1246 results about "Dialysis" patented technology

The invention belongs to the technical field of medical cosmetology and plastic surgery, and particularly relates to a hydroxyapatite microsphere facial skin filling agent for injection and a preparation method thereof. Hydroxyapatite microspheres and sodium hyaluronate are uniformly mixed, a cross-linking agent is added, and cross-linked sodium hyaluronate-hydroxyapatite core-shell structure microsphere particles which take hydroxyapatite microspheres as cores and cross-linked sodium hyaluronate as shells and are of a soft-in-hard structure can be obtained through dialysis and particle grading. The cross-linked sodium hyaluronate is used as a core-shell structure, so that the hydroxyapatite is locked in the cross-linked sodium hyaluronate, agglomeration is effectively avoided, the extrusion resistance can be well reduced by the soft-wrapped-hard core-shell structure, and the propulsive force is smaller. All the components in the hydroxyapatite microsphere facial skin filler for injection have better biocompatibility, so that the rejection of the filler in a body is reduced, and the skin problems of allergy, redness, swelling, small lumps and the like after injection and filling are effectively avoided.

The invention discloses a medicine dialysis dry powder production whole process intelligent supervision method, and belongs to the technical field of medicine production intelligent monitoring. The method comprises the following steps: collecting a raw material purity parameter, a mixing process microscopic parameter and a finished product performance index parameter in real time through a sensor array module; the data processing module performs preprocessing and feature extraction on the collected parameters; the deep learning model module carries out training based on the preprocessed parameters to generate a dynamic ratio adjustment scheme; the control module controls the raw material conveying amount of the production equipment according to the adjustment scheme; and the closed loop feedback module feeds back the adjusted finished product performance index parameters to the deep learning model module to form a dynamic optimization closed loop. The method further comprises an abnormity early warning step and a model iteration step, the whole-process intelligent supervision of the medicine dialysis dry powder production process is realized, the proportion can be automatically adjusted according to the purity fluctuation of the raw materials, the stable product quality is ensured, the production efficiency is improved, and the manual intervention requirement is reduced.

The invention discloses a hemodialysis patient home management system based on an informatization technology, and relates to the technical field of medical informatization, and the system comprises the following components: a data collection and analysis module which collects the information of vital signs, dialysis data, diet intake and living habits of a patient in real time through a wearable device and an intelligent home sensor, according to the method, a decision tree algorithm is utilized to predict dialysis requirements and complication risks, a linear regression model is combined to predict dialysis effects, scientificity and effectiveness of a dialysis scheme are effectively improved, a Q-learning algorithm is introduced to dynamically adjust the dialysis scheme, and the dialysis efficiency is improved. The treatment strategy is continuously optimized according to the real-time feedback of the patient, the comfort of the patient is improved, the long-term effect of dialysis treatment is remarkably improved, the workload of medical staff is relieved, and the self-management ability of the patient is enhanced.

The invention discloses a corn peptide for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof, and belongs to the technical field of biological peptide extraction. The preparation method comprises the following steps: crushing and sieving corn, dissolving the corn in deionized water, adjusting the pH value to be alkaline, and performing ultrasonic-assisted extraction to obtain corn homogenate; centrifuging, taking supernate, adjusting the pH to be neutral, centrifuging, adding an ethanol solution with the mass fraction of 10%, standing, carrying out continuous flow centrifugation, suspending precipitates in distilled water, dialyzing in a dialysis bag, and freeze-drying to obtain crude corn protein; the preparation method comprises the following steps: preparing an aqueous solution, carrying out variable-temperature treatment, adjusting the pH value to be alkaline, adding trypsin and alkaline protease, carrying out enzymolysis, repeating the enzymolysis twice, and after the enzymolysis is finished, carrying out heating enzyme deactivation, centrifugation, sediment discarding, ultrafiltration, centrifugation, supernatant taking and spray drying to obtain the corn peptide. The corn peptide can remarkably shorten the drunkenness time and sobering time of mice and reduce the drunkenness duration, and has good effects of dispelling the effects of alcohol and protecting the liver.

