1114results about How to "Avoid infection" patented technology

The invention provides a nano enzyme as well as a preparation method and application thereof. The preparation method of the nano enzyme comprises the following steps: adding a stabilizer into a preheated solvent, and carrying out ultrasonic treatment; then adding ferric salt and cobalt salt, and adding alkali to adjust the pH value of the solution; then transferring the solution into a reaction kettle for reaction; and after the reaction, washing and separating to obtain the product. The obtained nano-enzyme is appropriate and uniform in particle size and good in dispersity, the enzyme activity is as high as 9.56 U / mg, and the application of the nano-enzyme in immunochromatography detection and plant canker prevention and treatment is widened. When the immunochromatography detection card prepared from the nano enzyme is used for detecting human hemoglobin, the detection limit can reach 0.05 ng / mL and is at least 10 times lower than that of a commercially available kit. When the nano-enzyme suspension is used for preventing and treating the kiwifruit canker, the nano-enzyme suspension with the concentration larger than or equal to 0.1 mg / mL is used, and the plant canker can be well controlled.

The invention belongs to the technical field of biology, and provides a porcine epidemic diarrhea virus mRNA vaccine and application. The mRNA molecule comprises a coding region for coding the S protein of the PEDV; the PEDV is of a G2a type, and two proline mutations I1076P and L1077P are introduced into an S protein. The invention further discloses a DNA molecule. An S protein of PEDV; a recombinant plasmid; recombining the host cell; an mRNA vaccine formulation which can be used to prepare an antibody against the S protein of PEDV after immunizing an animal; the invention further discloses application of the mRNA molecule, the DNA molecule, the recombinant plasmid or the host cell to preparation of a medicine for preventing PEDV (Porcine Epidemic Diarrhea Virus) infection. The vaccine prepared by the invention is fast in antibody generation and high in protection rate, can generate high-level neutralizing antibodies in serum and breast milk of sows after the pregnant sows are immunized before parturition, has a remarkable protection effect on piglets, and can effectively prevent the piglets from being infected with PEDV (Porcine Epidemic Diarrhea Virus).

The invention relates to lactobacillus crispatus LC30 for preventing and treating female genital tract infection and application of the lactobacillus crispatus LC30. The lactobacillus crispatus LC30 is preserved in the China General Microbiological Culture Collection Center with the preservation number of CGMCC NO.31923. The lactobacillus crispatus LC30 has good hydrogen peroxide production capacity and adhesion capacity, has a strong inhibition effect on main vaginitis pathogenic bacteria, and can be used for preventing and treating female genital tract infection. The composition is effective to nutritional pathogenic bacteria, and can also reduce form transformation and biological membrane formation of the pathogenic bacteria and prevent and treat drug resistance; besides, the fermentation product can reduce the content of pathogenic bacteria metabolites, regulate the secretion of cytokines and achieve the effect of relieving inflammation, so that the fermentation product can be used for preparing products for preventing and treating genital tract pathogenic bacteria infection, preventing and treating vaginitis and / or removing pudendum peculiar smell.

The invention relates to a mussel-like polylipoic acid-based hydrogel adhesive as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) uniformly mixing a sericin solution and a caffeic acid solution, then carrying out grafting reaction to obtain a reaction solution, and carrying out dialysis treatment and drying on the reaction solution to obtain sericin grafted caffeic acid; (2) adding lipoic acid into the lithium hydroxide solution, stirring until the lipoic acid is completely dissolved, then adding sericin grafted caffeic acid, and heating for reaction to obtain a PTALi-CAS mixture; and (3) cooling the PTALi-CAS mixture, so as to obtain the mussel-like polylipoic acid-based hydrogel adhesive. The dual-network PTALi-CAS hydrogel adhesive obtained in the invention realizes wet adhesion and rapid hemostasis, has excellent comprehensive performance, and is beneficial to providing a good repair environment for wounds as a wound dressing.

