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198 results about "Electrode array" patented technology

An electrode array is a configuration of electrodes used for measuring either an electric current or voltage. Some electrode arrays can operate in a bidirectional fashion, in that they can also be used to provide a stimulating pattern of electric current or voltage.

A method for preparing a transparent microelectrode array chip

The present application relates to the technical field of microelectrode preparation, and particularly relates to a transparent microelectrode array chip preparation method, comprising the following steps: S1. pretreating a glass substrate to improve the substrate surface cleanliness and adsorbability of the electrode film; S2. evaporating an ITO film on the surface of the pretreated glass substrate by using a magnetron sputtering process, as a transparent electrode; S3. spin-coating a photoresist on the surface of the ITO film and performing a patterning treatment, and then etching the ITO film to form a preset electrode structure by using a dry etching process, and then removing the photoresist and cleaning and drying; S4. coating an insulating layer on the surface of the substrate by using a PECVD process, patterning the insulating layer and etching by using a dry etching process to realize windowing, and then removing the photoresist and cleaning and drying; and realizing photoelectric synchronous detection. Avoiding metal residue interference: photoresist masks are used throughout the etching process to replace traditional metal hard masks.
Owner:WESTLAKE INSTITUTE FOR OPTOELECTRONICS

3D microelectrode arrays (3D meas) with multiple sensing capabilities for the investigation of electrogenic cells

A three-dimensional (3D) microelectrode array device for in vitro electrophysiological applications includes a substrate and micro vias extending from the bottom face to the top face of the substrate. A microneedle at each micro via extends from the bottom face upward beyond the top face and forms a hypodermic microneedle array on the top face. Metallic traces on the bottom face interconnect the hypodermic microneedles to form the 3D microelectrode array. A microheater is positioned on the bottom face of the substrate. Microfluidic ports may be formed at the substrate. Interdigitated electrodes may be formed at the substrate.
Owner:UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC

Deposition apparatus based on programmable electrode array and method of patterning deposition

The application discloses a deposition device based on a programmable electrode array and a patterning deposition method, which comprises the following steps: generating charged particles and / or mist droplets by a charged particle source; an insulating substrate comprises a front surface for receiving deposition and a back surface opposite to the front surface; a programmable electrode array is arranged on the back surface of the insulating substrate and used for guiding the deposition of the charged particles and / or the mist droplets; a voltage driving unit is used for providing independent voltage signals for the electrode unit, and the voltage signals are pulse signals or direct current signals; and a control unit is used for programming and controlling the output of the voltage driving unit according to a target pattern, so that the programmable electrode array forms a spatial electric field corresponding to the target pattern on the front surface of the insulating substrate. Through the deposition device based on the programmable electrode array and the patterning deposition method, any pattern can be generated and changed instantly through programming of an electric field, and a physical mask is replaced by an electric mask, so that the physical mask is not needed, and the flexibility is extremely high.
Owner:HUAZHONG UNIV OF SCI & TECH

Tunnel hole induced polarization device

The tunnel hole induced polarization device comprises a plurality of electrodes divided into a plurality of electrode arrays; a power supply control module provides different currents to the plurality of electrode arrays; a voltage sampling module collects potential differences generated by the tunnel hole induced polarization of the plurality of electrode arrays; a collection module collects the potential differences and converts and transmits the potential differences to an upper computer and converts and transmits instructions of the upper computer to a driving control module; the driving control module drives the power supply control module and the voltage sampling module respectively, the power supply control module comprises a power supply bus and a power supply relay array; an electromagnetic shielding module is arranged on the power supply relay array and is used for suppressing transient electromagnetic interference of a coil and electromagnetic interference of a switch contact.
Owner:SHANDONG UNIV

