73 results about "Amidine" patented technology

The invention discloses a novel synthetic method for 5-phenyl tetrazole, which includes the following steps: firstly performing acid neutralization to hydrazine hydrate; then adding mixing solution formed by cyanobenzene, water and ethyl alcohol to generate phenyl aminoguanidine salt; adopting sodium nitrite for diazotization to obtain nitrine amidine under the acidic condition; obtaining 5-phenyl tetrazole crude product through closed loop under the alkaline condition; obtaining 5-phenyl tetrazole acceptable product through adopting ethyl alcohol for refining. The method has the advantages of simple technology, simplicity in operation and high product yield.

The invention provides a CO2 response type alkyl amidine surfactant with clay stabilization and oil displacement functions and a method for applying the CO2 response type alkyl amidine surfactant to clay stabilization and oil displacement. The surfactant is protonated after contacting with CO2 and is converted into cations from a nonionic form in situ, the generated cations can be efficiently adsorbed on the surface of clay, and the clay is stabilized by inhibiting hydration expansion and changing wettability; the protonated product has excellent foaming performance and emulsifying capacity, so that the protonated product shows good oil washing and oil displacement performance. The surfactant provided by the invention is suitable for low-permeability tight reservoirs of CO2 storage and CO2 oil displacement, and can synchronously solve the two problems of clay expansion damage and improvement of the crude oil recovery rate.

This invention discloses a method for synthesizing acetate-promoted amidine cobalt complexes. Specifically, when an N,N'-dialkyl-substituted amidine alkali metal salt reacts with a cobalt precursor, acetate is added as a promoter. The chelating effect of acetate regulates the reaction activity and selectivity, enabling the efficient preparation of amidine cobalt compounds. The reaction yield can reach up to 95%, with a product purity >98%. This invention features readily available raw materials, simple operation, mild reaction conditions, good selectivity for the target product, high synthesis efficiency, and convenient post-processing, making it promising for industrial applications.

The carbon dioxide responsive liquid crystal film containing amidine compound is formed by a cholesteric liquid crystal polymer capable of reflecting visible light and an amidine compound, and the film is prepared from the amidine compound, cholesteric liquid crystal monomer, crosslinking agent, chiral dopant, photoinitiator and porogen, and the amidine group in the amidine compound reacts with carbon dioxide to increase the hydrophilicity of the polymer network, and when water penetrates into the film, the light reflected by the film is red-shifted and the color is changed accordingly. The carbon dioxide responsive liquid crystal film prepared by the application has stable color change effect, obvious response effect, is easier to distinguish, is still reversible after multiple cycles, and the performance of the film is maintained well after multiple cycles.

The invention provides a polyether prepared by polymerizing an alkylene oxide in the presence of a starter, an aluminum compound having at least one hydrocarbyl substituent, and a cyclic amidine. The amount of the phosphorus-nitrogen base present is in a small molar ratio to the amount of the starter. The presence of such a small amount of the cyclic amidine greatly increases the catalytic activity of the system compared to the use of the aluminum compound alone. The product polyether has a small amount of unsaturated polyether impurities and has little or no undesirable high molecular weight fractions. The proportion of primary hydroxyl groups of the propylene oxide polymer is low.

The objective is to provide a shortened manufacturing method for (alkylsulfonyl)pyridine-N-substituted amidine derivatives or (alkylsulfonyl)pyridine-diazole heterocyclic derivatives that have pest control properties. [Solution] By reacting an (alkylsulfonyl)pyridine-amidine derivative with R6-O-NH2, the corresponding (alkylsulfonyl)pyridine-N-substituted amidine derivative can be directly produced. Furthermore, this manufacturing process provides a shortened manufacturing method for (alkylsulfonyl)pyridine-diazole heterocyclic derivatives.

