330 results about "Deep tissue" patented technology

The present invention relates to a novel microneedle platform for minimally invasive delivery of therapeutic agents and the modulation of the neuro-immune axis in deep tissue. The present invention also adopts an innovative approach for minimally invasive and precisely controllable treatment of deep cutaneous diseases, conditions, and disorders using said electroconductive MN patch, which has the potential to benefit millions of patients worldwide.

The invention relates to the technical field of optical coherence elastography, in particular to a microscopic optical coherence elastography method and system.The method comprises the steps that a collection trigger signal is generated, a vibration control signal and a position control signal are output at the same time, and a target excitation system corresponding to a to-be-detected sample is determined; triggering the line scanning camera by collecting a trigger signal, collecting a line scanning image of the to-be-tested sample, and adjusting the position of the to-be-tested sample in the sample table so as to place the to-be-tested sample at a target test position; controlling a bending actuator or an ultrasonic transducer to vibrate by using the vibration control signal so as to excite low-frequency shear waves or ultrasonic waves in the sample to be detected; the to-be-detected sample is scanned through the position control signal to obtain propagation information of low-frequency shear waves or ultrasonic waves, and the pixel-level biomechanical properties of the to-be-detected sample are reconstructed by using a near-field full-wave inversion algorithm, so that the microstructure of a deeper tissue can be observed, the imaging speed is relatively high, and the detection performance of small inclusions is improved.

The pair of expandable foreign body forceps comprises an outer sleeve and a foreign body forceps body, a limiting assembly is arranged at one end of the outer sleeve, and an expansion assembly is arranged at one end of the outer sleeve; the expansion assembly comprises a first notch formed in one end of the outer sleeve, an expansion air pipe is arranged in the first notch, one end of the expansion air pipe is fixedly connected with an expansion air bag, one end of the expansion air pipe is fixedly connected with a three-way pipe, one end of the three-way pipe is fixedly connected with an injector, and one end of the three-way pipe is provided with an expansion valve. A rotating plate is rotationally installed on the outer surface of the cylinder, an arc-shaped plate is fixedly installed on one side of the rotating plate, and an anti-skid pad is fixedly installed on the inner surface of the arc-shaped plate. According to the pair of expandable foreign body forceps, foreign bodies can be blocked while an esophageal cavity is expanded through the arranged expansion assembly, so that the situation that the foreign bodies are pushed to deeper tissues is prevented, and the efficiency of taking out the foreign bodies by the pair of expandable foreign body forceps is improved.

The invention discloses a near-infrared two-region activatable probe as well as a preparation method and application thereof. The near-infrared second-region activatable probe comprises a near-infrared second-region fluorescent light-emitting unit and an analyte specific response unit; the near-infrared second-region light-emitting unit comprises a hemicyanine fluorophore structure; when the analyte specific response unit is chemically coupled with the near-infrared second-region light-emitting unit, the intramolecular charge transfer process of the light-emitting unit can be inhibited, and fluorescence quenching is caused; the analyte specific response unit is separated from the light-emitting unit after being subjected to specific reaction with an analyte, so that fluorescence is activated. The near-infrared two-region hemicyanine fluorophore selected by the near-infrared two-region activatable probe has higher fluorescence quantum efficiency, and the near-infrared two-region probe which can be activated by a specific analyte and has a high on-off ratio can be constructed by introducing an analyte specific response unit, so that high-temporal-spatial-resolution fluorescence detection of deep tissues can be realized; the method has a wide application prospect in the field of biomedical detection.

The invention relates to a regenerated decellularized adipose derivative as well as a preparation method and application thereof. The preparation raw material of the regenerated decellularized adipose derivative is prepared from a vascular matrix component (SVF) separated from human adipose tissue through decellularization treatment and freeze drying; the prepared regenerated decellularized adipose derivative is a porous material, the porosity is greater than 90%, and the aperture is 50-200 [mu] m; the composition comprises the following components in percentage by weight: 60-70% of collagen, 15-20% of elastin, 1 * 10 < 10 >-5 * 10 < 10 > particles / g of exosome, less than or equal to 5 ng / mg of DNA (deoxyribonucleic acid) residue, more than or equal to 30 ng / g of VEGF (vascular endothelial growth factor) and more than or equal to 15 ng / g of FGF-2 (fibroblast growth factor). The prepared regenerated decellularized adipose derivative is low in DNA residual quantity, rich in growth factors and capable of meeting the requirement for deep tissue filling due to the fact that the collagen content and the elastin content are high.

