350 results about "Phenolic acid" patented technology

The invention discloses bacillus velezensis YB-1652, a biocontrol microbial inoculum and application of the biocontrol microbial inoculum, and aims to solve the technical problem of lack of effective biological control measures for continuous accumulation of peanut phenolic acid autotoxic substances and pathogens in continuous cropping. According to the application, a bacillus velezensis YB-1652 strain is separated and screened from rhizosphere soil of continuous cropping peanuts, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.36152. The strain has the capability of efficiently degrading phenolic acid compounds, relieves continuous cropping obstacles and improves the soil environment; the compound has a relatively strong inhibition effect on southern blight and root rot of peanuts, and the occurrence rate of soil-borne diseases is reduced; meanwhile, peanut growth can be promoted; the bacillus amyloliquefaciens has siderophore, cellulase, beta-glucanase, amylase power and protease production capacity. The YB-1652 strain and the preparation thereof can provide technical support for restoration of peanut continuous cropping obstacles, provide bacterial source guarantee for prevention and treatment of peanut soil-borne diseases, replace or reduce use of chemical pesticides and improve food and ecological environment safety, and have good economic and social benefits.

The invention belongs to the technical field of microorganisms, and particularly relates to pseudomonas monteilii BDLZ-3 and application thereof in relieving continuous cropping obstacles of crops. The invention discloses a strain of pseudomonas monteilii BDLZ-3, the preservation number of which is CGMCC (China General Microbiological Culture Collection Center) No.34349. The pseudomonas monteilii BDLZ-3 is separated and screened from the nature for the first time, phenolic acid autotoxic substances generated in the ginseng continuous cropping obstacle process can be efficiently degraded, the degradation rate of benzoic acid can reach 95.36%, various phenolic acids such as vanillic acid, cinnamic acid, palmitic acid and gallic acid can be effectively degraded, and the degradation spectrum is wide; when the pseudomonas monteilii BDLZ-3 is applied in a field, the content of benzoic acid in soil can be effectively reduced, meanwhile, the occurrence of ginseng root diseases can be controlled to a certain extent, the prevention and treatment effect reaches 41.23%, the growth indexes such as root length and root thickness are remarkably improved, and the yield increasing effect is achieved.

The invention provides a content detection method for a salvia miltiorrhiza medicinal material, a salvia miltiorrhiza clear paste and a musk heart-dredging dropping pill. According to the method, a high performance liquid chromatography method is adopted, octadecylsilane chemically bonded silica is used as a chromatographic column filler, acetonitrile is used as a mobile phase A, 0.02%-0.1% trifluoroacetic acid is used as a mobile phase B, gradient elution is carried out, and rosmarinic acid and salvianolic acid B in the salvia miltiorrhiza medicinal material are synchronously and quantitatively detected. And synchronously and quantitatively detecting tanshinol, protocatechuic aldehyde, caffeic acid, salvianolic acid E, rosmarinic acid, alkannic acid and salvianolic acid B in the salvia miltiorrhiza clear paste, and synchronously and quantitatively detecting tanshinol, protocatechuic aldehyde, caffeic acid, salvianolic acid E, rosmarinic acid, alkannic acid, salvianolic acid B, arenobufagin and bufalin in the musk Tongxin dropping pill. The method is used for monitoring the content of specific components, can also judge the transfer rate in the medicine production process, and facilitates traceability in the production link. In addition, the method is relatively low in equipment requirement and suitable for industrial popularization.

The invention relates to the technical field of cosmetic functional raw material preparation methods, in particular to a plant extract and an extraction method and application thereof. The invention provides a plant extraction method, which comprises the following steps: adding a glycol ether or polyhydric alcohol solvent containing 5-7 carbon atoms into a product containing phenolic acid compound components and lignan compound components, carrying out homogeneous reaction, carrying out heating extraction, and collecting the extract. By adopting a supramolecular technology, phenolic acid compound components can form a supramolecular solvent with glycol ether or polyol solvents containing 5-7 carbon atoms, and the supramolecular solvent is further combined with lignan compound components to form a supramolecular structure, so that the stability of an extracting solution is remarkably enhanced, the specific enrichment of the lignan compound components is realized, and the specific enrichment of the lignan compound components is realized. The problems that an existing extraction technology is poor in stability, poor in formula applicability, not prominent in effect and the like are successfully solved.

