162 results about "Blood loss" patented technology

The invention relates to a multi-parameter integration and AI fusion postpartum hemorrhage intelligent monitoring, prevention and control method and system. The method comprises the following steps: acquiring blood flow data; the blood flow data comprises blood loss volume and blood flow velocity, and the blood flow data is obtained through measurement of an optical fiber sensor; acquiring vital sign information; the vital sign information comprises blood pressure, heart rate and oxyhemoglobin saturation, and the vital sign information is obtained through continuous monitoring of a vital sign patch; according to the blood flow data, the vital sign information and the medical history information, a bleeding risk grade evaluation result is calculated in real time through an AI risk evaluation model, and the AI risk evaluation model is used for dynamically evaluating the bleeding risk; and triggering corresponding grading early warning according to the bleeding risk grade evaluation result, wherein the grading early warning is used for indicating bleeding risk processing. By adopting the method, the early warning accuracy and treatment efficiency of postpartum hemorrhage can be remarkably improved, and complications and death risks of pregnant and lying-in women are effectively reduced.

The invention features polypeptides that include an extracellular ActRIIA variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIA variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving low red blood cell levels, e.g., anemia or blood loss; fibrosis; or pulmonary hypertension.

Aspects of the disclosure provides composition and methods for treating a subject having a blood loss condition, the method comprising administering to the subject a hemojuvelin (HIV) antagonist (e.g., anti-HJV antibody).

The utility model discloses a thrombus aspiration plugging sheath system based on a special-shaped cavity, which comprises a vacuum device, an aspiration plugging sheath, an aspiration plugging sheath and an aspiration plugging sheath, and is characterized in that the vacuum device comprises a negative pressure needle cylinder and a piston buckle arranged on the side wall of the negative pressure needle cylinder; the balloon sheath tube comprises a tube body, a balloon used for blocking is arranged at the far end of the tube body, a connector connected with the vacuum device is arranged on the side of the near end of the tube body in a supporting mode, and a plurality of special-shaped cavities are formed in the tube body; the thrombus dragging instrument is used for blocking blood flow to reduce blood loss during thrombus suction and intercepting the thrombus to prevent the thrombus from escaping when the thrombus is dragged; the vacuum device is arranged on the side branch of the near end of the balloon sheath tube, and the thrombus dragging instrument is arranged in the balloon sheath tube. According to the embodiment of the utility model, the balloon filling opening and the thrombus suction opening are formed in the catheter body, a multi-cavity structure is adopted, the balloon sheathing canal blocks blood flow, and the thrombus dragging instrument is matched with a vacuum device to suck, drag and take out thrombus.

A stretcher including a flexible base panel sized to support a person lying thereon during a rescue or extrication operation. The base panel includes a header end and an opposite footer end, and further includes a plurality of securement straps, a shoulder harness, and a leg harness coupled to the base panel to help restrain the injured person and prevent further injury that may be caused such as by having the person roll off the sides of the stretcher. The leg harness may be configured to function as a junctional tourniquet to minimize blood loss at the pelvic region in the case of severe injury to the person.

The invention relates to the technical field of postoperative rehabilitation. The spine postoperative intelligent nutrition management method comprises the steps of performing multi-modal data fusion processing based on preoperative sign data, intraoperative blood loss and fluid loss amount and postoperative biochemical indexes of a patient to generate personalized nutrition requirement parameters; performing real-time monitoring and comparison processing on the postoperative diet intake of the patient through intelligent tableware provided with a weight sensor and an image recognition module according to the personalized nutritional requirement parameters, and generating a nutritional intake dynamic map; performing dynamic deviation analysis processing on detection data of the bioelectrical impedance analysis equipment and the saliva biomarker sensor to generate nutrition metabolism feedback data; and fusing the nutrition intake dynamic spectrum and the nutrition metabolism feedback data, carrying out nutrition intervention scheme optimization processing through a reinforcement learning model, generating a dynamic adjustment instruction, and pushing the instruction to a terminal, so as to achieve the technical effects of adapting to individualized requirements, tracking a metabolism state in real time and balancing nutrition intervention accuracy and safety.

A networking-capable emergency tourniquet including an adjustable and inflatable cuff configured to encircle a limb of a patient, and a controller unit removably coupled to the inflatable cuff. The controller unit includes a microcontroller configured to control the introduction, removal, and maintenance of air within the inflatable cuff and process collected patient data, a communicator unit configured to communicate with the user, a transmitter configured to transmit the collected patient data to a centralized server over a communication network, and a receiver configured to receive information from at least one of the centralized server and other sources over the communication network.