The present invention introduces a medical stapler configured for efficient wound and incision closure with cosmetically appealing end result, Utilizing a four-legged staple and a single-track dispensing mechanism. The medical stapler enables rapid deployment of staples in a vertical mattress suture fashion, facilitating optimal tissue approximation without the requirement of suturing. The deployment mechanism is designed to affect a staggered release of the fine legs and the standard legs of each staple, thereby promoting engagement with superficial tissue layers and engagement with deeper tissue layers. Additionally, the staple assembly allows for independent deployment of the fine legs from the standard legs as needed, enhancing procedural efficiency and flexibility.

The invention provides a surgical process management method and system, and relates to the technical field of surgical process management.The method comprises the steps that DTI, fMRI and 3D-T1WI image data are fused through a non-rigid registration algorithm, a three-dimensional brain network atlas is generated, then an LSTM deep learning model is constructed, a brain surface displacement field monitored in real time in an operation is used as input, and an LSTM deep learning model is constructed; a deep tissue displacement value is used as a label for training to obtain a deep tissue displacement predicted value, and a dynamic relation between brain neural element electrical activity and oxyhemoglobin saturation is analyzed by combining data monitored by high-frequency EEG and near infrared spectrum and utilizing a wavelet time-frequency coherence algorithm to obtain a dynamic influence coefficient; and finally, combining the deep tissue displacement predicted value with the dynamic influence coefficient, calculating a comprehensive evaluation index, and comparing the comprehensive evaluation index with a preset threshold value, so that a surgeon can quickly adjust an operation strategy and timely deal with possible risks.

Various example of the present disclosure provide sensing apparatuses configured for wearable and wireless use for deep tissue physiological monitoring. The sensing apparatuses may be embodied by a thin flexible patch configured to conform with a skin surface of a subject. A sensing apparatus may include a plurality of microneedles oriented to extend towards and penetrate into the subject to a shallow depth. The microneedles may be configured as waveguides for a given sensing modality (e.g., light, ultrasound), such that sensing wave signals propagate to deep tissues. For the sensing, the sensing apparatus includes waveform generators (e.g., light-emitted diodes) and waveform detectors (e.g., photodiodes). Machine learning models may be used to process and denoise sampled data from the waveform detectors and to generate accurate and reliable physiological measurements, including heart rate, respiratory rate, pulse intensity, respiratory intensity, blood oximetry, tissue oximetry, blood flow rate, and / or the like.

The invention discloses a cold therapy method based on dynamic temperature feedback and intelligent adjustment, and the method comprises the steps: loading a cold therapy preset scheme from a database of a system, and carrying out the self-inspection of equipment of a sensing layer; collecting temperature distribution information of the skin surface of the treated part of the patient to obtain thermal imaging data; acquiring blood perfusion rate information; acquiring tissue moisture content and impedance phase angle information; establishing a temperature mapping relation from the skin surface to the deep tissue; the surface boundary condition is set as the skin surface temperature actually measured by the infrared array, and the deep boundary condition is set as an adiabatic hypothesis; and fusing the acquired multi-source observation data with the numerical solution result. The system has the advantages that accurate control over the cold therapy temperature is achieved, the protection response time is optimized, the safety of a patient in the cold therapy process is guaranteed, the treatment effect is improved, a doctor can conveniently make a personalized treatment scheme, efficient information interaction between the doctor and the patient is achieved, and the treatment experience of the patient is improved.

The invention discloses a topological mapping monitoring and correcting method for abnormal scapular brachial rhythm after breast surgery, and belongs to the field of medical rehabilitation and computer vision. The method comprises the following steps: acquiring a trunk dynamic three-dimensional point cloud and infrared thermal imaging data; constructing a multi-layer collaborative dynamic topology network fusing a skeleton structure, soft tissue deformation and physiological activeness; extracting an intrinsic motion field and comparing the intrinsic motion field with the ideal model to generate deviation measurement; and calculating a dynamic instability index, comparing the dynamic instability index with a threshold value, and triggering optimization energy correction path calculation and instruction output. According to the method, the multi-dimensional topological mapping and dynamics prediction technology is adopted, accurate recognition and feed-forward early warning of motion abnormity under the influence of deep tissue adhesion after the breast surgery can be achieved, rehabilitation of a patient is guided through an energy consumption minimization path, and the accuracy of shoulder joint function remodeling and the individualized treatment effect are improved.

