113 results about "Treatment effect" patented technology

The present invention comprises: a high-frequency oscillator that transmits high-frequency energy and includes a control unit; a high-frequency connecting line connected to the high-frequency oscillator; and a high-frequency transmission pad connected to the other end of the high-frequency connecting line and attached to the curve of facial skin in close contact with it, wherein the high-frequency transmission pad is configured such that an adhesive pad and a bipolar pad are integrated or separate. This invention relates to a non-invasive automatic facial lifting device using high-frequency energy that adheres closely to the curves of the face to be treated, thereby enabling uniform delivery of high-frequency energy to the skin, allowing for effective treatment without separate operation, minimizing the risk of excessive thermal damage to specific areas of the skin, resolving issues such as pain, scarring, and infection associated with existing invasive technologies, enhancing user convenience and safety through an automated control system and customized settings, and providing uniform treatment effects and reducing treatment time and fatigue by monitoring skin temperature in real time and delivering high-frequency energy according to set output, time, and patterns.

This utility model discloses a gold microneedle treatment head with an internal negative pressure structure, comprising: a shell connected to a main unit at one end; two sets of mounting holes respectively disposed on both sides of the shell; a groove disposed on one side wall of the shell; a needle platform disposed on the inner wall of the groove; and a negative pressure component, which includes through holes and microneedles, with multiple sets of through holes and microneedles. The multiple sets of through holes are equidistantly disposed on the needle platform, and the multiple sets of microneedles are disposed inside the multiple sets of through holes. A negative pressure element is disposed on one side of the multiple sets of through holes and microneedles. By setting a negative pressure component consisting of through holes, microneedles, and a negative pressure element, a negative pressure rod and an adsorption channel can communicate with the through holes. The negative pressure rod and the adsorption channel can draw the through holes to create a negative pressure environment, thereby adsorbing the skin through the through holes. This improves the adsorption efficiency of the microneedle treatment head on the skin and avoids the situation where the needle platform is not conducive to adsorption on the skin, thus improving the treatment effect of the microneedle treatment head.

To provide a method for treating a workpiece, wherein the method comprises the following:introducing at least one workpiece into a treatment chamber;providing a bath of a liquid treatment agent in the treatment chamber;cyclically changing the pressure in the treatment chamber while the treatment agent is in the treatment chamber;in which an enhanced treatment effect is achieved on the workpiece, it is proposed that the method further comprises the following:carrying out at least one pressure change operation in the treatment chamber, during the course of which the pressure in the treatment chamber is decreased at least once and increased at least once while at least one treatment region of at least one workpiece is outside the bath of liquid treatment agent; andcarrying out at least one pressure change operation in the treatment chamber, during the course of which the pressure in the treatment chamber is decreased at least once and increased at least once while the at least one treatment region of the at least one workpiece is within the bath of liquid treatment agent.

The application is suitable for the technical field of medical devices, and provides a bone fracture reduction device, which comprises a linear motion mechanism, a parallel mechanism and a fixing part. The parallel mechanism comprises a first motion assembly, a second motion assembly and a third motion assembly, and the first motion assembly, the second motion assembly and the third motion assembly are all installed on the linear motion mechanism. The fixing part is provided with a first connecting end, a second connecting end and a third connecting end. The first motion assembly is movably connected with the first connecting end, the second motion assembly is movably connected with the second connecting end, the third motion assembly comprises a first end and a second end, the first end is movably connected with the linear motion mechanism, and the second end is movably connected with the third connecting end. Through cooperation between the linear motion mechanism and the first motion assembly, the second motion assembly and the third motion assembly, the fixing part has three rotations, three movements and six degrees of freedom, so that the flexibility of the bone fracture reduction device is higher, and the treatment effect is better.

The utility model relates to the field of anal fistula drainage tube discloses a telescopic anal fistula drainage tube, including the pipe body, the pipe body front inner wall sliding connection has the extension pipe, the pipe body outside passes through and is opened the drainage hole, the pipe body inner wall is provided with the stretching mechanism, the stretching mechanism includes the limiting component and the support component, the limiting component includes the fixed part, the fixed part fixedly connected in the pipe body inner wall, the pipe body inner wall fixedly connected with the limiting bead, the extension pipe outside sets up the limiting slot, and the limiting bead is connected in the limiting slot inside. In the utility model, by pulling the extension pipe makes, the extension pipe is extruded to the limiting bead through the limiting slot, drives the pipe body deformation to remove the limiting of extension pipe, and at the same time, the deformation of the pipe body is limited through the fixed part, is convenient for the limiting of extension pipe, makes the extension pipe can be length adjusted according to the actual condition of patient, improves the applicability of the device, guarantees the treatment effect.

