949 results about "Soft tissue" patented technology

The invention relates to the technical field of computers, discloses a tooth three-dimensional precision correction method and system based on multi-source oral data fusion, and aims to solve the problems of low registration precision, serious geometric distortion and lack of function oriented optimization of multi-modal oral data in the prior art. The method comprises the following steps: synchronously obtaining intraoral scanning, CBCT and face three-dimensional point cloud data; carrying out format conversion, denoising and grid simplification preprocessing; tooth surface morphology, root canal anatomy and soft tissue contour features are extracted and coded into uniform feature tensors; and multi-modal data space alignment is realized through staged rigid and non-rigid registration. By means of the scheme, the multi-source data fusion precision and the tooth form restoration accuracy are remarkably improved, full-process automatic efficient processing is achieved, and the clinical real-time performance and high-precision diagnosis and treatment requirements are met.

The invention relates to the technical field of medical robot systems, and discloses a nerve plexus intelligent positioning anesthesia puncture robot system based on multi-modal fusion, which performs time-space synchronization on ultrasonic image flow and contact force data. The frequency domain analysis module extracts a main peak frequency by using optical flow field frequency domain transformation, and generates a probability mask for marking pulsatile tissues. The viscoelasticity verification module calculates phase lag parameters of visual deformation and contact force, identifies tissue rheological properties and calculates a dynamic damping coefficient. The deformation compensation module calculates a mechanical residual error based on a reference mechanical model, and inversely calculates the mechanical residual error into space deformation displacement of the tissue. The feedback control module combines the probability mask and the deformation displacement to generate a motion instruction. According to the invention, through multi-modal data fusion, precise identification of tiny blood vessels, dynamic identification of tissue attributes and real-time compensation of soft tissue conceding deformation are realized.

The invention discloses a real-time pose updating method based on feature prediction and point cloud registration, and belongs to the technical field of image registration, and the method comprises the steps: extracting a bone surface point cloud which at least covers a feature region and an adjacent region from a three-dimensional model of a bone tissue of a patient, the point cloud is used as a target point cloud for registration with a real-time ultrasonic image; an ultrasonic image collected by the ultrasonic patch in real time is obtained, and a two-dimensional ultrasonic image with a spatial position is obtained; predicting the two-dimensional ultrasonic image by using a pre-trained artificial intelligence model to obtain bone-soft tissue interface features, and extracting a plurality of points on a bone-soft tissue interface from the bone-soft tissue interface to form a source point cloud for registration; and registering the source point cloud to the target point cloud to realize real-time pose updating. According to the invention, the pose monitoring in the operation can be realized through the real-time image flow under the non-invasive condition.

The invention discloses a thoracoscope minimally invasive cardiac surgery navigation system based on multi-modal image fusion, and the system comprises the steps: constructing a 5D heart digital twin containing an anatomical structure, a soft tissue boundary, metabolic activity and electrophysiological information through fusing preoperative CT, MRI, PET and intraoperative ultrasonic images; real-time dynamic registration is realized by using an electrocardio gating driven biomechanical model; superposing the multi-color coding navigation information to the visual field of the thoracoscope through a wavelength selection type spectroscope; a dynamic risk scoring model is constructed based on the distance, the speed and the tissue vulnerability, and three-level grading intervention is triggered; a miniature force feedback actuator is integrated to realize closed-loop control; and pre-operation virtual drilling and post-operation federal learning optimization are supported. The system remarkably improves the surgical precision and safety, and is suitable for high-difficulty heart minimally invasive surgeries such as mitral valve repair and atrial fibrillation ablation.

Devices, systems, and methods for predicting palatal geometry are provided. In some embodiments, a system for predicting an anatomy of a patient's palate includes one or more processors and a memory operably coupled to the one or more processors and storing instructions that, when executed by the one or more processors, cause the system to perform operations including accessing a first digital representation including an initial geometry of soft tissue corresponding to a patient's palate, determining an initial geometry of hard tissue of the patient's palate, predicting a change in the hard tissue during a treatment, using the predicted change in the hard tissue to predict a change in the soft tissue during the treatment, and outputting a second digital representation including a predicted geometry of the patient's palate at a future treatment stage of a treatment plan, based on the predicted change in the soft tissue.

