The invention belongs to the technical field of bio-printing, and particularly discloses bio-ink of light-curable
Matrigel matrigel, a preparation method and application in volume bio-printing.The bio-ink is prepared by mixing hydrogel and
Matrigel matrigel and then adding a
photoinitiator, controllable curing can be achieved under
irradiation of a
light source, and the bio-ink has the advantages that the bio-ink can be applied to volume bio-printing; the problem that in the prior art, due to the fact that
Matrigel matrigel lacks photosensitive groups, photo-crosslinking reaction cannot be carried out is solved, the bio-ink is further mixed with a biological medium, the composite bio-ink is obtained and perfectly compatible with the GLVBP technology, a printed and formed structure has high precision,
high cell viability and good
biocompatibility, and the composite bio-ink can be used for preparing the light-sensitive matrix gel. The method has a wide application prospect in the biomedical fields of
organoid culture,
tissue engineering and the like.