285 results about "Skin elasticity" patented technology

The invention discloses a recombinant XVII type collagen engineering bacterium as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering, and the recombinant XVII type collagen engineering bacterium is realized through three steps of designing and optimizing collagen, improving translation through codon optimization and selecting a vector for cloning. By optimizing the amino acid sequence and the codon, the expression efficiency and the stability of the recombinant XVII type collagen in engineering bacteria are improved. The optimization not only improves the production efficiency of the protein, but also reduces the production cost. The recombinant XVII type collagen has potential in the medical field, especially in the fields of skin repair, wound healing, aging resistance and the like. Meanwhile, in the fields of beauty and biological materials, collagen is widely applied to products such as masks and skin care products as a basic component, and can promote skin cell regeneration and enhance skin elasticity and repair capacity.

The invention belongs to the technical field of cosmetics, and discloses a wrinkle-removing and anti-aging composition containing recombinant collagen as well as a preparation method and application of the wrinkle-removing and anti-aging composition. The composition is prepared from the following components: 20.4 to 35.6 percent of glycerol, 1.1 to 3.5 percent of 1, 2-hexanediol, 8.2 to 15.4 percent of apple fruit cell culture extract, 1.6 to 3.2 percent of inositol, 0.2 to 1.0 percent of elastin, 0.1 to 1.7 percent of hydroxyproline, 0.1 to 1.0 percent of sodium polyglutamate, 0.1 to 1.0 percent of sodium hyaluronate, 0.01 to 0.1 percent of acetyl hexapeptide-8, 0.01 to 0.1 percent of fibronectin, 1.72 to 3.21 percent of soluble collagen and the balance of deionized water. The amino acid sequence of the soluble collagen is as shown in SEQ ID NO. 1. The skin care product prepared by adding the anti-wrinkle and anti-aging composition is good in safety and has the effects of resisting wrinkles, improving skin elasticity and resisting aging.

The invention provides an anti-wrinkle combined cyclic peptide and application thereof in cosmetics, the anti-wrinkle combined cyclic peptide comprises cyclic pentapeptide-4, cyclic tripeptide-5 and cyclic hexapeptide-9, the combined cyclic peptide has a remarkable synergistic effect in the aspects of promoting expression of collagen genes Collagen I, Collagen III and Collagen IV and inhibiting acetylcholine secretion, the skin elasticity and glossiness are remarkably improved, and the anti-wrinkle combined cyclic peptide has a good anti-wrinkle effect. The generation of wrinkles is inhibited, and good anti-aging and wrinkle-removing effects are achieved.

The invention relates to a composition with anti-wrinkle and firming effects and application thereof. The composition is prepared from a brassica juncea leaf extract, a swertia indica extract, a kangaroo claw extract, a tomato fruit extract and polydeoxyribonucleotide. According to the invention, it is creatively found that the Brachirita leaf extract, the swertia indica extract, the kangaroo claw extract, the tomato fruit extract and the polydeoxyribonucleotide have a synergistic effect in the aspects of improving wrinkle resistance and tightening of skin. The composition can significantly reduce the ratio of crow's feet and nasolabial folds, improves the skin elasticity, and has excellent anti-wrinkle and firming effects.

The present invention relates to the fields of medicine and cosmetology, and discloses a cell active peptide composition that promotes the regeneration of multi-type collagen structural proteins, its preparation method, and its application in medicine and cosmetology. The composition uses raw materials such as tripeptide-10 citrulline, hexapeptide-9, hydrolyzed sodium hyaluronate, γ-aminobutyric acid, decarboxylated carnosine hydrochloride, acetyl tetrapeptide-3, acetyl tetrapeptide-11, palmitoyl dipeptide-7, and palmitoyl pentapeptide-4. The composition can promote the coordinated expression of skin type I, type III, type IV, type VII, type XVII collagen, fibronectin, elastin, and glycosaminoglycans; prevent collagen cross-linking, maintain triple helix structure, and inhibit collagen degradation. Applied to dermatology and cosmetology, it can accelerate the regeneration of structural proteins such as skin collagen, repair skin damage, reduce wrinkles such as crow's feet, tear groove lines, nasolabial folds, and under-eye lines, solve the skin aging problem caused by the loss of structural proteins such as collagen, and improve skin elasticity and firmness.

