3121 results about "Nitrite" patented technology

The invention provides a preparation method of ticagrelor, belonging to the technical field of medicine manufacturing. According to the method, a compound VII is taken as a raw material, and the method comprises the steps of: carrying out a nucleophilic substitution reaction on the raw material to obtain a compound VI; hydrogenating the VI, removing carbamazepine (Cbz) protection to obtain a compound V; carrying out a reaction on the V and 4, 6-dichloro-2-(allyl sulfide)-5-amio-pyrimidine to obtain a compound IV; carrying out a reaction on the IV and nitrite of alkali metal to obtain a compound III; carrying out a reaction on the III and (1R, 2S)-2-(3, 4-difluoro phenyl) cyclopropylamine to obtain a compound II; and finally, removing protecting group of the II to obtain a compound I.

PCT No. PCT/JP97/00578 Sec. 371 Date Aug. 11, 1998 Sec. 102(e) Date Aug. 11, 1998 PCT Filed Feb. 27, 1997 PCT Pub. No. WO97/32030 PCT Pub. Date Sep. 4, 1997A process for preparing alpha -hydroxy acids represented by the general formula (II): RCH(OH)COOH (wherein R represents a hydrogen atom, an optionally substituted C1-C6 alkyl group, an optionally substituted C2-C6 alkenyl group, an optionally substituted C1-C6 alkoxy group, an optionally substituted aryl group, an optionally substituted aryloxy group, or an optionally substituted heterocyclic group) by allowing a microorganism to act on alpha -hydroxy nitriles (I): RCH(OH)CN (wherein R is as defined above) to hydrolyze and convert the alpha -hydroxy nitrites to alpha -hydroxy acids (II), wherein the alpha -hydroxy acids (II) are produced and accumulated in an aqueous solvent by a microorganism having the concentration resistance to the alpha -hydroxy nitrites (I) and/or alpha -hydroxy acids (II) and durability preferably in the presence of a cyanide, and harvested. According to this process, the use of the microorganism having the concentration resistance to the alpha -hydroxy nitriles (I) and/or alpha -hydroxy acids (II) and durability high enough to permit the activity to persist for a long period of time enables alpha -hydroxy acids (II) to be accumulated in high concentrations and cell bodies to be repeatedly used, and hence enables alpha -hydroxy acids (II) to be efficiently prepared. The addition of a cyanide to the reaction system results in more efficient preparation of alpha -hydroxy acids (II).

Disclosed is an emulsifying metal-cutting-fluid composition comprising base oil or oily agent, mixed alcohol-amine, anionic surfactant, nonionic surfactant, antirust agent, copper alloy corrosion inhibitor, preservative and the like. The invention has a strong general usability, suitable for metal processing, particularly aluminum alloy metal processing with advantages of excellent lubricity, corrosion resistance, a low cost and being free of toxic or harmful substances such as nitrites and phenols, so as to keep the environment and operators away from harmfulness.

Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.

A lithium ion electrochemical cell having high charge/discharge capacity, long cycle life and exhibiting a reduced first cycle irreversible capacity, is described. The stated benefits are realized by the addition of at least one nitrite additive to an electrolyte comprising an alkali metal salt dissolved in a solvent mixture that includes ethylene carbonate, dimethyl carbonate, ethylmethyl carbonate and diethyl carbonate. The preferred additive is an alkyl nitrite compound.

The positive electrode active material of a positive electrode includes a sodium-containing transition metal oxide (Na_aLi_bM_xO_2±α). The M includes at least two of manganese (Mn), iron (Fe), cobalt (Co), and nickel (Ni). For a negative electrode, a sodium metal or a metal that forms an alloy with sodium is used. A non-aqueous electrolyte produced by dissolving an electrolytic salt (sodium salt) in a non-aqueous solvent is used. Examples of the non-aqueous solvent may include a cyclic carbonate, a chain carbonate, esters, cyclic ethers, chain ethers, nitrites, amides and a combination thereof.

