36 results about "Treatment modality" patented technology

A treatment modality for use in the remediation of damaged tissues that involves protease down regulator solution impregnated microspheres, and the methods of production and therapeutic use thereof.

The invention provides an image-based tumor treatment effect evaluation method, which belongs to the technical field of treatment effect evaluation, and comprises the following steps: establishing a tumor baseline image feature library and a treatment scheme time window mapping table, and carrying out multi-time-point medical image acquisition in a treatment specificity evaluation time window; obtaining a time sequence medical image data set containing different time points after treatment, processing time sequence data by adopting tumor segmentation software and image quantitative analysis software, dynamically adjusting identification parameters according to a treatment specificity evaluation time window, and establishing a time window parameter mapping relation; tumor volume change features, density change features and boundary definition features are extracted to establish a tumor image feature change matrix, and a comprehensive treatment effect evaluation report is generated according to the image recognition result of the optimal evaluation time point. The technical problem that the treatment effect evaluation precision is insufficient due to the fact that optimal image evaluation time windows of different treatment modes are not matched is solved.

This invention provides an intelligent ultrasonic conductance directional drug penetration therapeutic device. Compared to existing technologies, this invention also includes a drug penetration module that contacts the patient's skin to apply the drug to the patient's skin, an adaptation module that adjusts the drug penetration efficiency of the drug penetration module according to the patient's skin location, and a fixation module for adapting the drug penetration module to different skin locations. This invention integrates ultrasonic treatment, drug delivery, infrared sensing, and compress clamping functions, achieving a combined application of multiple treatment methods. Utilizing ultrasonic technology, it allows drugs to penetrate the patient's skin more easily, thereby improving drug utilization.

The invention belongs to the technical field of medical data processing, and provides a multimodal fusion-based liver cancer longitudinal relapse prediction and treatment effect evaluation system, which comprises a data set construction module, which is used for forming a longitudinal queue data set by using longitudinal queue data samples of a plurality of patients, and setting a relapse time label for each longitudinal queue data sample; the training module is used for training a recurrence network by utilizing the longitudinal queue data set to obtain a recurrence model; the recurrence prediction module inputs the to-be-predicted longitudinal queue data of the patient into the recurrence model to obtain a prediction result of each treatment time point, and the prediction result comprises the recurrence probability of more than one future time period; the curative effect evaluation module is used for acquiring simulation longitudinal queue data corresponding to different treatment modes selected by the to-be-evaluated patient at the current relapse time point; and inputting the simulated longitudinal queue data into the recurrence model to obtain a prediction result of each treatment time point. According to the method, the accuracy and generalization of the recurrence model are improved, and doctors are accurately and efficiently assisted in selecting treatment modes.

The application discloses an oral orthodontic anchorage nail implantation operation patient's physical and mental state monitoring system and method, relates to the oral orthodontic treatment technical field, and comprises a patient physiological signal information acquisition unit, which is used for collecting patient physiological signal information and transmitting the patient physiological signal information to a processing and analysis unit for processing and analysis; the processing and analysis unit is used for processing and analyzing the collected patient physiological signal information, determining the patient's physical and mental state according to the patient physiological signal information, and triggering an early warning mode; and a mobile terminal platform is used for displaying the early warning mode output by the processing and analysis unit to doctors and patients and recommending a treatment mode according to the early warning mode. The application can record, analyze and feedback the patient's physical physiological information and changes before, during and after operation in a whole cycle, help doctors and nursing staff understand the real-time health condition change trend of the patient, provide guidance and support for clinical operation, help the patient better accept and adapt to the anchorage nail treatment, and improve the patient's acceptance and satisfaction.

The invention provides a medical supervision platform. A patient personal information base and a pathology big database are established; the doctor inquires the patient according to the information of the patient information base and makes corresponding diagnosis; the supervision module compares and checks the diagnosis content of the proofreading doctor through big data; after checking, doctor diagnosis is input into a patient information base, and corresponding medical resources are allocated; the patient personal information base comprises basic information of patients, past medical history, medicine allergy history, examination results and uncomfortable symptoms, the pathology big database comprises disease names, disease indications, medicine principles and treatment modes, the platform can improve the accuracy and rationality of medical diagnosis, and by checking a medicine treatment scheme of a doctor, the medical diagnosis accuracy and rationality can be improved. And the treatment mode, the medicine type and the dosage are ensured to meet medical standards and patient requirements. The proofreading steps are helpful for reducing the risk of drug treatment and improving the treatment effect of patients.

