2793 results about "Hydrate" patented technology

The invention discloses a novel synthetic method for 5-phenyl tetrazole, which includes the following steps: firstly performing acid neutralization to hydrazine hydrate; then adding mixing solution formed by cyanobenzene, water and ethyl alcohol to generate phenyl aminoguanidine salt; adopting sodium nitrite for diazotization to obtain nitrine amidine under the acidic condition; obtaining 5-phenyl tetrazole crude product through closed loop under the alkaline condition; obtaining 5-phenyl tetrazole acceptable product through adopting ethyl alcohol for refining. The method has the advantages of simple technology, simplicity in operation and high product yield.

The invention belongs to the technical field of metal powder preparation, and discloses a method for preparing silver powder through reduction of hydrazine hydrate with the adjustable particle size. The preparation method comprises the following steps that a first dispersing agent is dissolved in deionized water, a silver-ammonia solution and a hydrazine hydrate solution are sequentially added, stirring reaction is conducted, and nano-silver seed crystal sol is obtained; uniformly mixing the obtained nano-silver seed crystal sol with a hydrazine hydrate solution and a second dispersing agent to obtain a reducing base solution; adding a surface modifier into absolute ethyl alcohol, and uniformly dissolving to obtain a surface modification coating solution; preparing a silver-ammonia solution, adding the prepared silver-ammonia solution into the reducing base solution, then adding the surface modification coating solution, and stirring for reaction to obtain silver powder slurry liquid; and after solid-liquid separation, a solid phase is taken, washed and dried, and silver powder is obtained. The preparation method is simple in process, the particle size of the silver powder can be adjusted through the adding amount of the seed crystal, and the prepared silver powder particles are uniform in particle size distribution, high in dispersity and suitable for the fields of conductive silver paste, electronic packaging and the like.

The invention relates to the technical field of building materials, and particularly discloses a high-performance solid-waste-based grouting material and a preparation method thereof. Comprising the following raw materials in parts by weight: 32 to 54 parts of Portland cement, 12 to 16 parts of a modified admixture, 2.4 to 3.6 parts of a functional filler, 42 to 56 parts of aggregate, 45 to 55 parts of a photoinitiator solution, 0.6 to 0.8 part of a water reducing agent, 0.9 to 1.1 parts of a composite expanding agent, 0.04 to 0.06 part of a defoaming agent and 9.2 to 12.4 parts of deionized water. Siloxane groups, acylamino groups, ester groups and benzene rings are chemically bonded on the surface of the modified admixture, so that the hydrophilicity of the modified admixture is reduced, the modified admixture can form hydrogen-bond interaction with hydroxyl groups and cement hydrates on the functional filler, and meanwhile, a flexible long-chain alkane structure on the functional filler can be entangled with the modified admixture, so that the flexibility of the modified admixture is improved. The mechanical property, the durability and the fluidity of the grouting material are improved.

The invention relates to a preparation method and application of an inner-rigid outer-soft core-shell structure silicon dioxide blocking agent for marine drilling fluid, and belongs to the field of deepwater oil and gas drilling. N-vinyl-2-pyrrolidone, dimethyl diallyl ammonium chloride, acrylamide and 2-acrylamide-2-methylpropanesulfonic acid are polymerized and grafted on the surface of nano silicon dioxide to form the silicon dioxide blocking agent with a core-shell structure and a rigid inside and a soft outside; by means of rigid plugging of a nano material and deformation filling flexible plugging of a high-molecular polymer, shale micro-nano pores are efficiently plugged with rigid inside and flexible outside, so that the stability of a well wall is maintained, meanwhile, secondary generation of hydrates is effectively inhibited, and the safety and efficiency of deepwater drilling are improved; the plugging agent provided by the invention reduces the demand on a large number of thermodynamic inhibitors, not only saves the cost, but also has the characteristic of environmental protection.

The present disclosure provides crystalline forms, solvates and hydrates of (R)-5-fluoro-2-methyl-1-((R)-5-(pyridin-2-yl)-2,3-dihy dro-lH-indene-2-carbonyl)indoline-6- sulfonamide, and methods of making.

Provided herein, in part, is a compound of Formula (I)or a hydrate thereof,essentially free of one or more impurities, compositions thereof, and methods of use thereof.