The invention discloses a preparation method of collagen nano polymer particles, which comprises the following steps: carrying out surface hydrolysis on organized collagen to prepare a microsphere base material; the preparation method comprises the following steps: uniformly mixing a microsphere base material, a target load, a nonionic surfactant and polyol ester in proportion to prepare a microsphere modified base material; and uniformly mixing the microsphere modified base material, an ether compound and a chemical auxiliary agent according to a ratio to prepare collagen microspheres, namely the collagen nano polymer particles. The preparation method comprises the following steps: firstly, reducing the volume of collagen through enzyme hydrolysis, reducing biological stimulation possibly caused by drug loading, and strengthening the drug loading property of the collagen nano polymer; and secondly, a polymer crystal region appears in the carrier protein in an aqueous solution by utilizing subsequent surface modification, so that the drug carrier can control the release progress of the loaded drug, and the drug carrier can permeate into deep tissues through the surface layer of the skin.

The invention, which belongs to the technical field of medical image processing and computer vision, discloses a multispectral imaging-assisted post-radiotherapy skin injury early detection system comprising a multispectral data acquisition module, a deep tissue feature extraction module, a three-dimensional lesion segmentation module and a space-time tracking evaluation module. The subcutaneous 2.5 cm depth tissue information is obtained through multispectral imaging at the wave band of 400-1350nm, blood perfusion, melanin concentration, collagen structure and other physiological parameters are inversed based on the radiation transfer theory, a three-dimensional medical image segmentation algorithm is adopted to achieve three-dimensional accurate segmentation of an injury area, a spatio-temporal evolution model is established to predict the injury development trend, and the damage development trend is predicted. The radioactive skin injury can be detected in the subclinical period, the detection time window is advanced by 5.2 days on average, the occurrence rate of severe dermatitis is reduced by 65%, and a basis is provided for clinical timely intervention.

The invention discloses a red fluorescent silicon nanodot as well as a preparation method and application thereof. The method comprises the following steps: S1, weighing sulforhodamine 101, adding ultrapure water for dissolving, then adding N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, uniformly stirring, transferring the obtained mixture into a reaction kettle, and heating for reaction; and S2, after the reaction is finished, cooling to room temperature, purifying the obtained product by using a silica gel chromatographic column, eluting by using an eluent, collecting the eluent, and finally, freeze-drying to obtain the red fluorescent silicon nanodots. Compared with common blue-green fluorescence, red fluorescence emission has deeper tissue penetrability and background fluorescence interference resistance; the silicon nanodot provided by the invention not only has excellent light stability and high quantum yield, but also has characteristics similar to lipophilic cations, and can specifically target mitochondria in living cells; in addition, the silicon nanodots also show excellent imaging ability in zebrafish embryos and juvenile fish bodies.

The invention discloses a near-infrared confocal microscopic imaging system and a near-infrared confocal microscopic imaging method, and relates to the technical field of optical microscopic imaging. The method comprises the following steps that near-infrared exciting light sequentially passes through a beam expanding system, a liquid lens and a confocal scanning light path to irradiate a to-be-detected sample so as to generate a near-infrared fluorescence signal, and the liquid lens is used for adaptively adjusting the focal length and wavefront morphology according to the depth of the to-be-detected sample; a photomultiplier detects the near-infrared fluorescence signal after non-focus scattered light is filtered out through the confocal scanning light path and the pinhole, and a fluorescence signal image is obtained; and according to the fluorescence signal image, carrying out iterative optimization on the focal length and phase modulation parameters of the liquid lens to maximize the image sharpness or the signal-to-noise ratio and realize the three-dimensional microscopic imaging of the deep tissue. According to the near-infrared confocal microscopic imaging method provided by the invention, deep near-infrared microscopic imaging with low phototoxicity, low cost and high resolution can be realized.