This invention discloses a method for synthesizing monosubstituted sulfonylamidinium compounds. In an air atmosphere, using commercially available primary sulfonamides and nitriles as substrates, inexpensive trifluoromethanesulfonic anhydride as a catalyst, and trifluorotoluene as a solvent, the product can be efficiently obtained. Compared with existing technologies, this method has the following advantages: inexpensive and readily available reactants; no need for cumbersome synthesis methods; simple reaction system; high atom economy with 100% atom utilization; broad substrate range, compatible with various functional groups; and simple operation.

The invention discloses a synthesis method of a trifluoromethanesulfonate radical promoted amidino nickel complex. The preparation method comprises the following steps: reacting N, N '-dialkyl substituted amidino alkali metal salt with a nickel precursor, adding trifluoromethanesulfonate as an accelerant, and regulating the reaction rate and selectivity by utilizing the coordination effect of trifluoromethanesulfonate so as to efficiently prepare the amidino nickel complex. In the process, an ether compound is used as a solvent, the reaction is carried out at 0-70 DEG C for 1-48 hours, the reaction yield can reach 90% at most, and the product purity is gt; and 98%. The method has the characteristics of easily available raw materials, simplicity and convenience in operation, mild reaction conditions, good target product selectivity, high synthesis efficiency, convenience in post-treatment and the like, and has industrial application prospects.

The present disclosure provides compositions and methods for sample processing, particularly for oligonucleotide analysis e.g. analysis of formulated nucleic acid drugs. A composition for pretreating at least one target nucleic acid in a biological mixture provided herein includes a chaotropic agent selected from a substituted guanidine, a substituted amidine, a substituted quaternary amine, or a combination thereof, an optional protease, and / or an optional disulfide-reducing agent. Methods of analyzing at least one target nucleic acid in a biological mixture is also provided herein. Furthermore, the present disclosure provides methods for quantifying at least one target cationic lipid interacting with a nucleic acid.

The invention discloses a porphyrinyl hydrogen bond organic framework cascade catalytic material for in-situ encapsulation of biological enzyme and a preparation method thereof. According to the cascade catalytic material, amidine salt, bio-enzyme and porphyrin iron carboxylate are subjected to a one-pot reaction by using a charge-assisted hydrogen bond strategy, so that the porphyrinyl hydrogen bond organic framework (GOx-Fe-HOF) nano catalytic material for in-situ encapsulation of the bio-enzyme is synthesized in a water phase at room temperature, and a Fe-HOF nano enzyme-immobilized GOx enzyme synergistic cascade reactor can be formed; the method is applied to glucose analysis and detection. The cascade catalytic material integrates Fe-HOF room temperature water phase synthesis, biological enzyme in-situ packaging and multi-enzyme cascade analysis, has the advantages of high stability and capability of tolerating harsh environmental conditions, and can be used for preparation of bionic HOF nano functional materials and multi-enzyme cascade reactors and medical and biochemical detection and analysis.

The present inventive concept provides a method for forming a thin film of a perovskite compound, the method comprising: a step for depositing a perovskite compound by reacting at least one compound selected from amine-based compounds and amidine-based compounds, an organometallic compound including a divalent cation, and at least one halogenated hydrogen; and a step for removing impurities present in the perovskite compound.

The application discloses a 4-pentene imino sulfone-based amidine series compound and a preparation method and application thereof. The method uses commercially available imino sulfone and N-allyl alkynyl sulfonamide as reaction substrates, and uses a cheap palladium salt as a catalyst, so that the 4-pentene imino sulfone-based amidine series compound is efficiently synthesized and prepared under a catalytic condition without strict water and oxygen, and at room temperature. The product obtained by the application has novel structure, high production efficiency, wide compatibility of substrate functional groups, conforms to green reaction characteristics, is suitable for large-scale preparation, has excellent industrial application prospect, is an environment-friendly green chemical technology, has wide compatibility of substrate functional groups, conforms to green reaction characteristics, is suitable for large-scale preparation, and is also an environment-friendly green chemical synthesis drug technology.