Provided herein are new crystalline form of the compound of formula (A), which is a hydrate, and its pharmaceutical composition and use of the same in treating cancer.

Provided herein is a process comprising heating a composition comprising (P)-compound A or a salt thereof and a solvent to a temperature of 250° C. to 350° C. to form racemized compound A. Also provided is a process for isolating (P)-compound A from a composition comprising (P)-compound A and a tartrate, as described herein. Further provided herein, is a process for isolating a free acid of a tartrate or a hydrate thereof from a composition comprising a tartrate, (P)-compound A, and an organic solvent.

To provide an environmental test apparatus capable of performing a long-term deterioration test in which a test sample is exposed for a long period to methane-dissolved water under a low-temperature, high-pressure environment simulating a seafloor environment.SOLUTION: An environmental test apparatus 100 according to an embodiment is an environmental test apparatus for performing a long-term deterioration test in which a test sample is exposed to methane-dissolved water under an environment simulating a seafloor environment where methane hydrate is present and includes: a pressure-resistant vessel 110 which houses the test sample and in which the methane-dissolved water at a temperature and pressure corresponding to the seafloor environment flows through the test sample; a cooling unit 120 that cools and maintains the pressure-resistant vessel 110 at the temperature; and a pressurizing circulation unit 130 that pressurizes the methane-dissolved water flowing out from an outlet 110b of the pressure-resistant vessel 110 and sends it toward an inlet 110a of the pressure-resistant vessel 110.SELECTED DRAWING: Figure 1

The invention belongs to the technical field of heating bodies, and particularly relates to a method for preparing a sheet-shaped heating body. The preparation method comprises the following steps: stirring and dissolving lanthanum nitrate, strontium nitrate, manganese nitrate hexahydrate and a solvent to obtain a metal salt solution; preparing the metal salt solution into a precursor, wherein the precursor is a precursor solution or precursor sol; and carrying out tape casting and drying on the precursor to obtain a biscuit sheet, and carrying out glue removal treatment and sintering on the biscuit sheet to obtain the sheet-shaped heating body. According to the preparation method, a precursor system is optimized, the dispersion stability of the precursor is improved, casting, drying and sintering processes are matched, the problem of powder agglomeration is solved, the defects of green bodies are reduced, the drying shrinkage rate of green body pieces in the preparation process is reduced, the surface roughness is reduced, the stability and heat output uniformity of a heating body are improved, and the compactness is improved.

Provided herein is a synthesis for omecamtiv mecarbil dihydrochloride hydrate and various intermediates. (1)

The invention provides a hydrated compound and a preparation method thereof, and relates to the technical field of compound preparation. The hydrated compound is rupatinifen fumarate monohydrate and has a crystal structure. The preparation method of the hydrated compound comprises the following steps: adding rupatinifen fumarate into a reaction solvent at least containing a first organic solvent, heating, stirring and refluxing until the rupatinifen fumarate is completely dissolved, the concentration of the rupatinifen fumarate in a reaction system is not lower than 70% of the concentration of a saturated solution of the rupatinifen fumarate in the reaction system, and carrying out solid-liquid separation to obtain the hydrated compound. And continuously refluxing for 1 min to 24 h, cooling to the temperature not exceeding 8 DEG C, crystallizing, collecting crystals, washing and drying to obtain the product.

The present invention discloses a method for preparing highly dispersible submicron spherical palladium powder. The method comprises the following steps: first, weighing solid palladium nitrate and dissolving it in dilute nitric acid to prepare a dilute palladium nitrate solution; then dissolving a reducing agent in deionized water to obtain a reducing solution; then weighing a dispersant and an additive and dissolving them in deionized water to obtain a mixed base solution; and then mixing the three to obtain a reaction slurry containing palladium powder. The mixture is then filtered, washed, and dried to obtain submicron spherical palladium powder particles. The present invention adopts a liquid phase reduction method to reduce the palladium nitrate solution with ascorbic acid or hydrazine hydrate as a reducing agent to prepare the submicron spherical palladium powder. An organic polymer dispersant and a small molecule alcohol additive are simultaneously added to the base solution in a symmetrical manner. While ensuring the yield of palladium powder, the particle growth process and dispersibility are well controlled. The prepared palladium powder particles are spherical and highly dispersed, with a particle size of 100 to 600 nm.