The utility model discloses an intelligent insomnia treatment system based on brain-computer interface and transcranial magnetic technology, which comprises a brain-computer interface module, a transcranial magnetic stimulation module, a central control unit and a user interaction interface, and the brain-computer interface module is electrically connected with the transcranial magnetic stimulation module. Direct communication between the human brain and external equipment is achieved by monitoring electroencephalogram signals through the brain-computer interface technology, the sleep state is affected by generating a magnetic field on the scalp surface and adjusting brain activity through the transcranial magnetic stimulation technology, the sleep state of a user can be effectively monitored and adjusted by effectively integrating the brain-computer interface technology and the transcranial magnetic stimulation technology, and the sleep state of the user can be effectively monitored and adjusted. Compared with traditional drug treatment and invasive surgery, the treatment mode does not need to be operated in the body at all, surgical risks and the postoperative recovery period are avoided, side effects caused by drug treatment are avoided, and the convenient user experience effect is achieved.

The invention discloses an electrode current output circuit and a therapeutic apparatus, and relates to the technical field of medical instruments, and the electrode current output circuit comprises an electrode current output circuit composed of at least one current output circuit, and the current output circuit comprises a current coupling unit and a coupling current output end connected with the current coupling unit. The coupling current output end is connected with one electrode piece, the radio frequency current and the electrical stimulation current are coupled and output as coupling current through the current coupling unit, and the coupling current is output from one electrode piece connected with the coupling current output end and acts on a treatment area attached to the electrode piece. The coupling current comprises the radio frequency current and the electrical stimulation current, so that the coupling current is output and acts on the treatment area attached to the electrode piece, that is, the radio frequency current and the electrical stimulation current are output and act on the same treatment area at the same time, and the problem that the treatment effect is poor in a conventional combined treatment mode is solved; and high-efficiency multi-layer combined treatment can be realized.

Provided are a monitoring device and a monitoring method thereof. The monitoring device (100) includes: a memory (104) for storing an executable program; a processor (101) for executing the program stored in the memory (104), so that the processor (101) performs the following actions, including: determining the current condition information of the monitored subject based on at least two types of physiological parameters of the monitored subject; generating processing information of a treatment tool associated with the current condition information based on the current condition information, wherein the processing information includes parameter information when a treatment method corresponding to the treatment tool is used on the monitored subject, and / or the processing information includes prompt information corresponding to the treatment tool; a display (103) for at least displaying the physiological parameters on a display interface; and displaying the processing information on the display interface when the processing information is acquired.

The present invention relates to methods for tuning treatment parameters in movement disorder therapy systems. The present invention further relates to a system for screening patients to determine viability as candidates for certain therapy modalities, such as deep brain stimulation (DBS). The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of tuning a therapy device using objective quantified movement disorder symptom data acquired by a movement disorder diagnostic device to determine the therapy setting or parameters to be provided to the subject via his or her therapy device. The present invention also provides treatment and tuning remotely, allowing for home monitoring of subjects.

The invention discloses an irradiation head structure of a millimeter wave therapeutic instrument, and belongs to the technical field of medical instruments. A rotating ring rotates in the shell; a movable frame is arranged on the rotating ring through a supporting cross beam; a radiation head is arranged on the movable frame, a rolling piece is arranged on the movable frame, a fixed disc is arranged in the shell, an inner ring groove and an outer ring groove are formed in the lower surface of the fixed disc, a connecting groove is formed between the inner ring groove and the outer ring groove, the rolling piece rolls in the inner ring groove or the outer ring groove, and a step is arranged at the connecting position of the groove bottom of the inner ring groove and the connecting groove. A rotating plate is rotationally arranged at the connecting position of the outer ring groove and the connecting groove. According to the invention, rapid switching of treatment modes can be realized. When single-area irradiation treatment and large-area irradiation treatment are mutually switched, the rolling piece can enter the inner ring groove from the outer ring groove along the connecting groove or enter the outer ring groove from the inner ring groove along the connecting groove only by controlling the motor to change the rotating direction of the rotating ring, complex operation and additional devices are not needed, and treatment modes can be rapidly changed.

