267 results about "Alkoxy group" patented technology

Disclosed is a liquid crystal composition. The liquid crystal composition includes liquid crystal molecules including at least one of a liquid crystal compound having an alkenyl group and a liquid crystal compound having an alkoxy group, and a first stabilizer including a compound having a structure represented by Formula 1:where n is 0 or 1; m is 0 or 1; k is 0 or 1; Z1, Z2, and Z3 are each independently a single bond, —C═C—, —OCO—, —COO—, —CF2O—, or a C1 to C5 alkylene group; X1, X2, X3, and X4 are each independently hydrogen or halogen; Y is hydrogen, an alkylene group, an alkoxy group, a hydroxyl group, —NHCOCH3, or ═O; and A and B are cyclic compounds.

This invention relates to the use of compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, in the treatment or prevention of mycobacterial infections, wherein: one of R2 and R3 is H, and the other is (CR) a R b ) n Y; Y is selected from CO2R c CN and CONR e R f R4 is selected from H, halogens, CN, alkyl and alkoxy groups; R6 is selected from H, F, Br, I, COOH, CN, COR. d CO2R d Alkyl, haloalkyl, alkoxy, haloalkoxy, nitro, OH, SR d SOR d SO2R d SO2NR d R d NHSO2R d aryl and heteroaryl groups, wherein the aryl or heteroaryl group is optionally substituted by one or more substituents selected from alkyl, alkoxy, halogen, haloalkyl, and haloalkoxy groups; R7 is selected from H, halogen, alkyl, and alkoxy groups; R9 is selected from H, COR... d Alkyl, haloalkyl, aryl, CO-aryl, CO-haloaryl, aralkyl and haloaralkyl; R1, R5 and R8 are H; each R a R b R c R d R e and R f The compounds are independently selected from H, alkyl, and haloalkyl groups; n is 1 to 6. Other aspects of the invention relate to subgroups of compounds of formula (Ia), pharmaceutical compositions comprising such subgroups, and their use in the treatment or prevention of mycobacterial infections.

This invention belongs to the field of organic synthesis and relates to a nitrogen-containing [3,2-b]indole derivative, its preparation method, and its application. The nitrogen-containing [3,2-b]indole derivative is a compound, optical isomer, or pharmaceutically acceptable salt thereof, as shown in the following structure: ; wherein R1, R2, R3, and R4 are independently selected from hydrogen atoms, halogens, cyano groups, C1-C8 alkyl groups, and C1-C8 alkoxy groups; R5, R6, R7, and R8 are independently selected from hydrogen atoms, halogens, and C1-C8 alkyl groups; R9 is selected from C1-C8 alkyl groups; when R1, R2, R3, R4, R5, R6, R7, and R8 are all hydrogen atoms, R9 is selected from C1-C2 alkyl groups. The compound exhibits antitumor activity, particularly against HeLa cervical cancer, showing a significant inhibitory effect on its proliferation.

Provided is a photosensitive resin composition that contains (A) a photopolymerizable compound that has an ethylenically unsaturated group and an acidic substituent, (B) at least one of a silane coupling agent that has a (meth)acryloyl group and an alkoxysilyl group and a component derived from a silane coupling agent that has a (meth)acryloyl group and an alkoxysilyl group, (C) a thermosetting resin, and (D) an organic peroxide, the (C) thermosetting resin containing at least one of a maleimide resin and an allyl resin. Also provided are a photosensitive resin film that uses the photosensitive resin composition, a printed wiring board and a production method for the printed wiring board, and a semiconductor package.

A low-modulus, high-resilience modified alcohol-based silicone sealant, its preparation method, and its application are disclosed, relating to the field of sealant materials technology. The silicone sealant comprises the following components in parts by weight: 100 parts of α,ω-alkoxysilane ethylidene-terminated polydimethylsiloxane, 30-80 parts of plasticizer, 80-150 parts of reinforcing filler, 0.5-20 parts of silane crosslinking agent, 0.5-10 parts of silane tackifier, and 0.01-1 part of Lewis acid catalyst; wherein the plasticizer is α-alkoxysilane ethylidene-terminated polydimethylsiloxane. The low-modulus, high-resilience silicone sealant of this invention exhibits fast surface drying speed, low modulus, high elastic recovery rate, good adhesion, and weather resistance.