The invention discloses a concrete early-strength agent, which is characterized in comprising the following components according to weight percentage: inorganic salt early-strength component 35-55 percent, organic early-strength component 5-10 percent, water reducing component 15-25 percent, wherein the inorganic salt early-strength component is prepared by at least two among sulfate, carbonate, nitrate, and nitrite; the organic early-strength component selects any one among calcium formate, sodium acetate, calcium oxalate, triethanolamine, tri-iso-propanolamine and carbamide; the water reducing component selects one among naphthalenesulfuric acid type, melamine type and polycarboxylate type. The invention makes the concrete be coagulated and hardened rapidly under the condition of low temperature, so that the early strength of the concrete is greatly improved as well as later strength is ensured.

The invention relates to a lactobacillus plantarum strain having functions of effectively degrading nitrite and strongly producing acid and an application of the lactobacillus plantarum strain, and belongs to the technical field of bioengineering. The lactobacillus plantarum strain having the functions of effectively degrading nitrite and strongly producing acid is selected from conventional fermented pickled vegetables in Shenyang peasant families, wherein the strain is named FM-LP1-1, identified to be lactobacillus plantarum, and the strain is preserved in China General Microbiological Culture Collection Center with the preservation number of CGMCC No. 9488 on August 4, 2014. By taking FM-LP1-1 as a fermenting agent for fermenting vegetables, the content of nitrate in the fermented vegetable products is effectively reduced, the fermenting duration of the vegetables is shortened and the fermenting flavor of the vegetables is enhanced; and the strain disclosed by the invention is broad in application prospect.

The invention provides a solid catalyst component for the polymeriztion of olefins comprising a Ti compound and an electron donor (ED) selected from alcohol, ketones, amines, amides, nitrites, alkoxysilanes, aliphatic ethers, and esters of aliphatic carboxylic acids supported on Mg dichloride in which the ED/Ti molar ratio ranges from 1.5 to 3.5 and the Mg/Ti molar ratio is higher than 5.5. The invention also provides a catalyst for the polymerization of olefins using the solid catalyst component and a process for the (co)polymerization of olefins CH2=CHR.

The invention provides a smoke catalysis and oxidation denitration process which takes a catalyst using TiO2 or ZrO2-TiO2 as a carrier and Co as active ingredient, uses the oxygen contained in the smoke to oxidate the NO as NO2 which is easy to be dissolved in water, utilizes the alkali solution to absorb the NO2 and remove the NOx. The process of the invention has high denitration efficiency and low cost, can selectively recover the nitrite in the denitration outgrowth and realize the resource utilization of the outcome after controlling the content of the NO2 in the oxidated smoke.

The invention relates to a phosphorus-free metal cleaning agent comprising the components of, by weight, 2-20% of a cleaning aid, 1-20% of a surfactant, 1-10% of a chelating agent, 1-20% of an emulsifier, 1-10% of an antirust agent, 0.2-4% of a copper alloy corrosion inhibitor, 1-10% of a penetration agent, 1-6% of a solubilizing agent, 0.1-0.6% of a defoaming agent, and balance of water. The cleaning agent provided by the invention has excellent cleaning capacity, long rust proof period, low foam, long service life, and the like. The cleaning agent is suitable for ferrous metal and non-ferrous metal processing industries. The agent has the advantages of no volatilization, no irritation, no toxic or harmful substance such as nitrite, no damage to health, and no environment pollution.

A process and apparatus for synthesizing a nanopowder is presented. In particular, a process for the synthesis of nanopowders of various materials such as metals, alloys, ceramics and composites by induction plasma technology, using organometallic compounds, chlorides, bromides, fluorides, iodides, nitrites, nitrates, oxalates and carbonates as precursors is disclosed. The process comprises feeding a reactant material into a plasma torch in which is generated a plasma flow having a temperature sufficiently high to yield a superheated vapour of the material; transporting said vapour by means of the plasma flow into a quenching zone; injecting a cold quench gas into the plasma flow in the quenching zone to form a renewable gaseous cold front; and forming a nanopowder at the interface between the renewable gaseous cold front and the plasma flow.