The invention discloses streptomyces bulbus as well as a multifunctional fungicide and application thereof. According to the invention, firstly, a strain of Streptomyces tauricus zhanshen-LZ-12 is separated and screened from straw returning soil, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.34456. The invention also discloses a preparation method of the Streptomyces tauricus zhanshen-LZ-12. The strain has the functions of degrading cellulose, decomposing protein, fixing nitrogen, resisting salt, degrading phenolic acid autotoxic substances (benzoic acid, p-hydroxybenzoic acid and cinnamic acid) and the like. Bacterial powder obtained after fermentation of the bacterial strain is uniformly mixed with bacillus bacterial powder to obtain the multifunctional bacterial agent, and when straw returning or composting is carried out, the multifunctional bacterial agent is adopted, straw decomposition can be accelerated, soil ecology can be improved, crop growth can be promoted, and the stress resistance of crops can be enhanced.

The invention relates to the technical field of energetic materials, in particular to a laser response type high-entropy alloy-based initiating explosive material and a preparation method thereof. The initiating explosive material is mainly formed by uniformly loading a heat-sensitive high-energy compound (such as lead stilbeneate or hexa (4-amino-3, 5-dinitropyrazole) copper) on high-entropy alloy nanoparticles containing five or more metal elements, wherein the heat-sensitive high-energy compound is such as lead stilbeneate or hexa (4-amino-3, 5-dinitropyrazole) copper. The preparation method comprises the following steps: mixing acetylacetone metal salt, a surfactant and a reducing agent in an organic solvent, and stirring and reacting at 180-220 DEG C to prepare high-entropy alloy nanoparticles; the nano particles and a high-energy compound are co-dispersed in a mixed solvent containing a dispersing agent, ultrasonic treatment is carried out to form suspension liquid, and freeze drying is carried out to obtain the nano particles. The method is characterized in that the excellent photo-thermal conversion performance of the high-entropy alloy is utilized, under low laser energy irradiation, a high-energy compound can be effectively excited, and stable detonation of secondary charge CL-20 is successfully achieved. According to the invention, the problems of high response threshold and low output energy of the existing laser initiating explosive material are solved.

The invention provides a combined lactobacillus salivarius YS-UR90 and a preparation method of the combined lactobacillus salivarius YS-UR90. The saliva combined lactobacillus provided by the invention can secrete protease and glycosidase, and the HCT and FLS gene expression levels of the saliva combined lactobacillus are high, so that the saliva combined lactobacillus can promote phenolic acid active ingredients to generate biotransformation during fermentation, and the proportion of chlorogenic acid and the like in fermentation liquor is increased. For example, marine fish oligopeptide and casein phosphopeptides are used as a composite nitrogen source, dandelion powder is used as a functional substrate, and a composite fermentation product obtained through fermentation of saliva and lactobacillus has the effect of promoting uric acid excretion and has a certain protection effect on kidney injury. The compound fermentation product has the effect of improving hyperuricemia mainly by inhibiting XOD activity, increasing serum urea nitrogen level, improving defect expression of uric acid synthesis gene HPRT1, inhibiting expression of uric acid reabsorption URAT1 and GLUT9 genes and improving expression of excretion genes OAT1 and ABCG2.