The utility model discloses a kind of human middle hole acupoint patches with double-sided medicine component structure, belong to acupoint patch field, including substrate, the downside of the substrate is provided with medicine release layer, the downside of the medicine release layer is provided with medicine sheet, the upper end of the substrate is provided with first base layer, the upside of the first base layer is glued with covering layer, the upside of the first base layer is provided with first incense piece, the downside of the covering layer is provided with second incense piece;By setting medicine sheet, first incense piece and second incense piece on the upper and lower sides of substrate respectively, so that acupoint patch can be in the meantime in human middle hole, through first incense piece and second incense piece reasonable use the special position of human middle hole, better through human respiration, more fully utilize the comprehensive treatment effect of medicine, aromatic medicine and aromatic essential oil to human body.

The present application relates to the technical field of medicine, and particularly relates to a drug composition with a sequential synergistic repair effect and a preparation method and application thereof. The drug composition comprises liposome I encapsulating caffeic acid and liposome II encapsulating BH4; the liposome I is a ROS-responsive liposome, can specifically respond in a high ROS microenvironment, and then realize on-demand release of caffeic acid; meanwhile, the liposome II protects BH4 from entering cells to play a role, can effectively overcome the defects of difficult dissolution of caffeic acid and easy oxidation of caffeic acid and BH4, can improve the bioavailability of the two drugs, can realize sequential release of caffeic acid and BH4, and can play a synergistic treatment effect on different mechanisms of occurrence of radioactive skin damage, and provides a sequential synergistic repair strategy for clinic. The liposome I and the liposome II are both prepared by a thin film hydration method, and the operation is simple, the conditions are mild, the lipid film is uniformly formed, and the encapsulation rates of caffeic acid and BH4 are high.

This invention discloses an auxiliary method for orthodontic treatment planning based on a digital twin of tooth movement, belonging to the field of orthodontic auxiliary technology. The method includes acquiring cone-beam computed tomography (CBCT) data of the patient's oral cavity and three-dimensional point cloud data of the tooth crown surface to construct a three-dimensional geometric model of the tooth-periodontal ligament-alveolar bone. The three-dimensional geometric model is discretized into a finite element mesh, and based on the patient's age, periodontal biotype, and CT grayscale value, periodontal ligament viscoelastic parameters, alveolar bone grayscale-mechanical mapping parameters, and tooth linear elastic constants are assigned to form an individualized digital twin of tooth movement. A target displacement vector is determined within the individualized digital twin of tooth movement, and the orthodontic force vector and anchorage requirement index are calculated. The anchorage requirement index is used to assist in the design of the orthodontic treatment plan. This invention can effectively improve the accuracy, predictability, and personalization of orthodontic treatment plan design, reduce reliance on experience, and optimize the overall treatment effect.

This utility model relates to an ultrasonic surgical aspiration device, including a main unit, a trolley, a negative pressure system, a handle assembly, a peristaltic pump assembly, a tubing kit, and a wheel assembly. The main unit is placed on the trolley; the handle assembly is connected to the main unit; the peristaltic pump and the negative pressure system are connected to the handle assembly via the tubing kit, which provides cleaning fluid to the handle assembly; the negative pressure system includes a negative pressure vacuum pump, a suction can, and a filter; the negative pressure vacuum pump is located inside the main unit, and the suction can is located on the trolley. The suction port of the negative pressure vacuum pump is connected to the outlet of the suction can through the filter, and the inlet of the suction can is connected to the handle assembly. Its beneficial effects are that the negative pressure system can promptly and thoroughly remove residual contaminants from the handle, effectively preventing handle blockage, improving the treatment effect of surgical instruments on tissues, reducing the risk of surgical interruption, shortening surgical time, alleviating patient pain, and providing a strong guarantee for the stable conduct of the surgery.

The application discloses a construction method and application of an osteoarthritis cartilage organoid, and the method comprises the following steps: 1) mesenchymal stem cells are inoculated on a round bottom culture plate by a Micromass method, and are cultured in a chondrogenic induction culture medium containing dexamethasone, ascorbic acid and TGF-beta 3 for 10-18 days to form a transparent cartilage organoid; and 2) the transparent cartilage organoid is placed in an osteoarthritis induction culture medium containing dexamethasone, L-thyroxine, inflammatory factors (IL-1beta, IL-6 and TNF-alpha) and beta-glycerophosphate sodium for continuous culture for 5-10 days to obtain an osteoarthritis cartilage organoid; the model simultaneously presents multi-dimensional pathological characteristics such as matrix degeneration, hypertrophy, inflammation activation and vascularization trend, and can be used for osteoarthritis pathogenesis research, drug screening and cell treatment effect evaluation; the construction method is controllable and has good repeatability, and provides a reliable three-dimensional in-vitro model for osteoarthritis research.

