3083 results about "Retina" patented technology

A near-to-eye display system for forming an image as an illuminated region on a retina of at least one eye of a user is disclosed. The system includes a source of modulated light, a proximal optic positionable adjacent an eye of the user to receive the modulated light. The proximal optic has a plurality of groups of optically redirecting regions. The optically redirecting regions are configured to direct a plurality of beams of the modulated light into a pupil of the eye to form a contiguous illuminated portion of the retina of the eye. A first group of the optically redirecting regions is configured to receive modulated light from the source and redirect beams of the modulated light into the pupil of the eye for illumination of a first portion of the retina. A second group of the optically redirecting regions is configured to receive modulated light from the source and redirect beams of the modulated light into the pupil of the eye for illumination of a second portion of the retina.

A display device is mounted on and / or inside the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display. The projected light propagates through the pupil but does not fill the entire pupil. In this way, multiple sub-displays can project their light onto the relevant portion of the retina. Moving from the pupil to the cornea, the projection of the pupil onto the cornea will be referred to as the corneal aperture. The projected light propagates through less than the full corneal aperture. The sub-displays use spatial multiplexing at the corneal surface. Various electronic devices interface to the eye mounted display.

A user can be challenged to provide at least one randomly selected biometric attribute. The randomly selected biometric attribute input by the user is automatically compared to a plurality of biometric attributes of the user contained in a user profile. The user can then be authenticated if the randomly selected biometric attribute input by the user matches at least one of the plurality of biometric attributes of the user contained in the user profile. Biometric attributes analyzed according to the methods and systems of the present invention, include, but are not limited to, for example, fingerprints, iris, retina, and / or tissue characteristics, such as skin morphology, skin layer thickness, collage density and orientation, tissue hydration, optical patent length differences, etc.

Embodiments of the present invention relate to an electro-active element having a dynamic aperture. The electro-active element provides increased depth of field and may be used in a non-focusing ophthalmic device that that is spaced apart from but in optical communication with an intraocular lens, a corneal inlay, a corneal onlay, a contact lens, or a spectacle lens that provide an optical power. The electro-active element provides increased depth of field and may also be used in a focusing or non-focusing device such as an intraocular optic, an intraocular lens, a corneal inlay, a corneal onlay, or a contact lens which may or may not have an optical power. By changing the diameter of dynamic aperture either increased depth of field or increased light reaching the retina may be achieved.

An artificial synapse array and virtual neural space are disclosed.More specifically, a cognitive sensor system and method are disclosed comprising a massively parallel convolution processor capable of, for instance, situationally dependent identification of salient features in a scene of interest by emulating the cortical hierarchy found in the human retina and visual cortex.

A display device is mounted on and / or inside the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display. The projected light propagates through the pupil but does not fill the entire pupil. In this way, multiple sub-displays can project their light onto the relevant portion of the retina. Moving from the pupil to the cornea, the projection of the pupil onto the cornea will be referred to as the corneal aperture. The projected light propagates through less than the full corneal aperture. The sub-displays use spatial multiplexing at the corneal surface.

The specification and drawings present a new apparatus and method for near-to-eye (e.g., retinal) displaying with exit-pupil expansion using a scanning component (e.g., a scanning mirror) and an exit-pupil expander (e.g., diffractive exit-pupil expander) for providing a retinal scanning display with a large exit pupil.

The invention discloses a fundus image retinal vessel segmentation method and a fundus image retinal vessel segmentation system based on deep learning. The fundus image retinal vessel segmentation method comprises the steps of performing data amplification on a training set, enhancing an image, training a convolutional neural network by using the training set, segmenting the image by using a convolutional neural network segmentation model to obtain a segmentation result, training a random forest classifier by using features of the convolutional neural network, extracting a last layer of convolutional layer output from the convolutional neural network, using the convolutional layer output as input of the random forest classifier for pixel classification to obtain another segmentation result, and fusing the two segmentation results to obtain a final segmentation image. Compared with the traditional vessel segmentation method, the fundus image retinal vessel segmentation method uses the deep convolutional neural network for feature extraction, the extracted features are more sufficient, and the segmentation precision and efficiency are higher.

