176 results about "Skin elasticity" patented technology

The invention discloses a recombinant XVII type collagen engineering bacterium as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering, and the recombinant XVII type collagen engineering bacterium is realized through three steps of designing and optimizing collagen, improving translation through codon optimization and selecting a vector for cloning. By optimizing the amino acid sequence and the codon, the expression efficiency and the stability of the recombinant XVII type collagen in engineering bacteria are improved. The optimization not only improves the production efficiency of the protein, but also reduces the production cost. The recombinant XVII type collagen has potential in the medical field, especially in the fields of skin repair, wound healing, aging resistance and the like. Meanwhile, in the fields of beauty and biological materials, collagen is widely applied to products such as masks and skin care products as a basic component, and can promote skin cell regeneration and enhance skin elasticity and repair capacity.

Use of an active peptide in the manufacture of a product to improve the skin barrier and promote collagen expression and / or increase skin elasticity and suppleness and / or reduce wrinkles, characterized in that the active peptide has the structural formula HA-OH, wherein A comprises at least two amino acid residues, and the amino acid residues comprise at least one from Hyp, Gly, Pro and Ala.

The invention discloses a spot-fading, whitening and skin-tightening composition and a preparation method thereof, and particularly belongs to the technical field of cosmetics. The composition is prepared from an extract of bark of the cissampelos maculata, hydroxyl pinacolone 9-cis-retinoate, sclareolide, tetrahydromagnolol and a quercetin dimer. The composition provided by the invention can significantly reduce the skin melanin content, improve the skin brightness and significantly improve the skin elasticity and compactness, all the components have a synergistic effect, the effects of spot fading, whitening and skin tightening are effectively achieved, the preparation process provided by the invention is stable and controllable, and the composition is suitable for large-scale production and has wide application prospects. A novel efficient skin care composition and an application scheme are provided for the field of cosmetics.

The utility model discloses a skin elasticity detection device which comprises a track base, the outer surface of the track base is sleeved with a movable seat in a sliding mode, the top of the movable seat is fixedly connected with a vertical rod, one side of the outer surface of the vertical rod is rotationally connected with a large arm, one side of the outer surface of the large arm is rotationally connected with a small arm, and the small arm is fixedly connected with the track base. One side of the outer surface of each small arm is rotationally connected with a connecting base, and locking assemblies are jointly installed between the vertical rod and the large arms, between the large arms and between the small arms and the connecting bases; and one side of the outer surface of the connecting seat is fixedly connected with a traction assembly. According to the skin detection device, the movable seat, the vertical rod, the large arm, the small arm, the connecting seat, the locking assembly, the traction assembly, the detection assembly and the vacuum pump are arranged, the whole skin detection device adopts a multi-connecting-rod structural design, and the position of the detection assembly can be correspondingly adjusted according to the position of a skin detection point to be detected of a detected person, so that the actual detection scene requirement is met, and the use effect is guaranteed.

This needle assembly for a laser treatment directly radiates laser into skin by using a needle having an optical fiber inserted therein, and thus may effectively improve various skin problems such as elasticity, wrinkles, inflammation, and acne. In addition, local regional treatment is enabled so that side-effects resulting from the laser irradiation may be minimized and the pain of a subject being treated may be reduced. The needle assembly for a laser treatment comprises: a needle part comprising a hollow needle and a needle support part having one end portion of the needle passing therethrough and fixed therein; an optical fiber positioned inside the needle along the length direction such that one end of the optical fiber is not exposed to the outside of the tip portion of the needle; an optical fiber support part connected to the other end of the one end of the optical fiber; and a guide component positioned between the needle support part and the optical fiber support part so as to guide the insertion of the optical fiber into the hollow of the needle.

A method for improving skin elasticity includes use of a composition containing an ethanol-extracted product of Aronia melanocarpa fruit and Bifidobacterium longum CB108 which is deposited at the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH under an accession number DSM 33895 in accordance with the Budapest Treaty.