The application provides a lightweight orthodontic efficacy prediction method and system based on semantics and three-dimensional optimization, relates to the technical field of orthodontic efficacy prediction, and comprises the following steps: obtaining facial images and cephalometric data of historical orthodontic patients before and after orthodontic treatment to form a training set, constructing a structured orthodontic semantic prompt, using the pre-training diffusion model as the basis, using the training set images and the semantic prompt, and fine-tuning the prediction model through the LoRA technology; inputting the orthodontic pre-image and data of a target patient into the image to the prediction model, generating a two-dimensional facial image after orthodontic treatment, and performing three-dimensional reconstruction; optimizing the geometric consistency with the side image, and outputting a three-dimensional model for visual display. Through the combination of the LoRA fine-tuning technology, the structured medical semantic prompt and the three-dimensional geometric consistency optimization, the application can train an efficient prediction model under a small amount of paired data, reduce the calculation cost of model training and reasoning, adapt to the deployment of a clinical environment, and realize the controllability and interpretability of the generated results through the medical semantic prompt.

This application proposes a hotel inventory management method based on causal effect estimation, comprising: in response to a sell-out event of a target room type, acquiring a dataset related to the target room type; learning a multidimensional feature representation corresponding to the target room type from the dataset; estimating the target individual treatment effect corresponding to the target room type based on the multidimensional feature representation; the target individual treatment effect is the sum of the first individual treatment effect corresponding to the target room type and the second individual treatment effect corresponding to similar room types in the same region as the target room type; the first individual treatment effect represents the causal effect of the increase in inventory for the target room type resulting in successful booking of the increased inventory; the second individual treatment effect represents the causal effect of the increase in inventory for the target room type resulting in successful booking of similar room types; and executing the process of increasing inventory for the target room type if the estimated target individual treatment effect is not less than zero.

The present application relates to the technical fields of biomedical engineering, and provides a kind of orthopedic force dynamic monitoring analysis method, scoliosis brace and brace system, comprising: brace main body, speed reducer and monitoring unit;First, obtain temperature monitoring data and pressure monitoring data;Then according to temperature monitoring data and pressure monitoring data, determine current correction state;Finally, according to the current correction state and the pressure monitoring data, determine the driving instruction, to indicate the speed reducer adjusts the correction parameter of the brace main body.The present application determines the correction effectiveness by temperature and pressure double sensing combination, significantly improves the monitoring accuracy of wearing compliance, realizes real-time optimization and abnormal state automatic correction of orthopedic force, and greatly improves the correction stability and treatment effect.

A medical image diagnostic apparatus, an inference method, an inference apparatus, and a storage medium according to an embodiment include acquiring attribute information for a target patient to be subjected to inference, and estimating a causal relationship between the attribute information for the target patient and a treatment effect for the target patient using a causal inference model including a decision tree model optimized based on knowledge information defining rules for determining a treatment to be applied to other patient and clinical information indicating relationship between attribute information for the other patient and other treatment effect observed after the treatment.

The application belongs to the technical field of surface treatment equipment, and discloses an automatic polishing and deburring integrated device, which comprises a treatment seat, the top surface and the bottom surface of the treatment seat are respectively provided with a guide groove and a bottom cavity, the inner part of the treatment seat is respectively provided with an assembly cavity and an adaptive ring cavity, and the top surface of the treatment seat is fixedly provided with a lifting arm. The second electric push rod in the deburring assembly reduces the pressure on the outer side of the metal round plate, and cooperates with the rotation of the deburring assembly, so that the connecting block changes from static compression to dynamic grinding, thereby realizing the deburring treatment of the outer side arc surface of the metal round plate. The whole polishing and deburring are continuously completed, the switching speed is fast, and the efficiency is high. During the polishing of the top surface of the metal round plate and the deburring of the outer side arc surface, the polishing assembly and the deburring assembly respectively undertake the positioning task of different treatment processes, maintain the stability of automatic polishing and deburring, have good comprehensive treatment effect, and have high efficiency.

