusters; fluorescence is utilized, and fluorescent silver nanocrystals are synthesized from the polyinosinic acid, the polycytidylic acid and the like without special design or preprocessing; and the novel silver nanoclusters are excellent in selectivity and sensitivity, can be applied to detecting Hg<2+>, and are feasible and have a future development prospect in the aspect of monitoring pollutants in water.

The invention, which belongs to the technical field of agriculture, particularly relates to a polypeptide organic liquid fertilizer for increasing the yield of latex and relieving tapping panel dryness, which is prepared with polypeptide, glucose, monopotassium phosphate, zinc sulfate, ammonium molybdate, magnesium sulfate, calcium nitrate, boric acid and water. Combined with the characteristic and rule that rubber trees can absorb and utilize nutrient, the invention utilizes the chemical bonding effect of the free carboxyl group and amino group of the polypeptide on cations and anions to promote the nutrient absorption of latex, photosynthesis and the synthesis of rubber latex, enhance the regeneration capability of bark cambium and reduce the occurrence of tapping panel dryness, thus effectively increasing the yield of latex and relieving the occurring degree of tapping panel dryness.

The invention relates to a method for preparing a mordenite molecular sieve. The method comprises the following steps of: dissolving an aluminum source in a sodium hydroxide solution, adding silicon sources, stirring at room temperature by strong magnetic force, and dispersing for a period of time; mixing the silicon sources which are dispersed uniformly and an aluminum source solution to form glue, adding a zeolite molecular sieve containing a five-membered ring as a crystal seed, stirring and mixing uniformly by the strong magnetic force at room temperature, and transferring the mixture into a reaction crystallization kettle, and performing crystallization reaction at the temperature of between 150 and 170 DEG C for 0.5 to 3 days; and performing suction filtration, washing and drying conventionally to obtain the mordenite molecular sieve. According to the method, an expensive organic amine template agent is not used as a structure guiding agent, and the zeolite molecular sieve which is wide in using, low in cost and readily available and contains the five-membered ring is used as the crystal seed to synthesize the mordenite molecular sieve with a high silica-alumina ratio directly, so the prepared mordenite molecular sieve has the advantages of high crystallinity and purity, controllable granular sizes and appearance, high yield, convenience for industrial production and the like.

[Problem]

To provide a 2′-modified ribonucleoside or the like which has a high duplex-forming ability.

[Solution]

The present invention is generally based on the finding in embodiments that a modified form of a ribonucleoside or the like having an alkoxymethyl protective group can be imparted with a high duplex-forming ability by introducing, as a substituent, a halogen atom into the protective group moiety. As explained before, a modified form of RNA having an alkoxymethyl protective group has a low duplex-forming ability. A modified form of RNA having a halogen-substituted alkoxymethyl protective group, however, exhibits a high duplex-forming ability that is comparable to the duplex-forming ability of a 2′-O-methyl modified nucleic acid.

A preparation method of a ternary anode material of a lithium ion battery comprises the steps of: 1) uniformly mixing nickel salt, cobalt salt, manganese salt, and a lithium compound at a stoichiometric ratio of (2-6):(2-3):(2-4):1, 2) grinding for 2-8h by taking alcohol as a grinding medium, 3) drying a mixture ground in Step 2) at 100-120 DEG C, obtaining reaction powder, 4) applying plasma electric arc on the reaction powder to fuse the reaction powder, and 5) injecting the fusion reaction powder into a cooling device with oxidizing gas, and forming a spherical fine particle through oxidation and cooling. With the adoption of the preparation method of the ternary material, the ternary anode material can be synthesized quickly and conveniently, is regular in morphology, is highly spherical, and has stable electrochemical performances, high purity and uniform components. According to the method, the ternary anode material with the uniform components and stable performances can be quickly synthesized through plasma high-temperature fusion of ingredients.

