4 results about "Micromanipulator" patented technology

A micromanipulator (1) for manipulating a laser beam (L in , L scan ) of a laser surgery device, comprising a scanner (10) for generating at least one scan figure (60) and at least one control element for controlling the scanner (10), wherein the control element comprises a rotating element (51), wherein a rotation (D d) of the rotating element (51) causes a rotation (D s) of the scan figure (60), which depends on the size and / or speed of the rotation (D d) of the rotating element (51), wherein the rotating element (51) can rotate freely without limiting the angle of rotation and the scan figure (60) follows this free rotation without restrictions, and a laser surgery device with said micromanipulator (1).

This invention discloses an automated cell manipulation method and system guided by artificial intelligence, comprising: identifying and locating the biological target object to be manipulated based on real-time images acquired by a microscopic imaging system to obtain target position information; calibrating and tracking the end-effector position of a micromanipulator based on the real-time images to obtain the real-time end-effector position; planning and dynamically correcting the motion trajectory of the micromanipulator based on the target position information and the real-time end-effector position until the end-effector reaches the preset target operation position, and controlling the micromanipulator to execute a preset interactive operation; verifying the operation result based on the real-time image after the operation to obtain the verification result, and controlling subsequent processes based on the verification result. This invention overcomes the inherent defects of traditional manual operation and semi-automated solutions in microscale cell manipulation through an end-to-end intelligent process, achieving high-precision, high-throughput, high-success-rate, and highly standardized cell manipulation.

There is provided a microscope comprising a micromanipulator, comprising a first electromagnet comprising a first magnetic core; a second electromagnet comprising a second magnetic core, wherein the first magnetic core and the second magnetic core are configured to generate a magnetic force on magnetic probes arranged within a biological matrix arranged in between the first magnetic core and the second magnetic core; and wherein the microscope comprises imaging means configured to capture images of the biological matrix comprising the magnetic probes for detection of displacements of the magnetic probes caused by the magnetic force.

An automatic end effector tip position initialization mechanism for a micromanipulation system is provided. The method includes: S1, positioning a macro end effector tip, calculating a camera pose by using ArUco Tag, and realizing a three-dimensional positioning of the end effector tip by using a triangulation method, and moving the end effector to a area near a center of a focal plane based on a visual servo; S2, positioning a micro end effector tip; S3, acquiring calibration data based on a visual servo, calibrating the end effector tip and the petri dish, and obtaining a left calibration matrix and a right calibration matrix reflecting the transformation relationship between left and right micromanipulator coordinates and image coordinates; generating an intuitive human-computer interaction interface based on a mouse and a keyboard according to acquired position information. The method has obvious advantages in terms of operation accuracy, operation efficiency and repeatability.