The invention discloses a leak-free core-shell hydrogel microsphere delivery system for non-contact flora transplantation as well as a construction method and application of the leak-free core-shell hydrogel microsphere delivery system. According to the invention, bacteria are encapsulated in a core of a core-shell microsphere through a two-step photo-initiation emulsion polymerization method of methacrylic acid gelatin, and a non-contact microbiota transplantation system (NMTS) is constructed. The NMTS can be used for biological encapsulation of various strains, shows encapsulation efficiency close to 100%, and has little influence on bacterial activity at the same time. NMTS demonstrates: a shielding effect that protects sealed bacteria from low pH values in the gastrointestinal tract and bile acid disruption; sufficient mechanical strength ensures that bacterial leakage is prevented and the infection risk is eliminated in the whole gastrointestinal tract delivery process; and internal and external substance exchange is realized, and the intestinal microorganism structure is remodeled. The invention provides a unique bacterial cell microencapsulation method which is a non-contact, safe and effective micropopulation transplantation method.

The invention belongs to the technical field of medical equipment, and particularly relates to a mask type vomit collecting device for the emergency department, the mask type vomit collecting device comprises a mask body, a mouth biting device is arranged on the inner side of the mask body, the mouth biting device comprises an arc-shaped flaring part and a circular tube part, an upper tooth groove and a lower tooth groove which are concave inwards are formed in the arc-shaped flaring part, and the circular tube part is communicated with the arc-shaped flaring part; the round pipe part is provided with a hard pipe section and a corrugated pipe section; the end, away from the arc-shaped flaring part, of the round pipe part is connected with a spitting pipe which penetrates through the mask body, the end, away from the mouth biting device, of the spitting pipe is connected with a conveying hose, and the end, away from the spitting pipe, of the conveying hose is connected with a collecting box. An elastic ring body is arranged on the edge of the mask body, two fixing bands are fixedly connected to the mask body, and the ends, away from the mask body, of the two fixing bands are detachably connected. By means of the device, vomitus of a patient can be conveyed into the collecting box in a closed mode, the vomitus cannot be exposed, and therefore people are prevented from feeling uncomfortable, and the vomitus pollution problem and the people infection problem are avoided.

The invention relates to a degradable surgical suture capable of self-constricting under the driving of near-infrared light and accelerating wound healing as well as a preparation method and application of the degradable surgical suture, and the degradable surgical suture capable of self-constricting under the driving of the near-infrared light is developed by virtue of a photo-thermal conversion effect of polydopamine on the basis of a thermal response characteristic of a shape memory material. And on the basis, a thermal control drug release system is endowed to the suture line to synergistically accelerate the wound healing process, and various suture problems confronted by the internal wound of the body are solved.

The invention belongs to the field of pesticide preparations, and particularly relates to 80% mancozeb wettable powder and application thereof, and the 80% mancozeb wettable powder comprises the following components in percentage by weight: 75-85% of mancozeb, 1-5% of a dispersing agent, 1-3% of a wetting agent, 2-4% of a synergistic auxiliary agent, 0.3-1% of a deflocculating agent and the balance of filler, the dispersing agent is TERSPERSE 2700, the wetting agent is Terweet-1004, the synergistic auxiliary agent is composed of tea saponin, PVP-K30 and nekal BX, the deflocculating agent is sodium hexametaphosphate, and the filler is kaolin. Wherein the mass ratio of the tea saponin to the PVP-K30 to the nekal BX is (1-4): (1-4): (1-4). The wettable powder prepared by the invention is relatively fine, relatively high in suspension rate, relatively good in spreadability, relatively strong in adsorption capacity and resistant to rain wash, and a layer of compact protective medicine film can be formed on the surfaces of crops after the wettable powder is applied to prevent infection of pathogenic bacteria, so that excellent disease prevention and treatment effects are achieved.

The invention provides a plasmodiophora brassicae effector Pb78, and the nucleotide sequence of the plasmodiophora brassicae effector Pb78 is shown The invention also provides an application of host-induced silencing of the plasmodiophora brassicae effector Pb78 in prevention and treatment of plasmodiophora brassicae infection, and also provides a plasmodiophora brassicae prevention and treatment liquid and a preparation method of the plasmodiophora brassicae prevention and treatment liquid. The invention verifies that host-induced plasmodiophora brassicae effector Pb78 silencing can effectively inhibit plasmodiophora brassicae infection and symptom formation of cruciferae plants. The preparation and the treatment method disclosed by the invention are suitable for various cruciferae crops and vegetables which can be infected by plasmodiophora brassicae, and are wider in applicability; the inhibition efficiency on clubroot is higher than that of medicament treatment, and the compound has the advantage of no pesticide residue and is high in safety; due to the adoption of a seed treatment mode, the method is particularly suitable for preventing and treating clubroot susceptible seedlings.