The invention provides a ginseng exosome anti-aging and anti-oxidation composition and a preparation method thereof, and relates to the field of nursing materials, the ginseng exosome anti-aging and anti-oxidation composition comprises Exo nano-vesicles, procyanidine and cationic liposome, the Exo nano-vesicles are derived from ginseng extracellular fluid, the procyanidine is derived from the cationic liposome, and the cationic liposome is derived from the procyanidine. The ginseng exosome anti-aging and anti-oxidation composition provided by the invention can effectively improve skin wrinkles, enhance skin elasticity, promote collagen synthesis, inhibit collagen degradation and inhibit elastin degradation through the combined action of the Exo nano-vesicles, Pro and cationic lipidosome; degradation of elastin can cause skin to lose resilience, formation of wrinkles is accelerated, and facial skin can be effectively improved and wrinkles can be reduced by promoting synthesis of collagen and inhibiting degradation of elastin.

The invention discloses a skin anti-wrinkle whitening composition containing ginkgetin and a preparation method of the skin anti-wrinkle whitening composition. The composition takes ginkgo biflavone as a main active component, has the characteristics of safety and effectiveness, can remarkably improve skin elasticity and reduce wrinkles, and has the effect of whitening skin.

The invention provides a method and system for evaluating facial skin aging, and the method comprises the steps: obtaining visible light, ultraviolet reflection and near-infrared spectrum images through multispectral imaging, and extracting skin texture, color spots and capillary network parameters through preprocessing; constructing a three-dimensional facial skin model, and measuring skin elasticity parameters in combination with a mechanical sensor; and inputting the parameters into a deep learning aging evaluation model, outputting a comprehensive evaluation report containing the physiological age of the skin, the elasticity grade and the regional aging difference index, and providing personalized aging protection suggestions. According to the method, multi-modal data and a deep learning technology are fused, multi-dimensional quantitative evaluation is realized, the method has the characteristics of high precision, objectivity and individuation, a powerful tool is provided for skin health management, and the method has a wide application prospect.

The invention provides recombinant humanized elastin with an effect of improving endogenous skin aging and application of the recombinant humanized elastin, and belongs to the technical field of crossing of dermatology and biological materials. The recombinant humanized elastin is based on a human elastin core function sequence, recombinant optimization and efficient expression are carried out by adopting a synthetic biological strategy, and excellent stability and biological activity are shown. The recombinant humanized elastin can be used for constructing a skin repair dressing, and synergistically improves endogenous aging characteristics such as skin elasticity reduction, collagen loss and high oxidative stress by remodeling an extracellular matrix network structure. Animal experiments prove that a product based on the recombinant humanized elastin has good tissue repair capacity, biocompatibility and antioxidant activity, and can be widely applied to functional skin care products and medical cosmetic preparations.

The invention relates to a composition for promoting collagen generation based on sophora flower powder as well as a preparation method and application of the composition, and belongs to the technical field of sophora flower extracts. A preparation method of the sophora flower powder extract comprises the following steps: taking sophora flower powder, adding water, boiling, cooling, adding a carbon source and aspergillus oryzae CICC 2066, fermenting, sterilizing, filtering, concentrating and freeze-drying to obtain the sophora flower powder extract. The sophora flower powder extract can be applied to food, can also be applied to cosmetics, and can effectively promote the generation of collagen and improve the skin elasticity and tightening effect.

Use of an active peptide in the manufacture of a product to improve the skin barrier and promote collagen expression and / or increase skin elasticity and suppleness and / or reduce wrinkles, characterized in that the active peptide has the structural formula HA-OH, wherein A comprises at least two amino acid residues, and the amino acid residues comprise at least one from Hyp, Gly, Pro and Ala.

The invention discloses a spot-fading, whitening and skin-tightening composition and a preparation method thereof, and particularly belongs to the technical field of cosmetics. The composition is prepared from an extract of bark of the cissampelos maculata, hydroxyl pinacolone 9-cis-retinoate, sclareolide, tetrahydromagnolol and a quercetin dimer. The composition provided by the invention can significantly reduce the skin melanin content, improve the skin brightness and significantly improve the skin elasticity and compactness, all the components have a synergistic effect, the effects of spot fading, whitening and skin tightening are effectively achieved, the preparation process provided by the invention is stable and controllable, and the composition is suitable for large-scale production and has wide application prospects. A novel efficient skin care composition and an application scheme are provided for the field of cosmetics.