The invention discloses a preparation method of a health-care medicinal patch capable of dispelling wind and eliminating dampness. According to the invention, a multi-dimensional synergistic effect is realized through organic fusion of a traditional Chinese medicine theory and a modern preparation technology. The monarch drug notopterygium root and radix clematidis play the main effects of dispelling wind and eliminating dampness, and the monarch drug notopterygium root and radix clematidis are matched with a collateral dredging network formed by radix angelicae pubescentis and ligusticum wallichii, so that joint cold-dampness retardation can be deeply relieved; local microcirculation can be activated by the meridian warming characteristic of the cassia twig and the folium artemisiae argyi, and penetration of the medicine effect to deep tissues is enhanced by the bidirectional penetration effect of the lycopodium clavatum and the garden balsam stem. The innovatively introduced capsaicin and clove oil form alternate cold and hot stimulation, so that angiotelectasis is promoted, drug absorption is accelerated, hot burning discomfort of a traditional plaster is relieved through the cooling effect, balanced improvement of treatment comfort is achieved, gradient release of drug components is achieved through the three technologies of nano-powder drug loading, microcapsule controlled release and gel slow release, and the curative effect is improved. And the treatment effect is improved.

Disclosed herein is a method for treating skin wounds in a patient in need of such treatment, comprising applying a foamed composition comprising nitric oxide to the area of skin requiring such treatment. The wound may be selected from the group consisting of skin ulcers, including diabetic foot ulcers (DFUs), venous leg ulcers (VLUs), arterial ulcers, decubitus (pressure) ulcers or other pressure injuries, deep tissue injuries (DTIs), burns, abrasions, skin tears, or bruises.

The utility model discloses a skin beautifying device, and relates to the technical field of beautifying instruments, and the skin beautifying device comprises a controller, an ultrasonic transmitter and a radio frequency transmitter; the controller controls the ultrasonic transmitter and the radio frequency transmitter to work at the same time according to the control signal generated by the operation of the user, so that the ultrasonic transmitter sends ultrasonic energy to the deep skin tissue of an area designated by the user when receiving the control signal, and the deep beautifying effect is achieved; meanwhile, when the radio frequency transmitter receives the control signal, radio frequency energy is transmitted to skin superficial layer tissue of another user designated area, so that the superficial layer beautifying effect is achieved. According to the technical scheme, two beautifying modes can be carried out on the skin area designated by the user in a time-space superposition mode by sliding on the skin, the overall effect is better, meanwhile, radio frequency energy can be fed back to the user in a heat mode, the user is more comfortable in the using process, and the sensory experience of the user is improved.

The utility model discloses a physiotherapy massage head and a fascia gun, and relates to the technical field of massage equipment, the physiotherapy massage head comprises a shell, a light physiotherapy assembly and an ultrasonic massage assembly, the shell is provided with an accommodating cavity; the light physiotherapy assembly is arranged in the containing cavity, the light physiotherapy assembly is annularly arranged, and a mounting hole is formed in the light physiotherapy assembly; the ultrasonic massage assembly is arranged in the mounting hole, and at least part of the ultrasonic massage assembly is exposed out of the mounting hole; wherein the ultrasonic massage assembly is used for massaging a user, and the optical physiotherapy assembly is used for emitting physiotherapy light to the user; according to the technical scheme provided by the utility model, a user can simultaneously obtain massage and physiotherapy effects on local deep tissues which are massaged by the physiotherapy massage head.

The invention belongs to the technical field of surgical instruments, and particularly relates to an incision retraction dilator for small incision deep tissue, which comprises a fixing mechanism, a fixing mechanism, a fixing mechanism and a traction mechanism, the expansion ring is arranged on the inner wall of the mounting block; the retraction mechanism is arranged at the top of the mounting block; the blood cleaning mechanism is mounted on the outer wall of the expansion ring, and the extension rod is arranged on the opposite side of the expansion ring; according to the retractor, the retractor mechanism is arranged, the end of the expansion assembly makes contact with an incision of a patient, the width of the expansion assembly is determined according to the size of the incision of the patient, the retractor is suitable for various different types of operations, the size of the position making contact with the incision is flexibly controlled according to the length of the incision, and the operation is more convenient. Compared with manual operation, expansion can be maintained more conveniently and stably through a mechanical means, and the requirement for the number of medical workers is reduced.

