39 results about "Internal wounds" patented technology

Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.

A surgical fastening system, utilizing surgical clips made from bio-absorbable materials, for use in the rapid closing of deep internal wounds in humans or animals is disclosed. Elements of the system include surgical clips, applicators of surgical clips and dispensers of surgical clips. The surgical clips may contain small amounts of prophylactic antibiotic medication, long-acting time-release pain medication, radio-opaque markers, small amounts of radioactive material, colors, and/or patterns.

The present invention relates to findings that reducing the activity of Plasminogen Activator Inhibitor-1 (PAI-1) suppresses an excessive deposition of collagen which is known as a cause for the formation of abnormal scars. These abnormal scars include but are not limited to keloids, adhesions, hypertrophic scars, skin disfiguring conditions, fibrosis, fibrocystic conditions, contractures, and scleroderma, all of which are associated with or caused by an excessive deposit of collagen in a wound healing process. Accordingly, aspects of the present invention are directed to the reduction of PAI-1 activity to decrease an excessive accumulation of collagen, prevent the formation of an abnormal scar, and/or treat abnormal scars that result from an excessive accumulation of collagen. The PAI-1 activity can be reduced by PAI-1 inhibitors which include but are not limited to PAI-1 neutralizing antibodies, diketopiperazine based compounds, tetramic acid based compounds, hydroxyquinolinone based compounds, Enalapril, Eprosartan, Troglitazone, Vitamin C, Vitamin E, Mifepristone (RU486), and Spironolactone to name a few. Another aspect of the present invention is directed to methods of measuring PAI-1 activity in a wound healing process and determining the propensity of the formation of an abnormal scar.

Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.

Devices and methods are disclosed for delivering sealing compound to a wound in animals, including humans. Such wound sealing is important after deep skin penetrating lacerations or subsequent to internal wounds. The apparatus utilize an aerosol dispensing system that both mixes and applies a multi-part sealant compound. The aerosol system includes a plurality of sealant component chambers, a source of pressurized gas, an aerosol mixing head, a pressure regulator, a pneumatic switch, and a component pumping mechanism. The aerosol system, either a reusable or a disposable device, is further provided with a system that keeps dry components from liquid components and then automatically mixes the liquid and dry components prior to application. The system provides for easy control over the application, inexpensive manufacture, and simplified preparation, thus minimizing the time needed for application and enhancing the potential outcomes of the patient.

A dressing delivery system comprises an applicator for holding and positioning a wound dressing. The applicator comprises a sleeve having a distal spreading portion. The wound dressing is disposed on or adjacent the spreading portion. The applicator urges the dressing into contact with the wound. The sleeve is advanced to actuate the spreading portion, which increases the diameter of the applicator and preferably deploys the dressing.

Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.

A radiographic composition for promoting the formation of clots in blood includes a zeolite and iodine. A device for promoting the clotting of blood at an internal wound site includes a catheter; a delivery instrument insertable through the catheter; a radioopaque blood clotting agent that deliverable through the delivery instrument; and a positive pressure apparatus that can dispense the blood clotting agent to the wound site through the delivery instrument. A system for radiographically imaging an internally bleeding wound includes means for delivering a radioopaque blood clotting agent and means for radiographically imaging the radioopaque blood clotting agent. A method of imaging an internally bleeding wound includes the steps of inserting a catheter into a patient; advancing the catheter to a point adjacent the bleeding wound; depositing a radioopaque zeolite at the bleeding wound; and imaging the radioopaque zeolite to monitor blood-clotting caused by the zeolite.

The invention provides a method for preparing injectable microgelparticles, and the method comprises the following steps: adopting hyaluronic acid dry powder in accordance with standard requirements, carrying out cross-linking reaction to form water-insoluble cross-linking hyaluronic acid gel, carrying out postprocessing of dynamic dialysis, rotary crushing and centrifugal separation to form injectable microgelparticles. The method is safe and effective, and simple in processing flow, and can be used for adjusting the particle size of the microgelparticles by virtue of control on process parameters. The method has the advantages of good biocompatibility, internal anti-degradation capability, and suitability for subcutaneous filling, substituation of articular cavity lubricating fluid, conglutination prevention of internal wound and the like.

