389 results about "Skin elasticity" patented technology

The invention belongs to the technical field of cosmetics, and discloses anti-aging recombinant collagen as well as a preparation method and application thereof. The amino acid sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.1, and the nucleotide sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.2. The recombinant collagen CaI1 is constructed and expressed by recombining the effective sequences of the I-type collagen, the III-type collagen and the XVII-type collagen, and the recombinant collagen CaI1 is free of cytotoxicity, free of hidden danger of endotoxin and good in safety. The skin care product added with the recombinant collagen CaI1 can promote skin collagen absorption, inhibit skin aging and improve skin elasticity, and has a good application prospect.

The invention discloses a scalp essence capable of controlling oil and removing dandruff and a preparation method thereof, and provides the scalp essence capable of controlling oil and removing dandruff. The formula consists of the following raw materials: water, saccharomycetes / rice fermentation product filtrate, butanediol, phenoxyethanol, caprylic acid / capric triglyceride, galactose yeast-like bacterium fermentation product filtrate, allantoin, a saccharomycetes / zinc fermentation product, nicotinamide, arginine, polysorbate-20, hydrogenated lecithin, acrylic acid (ester) / C10-30 and an alkanol acrylate cross-linked polymer. Hydrolyzed sodium hyaluronate and trace components. According to the oil-controlling and dandruff-removing scalp essence disclosed by the invention, through the synergistic interaction among the raw materials, the effects of replenishing water, preserving moisture, controlling oil and removing dandruff are increased, the effects of relieving, recovering oil-water balance, recovering skin elasticity and delaying senescence are also achieved, the effects of preventing hair loss and nourishing hair are also achieved, and meanwhile, the oil-controlling and dandruff-removing scalp essence has the advantage of being stable in storage.

The invention discloses a recombinant XVII type collagen engineering bacterium as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering, and the recombinant XVII type collagen engineering bacterium is realized through three steps of designing and optimizing collagen, improving translation through codon optimization and selecting a vector for cloning. By optimizing the amino acid sequence and the codon, the expression efficiency and the stability of the recombinant XVII type collagen in engineering bacteria are improved. The optimization not only improves the production efficiency of the protein, but also reduces the production cost. The recombinant XVII type collagen has potential in the medical field, especially in the fields of skin repair, wound healing, aging resistance and the like. Meanwhile, in the fields of beauty and biological materials, collagen is widely applied to products such as masks and skin care products as a basic component, and can promote skin cell regeneration and enhance skin elasticity and repair capacity.

The invention relates to the technical field of biological medicine, in particular to recombinant III-type humanized collagen as well as a preparation method and application thereof. In one embodiment, the recombinant III type humanized collagen prepared by the invention has an amino acid sequence as shown in SEQ ID NO: 1 or SEQ ID NO: 4. The recombinant III-type humanized collagen prepared by the invention has good biological activity, can promote collagen synthesis related gene expression, promote skin fibroblast proliferation, increase the content of skin collagenous fibers and elastic fibers, and improve skin elasticity and compactness; in addition, the expression of osteogenesis related genes is promoted, and the proliferation of osteoblasts is promoted. The results show that the recombinant III-type humanized collagen prepared by the invention has an extremely wide application prospect in developing related medical and cosmetic products for delaying skin aging and promoting wound repair and bone tissue healing.

The invention belongs to the technical field of cosmetics, and discloses a wrinkle-removing and anti-aging composition containing recombinant collagen as well as a preparation method and application of the wrinkle-removing and anti-aging composition. The composition is prepared from the following components: 20.4 to 35.6 percent of glycerol, 1.1 to 3.5 percent of 1, 2-hexanediol, 8.2 to 15.4 percent of apple fruit cell culture extract, 1.6 to 3.2 percent of inositol, 0.2 to 1.0 percent of elastin, 0.1 to 1.7 percent of hydroxyproline, 0.1 to 1.0 percent of sodium polyglutamate, 0.1 to 1.0 percent of sodium hyaluronate, 0.01 to 0.1 percent of acetyl hexapeptide-8, 0.01 to 0.1 percent of fibronectin, 1.72 to 3.21 percent of soluble collagen and the balance of deionized water. The amino acid sequence of the soluble collagen is as shown in SEQ ID NO. 1. The skin care product prepared by adding the anti-wrinkle and anti-aging composition is good in safety and has the effects of resisting wrinkles, improving skin elasticity and resisting aging.