The invention provides hydrogel wound dressing and a preparation method thereof.The hydrogel wound dressing comprises a hydrogel layer, a supporting layer and a protective layer, the hydrogel layer is prepared from, by mass, 10%-15% of polyvinylpyrrolidone, 5%-8% of polycaprolactone, 2%-4% of sodium carboxymethyl cellulose, 1%-3% of chitosan, 0.5%-1.5% of an antibacterial agent, 0.1%-0.3% of an antioxidant and the balance water; the invention discloses a graphene quantum dot gel which comprises the following components in percentage by weight: 0.01-0.1% of a growth factor, 0.1-0.5% of a temperature-sensitive polymer, 0.05-0.15% of graphene quantum dots, 0.5-1.5% of a self-healing polymer, 0.5-1.5% of a pH sensitive material, 0.1-0.3% of nano titanium dioxide and the balance of deionized water. The supporting layer is a porous polylactic acid film, and the thickness of the supporting layer is 0.1-0.3 mm; the protective layer is an air-permeable polyurethane film, and the thickness of the protective layer is 0.2-0.4 mm. Through the synergistic effect of an antibacterial agent, nano titanium dioxide and graphene quantum dots, the antibacterial performance of the dressing is remarkably improved.

The invention belongs to the technical field of regenerated medical dressings, particularly relates to a plant polysaccharide hydrogel medical dressing for promoting tissue damage repair and application thereof, and provides the following scheme that a medical and mechanical combined product comprises a regenerated medical dressing and a low-temperature sterile storage box for storing the regenerated medical dressing, the regenerated medical dressing comprises a hydrogel main body, open pores formed in the hydrogel main body, sustained-release vesicles arranged in the open pores, and stem cells and a cell culture medium which are filled in the sustained-release vesicles. The stem cell hydrogel can rapidly break blood, rapidly stop bleeding by being attached to a wound surface and promote wound closing, stem cells are inoculated to the upper surface of the hydrogel formed by dendrobium polysaccharides, aloe, lily, coptis chinensis and honeysuckle, safe application of the stem cells is achieved, active factors secreted by the stem cells are slowly released to the skin wound surface, and the wound healing effect is achieved. Through contact stimulation between cells, various cytokines can be secreted better, and the skin repair efficiency is improved.

The invention relates to the technical field of medical rehabilitation devices, and provides a neck rehabilitation device after a neck operation, the neck rehabilitation device comprises a lower jaw supporting disc and a shoulder supporting disc, limiting discs are fixedly mounted on the sides, close to each other, of the lower jaw supporting disc and the shoulder supporting disc, and limiting insertion holes are uniformly formed in the sides, close to each other, of the limiting discs; adjusting and supporting mechanisms, photon treatment mechanisms and massage mechanisms are alternately arranged between the upper limiting disc and the lower limiting disc, the upper ends and the lower ends of the photon treatment mechanisms and the massage mechanisms are inserted into the limiting insertion holes, and the upper ends and the lower ends of the adjusting and supporting mechanisms are fixedly installed on the sides, close to each other, of the limiting discs. The neck of a patient can be comfortably supported and braked by adjusting the supporting mechanism, meanwhile, the vertical height can be adjusted to adapt to patients with different neck lengths, and the photon treatment function, namely red and blue light irradiation treatment, prevention of neck wound infection and promotion of early healing of a wound, of the neck of the patient is achieved through the photon treatment mechanism.

The invention discloses an MQDs-PEI-coated miR43-CMCS / TA composite nanomaterial for preventing and treating plant viruses as well as a preparation method and application of the MQDs-PEI-coated miR43-CMCS / TA composite nanomaterial, and belongs to the technical field of genetic engineering. The composite nano material is prepared from Mxene-QDs, polyetherimide, carboxymethyl chitosan, tannic acid and miR43 nano microspheres, the nano composite material is small in particle size and high in drug loading capacity, has an excellent protection effect and pH release capacity on miR43, can deliver miR43 into a plant body in a spraying mode and the like, and can be used for preparing the miR43 in the plant body by specifically shearing NbIAA29 in the plant. Therefore, replication and infection of the PVY virus and the TMV virus are inhibited, and important significance is achieved on prevention and treatment of the PVY virus and the TMV virus.