A head mounted display system with at least one retinal display unit having a curved reflector positioned in front of one eye or both eyes of a wearer. The unit includes a first set of three modulated visible-light lasers co-aligned and adapted to provide a laser beam with selectable color and a first scanner unit providing both horizontal and vertical scanning of the laser beam across a portion of the curved reflector in directions so as to produce a reflection of the color laser beam through the pupil of the eye onto a portion of the retina large enough to encompass the fovea. The unit also includes a second set three modulated visible-light lasers plus an infrared laser, all lasers being co-aligned and adapted to provide a color and infrared peripheral view laser beam, and a second scanner unit providing both horizontal and vertical scanning of the visible light and infrared laser beams across a portion of the curved reflector in directions so as to produce a reflection of the scanned color and infrared laser beams through the pupil of the eye onto a portion of retina corresponding to a field of view of at least 30 degrees×30 degrees.

A display apparatus that displays an image on a retina of a user, the display apparatus comprising: an image output unit (100) which includes a light source (101, 110), a wavefront shape change unit (102, 109), and a scan unit (103, 108) and is configured to output display light for displaying the image; and a deflection unit (104, 107) configured to deflect, toward an eye of the user, the display light outputted by the image output unit (100). The deflection unit (104, 107) has a deflection characteristic of suppressing image distortion caused by a change in relative position of the deflection unit (104, 107) with respect to a pupil of the user.

The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.

Provided is an apparatus for driving an artificial retina using a medium-range power transmission technique. The apparatus can wirelessly transmit power to an artificial retina circuit within a medium range of about 1 m using resonance between a first coil equipped around a user's waist and a second coil implanted in a user's eye. Thus, it is possible to solve the difficulty of implanting a coil in a lens, provide convenience to a user by eliminating the necessity of artificial glasses, and stably supply power to the artificial retina circuit. In addition, it is possible to remarkably lessen the difficulty in connecting the second coil with the artificial retina circuit in an eye.

Surgical correction of human eye refractive errors such as presbyopia, hyperopia, myopia, and stigmatism by using transcutaneously inductively energized artificial muscle implants to either actively change the axial length and the anterior curvatures of the eye globe. This brings the retina / macula region to coincide with the focal point. The implants use transcutaneously inductively energized scleral constrictor bands equipped with composite artificial muscle structures. The implants can induce enough accommodation of a few diopters, to correct presbyopia, hyperopia, and myopia on demand. In the preferred embodiment, the implant comprises an active sphinctering smart band to encircle the sclera, preferably implanted under the conjunctiva and under the extraocular muscles to uniformly constrict the eye globe, similar to a scleral buckle band for surgical correction of retinal detachment, to induce active temporary myopia (hyperopia) by increasing (decreasing) the active length of the globe. In another embodiment, multiple and specially designed constrictor bands can be used to enable surgeons to correct stigmatism. The composite artificial muscles are either resilient composite shaped memory alloy-silicone rubber implants in the form of endless active scleral bands, electroactive ionic polymeric artificial muscle structures, electrochemically contractile endless bands of ionic polymers such as polyacrylonitrile (PAN), thermally contractile liquid crystal elastomer artificial muscle structures, magnetically deployable structures or solenoids or other deployable structures equipped with smart materials such as preferably piezocerams, piezopolymers, electroactive and eletrostrictive polymers, magnetostrictive materials, and electro or magnetorheological materials.

An apparatus and method for safely cannulating a blood vessels, including but not limited retinal blood vessels, is described. In one embodiment, the apparatus can consist of a micropipette / microcannula, micromanipulator and positioner mounted to a base, which is attached to a wrist rest commonly used in eye surgery. The micropipette / microcannula is connected to tubing such that a medication may be injected through the micropipette / microcannula into the blood vessel or conversely, a small quantity of material may be removed from a blood vessel. Alternatively, a catheter, wire or stent may be placed through the micropipette / microcannula to treat or diagnose an area remote from the insertion site. The ability to cannulate a retinal blood vessel should be efficacious in the treatment of vein and artery occlusion, ocular tumors and other retinal, vascular and optic nerve disorders that would benefit from diagnosis and / or treatment. In another embodiment, a self-sealing needle is provided which allows the perforation of a blood vessel or other structure and the minimization of hemorrhaging when the needle is withdrawn from the blood vessel / structure. Another embodiment discloses an ocular implant needle.