The invention provides an anti-wrinkle combined cyclic peptide and application thereof in cosmetics, the anti-wrinkle combined cyclic peptide comprises cyclic pentapeptide-4, cyclic tripeptide-5 and cyclic hexapeptide-9, the combined cyclic peptide has a remarkable synergistic effect in the aspects of promoting expression of collagen genes Collagen I, Collagen III and Collagen IV and inhibiting acetylcholine secretion, the skin elasticity and glossiness are remarkably improved, and the anti-wrinkle combined cyclic peptide has a good anti-wrinkle effect. The generation of wrinkles is inhibited, and good anti-aging and wrinkle-removing effects are achieved.

The invention relates to a composition with anti-wrinkle and firming effects and application thereof. The composition is prepared from a brassica juncea leaf extract, a swertia indica extract, a kangaroo claw extract, a tomato fruit extract and polydeoxyribonucleotide. According to the invention, it is creatively found that the Brachirita leaf extract, the swertia indica extract, the kangaroo claw extract, the tomato fruit extract and the polydeoxyribonucleotide have a synergistic effect in the aspects of improving wrinkle resistance and tightening of skin. The composition can significantly reduce the ratio of crow's feet and nasolabial folds, improves the skin elasticity, and has excellent anti-wrinkle and firming effects.

The present invention relates to a preparation method of a collagen filler for injection. Non-crosslinked collagen, crosslinked collagen, and biodegradable polymer microspheres are compounded and mixed in a certain proportion to achieve an immediate filling effect. The biodegradable polymer microspheres play a long-term role, and the amino acid components degraded from collagen in the early and middle stages can become nutrients that stimulate the production of collagen regeneration by polyester microspheres. In the present invention, the crosslinked collagen has a high yield and less water loss through a gradient irradiation crosslinking technique. The non-crosslinked collagen gel can provide a microenvironment for nutritional repair and a filling effect in the early stage, the crosslinked extracellular matrix can provide a repair microenvironment in the middle stage of filling, and the degradation of polyester microspheres in the later stage promotes collagen regeneration, enabling the skin to have a good microenvironment throughout the repair cycle and increasing skin elasticity.

The invention belongs to the technical field of cosmetics, and discloses skin-tightening and anti-wrinkle essence. The skin-tightening anti-wrinkle essence is prepared from the following raw materials in percentage by mass: 1.5 to 2.5 percent of acetyl hexapeptide-8, 2.0 to 3.0 percent of palmitoyl pentapeptide-4, 3.0 percent of hydroxypropyl tetrahydropyrantriol, 2.0 percent of lipidosome-coated vitamin C ethyl ether, 0.5 percent of resveratrol PLGA microspheres, 0.8 percent of ceramide NP, 1.2 percent of pachymaran, 5.0 percent of glyceryl polyether-26, 0.3 percent of sodium hyaluronate, 0.5 percent of p-hydroxyacetophenone and 1, 3-propanediol, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate and the balance of water. The 1, 2-hexanediol accounts for 0.6%, and the balance is deionized water. Multi-target anti-wrinkle, deep moisturizing and long-acting repairing are achieved by scientifically compounding active ingredients such as acetyl hexapeptide-8 and palmitoyl pentapeptide-4 and combining a lipidosome wrapping technology and a nano-microsphere slow release technology, the preparation process comprises the steps of lipidosome homogenization, nano-microsphere multiple emulsion method and low-temperature emulsification, the ingredient stability and transdermal efficiency are ensured, and the skin care effect is good. Experiments prove that the essence can significantly improve skin elasticity and reduce wrinkles, and has a significant anti-aging effect.