The application provides a kind of sodium sulfide nine hydrate and activated olefin / acetylene preparation polyether and its method, belong to sulfur-containing polymer technical field.The structural formula of polyether in the application, R 1 And R 2 Independently be substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl;The number of carbon atoms of the alkyl is 1-10, the number of carbon atoms of alkoxy is 1-10, the number of carbon atoms of aryl is 1-30, the number of carbon atoms of heteroaryl is 3-30;Substituted alkyl and substituted alkoxy independently are one or more;N is an integer of 2-4000.The application is used as sulfur source sodium sulfide nine hydrate, under the condition of no metal catalyst, polyether is synthesized by polymerization reaction;Reaction condition is mild, reaction is efficient, economic and environmental protection, meet the current green production concept and can avoid the use of dangerous reagent.

The present disclosure relates to a polyorganosiloxane comprising the following structural formula: X—[Si(R1)2O]—[Si(R2)2O]m—[SiR2CaH2a+1O]n—[Si(R1)2]—X, where a is an arbitrary integer between 6 and 18, n is an arbitrary number between 0.7 and 20, m is an arbitrary number between 10 and 1500, m / n is an arbitrary number greater than 20, R1 or R2 is a C1-C5 alkyl group, X represents one or more groups selected from among C2-C6 alkenyl, alkoxy, hydroxyl and hydrogen. The polyorganosiloxane can significantly lower the viscosity, and improve the flowability and processability, of the resulting silicone composition, compared with other polyorganosiloxanes at the same thermally conductive filler loading. Meanwhile, for thermally conductive silicone compositions with the same viscosity, the polyorganosiloxane used as the base polymer can accept a significantly higher level of the thermally conductive fillers, thereby improving their thermal conductivity.

This invention provides an organosilicon sealant composition for anti-fog automotive lights and its preparation method. The organosilicon sealant composition for anti-fog automotive lights comprises the following components: α,ω-dihydroxy polydimethylsiloxane, a first crosslinking agent, a second crosslinking agent, a catalyst, a filler, a coupling agent, and a plasticizer. The first crosslinking agent has 3 alkoxy functional groups, the second crosslinking agent has ≥4 alkoxy functional groups, and the D3-D10 content of α,ω-dihydroxy polydimethylsiloxane is 0.01-0.05 wt%. This invention utilizes a polyalkyloxysilane derivative prepared from a tertiary amine polyol and an isocyanate-based silane coupling agent as a non-volatile second crosslinking agent, which has high activity, does not reduce the reaction rate, and can reduce the amount of the volatile first crosslinking agent. Furthermore, using α,ω-dihydroxy polydimethylsiloxane with a low D3-D10 content as the base adhesive can further reduce volatile components, making the automotive lights less prone to fogging.

To provide a topcoat paint composition that can achieve both weather resistance, opacity, and appropriate flexibility in the formed coating film. [Solution] The topcoat paint composition comprises a main component and a curing agent, wherein the main component comprises at least a resin (A), a resin (B), a pigment, and a solvent, the resin (A) is an acrylic polyol resin having a hydroxyl value of 30 mgKOH / g or more and less than 100 mgKOH / g of resin solids, the resin (B) is an alkoxysilyl group-containing acrylic resin having a hydroxyl value of 0 mgKOH / g or more and less than 30 mgKOH / g of resin solids, and the silicon content in the resin solids is 5% by mass or more and 30% by mass or less in terms of SiO2, the curing agent comprises at least a polyisocyanate, the mass ratio of resin (A) to resin (B), (A):(B) is 80:20 to 20:80, and the pigment content is 5% by mass or more and 50% by mass or less, the topcoat paint composition.