The utility model discloses a skin elasticity detection device which comprises a track base, the outer surface of the track base is sleeved with a movable seat in a sliding mode, the top of the movable seat is fixedly connected with a vertical rod, one side of the outer surface of the vertical rod is rotationally connected with a large arm, one side of the outer surface of the large arm is rotationally connected with a small arm, and the small arm is fixedly connected with the track base. One side of the outer surface of each small arm is rotationally connected with a connecting base, and locking assemblies are jointly installed between the vertical rod and the large arms, between the large arms and between the small arms and the connecting bases; and one side of the outer surface of the connecting seat is fixedly connected with a traction assembly. According to the skin detection device, the movable seat, the vertical rod, the large arm, the small arm, the connecting seat, the locking assembly, the traction assembly, the detection assembly and the vacuum pump are arranged, the whole skin detection device adopts a multi-connecting-rod structural design, and the position of the detection assembly can be correspondingly adjusted according to the position of a skin detection point to be detected of a detected person, so that the actual detection scene requirement is met, and the use effect is guaranteed.

The invention belongs to the technical field of cosmetics, and particularly discloses a cosmetic composition and eye cream for fading dark circles of eyes and a preparation method, the cosmetic composition is prepared from the following raw materials in parts by weight: 0.1-2 parts of Mailong eight-treasure raw powder, 0.1-2 parts of sialic acid, 0.1-5 parts of caffeine, 0.01-1 part of glucosyl hesperidin, 0.01-2 parts of mulberry root bark extract and 0.1-5 parts of botryine. The cosmetic composition provided by the invention can effectively improve the skin microcirculation around eyes, enhance the elasticity of the skin around eyes and reduce hyperpigmentation, so that dark circles around the eyes are obviously faded, and meanwhile, the cosmetic composition also has the advantages of small irritation and high safety; the prepared eye cream is high in stability and small in irritation; meanwhile, the whole process of the eye cream is simple, easy to implement and suitable for industrial production and application.

This needle assembly for a laser treatment directly radiates laser into skin by using a needle having an optical fiber inserted therein, and thus may effectively improve various skin problems such as elasticity, wrinkles, inflammation, and acne. In addition, local regional treatment is enabled so that side-effects resulting from the laser irradiation may be minimized and the pain of a subject being treated may be reduced. The needle assembly for a laser treatment comprises: a needle part comprising a hollow needle and a needle support part having one end portion of the needle passing therethrough and fixed therein; an optical fiber positioned inside the needle along the length direction such that one end of the optical fiber is not exposed to the outside of the tip portion of the needle; an optical fiber support part connected to the other end of the one end of the optical fiber; and a guide component positioned between the needle support part and the optical fiber support part so as to guide the insertion of the optical fiber into the hollow of the needle.

An anti-aging injection composition, an anti-aging injection, and use thereof. The anti-aging injection composition contains hyaluronic acid or a salt thereof, glycine, proline, lysine hydrochloride, and leucine, which can synergistically promote the generation of collagen and elastin in the skin, thereby helping to correct skin wrinkles, improve skin elasticity, and enhance skin radiance. The anti-aging injection composition can be used to prepare an anti-aging injection, which has the effect of resisting skin aging.

The invention relates to application of a fish maw and colla corii asini composition in preparation of anti-aging products, and belongs to the technical field of health-care products. The mass ratio of the fish maw to the colla corii asini in the fish maw and colla corii asini composition is (1-2): 1, and the colla corii asini is Dongshan colla corii asini powder. The fish maw and colla corii asini composition has the advantages that the anti-oxidation level, the collagen metabolism level and the cell function level are mutually cooperated, the anti-oxidation capability is obviously improved, the dermis layer is delayed to be thinned, the skin elasticity is effectively improved, and the anti-aging effect is achieved.

The invention discloses an anti-inflammatory and anti-aging composition as well as a preparation method and application thereof. The composition disclosed by the invention at least comprises one or more of lavender flower extract, carboxymethyl chitosan and hydrolyzed yeast protein. Compared with a single-component anti-inflammatory factor, the composition disclosed by the invention has a good effect; the product prepared from the composition has anti-inflammatory and anti-aging effects, can achieve the effects of removing redness, repairing skin barrier, increasing skin elasticity, improving skin brightness and improving skin grease, and is not only suitable for dry sensitive skin, but also suitable for oil sensitive skin.