The present invention relates to the fields of medicine and cosmetology, and discloses a cell active peptide composition that promotes the regeneration of multi-type collagen structural proteins, its preparation method, and its application in medicine and cosmetology. The composition uses raw materials such as tripeptide-10 citrulline, hexapeptide-9, hydrolyzed sodium hyaluronate, γ-aminobutyric acid, decarboxylated carnosine hydrochloride, acetyl tetrapeptide-3, acetyl tetrapeptide-11, palmitoyl dipeptide-7, and palmitoyl pentapeptide-4. The composition can promote the coordinated expression of skin type I, type III, type IV, type VII, type XVII collagen, fibronectin, elastin, and glycosaminoglycans; prevent collagen cross-linking, maintain triple helix structure, and inhibit collagen degradation. Applied to dermatology and cosmetology, it can accelerate the regeneration of structural proteins such as skin collagen, repair skin damage, reduce wrinkles such as crow's feet, tear groove lines, nasolabial folds, and under-eye lines, solve the skin aging problem caused by the loss of structural proteins such as collagen, and improve skin elasticity and firmness.

The invention provides a ginseng exosome anti-aging and anti-oxidation composition and a preparation method thereof, and relates to the field of nursing materials, the ginseng exosome anti-aging and anti-oxidation composition comprises Exo nano-vesicles, procyanidine and cationic liposome, the Exo nano-vesicles are derived from ginseng extracellular fluid, the procyanidine is derived from the cationic liposome, and the cationic liposome is derived from the procyanidine. The ginseng exosome anti-aging and anti-oxidation composition provided by the invention can effectively improve skin wrinkles, enhance skin elasticity, promote collagen synthesis, inhibit collagen degradation and inhibit elastin degradation through the combined action of the Exo nano-vesicles, Pro and cationic lipidosome; degradation of elastin can cause skin to lose resilience, formation of wrinkles is accelerated, and facial skin can be effectively improved and wrinkles can be reduced by promoting synthesis of collagen and inhibiting degradation of elastin.

The invention discloses application of a glucosyl modified quercetin derivative and a composition containing the glucosyl modified quercetin derivative. Specifically, the invention discloses an application of glucosyl modified quercetin as an anti-skin photoaging agent. According to the application disclosed by the invention, glucosyl modified quercetin, especially glucosyl modified isoquercitrin, has a remarkable effect in the aspect of resisting skin photoaging; cosmetics prepared from glucosyl modified quercetin have good anti-aging ability, and can significantly improve percutaneous water loss, skin elasticity and skin roughness.

The invention discloses a skin anti-wrinkle whitening composition containing ginkgetin and a preparation method of the skin anti-wrinkle whitening composition. The composition takes ginkgo biflavone as a main active component, has the characteristics of safety and effectiveness, can remarkably improve skin elasticity and reduce wrinkles, and has the effect of whitening skin.

The invention relates to an anti-aging composition for strengthening a skin supporting network and application thereof, and the anti-aging composition comprises the following components: a golden camellia flower extract, a saffron crocus extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, the weight ratio of the golden camellia flower extract to the saffron crocus extract to the camellia seed oil to the tranexamic acid to the epigallocatechin gallate glucoside is (0.1 to 5) to (0.01 to 5) to (0.1 to 10) to (0.01 to 2) to (0.001 to 0.1). The composition provided by the invention can synergistically strengthen a skin support network and comprehensively improve skin elasticity and compactness by promoting growth of two core structural proteins and three macromolecular adhesives of skin, and is mild, non-irritant and suitable for people with sensitive skin.

The scar removing cream is prepared from the following raw materials in percentage by weight: 30 to 80 percent of silica gel component, 5 to 30 percent of solvent, 0.1 to 10 percent of emulsifying agent, 1 to 5 percent of thickening agent, 0.01 to 10 percent of extract / synergistic component, 0.1 to 20 percent of medicament component, 1 to 50 percent of moisturizing component, 0.01 to 0.1 percent of growth factor, 0.1 to 2 percent of other component, 0.01 to 0.5 percent of preservative and 0.1 to 2 percent of pH (Potential of Hydrogen) regulator. The traditional Chinese medicine composition has the effects of improving skin repair, whitening and diminishing inflammation, accelerates skin elasticity recovery and reduces scars.