The present application belongs to the technical field of medical data processing, and provides a liver cancer longitudinal recurrence prediction and treatment efficacy evaluation system based on multi-modal fusion, comprising: a data set construction module, which uses multiple patient longitudinal cohort data samples to form a longitudinal cohort data set, and sets a recurrence time label for each longitudinal cohort data sample; a training module, which trains a recurrence network using the longitudinal cohort data set to obtain a recurrence model; a recurrence prediction module, which inputs the patient's to-be-predicted longitudinal cohort data into the recurrence model to obtain prediction results at each treatment time point, the prediction results including the recurrence probability of more than one future time period; and an efficacy evaluation module, which obtains simulated longitudinal cohort data corresponding to different treatment methods at the current recurrence time point of the patient to be evaluated; and inputs the simulated longitudinal cohort data into the recurrence model to obtain prediction results at each treatment time point. The present application improves the accuracy and generalizability of the recurrence model, and accurately and efficiently assists doctors in selecting treatment methods.

One or more new metrics are introduced into the treatment planning process. More specifically, a correcting factor / metric referred to herein as the critical / repair ratio index is introduced, and / or a correcting factor / metric referred to herein as the spatial periodicity of critical isodose value is introduced. By using these metrics, the expected sparing from the spatial distribution of dose is better accounted for in treatment modalities including spatially fractionated radiation therapy (SFRT) in general and SFRT with ultra-high dose rates in particular. According to a treatment planning strategy, the target can be covered by a Spread-Out Bragg Peak, to optimize and / or homogenize the dose distribution at the target level but still benefit from the sparing effect of SFRT at the healthy tissue level. Delivery techniques include a dynamic focusing technique and a magnetic beam steering technique. Enhancing dose rate enables maximizing the peak-to-valley dose distribution with SFRT despite patient motion.

Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.

The utility model discloses a portable multifunctional dressing device, and belongs to the technical field of dressings. The annular dressing is composed of an annular dressing body, a multifunctional double-fixing device and a connecting lacing. A hollow medicine applying area and a female hook-and-loop fastener are arranged on an annular dressing body, one end of a connecting tying belt is connected to the dressing body in front of the female hook-and-loop fastener, and a multifunctional fixing device composed of a rectangular shell layer with a zipper at the top end and a fixing belt is connected to the dressing body behind the hollow medicine applying area through the inner side end. A heat preservation layer is arranged in the shell layer, and a heating or cold compressing material is arranged in the heat preservation layer; a secondary magic tape is arranged on the inner side surface of the shell layer, a fixing band is arranged at the outer side end of the shell layer, a connecting buckle is arranged at the top end of the fixing band, and a thumb fixing hole is further formed in the annular dressing body. The device facilitates replacement of therapeutic drugs and physical therapy modes, is light and heat-insulating in material, is convenient to wear and take off, and does not affect work and study when being worn, so that the recovery efficiency is improved.

The invention discloses a traditional Chinese medicine fumigation and deep spectrum combined therapeutic apparatus, and relates to the technical field of medical equipment. The traditional Chinese medicine fumigation combined deep spectrum therapeutic apparatus comprises a fumigation main body, a supporting arm assembly and a spectrum therapeutic device, the supporting arm assembly is rotatably arranged on the fumigation main body; the spectrum treatment device is arranged on the supporting arm assembly, and the supporting arm assembly is used for adjusting the height and the light emitting angle of the spectrum treatment device. The structure of the therapeutic apparatus is improved, the convenience of fumigation treatment and spectrum treatment is improved, the two treatment modes can achieve a synergistic effect, the treatment requirements of different patients can be met, and the treatment effect and efficiency are remarkably improved.

The technical field of the application is brain low-energy photon treatment equipment, and specifically discloses an extracorporeal transcranial therapeutic instrument. The therapeutic instrument is mainly composed of a protective shell, a treatment window and a beta ray source, and forms a closed container cavity, the beta ray source is located inside the cavity, the treatment window is designed to be provided with a beta ray filter sheet which is completely matched with the window area specification, the beta ray filter sheet filters out harmful beta rays, and low-energy photons are generated in the process, and effective treatment of patients is realized. The extracorporeal transcranial therapeutic instrument has many advantages, first, it is a non-invasive treatment method, which avoids the risk of traumatic surgery; second, it is easy and flexible to operate, and can meet the needs of different patients, especially in emergency situations; in addition, it is low in cost and has no radiation pollution, which also wins the favor of many users.