Preparation of cannabinoid formulations containing: Δ9-tetrahydrocannabinol (Δ9-THC), Δ8-tetrahydrocannabinol (Δ8-THC), Δ9-tetrahydrocannabinolic acid (THCa), cannabidiol (CBD), cannabidiolic acid (CBDa), cannabigero (CBG), cannabichromene (CBC) and cannabinol (CBN), either alone or in combinations henceforth known as cannabis, have been created using an emulsification process to encapsulate cannabinoids. The aqueous-based method involves micellular encapsulation of cannabinoids, a method that has been used to increase the bioavailability of poorly permeable, lipophilic drugs. The present invention demonstrates the viability of transdermal delivery with gels and patches for consistent and sustained cannabinoid dosing.

The invention discloses a nanometer emulsion based on a citrus extract and a preparation method of the nanometer emulsion. The nano-emulsion takes citrus pectin as a main chain, gallic acid, ascorbic acid-phosphate and oleic acid are sequentially grafted, the oleic acid is lipophilic, the rest is hydrophilic, and the amphiphilic pectin can form the whitening nano-emulsion which can be stably stored for a long time. The natural citrus extract is used for replacing traditional synthetic components, has the anti-oxidation, whitening and anti-inflammatory effects, can reduce the skin sensitivity risk, and conforms to the green beauty makeup trend; meanwhile, the oil phase is anchored by a hydrophobic block, steric hindrance is formed by a hydrophilic block, the stability of the emulsion is remarkably improved, and the shelf life is prolonged to 24 months; phenolic acid and ascorbic acid contained in the traditional Chinese medicine composition can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanogenesis and reduce release of a proinflammatory factor IL-6; the composition is low in cost, environment-friendly, suitable for the fields of cosmetics and medicines and wide in market prospect.

The present application relates to cannabidiol esters, compositions comprising them and their use in the treatment of a variety of different diseases, disorders and symptoms.

The invention discloses a construction method and application of a specific chromatogram of a Shanhaidan pharmaceutical preparation, and belongs to the technical field of traditional Chinese medicine detection. The method comprises the following steps: preparing a test solution by using a plurality of different batches of Shanhaidan medicinal preparations in combination with high performance liquid chromatography and mass spectrometry technologies; the preparation method comprises the following steps: preparing a single reference substance solution from uridine, tanshinol, daidzin, p-hydroxybenzoic acid, puerarin, caffeic acid, 3 '-hydroxy puerarin, physcion, calycosin-7-O-beta-D-glucoside, stilbene glucoside, rosmarinic acid, alkannic acid, formononin, salvianolic acid B, daidzein and calycosin-7-one; and respectively carrying out high performance liquid chromatography analysis on the test solution and the reference solution to obtain the characteristic chromatogram of the Shanhaidan pharmaceutical preparation. The method is simple and convenient to operate, high in precision, good in reproducibility and accurate and reliable in result. And at least 16 components can be identified at one time under the same chromatographic condition, so that the detection efficiency is remarkably improved, the time and the cost are saved, and the quality of the Shanhaidan pharmaceutical preparation is comprehensively and scientifically evaluated.

The invention discloses application of dikafen phenolic acid and ester derivatives thereof in preparation of medicines for treating pulmonary fibrosis. On an MRC-5 cell model induced by TGF-beta1, the bikafen phenolic acid and the multiple ester derivatives thereof show the activity of inhibiting alpha-SMA and COL1A1 protein expression; on a bleomycin-induced pulmonary fibrosis mouse model, the dimethyl ester derivative of the dikafen phenolic acid shows a good protective effect on experimental animals. Therefore, the dicafen phenolic acid and the ester derivative thereof have good application in the field of preparation of medicines for treating pulmonary fibrosis diseases.