Permanent antistatic pc material preparation system

PendingCN122299882ATemperature controlElectrical impedance tomography
This invention provides a permanent antistatic PC material preparation system, comprising a mixing unit, an extrusion granulation unit, and an injection molding unit connected in sequence. The injection molding unit includes a barrel, a screw assembly rotatably disposed within the barrel, and an ERT sensor disposed at a nozzle at the end of the barrel. The ERT sensor includes an electrode array for online acquisition of electrical impedance tomography (EIT) data of the melt passing through the nozzle. The screw assembly includes a screw spindle with a longitudinally penetrating internal heat conduction oil channel. This internal heat conduction oil channel is connected to an external temperature control system via a connector. One section of the barrel is a compression section. A segmented thermal response sleeve is fitted around the outer periphery of the screw spindle within the compression section. The outer surface of the thermal response sleeve is provided with an outer peripheral conveying spiral. The thermal response sleeve responds to changes in the fluid temperature within the internal heat conduction oil channel by generating radial expansion displacement, thereby dynamically adjusting the compression ratio by changing the effective root diameter of the screw assembly within the compression section.
Owner:扬州集飞新材料科技有限公司

System and method for measuring human milk production

ActiveCN117769351BBioimpedance spectroscopyElectrode array
A breast milk flow monitoring system in the form of a milk flow monitoring sensor is described and includes an electrode array and a controller. The electrodes include electrically conductive surfaces arranged to contact a skin surface of a breast. The controller generates a first excitation signal delivered via a first electrode to a first location on the breast and generates a second excitation signal delivered via the first electrode to the first location on the breast. The controller receives a first current response signal and a second current response signal. A bioimpedance spectroscopy analysis of the first current response signal and the second current response signal is performed, where the bioimpedance spectroscopy analysis is calibrated for breast milk flow. A breast milk flow parameter is determined based on the bioimpedance spectroscopy analysis.
Owner:NFANT LABS LLC

Brain-computer interface system

PendingCN122075003Aeliminate relative motionsolve the lossSensorsDiagnostic recording/measuringCerebral meningesRight superficial temporal artery
The invention relates to a brain-computer interface system which comprises a flexible electrode array, a receiving device, a flexible connecting wire and external equipment, wherein the flexible electrode array is implanted into a meninx middle artery in a minimally invasive manner through a superficial temporal artery puncture and a vascular intervention procedure; the receiving device is embedded under the skin of a head and is provided with a signal transmitter; the external equipment is provided with a signal receiver. A flexible electrode array is implanted in an anterior branch or posterior branch of a main branch of a middle meninx artery through a superficial temporal artery intravascular minimally invasive technology, the number of electrodes and the array are arranged according to needs, and a receiving device buried in the subcutaneous part of the head is electrically connected with the flexible electrode array implanted in the middle meninx artery. Craniotomy is not needed, operative complications are avoided, minimally invasive implantation reaches the surface of the cerebral cortex, operation of a doctor is easier, the operation time is shortened, and the comfort level of a patient is improved.
Owner:HANGZHOU MATRIX MEDICAL TECH CO LTD

Electrode arrays for electroporation, and related systems and methods

Providing an electrode array for electroporation, as well as related systems and methods. [Solution] An electrode array for use with an electroporation device includes a support member having an upper surface and a bottom surface, defining a plurality of injection channels extending from the upper surface to the bottom surface. The plurality of needle electrodes are coupled to the support member such that the distal ends of the plurality of needle electrodes extend to a needle depth below the bottom surface. The plurality of needle electrodes are arranged in a matrix pattern having rows and columns of needle electrodes arranged along the support member. The plurality of injection channels are dispersed within the matrix pattern.
Owner:INOVIO PHARMACEUTICALS INC

Paresthesia-Free Spinal Cord Stimulation Occurring at Lower Frequencies Involving Perception Threshold Determinations

Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which a stimulation location in an electrode array is determined. Preferably, the supra-perception stimulation comprises a bipole formed using actively-driven symmetric biphasic waveforms at active ones of the electrodes in the array. After determining the location, a perception threshold for the bipole at the location is determined and stored, and an amplitude of the stimulation is reduced below the perception threshold to provide a sub-perception stimulation bipole. The determined perception threshold may be transmitted to the patient's remote controller, where it is used to limit amplitude adjustments to the sub-perception bipole by the patient.
Owner:BOSTON SCI NEUROMODULATION CORP