Provided is an ionic liquid compound with anion containing double Lewis base functional groups. A cation of the ionic liquid compound with the anion containing the double Lewis base functional groups is tetra-alkyl quaternary ammonium, tetra-alkyl quaternary phosphine or N, N-dialkyl-imidazole. The anion is an organic anion which simultaneously contains a carboxylate radical perssad with weak Lewis basicity and a tertiary amine perssad (trialkylamine or tertiary amine on a heterocycle) with the weak Lewis basicity. The ionic liquid compound with the anion containing the double Lewis base functional groups is used for selectively removing hydrogen sulfide (H2S). When partial pressure of the H2S is respectively 10kPa, 20kPa, 50kPa and 100kPa, a molar ratio between an absorptive amount of the H2S and the ionic liquid compound with the anion containing the double Lewis base functional groups is respectively 0.409, 0.484, 0.638 and 0.809. When the partial pressure of the H2S is respectively 10kPa, 20kPa, 50kPa and 100kPa, ideal absorption selectivity of the ionic liquid compound with the anion containing the double Lewis base functional groups to H2S/carbon dioxide (CO2) is respectively 60.3, 39.1, 21.8 and 15.8. The invention discloses a preparation method of the ionic liquid compound with the anion containing the double Lewis base functional groups.

The invention provides an anticancer intermediate based on PKI-587 and a polyethylene glycol coupled anticancer drug, and preparation methods and application thereof, belonging to the field of treatment of cancers. The anticancer intermediate has a general structural formula as described in the specification, and at least one AC in the general structural formula is the anticancer drug PKI-587. Thepolyethylene glycol coupled anticancer drug has a general structural formula as described in the specification. The above two drugs can realize combined medication of the targeting anticancer drug PKI-587 and a plurality of other anticancer drugs, so toxic response caused by mutual influence and pharmacokinetics of a plurality of other anticancer drugs can be prevented during individual administration of the anticancer drugs, multidrug resistance of cancers is overcome, and synergistic effect is exerted; and the two drugs can be used for preparing anticancer drugs with targeting effect and have critical clinical value and wide market prospects.

The invention relates to a preparation method of Zn-ZSM-5 and an application of Zn-ZSM-5 in preparing propylene via propane dehydrogenation. A Pt based catalyst is widely applied to prepare propylene via the propane dehydrogenation, but the catalyst causes severe carbon deposition under a high temperature condition, and is poor in stability and high in production cost. In order to solve the above technical problems, the invention provides a method of crystallizing and synthesizing a Zn-ZSM-5 catalyst by obtaining a molecular sieve precursor by an aerosol assistance method and taking tetrapropylammonium hydroxide as a template. The invention further provides a new application of the Zn-ZSM-5 catalyst in preparing propylene via the propane dehydrogenation. The catalyst has a simple synthesis process, the dosage of the template is low, the pollution is small, the productivity and a single-kettle utilization rate are high, the energy consumption and cost are low, and synthesized Zn-ZSM-5 has a relatively high propane conversion rate, propylene selectivity and reaction stability and has obvious social and economic benefits.

The invention discloses a method for producing catharanthus roseus alkaloid. The method comprises the following steps: firstly, dedifferentiation culture is performed on the explant of the catharanthus roseus to get the callus of the catharanthus roseus, and through succesive transfer culture, loose and quick-growing cell line is obtained; secondly, the cell line of the callus of the catharanthus roseus obtained in the step one is processed through inducing the culture in basal culture medium provided with colchicines to get polyploidy cell line, and then expanding culture is performed to get a large amount of catharanthus roseus polyploidy cells; thirdly, the catharanthus roseus polyploidy cells are inoculated into a deffined medium to get cells being rich ofcatharanthus roseus secondary metabolites. The method of the invention produces the catharanthine with the catharanthus roseus, the industrial production of the catharanthine can be firmly realized, the production cost is low, the culture period is short, the production is not influenced by natural environment and climate, and the year-round production can be realized.