A tissue adhesive including cyanoacrylate and polyethylene glycol (PEG), wherein the PEG remains a polyether and wherein the tissue adhesive is bioabsorbable. A tissue adhesive including cyanoacrylate bulk monomer and cyanoacrylate nanoparticles containing a therapeutic therein. A kit for applying a tissue adhesive, including the tissue adhesive described above and an applicator. Methods of accelerating degradation of a cyanoacrylate tissue adhesive applying a tissue adhesive, closing an internal wound, administering a therapeutic to tissue, treating cancer, and preventing infection in a wound. Methods of method of making a bioabsorbable tissue adhesive and making a therapeutic tissue adhesive.

An apparatus for manufacturing an internal wound stator includes a winding arbor configured to receive a conductive wire. The apparatus also has a stator loader with a stator having a generally cylindrical shape with an interior opening and having a plurality of axial slots formed therein. The interior dimension of the stator is larger than the exterior dimension of the winding arbor such that the winding arbor and stator may traverse with respect to one another. The apparatus also has a first movable member configured for moving at least one of the winding arbor and the stator. The apparatus also has a second rotating member configured to rotate at least one of the stator and the winding arbor. The conductive wire is introduced through an interior of the winding arbor. The first movable member is configured to move at least one of the winding arbor and the stator relative to one another to wind the conductive wire in a first longitudinal manner and into a first of the plurality of axial slots. The second rotating member is configured to rotate at least one of the first winding arbor or the stator relative to one another to align the wire relative to a second axial slot of the plurality of axial slots. The first movable member is configured to move at least one of the winding arbor and the stator relative to one another to wind the conductive wire in a second opposite longitudinal manner and into the second axial slot.

The invention relates to a disposable hemostatic dressing wound leading-in first-aid hemostasis instrument, and belongs to the field of medical apparatuses and instruments. The instrument comprises a hemostatic material loading component and a pushing component. The hemostatic material loading component is used for storing compression-pill-shaped or flake chitosan hemostatic materials, and the front end is packaged through waterproof and breathable silica gel materials; and the pushing component is used for rapidly pressing the hemostatic materials into a wound. The disposable hemostatic dressing wound leading-in first-aid hemostasis instrument is particularly rapid and reliable in hemostatic effect on firearm wounds, penetration wounds and deep pricking wounds which are smaller in body surface penetration wound, large in internal wound and large in bleeding amount in battlefield rescuing. The disposable hemostatic dressing wound leading-in first-aid hemostasis instrument has the advantages that the efficient hemostatic materials are led into the deep wounds; as for tissue deep bleeding parts where bleeding stopping through a tourniquet or pressing is not suitable, the device can achieve the effects of accurate positioning, rapid bleeding stopping and hemorrhagic shock and dead preventing. When traumas accidentally occur, self rescuing or other rescuing can be carried out, and the valuable rescuing time can be won. The device has the advantages of being efficient in bleeding stopping, easy and convenient to operate, low in cost, convenient to carry, long in storage time and convenient to use.

The invention relates to a liquid injection process for a high-specific-energy lithium ion battery; the high-specific-energy lithium ion battery comprises a shell with an injection hole and an internal wound core; the process comprises the steps of (1) performing pulse impacting on the injection hole by using high-pressure gas; (2) evacuating; (3) injecting electrolyte into the lithium ion battery; (4) allowing the lithium ion battery to stand; the high-pressure gas is nitrogen 0.5-0.8 MPa, and pulse impacting is performed 3-10 times for 0.3-1 S. Pulse impacting is performed on the injection hole by using high-pressure nitrogen so that electrostatic adsorption among a positive plate, a diaphragm and a negative plate is opened, evacuating, injection and standing are carried out, electrolyte may permeate to the middle of the wound core smoothly, liquid injection is increased for the battery, electrolyte permeating time is shortened, and battery properties are improved. The injection time herein is at least 30% shorter than that of common processes, and the process of the invention is high in efficiency, low in cost, widely applicable and high in practicality.

The invention relates to an absorbable growth factor composite dressing which is mainly prepared from compound cellulose and growth factors, wherein the compound cellulose is prepared by compounding modified hydroxyethylcellulose and sodium alga acid. The dressing is prepared by compounding the modified hydroxyethylcellulose and the sodium alga acid to prepare the compound cellulose and then adding 0.02-0.05% of freeze-dried growth factor powder, and evenly mixing the compound cellulose with the powder. The dressing can promote rapid wound healing, shorten the treatment period and can be widely applied to various wounds comprising internal wounds and external wounds.