Transcutaneous spinal cord stimulation system and methods

PendingUS20260175041A1External electrodesPain managementElectrode array
Systems, methods, and devices disclosed herein include a transcutaneous spinal cord stimulation (tSCS) system with a stimulation electrode grid. The stimulation electrode grid includes a plurality of anodes and a plurality of cathodes, and the stimulation electrode grid is operable for placement proximate to a spinous process. The system also includes a particularized electrical field generated by selective activation of the stimulation electrode grid. Moreover, a localized tSCS, provided by the particularized electrical field is operable to cause a neuromodulation effect. Also, the stimulation electrode grid includes a substrate material. The plurality of cathodes and the plurality of anodes are both arranged as rows or columns on the substrate material to form an integrated unit. The stimulation electrode grid includes a plurality of selectively activated electrode array activation configurations, and the neuromodulation effect generated by the system can be used to enhance voluntary extremity function and pain management.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Methods of operating electrochemical-additive manufacturing systems comprising modular cartridge assemblies

Described herein are methods of operating ECAM systems comprising modular cartridge assemblies. A modular cartridge assembly comprises a base, a cover, an ECAM printhead, a support unit, and a control board. The base has an opening providing access to the support unit (e.g., for heat transfer and fluidic connections), which is sealed against the base around this opening. The cover also has an opening exposing the electrode array of the ECAM printhead. The ECAM printhead is also sealed against the cover around this opening. The control board selectively activates the electrode of the array and is positioned within a cavity formed by the base and cover. The modular cartridge assembly allows replacing the ECAM printhead when the electrode array is damaged (e.g., dissolved during the ECAM process), while other assembly components can be reused. Furthermore, the support unit provides alignment and heat transfer for the ECAM printhead.
Owner:FABRIC8LABS INC

Finite element model of current density and electrical impedance tomography based method for functional electrical stimulation

Systems and methods for generating a finite element model (FEM) of current flow in an anatomical human forearm are disclosed. The disclosed FEM may assist in determining optimal stimulation parameters in electrical stimulation systems for achieving movement of paralyzed limbs or enhancement of able limbs. This model will allow users to determine which muscle groups are receiving stimulation under different parameters. Systems and methods which leverage electrical impedance tomography (EIT) for autonomous recalibration following garment donning are also disclosed. The method may comprise performing an EIT measurement across an electrode array of an electrode garment and constructing an anatomical model based on the EIT measurement. Next, one or more alignment variations may be estimated based on an alignment variation model. Finally, the electrode array is adjusted, automatically or manually, to accommodate the alignment variations using an alignment adjustment function.
Owner:BATTELLE MEMORIAL INST

A method and apparatus for activating polarization of large-area ferroelectric capacitors at the wafer level

PendingCN122318223ACapacitanceFerroelectric thin films
This invention discloses a method and apparatus for awakening the polarization of a large-area ferroelectric capacitor at the wafer level. The wafer consists of a bottom electrode, a ferroelectric layer, and a patterned, independent top electrode array stacked sequentially from bottom to top. The bottom electrode is electrically connected to one end of a pulse voltage generator, and the conductive film on the surface of a flexible conductive roller is electrically connected to the other end of the pulse voltage generator. By controlling the horizontal movement of the wafer stage, the flexible conductive roller is driven to roll and contact the surface of the top electrode array; simultaneously, a preset pulse voltage is applied between the bottom electrode and the conductive film using the pulse voltage generator, increasing the ferroelectric remanent polarization intensity of the ferroelectric film covered by the top electrode in the contact area, thus achieving ferroelectric polarization awakening. This invention, after a high-temperature heat treatment at over 200°C, efficiently and over a large area awakens the polarization of the ferroelectric film corresponding to the top electrode array, ensuring high stability and consistency in its ferroelectric remanent polarization intensity.
Owner:NANJING UNIV OF SCI & TECH