The present disclosure relates to methods for determining at least one treatment modality of a dialysis treatment of a specific patient depending on at least one value out of the group of values, a first value reflecting the overhydration (OH) of the patient, a second value reflecting the salinity or osmolarity of the patient, a third value reflecting the blood pressure of the patient, a fourth value reflecting the renal function of the patient, a fifth value reflecting a heart issue the patient, a sixth value reflecting hypotension of the patient, a seventh value reflecting vessel conditions, and an eighth value reflecting a total protein content of the patient. Herein, an algorithm or reference material is used. Furthermore, the disclosure relates to devices for executing this method and processing the results of the method.

The invention discloses a lymphedema rehabilitation system and method based on multi-modal integration, relates to the technical field of rehabilitation assistance, and has the technical key points that the rehabilitation system and method greatly improve the treatment effect by virtue of multiple innovative functions. According to the invention, accurate synchronization and deep complementation of infrared thermal imaging evaluation, audio nerve regulation, meridian mechanical stimulation and pressure treatment are realized, and the synergistic interaction characteristic of each treatment mode is fully embodied; by means of the infrared thermal imaging technology, the lymphatic circulation abnormal part is accurately recognized, the autonomic nerve state is adjusted through guiding audio, and the physiological function and the psychological emotion can be optimized at the same time in cooperation with targeted meridian intervention and pressure therapy, so that the physical and psychological health is effectively promoted, the scientificity and pertinence of treatment are remarkably enhanced, and the treatment cost is reduced. And the accuracy and individuation of the treatment effect are ensured.

The invention relates to the technical field of medical devices, in particular to an intelligent temperature control brachytherapy source applicator external member which comprises a source applicator and an external member body. The outer side of the advancing end of the source applicator is provided with an outer sleeve piece used for conducting deep regional thermal therapy on a patient, one side of the outer sleeve piece is provided with a heat insulation sleeve for achieving the heat insulation purpose, and the center of the heat insulation sleeve is provided with a mounting groove; wherein the interior of the mounting groove is matched with thermal therapy pieces with two thermal therapy modes, and the thermal therapy pieces are divided into a first thermal therapy piece and a second thermal therapy piece; temperature monitoring modules for temperature monitoring are mounted in the heat insulation sleeve at the upper and lower parts of the mounting groove; one end of the source applicator is provided with the external sleeve member, one side of the external sleeve member is provided with the thermal therapy member used for heating for treatment, when radiotherapy is carried out, the thermal therapy member with controllable temperature is started to carry out deep regional thermal therapy, and the radiotherapy and the thermal therapy are matched, so that the tumor treatment effect of a patient is better.

The invention discloses an antioxidant skin medical system, which specifically comprises a patient skin data information acquisition module, a patient skin data information analysis processing module, a multi-mode parallel combination deep treatment module and a patient skin condition monitoring feedback module, according to the invention, comprehensive combined treatment can be carried out on a patient according to a personalized treatment scheme in various different treatment modes, and the skin oxidative stress problem of the patient is treated through different treatment modes and different treatment angles by adopting various intervention measures of basic nursing, oral administration of medicines, external application of medicines and anti-oxidation treatment; according to the method, accurate intervention is effectively performed aiming at the skin problem of the patient, the skin aging phenomenon of the patient is improved, the skin health is promoted, the skin condition change of the patient is monitored by utilizing a multi-parameter skin analyzer, and meanwhile, the experience feedback of the patient is collected, so that the treatment effect is ensured, the treatment scheme is adjusted in time, and the skin injury caused by oxidative stress is reduced.

The invention relates to an oral soft and hard tissue change prediction and curative effect comparison method and system, and the system can automatically recognize anatomical mark points on any head shadow X-ray film or three-dimensional image based on a method, namely a self-developed image measurement algorithm, and builds a unified coordinate system based on orbital ear planes. The influence of the patient shooting posture difference on the mark point position measurement is eliminated; according to the method, a linear prediction equation between hard tissue and soft tissue changes is further constructed, the changes of the hard tissue and the soft tissue in different treatment modes are predicted in combination with individual characteristics of patients, and objective and quantitative curative effect comparison results are generated. According to the method, the soft and hard tissue displacement can be quantified in a standardized mode, the measurement consistency is remarkably improved, personalized treatment scheme selection is supported, and the limitation that traditional head shadow measurement is high in subjectivity and lacks repeatability is overcome.