This invention relates to the field of orthodontics, and discloses a method, device, and storage medium for designing a combined orthognathic and orthodontic treatment plan. The method involves obtaining an initial head model of the user; the position of the jawbone in the initial head model is the initial position of the jawbone; obtaining the target position of the user's jawbone; based on the initial head model, calculating several intermediate positions of the jawbone from the initial position to the target position, arranging teeth at each jawbone position, and obtaining a head model corresponding to each jawbone position after tooth arrangement; the jawbone position is either the intermediate position or the target position; selecting a head model that meets preset conditions from the head models corresponding to each jawbone position; and designing a treatment plan based on the head model that meets the preset conditions. This invention combines the orthognathic treatment effect at different stages with the orthodontic effect to obtain a comprehensive treatment effect, reducing communication time between orthodontists and orthognathic surgeons, and quickly providing a treatment plan that meets the needs of combined treatment.

The application discloses a harmonic distributed treatment method based on a self-learning algorithm, and belongs to the field of harmonic treatment of distribution networks. The method adopts a voltage detection active power filter (VDAPF) to treat harmonics, and the key to distributed treatment of a "double-high" distribution network is proposed. The application proposes a method for quantifying the global treatment effect and the degree of participation of VDAPF in collaborative treatment, respectively, to obtain a preliminary performance factor. The preliminary performance factor is converted into a final performance factor based on a self-learning algorithm, and the local control G-U lifting adjustment characteristics of the VDAPF are combined to realize self-organizing distributed optimization of treatment equipment in a distributed treatment system. The harmonic distributed treatment method based on the self-learning algorithm can solve the problem that scattered treatment is not applicable due to the intensification and decentralization of harmonic sources, and can change passive harmonic treatment into active harmonic treatment.

The utility model provides a kind of thoracolumbar orthotic instrument, it is related to the technical field of correction equipment.Thoracolumbar orthotic instrument includes fixed part, locking part and rope body.The number of fixed part and locking part is same and all is multiple, multiple locking parts are connected with multiple fixed parts one to one.Correspondingly, multiple fixed parts are all provided with rope part in one side wall, and the other side wall is provided with fixed part, and fixed part is used to be fixed in vertebral body;Locking part is also used to be fixed in vertebral body;Rope body is sequentially wound in the rope part of multiple fixed parts;Therefore, the stability of fixed part can be effectively enhanced by locking part and fixed part, to avoid displacement or rotation problem;And by rope body sequentially winding in the rope part of each fixed part, form continuous, uniform stress correction force system, improve correction stability, and can be according to patient individual situation and adolescent growth potential carry out scoliosis non-fusion dynamic adjustment;Thus, stable and effective correction support is provided for patient, and treatment effect and life quality are improved.

The present application belongs to the technical field of Dioscorea alata Blume anthracnose prevention and treatment, and particularly relates to application of a biological agent material for enhancing expression of DaMYB48 in resisting anthracnose. The application of the biological agent material for enhancing expression of DaMYB48 in resisting anthracnose is characterized in that the nucleotide sequence of DaMYB48 is shown as SEQ ID NO. 3. The expression of DaMYB48 is enhanced to enhance the resistance of the plant to anthracnose. The application of the agent for enhancing expression of DaMYB48 in resisting anthracnose of Dioscorea alata Blume can significantly enhance the resistance of the plant to anthracnose, and the area of the disease spot is significantly reduced, and the prevention and treatment effect is stable. The material used in the present application is a biological material, and will not pollute the environment. On the other hand, the present application reduces the invasion of anthracnose by regulating the closure of stomata of leaves, belongs to physical action, and thus will not cause the anthracnose pathogen to produce drug resistance.

The invention provides a living single cell multi-modal in-situ detection analysis method and a treatment scheme evaluation optimization method, and relates to the technical field of precision medical treatment, and the method comprises the following steps: obtaining multi-modal data of a living single cell to be detected in situ; the multi-modal data comprises at least two of the following data: electrical impedance data of a living single cell to be detected under a plurality of frequencies, Raman spectrum data of the living single cell to be detected, and image data of the living single cell to be detected; the frequency is the frequency of an alternating current signal applied to the cell through the electrode; extracting multi-modal dynamic characteristics of the living single cell to be detected from the multi-modal data by adopting a combined modal data analysis method; wherein the combined modal data analysis method comprises a cell electrophysiological analysis method, a cell multi-molecular spectroscopy analysis method and a cell image analysis method. Therefore, the multi-modal dynamic measurement method is utilized to obtain multiple groups of dynamic characteristic information of the cells, and accurate treatment effect evaluation and process optimization can be realized.