The invention discloses application of a trisilazane-rare earth complex in catalysis of hydroboration reaction between aldehyde and borane. The trisilazane-rare earth complex disclosed by the invention can be used for catalyzing the hydroboration reaction between aldehyde and borane in a high activity manner under a mild condition (room temperature), and the dosage of a catalyst is only 0.1%-0.5% of molar ratio of aldehyde; the reaction speed is very high, the yield higher than 90% can be achieved after 10 minutes of reaction; compared with existing catalytic systems, the application has the advantages that the dosage of the catalyst is reduced, the yield is increased, the required time is short, the reaction condition is mild, and atom economy synthesis is highly met.

The invention discloses a preparation method of a graphene-graphene oxide nano-composite material modified electrode, which comprises the following steps of: a, preparing a graphene-graphene oxide nano-composite material; b, processing the electrode; and c, preparing a GR-GO modified electrode (GR-GO/GCE). According to the preparation method of the graphene-graphene oxide nano-composite material modified electrode provided by the invention, graphene is dispersed well, therefore, good performances of graphene are ensured; the material is simple and convenient to synthesize; and preparation of the electrode is simpler, more convenient and free from toxicity and environmental pollution.

The invention discloses a long chain quinoline hydrazone gel factor, wherein the long chain quinoline hydrazone gel factor can form stable organic metal gel when being dissolved in such organic solvents with copper ions as DMF (Dimethyl Formamide), and the organic metal gel has no fluorescence. When an aqueous solution of CN<-> is added into the organic metal gel, the color of the gel changes and green fluorescence is generated at the same time, while similar color and fluorescence phenomena cannot be generated when adding other anions. Therefore, L1-Cu<2+> organic metal gel can be used for singly and selectively performing colorimetric-fluorescence recognition on CN<-> in water, and other anions generate no interference on the recognition process, thereby capable of being used for conveniently and quickly detecting cyanide ions. The strong metal gel is good in stability, liable to store and carry and convenient to use, thereby having potential application value.

The DNA sequencing method using a sulfooligonucleotide probe further lower the sequencing cost, lengthen the sequencing length of each sequence, and shorten the reading time of each base. By a sulfonucleotide-contained sequencing primer, employing a hybrid- enzyme connection - enzyme cutting high throughput DNA sequence technology, the invention provides a new method for DNA sequence analysis, establishing a rapid, precise and low-cost high throughput DNA sequence technology. The most advantage of the invention is realizing simple synthesis of maker hybrid sequence tested by DNA sequence and convenient cutting of maker. Since the hybrid high throughput primer is synthesized and purified by a very mature solid-phase DNA method, the method has no accumulative effect of erroneous extension and is capable of keeping the quantity of DNA template and sequencing primer, and the sequencing is reliable and correct.

The invention provides a method for synthesizing an anastrozole intermediate-2,2'-(5-methyl-1,3-phenylene)-bis-(2-methyl propionitrile), which comprises the following steps: dissolving a cyanoacetate derivative and 3,5-dihalogenated toluene in a solvent, carrying out decarboxylation cyanomethylation reaction under the action of a palladium catalyst and an organic phosphorus ligand, obtaining a target product, or obtaining 2,2'-(5-methyl-1,3-phenylene)-bis-(acetonitrile), and further being reacted with halogenated methane or methane which is ready to be halogenated in the presence of a strong base hydride, and generating the target product. The method for synthesizing the intermediate can avoid the use of highly toxic cyanide, and has the advantages of cheap price and easy obtainment of raw materials, easy synthesis, no side reactions and high yield.

The invention discloses a preparation method of a responsive polymeric ionic liquid hydrogel and a swelling test thereof. The method firstly synthesizes ionic liquid by using vinyl imidazole as a rawmaterial; 2) then using the ionic liquid prepared in step 1) as a monomer, N, N-methylene bisacrylamide as a crosslinking agent and azobisisobutyronitrile as an initiator, and synthesizing by a monomer cross-linking polymerization method. In the view of the problems of single monomer type, poor swelling property, slow response and the like of a traditional monomer, the method designs and synthesizes two ionic liquid according to the characteristics of easy design of the ionic liquid, hopes to prepare a rapid-response homopolymeric hydrogel with multiple responsiveness and the like, studies swelling behaviors, and extends polyelectrolyte hydrogel swelling kinetic models.