An advantageous isolated morphic form of trilaciclib which is 2′-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7′,8′-dihydro-6′H-spiro[cyclohexane-1,9′-pyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyrimidin]-6′-one, for example in the form of a dihydrochloride salt or a dihydrochloride, dihydrate.

The invention discloses a hydrate-containing porous medium resistivity model construction method considering hydrate heterogeneous distribution, and the method comprises the following steps: 1) manufacturing a rock core according to the rock composition of a target hydrate reservoir, and scanning the pore throat structure of the rock core through CT; 2) generating a hydrate in the core, and scanning the occurrence state of the hydrate through CT (Computed Tomography); 3) establishing a digital core model based on CT scanning data, and applying an electrostatic field; 4) changing hydrate saturation parameters in the model, and calculating the resistivity of the model through numerical simulation; 5) calculating the critical water saturation of the hydrate; and (6) fitting by taking the critical water saturation as a boundary to obtain a resistivity segmentation calculation model. According to the method, a hydrate-containing porous medium resistivity model is established based on a real rock core size, and an electric field simulation means is utilized to calculate a hydrate-containing porous medium resistivity value. In combination with CT scanning data, an undetermined coefficient of a porous medium resistivity calculation formula in a hydrate thermal decomposition experiment is obtained through electric field simulation, and a basis is provided for hydrate reservoir electric heating development.

The invention provides a fluidization two-field coupled natural gas hydrate exploitation simulation method and system, and relates to the field of natural gas hydrate exploitation. A fluidization two-field coupled natural gas hydrate exploitation simulation method comprises the following steps: establishing a geometric model of a natural gas hydrate reservoir on the basis of reservoir parameters and physical parameters of the natural gas hydrate reservoir; based on a mass conservation equation, establishing a control equation set of the natural gas hydrate fluidization two-field coupling model; adjusting the control equation set based on the intrinsic dynamic behavior of the natural gas hydrate phase change decomposition and the two-phase seepage law of the natural gas hydrate to obtain a target control equation set; based on initial conditions and boundary conditions, solving the target control equation set to obtain two-phase seepage field and chemical decomposition field distribution; based on the distribution of the two-phase seepage field and the chemical decomposition field, calculating the accumulated decomposition, water production and gas production quality of the natural gas hydrate. Therefore, simulation accuracy can be improved, and engineering practicability is facilitated.

The invention relates to the technical field of metal material hot working, and discloses a hot-rolled coiled plate production process which comprises the following steps: preparing a reaction type protective agent, the high-temperature-resistant coating is prepared from the following raw materials in parts by weight: 20 to 40 parts of tetraethoxysilane, 5 to 15 parts of triethyl phosphate, 1 to 5 parts of triethyl borate, 0.5 to 2.0 parts of cerous nitrate (III) hexahydrate, 0.1 to 1.0 part of lithium acetate and 0.01 to 0.05 part of vanadyl acetylacetonate (IV). Coating the surface of a hot-rolled plate blank with the protective agent; the coated plate blank is heated in a heating furnace, so that the protective agent forms a molten-state protective layer in situ; carrying out hot rolling on the plate blank with the molten protective layer; and cooling and coiling the hot-rolled steel strip. In the whole heating and hot rolling process, the molten protective layer isolates the contact between the steel and the oxidizing atmosphere, so that the generation of oxide scales is fundamentally inhibited, the production process is simplified, and the metal yield is increased.

The invention discloses a preparation method of pyridinetriazolone, and belongs to the technical field of organic synthesis, and the preparation method comprises the following steps: taking hydrazine hydrate as a starting raw material, adding urea in batches at the temperature of 80-85 DEG C, carrying out heat preservation reaction to obtain semicarbazide, dropwise adding hydrochloric acid to form salt, and drying under reduced pressure to obtain semicarbazide hydrochloride; adding the semicarbazide hydrochloride obtained in the previous step and 2-chloropyridine into an ethylene glycol monomethyl ether system, heating to 130-135 DEG C, refluxing, adding a catalytic amount of concentrated sulfuric acid, and carrying out heat preservation reaction to obtain pyridine triazolone; and drying the post-treated mother liquor under reduced pressure, weighing, adding quantitative urea, heating to 130-135 DEG C, and reacting to obtain the pyridinium triazolone. The initial raw materials are hydrazine hydrate and urea, are common industrial raw materials, are easy to obtain and low in price, and are beneficial to industrial production; the by-product 2-hydrazinopyridine is recovered and reacts with urea to prepare the pyridintriazolone, so that the raw material utilization rate and the product yield are greatly improved, the total yield reaches more than 80%, and the purity of the pyridintriazolone is more than or equal to 99.0%.