The application discloses an anti-MPO human IgG monoclonal antibody and application thereof. Amino acid sequences of CDR1, CDR2 and CDR3 in a heavy chain variable region of the anti-MPO human IgG monoclonal antibody are sequentially shown as SEQ ID No. 1 26-33, 51-58 and 97-111, and amino acid sequences of CDR1, CDR2 and CDR3 in a light chain variable region are sequentially shown as SEQ ID No. 2 26-34, 52-54 and 91-102. Experiments prove that the monoclonal antibody not only has good binding activity with MPO, with a Kd of 0.0088 nM and an EC50 of 1.33 ng / mL, but also has good universality and stability, and can be used as MPO-ANCA quality control instead of a clinical positive sample, and then used for AAV diagnosis, activity evaluation and treatment effect monitoring.

The application provides a kind of proton therapy system and its use method, the proton therapy system includes: treatment planning module, for generating irradiation data according to input treatment planning data;Beam control module, for generating the control parameter of accelerator module according to irradiation data and preset compensation data;Accelerator module, for generating proton beam current in response to control parameter;Measurement module, for measuring the actual current parameter of proton beam current;Treatment head, set in the path of proton beam current to target treatment location, to control the on-off of proton beam current path;Wherein, beam control module is also used to compare actual current parameter with target current parameter in irradiation data, and update compensation data based on comparison result, until the actual current parameter of proton beam current and target current parameter are the same according to updated compensation data.The application can enhance the treatment effect by determining the accuracy of dosimetric parameters through pre-checking process.

The application relates to the technical field of neuromodulation devices, and provides a bone conduction neuromodulation device and a control method. The bone conduction neuromodulation device comprises an electroencephalogram acquisition device, a bone conduction vibration device and a control device. The control device is configured to extract electroencephalogram features in an electroencephalogram signal, determine vibration control parameters according to the electroencephalogram features, control the bone conduction vibration device to generate vibration according to the vibration control parameters, and adaptively adjust the vibration control parameters based on changes in the extracted electroencephalogram features during the process of generating vibration by the bone conduction vibration device, so as to form a closed-loop control. The closed-loop control mechanism based on real-time electroencephalogram feedback makes the vibration stimulation always adapt to the instant neural state of a target user, helps to reduce the influence of individual differences on the treatment effect, improves the stability and repeatability of the treatment effect, and further enhances the overall reliability of the bone conduction neuromodulation in clinical application.

This treatment optimization system comprises: a data collection unit that collects biological data of a treatment-target person; a data analysis unit that (1) causes an AI, which has been trained by machine learning, to analyze the biological data obtained before treatment and to create a detailed treatment plan suitable for the treatment-target person, (2) causes the AI to analyze biological data of the treatment-target person obtained during the treatment, to estimate, as an evaluation index of the treatment-target person with respect to the treatment, at least one of pain, numbness, a feeling of oppression, the presence or absence of a feeling of weakness, the presence or absence of a feeling of discomfort, a change in the feeling of discomfort, relief of the feeling of discomfort, and a feeling of comfort, and to create a detailed treatment plan corrected according to the estimated evaluation index of the treatment-target person, and (3) causes the AI to analyze biological data of the treatment-target person obtained after the treatment, to estimate the effect of the treatment, and to incorporate the obtained result in creating the next detailed treatment plan for the treatment-target person; and a display unit that presents, to a practitioner, the detailed treatment plan created by the AI.

The application provides a high-efficiency hemostatic dressing, a preparation method and application thereof. The hemostatic dressing is a crosslinked product containing hydroxypropyl chitosan and low molecular weight eucommia ulmoides gum. The hemostatic dressing has a high swelling rate, can better absorb water-soluble exudates, and is beneficial to rapid hemostasis. The hemostatic dressing has better mechanical strength, which indicates that the hemostatic dressing has excellent compression resistance and high-load impact resistance, so that appropriate eucommia ulmoides gum-based dressing can be selected according to specific application scenes and wound characteristics, so as to improve the treatment effect.

The application relates to the field of mirabilite swelling reduction, and specifically discloses a novel mirabilite swelling reduction device, which comprises a protector, a bandage for fixing the protector on a patient, and an air bag arranged on the protector. The protector is provided with a cavity for loading mirabilite on the side close to the patient. A limiting piece is arranged on the inner wall of the cavity to limit the mirabilite. The limiting piece is provided with an embedding part capable of being partially embedded in the mirabilite. The novel mirabilite swelling reduction device can prevent the mispositioning of the mirabilite from affecting the treatment effect during treatment.