The utility model relates to a blood pumping catheter and a ventricular assist system.The blood pumping catheter comprises a perfusion cavity, a perfusion pipeline, an elastic element and a first flow adjusting component, the far end of the perfusion pipeline is connected to the perfusion cavity, the elastic element and the first flow adjusting component are both installed on the perfusion pipeline, and the first flow adjusting component is located between the elastic element and the perfusion cavity; the first preset value is larger than or equal to zero, and the first flow adjusting component is in a cut-off state under the condition that the difference value between the near-end-side pressure of the first flow adjusting component and the far-end-side pressure of the first flow adjusting component is smaller than the first preset value. According to the embodiment of the invention, the blood loss of a patient can be reduced, and the risk of thrombus formation and blockage in the perfusion device and the blood pumping catheter is reduced, so that the operation stability and the operation life of the perfusion pipeline on the near end side of the perfusion device and the blood pumping catheter can be relatively improved.

The invention features polypeptides that include an extracellular ActRIIA variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIA variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving low red blood cell levels, e.g., anemia or blood loss; fibrosis; or pulmonary hypertension.

The invention relates to the technical field of medical instruments, and provides a hemostasis valve structure and a sheathing canal assembly, and in the hemostasis valve structure, a valve body assembly is connected with a sheathing canal body. The two ends of the annular bag body are connected with the valve body assembly respectively, the middle of the annular bag body naturally droops, and the annular bag body is of a flexible inelastic bag body structure. And the liquid filling assembly is communicated with the annular bag body. When no instrument passes through the sheathing canal body, liquid is filled into the annular bag body through the liquid filling assembly, so that the annular bag body is expanded until the annular bag body is completely closed, and the sealing effect is achieved. When an instrument needs to be arranged in the sheathing canal body in a penetrating mode, liquid in the annular bag body does not need to be discharged, and the instrument can directly penetrate through the annular bag body in the expanded state. On one hand, operation is time-saving and labor-saving; on the other hand, due to the fact that the annular bag body is in the expansion state all the time, blood cannot flow out between the instrument and the annular bag body, and the blood loss risk is avoided.

The application discloses a kind of thrombus suction control method and thrombus suction device, and thrombus suction device includes suction assembly, suction assembly includes the shell with pressure cavity, piston rod and suction catheter, thrombus suction device also includes the motor of piston rod movement and the controller connected with motor, control method is: suction catheter is positioned to the blood vessel without thrombus, make motor operate according to speed V0, calibrate the pressure value B in pressure cavity under normal blood condition;Suction catheter is positioned to the blood vessel with thrombus, make motor operate according to speed V1, V1≤V0, make dynamic pressure value A0 in pressure cavity: when A0≤B, make motor keep speed V1 operation;When A0>B, make motor increase from speed V1: when B<A0≤C, make motor increase to speed V2 operation;When C<A0≤D, make motor increase to speed V3 operation;When D<A0≤E, make motor increase to speed V4 operation.The control method thrombus removal efficiency is high, and blood loss can be reduced.

The invention provides a carotid artery thrombus treatment catheter and a suction system comprising the same, and belongs to the technical field of medical instruments. The treatment catheter comprises a catheter body, a blocking balloon, a balloon pressurizing cavity and a Luer connector. The suction system comprises a Y-shaped connector, a blood transfusion module and a pressure monitoring system. Gapless wall attachment of the blood vessel wall is achieved through the blocking balloon, thrombus residues are avoided, suction-instrument conveying integrated operation is achieved in cooperation with the Y-shaped connector, and the multi-instrument exchange process is simplified; the balloon pressurizing cavity can accurately control the plugging balloon to expand to block blood flow, and thrombus fragments are prevented from being migrated; the peristaltic pump and the filter assembly of the blood transfusion module are connected through the catheter inner cavity, thrombus is sucked, filtered blood is transfused back, blood loss is reduced, the hemolysis risk is reduced, and the technical problems of thrombus residues, large blood loss amount, tedious operation, insufficient safety and the like are solved. The thrombus is efficiently removed, blood loss is remarkably reduced, the process is simplified, and the treatment safety is guaranteed through pressure monitoring.