An advantageous isolated morphic form of trilaciclib which is 2′-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7′,8′-dihydro-6′H-spiro[cyclohexane-1,9′-pyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyrimidin]-6′-one, for example in the form of a dihydrochloride salt or a dihydrochloride, dihydrate.

An advantageous isolated morphic form of trilaciclib which is 2′-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7′,8′-dihydro-6′H-spiro[cyclohexane-1,9′-pyrazino[1′,2′:1,5]pyrrolo[2,3-d]pyrimidin]-6′-one, for example in the form of a dihydrochloride salt or a dihydrochloride, dihydrate.

The present invention discloses a preparation method and application of a Bi2O2S / Bi 12 TiO 20 composite photocatalytic material, which includes weighing Bi2O3 and titanium dioxide, grinding them evenly, putting them into a muffle furnace, heating to 700 °C, maintaining the temperature for 6 - 8 h, and then naturally cooling to room temperature to obtain Bi 12 TiO 20 catalyst; dispersing Bi 12 TiO 20 in deionized water, adding a hydrazine hydrate solution of thiourea, stirring, adding KOH and NaOH, stirring well, standing, centrifuging, washing the centrifuged product alternately with water and ethanol, and drying to obtain Bi2O2S / Bi 12 TiO 20 composite photocatalyst. The present invention adopts the normal temperature standing method, and the energy consumption during the synthesis process is low; the Bi2O2S / Bi 12 TiO 20 composite material is a block-coupled sheet combination structure, and the combination of the two materials can greatly improve the separation efficiency of electron-hole pairs and has excellent performance in photocatalytic degradation of 2,4-dichlorophenol.

The present invention provides a manganese metal-organic framework material with oxidase properties, a preparation method, and an application thereof. The material is prepared by the following method: using 1,3,5-trimethic acid as an organic ligand, manganese acetate tetrahydrate as a manganese source, and a water-ethanol solution as a solvent, to obtain a manganese metal organic framework (MOF) precursor via a solvothermal synthesis technique; the manganese MOF precursor is post-synthetically modified using an oxidant, wherein the oxidant is a mixed solution of an aqueous alkali metal hydroxide solution and H2O2, and the ratio of the manganese MOF precursor to the alkali metal hydroxide is (400-600) mg:(0.5-2) mmol. By using specific types and amounts of manganese MOF precursors and oxidants, the resulting metal-organic framework nanomaterial has specific enzyme-like properties, can exert the function of uricase, and has optimal and high uricase activity under neutral pH conditions.

The invention discloses a process and equipment for recovering platinum and palladium from a petroleum catalyst, and relates to the field of metal material recovery, carbon-supported platinum group noble metals platinum and palladium are recovered by using the patent technology, firstly, fine grinding, hydrolysis and filtration are performed, then a reducing agent is adopted for reduction, then acidification and filtration are performed to remove base metals, and hydrochloric acid and nitric acid solutions are adopted for leaching and saltpeter removal, so that the platinum and palladium are recovered. The high-purity palladium powder is prepared from the solution subjected to platinum precipitation through ammonium chloride platinum precipitation, ammonium chloroplatinate hydrazine hydrate reduction, high-purity platinum powder and ammonia water palladium precipitation and hydrazine hydrate reduction, the purposes of saving energy and reducing the production cost are achieved, the ashing roasting furnace is adopted for static ashing, the technology process is simplified, the platinum group precious metal recovery rate is high, and the smelting cost is low. And the quality and purity of the platinum-palladium product are high, the metal recovery rate is high, and the smelting cost is low.