The invention discloses a cutting and shaping device for an acupoint pressure stimulation patch, and relates to the technical field of traditional Chinese medicine, the cutting and shaping device comprises a base, a moving plate is slidably connected with a third fixing plate through a sliding assembly, an annular cutter is fixedly mounted at the bottom of the moving plate, an elastic part is arranged in the annular cutter, and an intermittent rotating part is arranged on the base. A disinfection box is fixedly mounted on the surface of the moving plate, a transmission part is arranged on the disinfection box, the intermittent rotating part moves to drive the winding roller to intermittently rotate, the driving plate intermittently abuts against the sliding assembly to drive the moving plate and the annular cutter to intermittently and vertically slide on the three surfaces of the fixed plate in a reciprocating mode, continuous cutting is achieved, time is saved, and the cutting efficiency is improved. The cut acupuncture point pressure stimulation patch is pushed out of the annular cutter through the elastic component, bonding is avoided, the production efficiency is improved, and the disinfection effect is achieved by spraying disinfectant in the disinfection box to the inner wall of the annular cutter and the cut of the pressure stimulation patch through intermittent movement of the transmission component.

The invention provides antibacterial carboxymethyl cellulose hemostatic gauze and a preparation method thereof.The preparation method comprises the steps that carboxymethyl cellulose gauze is soaked in a PBS buffer solution, N-hydroxysuccinimide and 1-ethyl-(3-dimethylaminopropyl) carbodiimide are added into the PBS buffer solution, and a soaking solution is obtained after uniform mixing; adding the graft modified alginate oligosaccharide into the soaking solution, mixing and stirring to generate grafting reaction, taking out the carboxymethyl cellulose gauze after the reaction is finished, washing and drying to obtain the antibacterial carboxymethyl cellulose hemostatic gauze. According to the preparation method disclosed by the invention, the catechol-grafted modified alginate oligosaccharide and partially carboxymethylated carboxymethyl cellulose gauze are subjected to amidation grafting compounding, so that the hemostatic gauze with excellent antibacterial and hemostatic properties is prepared.

The invention discloses a low-smoke-density high-temperature-resistant halogen-free special flame-retardant optical cable, which comprises a cable core, an inner sheath and a fireproof layer from inside to outside, and is characterized in that the fireproof layer comprises a fireproof layer made of a ceramic silicone rubber material; the cable core comprises optical fibers, a loose tube, a reinforcing piece and an internal flame-retardant thermal insulation layer, the reinforcing piece is located in the center of the cable core, the optical fibers are arranged in the loose tube to form an optical fiber unit and surround the reinforcing piece, the internal flame-retardant thermal insulation layer comprises water-blocking yarn and a calcined mica tape, and the space between the optical fiber unit and the reinforcing piece is filled with the water-blocking yarn. And the optical fiber units, the reinforcers and the water-blocking yarns are wound by the calcined mica tape in a multi-layer and multi-pitch manner. According to the invention, the ceramic silicone rubber material is adopted and is ceramized in a flame state or at a high temperature of more than 500 DEG C to form an oxygen barrier layer, so that a flashover phenomenon in the cable is prevented; ointment is removed from the structure, and the water-blocking yarn and the calcined mica tape are used for blocking water, so that smoke in the combustion process is reduced, and the harm to personnel is less under the condition of fire hazard.

The invention discloses a preparation method and application of a response type NO release anticoagulant hydrogel material. The preparation method comprises the following steps: providing methylacryloylated recombinant collagen; providing methacrylated hyaluronic acid; providing caffeic acid arginine amide modified hyaluronic acid; the response type NO release anticoagulant hydrogel material is obtained by taking methylacryloylated recombinant collagen, methylacryloylated hyaluronic acid and caffeic acid arginine amide modified hyaluronic acid as raw materials. The prepared hydrogel material has the advantages of resisting bacteria, promoting proliferation of endothelial cells, inhibiting proliferation of smooth muscle cells, resisting inflammation, promoting angiogenesis, inhibiting thrombosis and the like, arginine can serve as an endogenous NO donor in blood to release NO molecules, and therefore the effect of promoting vascular endothelial repair is achieved, and the hydrogel material has the advantages of being capable of resisting bacteria, promoting proliferation of endothelial cells, inhibiting proliferation of smooth muscle cells, resisting inflammation, promoting angiogenesis, inhibiting thrombosis and the like. The introduced NO molecules enable the hydrogel material to have good anticoagulant performance, and the hydrogel material is expected to be used for preparing an artificial blood vessel anticoagulant coating.