To provide a novel skin visco-elasticity improver.SOLUTION: The invention for solving above mentioned problems provides: 1. a skin pure elasticity improver including as an active ingredient, a tomato seed extract; 2. a skin net elasticity improver including as an active ingredient, a tomato seed extract; 3. a skin return rate improver including as active ingredient, a tomato seed extract; 4. a skin visco-elasticity improver being described in any of 1-3; 5. a skin visco-elasticity improver including as an active ingredient, a tomato seed extract; 6. an AGE production restrainer including as an active ingredient, a tomato seed extract; 7. the tomato seed extract in the above 1. to 6. includes lycoperoside; and 8. the lycoperoside in the agent in the above 7 is the lycoperoside H.SELECTED DRAWING: None

A method for improving skin elasticity includes use of a composition containing an ethanol-extracted product of Aronia melanocarpa fruit and Bifidobacterium longum CB108 which is deposited at the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH under an accession number DSM 33895 in accordance with the Budapest Treaty.

The invention discloses a skin care efficacy evaluation method and system based on multi-modal data, and relates to the field of product efficacy evaluation, and the method comprises the steps: obtaining a plurality of skin detection reports of a plurality of users in laboratory detection equipment, and constructing a multi-modal skin data set according to the plurality of skin detection reports; wherein each piece of multi-modal skin data comprises acquisition time, acquisition environment temperature and humidity, skin moisture content, sebum content, skin elasticity, skin color and acne characteristics; correcting each piece of multi-modal skin data in the multi-modal skin data set based on the acquired environment temperature and humidity to obtain a first standard skin data set; based on the acquisition time, performing time sequence analysis on the first standard skin data set to obtain a skin classification result and an efficacy feature data set; based on a clustering algorithm, combining the skin classification result and the efficacy feature data set to construct an efficacy evaluation model; and according to the efficacy evaluation model, combining user test data of the skin care product to be evaluated to obtain an efficacy evaluation result.

The present invention relates to a composition comprising plant extracts. The composition according to the present invention has a skin whitening effect by reducing the total amount of melanin and tyrosinase activity in melanocytes of the skin, promotes skin regeneration and increases skin elasticity or reduces skin wrinkles by promoting collagen synthesis and inhibiting collagenase activity in fibroblasts of the skin, has an anti-inflammatory effect or a skin soothing effect by inhibiting NO generation, increases the amount of moisture in the skin and has a moisturizing effect by promoting generation of hyaluronic acid in fibroblasts, and has an antioxidant effect by scavenging free radicals. In addition, since the composition of the present invention exhibits a broad antibacterial effect against various bacteria, the composition may be used as a cosmetic composition, a pharmaceutical composition, a skin external preparation, or a food composition.

The invention discloses a golden triangular support anti-aging method. The method comprises the following steps: S1, barrier pretreatment; S2, active component delivery; S3, photocuring network shaping; according to the golden triangle support anti-aging method, synthesis and degradation balance of three core components of a skin extracellular matrix are synergistically regulated and controlled, and a golden triangle support system is formed. The small molecule peptide Pro-Hyp-Gly in the collagen activation component and the copper ion chelate act together, so that fibroblasts are promoted to secrete collagen, and the skin supporting force is enhanced; beta-aminopropionitrile serving as a lysyl oxidase inhibitor in the elastin protection component and vitamin E succinate have a synergistic effect, so that the degradation of elastin is inhibited, and the skin elasticity is maintained; the hyaluronic acid synergistic component is compounded by hyaluronic acid with different molecular weights to form a graded water locking network, so that the water content and plumpness of the skin are improved.

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

The application discloses a composition with long-acting anti-wrinkle, skin elasticity improvement and skin tightening effects, a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition comprises the following efficacy components: Schizosaccharomyces pombe ferment lysate, hydroxypropyl tetrahydropyrane triol, lactose, whey protein, lactic acid, Lactarius volemus extract and palm leaf tree extract. The eye cream prepared by using the composition has very significant long-acting anti-wrinkle, skin elasticity improvement and skin tightening effects. After 28 days of use, the R2 value of skin elasticity at the corner of the eye is increased by more than 20%, the R0 value of total skin stretching displacement is decreased by more than 40%, the proportion of wrinkle area is decreased by more than 15%, and the wrinkle depth is decreased by more than 27%. The effect after 28 days of use is also significantly better than that after 14 days of use.