The invention discloses a virtual simulation teaching method, device and equipment for cattle pregnancy diagnosis, and the method comprises the steps: constructing a three-dimensional geometric model of a cattle pelvic cavity anatomical structure, obtaining a cattle pelvic cavity model, configuring corresponding physical attribute parameters, and generating a virtual anatomical environment; receiving palpation operation of a user through force feedback equipment, driving a virtual fingertip to move in a virtual anatomy environment, and collecting user interaction data in real time; based on the motion, the operation pressure and the physical attribute parameters of the virtual fingertip, calculating an interaction force of an anatomical structure on the virtual fingertip through soft tissue physical simulation, generating a tactile feedback signal according to the interaction force, and outputting the tactile feedback signal to a user through force feedback equipment; comparing the operation track with an expert standard operation model, and guiding an operation path of the user in real time through force feedback equipment according to a comparison result; and performing skill assessment according to the diagnosis conclusion submitted by the user after completing the palpation operation and the user interaction data, and generating a diagnosis practical training report.

The invention discloses a solid ultrasonic gel patch as well as a preparation method and application thereof, and belongs to the technical field of medical chemistry. The solid ultrasonic gel patch is prepared from an acrylamide monomer, polyvinyl alcohol, sodium polyacrylate, sodium carboxymethyl cellulose, nano silicon dioxide, propylene glycol, glycerol, acrylic acid, triethanolamine, a cross-linking agent, an initiator and water according to a specific ratio. The prepared solid ultrasonic gel patch is highly matched with human soft tissue in acoustic impedance (about 1.62-1.63 * 10 < 6 > Pa.s / m), low in acoustic attenuation coefficient (less than or equal to 0.034 dB / (cm.MHz)), moderate in skin adhesion, excellent in flexibility and moisture retention, capable of solving the problems that a traditional ultrasonic coupling agent is inconvenient to use, easy to dry, poor in experience and the like, and suitable for acoustic wave conduction in ultrasonic examination and treatment.

The utility model relates to the field of medical instruments, in particular to a jaw cyst windowing and pressure reducing device. The device comprises a guide part, a connecting part and a base which are sequentially arranged from top to bottom. And the small-diameter section of the guide part is positioned at the upper part. The connecting part is a cylinder, and the diameter of the connecting part is smaller than that of the bottom of the guide part. The short axis size of the base is larger than the diameter size of the bottom of the guide part. The bottom of the base is provided with a through hole penetrating to the position above the guide part, and a drainage channel is formed. The springback characteristic of soft tissue in the bag cavity is utilized, so that the guide part and the connecting part can be fixed in the bag cavity and cannot fall off; meanwhile, through the elliptic cylindrical base, the base is effectively prevented from entering the bag cavity, the shape of the vestibular groove is met, and the wearing is free of foreign body sensation and more comfortable.

The invention relates to the technical field of artificial intelligence, in particular to an acupuncture point visual detection and positioning method and system, and the method comprises the steps: synchronously collecting multi-view three-dimensional image data and flexible multi-parameter deformation data of a target area, and the multi-view three-dimensional image data comprises body surface textures and dynamic tracks of anatomical mark points; according to the method, multi-view three-dimensional image data and flexible multi-parameter deformation data of a target area are synchronously collected, an individual deformation feature model is constructed through mark point track purification processing, then a comprehensive feature set containing real-time state and trend prediction is generated through time sequence multi-mode fusion, and after initial acupuncture point coordinates are output through an AI basic matching model, the multi-view three-dimensional image data and flexible multi-parameter deformation data of the target area are obtained. Point-by-point correction is carried out by combining an AI self-adaptive correction model with a differential deformation compensation coefficient, irregular offset and predicted offset, and model parameters are dynamically adjusted through real-time feedback calibration, so that the problem that in the prior art, only static body shape proportional positioning is relied on, and dynamic deformation of soft tissue is not considered, so that acupuncture point offset is caused is effectively solved.