This invention discloses a method for preparing a composite spray that improves hemostasis at wound sites. The composite spray includes solution A and solution B, where solution B is an aqueous solution of sodium alginate. The preparation method of solution A includes: 1. Dissolving a lipopeptide conjugate, cholesterol, distearylphosphatidylcholine, distearylphosphatidylserine, and dimethyl sulfoxide in a chloroform-methanol mixed solution to obtain a mixed system; 2. Preparing a precursor solution from the mixed system using a thin-film hydration method; 3. Adding calcium chloride to the precursor solution and reacting it in the dark to obtain solution A. This invention designs the precursor solution based on the function of natural platelets, and its function is equivalent to that of nanoplatelets. Combined with sodium alginate, it can specifically alleviate the adverse effects on the coagulation system caused by blood loss, such as fibrin degradation and reduced platelet activation, at wound sites. It has the characteristics of rapid hemostasis, good bioactivity, and rapid wound healing.

An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.

The application discloses a prosthesis system for minimally invasive femoral head replacement, which comprises a bone cutting assembly, a prosthesis, an extension rod, a guide frame and a locking nail. In the operation, only a small opening is needed on the lateral side of the femoral neck, and then a channel is established, and the prosthesis is implanted in the channel, so that the degree of trauma, the operation time and the blood loss are greatly reduced. A detachable extension rod is arranged on the implanted prosthesis, and after the extension rod is positioned by cooperating with the guide frame, the extension rod can guide the path of the locking nail, so that the locking nail is connected with the prosthesis, and is fixed with the large and small trochanters of the patient, so that the prosthesis can be combined with the relatively hard bone and the surface layer of the femoral neck to achieve stable combined support and avoid loosening of the prosthesis.

FIELD: otorhinolaryngology.SUBSTANCE: under endotracheal anesthesia, an endoscope equipped with optics and an instrument for removing pathological contents of the maxillary sinus are inserted into the nasal passage. The inferior nasal concha is displaced medially using a raspatory. Then, stepping back from the edge of the piriform opening by 1.5–2.0 cm in the caudal direction, a mucoperiosteal flap of the lateral wall is separated in the lower nasal passage. The mucoperiosteal flap is displaced posteriorly, exposing the bone skeleton in the projection of the inferomedial angle of the maxillary sinus. Next, using a cold plasma coblator, in ablation mode, the mucous surface of the bone skeleton is evaporated for 2–3 seconds, followed by coagulation of small vessels. Then, a bone valve measuring 10–15 mm is formed from the exposed bone skeleton. The bony valve is retracted in the caudal direction, forming an antrostomy. A 70-degree endoscope is inserted through the formed antrostomy and the pathological contents of the sinus are visualized. In this case, if the cyst is visualized with a coblator in ablation mode, the cyst is evaporated along with its contents, and the remaining cyst is captured and removed. If a polyp is visualized, the polyp stalk is first evaporated, and then the remaining part of the polyp is removed. If a foreign body is visualized, it is removed with forceps. In this case, if the foreign body is encapsulated or located in the thickness of the mucosa, a coblator in ablation mode evaporates part of the mucosa until the foreign body is exposed, and then removed. Next, the sinus cavity is washed with saline solution. The antrostomy is closed with a bone flap. The formed mucoperiosteal flap is placed back in its original place.EFFECT: method allows for endoscopic endonasal removal of pathological contents from the maxillary sinuses with a minimal risk of cyst / polyp recurrence and postoperative complications, reduced blood loss during surgery, shortened surgical time, postoperative rehabilitation periods, and temporary disability.3 cl, 3 ex

The invention features polypeptides that include an extracellular ActRII chimera. In some embodiments, a polypeptide of the invention includes an extracellular ActRII chimera fused to an Fc domain or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness or atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), low platelet levels (e.g., thrombocytopenia), low neutrophil levels (e.g., neutropenia), fibrosis, metabolic disorders, pulmonary hypertension, and / or diseases and conditions that can be treated with erythropoietin or an erythropoiesis-stimulating agent.

The invention belongs to the technical field of drainage devices, and discloses a pericardial effusion drainage device which comprises an extracorporeal membrane lung oxygenation therapeutic apparatus and a fixing device. The extracorporeal membrane lung oxygenation therapeutic apparatus comprises a main control table, an artificial membrane lung, a centrifugal pump and an oxygenator, an inlet and an outlet of the centrifugal pump are connected with a first catheter and a second catheter respectively, the first catheter is connected with veins of a patient, the free end of the second catheter is connected with the artificial membrane lung, the artificial membrane lung is connected with a third catheter, and the third catheter is connected with the oxygenator. The free end of the third catheter is connected with the artery or vein of the patient; a branch tube of the first catheter is connected with a hydrops catheter, the free end of the hydrops catheter is connected with a drainage tube, and the diameter of the hydrops catheter is smaller than that of the drainage tube. The technical problems that according to an existing drainage mode, effusion cannot be continuously drained, the drainage efficiency is low, the postoperative anemia risk can be increased for a patient with blood loss due to an operation, and the recovery cycle of the patient is prolonged are solved.