The invention relates to a preparation method of a microwave-assisted synthesized near-infrared electrochemical luminescence gold nanocluster and application of the gold nanocluster in miRNA (micro Ribonucleic Acid) detection. The preparation method comprises the following steps: under a stirring condition, adding a gold source and alkali into a Met solution to obtain a mixed solution, carrying out microwave irradiation reaction, and carrying out solid-liquid separation to obtain a Met-Au NCs solution; the preparation method comprises the following steps: activating a Met-Au NCs solution by using EDC and NHS, adding a DNA solution, mixing, and dialyzing to obtain a Met-Au NCs-DNA compound, namely the near-infrared electrochemical luminescence gold nanocluster. Compared with Au NCs prepared by a common mild method, the Met-stable Au NCs prepared by a microwave-assisted method has the advantage that the fluorescence and electrochemical luminescence efficiency at 835 nm is improved. The invention also provides a'signal closing 'ECL (electron cyclotron ligand) biosensor for high-sensitivity detection of the miRNA-107 (MicroRNA-107), and a method for detecting the miRNA-107 (MicroRNA-107). The sensor is simple to operate and good in repeatability, and has important scientific significance and application value for clinical early diagnosis of cancers.

The invention discloses a digital full-period monitoring and evaluating system for the internal fistula function of a uremia patient, and relates to the technical field of medical monitoring. By integrating a multi-mode sensor, intelligent data processing and cloud analysis technologies, comprehensive, accurate and real-time monitoring of the internal fistula function is realized. The system comprises a data acquisition unit, a data transmission unit, an intelligent processing terminal, a cloud server, a user interaction unit and a distributed storage unit, and can measure multi-dimensional physiological parameters such as blood flow velocity, blood flow volume and blood flow pressure and obtain the endovascular microstructure and elastic characteristics. And the cloud server executes multi-modal data fusion analysis, generates an early warning signal, and triggers alarms of different levels through a hierarchical early warning strategy. According to the system, the precision and comprehensiveness of internal fistula function monitoring are improved, the complication risk is reduced, and powerful technical support is provided for dialysis treatment of uremia patients.

The utility model discloses a heat dissipation system and a metal heat dissipation disc used for an auxiliary dialysis phototherapy device, the auxiliary dialysis phototherapy device comprises a base, a phototherapy lamp set and an operation panel, the heat dissipation system comprises the metal heat dissipation disc and a heat dissipation device, the metal heat dissipation disc comprises a heat dissipation disc main body and a heat dissipation disc outer ring, and the heat dissipation disc main body and the heat dissipation disc outer ring are arranged on the base. The heat dissipation disc body is arranged in the heat dissipation disc outer ring and integrally formed with the heat dissipation disc outer ring, a round lamp strip groove is formed in the front face of the heat dissipation disc body, a middle fin structure is arranged at the position, at the lamp strip groove, of the back face of the heat dissipation disc body, and the heat dissipation disc body is arranged above the base through the heat dissipation disc bracket. The operation panel is installed above the heat dissipation disc body, the heat dissipation disc outer ring protrudes out of the edges of the heat dissipation disc bracket and the operation panel, and an outer edge fin structure is arranged on the back face of the heat dissipation disc outer ring. The auxiliary dialysis phototherapy device can be greatly cooled, the temperature of blood in the dialysis tube is prevented from rising, and the dialysis treatment effect is enhanced.

The invention provides a composite film based on a two-dimensional covalent organic framework as well as a preparation method and application of the composite film. The preparation method comprises the following steps: pouring a 2, 4, 6-triformyl phloroglucinol solution into the bottom layer of a container, slowly dropwise adding deionized water as a buffer solution, and dropwise adding a diamine monomer 2, 5-diaminobenzene sulfonic acid solution on the uppermost layer; under a static condition, carrying out a synthetic reaction at room temperature; after the reaction is finished, sucking out the upper-layer nanosheet by using a suction tube, and filling the upper-layer nanosheet into a treated dialysis bag; the synthesized nanosheet is subjected to dialysis treatment in deionized water, a TpPa-SO3H nanosheet is obtained, and a covalent organic framework nanosheet solution is obtained; taking a carbon nanotube, adding an organic solvent, and carrying out ultrasonic dissolution to obtain a carbon nanotube solution; a carbon nanotube solution and a covalent organic framework nanosheet solution are taken to be mixed and subjected to uniform ultrasonic treatment, the mixture is assembled to a nylon membrane through vacuum pressurization, drying is conducted, and the two-dimensional covalent organic framework composite membrane is obtained and has good performance and can be well applied to seawater desalination or dye separation.