The present disclosure concerns the development of personalised periodontitis score to assess the individual level of microbial imbalances in periodontal pockets and / or saliva of a specific individual at a defined stage of treatment, relative to a predicted expected score for the average patient with similar systemic and local medical characteristics and demographic profile. The microbial profile obtained from genetic / genomic information is combined with clinical and demographical information in a mixed-effect model to obtain a predicted value and a standard error for a given set of clinical parameters. The comparison between this predicted average score and the individual patient personalised periodontitis score informs about the relative periodontal disease activity in this site and / or patient and thus allows for the stratification of the local site and / or the patient into risk categories and for the recommendation of targeted patient-specific treatment modalities.

A computer-implemented method (300) for processing a sample image of a condition is disclosed, the method comprising: processing (305) a sample image by a set of computer vision models for treatment patterns associated with a condition to obtain a set of decisions associated with a plurality of predictive diagnoses for the condition; processing (310) the sample image to determine a relevant visual embedding to be used as a query for querying a database; querying (315) a database to retrieve first k most similar entries from the database based on vector similarities between the determined visual embedding and corresponding keys in the plurality of entries; and processing (320) the sample image by a medically trained talent base model (GFM) using the obtained set of decisions as a reference context and images corresponding to the retrieved first k most similar entries to make a predictive decision on a condition displayed by the sample image.

Presented herein are systems and methods that provide for automated analysis of three-dimensional (3D) medical images of a subject in order to automatically identify specific 3D volumes within the 3D images that correspond to specific anatomical regions (e.g., organs and / or tissue). Notably, the image analysis approaches described herein are not limited to a single particular organ or portion of the body. Instead, they are robust and widely applicable, providing for consistent, efficient, and accurate detection of anatomical regions, including soft tissue organs, in the entire body. In certain embodiments, the accurate identification of one or more such volumes is used to automatically determine quantitative metrics that represent uptake of radiopharmaceuticals in particular organs and / or tissue regions. These uptake metrics can be used to assess disease state in a subject, determine a prognosis for a subject, and / or determine efficacy of a treatment modality.

A treatment modality for use in the remediation of damaged tissues that involves protease down regulator solution impregnated microspheres, and the methods of production and therapeutic use thereof.

A multimodality treatment plan including one or more of, for example, surgery, radiotherapy and a systemic treatment such as chemotherapy, may be obtained by robust co-optimization of two or more plans taking into account uncertainties affecting each treatment modality as well as uncertainties resulting from the combination of the modalities. Scenarios may be defined for the different uncertainties to be used in the optimization. The plans may be optimized simultaneously, or one plan may be optimized considering the predicted effect of another plan of another modality.

This invention belongs to the field of biomedicine, specifically relating to a combination drug composition for Ph+ALL and its application. This invention discloses a combination drug composition for Ph+ALL, characterized by comprising a BCL-2 inhibitor, a demethylating agent, and a TKI. The technical solution of this invention expands the chemotherapy-free treatment modality for Ph+ALL, not only enabling patients to achieve rapid and deep remission while observing no unacceptable treatment-related toxicities, but also significantly improving the quality of life of treatment-naïve patients, reducing treatment-related complications, decreasing the consumption of blood products, shortening hospital stays, and significantly reducing medical insurance expenditures.

Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders, and other diseases.

A support system configured to support the lower extremities of a patient, for example during radiotherapy and imaging procedures, and methods for employing the same is provided. The support system includes a knee support apparatus and a foot support apparatus, each of which may be used together or independently in order to customize the support needed for the particular procedure. When used on the patient table of an appropriate imaging or treatment modality, the support system is configured to allow the clinician to independently adjust the knee support and foot support's positioning in the superior-inferior axis of the patient table in both a gross and fine manner for optimal positioning of the patient for the target procedure. The robust adjustment capabilities of the support system enable enhanced patient comfort, setup reproducibility, and workflow efficiency.