Provided are a compound having serotonin 5-HT2A receptor antagonism and / or inverse agonism, a pharmaceutically acceptable salt thereof, and a composition for serotonin 5-HT2A receptor antagonism and / or inverse agonism comprising them.A compound represented by Formula (I):wherein R1 is substituted or unsubstituted aromatic heterocyclyl or the like; R2 is each independently a hydrogen atom or the like; R3 is each independently a hydrogen atom or the like; n is 1 or the like; a combination of (L1, L2) is (NH, N) or the like; R4 is a group represented by Formula:wherein p and q are each independently 2 or the like; Ra is substituted or unsubstituted alkyl or the like; Xb is each independently CRbRb′; Rb is each independently a hydrogen atom or the like; Rb′ is each independently a hydrogen atom or the like; Xc is each independently CRcRc′; Rc is each independently a hydrogen atom or the like; Rc′ is each independently a hydrogen atom or the like; Xd is CRd or the like; and Rd is a hydrogen atom or the like; R5 and R6 are each independently a hydrogen atom or the like; and R7 is a group represented by Formula:wherein A is CR11 or the like; R9 is substituted or unsubstituted alkyloxy or the like; R10 is a hydrogen atom or the like; and R11 is each independently a hydrogen atom or the like; or a pharmaceutically acceptable salt thereof.

The present disclosure provides an ionizable lipid that can be used for nucleic acid delivery into cytoplasm.An ionizable lipid of the present disclosure is, for example, a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof.whereinL1 represents —(CH2)n—,L2 represents —(CH2)m—,n represents an integer of 1 to 5,m represents an integer of 1 to 5,X1 and X2 each independently represent —OC(O)— or —OC(O)O—,Y represents —OC(O)—, or —OC(O)O—,R1 and R2 each independently represent an alkyl group having 2 to 25 carbon atoms or alkenyl group having 2 to 25 carbon atoms that is optionally substituted with one or more of alkoxy groups having 4 to 12 carbon atoms, R1 or R2 each have a total of 4 to 30 carbon atoms, andP is represented by the following formula P-1 or formula P-2, andR3 represents an alkyl group having 1 to 5 carbon atoms that is optionally substituted with a hydroxy group,R4 and R5 each independently represent a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, or R4 and R5 are taken together to form an alkylene group having 2 to 5 carbon atoms,p represents 0 or 1, q represents an integer of 0 to 2, R6 and R7 each independently represent an alkyl group having 1 to 5 carbon atoms,r represents an integer of 1 to 5, and* represents a linking site.

The application discloses a preparation method of silica with controllable particle size and morphology, and comprises the following steps: 1) mother liquor preparation: uniformly mixing an organic solvent, an alkali catalyst, an acid catalyst and water; 2) B liquid preparation: mixing alkoxy silane and the organic solvent, and stirring for a period of time; 3) particle nucleation: using a peristaltic pump to immerse a feed redistributor into the mother liquor, adding the B liquid into the mother liquor, and performing a silica particle nucleation reaction to obtain a seed solution; 4) particle regrowth: adding water and the alkali catalyst into the seed solution obtained in the step 3) and uniformly stirring; continuously adding the mixed solution of the alkoxy silane and the organic solvent into the seed solution by using the feed redistributor, and performing particle regrowth under stirring; 5) concentration and filtration: performing heating concentration on the sample, removing the organic solvent in the sample, and removing large particles in the sample by filtration. The application can finally control the particle size and morphology of the silica sol by effectively regulating the discharging mode and feeding position of the feed redistributor, and regulating the redistribution state of the feeding liquid in the mother liquor.

A glass bonding composition includes a urethane prepolymer, flow regulator, cellulose nanofiber, dispersant, and clay to reduce sag when bonding heavy glass. The composition, containing about 2.2-6 wt % cellulose nanofiber and about 0.2-1.3 wt % dispersant, forms a coating layer that exhibits a thickness increase of about 4 mm or less under a 500 gf tensile load after 1 hour of moisture curing. The cured layer also provides a shear bonding strength of about 3 MPa or more when tested at 50 mm / min with a 250 mm2 bonding area. Optional alkoxysilane-based bonding promoters improve adhesion to glass without compromising performance, making this composition suitable for bonding glass to various substrates, including painted members.