Method for detecting electrical parameters of dielectric sheet of electrode array

The invention provides an electrical parameter detection method of a dielectric sheet of an electrode array, which is applied to a detection device with a conductive sheet, a conductive solution is configured in the detection device, and the detection method is characterized by comprising the following steps: step 1, placing a to-be-detected electrode array, a sufficient conductive solution is filled between each dielectric sheet and each conductive sheet of the to-be-detected electrode array; 2, the electrode array to be detected and the detection device are externally connected with a test instrument at the same time, so that the electrical parameters of the corresponding dielectric sheets are obtained. According to the test method, the electrical parameters of the dielectric sheet of the electrode array can be accurately detected, and nondestructive detection can be realized.
Owner:JIANGSU HEALTHY LIFE INNOVATION MEDICAL TECH CO LTD

Rockfall structure surface dynamic damage identification method based on resistance distribution state

The application discloses a dangerous rock mass structure surface dynamic damage identification method based on resistance distribution states, relates to the technical field of dangerous rock mass collapse monitoring and early warning of rock-soil slopes, and comprises the following steps: arranging electrode arrays on the two sides of the junction of a test dangerous rock mass and a stable bedrock; the electrode arrays comprise a group of power supply electrodes and multiple measuring electrodes; simulating the structure surface damage expansion process of the test dangerous rock mass based on a ladder type damage loading mode, and obtaining a dangerous rock mass crack damage factor in the structure surface damage expansion process; obtaining resistivity data corresponding to the structure surface damage expansion process based on the electrode arrays; constructing a damage-resistivity correlation model based on the dangerous rock mass crack damage factor and the resistivity data; and identifying the damage of the structure surface of a dangerous rock mass to be identified based on the damage-resistivity correlation model. The application alleviates the technical problem that hidden structure surface damage cannot be accurately captured in the prior art.
Owner:UNIV OF SCI & TECH BEIJING

Remote touch screen film based on a sharp discharge mechanism

This application relates to the field of electrical engineering, specifically to touchscreens. A long-distance touchscreen film based on a tip discharge mechanism includes a touch film having a dielectric layer as a substrate and electrode arrays arranged on both sides of the dielectric layer, namely a first electrode array and a second electrode array, and a plastic substrate. At least two sets of tip discharge arrays, namely a first tip discharge array and a second tip discharge array, are embedded in the plastic substrate. Each tip discharge array includes at least two tip discharge electrodes, each having a large end and a small end. The small end of the tip discharge electrode is located in the direction away from the dielectric layer on the plastic substrate. The capacitive touchscreen optimizes touch sensitivity by using a plastic substrate and tip discharge arrays, enabling the capacitive touchscreen system to detect weak capacitance changes when a finger or conductor approaches but does not directly contact the screen, supporting hover touch when the finger is not in contact with the screen.
Owner:WENZHOU HONGDA NEW MATERIAL TECHNOLOGY CO LTD

Integrated flexible pressure gait monitoring system and preparation packaging method

The application discloses an integrated flexible pressure gait monitoring system and a preparation packaging method, relates to the technical fields of wearable flexible sensing and gait monitoring, and comprises a flexible array distributed pressure sensor, a miniaturized signal acquisition circuit module, a battery module and special shoes. The flexible array distributed pressure sensor comprises, from top to bottom, a pressure-sensitive layer, an adhesive layer and a flexible electrode which are laminated in sequence, the flexible array distributed pressure sensor is in the shape of an insole and is laid flat on the inner surface of the shoe sole of the special shoes, the miniaturized signal acquisition circuit module is electrically connected with the flexible electrode, and the battery module is electrically connected with the miniaturized signal acquisition circuit module. The application adopts the above-mentioned integrated flexible pressure gait monitoring system and preparation packaging method, improves product consistency and facilitates large-scale production; the interdigital electrode array greatly improves the plantar pressure resolution and can accurately capture local pressure abnormalities; the integrated microcircuit and the special shoes realize wireless transmission and convenient wearing.
Owner:XI AN JIAOTONG UNIV