The invention relates to an anti-aging composition and application thereof. The anti-aging composition is prepared from the following raw materials: dendrobium officinale, camellia japonica and polygonatum kingianum. Dendrobium officinale, camellia japonica and polygonatum kingianum cooperate with one another to achieve a synergistic effect, secretion of type I collagen (COL-1) can be promoted, secretion of matrix metalloproteinase-1 (MMP-1) can be inhibited, and decomposition of collagen in extracellular matrixes can be slowed down. The anti-aging composition can increase skin elasticity, improve the skin barrier function, reduce the percutaneous water loss rate and delay skin aging.

The invention provides a method and system for evaluating facial skin aging, and the method comprises the steps: obtaining visible light, ultraviolet reflection and near-infrared spectrum images through multispectral imaging, and extracting skin texture, color spots and capillary network parameters through preprocessing; constructing a three-dimensional facial skin model, and measuring skin elasticity parameters in combination with a mechanical sensor; and inputting the parameters into a deep learning aging evaluation model, outputting a comprehensive evaluation report containing the physiological age of the skin, the elasticity grade and the regional aging difference index, and providing personalized aging protection suggestions. According to the method, multi-modal data and a deep learning technology are fused, multi-dimensional quantitative evaluation is realized, the method has the characteristics of high precision, objectivity and individuation, a powerful tool is provided for skin health management, and the method has a wide application prospect.

The invention provides recombinant humanized elastin with an effect of improving endogenous skin aging and application of the recombinant humanized elastin, and belongs to the technical field of crossing of dermatology and biological materials. The recombinant humanized elastin is based on a human elastin core function sequence, recombinant optimization and efficient expression are carried out by adopting a synthetic biological strategy, and excellent stability and biological activity are shown. The recombinant humanized elastin can be used for constructing a skin repair dressing, and synergistically improves endogenous aging characteristics such as skin elasticity reduction, collagen loss and high oxidative stress by remodeling an extracellular matrix network structure. Animal experiments prove that a product based on the recombinant humanized elastin has good tissue repair capacity, biocompatibility and antioxidant activity, and can be widely applied to functional skin care products and medical cosmetic preparations.

The invention relates to a composition for promoting collagen generation based on sophora flower powder as well as a preparation method and application of the composition, and belongs to the technical field of sophora flower extracts. A preparation method of the sophora flower powder extract comprises the following steps: taking sophora flower powder, adding water, boiling, cooling, adding a carbon source and aspergillus oryzae CICC 2066, fermenting, sterilizing, filtering, concentrating and freeze-drying to obtain the sophora flower powder extract. The sophora flower powder extract can be applied to food, can also be applied to cosmetics, and can effectively promote the generation of collagen and improve the skin elasticity and tightening effect.

The invention discloses preparation and application of a whitening and repairing composition containing temperature-sensitive oxidized resveratrol hydrogel, and relates to the technical field of cosmetics. The composition comprises the following components in parts by weight: 1-5 parts of temperature-sensitive oxidized resveratrol hydrogel, 4-6 parts of a peucedanum praeruptorum dunn extract, 1-3 parts of a willowleaf swallowwort rhizome extract and 0.1-0.5 part of a tephrosia rubescens seed extract. The combination of the peucedanum praeruptorum dunn extract, the cynanchum wilfordii extract, the tephros glauca seed extract and the oxyresveratrol finds that the composition has a synergistic interaction effect, and the composition formed by the components through specific compatibility has the effects of whitening, repairing and improving skin elasticity. The oxidized resveratrol is wrapped by the temperature-sensitive hydrogel, so that the oxidized resveratrol is kept in a gel state at an epidermal cuticle layer, and after the oxidized resveratrol permeates into a skin basal layer, the oxidized resveratrol can be released at the skin basal layer, acts on melanocytes more effectively, inhibits tyrosinase and further affects generation of melanin.