The invention is directed to a process for the separation of oxygen from an oxygen containing gas using an oxygen selective material comprising a transition element complex comprising a first transition element ion and one or more chelating ligands, wherein:i) said first transition element ion is capable of accepting intermolecular donation;ii) said chelating ligand or ligands provides up to four intramolecular donor sites to said transition element ion;iii) said chelating ligand or ligands provides an intermolecular donor site to a second transition element ion which is contained in second discrete transition element complex; andiv) said chelating ligand or ligands contains at least one substituent that inhibits mu-peroxo dimer formation on said sorbent;wherein when said material is in deoxy form, the total number of donor sites to said first transition element ion is five.

The invention discloses N-methyl, N-carboxymethyl dithiocarbamic acid chelating resin and its preparation method. The resin contains functional group-N-methyl, N-carboxymethyl dithiocarbamic acid group. The preparation method includes the following steps: using styrene as monomer, di-ethylene benzene as cross-linking agent, liquid wax as porosifer, magnesium carbonate as dispersant, benzoyl peroxide as initiator, zinc chloride as catalyst in chloromethylation process to react with chloro-methyl ether to gain chlorine ball with different chlorinity; then adding N-methyl, N-carboxymethyl dithio-amino sodium formate reagent to gain series N-methyl, N-carboxymethyl dithio-amino formyloxy chelating resin which has the advantages of easy synthesis, stable performance, high selectivity for heavy metal, wide application prospect in mineral product metallurgy producing mother liquor purifying, heavy metal production waste water harnessing reclaiming fields etc.

The invention discloses a 360-degree panoramic camera module. The 360-degree panoramic camera module comprises a front-facing fish-eye lens, a rear-facing fish-eye lens and an image processor, wherein the front-facing fish-eye lens and the rear-facing fish-eye lens are arranged back to back, and field angles of the front-facing fish-eye lens and the rear-facing fish-eye lens are greater than or equal to 180 degrees; the image processor is used for synthesizing a first image taken by the front-facing fish-eye lens and a second image taken by the rear-facing fish-eye lens into one 360-degree panoramic image; an optical center of the front-facing fish-eye lens and an optical center of the rear-facing fish-eye lens are positioned on the same axis; and the image processor is connected with the front-facing fish-eye lens and the rear-facing fish-eye lens. In the 360-degree panoramic camera module, the front-facing fish-eye lens and the rear-facing fish-eye lens are designed in a back-to-back way, so that the aim of 360-degree all-angle-of-view shooting can be fulfilled instantly. Meanwhile, the optical centers of the front and back fish-eye lenses are positioned on the same axis, namely, central optical axes of the front and back fish-eye lenses are consistent, so that a difference between the taken images can be avoided, and the image processor can perform image synthesis processing more conveniently. The invention also discloses electronic equipment.

The invention discloses an organic solar cell with a cyclopentyl bithiophene derivative as an electron acceptor. The organic solar cell includes a substrate, a cathode, a cathode modification layer, an active layer, an anode modification layer, and an anode. The active layer is a blend membrane of an electron donor and an electron acceptor, wherein the electron donor is PBDB-T, and the electron acceptor is a cyclopentyl bithiophene derivative DFPCIC. By making use of the good molecular planarity and appropriate energy level structure characteristic of DFPCIC, the organic solar cell of the invention has high open-circuit voltage, short-circuit current density and fill factor, and has energy conversion efficiency (PCE) up to 10.14%. Meanwhile, the organic solar cell based on PBDB-T: DFPCIC exhibits excellent thermal stability. In addition, DFPCIC is easy to synthesize, and is beneficial to reducing the cost of the organic solar cell.