The invention relates to the technical field of physiotherapy equipment, and discloses physiotherapy equipment and a physiotherapy method based on far-infrared light wave superposition, and the equipment comprises a far-infrared mechanism which comprises a far-infrared heating blanket and a protective fabric sewn on the outer surface of the far-infrared heating blanket, the double-layer graphene cloth infrared ray generating layer is arranged in an inner cavity of the far infrared heating blanket; the vertical bearing mechanism comprises a movable base located on the outer side of the far infrared heating blanket, a box body fixedly installed on one side of the top of the movable base and a physiotherapy radiation assembly arranged on the other side of the top of the movable base; and the auxiliary positioning mechanism is matched with the far infrared mechanism for use. Through the superposition and diffraction technology of far infrared light waves, the distribution and intensity of the light waves are optimized, the penetrating power and treatment effect on deep tissues of the human body are improved, accurate conditioning and treatment on the human body are achieved, and the device is reasonable in structure, easy and convenient to operate, safe, comfortable and wide in application prospect.

The application discloses a kind of pre-targeting probe combination for in vivo unstable iron pool imaging and its preparation method and application, and the pre-targeting probe combination includes Fe 2+ Responsive paramagnetic probe GdEpTz and fluorescent signal reporter probe 2E-Tco-Hcy, Fe 2+ Responsive paramagnetic probe GdEpTz and Fe 2+ And after interaction with endogenous protein, by generating free radicals and covalent crosslinking, induce longitudinal relaxation rate (r1) significantly increase about 104.1%, while realizing the efficient enrichment of tetrazine group Tz in lesion part, and the enriched Tz is captured by efficient IEDDA bioorthogonal reaction fluorescent signal reporter probe 2E-Tco-Hcy, trigger fluorescent signal to produce 155.5-fold significant enhancement.The application introduces the bioorthogonal pre-targeting strategy based on reverse electron Diels-Alder (IEDDA) reaction, aims to realize the high selectivity, high contrast synchronous visualization monitoring of dynamic change in deep tissue Fe 2+ Target-induced activation" and "bioorthogonal chemistry".

The application discloses a deep intracranial tissue suturing and ligature instrument, which can realize suturing and ligature of deep human tissues (especially intracranial surgery). The instrument can realize suturing and ligature of deep tissues in minimally invasive treatment in clinical surgery, and can solve the problems of small operation space, difficult suturing and easy damage to surrounding tissues in traditional surgery. The operation includes two parts of suturing and steering, and the suturing operation is completed by two interchangeable needle holding levers. A universal joint device held by the rear lever can be adjusted in direction according to different requirements, and is used for coping with various complex situations.

The application discloses a kind of magnetically responsive hydrogel optical fiber and its preparation and application, belong to medical biomaterial field.The optical fiber includes from inside to outside: polyethylene glycol diacrylate and acrylamide photocrosslinking light transmission core layer;Calcium alginate low refractive index skin layer;Doped nano-magnetic response layer of ferriferrous oxide;And polydopamine grafting polyvinylpyrrolidone lubricating layer.It is prepared by coaxial extrusion and light / calcium step-by-step crosslinking.The structure realizes the spatial isolation and anti-interference of light transmission and magnetic drive, has low background light loss and anti-bending stability, has biomechanics matching, ultra-low friction and magnetic field accurate active navigation ability, solves the pain point that extremely soft optical fiber is difficult to directional intervention.Suitable for deep tissue precise photothermal therapy, in vivo continuous optical sensing and minimally invasive diagnosis and treatment integration and other frontier medical fields.

The invention discloses a formula of a Chinese herbal medicine patch for activating blood and dredging meridians and collaterals. According to the invention, a distinct-level efficacy system is formed through a monarch, minister, assistant and guide compatibility theory of traditional Chinese medicines and a modern preparation technology. The monarch drug group is used for promoting blood circulation to remove blood stasis as a core and is matched with the channel-clearing and collateral-activating components of the ministerial drug group, so that local qi-blood circulation can be effectively promoted, and the meridian blocking state is improved. The traditional transdermal limitation is broken through by an intelligent permeation enhancing technology adopted by the adjuvant drug group, so that the drug components rapidly permeate into deep tissues and are continuously released, the advantage of overall regulation of traditional Chinese medicines is reserved, and the problem of low bioavailability of an external preparation is solved. The precise design of each component in spatial distribution and time release realizes quick-acting and long-acting dynamic balance, is particularly suitable for the requirements of different pathological stages such as chronic strain or acute sprain, forms multi-target intervention in the aspects of improving microcirculation, relieving pain, eliminating swelling and the like, and has a wide application prospect. And compared with the traditional plaster, the plaster better meets the requirement of modern clinic on precise treatment.