Deep learning based continuous and parallel electrical method intelligent monitoring system

The present application relates to the technical field of mine geophysical monitoring, in particular to a continuous parallel electric method intelligent monitoring system based on deep learning; the underground monitoring hardware system realizes full-field synchronous acquisition by parallel electric method AM / ABM mode through monitoring master station, substation and electrode array, and overcomes the defects of traditional high-density electric method; the underground acquisition control software and the uphole control processing module trigger acquisition and archiving regularly, form continuous data sequence, and meet the long-period monitoring demand; the intelligent inversion model is ERT-TransNet, the input embedded layer of which maps point cloud sequence, the encoder extracts global features, the decoder outputs predicted resistivity, realizes end-to-end mapping, avoids boundary ambiguity, improves boundary definition and positioning accuracy, and single sample prediction only needs 0.2 seconds, realizes efficiency order of magnitude improvement, and meets real-time processing demand.
Owner:CHONGQING UNIV

Sensor, device and related methods for signal synchronous acquisition of cardiomyocytes

The application relates to the technical field of electrophysiological detection, in particular to a sensor for synchronous acquisition of myocardial cell signals, a device and a related method, the sensor comprising a first control module, a second control module and a sensing module; a signal input end of the first control module is connected with a signal output end of the sensing module, a signal output end of the first control module is connected with a signal input end of the second control module, and a signal output end of the second control module is connected with an upper computer; the sensing module comprises a microelectrode array and an interdigital electrode array arranged on a glass substrate, the microelectrode array and the interdigital electrode array are electrically connected with the signal output end, the microelectrode array is used for sensing an electrophysiological signal, the interdigital electrode array is used for sensing an impedance signal, the first control module is used for applying an excitation signal to the sensor and collecting a response signal, and the second control module is used for processing the response signal output by the first control module. The application can realize synchronous acquisition of multiple parameter signals of cells.
Owner:SUN YAT SEN UNIV

Self-adhesive hydrogel photoelectrodes, arrays, devices, applications, and methods of evaluation

This invention discloses a self-adhesive hydrogel photoelectrode, array, device, application, and evaluation method. The self-adhesive hydrogel photoelectrode comprises a self-adhesive hydrogel optical fiber and at least one flexible fiber electrode. The optical fiber has a core-skin structure; the skin is composed of adhesive polymers such as polyvinyl alcohol, polyacrylic acid, and polydopamine, while the core is a transparent hydrogel. The flexible fiber electrode comprises conductive materials such as graphene oxide, carbon nanotubes, and polypyrrole. The flexible fiber electrode is directly integrated onto the surface of the optical fiber through the adhesion of the fiber skin, forming a heterogeneous structural unit integrating optical transmission and electrical conduction. This technology relies on a dynamic interface bonding mechanism to achieve stable and reconfigurable heterogeneous integration in a humid environment. The device simultaneously possesses low optical loss, high conductivity, strong tissue adhesion, and excellent biocompatibility, making it suitable for implantable neural modulation and signal acquisition, in vitro testing, and interface reliability assessment.
Owner:DONGHUA UNIV

Preparation method and system for dimming films based on PET and liquid crystal

This invention relates to the field of thin film preparation, and discloses a method and system for preparing dimming films based on PET and liquid crystal. The method includes: first, acquiring the transmittance parameters of the PET substrate and the phase transition temperature data of the liquid crystal material; constructing an interlayer framework; forming an activated interface layer on the surface of the PET-liquid crystal composite through plasma treatment; coating a liquid crystal dispersion to obtain a pre-cured film; gradient curing based on its thickness distribution data using an ultraviolet light source to form a dimming functional layer; collecting the transmission spectrum curves of the dimming functional layer under different electric field intensities; calculating the duty cycle value of the liquid crystal molecules; configuring a transparent conductive electrode pattern accordingly; and topologically designing it as a uniquely controlled electrode array. Defect clusters are identified and repaired by calculating the electronic control adjustment value; the dimming attenuation parameters of the repaired film are analyzed; and finally, a PET-liquid crystal composite thin film preparation scheme is formulated. This invention can improve the preparation efficiency of dimming films.
Owner:深圳御光新材料有限公司