This invention discloses a composition for fading dark spots, whitening, and firming the skin, and its preparation method, specifically belonging to the field of cosmetic technology. The composition contains extracts of *Bretschneidera sinensis* bark, hydroxypinazone 9-cis-retinate, sage lactone, tetrahydromagnoliol, and quercetin dimer. The composition provided by this invention can significantly reduce skin melanin content, improve skin brightness, and significantly improve skin elasticity and firmness. The synergistic effect of the components effectively achieves the effects of fading dark spots, whitening, and firming the skin. The preparation process provided by this invention is stable and controllable, suitable for large-scale production, and provides a novel and highly effective skincare composition and application solution for the cosmetic field.

The invention discloses a kind of penetration-promoting composition and its preparation method and application, belong to the field of cosmetic technology, the penetration-promoting composition, including the components of the following parts by mass: 0.5~8 parts of hydrolyzed sodium hyaluronate, 5~20 parts of stabilizers, 12~25 parts of yeast / rice fermentation product filtrate, 40~80 parts of solvents; the stabilizer includes decapeptide-4, soy lecithin, sodium carboxymethyl cellulose, polyethylene glycol surfactant in a mass ratio of (0.05~0.4): (0.05~0.4): (0.08~0.5): 1. The present invention, under the joint action of hydrolyzed sodium hyaluronate, stabilizer, yeast / rice fermentation product filtrate, from improving the antioxidant effect, stability, repairing skin barrier of composition, improving the moisturizing effect and skin elasticity of composition, effectively reducing surface tension, improving the permeability and wettability of liquid, destroying the permeability of cell membrane, on the basis of not destroying skin barrier, promoting effective ingredient to penetrate and reach the deep layer of skin, gently releasing effective ingredient, promoting skin to be effectively absorbed.

The invention belongs to the technical field of acupoint patches, and particularly relates to an acupoint patch acting on joints and a preparation method thereof.The acupoint patch comprises a breathable non-woven fabric, the front portion of the breathable non-woven fabric is coated with a medical adhesive layer and provided with a plurality of tearing cracks, the middle of the front side of the breathable non-woven fabric is connected with a cotton backing ring in an adhesive mode through the medical adhesive layer, and a medicine cake is arranged in the cotton backing ring; the medicine cake is prepared from the following components in parts by weight: 12 parts of notopterygium root, 12 parts of radix angelicae pubescentis, 12 parts of ramulus mori, 12 parts of pawpaw, 12 parts of rhizoma sparganii, 10 parts of ligusticum wallichii, 6 parts of cassia twig, 15 parts of angelica sinensis, 15 parts of kadsura pepper stem, 15 parts of salvia miltiorrhiza, 5 parts of frankincense, 5 parts of myrrh, 10 parts of cornu cervi pantotrichum and a proper amount of collagen peptide. By adding the cornu cervi pantotrichum and the collagen peptide, both the cornu cervi pantotrichum and the collagen peptide can effectively relieve arthralgia and improve joint flexibility, and meanwhile, the collagen peptide can maintain skin elasticity, promote wound healing and prevent skin damage to the position where a user uses the acupoint patch for a long time.

The present invention belongs to the technical field of medical preparations, and specifically relates to an anti-aging composition and a preparation method thereof. The anti-aging composition comprises the following raw materials in parts by weight: 5-10 parts bovine collagen tripeptide, 5-10 parts erythritol, 1-5 parts concentrated apple juice, 0.05-1 parts hydrolyzed collagen, 0.05-1 parts salmon powder, 0.05-1 parts fish maw oligopeptide, 0.05-1 parts golden bell fruit powder, 0.05-1 parts brown sugar powder, 0.05-1 parts albumin polypeptide, 0.05-1 parts sucralose, 1-5 parts anhydrous citric acid, and 55-90 parts purified water. The present invention not only supplements the collagen required by the human body, but also improves skin elasticity and scavenges free radicals.

The invention belongs to the technical field of cosmetics, and particularly relates to collagen peptide with an anti-aging effect as well as a preparation method and application of the collagen peptide. The amino acid sequence of the collagen peptide is as shown in SEQ ID NO.1, and the nucleotide sequence of the collagen peptide is as shown in SEQ ID NO.2. According to the invention, effective sequences of human III type and XVII type collagen are recombined to construct and express the collagen peptide Sa1, and the collagen peptide Sa1 has obvious antioxidant effect, no cytotoxicity and good safety. The skin care product added with the collagen peptide Sa1 can promote skin collagen absorption and effectively exert the anti-oxidation effect, so that the effects of improving skin elasticity and delaying skin aging are achieved.