The invention discloses an anti-wrinkle firming composition and application thereof, and particularly belongs to the technical field of skin care products. The composition is prepared from the following components in parts by mass: 0.1 to 10 parts of rhodiola rosea extract, 5 to 20 parts of hydroxypropyl tetrahydropyrantriol, 0.02 to 2 parts of polyrock extract and 0.5 to 2 parts of adenosine, wherein the polyrock extract is obtained by carrying out compound fermentation on lactobacillus acidophilus and bacillus licheniformis; according to the anti-wrinkle and firming composition provided by the invention, when the rhodiola rosea extract, the hydroxypropyl tetrahydropyrantriol, the polyrock extract and the adenosine are compounded for use, excellent effects of resisting oxidation and promoting collagen synthesis are shown; the anti-wrinkle and firming emulsion provided by the invention can effectively reduce wrinkles and improve skin elasticity, shows excellent performance, overcomes the problems of efficacy limitation and single action mechanism of a single component, and realizes efficient anti-wrinkle and firming effects under a multi-channel synergistic effect.

The invention discloses eye cream capable of repairing, resisting wrinkles and removing dark circles and a preparation method thereof.The eye cream is prepared from a skin conditioner, an emollient, a hydroxyl-containing substance, an emulsifier, a viscous substance extract, a chelating agent and deionized water, and the obtained eye cream is good in dispersion stability, has good heat resistance and cold resistance, can be stored for a long time and is free of toxic and side effects. The effects of beautifying and retaining youthful looks can be achieved through the effects of delaying body aging, regulating endocrine and metabolic systems, eliminating free radicals and the like, and the effects of restoring skin elasticity, enabling the skin to be moist and fine, inhibiting formation and precipitation of melanin in the skin, effectively removing dark circles, minimizing pores, resisting aging, whitening, resisting oxidation, preserving moisture and repairing are achieved. Besides, the preparation process is simple and easy to operate, the used components are mild and non-irritating, the problems of overhigh local nutrition of eyes and the like are avoided, and the eye cream is smooth to smear, good in fragrance and easy to absorb in the using process and can meet multiple requirements of different skin types for resisting wrinkles, removing dark circles and the like.

The invention discloses application of a firming and stability-maintaining periocular conditioning composition in skin care products, and the firming and stability-maintaining periocular conditioning composition is used for improving fragrance and promoting absorption. The composition prepared by compounding the specific components including the barrier repairing agent, the emollient, the hydroxyl compound, the surfactant, the thickener and the chelating agent in proportion has good heat resistance and cold resistance, is good in stability, can be stored for a long time, can promote regeneration of eye skin cells, keeps and regulates skin moisture, recovers skin elasticity, and has a good application prospect. The eye cream has the effects of whitening skin, delaying body aging, resisting oxidation, whitening skin, resisting inflammation and bacteria, inhibiting formation and precipitation of melanin in skin, effectively removing dark circles, minimizing pores and tightening eye skin. Besides, when the composition is used for an eye skin care product, the composition is good in fragrance, fast in absorption and smooth in smearing, the mud rubbing phenomenon is avoided, the situation that fine lines of eyes are further deepened due to the fact that the force is difficult to control in the smearing process is avoided, and the multiple requirements for wrinkle resistance, dark circle removal and the like of different skin types can be met.

Use of an active peptide in the manufacture of a product to improve the skin barrier and promote collagen expression and / or increase skin elasticity and suppleness and / or reduce wrinkles, characterized in that the active peptide has the structural formula HA-OH, wherein A comprises at least two amino acid residues, and the amino acid residues comprise at least one from Hyp, Gly, Pro and Ala.

The invention discloses a spot-fading, whitening and skin-tightening composition and a preparation method thereof, and particularly belongs to the technical field of cosmetics. The composition is prepared from an extract of bark of the cissampelos maculata, hydroxyl pinacolone 9-cis-retinoate, sclareolide, tetrahydromagnolol and a quercetin dimer. The composition provided by the invention can significantly reduce the skin melanin content, improve the skin brightness and significantly improve the skin elasticity and compactness, all the components have a synergistic effect, the effects of spot fading, whitening and skin tightening are effectively achieved, the preparation process provided by the invention is stable and controllable, and the composition is suitable for large-scale production and has wide application prospects. A novel efficient skin care composition and an application scheme are provided for the field of cosmetics.