The present technology relates to an ionic plastic crystal comprising at least one delocalized anion paired with at least one an organic guanidine, amidine or phosphazene organic superbase-derived cation for use in electrochemical applications, particularly in electrochemical accumulators such as batteries, electrochromic devices, and supercapacitors. The present technology also relates to an ionic plastic crystal composition, an ionic plastic crystal-based solid electrolyte composition, an ionic plastic crystal-based solid electrolyte, an electrode material comprising the ionic plastic crystal or the ionic plastic crystal composition. Their uses in electrochemical cells and electrochemical accumulators as well as their processes of manufacturing and an NHO-stabilized intermediary ion-neutral complex are also described.

A clear coating composition includes a hydroxyl group-containing acrylic resin (a), a hydroxyl group-containing polyester resin (b), a polyol compound (c) other than the hydroxyl group-containing acrylic resin (a) and the hydroxyl group-containing polyester resin (b), a polyisocyanate compound (d), organic dispersed particles (e), a cellulose derivative (f), and an organic amine catalyst (g) having an amidine group. The hydroxyl group-containing acrylic resin (a) has a hydroxyl value of 90 mg KOH / g to 190 mg KOH / g, a weight average molecular weight of 4000 to 6000, and a glass transition temperature of 15°C to 100°C. The polyol compound (c) has a hydroxyl value of more than 200 mg KOH / g to 1000 mg KOH / g and a molecular weight of 100 to 1000. The cellulose derivative (f) contains at least one selected from the group consisting of cellulose ethers and cellulose esters and has a solids concentration of 50 mass% or more.

A charging roll for an electrophotographic apparatus includes a shaft body and an elastic body layer formed on an outer circumferential surface of the shaft body. The elastic body layer contains (a) to (c) below: (a) a hydrin rubber with a chlorine content of 14% or more and 19% or less; (b) an ionic conductive agent; and (c) a salt of a cyclic amidine compound. The hydrin rubber includes a crosslinking agent which is a sulfur crosslinking agent or a peroxide crosslinking agent.

The invention discloses a cationic lipid compound as well as a preparation method and application thereof, and the cationic lipid compound has the following structural characteristics: 1, the lipid compound has a multi-amino amidino head structure, so that the delivery efficiency of nucleic acid molecules can be improved; 2, the lipid compound has a phenylamidine structure, so that the structural stability of amidino can be improved, and the physical and chemical stability of lipid molecules can be improved; and 3, double biodegradation structures based on amidino and amidino bonds on two sides of a benzene ring in a lipid compound structure can be hydrolyzed and broken into small molecules after nucleic acid molecules are effectively delivered, so that the cell biocompatibility of lipid molecules can be improved, and the in-vivo safety can be improved. In conclusion, the multi-amino amidino cationic lipid molecule has the characteristics of high delivery efficiency, good cell biocompatibility and excellent storage stability, provides more choices for nucleic acid drug delivery, and has important significance for development and application of nucleic acid drugs.

The application provides a method for defluorocyclization reaction of perfluoroalkyl tetrahydronaphthalenone and amidine compound and cobalt-1,3-dicarbonyl complex under the promotion condition of cesium carbonate, and a series of fluorine alkyl substituted furan quinazoline compounds are synthesized. The strategy is free from the dependence on multi-step pre-functionalization and transition metal catalysis in the traditional synthesis path. In the reaction process, six carbon-fluorine bonds at three perfluoroalkyl carbon sites of the polyfluoroalkyl ketone are continuously broken, five carbon-carbon / carbon-nitrogen / carbon-oxygen bonds and two heterocycles are constructed through one-pot method, the accurate synthesis of the fluorine alkyl substituted furan quinazoline compound is realized, and the method has the characteristics of mild condition, good functional group tolerance, simple post-treatment, green step, low pollution and high economic benefit; and the obtained compound shows certain inhibition activity on human malignant melanoma (A-375) cells.