The invention discloses a bacillus velezensis strain and application thereof. The invention discloses bacillus velezensis WLH (bacillus velezensis), and the preservation number of the bacillus velezensis WLH is CCTCC (China Center for Type Culture Collection) NO: M 20251238. The bacillus velezensis WLH is screened from rhizosphere of cucumber, the WLH is a biocontrol bacterium, can inhibit growth of pathogenic bacteria of cucumber root rot and fusarium wilt by degrading phenolic acid in soil and promote growth of cucumber plants, and the strain can relieve autotoxicity caused by the phenolic acid, inhibit the cucumber root rot and fusarium wilt and promote growth of cucumber plants. The promotion of crop growth comprises the capability of producing indoleacetic acid (IAA) and the capability of solubilizing phosphate, the promotion of germination of cucumber seeds under the stress of mixed phenolic acid and pathogenic bacteria, and the promotion of growth of cucumber seedlings under the stress of mixed phenolic acid and pathogenic bacteria. Soil continuous cropping obstacles generated in cucumber planting are effectively relieved, and a new basis is provided for microbial control of continuous cropping obstacles.

The application discloses a method for simultaneously determining phenolic acid and tanshinone components in Danshen injection, and according to the structure and property characteristics of the phenolic acid and tanshinone components, the best mobile phase composition, elution program, flow rate, chromatographic column and mass spectrometry condition are screened through a large number of experiments. Experimental verification shows that the UPLC-TQ-MS / MS method can simultaneously determine 11 different structure and type of phenolic acid and tanshinone component compounds, and the methodological verification shows that the detection method has good precision, repeatability and high accuracy, and has important significance for controlling the quality of Danshen injection and guaranteeing the clinical curative effect.

A probiotic and prebiotic-embedded synbiotic system for targeted delivery and colonization of functions, comprising a probiotic core; an inner layer of protein-polysaccharide / oligosaccharide complex wrapped around the probiotic surface, which acts as both an adhesion promoter, promoting the attachment of probiotics to the intestinal epithelial cells, and as a prebiotic, promoting the growth of probiotics upon release; and an outer layer of a natural emulsifying system on the synbiotic complex, which minimizes water infiltration, thereby effectively embedding and protecting the probiotics. The present synbiotic system is suitable for production in powder form using freeze-drying technology, and is suitable as a dietary supplement or for addition to any food in dry powder form. The system has the ability to bioconvert soy isoflavones and release bioactive phenolic acids from grains to promote body health.

The invention relates to the technical field of forest cultivation, and discloses a carya illinoensis fruit forest variety configuration method which comprises the following steps: configuring a main cultivation variety and a pollination variety in a fruit forest; preparing a pollination synergistic composition; the composition is sprayed at the initial stage of stigma exposure of female flowers of a main cultivated variety. The composition comprises a phenolic acid grafted carboxymethyl chitosan derivative, low methoxyl pectin, a calcium ion cross-linking agent, sugar alcohol chelated boron and spermidine. According to the method, an interfacial film with antioxidant activity is formed on the surface of the stigma by using the grafting modified matrix, so that the stigma browning is effectively inhibited, and the pollination period is prolonged; by constructing a calcium cross-linked low-methoxyl pectin interpenetrating network, an interfacial film is endowed with an intelligent degradation characteristic of enzyme-sensitive response to pollen, and protection at ordinary times and immediate dissolution after touching flowers are realized. According to the method, pollen is captured through static electricity, nutritional factors are released in a targeted mode, the pollination and fertilization efficiency is remarkably improved, the sterility risk in the flowering phase is relieved, and the yield and quality of carya illinoensis are improved.

The invention provides a bacillus aerophilus Sys-Gs-010 strain capable of efficiently degrading benzoic acid in soil, the strain is preserved in the China Center for Type Culture Collection on December 10, 2025, the preservation number is CCTCC NO: M20252819, the preservation number is CCTCC NO: M20252819, the preservation number is CCTCC NO: M20252819, and the preservation number is CCTCC NO: M20252819. The 16S rDNA (ribosomal deoxyribonucleic acid) sequence of the strain is as shown in SEQ ID NO. 1. The bacillus aerosus Sys-Gs-010 strain provided by the invention can efficiently degrade ginseng to produce a main phenolic acid allelochemical-benzoic acid, and the strain is a non-ginseng pathogenic strain, can be applied to preparation of a ginseng allelochemical-benzoic acid degrading bacterial agent, greatly improves continuous cropping obstacles of ginseng, and has a good application prospect in the field of ginseng planting.