The invention relates to a high-power dual-wavelength erbium-doped solid laser, and belongs to the technical field of laser. The high-power dual-wavelength erbium-doped solid laser comprises a pumping source, a pumping cavity, a diamond, a heat sink, a first resonant cavity and a second resonant cavity, the first resonant cavity comprises a first erbium-doped YAG slice crystal, and the second resonant cavity comprises a second erbium-doped YAG slice crystal. The first erbium-doped YAG sheet crystal is used for generating 1.64 [mu] m laser which oscillates back and forth in a back-and-forth light path provided by the first resonant cavity; and the second erbium-doped YAG sheet crystal is used for generating 2.94 [mu] m laser which oscillates back and forth in a back-and-forth light path provided by the second resonant cavity. According to the high-power dual-wavelength erbium-doped solid laser provided by the invention, synchronous output of 1.64 mu m and 2.94 mu m dual-wavelength laser is realized, the multifunctionality and medical adaptability of the laser are enhanced, and multi-type treatment requirements of soft tissues and hard tissues can be met at the same time.

The invention discloses bi-crosslinking self-reinforced hydrogel based on endogenous glucose in-situ initiation as well as a preparation method and application of the bi-crosslinking self-reinforced hydrogel, and relates to the technical field of biomedical materials. The double-crosslinking self-enhanced hydrogel is prepared from the following components in concentration: 1 to 3 weight percent of hyaluronic acid-tyramine, 0.8 to 1.2 weight percent of sodium alginate, 1 to 100 mmol / L of calcium carbonate, 0.0001 to 10 U / mL of horse radish peroxidase, 20 to 40 U / mL of glucose oxidase and the balance of ultrapure water. The invention also discloses an application of the double-crosslinking self-reinforced hydrogel in preparation of a filling and repairing product for soft tissue defects. The hydrogel disclosed by the invention can be filled in a tissue defect part in an injection manner, glucose in body fluid is utilized to initiate crosslinking in situ to form the hydrogel with excellent mechanical properties and long-term stability, and meanwhile, the hydrogel is good in biocompatibility and relatively high in application value.

The invention belongs to the technical field of medical biological materials, and particularly relates to a sodium hyaluronate gel regeneration filler for injection and a preparation method and application thereof.The sodium hyaluronate gel serves as a carrier to disperse acellular matrix particles, the sodium hyaluronate gel forms a micron-sized porous structure in the cross-linking process through a microbubbling technology, and the sodium hyaluronate gel is prepared into the sodium hyaluronate gel regeneration filler for injection and the preparation method and application of the sodium hyaluronate gel regeneration filler. A local cross-linked network is strengthened by combining a secondary cross-linking process, high elastic modulus is realized while the content of sodium hyaluronate is reduced, so that the porous structure has excellent instant filling and shaping capability and controllable degradation behavior, the porous structure can promote permeation of hyaluronidase, the degradation period of the hyaluronidase is matched with the tissue regeneration process, and the tissue regeneration effect is improved. And the acellular matrix particles can continuously induce adhesion, migration, proliferation and differentiation of endogenous cells of tissues, synergistically promote in-situ tissue regeneration, effectively reduce repeated injection requirements and reduce long-term complication risks, and have a good application prospect in soft tissue filling and repairing.

The invention discloses a manufacturing method of a 3D printing guide plate for a cervical vertebra single-door operation, and relates to the technical field of crossing of medical auxiliary instruments and additive manufacturing. Firstly, a cervical vertebra CT data three-dimensional reconstruction skeleton model is obtained, an operation scheme is virtually planned, then a navigation template digital prototype is generated through parameterization, finite element simulation optimization is carried out, and a three-dimensional 3D printing guide plate for the cervical vertebra single-door operation is obtained. Printing with the biocompatible resin by using light curing equipment, and finally treating to obtain a final product. According to the method, a high-precision cervical vertebra skeleton model is generated through CT thin-layer scanning and three-dimensional reconstruction, parameters of a hinge area, a door opening groove line and a nail path are determined through virtual planning, and the problem that damage or positioning deviation is easily caused due to the fact that a traditional operation depends on experience is solved; constructing a navigation template attaching curved surface by a specific algorithm, reserving a soft tissue compensation gap, matching with a hollow window bulge to limit the depth of an abrasion drill, controlling the deformation of a guide plate through finite element simulation and topological optimization, selecting specific resin to ensure the stability, ensuring the suitability by virtue of virtual registration and standardized manufacturing, and improving the accuracy, safety and efficiency of an operation.