The present invention relates to a composition comprising plant extracts. The composition according to the present invention has a skin whitening effect by reducing the total amount of melanin and tyrosinase activity in melanocytes of the skin, promotes skin regeneration and increases skin elasticity or reduces skin wrinkles by promoting collagen synthesis and inhibiting collagenase activity in fibroblasts of the skin, has an anti-inflammatory effect or a skin soothing effect by inhibiting NO generation, increases the amount of moisture in the skin and has a moisturizing effect by promoting generation of hyaluronic acid in fibroblasts, and has an antioxidant effect by scavenging free radicals. In addition, since the composition of the present invention exhibits a broad antibacterial effect against various bacteria, the composition may be used as a cosmetic composition, a pharmaceutical composition, a skin external preparation, or a food composition.

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

The application discloses a composition with long-acting anti-wrinkle, skin elasticity improvement and skin tightening effects, a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition comprises the following efficacy components: Schizosaccharomyces pombe ferment lysate, hydroxypropyl tetrahydropyrane triol, lactose, whey protein, lactic acid, Lactarius volemus extract and palm leaf tree extract. The eye cream prepared by using the composition has very significant long-acting anti-wrinkle, skin elasticity improvement and skin tightening effects. After 28 days of use, the R2 value of skin elasticity at the corner of the eye is increased by more than 20%, the R0 value of total skin stretching displacement is decreased by more than 40%, the proportion of wrinkle area is decreased by more than 15%, and the wrinkle depth is decreased by more than 27%. The effect after 28 days of use is also significantly better than that after 14 days of use.

This invention discloses a composition for fading dark spots, whitening, and firming the skin, and its preparation method, specifically belonging to the field of cosmetic technology. The composition contains extracts of *Bretschneidera sinensis* bark, hydroxypinazone 9-cis-retinate, sage lactone, tetrahydromagnoliol, and quercetin dimer. The composition provided by this invention can significantly reduce skin melanin content, improve skin brightness, and significantly improve skin elasticity and firmness. The synergistic effect of the components effectively achieves the effects of fading dark spots, whitening, and firming the skin. The preparation process provided by this invention is stable and controllable, suitable for large-scale production, and provides a novel and highly effective skincare composition and application solution for the cosmetic field.

The invention belongs to the technical field of cosmetics, and particularly relates to collagen peptide with an anti-aging effect as well as a preparation method and application of the collagen peptide. The amino acid sequence of the collagen peptide is as shown in SEQ ID NO.1, and the nucleotide sequence of the collagen peptide is as shown in SEQ ID NO.2. According to the invention, effective sequences of human III type and XVII type collagen are recombined to construct and express the collagen peptide Sa1, and the collagen peptide Sa1 has obvious antioxidant effect, no cytotoxicity and good safety. The skin care product added with the collagen peptide Sa1 can promote skin collagen absorption and effectively exert the anti-oxidation effect, so that the effects of improving skin elasticity and delaying skin aging are achieved.

The invention discloses a skin care product containing SOD (superoxide dismutase) oil extract for delaying skin aging and removing wrinkles, which is prepared by the following steps: S1, preparing the SOD oil extract: selecting fresh animal and plant raw materials, obtaining a crude extract rich in SOD by adopting a low-temperature extraction method, and separating and purifying by utilizing technologies such as high-speed centrifugation and ultrafiltration to obtain the high-purity SOD extract, so as to obtain the SOD oil extract; the purified SOD extract is mixed with natural oil in proportion. The invention relates to the technical field of skin care products. According to the SOD oil extract-containing skin care product for delaying skin aging and removing wrinkles, SOD and natural oil are mixed to form the SOD oil extract, the stability of SOD in the skin care product is effectively improved, the activity preservation time of the SOD is prolonged, various effective components in the formula cooperate with one another, the SOD is responsible for scavenging free radicals, and the skin care effect is improved. Sodium hyaluronate and collagen maintain skin moisture and enhance skin elasticity, and vitamin E assists in resisting oxidation, so that the effects of delaying skin aging and removing wrinkles are jointly achieved.

The present invention relates to a cosmetic composition for improving skin elasticity or reducing pore size, comprising an amphiphilic biocompatible polymer. The composition promotes collagen production, inhibits collagen degradation, and suppresses elastin degradation, and thus can be effectively used as a cosmetic composition for reducing the number of pores and decreasing pore areas.