The invention discloses a preparation method and an application of a sodium-ion-embedded manganese dioxide/nitrogen-doped porous carbon composite material, relates to a preparation method and an application of a manganese dioxide composite material, and aims to solves the problems of poor rate capacity and low capacitance retention rate when manganese dioxide is used as an electrode material of apseudo-capacitor type supercapacitor. The method comprises the following steps: 1, preparing n-dodecahedron ZIF-67; 2, preparing a ZIF-67-derived nano-porous carbon material; and 3, performing compounding to obtain the sodium-ion-embedded manganese dioxide/nitrogen-doped porous carbon composite material. The sodium-ion-embedded manganese dioxide/nitrogen-doped porous carbon composite material is used as a positive electrode material of a supercapacitor. According to the method, the sodium-ion-embedded manganese dioxide/nitrogen-doped porous carbon composite material can be obtained.

A solid state ion conducting electrolyte and a battery incorporating same. The electrolyte includes a polymer matrix with an alkali metal salt dissolved therein, the salt having an anion with a long or branched chain having not less than 5 carbon or silicon atoms therein. The polymer is preferably a polyether and the salt anion is preferably an alkyl or silyl moiety of from 5 to about 150 carbon/silicon atoms.

The invention relates to a method for preparation of 1, 4-substituted 1, 2, 3-triazole from an organic azide compound and (Z)-beta-alkenylbromide and a use thereof and belongs to the technical field of preparation of 1, 4-substituted 1, 2, 3-triazole. The method comprises that an organic azide compound (1) and (Z)-beta-alkenylbromide (2) as raw materials undergo a reaction at a certain temperature in the presence of an organic solvent-copper catalyst-alkali system to produce a product and the product is separated and purified. The method has the advantages of raw material easy availability, low cost, less pollution, high yield, simple post-treatment process, high product purity and mild reaction conditions, and is suitable for industrial production.

The invention belongs to the technical field of catalytic materials, and relates to a preparation method and application of a triphenylamino metal organic framework compound capable of catalyzing carbon dioxide-epoxy compound cycloaddition. The preparation method comprises the following steps: 1. adding a connection ligand L and a transition metal salt Tm in a mole ratio of 1:(3-5) into a mixed solvent composed of ethanol and N,N-diethyl formamide in a volume ratio of 1:(2-2.5) or a mixed solvent composed of concentrated nitric acid and N,N-dimethylformamide in a volume ratio of 1:(6-8), and uniformly stirring; and 2. putting the solution prepared in the step 1 into a drying oven, drying for 60-90 hours while controlling the temperature at 60-120 DEG C, shutting down the drying oven, cooling to room temperature to precipitate a crystal, filtering and drying to obtain the target material Tm-L. The catalyst synthesis process is simple and easy to operate, and has the advantages of low raw material price for the catalyst and catalytic reaction, and high yield. The obtained functional material has stable chemical properties, and can easily implement large-area popularization and application.

The invention relates to a preparation method of a visible-light catalyst, and belongs to preparation methods of catalysts. The visible-light catalyst is of a composite structure of cobalt phosphate Co3(PO4)2 nanosheets and silver phosphate Ag3PO4 nanoparticless and is prepared by adopting a chemical segregation method which comprises the following steps of preparing a mixed solution of silver nitrate AgNO3 and cobalt nitrate Co(NO3)3 in advance, and then dropwise adding a diammonium hydrogen phosphate (NH4)2HPO4 solution until a large amount of precipitation is generated. In the process of degrading methyl orange by visible light, compared with pure silver phosphate Ag3PO4 with the same quality, the composite structure has the advantage that both the stability and the photooxidation activity are obviously improved. The composite structure can be used for processing and degrading dye wastewater such as methyl orange and photolyzing water to prepare hydrogen or oxygen, and when sunlight is captured, photon-generated carriers are effectively promoted to transfer. The composite structure has the advantages of large effective surface area, simplicity in synthesis and good interfacial lattice matching and is favorable for improving the catalytic activity, and the photocatalytic activity can be further optimized by controlling the proportion of two components.