The present invention provides systems and methods for screening and tracking ophthalmic disease in a plurality of patients. The invention includes a screening subsystem comprising a non-mydriatic camera for obtaining digital images of eyes of the patients, a central database for storing the digital images of the eyes of patients as well as patient demographic data and related health data, and a central server comprising a computer which executes retinopathy grading algorithms, wherein the retinopathy grading algorithms recognize and assign a grade to ophthalmic disease present in the digital eye image and store the results in the central database. The invention also provides a method for screening and tracking ophthalmic disease in a patient with the steps of obtaining digital images of eyes of the patient by means of a screening subsystem comprising a camera, transmitting the obtained digital image to a central database and to a central server, executing retinopathy grading algorithms that recognize and assign a grade to ophthalmic disease present in the digital eye images, and storing the transmitted digital images and the results of the retinopathy grading algorithms in the central database.

In accordance with embodiments of the present invention a present authentication or identification process includes iterative and successive cross-hatching of biometric components such as voice print, fingerprint, hand analysis, retina scan, iris scan, and / or features (such as facial characteristics, scars, tattoos and / or birthmarks) with other identifying data such as a PIN, password phrase, barcode, or identification card.

A display device (e.g., in a contact lens) is mounted on the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display. Additionally, a “locally uniform resolution” mapping may be used to model the variable resolution of the eye. Accordingly, various aspects of the display device may be based on the locally uniform resolution mapping. For example, the light emitted from the sub-displays may be based on the locally uniform resolution mapping.

Embodiments provide method and systems for determining or measuring objective eye alignment in an external-coordinate system so as to define a reference axis. Additional embodiments provide a method and system of aligning an objectively determined reference axis of the eye in a selected relationship to a therapeutic axis of an ophthalmic therapeutic apparatus and / or a diagnostic axis of an ophthalmic diagnostic apparatus. Embodiments provide a method and system for planning an ophthalmic treatment procedure based on objective eye alignment in an external-coordinate system so as to define a reference axis of an eye to be treated. The reference axis may be used to position a therapeutic energy component, for example, an orthovoltage X-ray treatment device, e.g., positioned to provide treatment to tissue on the retina, such as the macula.

System and method for generating patterns P of aiming and treatment light on target eye tissue (e.g. the retina) of a patient's eye. The system includes light sources for treatment and aiming light, a scanner for generating patterns of spots of the generated light, a controller, and a graphic user interface that allows the user to select one of several possible spot patterns, adjust the spot density and / or spot size, and apply patterns with fixed or varied density. The patterns can be formed of interlaced sub-patterns and / or scanned without adjacent spots being consecutively formed to reduce localized heating. Partially or fully enclosed exclusion zones within the patterns protect sensitive target tissue from exposure to the light.

A wearable display device is described that allows the image from a semi-transparent display screen placed close to the eye to be correctly focused onto the retina while simultaneously allowing the image from the external environment to pass through the device without significant aberration. Focus of the display screen image is achieved through use of a micro-lens array between the screen and the eye, and a separate set of micro-lens arrays on the distant side of the screen in conjunction with the micro-lens array on the near side of the screen allows the external environmental image to pass through. In this manner images from the display screens can overlay the eye's usual view of the external environment. Use of micro-lens arrays that have dynamically adjustable focus properties allow for simulated three-dimensional images and corrective optics for far- or near-sightedness.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

A system performing secondary verification using only existing apparatuses to accomplish a measure for relief in personal authentication without causing complexity or without increasing cost. The system has a registering apparatus for obtaining data for verification from information inputted using an inputting unit and registering the data. The registering apparatus has a first extracting unit for extracting biometrics characteristic data from the biometrics information obtained by the inputting unit, and registering the biometrics characteristic data as registry biometrics characteristic data for primary verification, and a second extracting unit for extracting data, which is different from the registry biometrics characteristic data, from information inputted using the inputting unit and registering the data as registry data for secondary verification. The system is used for personal authentication using biometrics information such as fingerprint, palm print, finger shape, palm shape, voice, retina, iris, face image, dynamic signature, blood vessel pattern, keystroke, or the like.