The present application relates to the technical field of lesion recognition, in particular to an automatic lesion recognition ultrasonic system for real-time monitoring, which comprises a delay path discrimination module, a gray level trend detection module, a texture feature screening module, a feature fusion sorting module and a region highlight labeling module. Based on continuous ultrasonic frames, the collected deep tissue echo path is analyzed, and the echo arrival time of each pixel point in the continuous frame is detected. The present application supports multi-type data fusion judgment through a comprehensive judgment process supported by multi-dimensional parameter collaborative screening, penetration behavior, gray level trend and texture aggregation. The regional abnormal priority sorting mode improves the hierarchy of lesion feature discrimination, provides partition directional recognition for local structural abnormalities and early micro-variation, and converts the feature judgment result into a high confidence region label by a weight aggregation method. The image output process automatically completes the real-time visual presentation of the high-risk area, improving the clarity and pertinence of the lesion region presentation.

This invention discloses a naphthimide-based fluorescent probe for detecting HClO and its preparation method. The fluorescent molecular probe uses naphthimide as the fluorophore and C=N as the specific reaction site for HClO. Due to the presence of the naphthimide fluorophore, the probe molecule exhibits two-photon properties, enabling deep tissue penetration, reducing background noise, and facilitating fluorescence imaging of biological systems. Furthermore, the introduced morpholine group allows for lysosomal targeting, enabling the monitoring of hypochlorous acid concentration levels in lysosomes, making it a valuable tool for early disease diagnosis. In addition, this type of probe molecule is simple to synthesize, operates under mild reaction conditions, exhibits stable optical properties, and has a high synthesis yield. It can detect a wide range of HClO, making it practically valuable in fields such as biochemistry and environmental science.

The utility model discloses a spectrum therapeutic apparatus for female reproductive health, which belongs to the technical field of medical instruments and comprises a main shell, a tubular frame, an omnibearing irradiation lamp group and a control component, the tubular frame is fixedly arranged in the main shell, a polygonal mounting part is arranged at the front end of the tubular frame, and the omnibearing irradiation lamp group is arranged in the main shell. The polygonal installation part is fixedly connected with an all-directional irradiation lamp set, the tubular frame is provided with a control assembly, and the control assembly is electrically connected with the all-directional irradiation lamp set to release red light for treatment. According to the utility model, the polygonal mounting part is designed for fixing the plurality of strip-shaped lamp panels, and the front lamp panel is designed at the front ends of the plurality of strip-shaped lamp panels, so that 360-degree annular irradiation and front end part irradiation are formed, red light non-contact treatment is carried out on side wall tissues and depth part tissues of a vagina, all-dimensional uniform irradiation treatment is realized, and the treatment efficiency is improved. The clinical requirements are further met; the treatment effect is improved.

The present invention is directed to a monitoring apparatus and method for preventing pressure injuries. More specifically, an apparatus and method that is portable, multi-functional, and easy to use, capable of passive monitoring, AI triage monitoring, and EMR integration that can detect deep tissue injuries, falls, and / or bed wetness, using an equitable approach to detection.

1. Name of the Design Product: Knot Pusher. 2. Use of the Design Product: For tying knots in deep tissues during minimally invasive surgery. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: Front View.

The invention discloses a pressure monitoring device and method for evaluating pressure sore risk, and relates to the technical field of medical equipment. The system comprises a pressure sensing unit used for collecting pressure distribution data between the body surface of a patient and a supporting surface; the distance measuring device is used for measuring the distance between the device and the body surface of the patient. According to the method, information of three different dimensions of pressure distribution, body surface image and deep thermal imaging is subjected to fusion analysis, a pressure sensor positions a high-risk pressed area, a high-definition color image is used for identifying macroscopic skin damage and color change, infrared thermal imaging can penetrate through a surface layer, and the image can be used for identifying the skin damage and color change. According to the method, deep tissue temperature abnormity caused by ischemia and inflammation is sensitively captured, and the three types of information are integrated into a quantitative comprehensive risk score through a weighting algorithm, so that an evaluation result does not depend on subjective experience of nursing personnel any more and is converted into objective and quantifiable accurate diagnosis, and the screening accuracy of high-risk patients is remarkably improved.