The invention discloses chiral ionizable lipid nanoparticles and a preparation method thereof, and belongs to the technical field of biomedical materials. The chiral ionizable lipid nanoparticle comprises chiral amino acid derived lipid, ionizable lipid, auxiliary lipid, cholesterol, a phospholipid polyethylene glycol derivative and an RNA (Ribonucleic Acid) drug, the preparation method comprises the following steps: dissolving chiral amino acid derived lipid in methanol, respectively dissolving ionizable lipid, auxiliary lipid, cholesterol and phospholipid polyethylene glycol derivative in ethanol, and mixing to obtain a total lipid organic phase; dissolving an RNA drug in DEPC water to obtain an RNA aqueous solution, and mixing the RNA aqueous solution with an acidic buffer solution to obtain an RNA aqueous phase; quickly mixing the total lipid organic phase and the RNA water phase, and standing and incubating; adding the mixed solution into a 3500 Da dialysis bag, taking 1 * phosphate buffer solution (PBS, pH = 7.4) as an external water phase, and dialyzing to obtain the chiral ionizable lipid nanoparticles. The lipid nanoparticles provided by the invention can enhance the RNA uptake efficiency, and have good application prospects in the treatment of systemic inflammation and other diseases.

The invention provides a hemodialysis room whole-process information management system based on active learning, and relates to the technical field of data processing, and the system comprises a feature construction module which is used for carrying out the structural processing of original dialysis information data, and extracting a plurality of feature factors related to the current physical state of a patient; the risk identification module is used for constructing a training sample group, performing supervised training by introducing a label, and generating a risk judgment model; the early warning generation module is used for generating a risk probability result and generating early warning information associated with the current patient identifier when the risk probability result reaches a preset risk threshold value; the scheduling module is used for dynamically adjusting the treatment scheduling sequence of the current patient according to the early warning information and recording the actual intervention effect after the treatment scheduling sequence is adjusted; the feedback learning module is used for endowing each feature factor with a weight value according to an actual intervention feedback result and feeding back the weight value to the risk identification module; according to the invention, autonomy and accuracy of information management are improved.

The invention discloses an EGCG-Cu complex, an EGCG-Cu-Cs nanoparticle, a preparation method of the EGCG-Cu complex, and an application of the EGCG-Cu-Cs nanoparticle. The preparation method comprises the following steps: mixing an aqueous solution of EGCG and an aqueous solution containing copper ions, adjusting the pH value, stirring for reaction, dialyzing or centrifuging, and freeze-drying to obtain the EGCG-Cu complex; the EGCG-Cu complex is dissolved in water, a chitosan solution is added, stirring reaction, centrifugal washing and freeze drying are carried out, and the EGCG-Cu-Cs nanoparticles are obtained. The EGCG-Cu complex and the EGCG-Cu-Cs nanoparticles prepared by the invention are uniform in size and good in dispersity, and have excellent xanthine oxidase inhibition effect and free radical scavenging effect.

The present disclosure pertains to a media supply arrangement for supplying a medical treatment device with a medium, in particular for supplying an extracorporeal blood treatment device with a dialysis medium, wherein an air conditioning device for air conditioning of a medical treatment device coupled to the media supply arrangement is provided.

The invention discloses a self-adaptive hydrogel coupling agent as well as a preparation method and application thereof, belongs to the field of medical instruments, and particularly relates to a preparation method of the self-adaptive hydrogel coupling agent. The preparation method comprises the following steps: dissolving a main monomer, a functional monomer, a molecular weight regulator and a reinforcing filler in sterilized deionized water under dark and sterile conditions, carrying out a free radical polymerization reaction under the action of a persulfate solution and tetramethylethylenediamine, and carrying out dialysis and sterilization treatment to obtain the self-adaptive hydrogel coupling agent. The self-adaptive hydrogel coupling agent prepared by the invention eliminates tissue deformation caused by probe pressurization, significantly improves the accuracy of measurement of the actual distance of a target by ultrasound in an operation, and meanwhile, the self-adaptive hydrogel coupling agent is good in biocompatibility, can be sterile, is convenient to operate, and is suitable for open or endoscopic surgical wounds.