A method for stabilizing collagenous eye tissues by nitrite and nitroalcohol treatment. The topical stiffening agent contains sodium nitrite or a nitroalcohol in a buffered balanced salt solution and can be applied to the surface of the eye on a daily basis for a prolonged period. Application of the solution results in progressive stabilization of the corneal and scleral tissues through non-enzymatic cross-linking of collagen fibers. The compounds can penetrate into the corneal stroma without the need to remove the corneal epithelium. In addition, ultraviolet light is not needed to activate the cross-linking process. The resulting stabilization of corneal and scleral tissues can prevent future alterations in corneal curvature and has utility in diseases such as keratoconus, keratectasia, progressive myopia, and glaucoma.

The invention relates to a dry powder ready-to-use starter and a preparation method for the starter. The dry powder ready-to-use starter consists of the compound lactic acid powder made from lactobacillus plantarum 550 and lactobacillus buchneri 225, the nutritional agents promoting the lactobasillus to grow or perfume selectively added. The lactobacillus plantarum powder and the lactobacillus buchneri powder are prepared by liquefying, saccharifying, inoculating, fermenting, centrifugating, spraying and drying the corn powder. The compound lactobacillus powder is prepared by mixing the lactobacillus plantarum powder with the lactobacillus buchneri powder by a weight ratio of the lactobacillus plantarum powder to the lactobacillus buchneri powder ranging from 65 to 30: 70 to 35. When the infusing is carried out, the compound lactobacillus powder is dissolved into the fermentation broth by the cold boiling water and the salt, the sugar, the peptone and the perfume are added to the fermentation broth to make the pickle. The pickle products can be obtained by infusing the fresh vegetables in the pickle for 18 to 24 hours. With easy storage, convenient carrier and use, quick and simple preparation, the starter mannufactures the pickle which not only reaches the flavor and quality of the traditional products, but also effectively lowers the formation of the nitrites.

The invention discloses a denitrifying strain with nitrifying function, a strain-containing water body improver of multiple active microorganisms and a preparation method of the water body improver, belonging to the technical fields of aquaculture and water body improvement. The strain disclosed by the invention is conserved in the China center for type culture collection (CCTCC), the CCTCC NO isM2011443; and the water body improver of the active microorganisms which is based on the strain comprises multiple strains such as Bacillus subtilis, Bacillus licheniformis, Bacillus pumilus, Bacillus cereus, Bacillus megaterium, Rhodopeudomonas palustris, Arthrobacter globiformis, Rhodotorula rubra and Lactobacillus plantarum. The strain is used to perform liquid fermentation and obtain fermentation liquor of which number of live bacteria is 0.5-3*10<10>cfu/mL, bacterial powder of which the number of live bacteria is 0.2-2*10<12>cfu/mL is further prepared; and the bacterial powder is used along with a diluent to prepare a liquid or powdery water body improver, wherein the effective live bacteria of the water body improver is 0.1-3*10<10>cfu/mL(or cfu/g). The water body improver has the function of reducing the contents of ammonia nitrogen, nitrites and nitrates in the culture water body; and the water body improver is suitable for different culture water bodies and has the function of improving the water quality.

The invention discloses a wet-method smoke denitration process used for recovering nitrite, comprising the steps as follows: hydrogen peroxide or ozone is taken as oxidant; the oxidant is uniformly sprayed into smoke disposed by pre-dedusting and desulfurizing so as to carry out gas oxidation reaction and lead the NO in the smoke to be oxidated as NO2; subsequently, alkali liquid is taken as absorbent so as to absorb the mixture of the oxidated NO and NO2 and generate the nitrite; the absorbent is concentrated after absorbing the NO and NO2 and cooled and crystallized; after centrifuging separation, the nitrite crystal is gained. The process of the invention can effectively remove the NOx in the smoke, gains the nitrite with high economic values at the same time, and realizes the resource utilization of denitration outgrowth.

The present invention provides a method for oxidizing a substance (e.g., in a waste stream, drinking water, a paper pulp slurry, or on a surface), which uses free radicals and reactive species generated from multiple oxidants. The method comprises combining peroxynitrite or peroxynitrous acid and at least one additional oxidizing agent for a period of time sufficient to oxidize the substance of interest. The peroxynitrite or peroxynitrous acid preferably is formed by irradiation of nitrate ion and/or nitric acid (e.g., with UV or gamma rays). The yield of free radicals and reactive species, which are the intermediate species that perform the oxidation may be increased by addition of a catalysts, electromagnetic radiation, sonic waves, and/or electrolysis.