The invention discloses a fish circRNA and application thereof, the fish is pelteobagrus fulvidraco, the circRNA is named circArid4b, and the nucleotide sequence of the circRNA is shown as SEQ ID NO.1. The invention further discloses a preparation method of the circRNA. The fish circRNA provided by the invention can regulate and control Arid4b expression of a source gene of the fish circRNA under hypoxia and bacterial infection conditions, influence apoptosis pathways and inflammatory reactions, and finally regulate and control antibacterial reactions. The invention further provides an interferent of the circRNA, the circRNA interferent can be used as a fish immunomodulator, infection of Aeromonas veronii on pelteobagrus fulvidraco under the low-oxygen condition is remarkably inhibited, and a new mode is provided for efficiently improving the antibacterial immunity of fish under the low-oxygen environment.

The invention provides a tightening and repairing gynecological gel. Preparation raw materials comprise carbomer, sodium hyaluronate, an animal umbilical cord extract, madecassoside, carnosine, a polygonum cuspidatum root extract, a scutellaria baicalensis root extract, a tea leaf extract, a chamomile flower extract, elastic collagen, arginine, pentanediol, butanediol, glycerin, p-hydroxyacetophenone, capryloyl hydroximic acid and purified water. The gynecological gel can maintain balanced strains, so that the microenvironment of the vagina is kept normal; vaginal atrophy is improved, the tight state of the vagina is recovered, and vaginal dryness is relieved; damaged mucosa can be repaired, the natural defense function of women is enhanced, and gynecological infection is prevented. The gynecological gel has good biocompatibility, cell affinity and mechanical properties, and can supplement collagen to female private parts, repair damaged vaginal mucosa and promote wound healing; the vagina can be moisturized and moistened, the looseness and dryness of the vagina are improved, the micro-ecological balance of the vagina is adjusted, and the immunity of a female reproductive system is improved.

The invention discloses application of sclareol in preparation of drugs for resisting porcine reproductive and respiratory syndrome virus, and belongs to the field of veterinary drugs. According to the invention, Marc-145 cells are taken as host cells, a plurality of porcine reproductive and respiratory syndrome virus strains are selected for infection, and the antiviral performance of sclareol is tested; experimental results show that 30-50 [mu] M sclareol has no obvious toxicity to host cells, and can significantly inhibit infection of different porcine reproductive and respiratory syndrome virus strains in the host cells. The sclareol has good activity of resisting porcine reproductive and respiratory syndrome virus infection, and the sclareol is a medicine with a natural source, has the advantages of safety, few side effects, low metabolic residue and no pollution, and provides a reliable basis for treatment, prevention and control of porcine reproductive and respiratory syndrome.

The invention provides an antifouling developing coating material and a preparation method and application thereof.The antifouling developing coating material is of a structure shown in the formula I. The antifouling developing coating material combines antifouling and developing through a covalent binding technology, has excellent antifouling performance and developing performance, and can be applied to the field of chemical engineering. According to the invention, the stability and durability of the developing effect can be ensured, the safety is good, the application range is wider, and powerful support is provided for the safety of medical equipment and the accuracy of medical images.

The invention provides a crayfish egg in-vitro hatching device and hatching method, and relates to the technical field of in-vitro hatching. The in-vitro hatching device for the crawfish eggs comprises a hatching barrel, wherein a plurality of overflow ports are formed in the side wall of the hatching barrel; an egg containing barrel is embedded in the hatching barrel, the top end of the egg containing barrel is rotationally connected with an upper cover plate, and an aeration pipe is connected to the upper cover plate in an inserted mode and extends to the inner bottom of the egg containing barrel; the outer wall of the hatching barrel is sleeved with an overflow barrel, the aeration pipe is rotationally communicated with a first power mechanism, the first power mechanism is coaxially and rotationally embedded in the egg containing barrel, air is continuously injected to drive water to roll on the inner side and the outer side of the egg containing barrel, and active eggs and inactive eggs are gradually separated; the screening holes are utilized to gradually separate inactive eggs from active eggs, and the eggs overflow into the overflow cylinder from the overflow port under the rolling action of the water body, so that good eggs and bad eggs are separated, and bacteria on the bad eggs are prevented from quickly infecting the good eggs.