The invention provides a bacteriostatic and scale-inhibiting PE material and a preparation method thereof, and belongs to the technical field of high polymer materials, the preparation method comprises the following preparation steps: dissolving polyethylene in xylene, dissolving, adding perfluorohexylethylene and dicumyl peroxide, reacting, precipitating, washing, and drying to obtain perfluoro modified PE; the preparation method comprises the following steps: dissolving four-arm polyethylene glycol amine in a PBS buffer solution, adding 4-carboxyphenylboronic acid, EDC.HCl and NHS, carrying out a stirring reaction in a dark place, carrying out ultrafiltration and freeze drying to obtain PBA-PEG, dissolving the PBA-PEG in a Tris-HCl buffer solution, adding dopamine hydrochloride, and carrying out mixing, oxidation reaction, dialysis purification and drying to obtain a PBA-DA-PEG compound; the preparation method comprises the following steps: pre-mixing perfluorinated modified PE, mixing with an antioxidant and a compatibilizer, injecting the PBA-DA-PEG compound, continuously mixing, extruding, and carrying out water-cooling pelletizing to obtain the antibacterial and scale-inhibiting PE material. According to the PE material obtained by the invention, the antibacterial performance and the scale inhibition performance of the material can be improved at the same time.

The invention discloses construction of a near-infrared fluorescent carbon dot based on metformin. The carbon dot is synthesized from metformin and an amino acid compound through a one-pot hydrothermal method. The preparation method comprises the following steps: mixing the metformin and the amino acid compound, dissolving in an alkaline solution, carrying out ultrasonic dissolution, transferring the solution into a polytetrafluoroethylene inner container, putting the inner container into a stainless steel high-pressure kettle, and carrying out heating reaction in a muffle furnace. After the reaction is finished and a reaction system is cooled to room temperature, taking out the solution and centrifuging to obtain supernate; and then putting the supernate into a dialysis bag for dialysis purification, and after dialysis is finished, freeze-drying the solution to obtain the carbon dots MACDs disclosed by the invention. The prepared carbon dot has excellent biocompatibility and optical property adjustability, retains the characteristic structure of metformin, has near-infrared fluorescence emission, and can realize disease diagnosis of organisms.

The invention provides a preparation method of probiotic fermented polygonatum sibiricum polysaccharide, and belongs to the field of traditional Chinese medicinal material processing. The preparation method comprises the following steps: (1) adding cellulase and pectinase into polygonatum kingianum, carrying out water extraction, carrying out enzyme deactivation after water extraction, and carrying out suction filtration to obtain filtrate; (2) preparing bacillus DU-106 and lactobacillus plantarum nbk-MA2 into bacterial powder, and adding water to obtain bacterial liquid; mixing the bacterial liquid with the filtrate, fermenting, performing suction filtration, and centrifuging to obtain supernate; performing alcohol precipitation to remove protein; carrying out ethanol precipitation by using absolute ethyl alcohol again, collecting the precipitate after centrifuging, and carrying out redissolution, dialysis and freeze-drying to obtain fermentation modified crude polysaccharide; and (3) purifying the fermented and modified crude polysaccharide to obtain a purified polysaccharide component. The obtained probiotic fermented polygonatum sibiricum polysaccharide has the effect of losing weight, and can obviously improve the obesity characteristics of mice, specifically, reducing body weight, reducing fat, reducing serum liver lipid level, relieving serum liver inflammation of the mice, weakening blood glucose insulin sensitivity, repairing liver injury and the like.

The invention relates to the field of medical informatics, and provides a hemodialysis multi-mode risk closed-loop control system. Comprising a multi-source data acquisition module used for acquiring heterogeneous data in a dialysis process in real time; the space-time fusion engine module is used for carrying out space-time alignment and feature extraction of cross-modal data on the heterogeneous data by adopting a graph neural network architecture to generate a fusion feature vector; the dynamic risk prediction module is used for constructing a multi-dimensional risk assessment system based on the fusion feature vector, carrying out probability prediction on multiple risk types and outputting a prediction result; and the intelligent intervention control module evaluates the risk level according to the prediction result output by the dynamic risk prediction module, and generates an intervention strategy through a reinforcement learning algorithm. According to the invention, the timeliness and accuracy of intervention response are improved, and the incidence rate of dialysis complications is reduced.