The present disclosure provides a one-component room temperature vulcanizable (RTV) silicone sealant composition comprising an alkoxy-terminated organopolysiloxane polymer (a) and a tin-based catalyst (d), and a process for preparing said one-component room temperature vulcanizable (RTV) silicone sealant composition comprising an alkoxy-terminated organopolysiloxane polymer (a) and a tin-based catalyst (d). The one-component room temperature vulcanizable (RTV) silicone sealant composition relies on a novel stabilizer combination (e) of (e)(i) one or more silazanes and one or more silanes (e)(ii) having at least one acetamide group, with the aim of providing a storage-stable one-component room temperature vulcanizable (RTV) silicone sealant composition.

Methods for forming a vapor deposition precursor are provided. The method comprises contacting an aluminum halide compound, an alkoxy aluminum compound, and a Grignard reagent to form the vapor deposition precursor. The vapor deposition precursor comprises an dialkyl aluminum alkoxide compound. The vapor deposition precursor is formed without use of a pyrophoric compound. Related compositions, related precursors, and related methods are also provided, among other things.

The Invention relates to a method Method for making a ruthenium catalyst comprising the steps of - Providing an aromatic dithiol substituted on adjacent aromatic carbon atoms with thiol groups, wherein in a first step an aromatic compound substituted with two leaving groups on adjacent aromatic carbon atoms are reacted with alkali trithiocarbonate to obtain an aromatic benzodithiole-thione, which in a subsequent step is reacted / hydrolysed with a base; - providing a zinc dithiolate compound by reacting the aromatic dithiol with a zinc carboxylate in an organic solvent; Reacting the zinc dithiolate compound with a ruthenium compound wherein X1 and X2 are, independently of each other, are anionic ligands and are the same or different; L and L2 are, independently of each other, neutral electron donor ligands and are the same or different; Ar is an aromatic group which may be substituted and that can be bridged with L, if L is an alkoxy group; - Obtaining a ruthenium catalyst of formula 4 or 4a, wherein R1 to R4 are, independently of each other, are selected from hydrogen, halogen, alkyl, aryl, or R.1 with R3, R3 with R4 or R2 with R4 are forming together an aliphatic or aromatic ring.

The present application provides a compound used as a coating agent for providing a particle having excellent dispersibility and refractive index, a particle having a surface coated with the compound, a production method thereof, and a dispersion composition containing the particle. The compound according to the present application has a structure represented by Formula (1). In the formula, R 1 represents an organic group having 1 to 30 carbon atoms, R 2 represents OR 3 or a group represented by Formula (2), R 3 represents an organic group having 1 to 30 carbon atoms, n1 and n2 represent an integer of 0 or more, n1 + 2 x n2 represents a valence number determined by the kind of L, L represents aluminum, gallium, yttrium, titanium, zirconium, hafnium, bismuth, tin, vanadium, or tantalum, * represents a bonding site, and R 4 and R 5 represent an organic group having 1 to 30 carbon atoms which can have an oxygen atom. The particle according to the present application has a structure represented by Formula (1) on the surface.

The disclosure provides for coalescent agents having low VOC formed using alcohol initiators with ethylene oxide groups in an alkoxylation process. The coalescent agents are used in an aqueous coating composition that includes a binder; water and the coalescent agent represented by Formula (I). For the coalescent agent of Formula I, R1 is a linear C6-C16 alkyl or a branched C6-C16 alkyl, R2 is independently a methyl or an ethyl; x has an average value of 0 to 10; y has an average value of 0.25 to 5;z has an average value of 3 to 20; a ratio of y / z is from 0.01 to 0.5.

The present invention addresses the problem of providing a composition capable of transferring fine and densely mounted semiconductor chips with high positional accuracy. The solution to the aforementioned problem is a composition containing a compound (a) and a compound (b), wherein the compound (a) accounts for more than 50 mass% and no more than 95 mass% relative to 100 mass % of the solid content of the composition.　The compound (a) has two or more groups bonded by reacting with a crosslinking group of the compound (b) per molecule, has maximum absorption in any wavelength within the range of 240 to 400 nm, and has a gram absorption coefficient of 40 to 4000 L / (g·cm) at the maximum absorption wavelength. The compound (b) does not correspond to the compound (a) and has two or more crosslinking groups per molecule, the crosslinking groups being groups selected from the group consisting of epoxy groups, oxetanyl groups, alkoxymethyl groups, methylol groups, and isocyanate groups.