A negative pressure therapy unit is disclosed that is designed for healing internal wounds under the application of negative pressure. A plurality of tubes sequentially movable relative to one another are used to locate a filler material inside the organ. The tubes cover the filler material to avoid contact with the organ and filler material. A pressure tube passes internally to the plurality of tubes and communicates with the filler material. The filler material is in a compressed state between at least one of the plurality of tubes and the pressure tube. Translation of one of the plurality of tubes selectively exposes the filler material and permits the filler material to expand into the wound. The filler material is interchangeable on the wound and selectively on the pressure tube.

The invention discloses a dual-network adhesive for crosslinking of transglutaminase and a preparation method of the dual-network adhesive. The preparation method comprises the following steps: simplytreating gelatin, mixing the gelatin with glucan aldehyde, and performing crosslinking under physiological conditions through the promotion action of the transglutaminase to form the dual-network adhesive. According to the double-network characteristic, the strength of the adhesive body is enhanced, and the adhesion performance of the adhesive is improved through introduction of the glucan aldehyde. The preparation method has the characteristics of simple raw material synthesis, injectable adhesive and easiness in application. By utilizing the characteristics, the dual-network adhesive can beused as a surgical sealant, a medical adhesive and the like to be clinically applied, and has a good application prospect in the fields of human body internal wound repair and the like.

The invention discloses a cooking method for a confinement chicken soup. A fresh chicken soup is prepared through a plurality of processes by using confinement chicken, herba houttuyniae, red dates, longan and a plurality of condiments. The chicken soup cooked by the method is helpful for a puerperant to dispel exogenous evil and enhance health after delivery. Herba houttuyniae in auxiliary materials can dispel exogenous evil invaded in a human body, can resist virus and infection, and has an anti-inflammation effect. The puerperant is not liable to suffer mammitis after taking herba houttuyniae; and herba houttuyniae can accelerate heal of internal wounds produced in a delivery process.

The invention provides a disposal visible catheter. The catheter comprises a catheter body, a catheter head and a connecting part; the catheter body is located at one end of the connecting part, the appearance of the catheter body is conical, the catheter body is made from a silica gel transparent material, and the catheter body is fixedly connected with the connecting part; the catheter head is located at one end of the catheter body, made from a plastic material and fixedly connected with the catheter body; the connecting part is located at one end of the catheter body, connected with laparoscope equipment and used for guiding in a medical instrument. The invention provides a disposal visible catheter, the transparency of the catheter head is improved through the transparent silica gel material, the appearance of the catheter body is arranged as a composite medical dissection conical shape, so that the catheter is conveniently inserted into a human body, internal wounds are conveniently cleaned through a water outlet formed in the edge side and a water inlet formed in the main position to help observation and medical surgical operation, the plastic material is adopted by the catheter body, the catheter body can be directly discarded and replaced after being used, the cost is low, and crossed infection caused by repeated use is prevented.

A disposable mammary gland biopsy needle machining and assembling process disclosed in the invention comprises the following steps: S1, an outer knife pipe with a lateral negative pressure hole is prepared and machined, and the proper pipe length is cut; S2, after cutting is completed, a pipe sampling hole is cut through laser, and the lateral negative pressure hole is punched through laser; S3, an acid solvent is adopted for cleaning the punched pipe to remove burrs; S4, while steps S1 to S3 are carried out, an outer cutter pipe lateral negative pressure channel pipe is prepared, the proper pipe length is cut, the pipe is sliced, and burrs are removed; S5, the two pipes are subjected to laser welding forming, and ultrasonic welding is conducted after assembling; S6, injection molding of apuncture blade coupler B and injection molding of a puncture blade coupler A are carried out; and S7, edge grinding and stamping procedures are conducted, and then the blade is punctured to completethe assembly process. The biopsy needle has a puncture sensing function, the uniformity of cutting force is guaranteed to the maximum extent while cutting is conducted, the internal wound surface is prevented from being too large, then biopsy samples are uniform in size, and pathological analysis is facilitated.