The utility model discloses a skin elasticity detection device which comprises a track base, the outer surface of the track base is sleeved with a movable seat in a sliding mode, the top of the movable seat is fixedly connected with a vertical rod, one side of the outer surface of the vertical rod is rotationally connected with a large arm, one side of the outer surface of the large arm is rotationally connected with a small arm, and the small arm is fixedly connected with the track base. One side of the outer surface of each small arm is rotationally connected with a connecting base, and locking assemblies are jointly installed between the vertical rod and the large arms, between the large arms and between the small arms and the connecting bases; and one side of the outer surface of the connecting seat is fixedly connected with a traction assembly. According to the skin detection device, the movable seat, the vertical rod, the large arm, the small arm, the connecting seat, the locking assembly, the traction assembly, the detection assembly and the vacuum pump are arranged, the whole skin detection device adopts a multi-connecting-rod structural design, and the position of the detection assembly can be correspondingly adjusted according to the position of a skin detection point to be detected of a detected person, so that the actual detection scene requirement is met, and the use effect is guaranteed.

The invention belongs to the technical field of cosmetics, and particularly discloses a cosmetic composition and eye cream for fading dark circles of eyes and a preparation method, the cosmetic composition is prepared from the following raw materials in parts by weight: 0.1-2 parts of Mailong eight-treasure raw powder, 0.1-2 parts of sialic acid, 0.1-5 parts of caffeine, 0.01-1 part of glucosyl hesperidin, 0.01-2 parts of mulberry root bark extract and 0.1-5 parts of botryine. The cosmetic composition provided by the invention can effectively improve the skin microcirculation around eyes, enhance the elasticity of the skin around eyes and reduce hyperpigmentation, so that dark circles around the eyes are obviously faded, and meanwhile, the cosmetic composition also has the advantages of small irritation and high safety; the prepared eye cream is high in stability and small in irritation; meanwhile, the whole process of the eye cream is simple, easy to implement and suitable for industrial production and application.

This needle assembly for a laser treatment directly radiates laser into skin by using a needle having an optical fiber inserted therein, and thus may effectively improve various skin problems such as elasticity, wrinkles, inflammation, and acne. In addition, local regional treatment is enabled so that side-effects resulting from the laser irradiation may be minimized and the pain of a subject being treated may be reduced. The needle assembly for a laser treatment comprises: a needle part comprising a hollow needle and a needle support part having one end portion of the needle passing therethrough and fixed therein; an optical fiber positioned inside the needle along the length direction such that one end of the optical fiber is not exposed to the outside of the tip portion of the needle; an optical fiber support part connected to the other end of the one end of the optical fiber; and a guide component positioned between the needle support part and the optical fiber support part so as to guide the insertion of the optical fiber into the hollow of the needle.

An anti-aging injection composition, an anti-aging injection, and use thereof. The anti-aging injection composition contains hyaluronic acid or a salt thereof, glycine, proline, lysine hydrochloride, and leucine, which can synergistically promote the generation of collagen and elastin in the skin, thereby helping to correct skin wrinkles, improve skin elasticity, and enhance skin radiance. The anti-aging injection composition can be used to prepare an anti-aging injection, which has the effect of resisting skin aging.

The invention relates to application of a fish maw and colla corii asini composition in preparation of anti-aging products, and belongs to the technical field of health-care products. The mass ratio of the fish maw to the colla corii asini in the fish maw and colla corii asini composition is (1-2): 1, and the colla corii asini is Dongshan colla corii asini powder. The fish maw and colla corii asini composition has the advantages that the anti-oxidation level, the collagen metabolism level and the cell function level are mutually cooperated, the anti-oxidation capability is obviously improved, the dermis layer is delayed to be thinned, the skin elasticity is effectively improved, and the anti-aging effect is achieved.