Elastic wave device with high temperature stability

PCT designated stageWO2026132891A1Impedence networksTransducerElectrode array
The invention relates to an elastic wave device 10000 in the field of elastic wave-based components for areas such as telecommunication. The elastic wave device 1000 of the invention comprises a variable impedance means 1003, 2003, 3003, 10400, a first electromechanical device 3, 11130, in particular, a first transducer 3, 11130, and a second electromechanical device 5, 11140, in particular, a second transducer 5, 11140 or an electrode array configured to reflect at least partially elastic waves emitted by the first electromechanical device 3, an array 4000, 11150 of at least one electrode 1000, 2000, 3000 located between the first electromechanical device 3 and the second electromechanical device 5 in the direction of propagation of the elastic waves, and a temperature determination means 10200 configured to determine a temperature of an operating region of the elastic wave device.
Owner:SOITEC SA

A method for packaging a silicon photonic chip with thermal-induced deformation regulation

PendingCN122449708AThermal isolationPhotonic Chip
The application discloses a kind of thermally induced deformation regulation and control silicon optical chip packaging methods, belong to semiconductor packaging and optoelectronic communication technical field.It includes: obtaining the packaging substrate including flexible compensation area, rigid fixed area and thermal isolation groove;Heating electrode array and double material strain layer are set in flexible compensation area, and temperature sensor is set in rigid fixed area;Silicon optical chip is fixed to the surface of rigid fixed area, and preset bias voltage is input to heating electrode array, so that flexible compensation area generates initial bending deformation state;In the initial bending deformation state, optical fiber assembly is solidified and connected to the end of flexible compensation area, and initial optical coupling link is constructed.The application obtains real-time temperature by temperature sensor, dynamically adjusts driving voltage to change the curvature of flexible compensation area, and drives optical fiber assembly to generate alignment displacement.Active thermal deformation feedback adjustment means is used, which can effectively offset the coupling offset caused by temperature drift and improve the stability of optical coupling link.
Owner:BEIJING YIWEIDA TECHNOLOGY DEVELOPMENT CO LTD

Composite digital acoustic flow control chip, preparation method and multi-dimensional processing method

The application discloses a composite digital acoustic flow control chip, a preparation method and a multi-dimensional processing method. The chip comprises detachably connected upper and lower plates and a gap support assembly arranged between the upper and lower plates. The upper plate comprises a piezoelectric substrate, an acoustic surface wave interdigital electrode array arranged on the piezoelectric substrate, a first dielectric layer covering the interdigital electrode array, a conductive layer arranged on the first dielectric layer, and a first hydrophobic layer arranged on the conductive layer. By constructing the multi-dimensional acoustic wave control unit of the upper plate and the electrode array of the lower plate based on the dielectric wetting effect, the programmable and controllable movement of the droplet sample and the action of the acoustic surface wave in the droplet are realized, the digital control of the acoustic flow control technology is realized, and the capacity of the chip for sample enrichment, control, mixing and fixed-point heating is greatly improved through the design of multiple IDTs.
Owner:XIAMEN UNIV

Ion cyclotron resonance device, control method, and mass spectrometer

ActiveCN116364528BEasy to manufacturelow costElectron/ion optical arrangementsOmegatronsResolution (mass spectrometry)Mass analyzer
The application provides an ion cyclotron resonance device for mass spectrometry, a control method and a mass spectrometer. The device comprises a cylindrical space region for ion introduction, excitation and detection. In the ion excitation process, the ions are excited radially outward from the center of the cylindrical space region. A pair of magnets are arranged axially parallel to the cylindrical space region for generating a magnetic field in the space region. The magnets have opposite polarities. The opposite surfaces of the magnets are perpendicular to the axial direction. The magnetic field intensity of the central region of the space region is greater than that of the outer peripheral region along the radial direction. An electrode array is arranged between the pair of magnets. An alternating voltage is applied to the electrodes of the electrode array for exciting the ions. The ion cyclotron resonance device can solve multiple problems such as device miniaturization, resolution, equipment and manufacturing cost.
Owner:SHIMADZU RES LAB SHANGHAI