The application discloses a use of a pharmaceutical composition of a phenolic acid compound and probiotics, and particularly relates to a combination of chlorogenic acid and lactobacillus reuteri. The combination of chlorogenic acid and lactobacillus reuteri can improve glycolipid metabolic disorder, improve cognitive dysfunction, emotional disorder and delay aging, and can be used for preparing a medicine for treating metabolic disorder combined with neuropsychiatric diseases.

The invention discloses application of selfheal total phenolic acid in preparation of a medicine for improving an insomnia sleep structure. The spica prunellae total phenolic acid can effectively shorten the awakening duration, remarkably prolong the rapid eye movement sleep duration, improve the sleep continuity and the like to prolong the total sleep duration and adjust the sleep structure, so that the autonomous activity state and the learning and exploration ability of a patient are recovered. After the total phenolic acid of prunella vulgaris is used for treating insomnia, the sleep duration is gradually prolonged, and no abstinence reaction is generated.

The invention discloses a process method for optimizing total flavone and total phenolic acid extraction of gendarussa ventricosa based on a multi-index comprehensive scoring method in combination with a response surface method. A single factor experiment is carried out by taking the material-liquid ratio, the extraction temperature, the extraction time and the ethanol concentration as investigation factors, the total flavone content and the total phenolic acid content are taken as response values, the extraction process is optimized through a response surface design test, and the optimal extraction process of the total flavone of the gendarussa vulgaris is obtained: the material-liquid ratio is 1: 30, the extraction temperature is 60 DEG C, the extraction time is 45 minutes, the ethanol concentration is 70%, and the total flavone content is 2.487 + / -0.1332 mg / g; according to the optimal extraction process of the total phenolic acid, the material-liquid ratio is 1: 20, the extraction temperature is 55 DEG C, the extraction time is 40 min, the ethanol concentration is 70%, and the content of the obtained total phenolic acid is 10.625 + / -0.285 mg / g. The process method provided by the invention is stable, feasible, simple and easy to operate, good in repeatability and relatively high in extraction efficiency.

The invention relates to a non-natural cannabinoid synthase comprising at least one amino acid variation as compared to a wild type cannabinoid synthase Δ9-tetrahydrocannabinolic acid synthase (THCAS), comprising three alpha helices (αA, αB and αC) where a disulfide bond is not formed between alpha helix αA and alpha helix αC, wherein the non-natural cannabinoid synthase catalyzes the oxidative cyclization of cannabigerolic acid (CBGA) into a cannabinoid. The invention further relates to a non-natural Δ9-tetrahydrocannabinolic acid synthase (THCAS), a non-natural cannabidiolic acid synthase (CBDAS), and a non-natural cannabichromenic acid synthase (CBCAS) comprising at least one amino acid variation as compared to a wild type THCAS, CBDAS, or CBCAS, respectively, comprising three alpha helices (αA, αB and αC) and wherein a disulfide bond is not formed between alpha helix αA and alpha helix αC. The invention also relates to a nucleic acid, expression construct, and engineered cell for making the non-natural THCAS, CBDAS, and / or CBCAS. Also provided are compositions comprising the non-natural THCAS, CBDAS, and / or CBCAS; isolated non-natural THCAS, CBDAS, and / or CBCAS enzymes; methods of making the isolated enzymes; cell extracts comprising cannabinoids; and methods of making cannabinoids.

The application discloses a ZIF drug-loaded nanomaterial, a preparation method and application thereof, and relates to the technical field of pesticide chemistry. A phenolic acid regulator is used for functional modification in the preparation process of ZIF-8 to form a hierarchical porous structure, which is beneficial to improving the drug loading performance of ZIF-8, effectively controlling the release of a pesticide after loading the pesticide, prolonging the persistence of the pesticide, improving the utilization rate of the pesticide, and reducing the amount of the pesticide.