The invention relates to the field of orthodontics, in particular to a device for controlling palatal root movement of anterior teeth of an upper jaw and a manufacturing method. According to the device, the traction arm and the traction ring which extend to the palatal side of the anterior maxillary teeth are additionally arranged on the basis of the transverse palatal bar and are matched with the traction buckle of the anterior maxillary teeth to guide orthodontic force to act below a tooth impedance center, so that root control movement which is difficult to achieve by a traditional orthodontic method is realized, bending torque on an arch wire or placing other root control devices is not needed, and the whole device is simpler and more attractive; in addition, the device part is manufactured by adopting a 3D printing technology, firstly, tooth and intraoral soft tissue data of a patient are obtained by scanning the interior of an oral cavity, then the oral scanning data are matched with CBCT, a specific device is designed by using software, finally, a finished product is directly printed in a 3D manner, the transverse palatal bar and the traction buckle are completely matched with the tooth surface by adopting the 3D printing technology, and the comfort level is high.

The invention relates to the technical field of cervical vertebra rehabilitation systems, and discloses an intelligent self-adaptive cervical vertebra rehabilitation system. The system comprises a multi-mode sensing unit which synchronously collects form data and soft tissue data of the cervical vertebra of a user through an optical mark point array and an ultrasonic probe array to generate a multi-source sensing data set; the intelligent analysis unit constructs a cervical vertebra dynamic mechanical model by using a graph convolutional neural network based on the multi-source sensing data set, analyzes a cervical vertebra joint coupling relation and stress distribution, and generates an analysis parameter set; the strategy generation unit generates a personalized rehabilitation strategy according to the analysis parameter set, the personalized rehabilitation strategy comprises an action sequence and an impedance adjustment parameter, and a strategy instruction set is formed; the dynamic control unit responds to the strategy instruction set and combines muscle activity data fed back by the electromyographic signal sensor in real time to adjust an execution strategy and generate a control command set; and the flexible driving unit drives the soft robot outer skeleton to perform multi-axis linkage rehabilitation training based on the control command set.

The invention provides a thyroid-related eye disease intraorbital soft tissue volume measurement method and system, and is applied to the technical field of data processing. Three-dimensional medical image data and system abnormal state information are obtained, the three-dimensional medical image data comprise CT images and MRI images, and the system abnormal state information comprises artifacts, isolated noisy points and irregular boundaries; data preprocessing is carried out on the three-dimensional medical image data, standardized image data is generated, and the standardized image data is formed by carrying out ternary processing on spatial registration, noise suppression and gray level normalization; processing the standardized image data and the system abnormal state information to generate an initial segmentation mask; processing the initial segmentation mask to generate an optimized mask; processing the optimized mask and the three-dimensional medical image data to generate soft tissue volume data; and processing the soft tissue volume data, the system abnormal state information and the historical volume data to generate a volume dynamic change report.

The invention relates to the technical field of orthopedic surgery, and discloses an orthopedic surgery real-time navigation system based on multi-modal image fusion and artificial intelligence. The multi-modal image fusion module is used for generating a three-dimensional skeleton and soft tissue fusion model for surgical navigation; the artificial intelligence analysis module is used for determining a fracture line, a screw implantation angle and a cutting track; the intraoperative tracking module is used for generating a real-time correction instruction; the verification updating module is used for carrying out rationality verification on the real-time correction instruction; if the inspection is not passed, an alarm mechanism is triggered, instantaneous motion state parameters of the surgical instrument are collected, the instantaneous motion state parameters are compared with the cutting track, and the correction instruction is updated according to the comparison result; and the execution module is used for driving the surgical instrument to execute the surgical operation according to the updating correction instruction. According to the invention, manual operation errors can be effectively reduced.

The invention discloses a massage quantization glove based on multi-signal fusion and a real-time feedback control system thereof. The massage quantization glove comprises a glove body, a double-layer differential sensing unit, a perturbation excitation unit, a motion detection unit, a signal processing and fusion unit and a feedback interaction unit. The double-layer differential sensing unit is composed of an outer-layer pressure sensing film, an isolation elastic layer and an inner-layer pressure sensing film and is used for collecting overall contact force and differential response signals. The perturbation excitation unit applies low-amplitude disturbance in the massage process, so that soft tissue viscoelasticity characteristics are extracted; the motion detection unit collects hand motion information and performs inertia compensation; the signal processing and fusion unit is used for denoising and analyzing the multi-source signal to generate a dose index and a hardness grade; and the feedback interaction unit prompts an operator through visual sense, auditory sense or tactile sense. Real-time quantification and feedback of massage dosage are realized, tissue hardness change can be reflected, excessive massage is avoided, curative effect consistency is improved, and massage operation standardization is promoted.