Neural microelectrodes with temperature control and temperature measurement functions and their fabrication method

ActiveCN116269410BTo control the temperatureRealize the control functionSensorsDiagnostic recording/measuringTemperature controlMicroelectromechanical systems
This disclosure provides a neural microelectrode with temperature control and temperature measurement functions, which can be applied in the field of microelectromechanical systems (MEMS) biosensor technology. The neural microelectrode includes: a substrate including a detection region; a microelectrode array disposed on the substrate and overlapping with the detection region, the microelectrode array being used to measure the electrical signal of a analyte; a temperature control element disposed on the substrate and overlapping with the detection region, used to control the temperature of the detection region; a temperature measurement element disposed on the substrate and overlapping with the detection region, used to measure the temperature of the detection region; and an insulating layer disposed on the microelectrode array, the temperature control element, and the temperature measurement element, covering the microelectrode array, the temperature control element, and the temperature measurement element. This disclosure integrates temperature control and temperature measurement functions with the neural microelectrode, realizing temperature control and temperature measurement of neurons, while simultaneously recording the electrical signals of neurons.
Owner:UNIV OF SCI & TECH OF CHINA

A Micro-Platform for Rapid Electrolysis and High-Sensitivity Electrochemical Nucleic Acid Detection of Cryptococcus and Its Application

ActiveCN117607222BRapid lysisavoid pollutionMaterial electrochemical variablesElectrolysisElectroporation
This invention belongs to the field of fungal detection technology, specifically relating to a micro-platform for rapid electrolysis and highly sensitive electrochemical nucleic acid detection of Cryptococcus neoformans and its application. The micro-platform includes an integrated microfluidic chip, an external power supply, a sample introduction system, and / or an imaging system. The integrated microfluidic chip includes an electrolysis region, an electrochemical detection region, and an electrode array region. The electrolysis region includes multiple vertically arranged counter electrodes arranged in pairs, and multiple horizontally arranged hollow channels in a serpentine pattern, bonded to the electrode pairs above them. The connection point between every two electroporated channels is the electroporation lysis point. The electrochemical detection region consists of a working electrode, a reference electrode, and a counter electrode. The working electrode is modified with rGO / AuNPs nanomaterials and molecular probes.
Owner:BEIHANG UNIV +1

Crossed strip anode photon counting imaging detector splicing system and splicing method

ActiveCN122237772BSpectral bandsPhotocathode
The present application relates to the technical field of spectral imaging detection, and particularly relates to a cross-bar anode photon counting imaging detector splicing system and a splicing method, which respectively cover ultraviolet, visible and near-infrared bands, each detector unit comprises a vacuum sealed tube composed of a glass window coated with a photocathode, a cylindrical micro-channel plate stack, a resistance anode and a cross-bar anode, and a position reading circuit, wherein the curvature radius of the cylindrical MCP stack is matched with the focal plane curvature radius of the Rowland circle spectrometer to improve the spectral resolution. Four detector units are connected in one-to-one correspondence to form a long strip electrode array in the direction perpendicular to the spectral imaging direction, and the position reading circuit is used for processing charge pulses to determine the electron cloud centroid position. The curvature radius of the cross-bar anode single-photon imaging detector unit can be matched with the curvature radius of the cylindrical focal plane of the Rowland circle spectrometer, the spectral resolution of the spectrometer is improved, and continuous imaging of a wide spectral band of 115 nm to 900 nm is realized.
Owner:CHANGCHUN INST OF OPTICS FINE MECHANICS & PHYSICS CHINESE ACAD OF SCI