The present invention relates to a cosmetic composition for skin elasticity enhancement, skin wrinkle alleviation, and skin whitening, comprising a fermented extract of Perilla frutescens var. acuta Kudo as an active ingredient. The cosmetic composition comprising a fermented extract of Perilla frutescens var. acuta Kudo as an active ingredient, according to one embodiment of the present invention, comprises components derived from natural products and thus is harmless to the human body and exhibits remarkable efficacy in increasing collagen production and ability to inhibit melanin production, thereby being useful for skin elasticity enhancement, skin wrinkle alleviation, and skin whitening.

The invention relates to an anti-saccharification composition applicable to sensitive skin and application, and belongs to the technical field of cosmetics. The anti-saccharification composition suitable for sensitive skin is prepared from the following components in parts by mass: 0.01 to 0.5 part of ascorbic acid polypeptide, 0.5 to 2 parts of ginseng root extract, 0.1 to 2 parts of acetyl tetrapeptide-2 and 0.1 to 5 parts of herba andrographitis leaf extract. The anti-saccharification composition suitable for the sensitive skin, provided by the invention, has a remarkable anti-saccharification effect, can remarkably improve skin elasticity, has a certain repairing effect and is suitable for the sensitive skin.

According to certain described aspects, multiple acoustic sensing elements are employed in a variety of beneficial ways to provide improved physiological monitoring, among other advantages. In various embodiments, sensing elements can be advantageously employed in a single sensor package, in multiple sensor packages, and at a variety of other strategic locations in the monitoring environment. According to other aspects, to compensate for skin elasticity and attachment variability, an acoustic sensor support is provided that includes one or more pressure equalization pathways. The pathways can provide an air-flow channel from the cavity defined by the sensing elements and frame to the ambient air pressure.

1. Name of the product in this design: Skin Analyzer (JC-03). 2. Purpose of this design: To test skin elasticity. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

This invention belongs to the field of cosmetic technology, specifically relating to a collagen peptide with anti-aging effects, its preparation method, and its application. The amino acid sequence of the collagen peptide is shown in SEQ ID NO.1, and the nucleotide sequence is shown in SEQ ID NO.2. This invention constructs and expresses a collagen peptide Sa1 by recombining the effective sequences of human type III and XVII collagen. This collagen peptide Sa1 exhibits significant antioxidant effects, is non-cytotoxic, and has good safety. Skincare products containing collagen peptide Sa1 can promote the absorption of collagen in the skin, effectively exert antioxidant effects, thereby improving skin elasticity and delaying skin aging.

This invention discloses a collagen tripeptide composition, its preparation method, and its application, belonging to the field of food technology. The collagen tripeptide composition comprises the following raw materials in parts by weight: 80-200 parts of ray collagen peptide, 70-120 parts of collagen tripeptide, 100-300 parts of French flower and fruit powder, 300-600 parts of prickly pear powder, 300-500 parts of sage extract, 100-150 parts of tremella polysaccharide, 300-500 parts of wolfberry powder, and 100-300 parts of astragalus powder. The collagen tripeptide composition of this invention can reduce β-galactosidase activity, exhibiting a good anti-aging effect. Applying the collagen tripeptide composition of this invention can quickly replenish collagen and maintain skin elasticity.

The invention discloses a method for preparing silk fibroin and hyaluronic acid composite gel, which comprises the following steps of: uniformly mixing hyaluronate with a first solvent to prepare hyaluronic acid gel, mixing the hyaluronic acid gel with a silk fibroin solution, shearing at a high speed, homogenizing and emulsifying, standing, shearing at a high speed, homogenizing and emulsifying, sealing and sterilizing to obtain the silk fibroin and hyaluronic acid composite gel. According to the method disclosed by the invention, reagents such as a cross-linking agent, an initiator and enzyme do not need to be additionally added; the silk fibroin solution and the hyaluronic acid gel can form uniform and mutually-crosslinked double networks in the homogeneous gel forming process, the phase separation risk is low, and the silk fibroin can generate an emulsion reaction through high-speed homogenization, so that the color of the composite gel is whiter; the preparation method disclosed by the invention is simple, rapid in emulsification and gel forming, short in production cycle, low in endotoxin of the product, high in biocompatibility, slow in degradation, small in inflammatory response and high in injection filling safety, and the composite gel can play a role in moisturizing and moisturizing after subcutaneous injection and has the whitening effects of improving skin elasticity and glossiness, fading fine wrinkles and the like.