The invention concerns a compound of formula (Ia) or (Ib) wherein R1 is hydrogen or a methyl group; R2 is an unsubsti- tuted or substituted alkyl group; R3 is an aryl group or a heteroaryl group, optionally substituted by one or more groups selected from halogen, alkyl or alkoxy; and, in Formula (Ia), X is CH or N and Y is NH, S or O, or, in Formula (Ib), X is NH, S or O and Y is CH or N. The invention further concerns a method of synthesiz- ing the inventive compound, a composition comprising the inven- tive compound or a pharmaceutically acceptable salt thereof and bedaquiline (BDQ), an analogue of bedaquiline (BDQ) or a mix- ture thereof, and the use of said composition or compound for the treatment of tuberculosis.

The application discloses a synthesis method of C3-substituted quinoxaline ketone derivatives and application thereof. A series of C3-substituted quinoxaline ketone derivatives with both terpene and quinoxaline ketone biological activity skeletons are obtained by using N-alkoxy phthalimide and quinoxaline ketone as starting substrates, under the catalysis of a photocatalyst and visible light irradiation, and at a temperature of 55-65 DEG C for 10-15 h. The application has the advantages of stable and easy-to-prepare raw materials, mild reaction conditions, simple experimental operation, good chemical selectivity and functional group tolerance, and is a green chemical synthesis method with good application prospect. The activity experiment results show that the synthesized C3-substituted quinoxaline ketone derivatives have good inhibiting effect on the growth of plant pathogenic fungi.

This invention belongs to the field of organic ligand technology, and specifically discloses a phosphoxazolin ligand having the structure shown in general formula I or general formula II, or its tautomers, enantiomers and diastereomers: , R 1 Selected from hydrogen, alkyl, perfluoroalkyl, alkoxy, aryl; R 2 Selected from hydrogen, alkyl, perfluoroalkyl, alkoxy, aryl; R 3 Selected from alkyl, cycloalkyl, alkenyl, and aryl; R 4 Selected from alkyl, cycloalkyl, alkoxy, perfluoroalkyl, aryl, and fluorine atoms; R 5 Selected from hydrogen, alkyl, cycloalkyl, alkoxy, perfluoroalkyl, aryl, and fluorine atoms; R 6 The substituents are selected from hydrogen, alkyl, cycloalkyl, alkoxy, perfluoroalkyl, aryl, and fluorine atoms; n and m are the number of substituents, where n+m≤5. This invention also discloses a method for preparing phosphosoxazoline ligands and their application in catalytic allylation, bicyclization, intermolecular desymmetry, or intramolecular condensation reactions of nitrile derivatives.

The present invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, Y is CH2 or O, R1 is an alkyl, alkoxy, alkenyl, alkenyloxy, cycloalkyl, or cycloalkyloxy which may have a substituent, R2 is independently selected from halogens and alkyls, and R3 is independently selected from halogens and alkyls)

The present invention aims to provide silica particles, silica sols, and polishing compositions that are less likely to cause defects in the object to be polished. The present invention relates to silica particles that satisfy the following formula (1), where x (mass%) is the mass percentage of alkoxy groups in the silica particles and y (mass%) is the mass percentage of silanol groups in the silica particles. y(mass%)< 8x(mass%)+0.5 (1)

The invention relates to an admixed wet hydraulic composition (ABCD) comprising: (A) a hydraulic binder composition comprising: (.A.1.) lime and / or clinker, (.A.2.) and a mineral addition; (B) an admixture comprising: (.B.1.) a water-reducing or high-range water-reducing admixture chosen from polyalkoxylated polycarboxylates, (.B.2.) a water-reducing or high-range water-reducing admixture chosen from polyalkoxylated phosphonates, (.B.3.) a rheological agent, (.B.4.) a calcium salt, (.B.5.) a defoamer and / or at least one air-entraining agent, and (.B.6.) a biocidal agent; (C) water; (D) an aggregate. ABCD has a viscosity suitable for the handling and forming thereof, an appropriate setting time, and mechanical properties at all ages and the durability, in hardened form, are satisfactory.