A method for preparing amidines or derivatives thereof includes the step of subjecting N-(amino-alkyl) lactams to dehydration in the presence of a heterogeneous catalyst chosen from a Lewis acid, Lewis acids with Bronsted acid or Bronsted acid components such as cerium oxide catalysts; boron phosphates, cerium, zirconium; other zirconium salts; modified zirconium oxides; and phosphotungstic acid.

A thermally expandable composition includes at least one epoxy-functional polymer, at least one endothermic chemical blowing agent, and at least one curative selected from the group made of a urea, urea derivatives, guanidine derivatives, amidine derivatives, and imidazoles. Further, a baffle and / or a reinforcement element for hollow structures includes the thermally expandable composition, a process manufactures the baffle and / or the reinforcement element, the baffle and / or the reinforcement element is used for sealing, baffling, or reinforcing of a cavity or a hollow structure, and a method seals, baffles and / or reinforces a cavity or hollow structure.

This invention discloses a one-pot method for preparing amidine-lanthanum complexes. Specifically, the lanthanum salt first reacts with an ether compound; the product, without separation, is then directly reacted with an N,N'-dialkyl-substituted amidine alkali metal salt to prepare the amidine-lanthanum complex in a one-pot process. The reaction yield can reach up to 90%, and the product purity is >98%. This invention features readily available raw materials, simple operation, mild reaction conditions, good selectivity for the target product, high synthesis efficiency, and convenient post-processing, making it promising for industrial applications.

A method for forming a perovskite compound thin film is disclosed, comprising reacting the following reactants: i) at least one compound selected from the group consisting of amine compounds, amine iodides, amine bromides, amine chlorides, amidine compounds, amidine iodides, amidine bromides, and amidine chlorides; ii) an organometallic compound containing a divalent cation represented by R1(CH3)4 or R1(CH2H5)4 (wherein “R1” includes metals selected from the group consisting of Pb, Sn, Ge, Sb, Bi, and Ba); and iii) at least one hydrohalide selected from the group consisting of HI, HBr, Hf, and HCl.

The invention discloses a metal amidino precursor and a preparation method thereof, and belongs to the technical field of semiconductor materials. According to the preparation method, an alkyl metal complex or metal hydride reacts with alkyl diimine to prepare N, N '-dialkyl amidino salt (M0L), and then the N, N'-dialkyl amidino salt (M0L) reacts with metal chloride (MClx) to prepare the metal amidino complex.The MLX is prepared through a one-pot method, purification is not needed in the middle process, the reaction is simple, and the problem that the synthesis process of the metal amidino complex is complex is solved.

A fuel composition is disclosed. The composition comprises a hydrocarbon fuel, including gasoline or diesel, and one or more guanidine-based or amidine-based surfactants, or acceptable salts thereof.

Solid adsorbents based on amidine-containing aliphatic amine polymers with resistance to oxidative damage in air and water at elevated temperatures compared to the prior art is disclosed. The solid adsorbent exhibits a high porosity and reactivity for the adsorption of carbon dioxide (CO2) from ambient air and does not require a porous substrate material such as porous silica to generate said porosity and reactivity to or with CO2. The material is particularly useful as a CO2 adsorbent for Direct Air Capture (DAC) applications.

The application belongs to the field of organic synthesis, and particularly relates to a synthesis method of diaryl acetylene. A toluene compound shown in formula 1 and a methyl benzoate compound shown in formula 2 are mixed with an organic solvent (toluene or dimethyl tetrahydrofuran) in the presence of a strong base (lithium bis(trimethylsilyl)amide), a cesium salt additive (cesium fluoride), an amidine additive (DBU) and an activating agent (Nf-F), and then reacted to synthesize the diaryl acetylene shown in formula 3. The raw material used in the application is simple and easy to obtain, a one-pot synthesis method of the diaryl acetylene is constructed, and the application has the advantages of simple synthesis method, economy, environmental protection and wide application range.