The invention relates to the technical field of extracts, in particular to macromolecular dried longan pulp heteropolysaccharide with a blood sugar reducing characteristic and a preparation method and application thereof. The preparation method comprises the following steps: drying the longan pulp, homogenizing the dried pulp, adding distilled water, performing hot water extraction, filtering through gauze, and separating the dried longan pulp heteropolysaccharide with the blood sugar reducing characteristic and the molecular weight of more than 100kDa from the dried longan pulp by combining processes such as dialysis, ultrafiltration interception and the like. The dry longan pulp polysaccharide is extracted by adopting a hot water extraction method, the dry longan pulp polysaccharide is separated by adopting an ultrafiltration interception system device, the main component DLP of the dry longan pulp polysaccharide can inhibit starch digestive enzymes, model cell insulin resistance can be improved, and human intestinal flora composition can be changed. The beverage has the functions of reducing blood sugar and regulating intestinal flora.

Provided herein is a method of using digital twins for medical diagnosis, prediction, and / or prognosis of a disease or condition, such as diagnosis, prediction, and / or prognosis of one or more cancers, organ-specific age prediction, predicting of female aging, predicting hospital-acquired infection, predicting dialysis time series, predicting diabetes and complications, predicting pregnancy and child outcome, predicting heart failure, predicting myopia, predicting vision in anti-VEGF treatment, or any combination thereof. A system and non-transitory computer-readable storage medium configured for performing the method is also disclosed.

The invention provides a high-sensitivity ammonia gas sensor for early chronic kidney disease diagnosis and uremia dialysis curative effect monitoring, and relates to the field of exhaled gas analysis of diseases. The preparation method of the gas sensor comprises the following steps: S1, preparing I n2O3 nanofibers by an electrostatic spinning method; s2, the collected eggshell membranes are treated and cleaned so as to be used for a flexible substrate; and S3, growing an aniline monomer and the In2O3 nanofibers on the surface of the eggshell membrane in an in-situ chemical oxidation polymerization manner to prepare the polyaniline composite In2O3 nanofiber flexible film based on the eggshell membrane as the substrate. According to the method, the concentration difference of NH3 and creatinine in exhaled gas of a patient and a healthy person is analyzed, painless early diagnosis of the chronic kidney disease is achieved, the dialysis process is monitored painlessly and the curative effect is evaluated by analyzing the change of the concentration of NH3 in exhaled gas of a uremia patient in the dialysis process, and meanwhile the result is obtained through clinical tests. The response value of the sensor to exhaled gas has a good linear relationship with clinical indexes of creatinine and blood urea nitrogen representing the content of in-vivo metabolic nitrogen waste.

The invention discloses a process method for preparing high-spinning nano pyrite through physical field-chemical method coupling regulation and control, which comprises the following steps: dissolving bovine serum albumin in deionized water, adding an iron source, uniformly mixing, adjusting the pH value of the solution to 10.0-11.0, adding a sulfur source, and uniformly mixing, thereby obtaining the high-spinning nano pyrite. Carrying out a coupling regulation reaction of a physical field and a chemical method on the reaction system under the protection of inert gas, and then dialyzing and purifying to prepare the high-spin-state FeS2 nanosheet. The chemical method comprises one or more of a coprecipitation method, a solvothermal method and a hydrothermal method; the physical field comprises one or more of an alternating magnetic field, a static magnetic field and a rotating magnetic field. Through coupling regulation and control of a physical field and a chemical method, accurate conversion of the FeS2 nanosheet from a low spinning state to a high spinning state is realized, chemical doping can be effectively avoided, natural biological suitability of FeS2 is reserved, and the method has a good clinical conversion application prospect.

The invention relates to the crossing field of computer technology and edge calculation, and discloses a blood purification equipment real-time control method based on edge calculation. According to the method, multi-modal real-time physiological parameters, historical dialysis data and a current treatment target are fused through a local edge calculation unit, an individualized body fluid dynamic response prediction model is constructed, and an ultrafiltration rate instruction is optimized and generated within a millisecond level; the system comprises a multi-mode sensor array, a historical data storage module, a task planning interface, an edge computing unit and an ultrafiltration pump controller. According to the application, the hemodynamic state is accurately maintained, the risk of hypotension is remarkably reduced, and the treatment safety and individualization level are improved.