The dialysis catheter replacement connector comprises a flow divider, a first catheter, a second catheter and a third catheter, one end of the first catheter and one end of the second catheter are communicated with one end of the third catheter through the flow divider, and the other end of the first catheter is provided with a one-way valve used for inserting a guide wire. The other end of the second catheter is provided with a second catheter connector used for being connected with a radiography syringe, and the third catheter is provided with a third catheter connector used for being connected with the shearing opening of the built-in catheter. According to the dialysis catheter replacement tube connector, radiography and placement of a guide wire into the body of a patient can be conducted at the same time, operation of a doctor is facilitated, operation risks are reduced, and medical safety is improved; the catheter infection probability in the catheter replacement process can be further reduced; the blood loss of a patient can be reduced, the surgical tolerance of the patient is improved, and the postoperative recovery time is prolonged; the medical experience of the patient can be improved, and the satisfaction degree of the patient is improved.

The present application relates to a protection system, which comprises: at least one protection sheath, which comprises an outer sheath tube and a filter arranged at the distal end of the outer sheath tube; the outer sheath tube has a first lumen, and the filter has a proximal opening and a distal opening, the distal opening is communicated with the first lumen through the proximal opening; a filter bypass device, which has an input port and an output port, the input port is communicated with the first lumen; at least one return tube, the proximal end of the return tube is communicated with the output port, and the distal end of the return tube is used for returning the filtered blood to the human body. The protection system of the present application can protect the branch blood vessels during the expansion of the branch stent, and can return the filtered blood to the human body, thereby reducing the blood loss of the patient during the operation.

In an illustrative embodiment, methods and systems for treating uterine bleeding include applying, at least every other day in which a subject exhibits or is expected to exhibit menstrual bleeding, neurostimulation therapy in one or more sessions, each session having a duration of at least five minutes, the neurostimulation therapy including applying electrical neurostimulation or mechanical neurostimulation to directly and / or indirectly activate one or more neural targets, the one or more neural targets including a trigeminal cervical complex and / or vagal efferent fibers. The neurostimulation therapy may be configured to enhance platelet function of the subject, thereby reducing a total volume of blood loss over a course of the menstrual bleeding.

The invention discloses a device and method for removing a contrast agent in heart local blood, and relates to the field of medical treatment, the removing device comprises a suction catheter, a power pump, a filter assembly and a backflow catheter which are connected in sequence; the coronary artery of the heart body is communicated with the angiographic catheter, the coronary sinus of the heart body is communicated with the suction catheter, the femoral vein or other deep veins of a human body are communicated with the backflow catheter, and the area between the coronary artery and the coronary sinus is a contrast agent delivery area; wherein the filtering assembly is used for removing a contrast agent in blood. When the contrast agent in the blood is removed, the blood containing the contrast agent is pumped out of the heart body through the suction catheter by the power pump, then the contrast agent contained in the blood is removed through the filtering assembly, and then the blood without the contrast agent is conveyed into the human body again through the femoral vein or other deep veins by the backflow catheter. By means of the circulating conveying mode, on one hand, contrast agents in blood can be removed, and on the other hand, excessive blood loss of a patient can be avoided.

The invention relates to the technical field of rapid hemostasis application, in particular to a rapid compression hemostasis device which comprises a compression hemostasis block, two positioning clamping belts and an elastic buckling belt, and the rapid compression hemostasis device not only conducts physical compression hemostasis on a wound through the compression hemostasis block, but also combines the function of medicine hemostasis. The compression ring in the compression hemostasis block can accurately compress the periphery of a wound, the bleeding amount is reduced, the medicine block enables hemostasis medicine to directly act on the wound through the medicine penetrating layer, and the hemostasis effect is enhanced. In a battlefield or an emergency medical scene, bleeding can not be completely controlled by purely relying on compression hemostasis, but the hemostasis efficiency can be remarkably improved and the blood loss risk can be reduced by adding the medicine. In addition, due to the design of the cotton ring and the medicine permeating layer of the medicine block, air permeability of the wound can be kept, it can be guaranteed that medicine continuously acts on the wound, and wound oxygen deficit or infection caused by too tight compression is avoided.