The application discloses a method for preparing a pyrimidine derivative by catalyzing lignin conversion through a rhodium-based catalyst. The method takes real lignin as a substrate, takes amidine hydrochloride and a primary alcohol as reaction raw materials, and utilizes the rhodium-based catalyst to prepare the pyrimidine derivative in an air atmosphere through a one-pot two-step method under alkaline conditions. The method for preparing the pyrimidine derivative from the real lignin is realized, and the method has the advantages of simplicity, high product selectivity, mild reaction conditions and the like.

The application belongs to the technical field of organic conjugated compounds, and particularly relates to a water-soluble arylene-acetylene luminophore containing amidine urea groups, a preparation method and application thereof. The preparation method of the water-soluble arylene-acetylene luminophore containing amidine urea groups comprises the following steps: (1) under a nitrogen atmosphere, reacting guanidino monomers, acetylenic compounds, a catalyst and a mixed solvent to obtain a reaction solution; (2) extracting the reaction solution, drying an organic phase, and performing rotary evaporation under reduced pressure to obtain a crude product, and then separating and purifying the crude product to obtain an amidine urea group arylene-acetylene compound; (3) mixing the amidine urea group arylene-acetylene compound with dichloromethane, adding trifluoroacetic acid, stirring, performing rotary evaporation under reduced pressure, washing with an organic solvent, and drying to obtain the water-soluble arylene-acetylene luminophore containing amidine urea groups. The water-soluble arylene-acetylene luminophore containing amidine urea groups obtained by the application has excellent activity, good water solubility, stable chemical properties, high sensitivity and strong selectivity.

This invention discloses a method for preparing sulfur-containing polymers based on isomerization-driven irreversible ring-opening polymerization. The method includes: in an organic solvent, in the presence of a main catalyst, carrying out a polymerization reaction of one or more monomers; wherein the main catalyst is an anionic or cationic catalyst; the anionic catalyst is a phosphononitrile base, guanidine organic base, amidine organic base, N-heterocyclic carbene organic base, N-heterocyclic olefin organic base, carboxylate, or thiocarboxylate; the cationic catalyst is a zwitterionic catalyst, a neutral Lewis acid catalyst, or a protic acid (ester) catalyst; and the monomer is a five-membered ring skeleton compound as shown in Formula I. This method provides convenience for the industrial production of environmentally friendly sulfur-containing polymer materials. The synthesized sulfur-containing polymer has advantages such as high molecular weight, wide-range tunable physical properties, and excellent degradability, and can be used as plastics, rubber, elastomers, fibers, and other products.

The application belongs to the technical field of medicine, and discloses a kind of amidine compound and its preparation method and application in treating bacterial infection, specifically discloses a kind of amidine compound and its pharmaceutically acceptable salt and preparation method and application in treating bacterial infection as shown in the following general formula (I).The amidine compound of the application is used in the preparation of products for enhancing the activity of other antibiotics.The antibiotics include macrolide drugs, pleuromutilin drugs, quinolone drugs, rifamycin drugs, dihydrofolate reductase inhibitor drugs, oxazolidinone drugs, lincosamide drugs, capreomycin drugs, mupirocin drugs and fusidic acid drugs.

The present invention involves: a dehydration step for adding (B) an amidine structure-containing compound and (C) an alkoxysilane-containing dehydration agent to a system including (A) an organic polymer that has a reactive silicon group represented by -SiX3 (X represents a hydroxy group or a hydrolyzable group), and stirring same at 10°C-90°C under a pressure at which the alkoxysilane-containing dehydration agent (C) does not substantially volatilize; a devolatilization step for devolatilizing a volatile component included in the system including the organic polymer (A) after the dehydration step under reduced pressure; and a mixing step for mixing (C') an alkoxysilane-containing dehydration agent with the system including the organic polymer (A) after the devolatilization step. The amount of the alkoxysilane-containing dehydration agent (C) added in the dehydration step is set such that the total amount in moles of alkoxy groups directly bonded to silicon atoms contained in the alkoxysilane-containing dehydration agent (C) is 100%-300% by mol with respect to 100% by mol of the moisture content of the system including the organic polymer (A) before the dehydration step.