The method comprises the following steps: dissolving lipoic acid and a drug in an organic solvent to form a homogeneous solution, dropwise adding deionized water while stirring, then adding a reducing agent, initiating lipoic acid polymerization and drug co-assembly in situ at 20-40 DEG C to form a drug-loaded micelle solution, and carrying out freeze drying on the drug-loaded micelle solution to obtain the nano-preparation drug based on polylipoic acid. And dialyzing and purifying to obtain the nano preparation medicine based on polylipoic acid. The preparation method is characterized in that lipoic acid has dual characteristics of a drug carrier matrix and a dynamic crosslinking monomer, carrier synthesis and efficient drug encapsulation are synchronously realized through one-step in-situ polymerization-co-assembly, and the technical bottleneck that a traditional nano-carrier needs pre-synthesis and step-by-step drug loading is broken through. The method has the following practicability: (1) the process is simple and efficient, complex equipment is not needed, and reaction conditions are mild; (2) the drug loading performance is excellent, and the particle size is uniform and adjustable (50-300 nanometers); (3) a polylipoic acid skeleton endows the nano-drug preparation with environmental responsiveness, and intelligent drug release can be realized; and (4) the method is suitable for hydrophobic drugs and compound preparations. The method provides a high-load, high-stability and stimuli-responsive nanocrystallization solution for hydrophobic drug delivery, and has application value in the field of nano-medicines.

The invention relates to the technical field of intelligent monitoring, and particularly discloses an intelligent monitoring method and system for hemodialysis patient complications, and the method comprises the following steps: S1, carrying out the fusion to form a multi-modal feature set, S2, constructing an individualized risk feature map, S3, generating complication risk probability distribution, S4, calculating an individualized risk threshold value, and S5, generating an intervention suggestion sequence. The method comprises the following steps: acquiring physiological parameters of a hemodialysis patient and operation parameters of dialysis equipment, identifying a coupling relationship between the parameters, constructing an individualized risk characteristic spectrum, predicting a characteristic change trend, matching the characteristic change trend with a historical complication mode, calculating an individualized risk threshold to trigger early warning, generating targeted intervention suggestions, and monitoring an effect. According to the system, the accuracy and timeliness of hemodialysis complication monitoring are effectively improved, the complication occurrence rate is reduced, the workload of medical staff is relieved, and the safety and effectiveness of hemodialysis treatment are improved.

The invention discloses a selenium-rich polysaccharide-protein-polyphenol conjugate as well as a preparation method and application thereof, and belongs to the technical field of food processing. According to the method, hovenia acerba is taken as a raw material, the extraction efficiency is improved through organic solvent degreasing and two-stage dynamic extraction combined with ultrasonic pretreatment, a Na2HPO4 buffer solution and a sodium citrate buffer solution are adopted for step-by-step extraction and enzymolysis purification, and a polysaccharide-protein-polyphenol conjugate is obtained; a nano cellulose dispersion stabilizer and a light source with a specific wavelength are further introduced into a photocatalytic reaction, a selenium source and the conjugate are efficiently chelated, and finally the compound with the particle size of 80-120 nm and the selenium content of 3.5-4.5% is prepared through dialysis and freeze-drying. The obtained product has excellent oxidation resistance and hypoglycemic activity, can be applied to preparation of functional food or drugs for preventing and treating diabetes, is suitable for the fields of anti-inflammation, intestinal micro-ecological regulation and drug sustained-release carriers, and has high efficiency and safety.