The invention belongs to the technical field of combination of biomedical engineering and intelligent monitoring, and discloses a vibration cutting tool wear state monitoring method suitable for biological soft tissue, which comprises the following steps: S1, executing vibration cutting on the biological soft tissue, and obtaining a three-channel cutting force original signal; s2, inputting the three-channel cutting force original signal into a one-dimensional residual network, and expanding the three-channel cutting force original signal into a multi-feature channel; s3, a channel attention mechanism is applied, and first enhancement is achieved for some feature channels with wear sensitivity; s4, continuing to apply the time attention mechanism, and focusing for the key time interval; s5, regression is carried out to obtain a corresponding cutter flank abrasion loss prediction value; and S6, the real-time state of the cutter is judged. Compared with the prior art, the method has the advantages that the monitoring precision and robustness in a soft tissue cutting application scene can be remarkably improved, and the high quality of subsequent microscopic optical section tomography combined with cutting, the continuity of three-dimensional modeling and the data reliability are correspondingly and effectively guaranteed.

Various examples are provided related to methods and systems to reconstruct 3D image / map for the stiffness of soft tissues. In one example, a method includes obtaining particle velocities from generated mechanical waves in tissue of a subject; reconstructing a stiffness map of soft tissue in a region of interest (ROI) from the particle velocities; and generating an image of the stiffness map for rendering on a user device. In another example, a system includes an ultrasound scanner for shear wave elastography (SWE) and a computing or processing device that can obtain particle velocities; reconstruct a stiffness map of soft tissue in a ROI from the particle velocities; and generate an image of the stiffness map for rendering. The particle velocities can be generated from acoustic radiation forces produced by the ultrasound scanner.

The present disclosure relates to a hydrogel ink comprising a lipid particle, a polynucleotide supported within the lipid particle, and a bio-ink. In one embodiment, the lipid particles comprise extracellular vesicles. The disclosure also relates to hydrogels thereof and their use in treating neurological diseases or conditions or regenerating soft tissue.

The invention relates to the technical field of biomedical materials, and discloses an active composite membrane with an asymmetric double-layer structure as well as a preparation method and application of the active composite membrane. The active composite membrane with the asymmetric double-layer structure is prepared from the following preparation raw materials in percentage by mass: 95 to 98 percent of chitosan; 0.5%-2% of a plant polyphenol cross-linking agent; and 1%-4% of magnesium-based degradable inorganic filler. The active composite membrane has an integrated double-layer structure without interface bonding, the compact layer can effectively block soft tissues, and the porous layer is beneficial to cell adhesion and nutrition delivery; in a wet state, the material is excellent in mechanical property, controllable in degradation and high in cell safety, can effectively inhibit bacteria and promote osteoblast proliferation and differentiation, and can meet the performance requirements of bone defect repair on the material; the preparation method adopts the steps of solvent volatilization, freeze drying and precooled alkaline alcohol solution washing for preparation, the whole preparation process is carried out in a water phase, the conditions are mild, the steps are simple, complex equipment is not needed, and extremely high clinical transformation and industrialization potential is shown.

Systems, devices, and methods described herein relate to generation and delivery of pulsed waveforms, e.g., for therapy delivery in soft tissue ablation procedures. In some embodiments, a pulse generator is configured to generate a voltage pulse train including a plurality of biphasic pulses, each biphasic pulse of the plurality of biphasic pulses including a positive pulse, a negative pulse, and an inter-phase delay separating the positive pulse and the negative pulse. In some embodiments, successive biphasic pulses of the plurality of biphasic pulses can be separated by a pulse-to-pulse delay such that the plurality of biphasic pulses is separated by a plurality of pulse-to-pulse delays, and the plurality of pulse-to-pulse delays can include increasing or decreasing sequences of pulse-to-pulse delays.