An alkali metal, solid cathode, nonaqueous electrochemical cell capable of delivering high current pulses, rapidly recovering its open circuit voltage and having high current capacity, is described. The stated benefits are realized by the addition of at least one nitrite additive to an electrolyte comprising an alkali metal salt dissolved in a mixture of a low viscosity solvent and a high permittivity solvent. A preferred solvent mixture includes propylene carbonate, dimethoxyethane and an alkyl nitrite additive.

The present invention is directed to an unexpected benefit in a lithium cell derived from using a combination of silver vanadium oxide prepared in a temperature range of about 450° C. to about 500° C. activated with a nonaqueous electrolyte having a passivation inhibitor additive selected from a nitrite, a nitrate, a carbonate, a dicarbonate, a phosphonate, a phosphate, a sulfate and hydrogen fluoride, and mixtures thereof. The benefits include additional battery life resulting from a reduction in voltage delay and RDC build-up. A preferred electrolyte is 1M LiAsF6 in a 50:50 mixture, by volume, of PC and DME having dibenzyl carbonate added therein.

The invention discloses a novel mesoporous material for adsorbing tar, phenol and special nitrosamine in tobacco and so on, in mainstream smoke of the tobacco. The mesoporous material with high adsorption property is used as an addition material for filter tips of cigarettes; and the mesoporous material is a mesoporous molecular sieve with a three-dimensional mesh microstructure and monolithic appearance such as SBA-15,or is a SBA-15 mesoporous molecular sieve material which is plated with a liquid film or is modified by metal oxides such as zirconia and is provided with the three-dimensional mesh microstructure and the monolithic appearance. The invention adopts a more convenient and effective method to develop the SBA-15 mesoporous molecular sieve material with the three-dimensional mesh microstructure and the monolithic appearance and modify the surface/a surface layer, has good performance of intercepting environmental toxins such as interception particulate phase matters and phenol in smoke, has the characteristics of saving energy, saving time, and reducing environmental pollution during the preparation, can also reduce cost, and has remarkable economic benefit and social benefit.

The invention relates to a migration-type organic reinforced concrete anti-corrosion admixture which is prepared by mixing organic carboxylic acid and organic amine in the following percentage by weight: 40-80% of the organic carboxylic acid and 20-60% of the organic amine; adding the mixture into water; heating to 60-70 DEG C; and stirring the mixture for reaction for 1-2 hours to obtain the migration-type organic reinforced concrete anti-corrosion admixture. The anti-corrosion admixture does not contain nitrite and inorganic base and can prevent damage on reinforcing steel bar passive films caused by chloride ions, thus preventing corrosion.

Dumbbell-shaped or flower-shaped nanoparticles and a process of forming the same, wherein the process comprises forming a mixture of a nanoparticle with a precursor in a first solvent, wherein the nanoparticle comprises a hydrophobic outer coating; heating the mixture; cooling the mixture to room temperature; modifying the hydrophobic outer coating into a hydrophilic outer coating; precipitating a solid product from the mixture, and dispersing the product in a second solvent. The nanoparticles comprise any of a semiconducting, magnetic, and noble metallic material, wherein the nanoparticles comprise a first portion comprising any of PbSe, PbS, CdSe, CdS, ZnS, Au, Ag, Pd, and Pt, and wherein the precursor comprises any of a cationic, neutral or particulate Au, Ag, Pd, Pt, or transition metal (Fe, Co, Ni) precursors of Fe(CO)₅, Co(CO)₈, Ni(CO)₄ or their analogues. The first and second solvents comprise any of alkanes, arenes, ethers, nitrites, ketones, and chlorinated hydrocarbons.

The invention is polymerizable compositions comprising in one part an organoboron compound capable of forming a free radical generating species and a stabilizing amount of one or more compounds comprising a dihydrocarbyl hydroxyl amine, an alicyclic hydroxyl amine, or a nitrite oxide of a dihydrocarbyl hydroxyl amine or an alicyclic hydroxyl amine, and in the second part one or more compounds capable of free radical polymerization.