The invention discloses an attention mechanism-based in-depth learning diabetic retinopathy classification method comprising the following steps: a series of eye ground images are chosen as original data samples which are then subjected to normalization preprocessing operation, the preprocessed original data samples are divided into a training set and a testing set after being cut, a main neutralnetwork is subjected to parameter initializing and fine tuning operation, images of the training set are input into the main neutral network and then are trained, and a characteristic graph is generated; parameters of the main neutral network are fixed, the images of the training set are adopted for training an attention network, pathology candidate zone degree graphs are output and normalized, anattention graph is obtained, an attention mechanism is obtained after the attention graph is multiplied by the characteristic graph, an obtained result of the attention mechanism is input into the main neutral network, the images of the training set are adopted for training operation, and finally a diabetic retinopathy grade classification model is obtained. Via the method disclosed in the invention, the attention mechanism is introduced, a diabetic retinopathy zone data set is used for training the same, and information characteristics of a retinopathy zone is enhanced while original networkcharacteristics are reserved.

A system and method are presented for use in imaging the patient's retina. A light source unit is provided including a light emitting diode (LED) arrangement comprising multiple LEDs of different wavelength ranges. A light guide arrangement is used with the LEDs arrangement and is configured for coupling light from the LEDs and providing output light beams of a desired shape. The illuminating light is directed towards a region on the retina, and light returned from the illuminated region is collected and directed to an image detector unit. The invention enables the use of LED light at high intensity as required in the eye retina imaging, while maintaining the required high-quality imaging. Also, the invention provides for simultaneous or quasi-simultaneous as well as high-speed imaging in FA and ICG imaging procedures, thereby satisfying a long felt need in ophthalmology. Also, the invention provides for automated illumination or light exposure control to optimize overall light exposure to the patient eye and best acquired image quality in terms of brightness, contrast and image signal-to-noise ratio.

The invention is directed to an implantable device to enable delivery of drugs to the retina. The device minimizes stress to the retina by virtue of its softness and smooth shape that conform to the retina. Drugs are delivered by osmosis or by the device dissolving. It may be connected to an externally mounted pump and drug reservoir that control the amount of drug. It contains one or more holes that are positioned to deliver drugs to the desired location. Drugs may stimulate the retina to enable vision in blind patients. Drugs may be injected directly inside the eye by a trans-scleral pump and valve drug delivery device.

The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are absorbed by rhodopsin and with the intensity of the light varying in a prescribed temporal manner. The light reflected from the retina is detected to provide a signal corresponding to the intensity of the detected light, and the detected light signal is analyzed to determine the changes in form from that of the illuminating light. For a biased sinusoidal illumination, these changes can be expressed in terms of harmonic content of the detected light. The changes in form of the detected light are related to the ability of rhodopsin to absorb light and regenerate, which in turn is related to the concentration of blood glucose, allowing a determination of the relative concentration of blood glucose. Other photoreactive analytes can similarly be determined by projecting time varying illuminating light into the eye, detecting the light reflected from the retina, and analyzing the detected light signal to determine changes in form of the signal due to changes in absorptivity of a photoreactive analyte.

A display device is mounted on and / or inside the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display. The projected light propagates through the pupil but does not fill the entire pupil. In this way, multiple sub-displays can project their light onto the relevant portion of the retina. Moving from the pupil to the cornea, the projection of the pupil onto the cornea will be referred to as the corneal aperture. The projected light propagates through less than the full corneal aperture. The sub-displays use spatial multiplexing at the corneal surface. Various electronic devices interface to the eye mounted display.