1. Name of the product in this design: High-frequency electrosurgical unit (Type A). 2. Intended use of this design: for soft tissue resection and coagulation. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention provides a fascia gun intelligent control method and system based on massage manipulation, and the method comprises the steps: obtaining a massage mode selected by a user in a fascia gun through the fascia gun intelligent control system, and loading a corresponding target force curve and a motion track parameter from a pre-stored manipulation parameterization library; the contact state of the fascia gun massage head and the human tissue is monitored in real time; generating a smooth expected displacement reference signal and a force reference signal; actual force, actual displacement and motor current data of the system are collected in real time; biomechanical parameters of human body soft tissue are calculated and estimated in real time, and control parameters are adjusted in a self-adaptive mode; and controlling the output force to smoothly drop to zero at a preset slope, and executing soft stop operation. The parameterized output device has the advantages that parameterized output of the fascia gun simulating various massage manipulations can be achieved, smoothness of output force is guaranteed to avoid discomfort, and self-adaptive adjustment can be conducted according to individual differences of users.

Medical devices and methods are described for removing a predetermined shape of soft tissue from a target tissue layer, leaving a matching passage having a predetermined geometry and orientation in the target tissue layer. The medical devices include coaxial outer and inner elongate members extending along an axis X; the outer member includes an open distal end and a first distal portion configured for piercing the target tissue layer during forward axial movement; the inner member includes a second distal portion configured to rotate and protrude distally through the open distal end to cut the predetermined shape of soft tissue from the target tissue layer and create the passage, which forms a hole across the target tissue layer.

The invention relates to a real-time magnetic resonance guided head gamma beam stereotactic radiotherapy system, which comprises a magnet module, a gamma beam module, a treatment bed module and a source body driving assembly, the magnet module comprises a base, a left vertical yoke and a right vertical yoke which are arranged on two sides of the base, and a left magnetic pole and a right magnetic pole which are respectively arranged on the inner side of the left vertical yoke and the inner side of the right vertical yoke; the left magnetic pole and the right magnetic pole are arranged in parallel; a Y-axis linear guide rail is arranged on the base; the gamma beam module comprises a shielding body assembly, a source body assembly and a collimation body assembly, wherein the source body assembly and the collimation body assembly are arranged in the shielding body assembly and are coaxially nested. The shielding body assembly is fixedly connected with the left vertical yoke and the right vertical yoke; the treatment bed module is arranged on the Y-axis linear guide rail, and the source body driving assembly is connected with the source body assembly. According to the invention, clear imaging of cranial soft tissue in a high field intensity environment can be realized, gamma rays are guided to carry out real-time image-guided stereotactic radiotherapy, and the radiotherapy precision is improved.

A system for repairing tears in soft tissue, e.g., meniscal tissue, by employing cinch stitching. More specifically, the present invention provides an apparatus for meniscal repair using a suture implant construct. The suture implant construct includes a first and second implant which are connected to each other via a length of suture. The implants are designed to be loaded on external surfaces of the first and second trocars.

The present invention provides a composition for reducing or eliminating vascular occlusion caused by hyaluronic acid soft tissue dermal fillers. [Solution] This disclosure provides for compositions comprising hyaluronidase, apparatus for housing such compositions, and methods and uses of such compositions and apparatus for reducing or eliminating hyaluronic acid-induced blockages in one or more blood vessels supplying an individual's eye; methods and uses of such compositions and apparatus for reducing or inhibiting vascular occlusion of an individual's eye; and methods and uses of such compositions and apparatus for reducing or inhibiting hyaluronic acid-induced vision loss in an individual.

This invention relates to a continuous-body soft tissue insertion actuator and surgical robot system based on flexible transmission, belonging to the field of medical device technology. The insertion actuator includes a base with a first through hole at its center; an insertion plate rotatably connected to the base; a drive rod passing through the first through hole and slidably connected to the base, one end of which is connected to a drive unit; a pull rod connected to the drive rod; and a transmission link, both ends of which are rotatably connected to the insertion plate and the pull rod, respectively. The drive unit drives the drive rod to move. When the pull rod moves away from the base, it drives the transmission link, causing the insertion plate to close inward, forming a conical structure. When the drive rod moves the pull rod closer to the base, the insertion plate opens under the push of the transmission link. This actuator utilizes a hyperelastic rod to transmit push and pull forces within a curved channel, combined with an offset crank-slider mechanism, to achieve powerful soft tissue insertion and separation.