The invention discloses a suture removing auxiliary device for cardiac surgery, and belongs to the technical field of surgical suture removing, the suture removing auxiliary device comprises a fixing device, a suture cutting device and a suture pulling device are arranged on the fixing device, the suture cutting device is used for cutting a suture on the skin, and the suture pulling device is used for pulling the cut suture out of the skin. The fixing device is used for adjusting the positions of the thread trimming device and the thread pulling device; the fixing device can adjust the positions of the thread trimming device and the thread pulling device in the X direction, the Y direction and the Z direction, the thread trimming device and the thread pulling device can reach the surgical site where a thread needs to be removed, and the fixing base is installed on a sickbed and is convenient to use. When the thread cutting device moves, the movable knife and the fixed knife are continuously opened and closed to cut off the surgical thread on the skin, the thread pulling claw is driven to continuously pull out the cut surgical thread when the thread cutting device moves, the whole action is conducted continuously, the automation degree is high, and continuity is good.

The utility model discloses a test tube for sampling, which relates to the technical field of sampling, and comprises a test tube main body and a cover cap, the outer surface of the test tube main body is provided with an anti-slip sleeve, the anti-slip sleeve is internally provided with an anti-falling component, the anti-falling component comprises a support rod, the support rod is positioned in a groove of the anti-slip sleeve, and the cover cap is arranged on the support rod. The top of the support is provided with a take-up and pay-off barrel, one end of the take-up and pay-off barrel is provided with a hexagonal rod, a rope is installed in the take-up and pay-off barrel in a surrounding mode, one end of the take-up and pay-off barrel is provided with a movable groove, a lead screw is installed in the movable groove, and one end of the lead screw is provided with a driving motor. The anti-falling assembly is installed, the cap and the anti-skid sleeve are connected and fixed through the rope in the winding and unwinding barrel inside the anti-skid sleeve, and the length of the winding and unwinding rope of the winding and unwinding barrel is conveniently controlled while the movable protruding block is driven by the lead screw to move; and the rope is convenient to take and can prevent the cap from being lost and being stained with dust and bacteria when being placed on the ground.

The invention belongs to the field of biology, and discloses a foot-and-mouth disease virus O-type inner broad-spectrum neutralizing swine monoclonal antibody and application thereof, the amino acid sequence of a heavy chain variable region of the monoclonal antibody is shown as SEQ ID NO.1, the amino acid sequence of a light chain variable region of the monoclonal antibody is shown as SEQ ID NO.2, the antigen key amino acid residue recognized by the monoclonal antibody is VP2 protein 77 site, and the amino acid sequence of the heavy chain variable region of the monoclonal antibody is shown as SEQ ID NO.1. The amino acid sequence of the light chain variable region of the monoclonal antibody is shown as SEQ ID NO.2. The site is located at a structural protein VP2B-C ring, is a conformational epitope, does not react with an A-type antigen, is an intra-strain broad-spectrum neutralizing antibody, and shows relatively strong neutralizing efficacy (IC50 is less than 5 [mu] g.mL <-1 >). Meanwhile, the invention also provides application of the monoclonal antibody.

The invention discloses a composition for resisting porcine viral diarrhea and application of the composition. The composition for resisting porcine viral diarrhea is prepared from the following components in parts by mass: 2 parts of phloretin, 1 part of N-acetyl-D-galactosamine and 100 parts of proline. The composition can further comprise one or more auxiliary materials of absolute ethyl alcohol, propylene glycol, dimethyl sulfoxide, edible oil, water, tween-80, lactose, defatted rice bran, corncob powder, soluble starch, bran, silicon dioxide, montmorillonite, vermiculite, medical stone, zeolite powder, white carbon black and the like. The composition can significantly inhibit the proliferation of PEDV, TGEV and PoRV, and inhibit the infection of PEDV, TGEV and PoRV on cells, and further, the composition can be used for preparing drugs or feed additives for resisting porcine diarrhea diseases caused by viruses such as PEDV, TGEV and PoRV.