The invention relates to the technical field of biology, in particular to a tobacco Nt4CL9 gene and application thereof. According to the application, tobacco Nt4CL9 is knocked out, and compared with a wild type, the cold stress tolerance of the knocked-out mutant strain is improved, the content of flavonoid substance rutin is obviously increased, and phenolic acid substances are increased; potential support is provided for improvement of tobacco cold stress capacity and tobacco quality, and the method has important practical value in genetic improvement of tobacco important characters and basic research of botany.

The invention discloses application of cynarin in preparation of a medicine for resisting respiratory syncytial virus. The cynarin is polyphenolic acid cynarin, and the respiratory syncytial virus is an RSV-A2 strain; the compound can effectively inhibit replication of respiratory syncytial viruses, is a monomer component of natural medicinal plants, is clear in structure, stable in chemical property, easy in quality control and free of obvious toxic and side effects, can effectively resist inflammation while serving as an active component of a natural small-molecule antiviral drug, and has a broad application prospect. Viral lung inflammatory infiltration and lung injury caused by the respiratory syncytial virus are relieved.

The invention provides a method for simultaneously detecting various phenolic acids and flavonoid active substances in perilla frutescens, which is characterized in that perilla leaves, stems and seeds are taken as detection objects, an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS / MS) technology is adopted, a mixed reference substance solution and a to-be-detected sample solution are prepared, chromatography-mass spectrometry detection parameters are optimized, and the content of various phenolic acids and flavonoid active substances in the perilla frutescens is determined. 15 active substances can be accurately quantified at the same time; the method has the advantages that the pretreatment is simple and convenient, the analysis time is only 10 minutes, the detection sensitivity is high, the detection limit is as low as 0.002 g / L, the linear relation is good, R2 is greater than or equal to 0.9987, the precision, the accuracy and the stability all meet the detection standard, and the detection range covers 1-5000 g / L. The method provides reliable technical support for quality evaluation, product control and standardized production of perilla frutescens, is suitable for detection of perilla frutescens related products, and promotes industrial development of medicinal and edible substances.

The present invention discloses a method for screening effective substances of traditional Chinese medicine based on a 6-dimensional spider web model, belonging to the field of medical technology. Based on the results of UHPLC analysis, the present invention uses danshensu, chlorogenic acid, procyanidin B2, epicatechin, hyperoside, isoquercetin, rosmarinic acid, lithospermic acid, salvianolic acid B, salvianolic acid A, dihydrotanshinone I, tanshinone I, cryptotanshinone, tanshinone IIA, oleanolic acid, and ursolic acid as the "specific" candidate effective ingredients of the Danshen-Hawthorn medicinal pair. Based on the data of the candidate effective ingredients in six dimensions, namely, effectiveness dimension, compatibility environment dimension, transmission and traceability dimension, content measurability dimension, network pharmacology degree value dimension, and molecular docking target binding activity dimension, a "spider web" model is constructed to obtain the key effective substances of the Danshen-Hawthorn medicinal pair. The present invention provides theoretical support for revealing the compatibility theory of the Danshen-Hawthorn medicinal pair, formulating its quality evaluation standards, and clinical application of the Danshen-Hawthorn medicinal pair.