Provided is a polyamide resin composition comprising a polyamide resin (A) and a phenolic compound (B), wherein the phenolic compound (B) is at least one compound selected from the group consisting of triphenolic compounds (B-1) represented by general formula (1) (wherein R1, R2, R3, R4, R5, and R6 are each independently a hydrogen atom, a halogen atom, a C1-C5 alkyl group, or a C1-C5 alkoxy group) and phenolic compounds (B-2) having a dicyclopentadiene-derived skeleton.

The present invention addresses the problem of providing a cosmetic that has high coating film uniformity and a high secondary adhesion-less effect, and that is excellent in makeup durability.　A cosmetic that solves the problem to be addressed by the present invention is characterized by containing a polyorganosiloxane having a block structure. The polyorganosiloxane is characterized by: being represented by general formula (1); having a weight average molecular weight of 500,000 or greater; and, when at room temperature and containing no solvent, constituting a solid that has a softening point of 50°C or higher. (In the formula: R1, R2, R3, R4, and R5 are C1-20 saturated or unsaturated hydrocarbon groups that may have a hydrogen atom or a substituent; m indicates the number of repetitions of diorganosiloxy units, where 50≥m≥0 is satisfied; a, b, c, d, and e indicate the abundance mole fractions of the respective diorganosiloxy units, where 0.3≥a≥0, 0.3≥b>0, 0.5≥c≥0, 0.95≥d>0.5, 0.3≥e≥0, and a+b×(2+m)+c+d+e=1 are satisfied; and x and y are the numbers of hydroxy groups or alkoxy groups bound to the diorganosiloxy units a-e per mol of Si atoms, where 0.1 ≥ x > 0 and 0.1 ≥ y > 0 are satisfied.)

The application relates to the technical field of chemical synthesis, and discloses a synthesis method of small-molecule polyethylene glycol, wherein the synthesis method comprises the following steps: preparing an alcohol-oxygen ligand initiator by alkoxyl exchange of 2-methoxyethanol and triisobutyl aluminum; mixing the alcohol-oxygen ligand initiator with liquid ethylene oxide through a T-shaped micro-mixer, and then introducing the mixture into a tubular micro-reactor to perform sectional temperature control polymerization; chelating and de-aluminum through disodium ethylenediaminetetraacetate, and then removing solvents through reduced pressure distillation; and removing double-hydroxyl polyethylene glycol impurities through n-hexane cooling crystallization to obtain small-molecule monomethoxypolyethylene glycol products.

The present disclosure relates to a method for preparing methyl propionate from ethylene or C2 mixed gas, comprising the following steps: mixing a heterogeneous catalyst with a liquid acid to obtain a mixed catalyst; the heterogeneous catalyst comprises a Pd precursor, a phosphine ligand and an acidic molecular sieve; the pH of the liquid acid is greater than or equal to 4; the content of the liquid acid in the mixed catalyst is 500-3000 ppm; pure ethylene or C2 mixed gas, CO and methanol are contacted with the mixed catalyst to carry out the reaction of ethylene alkoxycarbonylation to prepare methyl propionate, to obtain a liquid phase mixed product containing methyl propionate and an optional gas phase product containing ethane; wherein the C2 mixed gas comprises ethylene and ethane. The present disclosure replaces the homogeneous catalyst with the heterogeneous catalyst, develops a process for preparing high-value-added methyl propionate from widely available ethylene and low-cost C2 mixed gas, and can realize large-scale industrial production.

A film-forming composition is provided, configured for forming a low-k material film with reduced plasma-induced damage susceptibility. The film-forming composition comprises a silicon precursor having a structure according to general formula (1): (1), wherein X is selected from O atoms, NH groups, and CH2 groups; and R 1 R 2 R 3 R 4 R 5 and R 6 Each is an independent substituent selected from hydrogen atoms, C1-C6 alkyl, C2-C6 alkenyl, and C1-C6 alkoxy groups, provided that R 1 R 2 R 3 R 4 R 5 and R 6 At least one of them is a methyl group (CH3). Preferably, R 1 R 2 R 3 R 4 R 5 and R 6 At least two of them are methyl groups. A method and system for forming low-k material films on the surface of a substrate using a PE-CVD method are also provided.