The invention discloses a nanometer material-based postoperative wound intelligent healing patch preparation method, which comprises: S1, preparing a temperature response layer, and compounding PNIPAM with surface-modified zinc oxide nanoparticles; s2, preparing a pH response layer, and compounding chitosan with the surface modified titanium dioxide nanoparticles; s3, a humidity response layer is prepared, and release of silver ions is optimized by adopting a PEGDA and silver nanoparticle composite material; s4, assembling the layers layer by layer through an electrostatic spinning technology or a lamination technology, and controlling process parameters in combination with meta learning and transfer learning to complete preparation of an overall structure of the patch; s5, embedding temperature, pH and humidity sensors, and constructing a sensor data set; s6, the drug release rate and the material phase change behavior are dynamically adjusted, and accurate response is achieved; and S7, after patch preparation is completed, combining Bayes and a multi-objective evolutionary algorithm to optimize sterilization parameters. The intelligent healing patch is prepared by combining a nano material with an intelligent algorithm, and real-time environmental response is realized.

The invention relates to the technical field of nutritional supplements, and discloses a pet nutritional supplement capable of improving immunity, which is prepared from the following raw materials in parts by weight: 35 to 45 parts of taurine, 5 to 8 parts of natural lutein, 10 to 30 parts of chondroitin sulfate, 10 to 20 parts of water, 20 to 30 parts of corn starch, 10 to 20 parts of semen plantaginis and 30 to 50 parts of microbial fermentation products. The 35-45 parts of taurine and the 10-30 parts of chondroitin sulfate can be selected from one or more of sardine powder, black and white fish powder, beef powder, pig powder, chicken powder and the like. According to the pet nutritional supplement capable of improving immunity and the preparation method thereof, the semen plantaginis is added into the raw materials, so that the pet kidney can be promoted to generate more urine, urethra flushing is facilitated, bacterium breeding is reduced, and urinary system infection is prevented, and the taurine is added, so that heart condition improvement, brain development promotion and retina protection are facilitated. When the pet supplement is prepared, the pet supplement is prepared by using a freeze-drying machine, so that the loss of nutrient substances is reduced.

The present invention belongs to the field of C08G technology, and more specifically relates to a thermoplastic polyurethane elastomer for antibacterial air cushions, and a preparation method and application thereof. A thermoplastic polyurethane elastomer for antibacterial air cushions, the raw materials for preparing the thermoplastic polyurethane elastomer include, by weight percentage: 50-60% polyester polyol, 30-40% isocyanate, 5-10% chain extender, and the remainder of the auxiliary agent is supplemented to 100%. The antibacterial rate of the thermoplastic polyurethane elastomer prepared by the present invention can be as high as 99% or more. When it is used in the shoe material air cushion, it can avoid the infection of bacteria and the like caused by the foot movement, sweating, etc. during use; the thermoplastic polyurethane elastomer prepared by the present invention has good processing performance, and has good tear strength and tensile properties. When it is used in the field of air cushions, it can avoid the damage of the finished product caused by external forces such as tearing and stretching, and improve its service life and use value in the field of shoe material air cushions.

The utility model discloses a dialysis catheter connector with a protective sleeve, relates to the technical field of peritoneal dialysis, and solves the problems that in the prior art, a dialysis catheter connector is bound by gauze and is fixed by adhesive tape, so that the dialysis catheter connector is easy to slip, and the operation process is complicated, time-consuming and labor-consuming. The protective sleeve comprises a connector body and a protective sleeve body, the connector body comprises an indwelling tube end connector and an external tube end connector, the end of the indwelling tube end connector and the end of the external tube end connector are communicated with an indwelling catheter and an external catheter respectively, the indwelling tube end connector is detachably connected with the external tube end connector, and the protective sleeve body comprises a silicon rubber sleeve. The silica gel sleeve is arranged on the indwelling tube end connector in a sleeved mode, the end, away from the external tube end connector, of the silica gel sleeve is connected with the indwelling tube end connector in a sealed mode, and the other end of the silica gel sleeve is connected with a sealing assembly, detachably connected with the external tube end connector through the sealing assembly and tightened in a sealed mode. The sealing device is simple to operate, convenient to use, good in sealing performance, stable in connection and beneficial to use.