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Biological electrospinning 3D printing device adopting low-temperature molding and preparation method for biological electrospinning 3D printing device

A 3D printing and biological technology, applied in processing and manufacturing, additive processing, etc., can solve problems such as low viscosity and poor structural formability, achieve convenient operation, improve printing formability, and solve the effects of poor formability

Pending Publication Date: 2019-11-19
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at the same time, due to the refinement of printing, there are higher requirements for printing materials. The materials must have good uniformity and low viscosity, but this makes the formability of the printed structure poor.

Method used

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  • Biological electrospinning 3D printing device adopting low-temperature molding and preparation method for biological electrospinning 3D printing device
  • Biological electrospinning 3D printing device adopting low-temperature molding and preparation method for biological electrospinning 3D printing device

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Experimental program
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Effect test

Embodiment 1

[0030] Such as Figure 1-2 As shown, the novel bio-electrospinning 3D printing device adopting low-temperature molding according to the embodiment of the present invention and its preparation method include a casing 1 and a protective cover 2 located on the outer wall of the casing 1, and the top of the casing 1 is provided with a There is a printing nozzle moving platform 3 arranged horizontally and horizontally, the bottom end of the printing nozzle moving platform 3 is provided with a matching printing nozzle 4, and the printing nozzle moving platform 3 is sleeved on the top of the printing nozzle 4 There is a barrel 5 matching it, and a heating jacket 6 matching it is set on the barrel 5, and one side of the housing 1 is provided with an air pressure squeezer with the electrical connection point of the barrel 5. out of the system 7, and the bottom end of the casing 1 and below the print nozzle 4 is provided with a printing platform 8, and the upper cover of the printing pl...

Embodiment 2

[0032] Such as Figure 1-2 As shown, a heat-conducting and insulating ceramic is provided between the cooling platform 9 and the printing platform 8 to avoid the influence of the electric field while cooling. The printing nozzle moving platform 3 controls the horizontal movement of the X-axis and the Y-axis of the printing nozzle 4, so The negative pole of the high voltage electrostatic generator 10 is electrically connected to the printing platform 8 .

[0033] In order to understand the above-mentioned technical solution of the present invention more clearly, the above-mentioned solution of the present invention will be described in detail below through specific examples.

[0034] The preparation of the low-temperature forming bio-electrospinning 3D printing device includes the following steps:

[0035] Step S101, adding polymer material or cell hydrogel material into barrel 5;

[0036] Step S103, the heating jacket 6 heats the molten material, and the cell hydrogel materi...

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Abstract

The invention discloses a biological electrospinning 3D printing device adopting low-temperature molding. The biological electrospinning 3D printing device comprises a shell and a protection hood located on the outer wall of the shell, wherein the inner top end of the shell is provided with a printing spray-head movement platform horizontally arranged in the horizontal direction, the bottom end ofthe printing spray-head movement platform is provided with a printing spray head matched with the printing spray-head movement platform, the position, on the printing spray-head movement platform, located at the top end of the printing spray head is provided with a material barrel matched with the printing spray head in a sleeved manner, the material barrel is provided with a heating sleeve matched with the material barrel in a sleeved manner, one side of the inner portion of the shell is provided with an air pressure extrusion system in electrical connection with the material barrel, and theposition, at the inner bottom end of the shell, located below the printing spray head is provided with a printing platform. The biological electrospinning 3D printing device adopting the low-temperature molding and a preparation method for the biological electrospinning 3D printing device have the beneficial effects that on the basis of electrospinning biological D printing, by means of the additional installation of a refrigeration platform, printing materials are made to be rapidly cooled and solidified in the platform, the printing object form structure is maintained, and the printing formability is greatly improved; and the biological electrospinning 3D printing device is convenient to operate, and the problem of the poor formability of biological three-dimensional printing materialsis solved.

Description

technical field [0001] The invention relates to the technical field of biological three-dimensional printing, in particular to a low-temperature forming bio-electrospinning 3D printing device and a preparation method thereof. Background technique [0002] Bio-3D printing technology is a kind of equipment that can position and assemble biological materials and even cells according to the principle of additive manufacturing under the drive of three-dimensional models, and can be used to manufacture medical devices, tissue engineering scaffolds and tissues and organs. Due to the limitation of the performance of biomaterials, the current bio-3D printing technology is based on melt extrusion or extrusion at room temperature. However, the printing accuracy of this kind of extrusion is poor, the diameter of the monofilament is large, and the porosity is low, so it is difficult to achieve good results. However, electrospinning has high printing precision, small filament diameter an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C64/20B29C64/10B33Y30/00B33Y10/00
CPCB29C64/20B29C64/10B33Y30/00B33Y10/00
Inventor 乔之光韩煜唐佳昕连梅菲孙彬彬姜闻博郝永强戴尅戎
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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