This application discloses a nutritional meal recommendation system, method, equipment, and medium for post-gynecological surgery, relating to the field of digital health management technology and applied to a computer device. It includes: an association matrix acquisition module, used to construct dynamic physiological signs by combining the patient's hormone levels and blood loss after gynecological surgery, and splicing them according to time sequence and the nutritional ratio of candidate ingredients to generate a nutritional metabolism association matrix; an evolution matrix acquisition module, used to perform first-order differentiation and normalization of the matrix in the time dimension to construct a metabolic nutritional evolution feature matrix; a node sequence construction module, used to split feature vectors, construct a heterogeneous graph using gastrointestinal dynamic impedance, and use a graph attention network to screen ingredient nodes to form a sequence of nodes with absorption potential; and a meal plan generation module, used to calculate the nutritional difference in the sequence, extract decreasing topological fragments, and generate an individualized nutritional meal plan adapted to the patient's dynamic physiology and gastrointestinal capacity.

In an illustrative embodiment, methods and systems for treating uterine bleeding include applying, at least every other day in which a subject exhibits or is expected to exhibit menstrual bleeding, neurostimulation therapy in one or more sessions, each session having a duration of at least five minutes, the neurostimulation therapy including applying electrical neurostimulation or mechanical neurostimulation to directly and / or indirectly activate one or more neural targets, the one or more neural targets including a trigeminal cervical complex and / or vagal efferent fibers. The neurostimulation therapy may be configured to enhance platelet function of the subject, thereby reducing a total volume of blood loss over a course of the menstrual bleeding.

The invention features polypeptides that include an extracellular ActRII chimera. In some embodiments, a polypeptide of the invention includes an extracellular ActRII chimera fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), low platelet levels (e.g., thrombocytopenia), low neutrophil levels (e.g., neutropenia), fibrosis, metabolic disorders, and / or pulmonary hypertension.

The utility model discloses a postpartum hemorrhage nursing device convenient for metering the hemorrhage amount. The postpartum hemorrhage nursing device comprises a waterproof pad, a catheter and a blood collecting bottle, the upper end face of the waterproof pad forms a liquid guide slope surface which is obliquely arranged towards the lower rear portion, a left liquid blocking protection edge A is arranged on the liquid guide slope surface from the left middle portion to the rear middle portion of the liquid guide slope surface, a right liquid blocking protection edge A is arranged on the liquid guide slope surface from the right middle portion to the rear middle portion of the liquid guide slope surface, and a liquid drainage groove is formed between the rear end of the left liquid blocking protection edge A and the rear end of the right liquid blocking protection edge A; the first end of the catheter is connected to the drainage groove, and the second end is connected to the top of the blood collection bottle; the outer wall of the blood collection bottle is provided with containing marks. The beneficial effects of the utility model are that under the diversion of the drainage slope and the guidance of the left and right liquid-blocking protective edges A, the blood from the private part of the puerpera after delivery can be drained to the drainage groove and flows to the blood collection bottle along the drainage tube, and medical staff can estimate the bleeding amount by observing the volume scale corresponding to the liquid level of the collected blood, so that the physical state of the puerpera can be evaluated conveniently; therefore, a doctor can diagnose and treat the body of the puerpera.

An access sheath and method of assembling the access sheath. The access sheath includes a hub, a cartridge carried by the hub, the cartridge having a first valve, a second valve spaced from the first valve along a central axis, and a spacer disposed between the first valve and the second valve, wherein the first valve and the second valve each have at least two slits that extend along, and twist about, the central axis, and a shaft assembly having a shaft hub and a shaft that extends from the shaft hub in the distal direction. The access sheath provides a liquid-tight seal when receiving the introducer and other devices to prevent leakage and blood loss and to decrease device insertion forces.

The application provides a myocardial perforation repair cover and belongs to the field of medical devices. The cover body is sealed outside the pericardium, and a liquid inlet pipe, a liquid outlet pipe and a plurality of operation valve ports are arranged in the cover body. The edge of the cover body is tightly sutured on the pericardium to form a closed operation space. A video rod and a suturing instrument are arranged in the operation space through the valve ports. The video rod can obtain a clear visual field in the operation space through the flushing of the liquid inlet pipe and the liquid outlet pipe at the sutured position, and the suturing instrument is used to suture the myocardial perforation. The application avoids the direct opening of the myocardial perforation, reduces the risk of rapid blood loss through the perforation, recovers the lost blood, greatly reduces the risk of the myocardial perforation repair operation and greatly improves the cure rate.