The invention provides a radix tetrastigme polysaccharide and application thereof in a medicine for treating diabetic retinopathy. The radix tetrastigme polysaccharide is prepared by the following steps: deproteinizing a water extract of radix tetrastigme by using CaCl2, depigmenting by using activated carbon, performing column chromatography, eluting by using a NaCl solution, merging and collecting eluent components, concentrating under reduced pressure, dialyzing by using a dialysis bag with an interception value of 0.5 KDa, and performing vacuum freeze drying. And performing further chromatography by using Chromdex 200PG sephadex gel, collecting the components, and performing freeze drying to obtain the homogeneous polysaccharide with the average molecular weight of 36.848 KDa. Meanwhile, pharmacological activity evaluation is carried out on the radix tetrastigme polysaccharide, it is found that the polysaccharide can reduce the free Fe < 2 + > level and reverse high glucose induced ARPE19 cell damage, and in addition, animal experiments also prove that the radix tetrastigme polysaccharide can reduce the DR rat retina Fe < 2 + > level and relieve diabetic retinopathy; the research can provide a scientific basis for research and development of a novel natural medicine radix tetrastigme polysaccharide for treating DR.

The utility model relates to the technical field of water pollution treatment, in particular to a landscape water dialysis purification system. The system comprises a water intake pumping station, a water distribution well and a cloth filter tank, water taken by the water intake pumping station is conveyed into the water distribution well through a water inlet pipe of the water distribution well, the water inlet pipe of the water distribution well is connected with PAC and PAM pipelines, sewage is distributed into the cloth filter after being subjected to first flocculation and sedimentation in the water distribution well, PAM is added into a water outlet pipe of the water distribution well, pollutants in water are further subjected to flocculation and sedimentation in a flocculation and sedimentation section of the cloth filter, and the pollutants in the water are subjected to secondary flocculation and sedimentation. The sewage is filtered by the fiber rotary disc filter after two times of flocculating settling, and the filtered clear water can be discharged, so that the sewage is treated, the load of the fiber rotary disc filter is effectively reduced in the process, and the efficient treatment process of the sewage is ensured; sludge generated in the operation process of the system is collected and then filtered, so that the sludge produced by the system is treated.

The invention relates to the field, and discloses a dialysis concurrent risk dynamic assessment system, which comprises a data acquisition module, a data processing module and a data processing module, the data preprocessing module is used for carrying out abnormal value detection and processing on the multi-source data by adopting an isolated forest algorithm, and filling missing values in the multi-source data through an Attention-GAN network; the feature fusion module is used for performing feature fusion on the cleaned multi-source data by using a cross-modal attention fusion algorithm to generate a comprehensive feature vector; the model construction module is used for constructing a ResNet-GRU hybrid model based on the comprehensive feature vector and introducing a dynamic feature attention mechanism; the risk assessment module is used for inputting to-be-assessed patient data into the ResNet-GRU hybrid model to obtain a risk assessment result; according to the invention, the timeliness and accuracy of evaluation are obviously improved.

The utility model provides dialysis and separation equipment for umbilical cord blood. The dialysis and separation equipment comprises a first separation plate, a second separation plate, a bag and dredging units, wherein the first separation plate and the second separation plate are composed of filter membranes and impermeable membranes, the bag is made of flexible materials, and the dredging units are arranged on the two sides of the bag and used for squeezing. The filter membrane and the impermeable membrane are tightly combined to form an outlet, and the bag is divided into three cavities which are respectively used for treating umbilical cord blood and controlling liquid flow through a catheter and a valve. The dredging unit periodically extrudes the bag through the extrusion part and the control part, so that the filter membrane is prevented from being blocked. The equipment can effectively separate blood components through the matching of the filter membranes with different pore diameters and functions, and realizes a reliable, effective, simple and economical umbilical cord blood dialysis and separation mode.

The invention belongs to the field of functional food, health care products and medicines, and particularly relates to okra polysaccharide with a function of improving metabolic syndrome as well as a preparation method and application of the okra polysaccharide. The preparation method of the okra polysaccharide comprises the steps of pretreatment, alcohol soaking of raw materials, extraction of filtrate, alcohol precipitation, dialysis, concentration and freeze drying. The okra polysaccharide provided by the invention can improve metabolic syndrome indexes including obesity, hyperlipidemia, hyperglycemia, hypertension, liver inflammation, flora disorder and the like, the comprehensive improvement effect is better than that of commercial apple pectin, citrus pectin and inulin, and the okra polysaccharide can be used as prebiotics to enrich intestinal beneficial bacteria deficiency caused by metabolic syndrome. The sources of natural medicines and health-care products for preventing and treating the metabolic syndrome are widened.