This invention discloses a layered anti-aging composition and its application. It comprises 4-10 parts of *Vigna angularis* fruit extract, 0.01-0.2 parts of soluble collagen, and 10-20 parts of *Fucus vesiculosus* extract, all parts by weight. The composition of this invention employs a layered anti-aging skincare strategy ("layered" generally refers to different skin areas, i.e., "cellular layer-dermis-epidermal layer"). This composition can promote the expression of LOR (lower retinal occlusion) and the relative expression level of TGM5 (epidermis), increase the content of type I procollagen C-terminal peptide and elastin (dermis), enhance mitochondrial activity, and increase ATP content (cellular layer). That is, it works progressively from the epidermis to the dermis to the cellular layer, having a relevant effect on each layer of skin, and possessing the functions of enhancing skin elasticity, firming, anti-aging, and repairing the skin barrier.

The application provides a preparation method and application of an anti-aging and anti-oxidation composite peptide, and belongs to the technical field of biology. The composite peptide is extracted from mud snails and white flowers of horse chestnut, and comprises the following steps: live body electric stimulation induction of the mud snails, biomimetic mineralization wall breaking of the mud snails, composite directional enzymolysis of the mud snails and the white flowers of horse chestnut, crosslinking and purification. The obtained composite peptide can not only effectively remove free radicals and reduce the damage of oxidative stress to cells, but also has the effects of promoting collagen synthesis, stimulating cell regeneration, improving skin elasticity, slowing down wrinkle formation and improving skin gloss. The composite peptide can be widely applied to cosmetics and medicines as an effective component for delaying aging and protecting cell health.

The present invention provides a skin elasticity and skin moisturizing functional cosmetic composition containing a Boryeong mud extract.

The present invention relates to a composition comprising an anti-aging peptide and, more specifically, to an anti-aging cosmetic, food, and pharmaceutical composition comprising the anti-aging peptide. The anti-aging peptide according to the present invention not only exhibits excellent skin permeability, but also demonstrates remarkable antioxidant activity, wrinkle reduction, skin elasticity enhancement, collagenase inhibition, or hyaluronidase inhibition effects, as confirmed experimentally. These findings indicate that the anti-aging peptide of the present invention possesses excellent anti-aging activity and thus can be variously used as a functional material in pharmaceutical, medicinal, cosmetic, and food fields.

The present invention relates to a thread inserter and, more specifically, to a thread inserter in which a thread, which is inserted into the human body and is retained to increase the elasticity of skin and improve wrinkles, and an injection needle for guiding the thread into the human body are combined with each other. The thread inserter according to one embodiment of the present invention comprises: an insertion needle extending in the longitudinal direction, having a hole opened from the inside thereof to the front end thereof, and having a handle at the rear end thereof; a guide thread having respective ends inserted into the hole at the front end of the insertion needle, and having a middle portion bent outside the hole to form an arc-shaped thread hanging part; an embedding thread connected to the thread hanging part of the guide thread and extending along the longitudinal direction outside the insertion needle; and a winding thread tightly wound around the outer circumferential surface of the insertion needle in a coil shape along the longitudinal direction thereof. The guide thread, the embedding thread, and the winding thread formed on the insertion needle are inserted into the human body together with the insertion needle, after which the insertion needle is withdrawn from the body, and the guide thread, the embedding thread, and the winding thread are retained in the body.