In the process of producing indigo naturalis by taking strobilanthes cusia as a raw material, a very unpleasant smell is generated, a large amount of alkaline wastewater is discharged, and serious environmental pollution is caused. Therefore, development of a more environment-friendly production process and a higher value-added strobilanthes cusia extract is extremely urgent. The invention innovatively provides a green and efficient production process, namely integrally producing the indigo strobilanthes extract and the phenolic acid extract with higher additional values through endogenous enzymatic conversion coupled membrane separation and freeze drying technologies. Through an endogenous enzyme conversion process, the indigo extract with indigo content 20 times and indirubin content 1.8 times higher than that of traditional indigo can be prepared within one day. The phenolic acid extract is recovered from the indigo extract production wastewater by adopting membrane separation and freeze drying processes, and meanwhile, zero discharge of the wastewater can be realized. The prepared indigo extract shows a more excellent dyeing effect on pure cotton poplin than an Indian natural indigo extract. In addition, the prepared phenolic acid extract shows excellent inhibitory activity (IC50 = 32 [mu] g / mL) on staphylococcus aureus, and the wound healing rate of mice exceeds 98%. The method lays a foundation for high-valued and comprehensive utilization of strobilanthes cusia resources, and is of great significance to extension and sustainable and healthy development of a strobilanthes cusia industrial chain.

The present application belongs to the technical field of biological medicine, and particularly relates to a pharmaceutical composition for treating pulmonary fibrosis and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 12-18 parts of Astragalus membranaceus, 6-12 parts of Ophiopogon japonicus, 4-10 parts of Poria cocos, 1-3 parts of Radix Glycyrrhizae, 10-16 parts of Salvia miltiorrhiza, 6-12 parts of Scutellaria baicalensis, 4-10 parts of Morus alba, 2-6 parts of Pericarpium Citri Reticulatae Viride, 1-4 parts of Sophora flavescens and 1-4 parts of Fritillaria cirrhosa. The present application is a three-phase and fixed-ratio compound of polysaccharides, phenolic acids and flavonoids. The polysaccharides are obtained by water extraction and alcohol precipitation, and are used as a mucosal retention adhesion carrier. The phenolic acids and flavonoids are extracted by low-degree ethanol refluxing, so as to ensure the structural integrity and maintain stability. The alkaloids are extracted by ethanol and then mildly salified, so as to reduce irritation and adsorption loss. The polysaccharides are then subjected to selective light fermentation to build a slightly acidic environment. In the compounding process, a buffer system is used to adjust pH, and cyclodextrin is used to stably bind the components. The three phases synergistically intervene in oxidation-inflammation-fibrosis.

The invention discloses high-temperature-resistant coated paper and a preparation method thereof, and belongs to the technical field of coated paper. The PE coated paper is prepared from raw materials including PBAT, PLA, a chain extender, modified montmorillonite, polyvinyl acetate, a slipping agent, an antistatic agent and a hindered phenol antioxidant through the steps of melt blending, extrusion granulation, PE coated compounding and the like. Wherein the modified montmorillonite is prepared by reacting specific phenolic acid with tertiary amine in a mixed solvent to generate a grafted compound and compounding the grafted compound with montmorillonite. Compared with the prior art, the coated paper has the advantages of good thermal stability, low wear-resistant loss, simple preparation process and easily available raw materials, is suitable for high-temperature or high-frequency friction use scenes, and has a good application prospect.

This invention provides a phenolic acid-modified attapulgite composite sunscreen agent, its preparation method, and applications, as well as a Pickering sunscreen lotion, belonging to the field of cosmetic technology. The method of this invention includes acid treatment of attapulgite, surfactant modification, loading of phenolic acid biomolecules, and hydrophobic modification. Using modified attapulgite as a carrier, this invention loads phenolic acid biomolecules through electrostatic adsorption to construct a composite synergistic system, and further modifies the surface with hydrophobicity to obtain a composite sunscreen agent with high stability and excellent sun protection performance. The sunscreen agent prepared by this invention combines physical shielding and biological protection functions, exhibiting excellent UV absorption capacity, good dispersibility, skin compatibility, and a pleasant feel on the skin. It solves the problems of nanoparticle aggregation, whitening, and poor photostability in existing sunscreen products, making it suitable for the cosmetic sunscreen field. It can achieve broad-spectrum UVA / UVB protection, antioxidant properties, and soothing repair, showing broad application prospects.