The invention belongs to the technical field of nano composite materials, and discloses a novel transition metal-inserted transition metal sulfide composite rare earth oxide photocatalytic material with a solid mediator Z-type heterostructure, and a preparation method and application of the novel transition metal-inserted transition metal sulfide composite rare earth oxide photocatalytic material. The preparation method comprises the following steps: mixing transition metal salt, thioacetamide, nitrate hexahydrate and water to obtain a mixed solution 1; mixing the mixed solution 1 with a hydrazine hydrate solution, and performing hydrothermal reaction to obtain a mixed solution 2; mixing the mixed solution 2 with ammonia water, and sequentially carrying out hydrothermal reaction, drying and calcining to obtain a calcined product; and mixing the calcined product with a sodium borohydride aqueous solution, and drying to obtain the photocatalytic material. The obtained photocatalytic material of the transition metal inserted transition metal sulfide composite rare earth oxide with the solid mediator Z-type body heterostructure has the characteristics of high stability, safe interface contact and rapid charge migration.

The present invention relates to an activator for cementless binders comprising: a silicate of an alkali metal or alkaline earth metal or a hydrate thereof; a carbonate of an alkali metal or alkaline earth metal or a hydrate thereof; and a hydroxide of an alkali metal or alkaline earth metal or a hydrate thereof. The invention also relates to a cementless binder comprising said activator and to a cementless cementitious material comprising said cementless binder. Compared with the traditional ordinary Portland cement, the building material containing the cement-based cementing material has better compressive strength and has the characteristic of environmental protection.

The invention discloses an aluminum alloy surface and a treatment method thereof, and relates to the technical field of aluminum alloy surface treatment.The treatment method comprises the steps that the surface of an aluminum alloy is cleaned, subjected to chemical pretreatment, subjected to pulse anodic oxidation and then subjected to sealing treatment; an electrolyte used for anodic oxidation comprises the following components in percentage by mass: 10%-30% of sulfuric acid, 0.5%-1% of tea polyphenol, 0.1%-0.3% of cerous nitrate and 0.2%-0.5% of nano aluminum oxide; the confining liquid for confining is prepared from the following components in percentage by mass: 0.5 to 1 percent of chitosan particles, 0.2 to 0.5 percent of nano zinc oxide and 0.1 to 0.3 percent of cerium complex; wherein the cerium complex is cerium oxalate or cerium acetylacetonate hydrate. According to the aluminum alloy surface treatment method, the surface of the aluminum alloy matrix contains the pulse oxide layer and the closed film layer, and the formed aluminum alloy surface has good mechanical performance, insulating performance and anti-aging performance.

The invention discloses a method for efficiently preparing furfural and glucose from forest grass biomass. The method comprises the following steps: mixing a forest grass biomass raw material, a molten salt hydrate and an organic solvent, and carrying out a pretreatment reaction to obtain a furfural-containing pretreatment solution and pretreatment residues; mixing the pretreated residues, sulfuric acid and molten salt hydrate, and then performing hydrolysis reaction to obtain hydrolysate containing glucose; the method for preparing furfural and glucose from forest grass biomass provided by the invention is simple, convenient to operate, environment-friendly, short in time, high in yield, economical and efficient, and has a wide industrial application prospect.

The invention relates to a targeted carbonic anhydrase radiopharmaceutical, in particular to a compound which is a compound as shown in a formula I or a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt or a prodrug of the compound as shown in the formula I, the compounds are capable of inhibiting carbonic anhydrase IX or diagnosing and / or treating one or more tumors, cancers or cells expressing carbonic anhydrase IX. # imgabs0 #

The present invention generally relates to a process for fabricating a reduced graphene oxide (rGO)-based antifouling marine coating is disclosed. The process begins with preparing a dispersed graphene oxide solution, followed by chemical reduction using hydrazine hydrate at 90-95° C. for 3 hours to form a dispersed rGO solution. This solution is then washed, filtered, and sonicated for 6 hours to ensure stability. A polymer solution is prepared by dissolving 40-50 wt % epoxy resin in acetone at 50° C. The antifouling composite is then formed by combining the rGO solution, 10-15 wt % zinc oxide nanoparticles, and 1-5 wt % carbon nanotubes with the polymer solution, followed by 6 hours of sonication at room temperature. Finally, the resulting composite material is applied to a substrate as a coating using spraying, brushing, dipping, or spin coating. This coating offers a promising solution for preventing biofouling on marine structures.