This invention belongs to the field of cosmetic technology, specifically relating to an anti-aging composition containing lactoferrin and its application. The anti-aging composition provided by this invention, through scientific compounding, achieves synergistic effects in anti-aging among four components: medicinal Fomitopsis thunbergii extract, butterfly pea flower extract, Artemisia annua extract, and lactoferrin. This results in excellent elastase inhibition, preventing the degradation of elastin in the dermis and effectively strengthening the elastin scaffold, thereby enhancing the anti-aging effect of the composition. When applied to a prepared emulsion, this anti-aging composition can improve skin firmness (R0 change rate), skin elasticity (R2 change rate), and facial wrinkles (wrinkle change rate), exhibiting anti-aging effects of improving wrinkle reduction and firmness, and promoting skin elasticity. Furthermore, it does not cause skin irritation, possessing safe and gentle characteristics, a wide range of applications, and high consumer acceptance.

The present application provides a peptide having the formula (I) R1-Ser-Pro-X1-Gln-R2 or a cosmetically or pharmaceutically acceptable salt thereof, or a cosmetic or pharmaceutical composition thereof, and their use in the preparation of a cosmetic or pharmaceutical composition for treating, preventing or repairing skin aging or photoaging, promoting collagen production, increasing skin elasticity and / or skin firmness, promoting PER1 protein expression, regulating skin circadian rhythm and / or repairing damaged skin cells. The peptide of formula (I) regulates the expression of skin circadian cycle regulation genes and related proteins, regulates skin circadian rhythm and resynchronizes skin cell biological clock, enhances cell vitality, repairs damaged cells, thereby alleviating signs of skin aging, and can be used in the field of cosmetics or medicine to resist skin aging, and can also be used to prepare a PER1 protein activator.

This invention discloses a multi-target anti-aging composition and its application in cosmetics. By weight, it comprises the following ingredients: 0.001–3 parts hydroxypinazone retinate, 0.01–5 parts hydroxypropyl tetrahydropyranotriol, 0.01–0.5 parts recombinant human collagen, 0.5–3 parts tocopheryl acetate, 0.1–5 parts glyceryl glucoside, 0.01–5 parts Babao Essence Extract, 0.01–0.5 parts carnosine, 0.5–2 parts 3000 peptides, 0.1–5 parts Bifida ferment lysate, 0.01–0.5 parts coenzyme Q10, and 0.1–5 parts black tea fermentation product. This multi-target anti-aging composition targets four aspects: anti-aging, anti-oxidation, anti-glycation, and anti-photochemical activity. The four categories of components work synergistically to significantly enhance the anti-aging efficacy of the product. Human efficacy evaluation tests show that after using the product of this invention for 28 days, the elasticity of the skin around the eyes is significantly increased, the firmness and roughness of the skin around the eyes are significantly improved, and the area, volume and depth of wrinkles at the corners of the eyes are significantly improved.

This invention provides a composition that inhibits the tyrosinase enzyme involved in melanin production and also inhibits the action of collagen-degrading enzymes, thereby promoting collagen synthesis and achieving sufficient effects of skin whitening and elasticity improvement without inducing skin irritation due to skin allergies. [Solution] A composition having skin whitening and skin elasticity improving effects, according to one embodiment of the present invention, contains ginger extract as an active ingredient, and the ginger extract can be extracted using methylene chloride.

The application discloses a kind of shallow liposuction skin tightening methods, it is related to medical cosmetology technical field, the method is by integrating micro tension sensor array in the side wall of liposuction needle tube, the longitudinal and transverse tension data of subcutaneous tissue at different depths are collected in real time during needle tube advancement;The collected data are compared with the pre-stored skin elasticity modulus database, to determine whether the current liposuction level is in the preset shallow safe tightening zone;When the judgment result is in the safe tightening zone and the real-time tension is lower than the threshold value, the gradient radiofrequency electrode of needle tube outer wall is automatically triggered, and the radiofrequency heat energy is released according to the deep-middle-shallow three-level energy progression mode, and collagen contraction and new growth are stimulated simultaneously;Tension change is continuously monitored and energy parameters are dynamically adjusted until the target tightness is reached.The method realizes the closed-loop control of "perception-judgment-response" during operation, significantly reduces the postoperative skin relaxation rate, significantly improves the immediate postoperative tightness, and can be widely used in the precision improvement of body sculpture surgery.